Dimethylurea (BioDeep_00000011140)

 

Secondary id: BioDeep_00000172322, BioDeep_00001871833

human metabolite Endogenous Volatile Flavor Compounds


代谢物信息卡片


N,N-Dimethyl-urea

化学式: C3H8N2O (88.06365980000001)
中文名称: N,N-二甲基脲, 1,3-二甲基脲
谱图信息: 最多检出来源 Homo sapiens(lipidsearch) 5.66%

分子结构信息

SMILES: CN=C(O)NC
InChI: InChI=1S/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)

描述信息

Dimethylurea (DMU) (IUPAC systematic name: 1,3-Dimethylurea ) is a urea derivative and used as an intermediate in organic synthesis. It is a colorless crystalline powder with little toxicity.

同义名列表

6 个代谢物同义名

N,N-Dimethyl-urea; 1,3-DIMETHYLUREA; N,N-dimethylurea; Dimethylurea; N,N'-Dimethylurea; 1,3-Dimethylurea



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuan-ye Zhu, Mi Zhou. [Investigation of the Interaction between 1,3-Dimethylurea and Solvent by Raman Methods]. Guang pu xue yu guang pu fen xi = Guang pu. 2015 May; 35(5):1258-61. doi: ". [PMID: 26415439]
  • Yishan Chen, Xulin Pan, He Yan, Ninghua Tan. Multiple hydrogen-bonding interactions between macrocyclic triurea and F-, Cl-, Br-, I- and NO3(-): a theoretical investigation. Physical chemistry chemical physics : PCCP. 2011 Apr; 13(16):7384-95. doi: 10.1039/c0cp02749a. [PMID: 21423984]
  • D Collins, D C Winter, A M Hogan, L Schirmer, A W Baird, G S Stewart. Differential protein abundance and function of UT-B urea transporters in human colon. American journal of physiology. Gastrointestinal and liver physiology. 2010 Mar; 298(3):G345-51. doi: 10.1152/ajpgi.00405.2009. [PMID: 19926813]
  • Elena J Levin, Matthias Quick, Ming Zhou. Crystal structure of a bacterial homologue of the kidney urea transporter. Nature. 2009 Dec; 462(7274):757-61. doi: 10.1038/nature08558. [PMID: 19865084]
  • Geeta Godara, Craig Smith, Janine Bosse, Mark Zeidel, John Mathai. Functional characterization of Actinobacillus pleuropneumoniae urea transport protein, ApUT. American journal of physiology. Regulatory, integrative and comparative physiology. 2009 Apr; 296(4):R1268-73. doi: 10.1152/ajpregu.90726.2008. [PMID: 19144751]
  • Bryce Maciver, Craig P Smith, Warren G Hill, Mark L Zeidel. Functional characterization of mouse urea transporters UT-A2 and UT-A3 expressed in purified Xenopus laevis oocyte plasma membranes. American journal of physiology. Renal physiology. 2008 Apr; 294(4):F956-64. doi: 10.1152/ajprenal.00229.2007. [PMID: 18256317]
  • Dan Zhao, N D Sonawane, Marc H Levin, Baoxue Yang. Comparative transport efficiencies of urea analogues through urea transporter UT-B. Biochimica et biophysica acta. 2007 Jul; 1768(7):1815-21. doi: 10.1016/j.bbamem.2007.04.010. [PMID: 17506977]
  • Gavin S Stewart, Sarah L King, Elizabeth A Potter, Craig P Smith. Acute regulation of mUT-A3 urea transporter expressed in a MDCK cell line. American journal of physiology. Renal physiology. 2007 Apr; 292(4):F1157-63. doi: 10.1152/ajprenal.00183.2006. [PMID: 17148784]
  • Otto Fröhlich, Janet D Klein, Pauline M Smith, Jeff M Sands, Robert B Gunn. Urea transport in MDCK cells that are stably transfected with UT-A1. American journal of physiology. Cell physiology. 2004 Jun; 286(6):C1264-70. doi: 10.1152/ajpcell.00499.2003. [PMID: 14749217]
  • Ben-Zhan Zhu, William E Antholine, Balz Frei. Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex. Free radical biology & medicine. 2002 Jun; 32(12):1333-8. doi: 10.1016/s0891-5849(02)00847-x. [PMID: 12057771]
  • Ying Feng, Zhi Wu Yu, Peter J Quinn. Effect of urea, dimethylurea, and tetramethylurea on the phase behavior of dioleoylphosphatidylethanolamine. Chemistry and physics of lipids. 2002 Feb; 114(2):149-57. doi: 10.1016/s0009-3084(01)00198-0. [PMID: 11934396]
  • T Klein, K Neuhaus, F Reutter, R M Nüsing. Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism. British journal of pharmacology. 2001 Jul; 133(5):643-50. doi: 10.1038/sj.bjp.0704111. [PMID: 11429387]
  • M A Trush, E G Mimnaugh, E Ginsburg, T E Gram. In vitro stimulation by paraquat of reactive oxygen-mediated lipid peroxidation in rat lung microsomes. Toxicology and applied pharmacology. 1981 Sep; 60(2):279-86. doi: 10.1016/0041-008x(91)90231-3. [PMID: 7281188]