p-chloromercuribenzoic acid (BioDeep_00001868473)
Main id: BioDeep_00000005209
代谢物信息卡片
p-chloromercuribenzoic acid
化学式: C7H5ClHgO2 (357.9684)
中文名称: 对氯汞苯甲酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C(=O)O)[Hg]Cl
InChI: /q
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D013439 - Sulfhydryl Reagents
D010575 - Pesticides > D005659 - Fungicides, Industrial > D010663 - Phenylmercury Compounds
D004791 - Enzyme Inhibitors > D002729 - Chloromercuribenzoates
D004791 - Enzyme Inhibitors > D008626 - Mercuribenzoates
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:28420
- KEGG: C03444
- PubChem: 1730
- MeSH: p-Chloromercuribenzoic Acid
- CAS: 59-85-8
- PubChem: 6268
- PDB-CCD: BE7
- NIKKAJI: J36.999C
- RefMet: p-Chloromercuribenzoic acid
- KNApSAcK: 28420
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Arijit Pal, Anusri Tripathi. Toxicological and behavioral study of two potential antibacterial agents:4-chloromercuribenzoic acid and quercetin on Swiss-albino mice.
Drug and chemical toxicology.
2020 Nov; 43(6):645-655. doi:
10.1080/01480545.2018.1517774. [PMID: 30394115] - Satoshi Endo, Airi Fujimoto, Sho Kumada, Toshiyuki Matsunaga, Satoshi Ohno, Jun'ichi Mano, Kazuo Tajima, Ossama El-Kabbani, Akira Hara. Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents.
Chemico-biological interactions.
2013 Feb; 202(1-3):146-52. doi:
10.1016/j.cbi.2012.11.026. [PMID: 23261715] - Mamoon Rashid, Thiruma V Arumugam, Vardan T Karamyan. Association of the novel non-AT1, non-AT2 angiotensin binding site with neuronal cell death.
The Journal of pharmacology and experimental therapeutics.
2010 Dec; 335(3):754-61. doi:
10.1124/jpet.110.171439. [PMID: 20861168] - Sandeep Kumar, Arvind M Kayastha. Soybean (Glycine max) urease: significance of sulfhydryl groups in urea catalysis.
Plant physiology and biochemistry : PPB.
2010 Sep; 48(9):746-50. doi:
10.1016/j.plaphy.2010.05.007. [PMID: 20558076] - Vardan T Karamyan, Florian Gembardt, Felicia M Rabey, Thomas Walther, Robert C Speth. Characterization of the brain-specific non-AT(1), non-AT(2) angiotensin binding site in the mouse.
European journal of pharmacology.
2008 Aug; 590(1-3):87-92. doi:
10.1016/j.ejphar.2008.05.035. [PMID: 18571643] - Qi Wang, Marilyn E Morris. The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells.
Drug metabolism and disposition: the biological fate of chemicals.
2007 Aug; 35(8):1393-9. doi:
10.1124/dmd.107.014852. [PMID: 17502341] - S V Osipova, A V Permyakov, T N Mitrofanova, L V Dudareva, V A Trufanov. Characteristics of thiol:protein disulfide oxidoreductase from wheat (Triticum aestivum L.) grain.
Biochemistry. Biokhimiia.
2005 Aug; 70(8):935-40. doi:
10.1007/s10541-005-0205-1. [PMID: 16212551] - Joseph M Weber, Angelique Ruzindana-Umunyana, Lise Imbeault, Sucheta Sircar. Inhibition of adenovirus infection and adenain by green tea catechins.
Antiviral research.
2003 Apr; 58(2):167-73. doi:
10.1016/s0166-3542(02)00212-7. [PMID: 12742577] - T Belyaeva, E Leontieva, A Shpakov, T Mozhenok, M Faddejeva. Sensitivity of lysosomal enzymes to the plant alkaloid sanguinarine: comparison with other SH-specific agents.
Cell biology international.
2003; 27(11):887-95. doi:
10.1016/s1065-6995(03)00161-6. [PMID: 14585282] - Tohru Tsuchiya, Takuo Suzuki, Takafumi Yamada, Hiroshi Shimada, Tatsuru Masuda, Hiroyuki Ohta, Ken-ichiro Takamiya. Chlorophyllase as a serine hydrolase: identification of a putative catalytic triad.
Plant & cell physiology.
2003 Jan; 44(1):96-101. doi:
10.1093/pcp/pcg011. [PMID: 12552153] - Kaisa Huhtinen, James O'Byrne, Per J G Lindquist, Juan A Contreras, Stefan E H Alexson. The peroxisome proliferator-induced cytosolic type I acyl-CoA thioesterase (CTE-I) is a serine-histidine-aspartic acid alpha /beta hydrolase.
The Journal of biological chemistry.
2002 Feb; 277(5):3424-32. doi:
10.1074/jbc.m109040200. [PMID: 11694534] - M F Rosenberg, G Velarde, R C Ford, C Martin, G Berridge, I D Kerr, R Callaghan, A Schmidlin, C Wooding, K J Linton, C F Higgins. Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle.
The EMBO journal.
2001 Oct; 20(20):5615-25. doi:
10.1093/emboj/20.20.5615. [PMID: 11598005] - N V Fedirko, V V Man'ko, M Iu Klevets'. [Effect of p-chloromercuribenzoic acid and dithiothreitol on the Ca(2+) content of salivary glands and their protein secretion].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
2001; 47(3):35-41. doi:
. [PMID: 11519248] - N V Fedirko, Kievets MYu, V V Manko. Modulation influence of p-chloromercuribenzoate on plasma membrane Na+-Ca2+ exchanger of the secretory cells of chironomus larvae salivary gland.
Advances in experimental medicine and biology.
2001; 500(?):467-70. doi:
10.1007/978-1-4615-0667-6_71. [PMID: 11764983] - E M Oliveira, R A Santos, J E Krieger. Standardization of a fluorimetric assay for the determination of tissue angiotensin-converting enzyme activity in rats.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2000 Jul; 33(7):755-64. doi:
10.1590/s0100-879x2000000700005. [PMID: 10881050] - Z Galewska, E Bańkowski, L Romanowicz, S Jaworski. EPH-gestosis (pre-eclampsia)-induced decrease of gelatinase activity may promote an accumulation of collagen in the umbilical cord artery.
European journal of obstetrics, gynecology, and reproductive biology.
2000 Feb; 88(2):189-95. doi:
10.1016/s0301-2115(99)00146-3. [PMID: 10690679] - T D Choudhury, N Das, A Chattopadhyay, A G Datta. Effect of oxidative stress and erythropoietin on cytoskeletal protein and lipid organization in human erythrocytes.
Polish journal of pharmacology.
1999 Jul; 51(4):341-50. doi:
. [PMID: 10540966] - V U Buko, A A Artsukevich, K V Ignatenko. Aldehydic products of lipid peroxidation inactivate cytochrome P-450.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
1999 Jul; 51(4-5):294-8. doi:
10.1016/s0940-2993(99)80009-8. [PMID: 10445385] - D Chevenne, A Letailleur, F Trivin, D Porquet. Effect of hemolysis on the concentration of insulin in serum determined by RIA and IRMA.
Clinical chemistry.
1998 Feb; 44(2):354-6. doi:
10.1093/clinchem/44.2.354. [PMID: 9474041] - H Maeda, T Okamoto, T Akaike. Human matrix metalloprotease activation by insults of bacterial infection involving proteases and free radicals.
Biological chemistry.
1998 Feb; 379(2):193-200. doi:
10.1515/bchm.1998.379.2.193. [PMID: 9524071] - W M Cai, P Z Guan, W Zhao, J Yin, C K Fei. [Identification of gravity-related esterases (grEST1 and grEST2) in carrot callus cells].
Zhi wu sheng li xue bao = Acta phytophysiologica Sinica.
1998; 24(4):392-8. doi:
". [PMID: 11543433] - D F Cunningham, B O'Connor. A study of prolyl endopeptidase in bovine serum and its relevance to the tissue enzyme.
The international journal of biochemistry & cell biology.
1998 Jan; 30(1):99-114. doi:
10.1016/s1357-2725(97)00076-9. [PMID: 9597757] - J M Granjeiro, C V Ferreira, M B Jucá, E M Taga, H Aoyama. Bovine kidney low molecular weight acid phosphatase: FMN-dependent kinetics.
Biochemistry and molecular biology international.
1997 May; 41(6):1201-8. doi:
10.1080/15216549700202291. [PMID: 9161715] - E Hadas, T Mazur. Biosynthesis of prostaglandins in pathogenic and nonpathogenic strains of Acanthamoeba spp.
Parasitology research.
1997; 83(3):296-9. doi:
10.1007/s004360050250. [PMID: 9089729] - N Hilaire, R Salvayre, J C Thiers, M J Bonnafé, A Nègre-Salvayre. The turnover of cytoplasmic triacylglycerols in human fibroblasts involves two separate acyl chain length-dependent degradation pathways.
The Journal of biological chemistry.
1995 Nov; 270(45):27027-34. doi:
10.1074/jbc.270.45.27027. [PMID: 7592952] - I Petcu, M Lupu, R Grosescu. NMR study of the selective inhibition of water permeability of rat erythrocyte membrane.
Bioscience reports.
1995 Feb; 15(1):55-63. doi:
10.1007/bf01200215. [PMID: 7647292] - D J Morré, D M Morré. Differential response of the NADH oxidase of plasma membranes of rat liver and hepatoma and HeLa cells to thiol reagents.
Journal of bioenergetics and biomembranes.
1995 Feb; 27(1):137-44. doi:
10.1007/bf02110341. [PMID: 7629045] - E W Morgan, B Yan, D Greenway, D R Petersen, A Parkinson. Purification and characterization of two rat liver microsomal carboxylesterases (hydrolase A and B).
Archives of biochemistry and biophysics.
1994 Dec; 315(2):495-512. doi:
10.1006/abbi.1994.1531. [PMID: 7986098] - B Mikami, K Nomura, Y Morita. Two sulfhydryl groups near the active site of soybean beta-amylase.
Bioscience, biotechnology, and biochemistry.
1994 Jan; 58(1):126-32. doi:
10.1271/bbb.58.126. [PMID: 7764509] - A V Kulikov, F T Umarova, G I Likhtenshteĭn. [Interaction of spin labels and probes with Na+,K+-ATPase].
Ukrainskii biokhimicheskii zhurnal (1978).
1993 May; 65(3):38-45. doi:
. [PMID: 8291140] - J Sakurai, Y Fujii, M Nagahama. Effect of p-chloromercuribenzoate on Clostridium perfringens beta toxin.
Toxicon : official journal of the International Society on Toxinology.
1992 Mar; 30(3):323-30. doi:
10.1016/0041-0101(92)90872-3. [PMID: 1529464] - K Kohara, Y Tabuchi, P Senanayake, K B Brosnihan, C M Ferrario. Reassessment of plasma angiotensins measurement: effects of protease inhibitors and sample handling procedures.
Peptides.
1991 Sep; 12(5):1135-41. doi:
10.1016/0196-9781(91)90070-6. [PMID: 1666184] - M Loghman-Adham. Characterization of essential sulfhydryl groups of rat renal Na(+)-Pi cotransporter.
The American journal of physiology.
1991 Jun; 260(6 Pt 2):F874-82. doi:
10.1152/ajprenal.1991.260.6.f874. [PMID: 1647689] - H T Sun, Y Yoshida, S Imai. A Ca2(+)-activated, Mg2(+)-dependent ATPase with high affinities for both Ca2+ and Mg2+ in vascular smooth muscle microsomes: comparison with plasma membrane Ca2(+)-pump ATPase.
Journal of biochemistry.
1990 Nov; 108(5):730-6. doi:
10.1093/oxfordjournals.jbchem.a123273. [PMID: 1964453] - Z Schwartz, L D Swain, V Ramirez, B D Boyan. Regulation of arachidonic acid turnover by 1,25-(OH)2D3 and 24,25-(OH)2D3 in growth zone and resting zone chondrocyte cultures.
Biochimica et biophysica acta.
1990 Sep; 1027(3):278-86. doi:
10.1016/0005-2736(90)90319-j. [PMID: 2397237] - P Hopmeier, M Halbmayer, M Fischer, G Marx. Zinc modulates thrombin adsorption to fibrin.
Thrombosis research.
1990 May; 58(3):293-301. doi:
10.1016/0049-3848(90)90099-x. [PMID: 2353341] - L P Karniski. Activation of Cl-/OH- exchange by parachloromercuribenzoic acid in rabbit renal brush-border membranes.
The Journal of membrane biology.
1989 Nov; 112(1):59-66. doi:
10.1007/bf01871164. [PMID: 2593140] - B Stahl, H Wiesinger, B Hamprecht. Characteristics of sorbitol uptake in rat glial primary cultures.
Journal of neurochemistry.
1989 Sep; 53(3):665-71. doi:
10.1111/j.1471-4159.1989.tb11755.x. [PMID: 2760614] - J C Barton. Retention of radiolead by human erythrocytes in vitro.
Toxicology and applied pharmacology.
1989 Jun; 99(2):314-22. doi:
10.1016/0041-008x(89)90013-6. [PMID: 2734794] - W T Forsee, C F Palmer, J S Schutzbach. Purification and characterization of an alpha-1,2-mannosidase involved in processing asparagine-linked oligosaccharides.
The Journal of biological chemistry.
1989 Mar; 264(7):3869-76. doi:
. [PMID: 2917980] - J Chauhan, K Dakshinamurti. Role of human serum biotinidase as biotin-binding protein.
The Biochemical journal.
1988 Nov; 256(1):265-70. doi:
10.1042/bj2560265. [PMID: 3223902] - K Alizadeh-Khiavi, Z Ali-Khan. Biochemical nature and cellular origin of amyloid enhancing factor (AEF) as determined by anti-AEF antibody.
British journal of experimental pathology.
1988 Oct; 69(5):605-19. doi:
NULL. [PMID: 3058197] - A Galvan, C F Louis. Calcium regulation by lens plasma membrane vesicles.
Archives of biochemistry and biophysics.
1988 Aug; 264(2):472-81. doi:
10.1016/0003-9861(88)90312-8. [PMID: 2840857] - B Allinquant, C Musenger, J Reboul, J J Hauw, E Schuller. Specific RNase isoenzymes in the human central nervous system.
Neurochemical research.
1987 Dec; 12(12):1067-76. doi:
10.1007/bf00971706. [PMID: 3441268] - A S Vallari, R M Macleod, H M Jernigan. Rat lens glutaminase: separation and characterization of soluble and particulate fractions.
Experimental eye research.
1987 Oct; 45(4):491-500. doi:
10.1016/s0014-4835(87)80060-x. [PMID: 3428382] - T H Duffy, S B Beckman, S M Peterson, K S Vitols, F M Huennekens. L1210 dihydrofolate reductase. Kinetics and mechanism of activation by various agents.
The Journal of biological chemistry.
1987 May; 262(15):7028-33. doi:
10.1016/s0021-9258(18)48197-5. [PMID: 3294825] - M Verma. Purification and properties of RNA polymerase of phage KB1.
Biochemistry international.
1986 Jun; 12(6):921-31. doi:
NULL. [PMID: 3527171] - C Durieux, B Charpentier, D Pelaprat, B P Roques. Investigation on the metabolism of CCK8 analogues by rat brain slices.
Neuropeptides.
1986 Jan; 7(1):1-9. doi:
10.1016/0143-4179(86)90072-7. [PMID: 3456492] - S Sh Suleĭmanov, Iu P Denisov, P V Sergeev. [Nature of the recognition system of uterine cell plasma membranes for estradiol].
Farmakologiia i toksikologiia.
1985 Nov; 48(6):58-61. doi:
NULL. [PMID: 4085633] - Y Kono, M Wada, Y Namiki. [Properties of sodium- and potassium-dependent adenosine triphosphatase in the plasma membrane of albino rabbit dental pulp].
Nichidai koku kagaku = Nihon University journal of oral science.
1985 Sep; 11(3):220-30. doi:
NULL. [PMID: 3003567] - J M Hanley, E C Heath. A novel proteolytic activity in serum processes rat prohaptoglobin.
Archives of biochemistry and biophysics.
1985 Jun; 239(2):404-19. doi:
10.1016/0003-9861(85)90706-4. [PMID: 3923935] - M Barua, U Bhattacharyya, G C Majumder. Occurrence of an ecto-phosphoprotein phosphatase in goat epididymal spermatozoa.
Biochemistry international.
1985 May; 10(5):733-41. doi:
NULL. [PMID: 2990477] - G J Jones, T D Waite, J D Smith. Light-dependent reduction of copper(II) and its effect on cell-mediated, thiol-dependent superoxide production.
Biochemical and biophysical research communications.
1985 Apr; 128(2):1031-6. doi:
10.1016/0006-291x(85)90151-2. [PMID: 2986618] - E L Thomas, M B Grisham, D F Melton, M M Jefferson. Evidence for a role of taurine in the in vitro oxidative toxicity of neutrophils toward erythrocytes.
The Journal of biological chemistry.
1985 Mar; 260(6):3321-9. doi:
10.1016/s0021-9258(19)83623-2. [PMID: 3972827] - M Cucuianu, T Fekete, C Marcusiu, R Mösler, A Duţu. Fibrinolysis in diabetes mellitus. Role of overweight and hypertriglyceridemia.
Medecine interne.
1984 Jul; 22(3):171-7. doi:
NULL. [PMID: 6494764] - S A Hunter, S Burstein, C Sedor. Stimulation of prostaglandin synthesis in WI-38 human lung fibroblasts following inhibition of phospholipid acylation by p-hydroxymercuribenzoate.
Biochimica et biophysica acta.
1984 Apr; 793(2):202-12. doi:
10.1016/0005-2760(84)90322-9. [PMID: 6324869] - F Le Gaillard, H Azam, G Favre, M Dautrevaux. Reversible dissociation of cortisol-transcortin complex by sodium para-chloromercuribenzoate.
Biochimica et biophysica acta.
1983 Dec; 749(3):289-95. doi:
10.1016/0167-4838(83)90238-8. [PMID: 6419776] - E C Foulkes. Nature of inhibition of renal aspartate reabsorption in experimental Fanconi syndrome.
Toxicology and applied pharmacology.
1983 Dec; 71(3):445-50. doi:
10.1016/0041-008x(83)90033-9. [PMID: 6658792] - K Gwoździński, G Bartosz, W Leyko. Effect of thiol reagents and ionizing radiation on the permeability of erythrocyte membrane for spin-labeled non-electrolytes.
Radiation and environmental biophysics.
1983; 22(1):53-9. doi:
10.1007/bf01323760. [PMID: 6225140] - Y Mizukami, F Matsubara, S Matsukawa, R Izumi. Cytochemical localization of glutaraldehyde-resistant NAD(P)H-oxidase in rat hepatocytes.
Histochemistry.
1983; 79(2):259-67. doi:
10.1007/bf00489788. [PMID: 6196337] - J J Hjelle, J H Grubbs, D R Petersen. Inhibition of mitochondrial aldehyde dehydrogenase by malondialdehyde.
Toxicology letters.
1982 Nov; 14(1-2):35-43. doi:
10.1016/0378-4274(82)90007-8. [PMID: 7157414] - T A Palladina, N V Petrova. [The role of SH-groups in the development sensitivity of ATPase in plasma membranes of plant cells to ions].
Biokhimiia (Moscow, Russia).
1982 Jul; 47(7):1154-8. doi:
NULL. [PMID: 6214285] - K Hartmann, C Voss, G Hübner, N Hartmann. [Effectors and products of enzymatic diiodotyrosine deiodination by a plasmatic fraction from pig liver].
Acta biologica et medica Germanica.
1981; 40(3):265-74. doi:
. [PMID: 7304042] - Iu P Denisov, P V Sergeev, N P Saksonov, G V Shutko. [Characteristics of the steroid hormone binding system in hepatocyte plasma membranes].
Biulleten' eksperimental'noi biologii i meditsiny.
1980 Feb; 89(2):172-4. doi:
NULL. [PMID: 7370416] - A Loyter, A Lalazar. Induction of membrane fusion in human erythrocyte ghosts: involvement of spectrin in the fusion process.
Society of General Physiologists series.
1980; 34(?):11-26. doi:
". [PMID: 6155704] - B A Woda, D M Knowles. Nodular lymphocytic lymphoma eventuating into diffuse histiocytic lymphoma: immunoperoxidase demonstration of monoclonality.
Cancer.
1979 Jan; 43(1):303-7. doi:
10.1002/1097-0142(197901)43:1<303::aid-cncr2820430144>3.0.co;2-y. [PMID: 104787]
