DIBUTYL SUCCINATE (BioDeep_00001868075)

Main id: BioDeep_00000001777

 


代谢物信息卡片


DIBUTYL SUCCINATE

化学式: C12H22O4 (230.1518)
中文名称: 丁二酸二丁酯, 琥珀酸二丁酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCOC(=O)CCC(=O)OCCCC
InChI: InChI=1S/C12H22O4/c1-3-5-9-15-11(13)7-8-12(14)16-10-6-4-2/h3-10H2,1-2H3

描述信息

P - Antiparasitic products, insecticides and repellents > P03 - Ectoparasiticides, incl. scabicides, insecticides and repellents > P03B - Insecticides and repellents

同义名列表

3 个代谢物同义名

DIBUTYL SUCCINATE; Dibutyl succinate; Dibutyl succinate



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 BCL2, MAPK14, MARVELD1, NLRP3, S100B, TJP1, TLR4
Peripheral membrane protein 1 TJP1
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 2 BCL2, CD4
Nucleus 8 BCL2, MAPK14, MARVELD1, MPO, NLRP3, S100B, TBX21, TJP1
cytosol 5 BCL2, MAPK14, NLRP3, S100B, TJP1
nucleoplasm 3 MAPK14, MPO, S100B
Cell membrane 6 CD4, MARVELD1, SELP, TJP1, TLR4, TNF
Cytoplasmic side 1 TJP1
Multi-pass membrane protein 1 MARVELD1
Golgi apparatus membrane 1 NLRP3
cell junction 1 TJP1
cell surface 2 TLR4, TNF
glutamatergic synapse 1 MAPK14
Golgi membrane 1 NLRP3
neuronal cell body 3 S100B, TBX21, TNF
Cytoplasm, cytosol 1 NLRP3
Lysosome 1 MPO
plasma membrane 8 CD4, IFNLR1, MARVELD1, MUC2, SELP, TJP1, TLR4, TNF
Membrane 5 BCL2, IFNLR1, MARVELD1, NLRP3, TLR4
apical plasma membrane 1 TJP1
basolateral plasma membrane 1 TJP1
extracellular exosome 2 MPO, SELP
endoplasmic reticulum 2 BCL2, NLRP3
extracellular space 11 CCL2, CXCL8, IL10, IL17A, IL2, IL6, MPO, MUC2, S100B, SELP, TNF
perinuclear region of cytoplasm 2 S100B, TLR4
Cell junction, tight junction 1 TJP1
adherens junction 1 TJP1
apicolateral plasma membrane 1 TJP1
bicellular tight junction 1 TJP1
gap junction 1 TJP1
intercalated disc 1 TJP1
intercellular canaliculus 1 TJP1
mitochondrion 4 BCL2, MAPK14, NLRP3, TJP1
protein-containing complex 2 BCL2, TJP1
intracellular membrane-bounded organelle 2 MPO, S100B
Single-pass type I membrane protein 4 CD4, IFNLR1, SELP, TLR4
Secreted 10 CCL2, CXCL8, IL10, IL17A, IL2, IL6, MUC2, NLRP3, S100B, SELP
extracellular region 13 CCL2, CXCL8, IL10, IL17A, IL2, IL6, MAPK14, MPO, MUC2, NLRP3, S100B, SELP, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 5 CD4, IL17A, SELP, TLR4, TNF
Early endosome 2 CD4, TLR4
apical part of cell 1 TJP1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 CD4, TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 MARVELD1
extracellular matrix 1 MUC2
collagen-containing extracellular matrix 1 MUC2
secretory granule 1 MPO
nuclear speck 1 MAPK14
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Cell projection, ruffle 1 TLR4
ruffle 2 S100B, TLR4
receptor complex 1 TLR4
chromatin 1 TBX21
cell projection 1 TJP1
phagocytic cup 2 TLR4, TNF
cytoskeleton 1 MARVELD1
Cell projection, podosome 1 TJP1
podosome 1 TJP1
spindle pole 1 MAPK14
Endomembrane system 1 NLRP3
microtubule organizing center 1 NLRP3
myelin sheath 1 BCL2
azurophil granule 1 MPO
platelet dense granule membrane 1 SELP
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
Golgi lumen 1 MUC2
endoplasmic reticulum lumen 2 CD4, IL6
tight junction 1 TJP1
azurophil granule lumen 1 MPO
clathrin-coated endocytic vesicle membrane 1 CD4
phagocytic vesicle lumen 1 MPO
apical junction complex 1 TJP1
platelet alpha granule membrane 1 SELP
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
platelet dense granule lumen 1 SELP
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
inner mucus layer 1 MUC2
outer mucus layer 1 MUC2
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Valéria Costa Da Silva, Gerlane Coelho Bernardo Guerra, Daline Fernandes De Souza Araújo, Edilane Rodrigues De Araújo, Aurigena Antunes De Araújo, Renato Dantas-Medeiros, Ana Caroline Zanatta, Isadora Luisa Gomes Da Silva, Raimundo Fernandes De Araújo Júnior, Debora Esposito, Marvin Moncada, Silvana Maria Zucolotto. Chemopreventive and immunomodulatory effects of phenolic-rich extract of Commiphora leptophloeos against inflammatory bowel disease: Preclinical evidence. Journal of ethnopharmacology. 2024 Jun; 328(?):118025. doi: 10.1016/j.jep.2024.118025. [PMID: 38458342]
  • Stefania Lama, Ester Pagano, Francesca Borrelli, Maria Maisto, Gian Carlo Tenore, Maria Francesca Nanì, Pilar Chacon-Millan, Ettore Novellino, Paola Stiuso. Polyphenol-Rich Extract from 'Limoncella' Apple Variety Ameliorates Dinitrobenzene Sulfonic Acid-Induced Colitis and Linked Liver Damage. International journal of molecular sciences. 2024 Mar; 25(6):. doi: 10.3390/ijms25063210. [PMID: 38542183]
  • Tommaso Venneri, Giada Giorgini, Nadine Leblanc, Nicolas Flamand, Francesca Borrelli, Cristoforo Silvestri, Vincenzo Di Marzo. Altered endocannabinoidome bioactive lipid levels accompany reduced DNBS-induced colonic inflammation in germ-free mice. Lipids in health and disease. 2023 May; 22(1):63. doi: 10.1186/s12944-023-01823-1. [PMID: 37189092]
  • José R Cruz-Muñoz, Tonatiuh Barrios-García, Eduardo E Valdez-Morales, María F Durán-Vazquez, Karen B Méndez-Rodríguez, Alma Barajas-Espinosa, Fernando Ochoa-Cortes, María C Martínez-Saldaña, Yenny A Gómez-Aguirre, Raquel Guerrero Alba. Ethanolic extract from Lepidium virginicum L. ameliorates DNBS-induced colitis in rats. Journal of ethnopharmacology. 2022 May; 289(?):115056. doi: 10.1016/j.jep.2022.115056. [PMID: 35104576]
  • Emiliano Manzo, Aniello Schiano Moriello, Francesco Tinto, Roberta Verde, Marco Allarà, Luciano De Petrocellis, Ester Pagano, Angelo A Izzo, Vincenzo Di Marzo, Stefania Petrosino. A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator. Cells. 2021 02; 10(2):. doi: 10.3390/cells10020450. [PMID: 33672574]
  • Carmen Parisio, Elena Lucarini, Laura Micheli, Alessandra Toti, Maria Bellumori, Lorenzo Cecchi, Laura Calosi, Daniele Bani, Lorenzo Di Cesare Mannelli, Nadia Mulinacci, Carla Ghelardini. Extra virgin olive oil and related by-products (Olea europaea L.) as natural sources of phenolic compounds for abdominal pain relief in gastrointestinal disorders in rats. Food & function. 2020 Dec; 11(12):10423-10435. doi: 10.1039/d0fo02293d. [PMID: 33237043]
  • Valéria Costa da Silva, Aurigena Antunes de Araújo, Daline Fernandes de Souza Araújo, Maíra Conceição Jerônimo Souza Lima, Roseane Carvalho Vasconcelos, Raimundo Fernandes de Araújo Júnior, Silvana Maria Zucolotto Langasnner, Matheus de Freitas Fernandes Pedrosa, Caroline Addison Carvalho Xavier de Medeiros, Gerlane Coelho Bernardo Guerra. Intestinal Anti-Inflammatory Activity of the Aqueous Extract from Ipomoea asarifolia in DNBS-Induced Colitis in Rats. International journal of molecular sciences. 2018 Dec; 19(12):. doi: 10.3390/ijms19124016. [PMID: 30545135]
  • Marika Cordaro, Daniela Impellizzeri, Enrico Gugliandolo, Rosalba Siracusa, Rosalia Crupi, Emanuela Esposito, Salvatore Cuzzocrea. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease. Molecular pharmacology. 2016 Nov; 90(5):549-561. doi: 10.1124/mol.116.105668. [PMID: 27625036]
  • Noureddine Bribi, Francesca Algieri, Alba Rodriguez-Nogales, Teresa Vezza, Jose Garrido-Mesa, María Pilar Utrilla, María Del Mar Contreras, Fadila Maiza, Antonio Segura-Carretero, Maria Elena Rodriguez-Cabezas, Julio Gálvez. Intestinal anti-inflammatory effects of total alkaloid extract from Fumaria capreolata in the DNBS model of mice colitis and intestinal epithelial CMT93 cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2016 Aug; 23(9):901-13. doi: 10.1016/j.phymed.2016.05.003. [PMID: 27387398]
  • Nidhi Goyal, Ajay Rana, Krishna Reddy V Bijjem, Puneet Kumar. Effect of chenodeoxycholic acid and sodium hydrogen sulfide in dinitro benzene sulfonic acid (DNBS)--Induced ulcerative colitis in rats. Pharmacological reports : PR. 2015 Jun; 67(3):616-23. doi: 10.1016/j.pharep.2014.12.018. [PMID: 25933978]
  • Vijay Morampudi, Ganive Bhinder, Xiujuan Wu, Chuanbin Dai, Ho Pan Sham, Bruce A Vallance, Kevan Jacobson. DNBS/TNBS colitis models: providing insights into inflammatory bowel disease and effects of dietary fat. Journal of visualized experiments : JoVE. 2014 Feb; ?(84):e51297. doi: 10.3791/51297. [PMID: 24637969]
  • Isabelle Olivier, Vassilia Theodorou, Philippe Valet, Isabelle Castan-Laurell, Laurent Ferrier, Hélène Eutamène. Modifications of mesenteric adipose tissue during moderate experimental colitis in mice. Life sciences. 2014 Jan; 94(1):1-7. doi: 10.1016/j.lfs.2013.09.028. [PMID: 24215755]
  • Helena Shifrin, Mirela Nadler-Milbauer, Shai Shoham, Marta Weinstock. Rivastigmine alleviates experimentally induced colitis in mice and rats by acting at central and peripheral sites to modulate immune responses. PloS one. 2013; 8(2):e57668. doi: 10.1371/journal.pone.0057668. [PMID: 23469045]
  • D Strøbæk, D T Brown, D P Jenkins, Y-J Chen, N Coleman, Y Ando, P Chiu, S Jørgensen, J Demnitz, H Wulff, P Christophersen. NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease. British journal of pharmacology. 2013 Jan; 168(2):432-44. doi: 10.1111/j.1476-5381.2012.02143.x. [PMID: 22891655]
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