Deoxyuridine-5-diphosphate (BioDeep_00001868826)

Main id: BioDeep_00000004161

 

PANOMIX_OTCML-2023


代谢物信息卡片


Deoxyuridine-5-diphosphate

化学式: C9H14N2O11P2 (388.0073)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(C(OC1N2C=CC(=O)NC2=O)COP(=O)(O)OP(=O)(O)O)O
InChI: InChI=1S/C9H14N2O11P2/c12-5-3-8(11-2-1-7(13)10-9(11)14)21-6(5)4-20-24(18,19)22-23(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1

描述信息

同义名列表

2 个代谢物同义名

Deoxyuridine-5-diphosphate; dUDP



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 ANXA5, CASP3, CMPK2, DCTD, DHFR, DTYMK, KITLG, MAPK14, PIK3CA, PKM, TYMS, VEGFA
Peripheral membrane protein 1 ANXA5
Endoplasmic reticulum membrane 1 RTN4
Nucleus 10 CASP3, DTYMK, DUT, FASLG, MAPK14, PARP1, PCNA, PKM, TYMS, VEGFA
cytosol 10 ANXA5, CASP3, DCTD, DHFR, DTYMK, MAPK14, PARP1, PIK3CA, PKM, TYMS
nuclear body 2 PARP1, PCNA
centrosome 1 PCNA
nucleoplasm 6 CASP3, CMPK2, DUT, MAPK14, PARP1, PCNA
Cell membrane 5 AQP5, FASLG, KITLG, RTN4, TNF
Cytoplasmic side 1 RTN4
lamellipodium 2 KITLG, PIK3CA
Multi-pass membrane protein 2 AQP5, RTN4
Synapse 1 RTN4
cell junction 1 RTN4
cell surface 2 TNF, VEGFA
glutamatergic synapse 3 CASP3, MAPK14, RTN4
Golgi apparatus 1 VEGFA
mitochondrial inner membrane 1 TYMS
neuronal cell body 3 CASP3, RTN4, TNF
sarcolemma 1 ANXA5
Cytoplasm, cytosol 1 PARP1
plasma membrane 6 AQP5, FASLG, KITLG, PIK3CA, RTN4, TNF
Membrane 5 ANXA5, FASLG, KITLG, PARP1, VEGFA
apical plasma membrane 1 AQP5
caveola 1 FASLG
extracellular exosome 6 ANXA5, AQP5, DUT, FASLG, PCNA, PKM
endoplasmic reticulum 3 AQP5, RTN4, VEGFA
extracellular space 5 AMH, FASLG, KITLG, TNF, VEGFA
lysosomal lumen 1 FASLG
perinuclear region of cytoplasm 2 FASLG, PIK3CA
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
mitochondrion 8 CMPK2, DHFR, DTYMK, DUT, MAPK14, PARP1, PKM, TYMS
protein-containing complex 1 PARP1
filopodium 1 KITLG
postsynaptic density 2 CASP3, RTN4
Single-pass type I membrane protein 1 KITLG
Secreted 4 AMH, FASLG, KITLG, VEGFA
extracellular region 8 AMH, ANXA5, FASLG, KITLG, MAPK14, PKM, TNF, VEGFA
Mitochondrion matrix 1 TYMS
mitochondrial matrix 2 DTYMK, TYMS
Extracellular side 1 RTN4
Cytoplasmic vesicle lumen 1 FASLG
anchoring junction 1 RTN4
transcription regulator complex 1 PARP1
external side of plasma membrane 3 ANXA5, FASLG, TNF
Extracellular vesicle 1 PKM
Secreted, extracellular space, extracellular matrix 1 VEGFA
nucleolus 1 PARP1
recycling endosome 1 TNF
Single-pass type II membrane protein 2 FASLG, TNF
vesicle 1 PKM
Apical cell membrane 1 AQP5
Cell projection, lamellipodium 1 KITLG
Mitochondrion inner membrane 1 TYMS
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 KITLG
focal adhesion 1 ANXA5
extracellular matrix 1 VEGFA
collagen-containing extracellular matrix 2 ANXA5, PKM
secretory granule 1 VEGFA
nuclear speck 1 MAPK14
Cell projection, filopodium 1 KITLG
Zymogen granule membrane 1 ANXA5
neuron projection 1 RTN4
cilium 1 PKM
chromatin 2 PARP1, PCNA
phagocytic cup 1 TNF
Chromosome 1 PARP1
cytoskeleton 1 KITLG
Nucleus, nucleolus 1 PARP1
spindle pole 1 MAPK14
nuclear replication fork 2 PARP1, PCNA
chromosome, telomeric region 2 PARP1, PCNA
site of double-strand break 1 PARP1
nuclear envelope 2 PARP1, RTN4
microvillus 1 AQP5
Cytoplasmic vesicle membrane 1 AQP5
replication fork 1 PCNA
basal plasma membrane 1 AQP5
ficolin-1-rich granule lumen 2 MAPK14, PKM
secretory granule lumen 2 MAPK14, PKM
male germ cell nucleus 1 PCNA
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
Lysosome lumen 1 FASLG
[Isoform 2]: Cytoplasm 1 KITLG
vesicle membrane 1 ANXA5
nuclear lamina 1 PCNA
[Isoform 2]: Nucleus 1 DUT
protein-DNA complex 1 PARP1
death-inducing signaling complex 1 CASP3
Rough endoplasmic reticulum 1 PKM
[Isoform 3]: Mitochondrion 1 DUT
site of DNA damage 1 PARP1
cyclin-dependent protein kinase holoenzyme complex 1 PCNA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
endothelial microparticle 1 ANXA5
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
PCNA complex 1 PCNA
PCNA-p21 complex 1 PCNA
replisome 1 PCNA
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[Tumor necrosis factor ligand superfamily member 6, soluble form]: Secreted 1 FASLG
[FasL intracellular domain]: Nucleus 1 FASLG
endoplasmic reticulum tubular network 1 RTN4
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
endoplasmic reticulum tubular network membrane 1 RTN4
[Isoform a]: Endoplasmic reticulum membrane 1 RTN4
[Isoform b]: Endoplasmic reticulum membrane 1 RTN4
[Isoform C]: Endoplasmic reticulum membrane 1 RTN4


文献列表

  • Hiroshi Maruoka, Matthew O Barrett, Hyojin Ko, Dilip K Tosh, Artem Melman, Lauren E Burianek, Ramachandran Balasubramanian, Barkin Berk, Stefano Costanzi, T Kendall Harden, Kenneth A Jacobson. Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications. Journal of medicinal chemistry. 2010 Jun; 53(11):4488-501. doi: 10.1021/jm100287t. [PMID: 20446735]
  • Pedro Besada, Dae Hong Shin, Stefano Costanzi, Hyojin Ko, Christophe Mathé, Julien Gagneron, Gilles Gosselin, Savitri Maddileti, T Kendall Harden, Kenneth A Jacobson. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. Journal of medicinal chemistry. 2006 Sep; 49(18):5532-43. doi: 10.1021/jm060485n. [PMID: 16942026]