ISOQUINOLINE (BioDeep_00001867984)
Main id: BioDeep_00000002906
代谢物信息卡片
化学式: C9H7N (129.0578462)
中文名称: 异喹啉
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C=NC=CC2=C1
InChI: InChI=1S/C9H7N/c1-2-4-9-7-10-6-5-8(9)3-1/h1-7H
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:16092
- KEGG: C06323
- PubChem: 8405
- DrugBank: DB04329
- ChEMBL: CHEMBL12315
- CAS: 2241982-85-2
- CAS: 119-65-3
- PubChem: 8559
- PDB-CCD: ISQ
- 3DMET: B00931
- NIKKAJI: J43.394B
- RefMet: Isoquinoline
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
5 个相关的物种来源信息
- 105884 Lonicera japonica: 10.3390/MOLECULES18021368
- 88149 Saccharina japonica: 10.3390/MOLECULES200712093
- 105884 Lonicera japonica: 10.3390/MOLECULES18021368
- 88149 Saccharina japonica: 10.3390/MOLECULES200712093
- 569774 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Erika Plazas, Mónica C Avila M, Diego R Muñoz, Luis E Cuca S. Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases.
Pharmacological research.
2022 03; 177(?):106126. doi:
10.1016/j.phrs.2022.106126
. [PMID: 35151857] - Emmanoel V Costa, Liviane do N Soares, Jamal da Silva Chaar, Valdenizia R Silva, Luciano de S Santos, Hector H F Koolen, Felipe M A da Silva, Josean F Tavares, Gokhan Zengin, Milena B P Soares, Daniel P Bezerra. Benzylated Dihydroflavones and Isoquinoline-Derived Alkaloids from the Bark of Diclinanona calycina (Annonaceae) and Their Cytotoxicities.
Molecules (Basel, Switzerland).
2021 Jun; 26(12):. doi:
10.3390/molecules26123714
. [PMID: 34207059] - Yang Huang, Tiejie Wang, Zhengjin Jiang. Fast analysis of alkaloids from different parts of Mahonia bealei (Fort.) Carr. studied for their anti-Alzheimer's activity using supercritical fluid chromatography.
Journal of separation science.
2021 May; 44(9):2006-2014. doi:
10.1002/jssc.202001079
. [PMID: 33650266] - Daniela Marasco, Caterina Vicidomini, Pawel Krupa, Federica Cioffi, Pham Dinh Quoc Huy, Mai Suan Li, Daniele Florio, Kerensa Broersen, Maria Francesca De Pandis, Giovanni N Roviello. Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation.
Chemico-biological interactions.
2021 Jan; 334(?):109300. doi:
10.1016/j.cbi.2020.109300
. [PMID: 33098838] - Huan Xia, Yitong Liu, Guiyang Xia, Yi Liu, Sheng Lin, Lijia Guo. Novel Isoquinoline Alkaloid Litcubanine A - A Potential Anti-Inflammatory Candidate.
Frontiers in immunology.
2021; 12(?):685556. doi:
10.3389/fimmu.2021.685556
. [PMID: 34163484] - Jun-Yan Xiang, Yan-Yu Chi, Jin-Xin Han, Hongyu Xiang, Qiuhong Xie. The Toxicity and Attenuation Methods of Toxic Chinese Materia Medica for its Reasonable Application: A Review.
The American journal of Chinese medicine.
2021; 49(1):41-67. doi:
10.1142/s0192415x21500038
. [PMID: 33416023] - Lin-Hai Chen, Qing Zhang, Xin Xie, Fa-Jun Nan. Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists.
Journal of medicinal chemistry.
2020 12; 63(24):15399-15409. doi:
10.1021/acs.jmedchem.0c01378
. [PMID: 33267584] - Zhihui Liu, Zhenru Mi, Panpan Wang, Sheng Chang, Na Han, Jun Yin. Two new alkaloids from the tubers of Corydalis ambigua subsp. amurensis and their anti-proliferative activity.
Natural product research.
2020 Dec; 34(23):3305-3312. doi:
10.1080/14786419.2019.1566821
. [PMID: 30908089] - Jing-Jing Xue, Chun-Yu Jiang, De-Li Zou, Bin-Jie Li, Jin-Cai Lu, Da-Hong Li, Bin Lin, Zhan-Lin Li, Hui-Ming Hua. Baicalensines A and B, Two Isoquinoline Alkaloids from the Roots of Thalictrum baicalense.
Organic letters.
2020 10; 22(19):7439-7442. doi:
10.1021/acs.orglett.0c02444
. [PMID: 32886519] - Ruifei Zhang, Qiang Guo, Edward J Kennelly, Chunlin Long, Xingyun Chai. Diverse alkaloids and biological activities of Fumaria (Papaveraceae): An ethnomedicinal group.
Fitoterapia.
2020 Oct; 146(?):104697. doi:
10.1016/j.fitote.2020.104697
. [PMID: 32739338] - Kaho Hirai, Saiichiro Watanabe, Nozomi Nishijima, Kaoru Shibata, Akane Hase, Tsuyoshi Yamanaka, Masato Inazu. Molecular and Functional Analysis of Choline Transporters and Antitumor Effects of Choline Transporter-Like Protein 1 Inhibitors in Human Pancreatic Cancer Cells.
International journal of molecular sciences.
2020 Jul; 21(15):. doi:
10.3390/ijms21155190
. [PMID: 32707889] - Kwangho Song, Jae-Hyeon Oh, Min Young Lee, Seok-Geun Lee, In Jin Ha. Molecular Network-Guided Alkaloid Profiling of Aerial Parts of Papaver nudicaule L. Using LC-HRMS.
Molecules (Basel, Switzerland).
2020 Jun; 25(11):. doi:
10.3390/molecules25112636
. [PMID: 32517053] - Erika Plazas, Stefanie Hagenow, Monica Avila Murillo, Holger Stark, Luis Enrique Cuca. Isoquinoline alkaloids from the roots of Zanthoxylum rigidum as multi-target inhibitors of cholinesterase, monoamine oxidase A and Aβ1-42 aggregation.
Bioorganic chemistry.
2020 05; 98(?):103722. doi:
10.1016/j.bioorg.2020.103722
. [PMID: 32155491] - Mohamed A Tantawy, Farid M Sroor, Magda F Mohamed, Mostafa E El-Naggar, Fatma M Saleh, Hamdi M Hassaneen, Ismail A Abdelhamid. Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer.
Anti-cancer agents in medicinal chemistry.
2020; 20(1):70-83. doi:
10.2174/1871520619666191024121116
. [PMID: 31696811] - Shih-Yi Lee, Ling-Wei Hsin, Ming-Jai Su, Ching-Chia ChangChien, Hui-Chun Ku. A novel isoquinoline derivative exhibits anti-inflammatory properties and improves the outcomes of endotoxemia.
Pharmacological reports : PR.
2019 Dec; 71(6):1281-1288. doi:
10.1016/j.pharep.2019.06.015
. [PMID: 31683199] - Jerald J Nair, Johannes van Staden. Antiprotozoal alkaloid principles of the plant family Amaryllidaceae.
Bioorganic & medicinal chemistry letters.
2019 10; 29(20):126642. doi:
10.1016/j.bmcl.2019.126642
. [PMID: 31515186] - Anna Petruczynik, Tomasz Tuzimski, Tomasz Plech, Justyna Misiurek, Karolina Szalast, Grażyna Szymczak. Comparison of Anticancer Activity and HPLC-DAD Determination of Selected Isoquinoline Alkaloids from Thalictrum foetidum, Berberis sp. and Chelidonium majus Extracts.
Molecules (Basel, Switzerland).
2019 Sep; 24(19):. doi:
10.3390/molecules24193417
. [PMID: 31547046] - Cai-Feng Ding, Zhi Dai, Hao-Fei Yu, Xu-Dong Zhao, Xiao-Dong Luo. New aporphine alkaloids with selective cytotoxicity against glioma stem cells from Thalictrum foetidum.
Chinese journal of natural medicines.
2019 Sep; 17(9):698-706. doi:
10.1016/s1875-5364(19)30084-6
. [PMID: 31526505] - Zhong-Min Zhao, Xiao-Fei Shang, Raymond Kobla Lawoe, Ying-Qian Liu, Rui Zhou, Yu Sun, Yin-Fang Yan, Jun-Cai Li, Guan-Zhou Yang, Cheng-Jie Yang. Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine.
Pesticide biochemistry and physiology.
2019 Sep; 159(?):51-58. doi:
10.1016/j.pestbp.2019.05.015
. [PMID: 31400784] - Yuan Tian, Wei Gui, Philip B Smith, Imhoi Koo, Iain A Murray, Margherita T Cantorna, Gary H Perdew, Andrew D Patterson. Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agaricus bisporus).
Journal of agricultural and food chemistry.
2019 Aug; 67(33):9286-9294. doi:
10.1021/acs.jafc.9b03212
. [PMID: 31339733] - Wei Li, Guotong Wang, Jixing Lai, Shengkun Li. Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance.
Chemical communications (Cambridge, England).
2019 May; 55(42):5902-5905. doi:
10.1039/c9cc01790a
. [PMID: 31045188] - Manju Bala, Shiv Kumar, Kunal Pratap, Praveen Kumar Verma, Yogendra Padwad, Bikram Singh. Bioactive isoquinoline alkaloids from Cissampelos pareira †.
Natural product research.
2019 Mar; 33(5):622-627. doi:
10.1080/14786419.2017.1402319
. [PMID: 29126362] - Chunshun Li, Ariel M Sarotti, Xiaohua Wu, Baojun Yang, James Turkson, Yongfei Chen, Qingsong Liu, Shugeng Cao. An Unusual Benzoisoquinoline-9-one Derivative and Other Related Compounds with Antiproliferative Activity from Hawaiian Endophytic Fungus Peyronellaea sp. FT431.
Molecules (Basel, Switzerland).
2019 Jan; 24(1):. doi:
10.3390/molecules24010196
. [PMID: 30621059] - Nick Barton, Máire Convery, Anthony W J Cooper, Kenneth Down, J Nicole Hamblin, Graham Inglis, Simon Peace, James Rowedder, Paul Rowland, Jonathan A Taylor, Natalie Wellaway. Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach.
Journal of medicinal chemistry.
2018 12; 61(24):11061-11073. doi:
10.1021/acs.jmedchem.8b01556
. [PMID: 30532965] - Shaimaa Fayez, Doris Feineis, Laurent Aké Assi, Marcel Kaiser, Reto Brun, Suresh Awale, Gerhard Bringmann. Ancistrobrevines E-J and related naphthylisoquinoline alkaloids from the West African liana Ancistrocladus abbreviatus with inhibitory activities against Plasmodium falciparum and PANC-1 human pancreatic cancer cells.
Fitoterapia.
2018 Nov; 131(?):245-259. doi:
10.1016/j.fitote.2018.11.006
. [PMID: 30419265] - Séverin Muyisa Kavatsurwa, Blaise Kimbadi Lombe, Doris Feineis, Dya Fita Dibwe, Vinesh Maharaj, Suresh Awale, Gerhard Bringmann. Ancistroyafungines A-D, 5,8'- and 5,1'-coupled naphthylisoquinoline alkaloids from a Congolese Ancistrocladus species, with antiausterity activities against human PANC-1 pancreatic cancer cells.
Fitoterapia.
2018 Oct; 130(?):6-16. doi:
10.1016/j.fitote.2018.07.017
. [PMID: 30059720] - Mao-Sheng Zhang, Yan Deng, Shao-Bin Fu, Da-Le Guo, Shi-Ji Xiao. Mahimbrine A, a Novel Isoquinoline Alkaloid Bearing a Benzotropolone Moiety from Mahonia imbricata.
Molecules (Basel, Switzerland).
2018 Jun; 23(7):. doi:
10.3390/molecules23071539
. [PMID: 29949909] - Kjell A Svensson, Beverly A Heinz, John M Schaus, James P Beck, Junliang Hao, Joseph H Krushinski, Matthew R Reinhard, Michael P Cohen, Sarah L Hellman, Brian G Getman, Xushan Wang, Michelle M Menezes, Deanna L Maren, Julie F Falcone, Wesley H Anderson, Rebecca A Wright, S Michelle Morin, Kelly L Knopp, Benjamin L Adams, Borys Rogovoy, Ilya Okun, Todd M Suter, Michael A Statnick, Donald R Gehlert, David L Nelson, Virginia L Lucaites, Renee Emkey, Neil W DeLapp, Todd R Wiernicki, Jeffrey W Cramer, Charles R Yang, Robert F Bruns. An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or Tachyphylaxis.
The Journal of pharmacology and experimental therapeutics.
2017 Jan; 360(1):117-128. doi:
10.1124/jpet.116.236372
. [PMID: 27811173] - Li-Hong Ye, Xi-De Liu, Jun Cao, Yan-Xu Chang, Mingrui An, Shu-Ling Wang, Jing-Jing Xu, Li-Qing Peng. Analysis of isoquinoline alkaloids using chitosan-assisted liquid-solid extraction followed by microemulsion liquid chromatography employing a sub-2-micron particle stationary phase.
Electrophoresis.
2016 12; 37(23-24):3118-3125. doi:
10.1002/elps.201600114
. [PMID: 27699822] - Le Quynh Lien, Tran My Linh, Vu Huong Giang, Nguyen Chi Mai, Nguyen Xuan Nhiem, Bui Huu Tai, Nguyen Thi Cuc, Hoang Le Tuan Anh, Ninh Khac Ban, Chau Van Minh, Phan Van Kiem. New naphthalene derivatives and isoquinoline alkaloids from Ancistrocladus cochinchinensis with their anti-proliferative activity on human cancer cells.
Bioorganic & medicinal chemistry letters.
2016 08; 26(16):3913-7. doi:
10.1016/j.bmcl.2016.07.014
. [PMID: 27423477] - Joshua A Baccile, Joseph E Spraker, Henry H Le, Eileen Brandenburger, Christian Gomez, Jin Woo Bok, Juliane Macheleidt, Axel A Brakhage, Dirk Hoffmeister, Nancy P Keller, Frank C Schroeder. Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus.
Nature chemical biology.
2016 06; 12(6):419-24. doi:
10.1038/nchembio.2061
. [PMID: 27065235] - Xianbao Deng, Lingping Zhu, Ting Fang, Sornkanok Vimolmangkang, Dong Yang, Collins Ogutu, Yanling Liu, Yuepeng Han. Analysis of Isoquinoline Alkaloid Composition and Wound-Induced Variation in Nelumbo Using HPLC-MS/MS.
Journal of agricultural and food chemistry.
2016 Feb; 64(5):1130-6. doi:
10.1021/acs.jafc.5b06099
. [PMID: 26800445] - Hengjia Ni, Yordan Martínez, Guiping Guan, Román Rodríguez, Dairon Más, Hanhui Peng, Manuel Valdivié Navarro, Gang Liu. Analysis of the Impact of Isoquinoline Alkaloids, Derived from Macleaya cordata Extract, on the Development and Innate Immune Response in Swine and Poultry.
BioMed research international.
2016; 2016(?):1352146. doi:
10.1155/2016/1352146
. [PMID: 28042566] - Kaisa A Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio, Maija Lahtela-Kakkonen. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis.
Drug metabolism and disposition: the biological fate of chemicals.
2015 Dec; 43(12):1891-904. doi:
10.1124/dmd.115.065755
. [PMID: 26400396] - Valery M Dembitsky, Tatyana A Gloriozova, Vladimir V Poroikov. Naturally occurring plant isoquinoline N-oxide alkaloids: their pharmacological and SAR activities.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2015 Jan; 22(1):183-202. doi:
10.1016/j.phymed.2014.11.002
. [PMID: 25636889] - Tsvetelina Doncheva, Amgalan Solongo, Nadezhda Kostova, Yadamsuren Gerelt-Od, Dangaa Selenge, Stefan Philipov. Leptopyrine, new alkaloid from Leptopyrum fumarioides L. (Ranunculaceae).
Natural product research.
2015; 29(9):853-6. doi:
10.1080/14786419.2014.991322
. [PMID: 25529023] - Yali Chen, Min Li, Jianjun Liu, Qian Yan, Mei Zhong, Junxi Liu, Duolong Di, Jinxia Liu. Simultaneous determination of the content of isoquinoline alkaloids in Dicranostigma leptopodum (Maxim) Fedde and the effective fractionation of the alkaloids by high-performance liquid chromatography with diode array detection.
Journal of separation science.
2015 Jan; 38(1):9-17. doi:
10.1002/jssc.201400905
. [PMID: 25330407] - Hui-Liang Zou, Hong-Yu Li, Bai-Lian Liu, Guang-Xiong Zhou. A new cytotoxic benzophenanthridine isoquinoline alkaloid from the fruits of Macleaya cordata.
Journal of Asian natural products research.
2015; 17(8):856-60. doi:
10.1080/10286020.2015.1016000
. [PMID: 25761206] - Xuelong Yu, Xiaoli Gao, Zhixiang Zhu, Yuan Cao, Qian Zhang, Pengfei Tu, Xingyun Chai. Alkaloids from the tribe Bocconieae (papaveraceae): a chemical and biological review.
Molecules (Basel, Switzerland).
2014 Aug; 19(9):13042-60. doi:
10.3390/molecules190913042
. [PMID: 25157468] - Azeana Zahari, Foo Kit Cheah, Jamaludin Mohamad, Syazreen Nadia Sulaiman, Marc Litaudon, Kok Hoong Leong, Khalijah Awang. Antiplasmodial and antioxidant isoquinoline alkaloids from Dehaasia longipedicellata.
Planta medica.
2014 May; 80(7):599-603. doi:
10.1055/s-0034-1368349
. [PMID: 24723007] - Sayaree Dhar, Dipak Kumar Rana, Arunava Pal, Subhash Chandra Bhattacharya. Photobehavior and docking simulations of drug within macromolecules: binding of an antioxidative isoquinolindione to a serine protease and albumin proteins.
Journal of photochemistry and photobiology. B, Biology.
2013 Dec; 129(?):69-77. doi:
10.1016/j.jphotobiol.2013.09.007
. [PMID: 24177206] - Hong Zhao, H Dorota Halicka, Jiangwei Li, Zbigniew Darzynkiewicz. Berberine suppresses gero-conversion from cell cycle arrest to senescence.
Aging.
2013 Aug; 5(8):623-36. doi:
10.18632/aging.100593
. [PMID: 23974852] - Asama Mukherjee, Sushanta Dutta, Utpal Sanyal. Evaluation of antitumor efficacy and toxicity of novel 6-nitro-2-(3-chloropropyl)-1H-benz[de]isoquinoline-1,3-dione in vivo in mouse.
Journal of cancer research and therapeutics.
2013 Jul; 9(3):442-6. doi:
10.4103/0973-1482.119332
. [PMID: 24125980] - Robert Domitrović, Hrvoje Jakovac, Vanja Vasiljev Marchesi, Biljana Blažeković. Resolution of liver fibrosis by isoquinoline alkaloid berberine in CCl₄-intoxicated mice is mediated by suppression of oxidative stress and upregulation of MMP-2 expression.
Journal of medicinal food.
2013 Jun; 16(6):518-28. doi:
10.1089/jmf.2012.0175
. [PMID: 23734997] - Yu Lei, Juan Tan, Michael Wink, Yonggang Ma, Na Li, Guannan Su. An isoquinoline alkaloid from the Chinese herbal plant Corydalis yanhusuo W.T. Wang inhibits P-glycoprotein and multidrug resistance-associate protein 1.
Food chemistry.
2013 Feb; 136(3-4):1117-21. doi:
10.1016/j.foodchem.2012.09.059
. [PMID: 23194502] - Fumihiko Sato, Hidehiko Kumagai. Microbial production of isoquinoline alkaloids as plant secondary metabolites based on metabolic engineering research.
Proceedings of the Japan Academy. Series B, Physical and biological sciences.
2013; 89(5):165-82. doi:
10.2183/pjab.89.165
. [PMID: 23666088] - Yit-Lai Chow, Fumihiko Sato. Screening of isoquinoline alkaloids for potent lipid metabolism modulation with Caenorhabditis elegans.
Bioscience, biotechnology, and biochemistry.
2013; 77(12):2405-12. doi:
10.1271/bbb.130523
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Annals of hepatology.
2012 Nov; 11(6):838-48. doi:
10.1016/s1665-2681(19)31408-5
. [PMID: 23109446] - Wei Zhang, Jin-Feng Hu, Wen-Wen Lv, Qing-Chun Zhao, Guo-Bing Shi. Antibacterial, antifungal and cytotoxic isoquinoline alkaloids from Litsea cubeba.
Molecules (Basel, Switzerland).
2012 Nov; 17(11):12950-60. doi:
10.3390/molecules171112950
. [PMID: 23117434] - Eduardo Sobarzo-Sánchez, Patricio González Soto, Cristóbal Valdés Rivera, Georgina Sánchez, María Eliana Hidalgo. Applied biological and physicochemical activity of isoquinoline alkaloids: oxoisoaporphine and boldine.
Molecules (Basel, Switzerland).
2012 Sep; 17(9):10958-70. doi:
10.3390/molecules170910958
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Phytotherapy research : PTR.
2012 Sep; 26(9):1342-7. doi:
10.1002/ptr.3721
. [PMID: 22294283] - Phurpa Wangchuk, Paul A Keller, Stephen G Pyne, Anthony C Willis, Sumalee Kamchonwongpaisan. Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia.
Journal of ethnopharmacology.
2012 Aug; 143(1):310-3. doi:
10.1016/j.jep.2012.06.037
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Analytica chimica acta.
2012 Aug; 737(?):99-104. doi:
10.1016/j.aca.2012.05.054
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Plant molecular biology.
2012 Aug; 79(6):569-81. doi:
10.1007/s11103-012-9929-7
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Journal of cellular biochemistry.
2012 Aug; 113(8):2785-95. doi:
10.1002/jcb.24156
. [PMID: 22473817] - K Iwasa, M Moriyasu, W Wiegrebe. Some contributions to the application of LC-NMR, LC-MS, and LC-CD to the biosynthesis of isoquinoline alkaloids using callus cultures.
Die Pharmazie.
2012 Jul; 67(7):571-85. doi:
"
. [PMID: 22888511] - Lian Chen, Martin Conda-Sheridan, P V Narasimha Reddy, Andrew Morrell, Eun-Jung Park, Tamara P Kondratyuk, John M Pezzuto, Richard B van Breemen, Mark Cushman. Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents.
Journal of medicinal chemistry.
2012 Jun; 55(12):5965-81. doi:
10.1021/jm3006806
. [PMID: 22712432] - Phurpa Wangchuk, Paul A Keller, Stephen G Pyne, Thanapat Sastraruji, Malai Taweechotipatr, Roonglawan Rattanajak, Aunchalee Tonsomboon, Sumalee Kamchonwongpaisan. Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa.
Natural product communications.
2012 May; 7(5):575-80. doi:
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- Anirban Basu, Parasuraman Jaisankar, Gopinatha Suresh Kumar. Synthesis of novel 9-O-N-aryl/aryl-alkyl amino carbonyl methyl substituted berberine analogs and evaluation of DNA binding aspects.
Bioorganic & medicinal chemistry.
2012 Apr; 20(8):2498-505. doi:
10.1016/j.bmc.2012.03.006
. [PMID: 22459209] - Wei-Han Chueh, Jin-Yuarn Lin. Protective effect of berberine on serum glucose levels in non-obese diabetic mice.
International immunopharmacology.
2012 Mar; 12(3):534-8. doi:
10.1016/j.intimp.2012.01.003
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Inorganic chemistry.
2012 Feb; 51(4):2522-32. doi:
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Journal of neuroscience research.
2012 Feb; 90(2):489-97. doi:
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BMC genomics.
2012 Jan; 13(?):9. doi:
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PloS one.
2012; 7(3):e32237. doi:
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Pharmaceutical biology.
2012 Jan; 50(1):61-71. doi:
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Bioorganic & medicinal chemistry.
2012 Jan; 20(1):34-41. doi:
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European journal of endocrinology.
2012 Jan; 166(1):99-105. doi:
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Frontiers in oncology.
2012; 2(?):58. doi:
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TheScientificWorldJournal.
2012; 2012(?):859210. doi:
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Planta medica.
2012 Jan; 78(1):65-70. doi:
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Journal of pharmacy & bioallied sciences.
2012 Jan; 4(1):10-20. doi:
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Bioorganic & medicinal chemistry letters.
2011 Dec; 21(24):7387-91. doi:
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Inflammation.
2011 Dec; 34(6):659-67. doi:
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International immunopharmacology.
2011 Nov; 11(11):1706-14. doi:
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Plant signaling & behavior.
2011 Nov; 6(11):1627-30. doi:
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Mini reviews in medicinal chemistry.
2011 Nov; 11(13):1122-9. doi:
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Journal of ethnopharmacology.
2011 Oct; 138(1):111-8. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Sep; 18(12):1045-52. doi:
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Archives of microbiology.
2011 Sep; 193(9):641-50. doi:
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The Journal of pharmacology and experimental therapeutics.
2011 Sep; 338(3):917-24. doi:
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Fitoterapia.
2011 Sep; 82(6):889-95. doi:
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Journal of chromatography. A.
2011 Aug; 1218(31):5298-304. doi:
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Journal of agricultural and food chemistry.
2011 Jul; 59(14):8021-7. doi:
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Chinese medicine.
2011 Jul; 6(1):27. doi:
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Talanta.
2011 Jul; 85(1):787-93. doi:
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Plant & cell physiology.
2011 Jul; 52(7):1131-41. doi:
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Cancer science.
2011 Jul; 102(7):1287-92. doi:
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Molecules (Basel, Switzerland).
2011 Jun; 16(7):5453-9. doi:
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Behavioural brain research.
2011 Jun; 220(1):30-41. doi:
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Organic & biomolecular chemistry.
2011 Jun; 9(11):4127-37. doi:
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Talanta.
2011 May; 84(3):684-9. doi:
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Natural product communications.
2011 May; 6(5):607-10. doi:
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Biochimica et biophysica acta.
2011 May; 1814(5):657-63. doi:
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Molecules (Basel, Switzerland).
2011 Apr; 16(4):3391-401. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2011 Apr; 18(6):533-8. doi:
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Molecular cancer.
2011 Apr; 10(?):39. doi:
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PloS one.
2011 Apr; 6(4):e18463. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2011 Apr; 49(4):799-806. doi:
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Malaria journal.
2011 Mar; 10 Suppl 1(?):S4. doi:
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