DL-Tryptophan (BioDeep_00001868002)

Main id: BioDeep_00000000127

 

PANOMIX_OTCML-2023


代谢物信息卡片


DL-Tryptophan

化学式: C11H12N2O2 (204.0899)
中文名称: DL-色氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
InChI: InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)

描述信息

DL-Tryptophan is an endogenous metabolite.

同义名列表

3 个代谢物同义名

DL-Tryptophan; (±)-Tryptophan; Tryptophan



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALB, CA1, CAT, HDAC9, HMGB1, LPO, PPY, WARS1
Peripheral membrane protein 1 HMGB1
Endosome membrane 1 SLC6A4
Nucleus 6 ALB, HDAC9, HMGB1, SAP30, SAP30BP, WARS1
cytosol 6 ALB, CA1, CAT, TAT, TDO2, WARS1
centrosome 1 ALB
nucleoplasm 4 HDAC9, HMGB1, SAP30, SAP30BP
Cell membrane 2 HMGB1, SLC6A4
Multi-pass membrane protein 2 SLC38A9, SLC6A4
Synapse 1 SLC6A4
cell surface 1 HMGB1
Golgi apparatus 1 ALB
Golgi membrane 1 INS
lysosomal membrane 1 SLC38A9
mitochondrial inner membrane 1 ATP5ME
presynaptic membrane 1 SLC6A4
Lysosome 1 SLC38A9
Presynapse 1 SLC6A4
endosome 1 HMGB1
plasma membrane 3 GCG, HMGB1, SLC6A4
Membrane 2 CAT, SLC6A4
basolateral plasma membrane 1 LPO
extracellular exosome 6 ALB, CA1, CAT, CPVL, LPO, WARS1
Lysosome membrane 1 SLC38A9
endoplasmic reticulum 2 ALB, HMGB1
extracellular space 7 ALB, GCG, HMGB1, INS, LPO, PNLIP, PPY
mitochondrion 2 ATP5ME, CAT
protein-containing complex 3 ALB, CAT, WARS1
intracellular membrane-bounded organelle 1 CAT
Secreted 7 ALB, GCG, HMGB1, INS, LPO, PNLIP, PPY
extracellular region 8 ALB, CAT, GCG, HMGB1, INS, LPO, PNLIP, PPY
mitochondrial matrix 1 CAT
Extracellular side 1 HMGB1
anchoring junction 1 ALB
transcription regulator complex 1 HDAC9
postsynaptic membrane 1 SLC6A4
Membrane raft 1 SLC6A4
Cell junction, focal adhesion 1 SLC6A4
focal adhesion 2 CAT, SLC6A4
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Late endosome 1 SLC38A9
Cell projection, neuron projection 1 SLC6A4
neuron projection 1 SLC6A4
ciliary basal body 1 ALB
Late endosome membrane 1 SLC38A9
Chromosome 1 HMGB1
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Endomembrane system 1 SLC6A4
endosome lumen 1 INS
intermediate filament cytoskeleton 1 SAP30BP
ficolin-1-rich granule lumen 2 CAT, HMGB1
secretory granule lumen 4 CAT, GCG, HMGB1, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, GCG, INS
histone methyltransferase complex 1 HDAC9
transcription repressor complex 1 HMGB1
platelet alpha granule lumen 1 ALB
histone deacetylase complex 2 HDAC9, SAP30
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
Sin3-type complex 1 SAP30
FNIP-folliculin RagC/D GAP 1 SLC38A9
condensed chromosome 1 HMGB1
proton-transporting ATP synthase complex 1 ATP5ME
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
[Glucagon-like peptide 1]: Secreted 1 GCG
catalase complex 1 CAT
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
serotonergic synapse 1 SLC6A4
ciliary transition fiber 1 ALB


文献列表

  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • M Soledade C Pedras, Estifanos E Yaya, Erich Glawischnig. The phytoalexins from cultivated and wild crucifers: chemistry and biology. Natural product reports. 2011 Aug; 28(8):1381-405. doi: 10.1039/c1np00020a. [PMID: 21681321]
  • Rangan Mallik, David S Hage. Development of an affinity silica monolith containing human serum albumin for chiral separations. Journal of pharmaceutical and biomedical analysis. 2008 Apr; 46(5):820-30. doi: 10.1016/j.jpba.2007.03.017. [PMID: 17475436]
  • Ignacio Vayá, M Consuelo Jiménez, Miguel A Miranda. Excited-state interactions in flurbiprofen-tryptophan dyads. The journal of physical chemistry. B. 2007 Aug; 111(31):9363-71. doi: 10.1021/jp071301z. [PMID: 17608516]
  • Rangan Mallik, Tao Jiang, David S Hage. High-performance affinity monolith chromatography: development and evaluation of human serum albumin columns. Analytical chemistry. 2004 Dec; 76(23):7013-22. doi: 10.1021/ac049001q. [PMID: 15571354]
  • H Soderstrom, K Blennow, A Forsman, J Liesivuori, S Pennanen, J Tiihonen. A controlled study of tryptophan and cortisol in violent offenders. Journal of neural transmission (Vienna, Austria : 1996). 2004 Dec; 111(12):1605-10. doi: 10.1007/s00702-004-0219-7. [PMID: 15565494]
  • Hee Seung Kim, Young Sik Kye, David S Hage. Development and evaluation of N-hydroxysuccinimide-activated silica for immobilizing human serum albumin in liquid chromatography columns. Journal of chromatography. A. 2004 Sep; 1049(1-2):51-61. doi: 10.1016/s0021-9673(04)01338-x. [PMID: 15499917]
  • Xinbing Zuo, Kemin Wang, Leiji Zhou, Shasheng Huang. Separation and determination synchronously by multichannel mode-filtered light capillary electrochromatography. Electrophoresis. 2003 Sep; 24(18):3202-6. doi: 10.1002/elps.200305596. [PMID: 14518045]
  • N A Basova, Iu G Markov, N I Berzinia. [Effect of various methods of oxygenation in the isolated small intestine on the tryptophan and glycine accumulation]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2003 Aug; 89(8):1010-20. doi: . [PMID: 15119197]
  • M C Millot, N L Taleb, B Sebille. Binding of human serum albumin to silica particles by means of polymers: a liquid chromatographic study of the selectivity of resulting chiral stationary phases. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Feb; 768(1):157-66. doi: 10.1016/s0378-4347(01)00495-9. [PMID: 11939549]
  • W Schliemann, Y Cai, T Degenkolb, J Schmidt, H Corke. Betalains of Celosia argentea. Phytochemistry. 2001 Sep; 58(1):159-65. doi: 10.1016/s0031-9422(01)00141-8. [PMID: 11524126]
  • M C Millot, S Servagent-Noinville, N L Taleb, M H Baron, M Revault, B Sébille. Structural changes of human serum albumin immobilized on chromatographic supports: a high-performance liquid chromatography and Fourier-transform infrared spectroscopy study. Journal of chromatography. B, Biomedical sciences and applications. 2001 Mar; 753(1):101-13. doi: 10.1016/s0378-4347(00)00424-2. [PMID: 11302435]
  • T G Kulagina, T A Bykova, B V Lebedev. [Thermodynamic functions of lysozyme, myoglobin, beta-lactoglobulin, albumin, and poly-L-tryptophane in the temperature range 0-330 K]. Biofizika. 2001 Mar; 46(2):210-5. doi: NULL. [PMID: 11357331]
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