1,3-DIMETHYLUREA (BioDeep_00001871833)

Main id: BioDeep_00000011140

 


代谢物信息卡片


1,3-DIMETHYLUREA

化学式: C3H8N2O (88.0637)
中文名称: N,N-二甲基脲, 1,3-二甲基脲
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CNC(=O)NC
InChI: InChI=1S/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)

描述信息

同义名列表

4 个代谢物同义名

1,3-DIMETHYLUREA; N,N-dimethylurea; N,N'-Dimethylurea; 1,3-Dimethylurea



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ALB, AXIN2, CAT, DMAP1, MYLK, PRKX
Peripheral membrane protein 1 ACHE
Endosome membrane 1 BACE1
Nucleus 6 ACHE, ALB, AXIN2, DMAP1, DNMT1, PRKX
cytosol 7 ALB, AVP, AXIN2, CAT, DMAP1, MB, MYLK
dendrite 2 AVP, BACE1
trans-Golgi network 1 BACE1
centrosome 2 ALB, AXIN2
nucleoplasm 4 ATP2B1, DMAP1, DNMT1, PRKX
Cell membrane 5 ACHE, ATP2B1, BACE1, SLC14A2, SLC38A5
Cleavage furrow 1 MYLK
lamellipodium 1 MYLK
Cell projection, axon 1 BACE1
Multi-pass membrane protein 4 ATP2B1, MT-CYB, SLC14A2, SLC38A5
Synapse 3 ACHE, ATP2B1, MYLK
cell surface 2 ACHE, BACE1
glutamatergic synapse 1 ATP2B1
Golgi apparatus 3 ACHE, ALB, BACE1
lysosomal membrane 1 GAA
mitochondrial inner membrane 1 MT-CYB
neuromuscular junction 1 ACHE
neuronal cell body 1 BACE1
presynaptic membrane 1 ATP2B1
synaptic vesicle 1 BACE1
Lysosome 2 BACE1, GAA
endosome 1 BACE1
plasma membrane 10 ACHE, ATP2B1, AXIN2, BACE1, BCHE, GAA, ME2, MYLK, SLC14A2, SLC38A5
synaptic vesicle membrane 1 ATP2B1
Membrane 9 ACHE, ATP2B1, BACE1, CAT, GAA, ME2, MT-CYB, SLC14A2, SLC38A5
apical plasma membrane 1 SLC14A2
axon 1 BACE1
basolateral plasma membrane 1 ATP2B1
extracellular exosome 5 ALB, ATP2B1, CAT, GAA, MB
Lysosome membrane 1 GAA
endoplasmic reticulum 2 ALB, BACE1
extracellular space 5 ACHE, ALB, AVP, BCHE, IL2
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 1 ACHE
mitochondrion 4 CAT, DNMT1, ME2, MT-CYB
protein-containing complex 2 ALB, CAT
intracellular membrane-bounded organelle 4 ATP2B1, CAT, GAA, ME2
pericentric heterochromatin 1 DNMT1
Single-pass type I membrane protein 1 BACE1
Secreted 7 ACHE, ALB, AVP, BCHE, GAA, IL2, PRB1
extracellular region 8 ACHE, ALB, AVP, BCHE, CAT, GAA, IL2, PRB1
Single-pass membrane protein 1 ME2
hippocampal mossy fiber to CA3 synapse 1 BACE1
Mitochondrion matrix 1 ME2
mitochondrial matrix 2 CAT, ME2
Extracellular side 1 ACHE
anchoring junction 1 ALB
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
multivesicular body 1 BACE1
actin cytoskeleton 1 MYLK
beta-catenin destruction complex 1 AXIN2
sarcoplasm 1 MB
Early endosome 1 BACE1
recycling endosome 1 BACE1
Cell projection, lamellipodium 1 MYLK
Mitochondrion inner membrane 1 MT-CYB
Membrane raft 1 BACE1
focal adhesion 1 CAT
Peroxisome 1 CAT
basement membrane 1 ACHE
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 AVP
lateral plasma membrane 1 ATP2B1
Late endosome 1 BACE1
ciliary basal body 1 ALB
cell projection 1 ATP2B1
centriole 1 ALB
Golgi apparatus, trans-Golgi network 1 BACE1
spindle pole 1 ALB
blood microparticle 2 ALB, BCHE
NuA4 histone acetyltransferase complex 1 DMAP1
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
Endomembrane system 1 BACE1
female germ cell nucleus 1 DNMT1
Cytoplasmic vesicle membrane 1 BACE1
Cell projection, dendrite 1 BACE1
tertiary granule membrane 1 GAA
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
replication fork 2 DMAP1, DNMT1
stress fiber 1 MYLK
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 3 ALB, BACE1, BCHE
platelet alpha granule lumen 1 ALB
azurophil granule membrane 1 GAA
immunological synapse 1 ATP2B1
neuronal dense core vesicle 1 AVP
nuclear envelope lumen 1 BCHE
clathrin-coated endocytic vesicle membrane 1 AVP
respiratory chain complex III 1 MT-CYB
Cytoplasm, cytoskeleton, stress fiber 1 MYLK
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
nucleosome 1 DMAP1
Swr1 complex 1 DMAP1
Cytoplasm, sarcoplasm 1 MB
catalase complex 1 CAT
autolysosome lumen 1 GAA
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE
ciliary transition fiber 1 ALB
Golgi-associated vesicle lumen 1 BACE1
[Isoform 1]: Apical cell membrane 1 SLC14A2


文献列表

  • Yuan-ye Zhu, Mi Zhou. [Investigation of the Interaction between 1,3-Dimethylurea and Solvent by Raman Methods]. Guang pu xue yu guang pu fen xi = Guang pu. 2015 May; 35(5):1258-61. doi: ". [PMID: 26415439]
  • Yishan Chen, Xulin Pan, He Yan, Ninghua Tan. Multiple hydrogen-bonding interactions between macrocyclic triurea and F-, Cl-, Br-, I- and NO3(-): a theoretical investigation. Physical chemistry chemical physics : PCCP. 2011 Apr; 13(16):7384-95. doi: 10.1039/c0cp02749a. [PMID: 21423984]
  • D Collins, D C Winter, A M Hogan, L Schirmer, A W Baird, G S Stewart. Differential protein abundance and function of UT-B urea transporters in human colon. American journal of physiology. Gastrointestinal and liver physiology. 2010 Mar; 298(3):G345-51. doi: 10.1152/ajpgi.00405.2009. [PMID: 19926813]
  • Elena J Levin, Matthias Quick, Ming Zhou. Crystal structure of a bacterial homologue of the kidney urea transporter. Nature. 2009 Dec; 462(7274):757-61. doi: 10.1038/nature08558. [PMID: 19865084]
  • Geeta Godara, Craig Smith, Janine Bosse, Mark Zeidel, John Mathai. Functional characterization of Actinobacillus pleuropneumoniae urea transport protein, ApUT. American journal of physiology. Regulatory, integrative and comparative physiology. 2009 Apr; 296(4):R1268-73. doi: 10.1152/ajpregu.90726.2008. [PMID: 19144751]
  • Bryce Maciver, Craig P Smith, Warren G Hill, Mark L Zeidel. Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes. American journal of physiology. Renal physiology. 2008 Apr; 294(4):F956-64. doi: 10.1152/ajprenal.00229.2007. [PMID: 18256317]
  • Dan Zhao, N D Sonawane, Marc H Levin, Baoxue Yang. Comparative transport efficiencies of urea analogues through urea transporter UT-B. Biochimica et biophysica acta. 2007 Jul; 1768(7):1815-21. doi: 10.1016/j.bbamem.2007.04.010. [PMID: 17506977]
  • Gavin S Stewart, Sarah L King, Elizabeth A Potter, Craig P Smith. Acute regulation of mUT-A3 urea transporter expressed in a MDCK cell line. American journal of physiology. Renal physiology. 2007 Apr; 292(4):F1157-63. doi: 10.1152/ajprenal.00183.2006. [PMID: 17148784]
  • Otto Fröhlich, Janet D Klein, Pauline M Smith, Jeff M Sands, Robert B Gunn. Urea transport in MDCK cells that are stably transfected with UT-A1. American journal of physiology. Cell physiology. 2004 Jun; 286(6):C1264-70. doi: 10.1152/ajpcell.00499.2003. [PMID: 14749217]
  • Ben-Zhan Zhu, William E Antholine, Balz Frei. Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex. Free radical biology & medicine. 2002 Jun; 32(12):1333-8. doi: 10.1016/s0891-5849(02)00847-x. [PMID: 12057771]
  • Ying Feng, Zhi Wu Yu, Peter J Quinn. Effect of urea, dimethylurea, and tetramethylurea on the phase behavior of dioleoylphosphatidylethanolamine. Chemistry and physics of lipids. 2002 Feb; 114(2):149-57. doi: 10.1016/s0009-3084(01)00198-0. [PMID: 11934396]
  • T Klein, K Neuhaus, F Reutter, R M Nüsing. Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism. British journal of pharmacology. 2001 Jul; 133(5):643-50. doi: 10.1038/sj.bjp.0704111. [PMID: 11429387]
  • M A Trush, E G Mimnaugh, E Ginsburg, T E Gram. In vitro stimulation by paraquat of reactive oxygen-mediated lipid peroxidation in rat lung microsomes. Toxicology and applied pharmacology. 1981 Sep; 60(2):279-86. doi: 10.1016/0041-008x(91)90231-3. [PMID: 7281188]