1-Pyrroline (BioDeep_00001871861)

Main id: BioDeep_00000010824

 


代谢物信息卡片


3,4-Dihydro-2H-pyrrole

化学式: C4H7N (69.0578)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 22.97%

分子结构信息

SMILES: C1CC=NC1
InChI: InChI=1S/C4H7N/c1-2-4-5-3-1/h3H,1-2,4H2

描述信息

同义名列表

3 个代谢物同义名

3,4-Dihydro-2H-pyrrole; 1-Pyrroline; 1-Pyrroline



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABI1, ABI3, ARG1, CAT, CTPS1, DHPS, DLK1, GPX1, OAT, PAOX
Peripheral membrane protein 2 AOC1, HSD17B6
Nucleus 4 ABI1, ARG1, GPX4, ZFP62
cytosol 10 ABI1, ARG1, CAT, CTPS1, DHPS, GPX1, GPX4, GSR, LIPE, PAOX
nucleoplasm 2 OAT, PRODH
Cell membrane 2 AOC1, LIPE
lamellipodium 2 ABI1, ABI3
Cell projection, growth cone 1 ABI1
Cytoplasmic granule 1 ARG1
Early endosome membrane 1 HSD17B6
dendritic shaft 1 ABI3
glutamatergic synapse 1 ABI3
Golgi apparatus 1 FUT2
Golgi membrane 1 FUT2
growth cone 1 ABI1
mitochondrial inner membrane 2 OTC, PRODH
Cytoplasm, cytosol 2 CTPS1, LIPE
plasma membrane 1 AOC1
Membrane 5 ABI3, CAT, CTPS1, DLK1, LIPE
caveola 1 LIPE
extracellular exosome 6 ABI1, AOC1, CAT, FUT2, GPX4, GSR
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 ABI1, HSD17B6
extracellular space 3 AOC1, ARG1, DLK1
bicellular tight junction 1 AOC1
mitochondrion 8 CAT, GPX1, GPX4, GSR, OAT, OTC, PRODH, PYCR1
protein-containing complex 2 CAT, GPX4
intracellular membrane-bounded organelle 3 CAT, HSD17B6, PRODH
Microsome membrane 1 HSD17B6
filopodium 1 ABI1
postsynaptic density 2 ABI1, ABI3
extracellular region 3 AOC1, ARG1, CAT
Single-pass membrane protein 1 DLK1
Mitochondrion matrix 2 OAT, OTC
mitochondrial matrix 7 CAT, GPX1, GSR, OAT, OTC, PRODH, PYCR1
Extracellular side 1 AOC1
external side of plasma membrane 1 GSR
dendritic spine 1 ABI3
Single-pass type II membrane protein 1 FUT2
Cell projection, lamellipodium 1 ABI1
filopodium tip 1 ABI1
Cytoplasm, cytoskeleton 1 ABI1
focal adhesion 1 CAT
Peroxisome 3 AOC1, CAT, PAOX
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, PAOX
peroxisomal membrane 1 CAT
Cell projection, filopodium 1 ABI1
cytoskeleton 1 ABI1
Secreted, extracellular space 1 AOC1
nuclear envelope 1 GPX4
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Golgi cisterna membrane 1 FUT2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
specific granule lumen 2 AOC1, ARG1
azurophil granule lumen 1 ARG1
Golgi apparatus, Golgi stack membrane 1 FUT2
catalase complex 1 CAT
[Isoform Mitochondrial]: Mitochondrion 1 GPX4
cytoophidium 1 CTPS1
[Isoform Cytoplasmic]: Cytoplasm 1 GPX4
SCAR complex 2 ABI1, ABI3
actin-based cell projection 2 ABI1, ABI3


文献列表

  • Haowen Luo, Bin Du, Longxin He, Jing He, Lian Hu, Shenggang Pan, Xiangru Tang. Exogenous application of zinc (Zn) at the heading stage regulates 2-acetyl-1-pyrroline (2-AP) biosynthesis in different fragrant rice genotypes. Scientific reports. 2019 12; 9(1):19513. doi: 10.1038/s41598-019-56159-7. [PMID: 31862962]
  • Heidi Rose Bokesch, Roberta Scott Gardella, Daniel Christopher Rabe, Donald Paul Bottaro, William Marston Linehan, James Brislin McMahon, Tawnya Carlene McKee. A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots and stems of Piper sarmentosum. Chemical & pharmaceutical bulletin. 2011; 59(9):1178-9. doi: 10.1248/cpb.59.1178. [PMID: 21881266]
  • Marcia Levin Pelchat, Cathy Bykowski, Fujiko F Duke, Danielle R Reed. Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. Chemical senses. 2011 Jan; 36(1):9-17. doi: 10.1093/chemse/bjq081. [PMID: 20876394]
  • Panagiotis N Moschou, Kalliopi A Roubelakis-Angelakis. Characterization, assay, and substrate specificity of plant polyamine oxidases. Methods in molecular biology (Clifton, N.J.). 2011; 720(?):183-94. doi: 10.1007/978-1-61779-034-8_11. [PMID: 21318874]
  • Gavin M George, Margaretha J van der Merwe, Adriano Nunes-Nesi, Rolene Bauer, Alisdair R Fernie, Jens Kossmann, James R Lloyd. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. Plant physiology. 2010 Sep; 154(1):55-66. doi: 10.1104/pp.110.157776. [PMID: 20605913]
  • Jean Robert Rapin, Nicolas Wiernsperger. Possible links between intestinal permeability and food processing: A potential therapeutic niche for glutamine. Clinics (Sao Paulo, Brazil). 2010 Jun; 65(6):635-43. doi: 10.1590/s1807-59322010000600012. [PMID: 20613941]
  • Machender R Kandadi, Prabhakar K Rajanna, Mazhuvancherry K Unnikrishnan, Sai P Boddu, Yinan Hua, Ji Li, Min Du, Jun Ren, Nair Sreejayan. 2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a novel, synthetic small molecule that alleviates insulin resistance and lipid abnormalities. Biochemical pharmacology. 2010 Feb; 79(4):623-31. doi: 10.1016/j.bcp.2009.09.018. [PMID: 19769946]
  • Jia-Qiang Zhang, Zhi-Wei Zhang, Ling Hui, Xuan Tian. Design, synthesis and biological evaluation of novel spin-labeled derivatives of podophyllotoxin. Natural product communications. 2010 Feb; 5(2):241-4. doi: . [PMID: 20334135]
  • K Sakthivel, R M Sundaram, N Shobha Rani, S M Balachandran, C N Neeraja. Genetic and molecular basis of fragrance in rice. Biotechnology advances. 2009 Jul; 27(4):468-73. doi: 10.1016/j.biotechadv.2009.04.001. [PMID: 19371779]
  • Hong-Wei Xue, Xu Chen, Yu Mei. Function and regulation of phospholipid signalling in plants. The Biochemical journal. 2009 Jun; 421(2):145-56. doi: 10.1042/bj20090300. [PMID: 19552624]
  • Panagiotis N Moschou, Maite Sanmartin, Athina H Andriopoulou, Enrique Rojo, Jose J Sanchez-Serrano, Kalliopi A Roubelakis-Angelakis. Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis. Plant physiology. 2008 Aug; 147(4):1845-57. doi: 10.1104/pp.108.123802. [PMID: 18583528]
  • Maria Esther Rubio-Ruiz, Eulises Díaz-Díaz, Mario Cárdenas-León, Rabindranath Argüelles-Medina, Patricia Sánchez-Canales, Fernando Larrea-Gallo, Elizabeth Soria-Castro, Verónica Guarner-Lans. Glycation does not modify bovine serum albumin (BSA)-induced reduction of rat aortic relaxation: the response to glycated and nonglycated BSA is lost in metabolic syndrome. Glycobiology. 2008 Jul; 18(7):517-25. doi: 10.1093/glycob/cwn034. [PMID: 18458031]
  • Yuming Zhang, Chongzhao Ran, Guangyin Zhou, Lawrence M Sayre. Highly potent 3-pyrroline mechanism-based inhibitors of bovine plasma amine oxidase and mass spectrometric confirmation of cofactor derivatization. Bioorganic & medicinal chemistry. 2007 Feb; 15(4):1868-77. doi: 10.1016/j.bmc.2006.11.025. [PMID: 17150363]
  • Klaus Stolze, Natascha Rohr-Udilova, Thomas Rosenau, Roswitha Stadtmüller, Hans Nohl. Very stable superoxide radical adducts of 5-ethoxycarbonyl- 3,5-dimethyl-pyrroline N-oxide (3,5-EDPO) and its derivatives. Biochemical pharmacology. 2005 May; 69(9):1351-61. doi: 10.1016/j.bcp.2005.01.019. [PMID: 15826606]
  • J Apelt, S Grassmann, X Ligneau, H H Pertz, C R Ganellin, J M Arrang, J C Schwartz, W Schunack, H Stark. Search for histamine H3 receptor antagonists with combined inhibitory potency at Ntau-methyltransferase: ether derivatives. Die Pharmazie. 2005 Feb; 60(2):97-106. doi: NULL. [PMID: 15739896]
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  • Yoshimasa Aso, Keishi Takanashi, Kyouichi Sekine, Noboru Yoshida, Kohzo Takebayashi, Kazuhiro Yoshihara, Toshihiko Inukai. Dissociation between urinary pyrraline and pentosidine concentrations in diabetic patients with advanced nephropathy. The Journal of laboratory and clinical medicine. 2004 Aug; 144(2):92-9. doi: 10.1016/j.lab.2004.03.016. [PMID: 15322503]
  • Aneta Koceva-Chyła, Adam Sokal, Katarzyna Kania, Krzysztof Gwoździński, Zofia Jóźwiak. The nitroxides pirolin and pirolid protect the plasma membranes of rat cardiomyocytes against damage induced by anthracyclines. Cellular & molecular biology letters. 2003; 8(1):171-7. doi: NULL. [PMID: 12655371]
  • Aneta Koceva-Chyła, Krzysztof Gwoździński, Agata Kochman, Aneta Stolarska, Zofia Jóźwiak. Effects of pyrroline and pyrrolidine nitroxides on lipid peroxidation in heart tissue of rats treated with doxorubicin. Cellular & molecular biology letters. 2003; 8(1):179-83. doi: ". [PMID: 12655372]
  • Robert Halmosi, Peter Deres, Ambrus Toth, Zoltan Berente, Tamas Kalai, Balazs Sumegi, Kalman Hideg, Kalman Toth. 2,2,5,5-Tetramethylpyrroline-based compounds in prevention of oxyradical-induced myocardial damage. Journal of cardiovascular pharmacology. 2002 Dec; 40(6):854-67. doi: 10.1097/00005344-200212000-00006. [PMID: 12451318]
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