Spinasterol (BioDeep_00001867520)

Main id: BioDeep_00000000531

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(3S,5S,9R,10S,13R,14R,17R)-17-((2R,5S,E)-5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

化学式: C29H48O (412.3705)
中文名称: 菠甾醇
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-11-15.

Cite this Page

Spinasterol. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/spinasterol (retrieved 2024-12-22) (BioDeep RN: BioDeep_00001867520). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@]([H])([C@]([H])(C)/C=C/[C@@H](CC)C(C)C)CC[C@@]4([H])C3=CC[C@@]2([H])C[C@@H](O)C1
InChI: InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-9,11,19-23,25-27,30H,7,10,12-18H2,1-6H3/b9-8+/t20-,21-,22+,23+,25-,26+,27+,28+,29-/m1/s1

描述信息

Alpha-Spinasterol is a steroid. It derives from a hydride of a stigmastane.
alpha-Spinasterol is a natural product found in Pandanus utilis, Benincasa hispida, and other organisms with data available.
See also: Menyanthes trifoliata leaf (part of).
α-Spinasterol, isolated from Melandrium firmum, has antibacterial activity[1]. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively[2].
α-Spinasterol, isolated from Melandrium firmum, has antibacterial activity[1]. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively[2].

同义名列表

40 个代谢物同义名

(3S,5S,9R,10S,13R,14R,17R)-17-((2R,5S,E)-5-ethyl-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol; (3S,5S,9R,10S,13R,14R,17R)-17-[(E,2R,5S)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2-(1H-tetazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid(5-Methyl-2-oxo-1,3-dioxol-4-yl)methylester; 17-[(E)-5-ethyl-6-methylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; STIGMASTA-7,22-DIEN-3-OL, (3-.BETA.,5-.ALPHA.,22E)-; (3-.BETA.,5-.ALPHA.,22E)-STIGMASTA-7,22-DIEN-3-OL; 5-.ALPHA.-STIGMASTA-7,22-DIEN-3-.BETA.-OL, (E)-; Stigmasta-7,22-dien-3-ol, (3-beta,5-alpha,22E)-; 7,22,5alpha-Cholestadien-24beta-ethyl-3beta-ol; 24R-ethyl-5alpha-cholesta-7,22E-dien-3beta-ol; (3-beta,5-alpha,22E)-Stigmasta-7,22-dien-3-ol; (3beta,5alpha,22E)-Stigmasta-7,22-dien-3-ol; 5-alpha-Stigmasta-7,22-dien-3-beta-ol, (E)-; spinasterol, (3beta,5alpha,22E,24R)-isomer; 5.ALPHA.-STIGMASTA-7,22-DIEN-3.BETA.-OL; Stigmasta-7,22-dien-3-ol, (3b,5a,22E)-; 5-alpha-stigmasta-7,22-diene-3beta-ol; (3?,5?,22E)-Stigmasta-7.22-dien-3-ol; 5alpha-Stigmasta-7,22-dien-3beta-ol; .DELTA.7,22-STIGMASTAN-3.BETA.-OL; delta7,22-STIGMASTAN-3beta-OL; Stigmasta-7,22E-dien-3beta-ol; .ALPHA.-SPINASTEROL [MI]; .alpha.-Spinasterol; .ALPHA.-SPINASTERIN; alpha-Spinasterin; Alpha-Spinasterol; Chondrillasterol; UNII-0LG993QX1A; a-Spinasterol; ?-Spinasterol; α-Spinasterol; Hitodesterol; Bessisterol; Spinosterol; spinasterol; 0LG993QX1A; ST 29:2;O; 1ST13004; alpha-Spinasterol



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

202 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AKT1, CAT, ESR1, IRS1, MAPK14, MSMP, PPARG, PTGS2, TP53
Peripheral membrane protein 2 ESR1, PTGS2
Endoplasmic reticulum membrane 4 ABCG1, HMGCR, HMOX1, PTGS2
Nucleus 8 AKT1, ESR1, HMOX1, IRS1, MAPK14, PDX1, PPARG, TP53
cytosol 11 ACOX1, AKT1, CAT, ESR1, HMOX1, IRS1, IRS2, MAPK14, PDX1, PPARG, TP53
centrosome 1 TP53
nucleoplasm 8 AKT1, ESR1, HMOX1, IRS1, MAPK14, PDX1, PPARG, TP53
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 5 ABCG1, AKT1, ESR1, TNF, TRPV1
Cytoplasmic side 2 ESR1, HMOX1
lamellipodium 1 AKT1
Multi-pass membrane protein 3 ABCG1, HMGCR, TRPV1
Golgi apparatus membrane 1 ABCG1
cell cortex 1 AKT1
cell surface 1 TNF
glutamatergic synapse 2 AKT1, MAPK14
Golgi apparatus 2 ABCG1, ESR1
Golgi membrane 2 ABCG1, INS
neuronal cell body 2 TNF, TRPV1
postsynapse 1 AKT1
Cytoplasm, cytosol 2 IRS2, PDX1
endosome 1 ABCG1
plasma membrane 7 ABCG1, AKT1, ESR1, IRS1, IRS2, TNF, TRPV1
Membrane 9 ABCG1, ACOX1, AKT1, CAT, ESR1, HMGCR, HMOX1, TP53, TRPV1
caveola 2 IRS1, PTGS2
extracellular exosome 1 CAT
endoplasmic reticulum 4 HMGCR, HMOX1, PTGS2, TP53
extracellular space 5 HMOX1, IL6, INS, MSMP, TNF
perinuclear region of cytoplasm 2 HMOX1, PPARG
mitochondrion 5 ABCG1, CAT, MAPK14, PDX1, TP53
protein-containing complex 5 AKT1, CAT, ESR1, PTGS2, TP53
intracellular membrane-bounded organelle 3 CAT, IRS1, PPARG
Microsome membrane 1 PTGS2
Secreted 3 IL6, INS, MSMP
extracellular region 6 CAT, DNAH9, IL6, INS, MAPK14, TNF
mitochondrial outer membrane 1 HMOX1
Mitochondrion matrix 1 TP53
mitochondrial matrix 3 CAT, PDX1, TP53
transcription regulator complex 2 ESR1, TP53
motile cilium 1 DNAH9
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
external side of plasma membrane 3 ABCG1, TNF, TRPV1
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
cell-cell junction 1 AKT1
recycling endosome 2 ABCG1, TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
postsynaptic membrane 1 TRPV1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton 1 TP53
focal adhesion 1 CAT
microtubule 1 DNAH9
spindle 1 AKT1
GABA-ergic synapse 1 TRPV1
Peroxisome 2 ACOX1, CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 2 ACOX1, CAT
peroxisomal membrane 3 ACOX1, CAT, HMGCR
Nucleus, PML body 1 TP53
PML body 1 TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
axoneme 1 DNAH9
nuclear speck 2 MAPK14, PDX1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Postsynaptic cell membrane 1 TRPV1
receptor complex 1 PPARG
Cell projection, neuron projection 1 TRPV1
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 4 ESR1, PDX1, PPARG, TP53
phagocytic cup 1 TNF
spindle pole 1 MAPK14
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAH9
site of double-strand break 1 TP53
endosome lumen 1 INS
euchromatin 1 ESR1
germ cell nucleus 1 TP53
replication fork 1 TP53
Peroxisome membrane 1 HMGCR
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
pyruvate dehydrogenase complex 1 PDX1
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
9+2 motile cilium 1 DNAH9
dynein complex 1 DNAH9
Single-pass type IV membrane protein 1 HMOX1
[Isoform 1]: Nucleus 2 ESR1, TP53
Cell projection, dendritic spine membrane 1 TRPV1
dendritic spine membrane 1 TRPV1
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
insulin receptor complex 1 IRS1
outer dynein arm 1 DNAH9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
distal portion of axoneme 1 DNAH9


文献列表

  • Farid Khallouki, Mohamed Ksila, Imen Ghzaiel, Soukaina Essadek, Mounia Tahri Joutey, Samah Maaloul, Wafa Zennouhi, Laila Benbacer, Mohamed Bourhia, Lhoussain Hajji, Amira Zarrouk, Leila Rezig, Sandrine Rup-Jacques, Raoudha Abdellaoui, Taoufik Ghrairi, Olfa Masmoudi-Kouki, Boubker Nasser, Pierre Andreoletti, Mustapha-Cherkaoui-Malki, Mohammad Samadi, Anne Vejux, Gérard Lizard. Chemical and Biochemical Features of Spinasterol and Schottenol. Advances in experimental medicine and biology. 2024; 1440(?):45-55. doi: 10.1007/978-3-031-43883-7_3. [PMID: 38036874]
  • Muhammed Majeed, Furkan Ahmad, Lakshmi Mundkur, Subramoniam Appian. Pharmacology of α-spinasterol, a phytosterol with nutraceutical values: A review. Phytotherapy research : PTR. 2022 Oct; 36(10):3681-3690. doi: 10.1002/ptr.7560. [PMID: 35802356]
  • Maqsood Ahmed, Allah Rakha Sajid, Ansar Javeed, Muhammad Aslam, Taswar Ahsan, Dilbar Hussain, Abdul Mateen, Xiuwei Li, Peiwen Qin, Mingshan Ji. Antioxidant, antifungal, and aphicidal activity of the triterpenoids spinasterol and 22,23-dihydrospinasterol from leaves of Citrullus colocynthis L. Scientific reports. 2022 03; 12(1):4910. doi: 10.1038/s41598-022-08999-z. [PMID: 35318417]
  • Maqsood Ahmed, Peiwen Qin, Mingshan Ji, Ran An, Hongxia Guo, Jamil Shafi. Spinasterol, 22,23-Dihydrospinasterol and Fernenol from Citrullus Colocynthis L. with Aphicidal Activity against Cabbage Aphid Brevicoryne Brassicae L. Molecules (Basel, Switzerland). 2020 May; 25(9):. doi: 10.3390/molecules25092184. [PMID: 32392823]
  • Olamide Elizabeth Adebiyi, James Olukayode Olopade, Funsho Olakitike Olayemi. Sodium metavanadate induced cognitive decline, behavioral impairments, oxidative stress and down regulation of myelin basic protein in mice hippocampus: Ameliorative roles of β-spinasterol, and stigmasterol. Brain and behavior. 2018 07; 8(7):e01014. doi: 10.1002/brb3.1014. [PMID: 29856129]
  • Indiara Brusco, Camila Camponogara, Fabiano Barbosa Carvalho, Maria Rosa Chitolina Schetinger, Mauro Schneider Oliveira, Gabriela Trevisan, Juliano Ferreira, Sara Marchesan Oliveira. α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice. British journal of pharmacology. 2017 Dec; 174(23):4247-4262. doi: 10.1111/bph.13992. [PMID: 28849589]
  • Ivan Haralampiev, Holger A Scheidt, Daniel Huster, Peter Müller. The Potential of α-Spinasterol to Mimic the Membrane Properties of Natural Cholesterol. Molecules (Basel, Switzerland). 2017 Aug; 22(8):. doi: 10.3390/molecules22081390. [PMID: 28829376]
  • Katarzyna Socała, Piotr Wlaź. Evaluation of the antidepressant- and anxiolytic-like activity of α-spinasterol, a plant derivative with TRPV1 antagonistic effects, in mice. Behavioural brain research. 2016 Apr; 303(?):19-25. doi: 10.1016/j.bbr.2016.01.048. [PMID: 26808607]
  • Alessio Cimmino, Véronique Mathieu, Marco Evidente, Marlène Ferderin, Laetitia Moreno Y Banuls, Marco Masi, Annelise De Carvalho, Robert Kiss, Antonio Evidente. Glanduliferins A and B, two new glucosylated steroids from Impatiens glandulifera, with in vitro growth inhibitory activity in human cancer cells. Fitoterapia. 2016 Mar; 109(?):138-45. doi: 10.1016/j.fitote.2015.12.016. [PMID: 26732071]
  • Katarzyna Socała, Dorota Nieoczym, Mateusz Pieróg, Piotr Wlaź. α-Spinasterol, a TRPV1 receptor antagonist, elevates the seizure threshold in three acute seizure tests in mice. Journal of neural transmission (Vienna, Austria : 1996). 2015 Sep; 122(9):1239-47. doi: 10.1007/s00702-015-1391-7. [PMID: 25764210]
  • Asmaa Badreddine, El Mostafa Karym, Amira Zarrouk, Thomas Nury, Youssef El Kharrassi, Boubker Nasser, Mustapha Cherkaoui Malki, Gérard Lizard, Mohammad Samadi. An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system. Steroids. 2015 Jul; 99(Pt B):119-24. doi: 10.1016/j.steroids.2015.01.005. [PMID: 25595450]
  • Mee-Young Lee, In-Sik Shin, Hwangbo Kyoung, Chang-Seob Seo, Jong-Keun Son, Hyeun-Kyoo Shin. α-Spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model. Molecular medicine reports. 2014 Jun; 9(6):2362-6. doi: 10.3892/mmr.2014.2081. [PMID: 24682042]
  • Youssef El Kharrassi, Mohammad Samadi, Tatiana Lopez, Thomas Nury, Riad El Kebbaj, Pierre Andreoletti, Hammam I El Hajj, Joseph Vamecq, Khadija Moustaid, Norbert Latruffe, M'Hammed Saïd El Kebbaj, David Masson, Gérard Lizard, Boubker Nasser, Mustapha Cherkaoui-Malki. Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells. Biochemical and biophysical research communications. 2014 Apr; 446(3):798-804. doi: 10.1016/j.bbrc.2014.02.074. [PMID: 24582563]
  • Fabio R M Borges, Morgana D Silva, Marina M Córdova, Tiago R Schambach, Moacir G Pizzolatti, Adair R S Santos. Anti-inflammatory action of hydroalcoholic extract, dichloromethane fraction and steroid α-spinasterol from Polygala sabulosa in LPS-induced peritonitis in mice. Journal of ethnopharmacology. 2014; 151(1):144-50. doi: 10.1016/j.jep.2013.10.009. [PMID: 24161429]
  • Gabriela Trevisan, Mateus Fortes Rossato, Cristiani Isabel Banderó Walker, Jonatas Zeni Klafke, Fernanda Rosa, Sara Marchesan Oliveira, Raquel Tonello, Gustavo Petri Guerra, Aline Augusti Boligon, Ricardo Basso Zanon, Margareth Linde Athayde, Juliano Ferreira. Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties. The Journal of pharmacology and experimental therapeutics. 2012 Nov; 343(2):258-69. doi: 10.1124/jpet.112.195909. [PMID: 22837009]
  • Luiz C Klein-Júnior, Nicole A Meira, Tania M B Bresolin, Valdir Cechinel-Filho, Nara L M Quintão. Antihyperalgesic activity of the methanol extract and some constituents obtained from Polygala cyparissias (Polygalaceae). Basic & clinical pharmacology & toxicology. 2012 Sep; 111(3):145-53. doi: 10.1111/j.1742-7843.2012.00876.x. [PMID: 22381005]
  • Jin-Song Liu, Ai-Min Chen, Ying-Sheng Xu, Cong-Er Zhang, Gang Wang. [Study on triterpenoids from Wisteria sinensis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Aug; 35(8):1246-50. doi: . [PMID: 23320355]
  • Tae Hoon Lee, Mira Jung, Myun-Ho Bang, Dae Kyun Chung, Jiyoung Kim. Inhibitory effects of a spinasterol glycoside on lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines via down-regulating MAP kinase pathways and NF-κB activation in RAW264.7 macrophage cells. International immunopharmacology. 2012 Jul; 13(3):264-70. doi: 10.1016/j.intimp.2012.05.005. [PMID: 22595195]
  • Jun Lee, Yun Mi Lee, Byong Won Lee, Joo-Hwan Kim, Jin Sook Kim. Chemical constituents from the aerial parts of Aster koraiensis with protein glycation and aldose reductase inhibitory activities. Journal of natural products. 2012 Feb; 75(2):267-70. doi: 10.1021/np200646e. [PMID: 22264115]
  • Hyun Young Park, Hyun Lim, Hyun Pyo Kim, Yong Soo Kwon. Downregulation of matrix metalloproteinase-13 by the root extract of Cyathula officinalis Kuan and its constituents in IL-1β-treated chondrocytes. Planta medica. 2011 Sep; 77(13):1528-30. doi: 10.1055/s-0030-1270834. [PMID: 21347999]
  • Boglárka Csupor-Löffler, Zsuzsanna Hajdú, István Zupkó, Judit Molnár, Peter Forgo, Andrea Vasas, Zoltán Kele, Judit Hohmann. Antiproliferative constituents of the roots of Conyza canadensis. Planta medica. 2011 Jul; 77(11):1183-8. doi: 10.1055/s-0030-1270714. [PMID: 21294076]
  • Wen-yong Wang, Shi-cheng Zhao, Dong-xin Liu. [Study on the chemical constituents of Codonopsis lanceolata]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Apr; 34(4):553-5. doi: . [PMID: 21809542]
  • Elvia Coballase-Urrutia, José Pedraza-Chaverri, Rafael Camacho-Carranza, Noemí Cárdenas-Rodríguez, Bernardino Huerta-Gertrudis, Omar Noel Medina-Campos, Myrna Mendoza-Cruz, Guillermo Delgado-Lamas, J Javier Espinosa-Aguirre. Antioxidant activity of Heterotheca inuloides extracts and of some of its metabolites. Toxicology. 2010 Sep; 276(1):41-8. doi: 10.1016/j.tox.2010.06.013. [PMID: 20620188]
  • Shirley Boller, Cristian Soldi, Maria C A Marques, Elide P Santos, Daniela A Cabrini, Moacir G Pizzolatti, Aleksander R Zampronio, Michel F Otuki. Anti-inflammatory effect of crude extract and isolated compounds from Baccharis illinita DC in acute skin inflammation. Journal of ethnopharmacology. 2010 Jul; 130(2):262-6. doi: 10.1016/j.jep.2010.05.001. [PMID: 20452414]
  • Y S Ravikumar, K M Mahadevan, H Manjunatha, N D Satyanarayana. Antiproliferative, apoptotic and antimutagenic activity of isolated compounds from Polyalthia cerasoides seeds. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2010 Jun; 17(7):513-8. doi: 10.1016/j.phymed.2009.09.005. [PMID: 19879119]
  • Luiz Carlos Klein, Renan Becker Gandolfi, José Roberto Santin, Marivane Lemos, Valdir Cechinel Filho, Sérgio Faloni de Andrade. Antiulcerogenic activity of extract, fractions, and some compounds obtained from Polygala cyparissias St. Hillaire & Moquin (Polygalaceae). Naunyn-Schmiedeberg's archives of pharmacology. 2010 Feb; 381(2):121-6. doi: 10.1007/s00210-009-0485-x. [PMID: 20054524]
  • Cristina Setim Freitas, Cristiane Hatsuko Baggio, Ana Cristina Dos Santos, Bárbara Mayer, André Twardowschy, Ana Paula Luiz, Rodrigo Marcon, Cristian Soldi, Moacir G Pizzolatti, Elide Pereira Dos Santos, Maria Consuelo Andrade Marques, Adair R S Santos. Antinociceptive properties of the hydroalcoholic extract, fractions and compounds obtained from the aerial parts of Baccharis illinita DC in mice. Basic & clinical pharmacology & toxicology. 2009 Apr; 104(4):285-92. doi: 10.1111/j.1742-7843.2008.00367.x. [PMID: 19281601]
  • Chuan-Chung Tsao, Yuh-Chiang Shen, Chung-Ren Su, Chia-Ying Li, Meei-Jen Liou, Nguyen-Xuan Dung, Tian-Shung Wu. New diterpenoids and the bioactivity of Erythrophleum fordii. Bioorganic & medicinal chemistry. 2008 Nov; 16(22):9867-70. doi: 10.1016/j.bmc.2008.09.021. [PMID: 18926710]
  • Ke Pi, Qian-Jun Zhang, Ming-Yue Mou, Song Bai, Qing Chen, Rong-Jun Yao. [Study on liposoluble constituents of Teucrium labiosum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2008 Jul; 31(7):1003-5. doi: ". [PMID: 18973016]
  • Benoit Lefebvre, Fabienne Furt, Marie-Andrée Hartmann, Louise V Michaelson, Jean-Pierre Carde, Françoise Sargueil-Boiron, Michel Rossignol, Johnathan A Napier, Julie Cullimore, Jean-Jacques Bessoule, Sébastien Mongrand. Characterization of lipid rafts from Medicago truncatula root plasma membranes: a proteomic study reveals the presence of a raft-associated redox system. Plant physiology. 2007 May; 144(1):402-18. doi: 10.1104/pp.106.094102. [PMID: 17337521]
  • Xiao-Xiao Liu, Lei Wang, Qiang Wang, Bin Qiu. [Chemical constituents from root of Psammosilene tunicoides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 May; 32(10):921-3. doi: ". [PMID: 17655146]
  • Shun Yao, Renming Liu, Xuefeng Huang, Lingyi Kong. Preparative isolation and purification of chemical constituents from the root of Adenophora tetraphlla by high-speed counter-current chromatography with evaporative light scattering detection. Journal of chromatography. A. 2007 Jan; 1139(2):254-62. doi: 10.1016/j.chroma.2006.11.056. [PMID: 17150224]
  • Pei-dong Chen, Tu-lin Lu. [Study on the chemical constituents of Curcuma phaeocaulis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2006 Jul; 29(7):675-7. doi: ". [PMID: 17059004]
  • Flavia Carla Meotti, Juliana V Ardenghi, Juliana B Pretto, Márcia M Souza, Janaína d' Avila Moura, Anildo Cunha Junior, Cristian Soldi, Moacir Geraldo Pizzolatti, Adair R S Santos. Antinociceptive properties of coumarins, steroid and dihydrostyryl-2-pyrones from Polygala sabulosa (Polygalaceae) in mice. The Journal of pharmacy and pharmacology. 2006 Jan; 58(1):107-12. doi: 10.1211/jpp.58.1.0013. [PMID: 16393470]
  • Jing-yong Sun, Ying Zhong, Chun-xu Zuo, Jun-ting Yin, Bin Wang. [Isolation and structure identification of the chemical constituents from Gypsophila oldhamiana]. Yao xue xue bao = Acta pharmaceutica Sinica. 2005 Nov; 40(11):994-6. doi: ". [PMID: 16499082]
  • Li-Jie Zhang, Xue-Dong Yang, Li-Zhen Xu, Zhong-Mei Zou, Shi-Lin Yang. A new sterol glycoside from Securidaca inappendiculata. Journal of Asian natural products research. 2005 Aug; 7(4):649-53. doi: 10.1080/1028602032000169569. [PMID: 16087640]
  • Gook-Che Jeon, Myoung-Soon Park, Do-Young Yoon, Chul-Ho Shin, Hong-Sig Sin, Soo-Jong Um. Antitumor activity of spinasterol isolated from Pueraria roots. Experimental & molecular medicine. 2005 Apr; 37(2):111-20. doi: 10.1038/emm.2005.15. [PMID: 15886524]
  • Xiao-Ya Zhao, Han-Dong Sun, Ji-Zhou Wu. [Studies on chemical constituents from rhizome of Impatiens pritzellii var. hupehensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2005 Apr; 30(8):584-6. doi: . [PMID: 16011279]
  • Carmen S R Freire, Dora S C Coelho, Nuno M Santos, Armando J D Silvestre, Carlos Pascoal Neto. Identification of delta7 phytosterols and phytosteryl glucosides in the wood and bark of several Acacia species. Lipids. 2005 Mar; 40(3):317-22. doi: 10.1007/s11745-005-1388-y. [PMID: 15957259]
  • H M Herath, P S Athukoralage, J F Jamie. A new oleanane triterpenoid from Gordonia ceylanica. Natural product letters. 2001; 15(5):339-44. doi: 10.1080/10575630108041301. [PMID: 11841118]
  • S T Behmer, D O Elias. Sterol metabolic constraints as a factor contributing to the maintenance of diet mixing in grasshoppers (Orthoptera: Acrididae). Physiological and biochemical zoology : PBZ. 2000 Mar; 73(2):219-30. doi: 10.1086/316728. [PMID: 10801400]
  • S Yang, Y Zhong, H Luo, X Ding, C Zuo. [Studies on chemical constituents of the roots of Gypsophila oldhamiana Miq]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1999 Nov; 24(11):680-1, 703. doi: ". [PMID: 12212087]
  • L Xu, J Liu, D Min, S Wang, Z Zhang, D Guo, K Zheng. [Chemical constituents of Conyza blinii Lévl]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1998 May; 23(5):293-5, 320. doi: ". [PMID: 11601315]
  • P Ghosh, G W Patterson, G H Wikfors. Use of an improved internal-standard method in the quantitative sterol analyses of phytoplankton and oysters. Lipids. 1997 Sep; 32(9):1011-4. doi: 10.1007/s11745-997-0131-z. [PMID: 9307944]
  • S Wei, H Liang, Y Zhao, R Zhang. [Separation and identification of the compounds from Achyranthes bidentata Bl]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1997 May; 22(5):293-5, 319. doi: . [PMID: 11038963]
  • X Tang, Y Ma, P Li. [Separation and identification of the anti-inflammatory diterpene from the root cortices of Acanthopanax gracilistylus W. W. Smith]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1995 Apr; 20(4):231, 253. doi: ". [PMID: 7646793]
  • W S Chang, Y H Chang, F J Lu, H C Chiang. Inhibitory effects of phenolics on xanthine oxidase. Anticancer research. 1994 Mar; 14(2A):501-6. doi: . [PMID: 8017853]
  • A X Yuan. [Chemical constituents of Drymaria cordata]. Zhong yao tong bao (Beijing, China : 1981). 1987 Jan; 12(1):36-7. doi: ". [PMID: 2954703]
  • K Uchida, H Mizuno, K Hirota, K Takeda, N Takeuchi, Y Ishikawa. Effects of spinasterol and sitosterol on plasma and liver cholesterol levels and biliary and fecal sterol and bile acid excretions in mice. Japanese journal of pharmacology. 1983 Feb; 33(1):103-12. doi: 10.1254/jjp.33.103. [PMID: 6876509]
  • K Yasukawa, S Yamanouchi, M Takido. [Studies on the constituents in the water extracts of crude drugs. III. On the roots of Stellaria dichotoma L. var. lanceolata Bge. (author's transl)]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 1981 Jan; 101(1):64-6. doi: 10.1248/yakushi1947.101.1_64. [PMID: 7252785]