12,13-DHOA (BioDeep_00001872290)

Main id: BioDeep_00000002665

 


代谢物信息卡片


(9Z)-12,13-Dihydroxyoctadec-9-enoic acid

化学式: C18H34O4 (314.2457)
中文名称:
谱图信息: 最多检出来源 Rattus norvegicus(feces) 13.73%

分子结构信息

SMILES: CCCCCC(C(C/C=C\CCCCCCCC(=O)O)O)O
InChI: InChI=1S/C18H34O4/c1-2-3-10-13-16(19)17(20)14-11-8-6-4-5-7-9-12-15-18(21)22/h8,11,16-17,19-20H,2-7,9-10,12-15H2,1H3,(H,21,22)/b11-8-

描述信息

A DiHOME obtained by formal dihydroxylation of the 12,13-double bond of octadeca-9,12-dienoic acid (the 9Z-geoisomer).

同义名列表

6 个代谢物同义名

(9Z)-12,13-Dihydroxyoctadec-9-enoic acid; 12,13-dihydroxy-9Z-octadecenoic acid; 12,13-DiHOME; 12,13-DHOME; 12,13-DHOA; FA 18:1;O2



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 APOE, CD36, EGFR, FGF21, NOS1, PPARG, S100A12, SLC27A1
Peripheral membrane protein 3 CYP1B1, NOS1, S100A12
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 3 CYP1B1, EGFR, SLC27A1
Nucleus 6 APOE, EGFR, NOS1, PLTP, PPARG, S100A12
cytosol 6 EPHX2, LEP, NOS1, PPARG, PRKCQ, S100A12
dendrite 1 APOE
phagocytic vesicle 1 CD36
nucleoplasm 2 NOS1, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 4 CD36, EGFR, S100A12, SLC27A1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 2 CD36, UCP1
Synapse 1 NOS1
cell junction 1 EGFR
cell surface 3 ADIPOQ, CD36, EGFR
glutamatergic synapse 2 APOE, EGFR
Golgi apparatus 2 APOE, CD36
Golgi membrane 2 EGFR, INS
mitochondrial inner membrane 1 UCP1
neuronal cell body 1 APOE
sarcolemma 1 NOS1
endosome 1 EGFR
plasma membrane 8 APOE, CD36, EGFR, NOS1, NRG4, PRKCQ, S100A12, SLC27A1
Membrane 6 APOE, CD36, CYP1B1, EGFR, NRG4, SLC27A1
apical plasma membrane 2 CD36, EGFR
basolateral plasma membrane 1 EGFR
caveola 1 CD36
extracellular exosome 2 APOE, EPHX2
endoplasmic reticulum 3 ADIPOQ, APOE, SLC27A1
extracellular space 12 ADIPOQ, APOE, CD36, CSF3, EGFR, FGF21, IL6, INS, LEP, MSTN, NRG4, PLTP
lysosomal lumen 1 CSF3
perinuclear region of cytoplasm 3 EGFR, NOS1, PPARG
mitochondrion 3 CYP1B1, NOS1, UCP1
protein-containing complex 2 EGFR, NOS1
intracellular membrane-bounded organelle 2 CYP1B1, PPARG
Microsome membrane 1 CYP1B1
postsynaptic density 1 NOS1
Single-pass type I membrane protein 2 EGFR, NRG4
Secreted 10 ADIPOQ, APOE, CSF3, FGF21, IL6, INS, LEP, MSTN, PLTP, S100A12
extracellular region 10 ADIPOQ, APOE, CSF3, FGF21, IL6, INS, LEP, NRG4, PLTP, S100A12
Single-pass membrane protein 1 SLC27A1
centriolar satellite 1 PRKCQ
photoreceptor inner segment 1 NOS1
nuclear membrane 1 EGFR
external side of plasma membrane 1 CD36
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 2 APOE, PLTP
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
dendritic spine 1 NOS1
Early endosome 1 APOE
Apical cell membrane 1 CD36
Cell membrane, sarcolemma 1 NOS1
Cytoplasm, perinuclear region 1 NOS1
Mitochondrion inner membrane 1 UCP1
Membrane raft 3 CD36, EGFR, NOS1
Cytoplasm, cytoskeleton 1 S100A12
focal adhesion 1 EGFR
extracellular matrix 1 APOE
Peroxisome 1 EPHX2
collagen trimer 2 ADIPOQ, CD36
intracellular vesicle 1 EGFR
sarcoplasmic reticulum 1 NOS1
peroxisomal matrix 1 EPHX2
Cell projection, dendritic spine 1 NOS1
collagen-containing extracellular matrix 2 ADIPOQ, APOE
receptor complex 3 CD36, EGFR, PPARG
chromatin 1 PPARG
cell periphery 2 CD36, NOS1
cytoskeleton 2 NOS1, S100A12
Secreted, extracellular space 1 APOE
brush border membrane 1 CD36
blood microparticle 1 APOE
Endomembrane system 1 SLC27A1
endosome lumen 1 INS
specific granule membrane 1 CD36
Melanosome 1 APOE
basal plasma membrane 2 EGFR, SLC27A1
synaptic membrane 1 EGFR
secretory granule lumen 2 INS, S100A12
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 APOE, IL6, INS
endocytic vesicle membrane 1 CD36
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
clathrin-coated endocytic vesicle membrane 2 APOE, EGFR
synaptic cleft 1 APOE
platelet alpha granule membrane 1 CD36
discoidal high-density lipoprotein particle 1 APOE
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
endocytic vesicle lumen 2 APOE, CSF3
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
interleukin-6 receptor complex 1 IL6
[Pro-neuregulin-4, membrane-bound isoform]: Cell membrane 1 NRG4
[Neuregulin-4]: Secreted 1 NRG4


文献列表

  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]