Bisbenzimide (BioDeep_00001871857)

Main id: BioDeep_00000008535

 

Volatile Flavor Compounds


代谢物信息卡片


Hoechst 33342

化学式: C27H28N6O (452.2324478)
中文名称: 赫斯特荧光染料33342
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOC1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N6CCN(CC6)C
InChI: InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D020011 - Protective Agents > D011837 - Radiation-Protective Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes
D011838 - Radiation-Sensitizing Agents

同义名列表

4 个代谢物同义名

Hoechst 33342; Bisbenzimide; Hoe 33342; Hoechst 33342



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Margarida M Cordeiro, Hugo A L Filipe, Patrícia Dos Santos, Jaime Samelo, João P Prates Ramalho, Luís M S Loura, Maria J Moreno. Interaction of Hoechst 33342 with POPC Membranes at Different pH Values. Molecules (Basel, Switzerland). 2023 Jul; 28(15):. doi: 10.3390/molecules28155640. [PMID: 37570608]
  • Kakishi Uno, Nagisa Sugimoto, Yoshikatsu Sato. N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging. Nature communications. 2021 05; 12(1):2650. doi: 10.1038/s41467-021-23019-w. [PMID: 33976192]
  • Hongyan Ma, Huiyun Liang, Shengxin Cai, Barry R O'Keefe, Susan L Mooberry, Robert H Cichewicz. An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures. Journal of natural products. 2021 03; 84(3):750-761. doi: 10.1021/acs.jnatprod.0c00946. [PMID: 33226219]
  • Feifan Wang, Min Cao, Mengjing Fan, Hongshen Wu, Wei Huang, Yan Zhang, Zhenghui Hu, Xiaodong Jin. AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells. Journal of cellular physiology. 2020 05; 235(5):4302-4315. doi: 10.1002/jcp.29307. [PMID: 31621074]
  • L Manzini, S Halwachs, F Girolami, P Badino, W Honscha, C Nebbia. Interaction of mammary bovine ABCG2 with AFB1 and its metabolites and regulation by PCB 126 in a MDCKII in vitro model. Journal of veterinary pharmacology and therapeutics. 2017 Dec; 40(6):591-598. doi: 10.1111/jvp.12397. [PMID: 28198024]
  • Thanyaluck Siriyong, Potjanee Srimanote, Sasitorn Chusri, Boon-Ek Yingyongnarongkul, Channarong Suaisom, Varomyalin Tipmanee, Supayang Piyawan Voravuthikunchai. Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa. BMC complementary and alternative medicine. 2017 Aug; 17(1):405. doi: 10.1186/s12906-017-1913-y. [PMID: 28806947]
  • Nikita Devnarain, Charlette Tiloke, Savania Nagiah, Anil A Chuturgoon. Fusaric acid induces oxidative stress and apoptosis in human cancerous oesophageal SNO cells. Toxicon : official journal of the International Society on Toxinology. 2017 Feb; 126(?):4-11. doi: 10.1016/j.toxicon.2016.12.006. [PMID: 27956242]
  • Sandra Halwachs, Ingo Schäfer, Carsten Kneuer, Peter Seibel, Walther Honscha. Assessment of ABCG2-mediated transport of pesticides across the rabbit placenta barrier using a novel MDCKII in vitro model. Toxicology and applied pharmacology. 2016 08; 305(?):66-74. doi: 10.1016/j.taap.2016.06.007. [PMID: 27288731]
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  • Yu Hsuan Carol Yang, Jocelyn E Manning Fox, Kevin L Zhang, Patrick E MacDonald, James D Johnson. Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion. Proceedings of the National Academy of Sciences of the United States of America. 2013 Oct; 110(41):16480-5. doi: 10.1073/pnas.1214312110. [PMID: 24065825]
  • Jana Mandíková, Marie Volková, Petr Pávek, Michal Česnek, Zlatko Janeba, Vladimír Kubíček, František Trejtnar. Interactions with selected drug renal transporters and transporter-mediated cytotoxicity in antiviral agents from the group of acyclic nucleoside phosphonates. Toxicology. 2013 Sep; 311(3):135-46. doi: 10.1016/j.tox.2013.07.004. [PMID: 23856525]
  • Wenguang Chang, Ming Zhang, Jing Li, Zhaojie Meng, Shengnan Wei, Hongwei Du, Li Chen, Grant M Hatch. Berberine improves insulin resistance in cardiomyocytes via activation of 5'-adenosine monophosphate-activated protein kinase. Metabolism: clinical and experimental. 2013 Aug; 62(8):1159-67. doi: 10.1016/j.metabol.2013.02.007. [PMID: 23537779]
  • Rupak Doshi, Hendrik W van Veen. Substrate binding stabilizes a pre-translocation intermediate in the ATP-binding cassette transport protein MsbA. The Journal of biological chemistry. 2013 Jul; 288(30):21638-47. doi: 10.1074/jbc.m113.485714. [PMID: 23766512]
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  • Adam T Clay, Frances J Sharom. Lipid bilayer properties control membrane partitioning, binding, and transport of p-glycoprotein substrates. Biochemistry. 2013 Jan; 52(2):343-54. doi: 10.1021/bi301532c. [PMID: 23268645]
  • Christina Janko, Luis Munoz, Ricardo Chaurio, Christian Maueröder, Christian Berens, Kirsten Lauber, Martin Herrmann. Navigation to the graveyard-induction of various pathways of necrosis and their classification by flow cytometry. Methods in molecular biology (Clifton, N.J.). 2013; 1004(?):3-15. doi: 10.1007/978-1-62703-383-1_1. [PMID: 23733565]
  • Frank A D T G Wagener, Anita C A Dankers, Frank van Summeren, Alwin Scharstuhl, Jeroen J M W van den Heuvel, Jan B Koenderink, Sebastiaan W C Pennings, Frans G M Russel, Rosalinde Masereeuw. Heme Oxygenase-1 and breast cancer resistance protein protect against heme-induced toxicity. Current pharmaceutical design. 2013; 19(15):2698-707. doi: 10.2174/1381612811319150004. [PMID: 23092328]
  • Lucy T T Tran-Nguyen, Bernd Schneider. Cesium chloride-bisbenzimide gradients for separation of phytoplasma and plant DNA. Methods in molecular biology (Clifton, N.J.). 2013; 938(?):381-93. doi: 10.1007/978-1-62703-089-2_32. [PMID: 22987432]
  • Ye Tian, Bo-Xuan Qu, Yan Yao, Su Zeng. [Establishment of BCRP expressed pig kidney cell line LLC-PK1/BCRP and its biological profile]. Yao xue xue bao = Acta pharmaceutica Sinica. 2012 Dec; 47(12):1599-604. doi: NULL. [PMID: 23460964]
  • Jake S Burrell, Simon Walker-Samuel, Lauren C J Baker, Jessica K R Boult, Yann Jamin, Anderson J Ryan, John C Waterton, Jane Halliday, Simon P Robinson. Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas. International journal of cancer. 2012 Oct; 131(8):1854-62. doi: 10.1002/ijc.27460. [PMID: 22290271]
  • Krishna P Kota, Jacqueline G Benko, Rajini Mudhasani, Cary Retterer, Julie P Tran, Sina Bavari, Rekha G Panchal. High content image based analysis identifies cell cycle inhibitors as regulators of Ebola virus infection. Viruses. 2012 Sep; 4(10):1865-77. doi: 10.3390/v4101865. [PMID: 23202445]
  • Zizhang Ouyang, Shaohua Zhu, Jing Jin, Jia Li, Yuwen Qiu, Min Huang, Zhiying Huang. Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells. Die Pharmazie. 2012 Aug; 67(8):725-32. doi: . [PMID: 22957440]
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  • Man C Cheung, James G Evans, Brian McKenna, Daniel J Ehrlich. Deep ultraviolet mapping of intracellular protein and nucleic acid in femtograms per pixel. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2011 Nov; 79(11):920-32. doi: 10.1002/cyto.a.21111. [PMID: 21796773]
  • Chuanpit Ninsontia, Kanittha Pongjit, Chatchai Chaotham, Pithi Chanvorachote. Silymarin selectively protects human renal cells from cisplatin-induced cell death. Pharmaceutical biology. 2011 Oct; 49(10):1082-90. doi: 10.3109/13880209.2011.568506. [PMID: 21591838]
  • Juyoung Kim, Hyejeong Yun, Yunhi Cho. Analysis of ceramide metabolites in differentiating epidermal keratinocytes treated with calcium or vitamin C. Nutrition research and practice. 2011 Oct; 5(5):396-403. doi: 10.4162/nrp.2011.5.5.396. [PMID: 22125676]
  • Jana Balbuena, Gisela Pachon, Guillermo Lopez-Torrents, Josep M Aran, Javier S Castresana, Jordi Petriz. ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2011 Sep; 79(9):672-83. doi: 10.1002/cyto.a.21103. [PMID: 21774076]
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  • Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Thévenod. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. 2011 Jun; 121(2):343-56. doi: 10.1093/toxsci/kfr071. [PMID: 21436125]
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