Bisbenzimide (BioDeep_00001871857)
Main id: BioDeep_00000008535
代谢物信息卡片
Hoechst 33342
化学式: C27H28N6O (452.2324)
中文名称: 赫斯特荧光染料33342
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N6CCN(CC6)C
InChI: InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31)
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D020011 - Protective Agents > D011837 - Radiation-Protective Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes
D011838 - Radiation-Sensitizing Agents
同义名列表
4 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:51232
- KEGG: C11189
- PubChem: 1464
- ChEMBL: CHEMBL343002
- CAS: 23491-52-3
- PubChem: 13370
- PDB-CCD: HT1
- NIKKAJI: J283.606H
- KNApSAcK: 51232
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Margarida M Cordeiro, Hugo A L Filipe, Patrícia Dos Santos, Jaime Samelo, João P Prates Ramalho, Luís M S Loura, Maria J Moreno. Interaction of Hoechst 33342 with POPC Membranes at Different pH Values.
Molecules (Basel, Switzerland).
2023 Jul; 28(15):. doi:
10.3390/molecules28155640. [PMID: 37570608] - Kakishi Uno, Nagisa Sugimoto, Yoshikatsu Sato. N-aryl pyrido cyanine derivatives are nuclear and organelle DNA markers for two-photon and super-resolution imaging.
Nature communications.
2021 05; 12(1):2650. doi:
10.1038/s41467-021-23019-w. [PMID: 33976192] - Hongyan Ma, Huiyun Liang, Shengxin Cai, Barry R O'Keefe, Susan L Mooberry, Robert H Cichewicz. An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures.
Journal of natural products.
2021 03; 84(3):750-761. doi:
10.1021/acs.jnatprod.0c00946. [PMID: 33226219] - Feifan Wang, Min Cao, Mengjing Fan, Hongshen Wu, Wei Huang, Yan Zhang, Zhenghui Hu, Xiaodong Jin. AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Journal of cellular physiology.
2020 05; 235(5):4302-4315. doi:
10.1002/jcp.29307. [PMID: 31621074] - L Manzini, S Halwachs, F Girolami, P Badino, W Honscha, C Nebbia. Interaction of mammary bovine ABCG2 with AFB1 and its metabolites and regulation by PCB 126 in a MDCKII in vitro model.
Journal of veterinary pharmacology and therapeutics.
2017 Dec; 40(6):591-598. doi:
10.1111/jvp.12397. [PMID: 28198024] - Thanyaluck Siriyong, Potjanee Srimanote, Sasitorn Chusri, Boon-Ek Yingyongnarongkul, Channarong Suaisom, Varomyalin Tipmanee, Supayang Piyawan Voravuthikunchai. Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa.
BMC complementary and alternative medicine.
2017 Aug; 17(1):405. doi:
10.1186/s12906-017-1913-y. [PMID: 28806947] - Nikita Devnarain, Charlette Tiloke, Savania Nagiah, Anil A Chuturgoon. Fusaric acid induces oxidative stress and apoptosis in human cancerous oesophageal SNO cells.
Toxicon : official journal of the International Society on Toxinology.
2017 Feb; 126(?):4-11. doi:
10.1016/j.toxicon.2016.12.006. [PMID: 27956242] - Sandra Halwachs, Ingo Schäfer, Carsten Kneuer, Peter Seibel, Walther Honscha. Assessment of ABCG2-mediated transport of pesticides across the rabbit placenta barrier using a novel MDCKII in vitro model.
Toxicology and applied pharmacology.
2016 08; 305(?):66-74. doi:
10.1016/j.taap.2016.06.007. [PMID: 27288731] - Kristin M Bircsak, Vivek Gupta, Poi Yu Sofia Yuen, Ludwik Gorczyca, Barry I Weinberger, Anna M Vetrano, Lauren M Aleksunes. Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter.
The Journal of pharmacology and experimental therapeutics.
2016 Apr; 357(1):103-13. doi:
10.1124/jpet.115.230185. [PMID: 26850786] - Sandra Halwachs, Carsten Kneuer, Katrin Gohlsch, Marian Müller, Vera Ritz, Walther Honscha. The ABCG2 efflux transporter from rabbit placenta: Cloning and functional characterization.
Placenta.
2016 Feb; 38(?):8-15. doi:
10.1016/j.placenta.2015.12.005. [PMID: 26907376] - Manu Smriti Singh, Kapil Juvale, Michael Wiese, Alf Lamprecht. Evaluation of dual P-gp-BCRP inhibitors as nanoparticle formulation.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2015 Sep; 77(?):1-8. doi:
10.1016/j.ejps.2015.04.027. [PMID: 25976226] - Hyuk-Sang Jeong, In-geun Ryoo, Mi-Kyoung Kwak. Regulation of the expression of renal drug transporters in KEAP1-knockdown human tubular cells.
Toxicology in vitro : an international journal published in association with BIBRA.
2015 Aug; 29(5):884-92. doi:
10.1016/j.tiv.2015.03.013. [PMID: 25841332] - Abigail M Dalzell, Pratibha Mistry, Jayne Wright, Faith M Williams, Colin D A Brown. Characterization of multidrug transporter-mediated efflux of avermectins in human and mouse neuroblastoma cell lines.
Toxicology letters.
2015 Jun; 235(3):189-98. doi:
10.1016/j.toxlet.2015.04.005. [PMID: 25865432] - I S Haslam, C El-Chami, H Faruqi, A Shahmalak, C A O'Neill, R Paus. Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle.
The British journal of dermatology.
2015 Jun; 172(6):1562-1572. doi:
10.1111/bjd.13549. [PMID: 25418064] - Allan Sauvat, Yidan Wang, Florian Segura, Sabrina Spaggiari, Kevin Müller, Heng Zhou, Lorenzo Galluzzi, Oliver Kepp, Guido Kroemer. Quantification of cellular viability by automated microscopy and flow cytometry.
Oncotarget.
2015 Apr; 6(11):9467-75. doi:
10.18632/oncotarget.3266. [PMID: 25816366] - Bart Lammertink, Roel Deckers, Gert Storm, Chrit Moonen, Clemens Bos. Duration of ultrasound-mediated enhanced plasma membrane permeability.
International journal of pharmaceutics.
2015 Mar; 482(1-2):92-8. doi:
10.1016/j.ijpharm.2014.12.013. [PMID: 25497443] - Guo Bo Quan, Yuan Ma, Jian Li, Guo Quan Wu, Dong Jiang Li, Yi Na Ni, Chun Rong Lv, Lan Zhu, Qiong Hua Hong. Effects of Hoechst33342 staining on the viability and flow cytometric sex-sorting of frozen-thawed ram sperm.
Cryobiology.
2015 Feb; 70(1):23-31. doi:
10.1016/j.cryobiol.2014.11.002. [PMID: 25481668] - Vineet Kumar, Bhagwat Prasad, Gabriela Patilea, Anshul Gupta, Laurent Salphati, Raymond Evers, Cornelis E C A Hop, Jashvant D Unadkat. Quantitative transporter proteomics by liquid chromatography with tandem mass spectrometry: addressing methodologic issues of plasma membrane isolation and expression-activity relationship.
Drug metabolism and disposition: the biological fate of chemicals.
2015 Feb; 43(2):284-8. doi:
10.1124/dmd.114.061614. [PMID: 25488931] - Matias Ekstrand, Maria Gustafsson Trajkovska, Jeanna Perman-Sundelin, Per Fogelstrand, Martin Adiels, Martin Johansson, Lillemor Mattsson-Hultén, Jan Borén, Max Levin. Imaging of Intracellular and Extracellular ROS Levels in Atherosclerotic Mouse Aortas Ex Vivo: Effects of Lipid Lowering by Diet or Atorvastatin.
PloS one.
2015; 10(6):e0130898. doi:
10.1371/journal.pone.0130898. [PMID: 26098110] - Jian Zheng, Mei Jing Piao, Ki Cheon Kim, Cheng Wen Yao, Ji Won Cha, Seong Min Kim, Chang Lim Hyun, Sungwook Chae, Yong Seok Ahn, Jin Won Hyun. Americanin B protects cultured human keratinocytes against oxidative stress by exerting antioxidant effects.
In vitro cellular & developmental biology. Animal.
2014 Sep; 50(8):766-77. doi:
10.1007/s11626-014-9759-9. [PMID: 24825376] - Sandra Halwachs, Louise Wassermann, Walther Honscha. A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides.
Toxicology in vitro : an international journal published in association with BIBRA.
2014 Apr; 28(3):432-41. doi:
10.1016/j.tiv.2013.12.015. [PMID: 24389113] - Yon-Suk Kim, Jin-Woo Hwang, Young-Ki Han, Hyuck-Ju Kwon, Heeok Hong, Ee-Hwa Kim, Sang-Ho Moon, Byong-Tae Jeon, Pyo-Jam Park. Antioxidant activity and protective effects of Trapa japonica pericarp extracts against tert-butylhydroperoxide-induced oxidative damage in Chang cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2014 Feb; 64(?):49-56. doi:
10.1016/j.fct.2013.11.018. [PMID: 24269339] - Min-Cheol Kang, Kil-Nam Kim, Sung-Myung Kang, Xiudong Yang, Eun-A Kim, Choon Bok Song, Jae-Woon Nah, Mi-Kyeong Jang, Jung-Suck Lee, Won-Kyo Jung, You-Jin Jeon. Protective effect of dieckol isolated from Ecklonia cava against ethanol caused damage in vitro and in zebrafish model.
Environmental toxicology and pharmacology.
2013 Nov; 36(3):1217-26. doi:
10.1016/j.etap.2013.09.018. [PMID: 24189014] - Abbas Azadmehr, Keyvan Alizadeh Oghyanous, Reza Hajiaghaee, Zahra Amirghofran, Mohammad Azadbakht. Antioxidant and neuroprotective effects of Scrophularia striata extract against oxidative stress-induced neurotoxicity.
Cellular and molecular neurobiology.
2013 Nov; 33(8):1135-41. doi:
10.1007/s10571-013-9979-7. [PMID: 23999721] - Yu Hsuan Carol Yang, Jocelyn E Manning Fox, Kevin L Zhang, Patrick E MacDonald, James D Johnson. Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Oct; 110(41):16480-5. doi:
10.1073/pnas.1214312110. [PMID: 24065825] - Jana Mandíková, Marie Volková, Petr Pávek, Michal Česnek, Zlatko Janeba, Vladimír Kubíček, František Trejtnar. Interactions with selected drug renal transporters and transporter-mediated cytotoxicity in antiviral agents from the group of acyclic nucleoside phosphonates.
Toxicology.
2013 Sep; 311(3):135-46. doi:
10.1016/j.tox.2013.07.004. [PMID: 23856525] - Wenguang Chang, Ming Zhang, Jing Li, Zhaojie Meng, Shengnan Wei, Hongwei Du, Li Chen, Grant M Hatch. Berberine improves insulin resistance in cardiomyocytes via activation of 5'-adenosine monophosphate-activated protein kinase.
Metabolism: clinical and experimental.
2013 Aug; 62(8):1159-67. doi:
10.1016/j.metabol.2013.02.007. [PMID: 23537779] - Rupak Doshi, Hendrik W van Veen. Substrate binding stabilizes a pre-translocation intermediate in the ATP-binding cassette transport protein MsbA.
The Journal of biological chemistry.
2013 Jul; 288(30):21638-47. doi:
10.1074/jbc.m113.485714. [PMID: 23766512] - C A Burroughs, J K Graham, R W Lenz, G E Seidel. Seminal plasma effects on sex-sorting bovine sperm.
Theriogenology.
2013 Feb; 79(3):551-7. doi:
10.1016/j.theriogenology.2012.10.024. [PMID: 23244767] - Adam T Clay, Frances J Sharom. Lipid bilayer properties control membrane partitioning, binding, and transport of p-glycoprotein substrates.
Biochemistry.
2013 Jan; 52(2):343-54. doi:
10.1021/bi301532c. [PMID: 23268645] - Christina Janko, Luis Munoz, Ricardo Chaurio, Christian Maueröder, Christian Berens, Kirsten Lauber, Martin Herrmann. Navigation to the graveyard-induction of various pathways of necrosis and their classification by flow cytometry.
Methods in molecular biology (Clifton, N.J.).
2013; 1004(?):3-15. doi:
10.1007/978-1-62703-383-1_1. [PMID: 23733565] - Frank A D T G Wagener, Anita C A Dankers, Frank van Summeren, Alwin Scharstuhl, Jeroen J M W van den Heuvel, Jan B Koenderink, Sebastiaan W C Pennings, Frans G M Russel, Rosalinde Masereeuw. Heme Oxygenase-1 and breast cancer resistance protein protect against heme-induced toxicity.
Current pharmaceutical design.
2013; 19(15):2698-707. doi:
10.2174/1381612811319150004. [PMID: 23092328] - Lucy T T Tran-Nguyen, Bernd Schneider. Cesium chloride-bisbenzimide gradients for separation of phytoplasma and plant DNA.
Methods in molecular biology (Clifton, N.J.).
2013; 938(?):381-93. doi:
10.1007/978-1-62703-089-2_32. [PMID: 22987432] - Ye Tian, Bo-Xuan Qu, Yan Yao, Su Zeng. [Establishment of BCRP expressed pig kidney cell line LLC-PK1/BCRP and its biological profile].
Yao xue xue bao = Acta pharmaceutica Sinica.
2012 Dec; 47(12):1599-604. doi:
NULL. [PMID: 23460964] - Jake S Burrell, Simon Walker-Samuel, Lauren C J Baker, Jessica K R Boult, Yann Jamin, Anderson J Ryan, John C Waterton, Jane Halliday, Simon P Robinson. Evaluation of novel combined carbogen USPIO (CUSPIO) imaging biomarkers in assessing the antiangiogenic effects of cediranib (AZD2171) in rat C6 gliomas.
International journal of cancer.
2012 Oct; 131(8):1854-62. doi:
10.1002/ijc.27460. [PMID: 22290271] - Krishna P Kota, Jacqueline G Benko, Rajini Mudhasani, Cary Retterer, Julie P Tran, Sina Bavari, Rekha G Panchal. High content image based analysis identifies cell cycle inhibitors as regulators of Ebola virus infection.
Viruses.
2012 Sep; 4(10):1865-77. doi:
10.3390/v4101865. [PMID: 23202445] - Zizhang Ouyang, Shaohua Zhu, Jing Jin, Jia Li, Yuwen Qiu, Min Huang, Zhiying Huang. Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells.
Die Pharmazie.
2012 Aug; 67(8):725-32. doi:
. [PMID: 22957440] - O J Nøstbakken, I L Bredal, P A Olsvik, T S Huang, B E Torstensen. Effect of marine omega 3 fatty acids on methylmercury-induced toxicity in fish and mammalian cells in vitro.
Journal of biomedicine & biotechnology.
2012; 2012(?):417652. doi:
10.1155/2012/417652. [PMID: 22654480] - Ryan Christensen, Luis de la Torre-Ubieta, Azad Bonni, Daniel A Colón-Ramos. A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development.
Development (Cambridge, England).
2011 Dec; 138(23):5257-67. doi:
10.1242/dev.069062. [PMID: 22069193] - Man C Cheung, James G Evans, Brian McKenna, Daniel J Ehrlich. Deep ultraviolet mapping of intracellular protein and nucleic acid in femtograms per pixel.
Cytometry. Part A : the journal of the International Society for Analytical Cytology.
2011 Nov; 79(11):920-32. doi:
10.1002/cyto.a.21111. [PMID: 21796773] - Chuanpit Ninsontia, Kanittha Pongjit, Chatchai Chaotham, Pithi Chanvorachote. Silymarin selectively protects human renal cells from cisplatin-induced cell death.
Pharmaceutical biology.
2011 Oct; 49(10):1082-90. doi:
10.3109/13880209.2011.568506. [PMID: 21591838] - Juyoung Kim, Hyejeong Yun, Yunhi Cho. Analysis of ceramide metabolites in differentiating epidermal keratinocytes treated with calcium or vitamin C.
Nutrition research and practice.
2011 Oct; 5(5):396-403. doi:
10.4162/nrp.2011.5.5.396. [PMID: 22125676] - Jana Balbuena, Gisela Pachon, Guillermo Lopez-Torrents, Josep M Aran, Javier S Castresana, Jordi Petriz. ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties.
Cytometry. Part A : the journal of the International Society for Analytical Cytology.
2011 Sep; 79(9):672-83. doi:
10.1002/cyto.a.21103. [PMID: 21774076] - N Hagen, M Hans, D Hartmann, D Swandulla, G van Echten-Deckert. Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism.
Cell death and differentiation.
2011 Aug; 18(8):1356-65. doi:
10.1038/cdd.2011.7. [PMID: 21331079] - Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Thévenod. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport.
Toxicological sciences : an official journal of the Society of Toxicology.
2011 Jun; 121(2):343-56. doi:
10.1093/toxsci/kfr071. [PMID: 21436125] - Jian Zou, Xiao-Feng Yu, Zhi-Jun Bao, Jie Dong. Proteome of human colon cancer stem cells: a comparative analysis.
World journal of gastroenterology.
2011 Mar; 17(10):1276-85. doi:
10.3748/wjg.v17.i10.1276. [PMID: 21455326] - Dong Wang, Laura M Jones, Peter E Urwin, Howard J Atkinson. A synthetic peptide shows retro- and anterograde neuronal transport before disrupting the chemosensation of plant-pathogenic nematodes.
PloS one.
2011 Mar; 6(3):e17475. doi:
10.1371/journal.pone.0017475. [PMID: 21408216] - Jun-Jie Pan, Hai-Ming Shi, Xin-Ping Luo, Duan Ma, Yong Li, Jun Zhu, Wang Liang, Jin-Gui Mu, Jian Li. Recombinant TFPI-2 enhances macrophage apoptosis through upregulation of Fas/FasL.
European journal of pharmacology.
2011 Mar; 654(2):135-41. doi:
10.1016/j.ejphar.2010.12.015. [PMID: 21192924] - Mark I Garvey, M Mukhlesur Rahman, Simon Gibbons, Laura J V Piddock. Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria.
International journal of antimicrobial agents.
2011 Feb; 37(2):145-51. doi:
10.1016/j.ijantimicag.2010.10.027. [PMID: 21194895] - Beata Kosmider, Elise M Messier, Hong Wei Chu, Robert J Mason. Human alveolar epithelial cell injury induced by cigarette smoke.
PloS one.
2011; 6(12):e26059. doi:
10.1371/journal.pone.0026059. [PMID: 22163265] - Holger Erfle, Tautvydas Lisauskas, Christoph Claas, Jürgen Reymann, Vytaute Starkuviene. Cell arrays for the measurement of organelle dynamics in living cells.
Methods in molecular biology (Clifton, N.J.).
2011; 706(?):73-81. doi:
10.1007/978-1-61737-970-3_6. [PMID: 21104055] - Amina El Ayadi, Michael J Zigmond. Low concentrations of methamphetamine can protect dopaminergic cells against a larger oxidative stress injury: mechanistic study.
PloS one.
2011; 6(10):e24722. doi:
10.1371/journal.pone.0024722. [PMID: 22022363] - Marina Isshiki, Kazuo Umezawa, Hiroomi Tamura. Coffee induces breast cancer resistance protein expression in Caco-2 cells.
Biological & pharmaceutical bulletin.
2011; 34(10):1624-7. doi:
10.1248/bpb.34.1624. [PMID: 21963506] - Inmaculada Posadas, Pablo Santos, Almudena Blanco, Maríangeles Muñoz-Fernández, Valentín Ceña. Acetaminophen induces apoptosis in rat cortical neurons.
PloS one.
2010 Dec; 5(12):e15360. doi:
10.1371/journal.pone.0015360. [PMID: 21170329] - D Ito, H Tamate, M Nagayama, T Uchida, S N Kudoh, K Gohara. Minimum neuron density for synchronized bursts in a rat cortical culture on multi-electrode arrays.
Neuroscience.
2010 Nov; 171(1):50-61. doi:
10.1016/j.neuroscience.2010.08.038. [PMID: 20800660] - Myriam Catalá, Francisco Gasulla, Ana E Pradas del Real, Francisco García-Breijo, Jose Reig-Armiñana, Eva Barreno. Fungal-associated NO is involved in the regulation of oxidative stress during rehydration in lichen symbiosis.
BMC microbiology.
2010 Nov; 10(?):297. doi:
10.1186/1471-2180-10-297. [PMID: 21092214] - Sascha Karassek, Carsten Berghaus, Melanie Schwarten, Christoph G Goemans, Nadine Ohse, Gerd Kock, Katharina Jockers, Sebastian Neumann, Sebastian Gottfried, Christian Herrmann, Rolf Heumann, Raphael Stoll. Ras homolog enriched in brain (Rheb) enhances apoptotic signaling.
The Journal of biological chemistry.
2010 Oct; 285(44):33979-91. doi:
10.1074/jbc.m109.095968. [PMID: 20685651] - Sylvie Poluch, Sharon L Juliano. Populations of radial glial cells respond differently to reelin and neuregulin1 in a ferret model of cortical dysplasia.
PloS one.
2010 Oct; 5(10):e13709. doi:
10.1371/journal.pone.0013709. [PMID: 21060844] - Nathalia Vitureira, Rosa Andrés, Esther Pérez-Martínez, Albert Martínez, Ana Bribián, Juan Blasi, Shierley Chelliah, Guillermo López-Doménech, Fernando De Castro, Ferran Burgaya, Kelly McNagny, Eduardo Soriano. Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation.
PloS one.
2010 Aug; 5(8):e12003. doi:
10.1371/journal.pone.0012003. [PMID: 20706633] - Sara Nannizzi, Gareth J Veal, Elisa Giovannetti, Valentina Mey, Simona Ricciardi, Christopher J Ottley, Mario Del Tacca, Romano Danesi. Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines.
Cancer chemotherapy and pharmacology.
2010 Aug; 66(3):547-58. doi:
10.1007/s00280-009-1195-2. [PMID: 20020129] - Ellen Wernike, Willy Hofstetter, Yuelian Liu, Gang Wu, Hans-Jörg Sebald, Daniel Wismeijer, Ernst B Hunziker, Klaus-Arno Siebenrock, Frank M Klenke. Long-term cell-mediated protein release from calcium phosphate ceramics.
Journal of biomedical materials research. Part A.
2010 Feb; 92(2):463-74. doi:
10.1002/jbm.a.32411. [PMID: 19195029] - A Al-Malki, S Newton, S E Francis, K El-Ghariani. Circulating endothelial cells in whole blood donations and the effect of leucodepletion.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.
2010 Feb; 42(1):97-9. doi:
10.1016/j.transci.2009.10.011. [PMID: 19932983] - Geise Ribeiro, Marcel Benadiba, Denise de Oliveira Silva, Alison Colquhoun. The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro.
Cell biochemistry and function.
2010 Jan; 28(1):15-23. doi:
10.1002/cbf.1626. [PMID: 19927275] - Soma Datta, Shibnath Mazumder, Debabrata Ghosh, Saibal Dey, Shelley Bhattacharya. Low concentration of arsenic could induce caspase-3 mediated head kidney macrophage apoptosis with JNK-p38 activation in Clarias batrachus.
Toxicology and applied pharmacology.
2009 Dec; 241(3):329-38. doi:
10.1016/j.taap.2009.09.007. [PMID: 19782097] - Edmond Kahn, Sophie Pelloux, Mauhamad Baarine, Taoufik Khalfaoui, Kévin Ragot, Frédérique Frouin, Jean-Marc Riedinger, Yves Tourneur, Gérard Lizard. Analysis of the capture and influence of nanoparticles on the cytotoxic effects of 7-ketocholesterol on cardiac cells: investigation by flow cytometry and by dynamic and spectral imaging microscopy associated with factor analysis of medical image sequences.
Analytical and quantitative cytology and histology.
2009 Dec; 31(6):380-94. doi:
NULL. [PMID: 20698354] - Therese Bredholt, Elizabeth Ao Dimba, Hanne R Hagland, Line Wergeland, Jørn Skavland, Kjell O Fossan, Karl J Tronstad, Anne C Johannessen, Olav K Vintermyr, Bjørn T Gjertsen. Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines.
Molecular cancer.
2009 Nov; 8(?):101. doi:
10.1186/1476-4598-8-101. [PMID: 19912650] - Sun Ha Lee, Tae-Hyun Yoo, Bo-Young Nam, Dong Ki Kim, Jin Ji Li, Dong-Sub Jung, Seung-Jae Kwak, Dong-Ryeol Ryu, Seung Hyeok Han, Jung Eun Lee, Sung Jin Moon, Dae Suk Han, Shin-Wook Kang. Activation of local aldosterone system within podocytes is involved in apoptosis under diabetic conditions.
American journal of physiology. Renal physiology.
2009 Nov; 297(5):F1381-90. doi:
10.1152/ajprenal.00101.2009. [PMID: 19710242] - Pradeep Tyagi, Vikas Tyagi, Naoki Yoshimura, Erich Witteemer, Derek Barclay, Patricia A Loughran, Ruben Zamora, Yoram Vodovotz. Gender-based reciprocal expression of transforming growth factor-beta1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis.
Journal of inflammation (London, England).
2009 Aug; 6(?):23. doi:
10.1186/1476-9255-6-23. [PMID: 19691848] - Jin Boo Jeong, Eul Won Seo, Hyung Jin Jeong. Effect of extracts from pine needle against oxidative DNA damage and apoptosis induced by hydroxyl radical via antioxidant activity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Aug; 47(8):2135-41. doi:
10.1016/j.fct.2009.05.034. [PMID: 19500637] - Tetsuo Mashima, Shigeo Sato, Sachiko Okabe, Satoshi Miyata, Masaaki Matsuura, Yoshikazu Sugimoto, Takashi Tsuruo, Hiroyuki Seimiya. Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.
Cancer science.
2009 Aug; 100(8):1556-62. doi:
10.1111/j.1349-7006.2009.01203.x. [PMID: 19459852] - Baohong Jiang, Lin Zhang, Yingchun Wang, Ming Li, Wanying Wu, Shuhong Guan, Xuan Liu, Min Yang, Junchen Wang, De-an Guo. Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2009 Jul; 47(7):1538-44. doi:
10.1016/j.fct.2009.03.038. [PMID: 19358873] - Zheng Chen, Zhengzheng Li, Gong Peng, Xiaoli Chen, Wenxuan Yin, Michael I Kotlikoff, Zeng-Qiang Yuan, Guangju Ji. Extracellular ATP-induced nuclear Ca2+ transient is mediated by inositol 1,4,5-trisphosphate receptors in mouse pancreatic beta-cells.
Biochemical and biophysical research communications.
2009 May; 382(2):381-4. doi:
10.1016/j.bbrc.2009.03.030. [PMID: 19285037] - Jinghong Zhao, Yunjian Huang, Yaoming Song, Xiaohui Zhao, Jun Jin, Junping Wang, Lan Huang. Low osmolar contrast medium induces cellular injury and disruption of calcium homeostasis in rat glomerular endothelial cells in vitro.
Toxicology letters.
2009 Mar; 185(2):124-31. doi:
10.1016/j.toxlet.2008.12.009. [PMID: 19136047] - Takahiro Ueno, Noboru Fukuda, Akiko Tsunemi, En-Hui Yao, Hiroyuki Matsuda, Kazunobu Tahira, Taro Matsumoto, Koichi Matsumoto, Yoshiaki Matsumoto, Hiroki Nagase, Hiroshi Sugiyama, Tatsuya Sawamura. A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function.
Journal of hypertension.
2009 Mar; 27(3):508-16. doi:
10.1097/hjh.0b013e3283207fe1. [PMID: 19330905] - Haitao Ge, Xiuqin Kong, Limei Shi, Lijuan Hou, Zhili Liu, Ping Li. Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells.
Cell biology international.
2009 Mar; 33(3):402-10. doi:
10.1016/j.cellbi.2009.01.014. [PMID: 19356705] - María Sol Brassesco, Ana Paula Montaldi, Elza Tiemi Sakamoto-Hojo. Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide.
Genetics and molecular biology.
2009 Jan; 32(1):144-50. doi:
10.1590/s1415-47572009000100022. [PMID: 21637660] - Anne Vejux, Stéphane Guyot, Thomas Montange, Jean-Marc Riedinger, Edmond Kahn, Gérard Lizard. Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis.
The Journal of nutritional biochemistry.
2009 Jan; 20(1):45-61. doi:
10.1016/j.jnutbio.2007.12.001. [PMID: 18495460] - Eun-Young Lee, Pan-Young Jeong, Sun-Young Kim, Yhong-Hee Shim, David J Chitwood, Young-Ki Paik. Effects of sterols on the development and aging of Caenorhabditis elegans.
Methods in molecular biology (Clifton, N.J.).
2009; 462(?):167-79. doi:
10.1007/978-1-60327-115-8_11. [PMID: 19160668] - Lipeng Wang, Markos Leggas, Mamta Goswami, Philip E Empey, Patrick J McNamara. N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin transfer into milk.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Dec; 36(12):2591-6. doi:
10.1124/dmd.108.021980. [PMID: 18799806] - Isao Kobayashi, Hiroko Kusakabe, Hideaki Toda, Tadaaki Moritomo, Tomoko Takahashi, Teruyuki Nakanishi. In vivo characterization of primitive hematopoietic cells in clonal ginbuna crucian carp (Carassius auratus langsdorfii).
Veterinary immunology and immunopathology.
2008 Nov; 126(1-2):74-82. doi:
10.1016/j.vetimm.2008.06.008. [PMID: 18674821] - Jong Bin Kim, Eunyoung Ko, Wonshik Han, Incheol Shin, Seo Young Park, Dong-Young Noh. Berberine diminishes the side population and ABCG2 transporter expression in MCF-7 breast cancer cells.
Planta medica.
2008 Nov; 74(14):1693-700. doi:
10.1055/s-0028-1088313. [PMID: 18951337] - Grzegorz Wicher, Asa Fex-Svenningsen, Isabel Velsecchi, Yves Charnay, Hakan Aldskogius. Extracellular clusterin promotes neuronal network complexity in vitro.
Neuroreport.
2008 Oct; 19(15):1487-91. doi:
10.1097/wnr.0b013e32830fe4d1. [PMID: 18797303] - Sanjai K Addla, Mick D Brown, Claire A Hart, Vijay A C Ramani, Noel W Clarke. Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells.
American journal of physiology. Renal physiology.
2008 Sep; 295(3):F680-7. doi:
10.1152/ajprenal.90286.2008. [PMID: 18614618] - In-Hwan Lee, Hui-Young Kim, Myunghye Kim, Ji-Sook Hahn, Seung R Paik. Dequalinium-induced cell death of yeast expressing alpha-synuclein-GFP fusion protein.
Neurochemical research.
2008 Jul; 33(7):1393-400. doi:
10.1007/s11064-008-9598-8. [PMID: 18322792] - Zhigang Wang, Xiaobo Tang, Yumei Li, Changlian Leu, Lei Guo, Xiaodong Zheng, Daling Zhu. 20-Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells.
European journal of pharmacology.
2008 Jun; 588(1):9-17. doi:
10.1016/j.ejphar.2008.03.045. [PMID: 18455723] - Kou Motani, Keiichi Tabata, Yumiko Kimura, Soichiro Okano, Yasuko Shibata, Yoshimitsu Abiko, Hisashi Nagai, Toshihiro Akihisa, Takashi Suzuki. Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma.
Biological & pharmaceutical bulletin.
2008 Apr; 31(4):618-26. doi:
10.1248/bpb.31.618. [PMID: 18379052] - Tamás I Orbán, László Seres, Csilla Ozvegy-Laczka, N Barry Elkind, Balázs Sarkadi, László Homolya. Combined localization and real-time functional studies using a GFP-tagged ABCG2 multidrug transporter.
Biochemical and biophysical research communications.
2008 Mar; 367(3):667-73. doi:
10.1016/j.bbrc.2007.12.172. [PMID: 18182157] - P Zhou, D J Liu, M Cang, Y Z Ma, D S Yang, H J Li, L M Wang, S Bou, H L Feng. TGFalpha and EGFR in ovine preimplantation embryos and effects on development.
Animal reproduction science.
2008 Mar; 104(2-4):370-81. doi:
10.1016/j.anireprosci.2007.02.024. [PMID: 17412533] - M Suzuki, T Tanaka. Development of Meteorus pulchricornis and regulation of its noctuid host, Pseudaletia separata.
Journal of insect physiology.
2007 Oct; 53(10):1072-8. doi:
10.1016/j.jinsphys.2007.06.006. [PMID: 17675053] - Constance Temm, Jesus H Dominguez. Microcirculation: nexus of comorbidities in diabetes.
American journal of physiology. Renal physiology.
2007 Aug; 293(2):F486-93. doi:
10.1152/ajprenal.00503.2006. [PMID: 17494088] - A Pál, D Méhn, E Molnár, S Gedey, P Mészáros, T Nagy, H Glavinas, T Janáky, O von Richter, G Báthori, L Szente, P Krajcsi. Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2.
The Journal of pharmacology and experimental therapeutics.
2007 Jun; 321(3):1085-94. doi:
10.1124/jpet.106.119289. [PMID: 17347325] - Jing-Xian Xu, Eiichi Morii, Yalan Liu, Naoto Nakamichi, Jun-Ichiro Ikeda, Hayato Kimura, Katsuyuki Aozasa. High tolerance to apoptotic stimuli induced by serum depletion and ceramide in side-population cells: high expression of CD55 as a novel character for side-population.
Experimental cell research.
2007 May; 313(9):1877-85. doi:
10.1016/j.yexcr.2007.03.006. [PMID: 17428472] - Shanmiao Gou, Tao Liu, Chunyou Wang, Tao Yin, Kai Li, Ming Yang, Jing Zhou. Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties.
Pancreas.
2007 May; 34(4):429-35. doi:
10.1097/mpa.0b013e318033f9f4. [PMID: 17446842] - Yang-ja Lee, Shin-ichi Miyake, Hideaki Wakita, David C McMullen, Yoshiaki Azuma, Sungyoung Auh, John M Hallenbeck. Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2007 May; 27(5):950-62. doi:
10.1038/sj.jcbfm.9600395. [PMID: 16955077] - Xuesheng Zheng, Gang Shen, Xiaofeng Yang, Weiguo Liu. Most C6 cells are cancer stem cells: evidence from clonal and population analyses.
Cancer research.
2007 Apr; 67(8):3691-7. doi:
10.1158/0008-5472.can-06-3912. [PMID: 17440081] - Yan-Nian Jiang, Yi-Hung Li, Meng-Wei Ke, Ting-Yu Tseng, Yueh-Bih Tang, Mu-Chiou Huang, Winston Teng-Kuei Cheng, Yu-Ten Ju. Caveolin-1 sensitizes rat pituitary adenoma GH3 cells to bromocriptine induced apoptosis.
Cancer cell international.
2007 Mar; 7(?):1. doi:
10.1186/1475-2867-7-1. [PMID: 17331262] - Oleg Tsinkalovsky, Audun Osland Vik-Mo, Sara Ferreira, Ole Didrik Laerum, Anders Fjose. Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties.
Differentiation; research in biological diversity.
2007 Mar; 75(3):175-83. doi:
10.1111/j.1432-0436.2006.00130.x. [PMID: 17288542] - Vishal Chanana, Siddharth Majumdar, Praveen Rishi. Involvement of caspase-3, lipid peroxidation and TNF-alpha in causing apoptosis of macrophages by coordinately expressed Salmonella phenotype under stress conditions.
Molecular immunology.
2007 Mar; 44(7):1551-8. doi:
10.1016/j.molimm.2006.08.022. [PMID: 17027970] - Isao Kobayashi, Tadaaki Moritomo, Mituru Ototake, Teruyuki Nakanishi. Isolation of side population cells from ginbuna carp (Carassius auratus langsdorfii) kidney hematopoietic tissues.
Developmental and comparative immunology.
2007; 31(7):696-707. doi:
10.1016/j.dci.2006.10.003. [PMID: 17129605]
