carmustine (BioDeep_00001867992)
Main id: BioDeep_00000006363
代谢物信息卡片
carmustine
化学式: C5H9Cl2N3O2 (213.0072)
中文名称: 卡莫司汀
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CCl)NC(=O)N(CCCl)N=O
InChI: InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
描述信息
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AD - Nitrosoureas
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D009676 - Noxae > D000477 - Alkylating Agents
D000970 - Antineoplastic Agents
同义名列表
3 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:3423
- KEGG: C06873
- KEGGdrug: D00254
- PubChem: 2578
- DrugBank: DB00262
- ChEMBL: CHEMBL513
- MeSH: Carmustine
- CAS: 154-93-8
- PubChem: 9090
- RefMet: Carmustine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Maha A Fahmy, Ayman A Farghaly, Entesar E Hassan, Zeinab M Hassan, Howaida I Abd-Alla. Protective role of Codiaeum variegatum against genotoxicity induced by carmustine in somatic and germ cells of male mice.
Molecular biology reports.
2022 Oct; 49(10):9543-9553. doi:
10.1007/s11033-022-07845-9. [PMID: 36053281] - Muhammed Enes Inanc, Sukru Gungor, Deniz Yeni, Fatih Avdatek, Volkan Ipek, Ruhi Turkmen, Orhan Corum, Harun Karaca, Ayhan Ata. Protective role of the dried white mulberry extract on the reproductive damage and fertility in rats treated with carmustine.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 May; 163(?):112979. doi:
10.1016/j.fct.2022.112979. [PMID: 35398183] - Christoph Sippl, Alexander Quiring, Fritz Teping, Walter Schulz-Schaeffer, Steffi Urbschat, Ralf Ketter, Joachim Oertel. MiRNA-181d Expression Correlates in Tumor versus Plasma of Glioblastoma Patients-the Base of a Preoperative Stratification Tool for Local Carmustine Wafer Use.
World neurosurgery.
2022 Mar; 159(?):e324-e333. doi:
10.1016/j.wneu.2021.12.053. [PMID: 34942386] - Matteo de Rosa, Simona Nonnis, Alessandro Aliverti. Covalent inhibition of P. falciparum ferredoxin-NADP+ reductase: Exploring alternative strategies for the development of new antimalarial drugs.
Biochemical and biophysical research communications.
2021 11; 577(?):89-94. doi:
10.1016/j.bbrc.2021.09.008. [PMID: 34509083] - Marie Nalin, Guillaume Hug, Eric Boeckmans, Christelle Machon, Bertrand Favier, Jérôme Guitton. Permeation measurement of 27 chemotherapy drugs after simulated dynamic testing on 15 surgical and examination gloves: A knowledge update.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Sep; 27(6):1395-1408. doi:
10.1177/1078155220950423. [PMID: 32847481] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Hongyan Ma, Huiyun Liang, Shengxin Cai, Barry R O'Keefe, Susan L Mooberry, Robert H Cichewicz. An Integrated Strategy for the Detection, Dereplication, and Identification of DNA-Binding Biomolecules from Complex Natural Product Mixtures.
Journal of natural products.
2021 03; 84(3):750-761. doi:
10.1021/acs.jnatprod.0c00946. [PMID: 33226219] - Chansik Hong, Seo Hwa Choi, Misun Kwak, Byeongseok Jeong, Juyeon Ko, Hyung Joon Park, Seok Choi, Jae Yeoul Jun, Insuk So. TRPC5 channel instability induced by depalmitoylation protects striatal neurons against oxidative stress in Huntington's disease.
Biochimica et biophysica acta. Molecular cell research.
2020 02; 1867(2):118620. doi:
10.1016/j.bbamcr.2019.118620. [PMID: 31812495] - Shufeng Yi, Fan Yang, Cunle Jie, Guiqin Zhang. A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care.
Artificial cells, nanomedicine, and biotechnology.
2019 Dec; 47(1):3438-3447. doi:
10.1080/21691401.2019.1652628. [PMID: 31411066] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Olena Rudyk, Philip Eaton. Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity.
Free radical biology & medicine.
2017 09; 110(?):390-398. doi:
10.1016/j.freeradbiomed.2017.07.007. [PMID: 28690194] - Vivek Bhat, Hemant Vira, Navin Khattry, Manoj Toshniwal. Cryptococcus laurentii diarrhea post hematopoietic stem cell transplant.
Transplant infectious disease : an official journal of the Transplantation Society.
2017 Apr; 19(2):. doi:
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Cardiovascular drugs and therapy.
2016 Oct; 30(5):433-443. doi:
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Klinicheskaia laboratornaia diagnostika.
2016 Aug; 61(8):474-8. doi:
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International journal of pharmaceutics.
2016 Feb; 499(1-2):10-19. doi:
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International journal of nanomedicine.
2016 ; 11(?):4065-75. doi:
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Transplantation.
2015 Dec; 99(12):2476-84. doi:
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Cancer chemotherapy and pharmacology.
2015 Nov; 76(5):939-48. doi:
10.1007/s00280-015-2866-9. [PMID: 26391155] - Paolo F Caimi, Basem M William, Carlos H Silva Rondon, Pingfu Fu, Brenda W Cooper, Erica L Campagnaro, Stanton L Gerson, Jane Reese-Koc, Robert Fox, Richard J Creger, Marcos de Lima, Hillard M Lazarus. Comparison of 2 Carmustine-Containing Regimens in the Rituximab Era: Excellent Outcomes Even in Poor-Risk Patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2015 Nov; 21(11):1926-31. doi:
10.1016/j.bbmt.2015.06.007. [PMID: 26087475] - S R R Lucas, R C Maranhão, J L Guerra, B M P Coelho, R Barboza, D H B Pozzi. Pilot clinical study of carmustine associated with a lipid nanoemulsion in combination with vincristine and prednisone for the treatment of canine lymphoma.
Veterinary and comparative oncology.
2015 Sep; 13(3):184-93. doi:
10.1111/vco.12033. [PMID: 23615221] - Patricia A Ford, Shakira J Grant, Rosemarie Mick, Gina Keck. Autologous Stem-Cell Transplantation Without Hematopoietic Support for the Treatment of Hematologic Malignancies in Jehovah's Witnesses.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2015 May; 33(15):1674-9. doi:
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Bone marrow transplantation.
2014 Sep; 49(9):1193-7. doi:
10.1038/bmt.2014.140. [PMID: 25000456] - Zengying Wu, Jose L Soulages, Bharat D Joshi, Stuart M Daniel, Zachary J Hager, Estela L Arrese. TGL-mediated lipolysis in Manduca sexta fat body: possible roles for lipoamide-dehydrogenase (LipDH) and high-density lipophorin (HDLp).
Insect biochemistry and molecular biology.
2014 Feb; 45(?):58-68. doi:
10.1016/j.ibmb.2013.12.001. [PMID: 24333838] - Frida Gustafsson, Alison J Foster, Sunil Sarda, Matthew H Bridgland-Taylor, J Gerry Kenna. A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Toxicological sciences : an official journal of the Society of Toxicology.
2014 Jan; 137(1):189-211. doi:
10.1093/toxsci/kft223. [PMID: 24085192] - Lili Qian, Jiajun Zheng, Ke Wang, Ying Tang, Xiaofeng Zhang, Haishi Zhang, Fengping Huang, Yuanying Pei, Yanyan Jiang. Cationic core-shell nanoparticles with carmustine contained within O⁶-benzylguanine shell for glioma therapy.
Biomaterials.
2013 Nov; 34(35):8968-78. doi:
10.1016/j.biomaterials.2013.07.097. [PMID: 23953782] - Yung-Chih Kuo, Chun-Yuan Shih-Huang. Solid lipid nanoparticles carrying chemotherapeutic drug across the blood-brain barrier through insulin receptor-mediated pathway.
Journal of drug targeting.
2013 Sep; 21(8):730-8. doi:
10.3109/1061186x.2013.812094. [PMID: 23815407] - James L Slack, Amylou C Dueck, Veena D Fauble, Lisa O Sproat, Craig B Reeder, Pierre Noel, Nandita Khera, Jeffery A Betcher, Jared L Klein, Jose F Leis, Roberta H Adams. Reduced toxicity conditioning and allogeneic stem cell transplantation in adults using fludarabine, carmustine, melphalan, and antithymocyte globulin: outcomes depend on disease risk index but not age, comorbidity score, donor type, or human leukocyte antigen mismatch.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2013 Aug; 19(8):1167-74. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2012 Dec; 40(12):2332-41. doi:
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The American journal of pathology.
2012 Nov; 181(5):1870-8. doi:
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International journal of biological macromolecules.
2012 Jun; 50(5):1322-6. doi:
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Journal of cellular biochemistry.
2012 May; 113(5):1645-53. doi:
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Journal of experimental & clinical cancer research : CR.
2012 Feb; 31(?):13. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2012 Jan; 40(1):130-8. doi:
10.1124/dmd.111.040758. [PMID: 21965623] - Jane Li, Amit Khot, Kate Burbury. Acute kidney injury requiring dialysis following carmustine and etoposide during autologous stem cell transplantation.
Chemotherapy.
2012; 58(5):349-51. doi:
10.1159/000343661. [PMID: 23171711] - Alice A Ramos, Dalila Pedro, Andrew R Collins, Cristina Pereira-Wilson. Protection by Salvia extracts against oxidative and alkylation damage to DNA in human HCT15 and CO115 cells.
Journal of toxicology and environmental health. Part A.
2012; 75(13-15):765-75. doi:
10.1080/15287394.2012.689804. [PMID: 22788364] - Svjetlana Raus, Silvia Coin, Vladia Monsurrò. Adenovirus as a new agent for multiple myeloma therapies: Opportunities and restrictions.
The Korean journal of hematology.
2011 Dec; 46(4):229-38. doi:
10.5045/kjh.2011.46.4.229. [PMID: 22259628] - R Stupp, A Tosoni, J E C Bromberg, P Hau, M Campone, J Gijtenbeek, M Frenay, L Breimer, H Wiesinger, A Allgeier, M J van den Bent, U Bogdahn, W van der Graaf, H J Yun, T Gorlia, D Lacombe, A A Brandes. Sagopilone (ZK-EPO, ZK 219477) for recurrent glioblastoma. A phase II multicenter trial by the European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group.
Annals of oncology : official journal of the European Society for Medical Oncology.
2011 Sep; 22(9):2144-2149. doi:
10.1093/annonc/mdq729. [PMID: 21321091] - Osama S El-Tawil, Ali H Abou-Hadeed, Mohamed F El-Bab, Abeir A Shalaby. d-Amphetamine-induced cytotoxicity and oxidative stress in isolated rat hepatocytes.
Pathophysiology : the official journal of the International Society for Pathophysiology.
2011 Sep; 18(4):279-85. doi:
10.1016/j.pathophys.2011.04.001. [PMID: 21571509] - El-Sayed M El-Sayed, Abdel-Aziz H Abdel-Aziz, Samira Saleh, Ahmed S Saad. The chemopreventive effect of dimethylthiourea against carmustine-induced myelotoxicity in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Sep; 49(9):1965-9. doi:
10.1016/j.fct.2011.05.007. [PMID: 21620922] - Eric M Bessell, Peter Dickinson, Stephen Dickinson, Jennifer Salmon. Increasing age at diagnosis and worsening renal function in patients with primary central nervous system lymphoma.
Journal of neuro-oncology.
2011 Aug; 104(1):191-3. doi:
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Lung India : official organ of Indian Chest Society.
2011 Apr; 28(2):136-8. doi:
10.4103/0970-2113.80331. [PMID: 21712927] - Yung-Chih Kuo, Cheng-Te Liang. Inhibition of human brain malignant glioblastoma cells using carmustine-loaded catanionic solid lipid nanoparticles with surface anti-epithelial growth factor receptor.
Biomaterials.
2011 Apr; 32(12):3340-50. doi:
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PloS one.
2011 Mar; 6(3):e18012. doi:
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International journal of nanomedicine.
2011; 6(?):2285-95. doi:
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Case reports in dentistry.
2011; 2011(?):568246. doi:
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Chemotherapy research and practice.
2011; 2011(?):175054. doi:
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British journal of cancer.
2010 Dec; 103(12):1815-21. doi:
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Archives of virology.
2010 Dec; 155(12):2007-15. doi:
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Investigational new drugs.
2010 Dec; 28 Suppl 1(?):S28-35. doi:
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Toxins.
2010 11; 2(11):2519-83. doi:
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Toxins.
2010 11; 2(11):2645-62. doi:
10.3390/toxins2112645. [PMID: 22069569] - Chiara Gallo, Carlo Buonerba, Giuseppe Di Lorenzo, Valeria Romeo, Sabino De Placido, Alfredo Marinelli. Can high-dose fotemustine reverse MGMT resistance in glioblastoma multiforme?.
Journal of neuro-oncology.
2010 Nov; 100(2):311-9. doi:
10.1007/s11060-010-0168-y. [PMID: 20556481] - Cristina P Almeida, Carolina G Vital, Thais C Contente, Durvanei A Maria, Raul C Maranhão. Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake.
International journal of nanomedicine.
2010 Sep; 5(?):679-86. doi:
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2010 Jun; 48(6):1576-80. doi:
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Journal of agricultural and food chemistry.
2010 Feb; 58(3):1630-8. doi:
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Journal of nucleic acids.
2010; 2010(?):. doi:
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The oncologist.
2010; 15(1):6-25. doi:
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Drug and chemical toxicology.
2010; 33(1):55-63. doi:
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Archiv der Pharmazie.
2009 Nov; 342(11):632-9. doi:
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Toxicology in vitro : an international journal published in association with BIBRA.
2009 Sep; 23(6):992-9. doi:
10.1016/j.tiv.2009.06.023. [PMID: 19560534] - Lee Roy Morgan, Robert F Struck, William R Waud, Blaise LeBlanc, Andrew H Rodgers, Branko S Jursic. Carbonate and carbamate derivatives of 4-demethylpenclomedine as novel anticancer agents.
Cancer chemotherapy and pharmacology.
2009 Sep; 64(4):829-35. doi:
10.1007/s00280-009-0933-9. [PMID: 19255760] - Thissiane L Gonçalves, Dalila M Benvegnú, Gabriela Bonfanti, Andressa V Frediani, João Batista T Rocha. Delta-ALA-D activity is a reliable marker for oxidative stress in bone marrow transplant patients.
BMC cancer.
2009 May; 9(?):138. doi:
10.1186/1471-2407-9-138. [PMID: 19426494] - S Schippling, R Martin. [Stem cell therapy in multiple sclerosis: a clinical update].
Zeitschrift fur Rheumatologie.
2009 May; 68(3):214-5, 217. doi:
10.1007/s00393-008-0392-4. [PMID: 19399509] - Thissiane L Gonçalves, Dalila M Benvegnú, Gabriela Bonfanti, Andressa V Frediani, João B T Rocha. delta-Aminolevulinate dehydratase activity and oxidative stress during melphalan and cyclophosphamide-BCNU-etoposide (CBV) conditioning regimens in autologous bone marrow transplantation patients.
Pharmacological research.
2009 Apr; 59(4):279-84. doi:
10.1016/j.phrs.2008.12.005. [PMID: 19162187] - ChunSheng Kang, XuBo Yuan, Yue Zhong, PeiYu Pu, YanShuang Guo, Ammar Albadany, ShiZhu Yu, ZhiYong Zhang, YanHe Li, Jin Chang, Jing Sheng. Growth inhibition against intracranial C6 glioma cells by stereotactic delivery of BCNU by controlled release from poly(D,L-lactic acid) nanoparticles.
Technology in cancer research & treatment.
2009 Feb; 8(1):61-70. doi:
10.1177/153303460900800108. [PMID: 19166243] - Gouda Kamel Helal, Omayma K Helal. Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary fibrosis in rats.
Archives of toxicology.
2009 Jan; 83(1):87-94. doi:
10.1007/s00204-008-0325-7. [PMID: 18528683] - Barbara Ingold, Peter Schraml, Frank L Heppner, Holger Moch. Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.
PloS one.
2009; 4(3):e4775. doi:
10.1371/journal.pone.0004775. [PMID: 19274096] - R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1385-405. doi:
10.1124/dmd.108.020479. [PMID: 18426954] - Vincent Launay-Vacher, Corinne Isnard-Bagnis, Nicolas Janus, Svetlana Karie, Gilbert Deray. [Chemotherapy and renal toxicity].
Bulletin du cancer.
2008 May; 95 FMC Onco(?):F96-103. doi:
10.1684/bdc.2007.0544. [PMID: 18511375] - Angela Dispenzieri, Martha Q Lacy, Suzanne R Hayman, Shaji K Kumar, Francis Buadi, David Dingli, Mark R Litzow, Dennis A Gastineau, David J Inwards, Michelle A Elliott, Ivana N Micallef, Stephen M Ansell, William J Hogan, Luis F Porrata, Patrick A Johnston, Bekele Afessa, Alan Bryce, Robert A Kyle, Morie A Gertz. Peripheral blood stem cell transplant for POEMS syndrome is associated with high rates of engraftment syndrome.
European journal of haematology.
2008 May; 80(5):397-406. doi:
10.1111/j.1600-0609.2008.01037.x. [PMID: 18221391] - Shailendra Joshi, Mei Wang, Joshua J Etu, Raymond F Suckow, Thomas B Cooper, Steven J Feinmark, Jeffrey N Bruce, Robert L Fine. Transient cerebral hypoperfusion enhances intraarterial carmustine deposition into brain tissue.
Journal of neuro-oncology.
2008 Jan; 86(2):123-32. doi:
10.1007/s11060-007-9450-z. [PMID: 17634743] - Kazunori Fujimoto, Shingo Arakawa, Toshiyuki Watanabe, Hiroaki Yasumo, Yosuke Ando, Wataru Takasaki, Sunao Manabe, Takashi Yamoto, Sen-Ichi Oda. Generation and functional characterization of mice with a disrupted glutathione S-transferase, theta 1 gene.
Drug metabolism and disposition: the biological fate of chemicals.
2007 Dec; 35(12):2196-202. doi:
10.1124/dmd.107.017905. [PMID: 17827337] - A R Murray, E Kisin, V Castranova, C Kommineni, M R Gunther, A A Shvedova. Phenol-induced in vivo oxidative stress in skin: evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion.
Chemical research in toxicology.
2007 Dec; 20(12):1769-77. doi:
10.1021/tx700201z. [PMID: 17922553] - Eric D Batts, Christopher Maisel, Donna Kane, Lili Liu, Pingfu Fu, Timothy O'Brien, Scot Remick, Nizar Bahlis, Stanton L Gerson. O6-benzylguanine and BCNU in multiple myeloma: a phase II trial.
Cancer chemotherapy and pharmacology.
2007 Aug; 60(3):415-21. doi:
10.1007/s00280-007-0442-7. [PMID: 17354015] - A Lalaouni, C Henderson, C Kupper, M H Grant. The interaction of chromium (VI) with macrophages: depletion of glutathione and inhibition of glutathione reductase.
Toxicology.
2007 Jul; 236(1-2):76-81. doi:
10.1016/j.tox.2007.04.002. [PMID: 17498860] - Matthew G Ewend, Steven Brem, Mark Gilbert, Robert Goodkin, Paul L Penar, Mahesh Varia, Sharon Cush, Lisa A Carey. Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2007 Jun; 13(12):3637-41. doi:
10.1158/1078-0432.ccr-06-2095. [PMID: 17575228] - Po Yee Chiu, Hoi Yan Leung, Ada H Y Siu, Michel K T Poon, Tina T X Dong, Karl W K Tsim, Kam Ming Ko. Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: role of glutathione synthesis and regeneration.
Planta medica.
2007 Feb; 73(2):134-41. doi:
10.1055/s-2006-957068. [PMID: 17325989] - Susan Murphy, Frances M Boyle, Ross A Davey, Xiao-Qing Gu, Laurence E Mather. Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU.
The Journal of pharmacy and pharmacology.
2007 Jan; 59(1):105-14. doi:
10.1211/jpp.59.1.0014. [PMID: 17227627] - Henrikas Nivinskas, Ausra Nemeikaite-Ceniene, Audrone Maroziene, Terese Normantiene, Narimantas Cenas. Prooxidant cytotoxicity of chromate in mammalian cells: the opposite roles of DT-diaphorase and glutathione reductase.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2006 Nov; 61(11-12):889-95. doi:
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British journal of cancer.
2006 Oct; 95(7):829-34. doi:
10.1038/sj.bjc.6603331. [PMID: 16969355] - Adrienne C Scheck, Krya Perry, Nicole C Hank, W Dennis Clark. Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells.
BMC complementary and alternative medicine.
2006 Aug; 6(?):27. doi:
10.1186/1472-6882-6-27. [PMID: 16914050] - T Kuittinen, E Jantunen, E Vanninen, H Mussalo, O Vuolteenaho, M Ala-Kopsala, T Nousiainen, J Hartikainen. Cardiac effects within 3 months of BEAC high-dose therapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation.
European journal of haematology.
2006 Aug; 77(2):120-7. doi:
10.1111/j.1600-0609.2006.00687.x. [PMID: 16856907] - M E de Jonge, A D R Huitema, J H Beijnen, S Rodenhuis. High exposures to bioactivated cyclophosphamide are related to the occurrence of veno-occlusive disease of the liver following high-dose chemotherapy.
British journal of cancer.
2006 May; 94(9):1226-30. doi:
10.1038/sj.bjc.6603097. [PMID: 16622453] - Robert A Kyle, Traci Leong, Shuli Li, Martin M Oken, Neil E Kay, Brian Van Ness, Philip R Greipp. Complete response in multiple myeloma: clinical trial E9486, an Eastern Cooperative Oncology Group study not involving stem cell transplantation.
Cancer.
2006 May; 106(9):1958-66. doi:
10.1002/cncr.21804. [PMID: 16565956] - M Bayes, X Rabasseda, J R Prous. Gateways to clinical trials.
Methods and findings in experimental and clinical pharmacology.
2006 Mar; 28(2):121-42. doi:
. [PMID: 16636723] - Oscar A Bizzozero, Jennifer L Ziegler, Gisela De Jesus, Federico Bolognani. Acute depletion of reduced glutathione causes extensive carbonylation of rat brain proteins.
Journal of neuroscience research.
2006 Mar; 83(4):656-67. doi:
10.1002/jnr.20771. [PMID: 16447283] - I-Chang Su, Huang-Chun Lien, Chang-Mu Chen. Primary brain T-cell lymphoma after kidney transplantation: a case report.
Surgical neurology.
2006; 66 Suppl 2(?):S60-3. doi:
10.1016/j.surneu.2006.05.024. [PMID: 17071259] - Ryan J Hansen, Ramamoorthy Nagasubramanian, Shannon M Delaney, Mathew M Cherian, Shang Lin, Scott C Kogan, M Eileen Dolan. Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
The Journal of pharmacology and experimental therapeutics.
2005 Dec; 315(3):1247-55. doi:
10.1124/jpet.105.083501. [PMID: 16126841] - T Kuittinen, M Husso-Saastamoinen, P Sipola, O Vuolteenaho, M Ala-Kopsala, T Nousiainen, E Jantunen, J Hartikainen. Very acute cardiac toxicity during BEAC chemotherapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation.
Bone marrow transplantation.
2005 Dec; 36(12):1077-82. doi:
10.1038/sj.bmt.1705175. [PMID: 16247436] - Ausra Nemeikaite-Ceniene, Audrone Maroziene, Audrius Pukalskas, Petras Rimantas Venskutonis, Narimantas Cenas. Redox properties of novel antioxidant 5,8-Dihydroxycoumarin: implications for its prooxidant cytotoxicity.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2005 Nov; 60(11-12):849-54. doi:
10.1515/znc-2005-11-1206. [PMID: 16402544] - Ausra Nemeikaite-Ceniene, Ausra Imbrasaite, Egle Sergediene, Narimantas Cenas. Quantitative structure-activity relationships in prooxidant cytotoxicity of polyphenols: role of potential of phenoxyl radical/phenol redox couple.
Archives of biochemistry and biophysics.
2005 Sep; 441(2):182-90. doi:
10.1016/j.abb.2005.07.002. [PMID: 16111645] - William P Petros, Penelope J Hopkins, Susan Spruill, Gloria Broadwater, James J Vredenburgh, O Michael Colvin, William P Peters, Roy B Jones, Jeff Hall, Jeffrey R Marks. Associations between drug metabolism genotype, chemotherapy pharmacokinetics, and overall survival in patients with breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2005 Sep; 23(25):6117-25. doi:
10.1200/jco.2005.06.075. [PMID: 16087946] - Andrew R Humpage, Frank Fontaine, Suzanne Froscio, Philip Burcham, Ian R Falconer. Cylindrospermopsin genotoxicity and cytotoxicity: role of cytochrome P-450 and oxidative stress.
Journal of toxicology and environmental health. Part A.
2005 May; 68(9):739-53. doi:
10.1080/15287390590925465. [PMID: 16020200] - J I Cohen. HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma.
British journal of cancer.
2005 May; 92(9):1593-8. doi:
10.1038/sj.bjc.6602561. [PMID: 15856040] - Michael S Bobola, John R Silber, Richard G Ellenbogen, J Russell Geyer, A Blank, Ryan D Goff. O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005 Apr; 11(7):2747-55. doi:
10.1158/1078-0432.ccr-04-2045. [PMID: 15814657] - Panduranga S Rao. Nephrotic syndrome in patients with peripheral blood stem cell transplant.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2005 Apr; 45(4):780-5. doi:
10.1053/j.ajkd.2005.01.003. [PMID: 15806483] - Kihang Choi, Matthew Siegel, Justin L Piper, Liya Yuan, Eun Cho, Pavel Strnad, Bishr Omary, Keith M Rich, Chaitan Khosla. Chemistry and biology of dihydroisoxazole derivatives: selective inhibitors of human transglutaminase 2.
Chemistry & biology.
2005 Apr; 12(4):469-75. doi:
10.1016/j.chembiol.2005.02.007. [PMID: 15850984] - Riccardo Saccardi, Gian Luigi Mancardi, Alessandra Solari, Alberto Bosi, Paolo Bruzzi, Paolo Di Bartolomeo, Amedea Donelli, Massimo Filippi, Angelo Guerrasio, Francesca Gualandi, Giorgio La Nasa, Alessandra Murialdo, Francesca Pagliai, Federico Papineschi, Barbara Scappini, Alberto M Marmont. Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life.
Blood.
2005 Mar; 105(6):2601-7. doi:
10.1182/blood-2004-08-3205. [PMID: 15546956]
