Citrinin (BioDeep_00000001855)

Main id: BioDeep_00000398496

 

human metabolite PANOMIX_OTCML-2023 Antitumor activity natural product


代谢物信息卡片


(3R-trans)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid

化学式: C13H14O5 (250.0841)
中文名称: 橘霉素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C2C(=COC(C)C2C)C(=O)C(C(=O)O)=C1O
InChI: InChI=1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,14H,1-3H3,(H,16,17)

描述信息

Citrinin is a mycotoxin originally isolated from Penicillium citrinum. It has since been found to be produced by a variety of other fungi which are found or used in the production of human foods, such as grain, cheese, sake and red pigments. Citrinin has also been found in commercial red yeast rice supplements, and also in Aspergillus niveus and Aspergillus terreus (Hugo Vanden Bossche, D.W.R. Mackenzie and G. Cauwenbergh. Aspergillus and Aspergillosis, 1987).
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess a broad spectrum of bioactivities, including antibacterial, antifungal, and potential anticancer and neuro-protective effects in vitro[1][2].

同义名列表

13 个代谢物同义名

(3R-trans)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid; (3R,4S)-8-hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-2-benzopyran-7-carboxylic acid; (3R-trans)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylate; (3R,4S)-8-Hydroxy-3,4,5-trimethyl-6-oxo-4,6-dihydro-3H-isochromene-7-carboxylic acid; (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylate; (-)-Citrinin; Antimycin; Citriain; Citrinin; NSC 186; (3R,4S)-6-hydroxy-3,4,5-trimethyl-8-oxo-3,4-dihydroisochromene-7-carboxylic acid; Citrinin



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

50 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AIMP2, BCL2, BCL2L1, CAT, CCNB1, DDIT3, HSPA5, TFDP3, TP53
Peripheral membrane protein 2 HSD17B6, NDUFA5
Endoplasmic reticulum membrane 3 BCL2, HMGCR, HSPA5
Mitochondrion membrane 1 BCL2L1
Nucleus 10 AIMP2, BCL2, CCNB1, CYC1, DDIT3, HSPA5, JUN, PDS5B, TFDP3, TP53
cytosol 9 AIMP2, BCL2, BCL2L1, CAT, CCNB1, DDIT3, HSPA5, PDS5B, TP53
centrosome 3 BCL2L1, CCNB1, TP53
nucleoplasm 5 ATP2B1, CCNB1, JUN, PDS5B, TP53
RNA polymerase II transcription regulator complex 2 DDIT3, JUN
Cell membrane 1 ATP2B1
Cytoplasmic side 1 BCL2L1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 ATP2B1, HMGCR, MT-CYB
Synapse 1 ATP2B1
cell surface 1 HSPA5
glutamatergic synapse 1 ATP2B1
mitochondrial inner membrane 4 BCL2L1, CYC1, MT-CYB, NDUFA5
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 2 AIMP2, BCL2L1
plasma membrane 3 ATP2B1, HSPA5, PIGR
synaptic vesicle membrane 2 ATP2B1, BCL2L1
Membrane 10 AIMP2, ATP2B1, BCL2, CAT, CCNB1, CYC1, HMGCR, HSPA5, MT-CYB, TP53
basolateral plasma membrane 1 ATP2B1
extracellular exosome 4 ATP2B1, CAT, HSPA5, PIGR
Lumenal side 1 HSD17B6
endoplasmic reticulum 6 BCL2, BCL2L1, HMGCR, HSD17B6, HSPA5, TP53
extracellular space 3 IL10, IL6, PIGR
mitochondrion 8 BCL2, BCL2L1, CAT, CYC1, HSPA5, MT-CYB, NDUFA5, TP53
protein-containing complex 4 BCL2, CAT, HSPA5, TP53
intracellular membrane-bounded organelle 4 ATP2B1, CAT, HSD17B6, HSPA5
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 1 PIGR
Secreted 2 IL10, IL6
extracellular region 3 CAT, IL10, IL6
Mitochondrion outer membrane 2 BCL2, BCL2L1
Single-pass membrane protein 3 BCL2, BCL2L1, CYC1
mitochondrial outer membrane 2 BCL2, BCL2L1
Mitochondrion matrix 2 BCL2L1, TP53
mitochondrial matrix 4 BCL2L1, CAT, CCNB1, TP53
transcription regulator complex 4 DDIT3, JUN, TFDP3, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 2 BCL2L1, TP53
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 2 ATP2B1, BCL2L1
Nucleus membrane 2 BCL2, BCL2L1
Bcl-2 family protein complex 2 BCL2, BCL2L1
nuclear membrane 2 BCL2, BCL2L1
nucleolus 1 TP53
midbody 1 HSPA5
Mitochondrion inner membrane 3 CYC1, MT-CYB, NDUFA5
Matrix side 1 NDUFA5
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TP53
focal adhesion 2 CAT, HSPA5
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 2 CAT, HMGCR
Nucleus, PML body 1 TP53
PML body 1 TP53
lateral plasma membrane 1 ATP2B1
Late endosome 1 DDIT3
receptor complex 1 PIGR
chromatin 5 DDIT3, JUN, PDS5B, TFDP3, TP53
cell projection 1 ATP2B1
Chromosome 1 PDS5B
spindle pole 1 CCNB1
nuclear chromosome 1 JUN
Basolateral cell membrane 1 ATP2B1
site of double-strand break 1 TP53
Melanosome 1 HSPA5
euchromatin 1 JUN
Presynaptic cell membrane 1 ATP2B1
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
Peroxisome membrane 1 HMGCR
respiratory chain complex I 1 NDUFA5
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 2 HSPA5, IL6
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
azurophil granule membrane 1 PIGR
immunological synapse 1 ATP2B1
chromosome, centromeric region 1 PDS5B
outer kinetochore 1 CCNB1
respiratory chain complex III 2 CYC1, MT-CYB
endoplasmic reticulum-Golgi intermediate compartment 1 HSPA5
[Isoform 1]: Nucleus 1 TP53
protein-DNA complex 1 DDIT3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
transcription factor AP-1 complex 1 JUN
secretory IgA immunoglobulin complex 1 PIGR
[Polymeric immunoglobulin receptor]: Cell membrane 1 PIGR
[Secretory component]: Secreted 1 PIGR
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
cyclin B1-CDK1 complex 1 CCNB1
endoplasmic reticulum chaperone complex 1 HSPA5
BAD-BCL-2 complex 1 BCL2
photoreceptor ribbon synapse 1 ATP2B1
CHOP-C/EBP complex 1 DDIT3
CHOP-ATF3 complex 1 DDIT3
CHOP-ATF4 complex 1 DDIT3
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • Dongyang Wang, Huanhuan Wang, Xuli Chen, Yanchao Xu, Wenwen He, Dan Wu, Mingxing Zuo, Weiming Zhu, Liping Wang. Five previously undescribed citrinin derivatives from the endophytic fungus Penicillium citrinum GZWMJZ-836. Phytochemistry. 2024 Apr; 220(?):114032. doi: 10.1016/j.phytochem.2024.114032. [PMID: 38369172]
  • Cong Song, Yang Zhang, Qian Zhao, Mengyao Chen, Yu Zhang, Congcong Gao, Zhenhua Jia, Shuishan Song, Junfeng Guan, Zhonglin Shang. Volatile organic compounds produced by Bacillus aryabhattai AYG1023 against Penicillium expansum causing blue mold on the Huangguan pear. Microbiological research. 2023 Oct; 278(?):127531. doi: 10.1016/j.micres.2023.127531. [PMID: 37871540]
  • Shanshan Wei, Zihuan Sang, Yanjiang Zhang, Huan Wang, Yan Chen, Hongxin Liu, Sasa Wang, Haibo Tan. Peniciriols A and B, two new citrinin derivatives from an endophytic fungus Penicillum citrinum TJNZ-27. Fitoterapia. 2023 Sep; 169(?):105572. doi: 10.1016/j.fitote.2023.105572. [PMID: 37315718]
  • Changrong Lai, Danmei Tian, Mingxin Zheng, Binglei Li, Jia Jia, Jihua Wei, Bin Wu, Hongkai Bi, Jinshan Tang. Novel citrinin derivatives from fungus Penicillium sp. TW131-64 and their antimicrobial activities. Applied microbiology and biotechnology. 2023 Aug; ?(?):. doi: 10.1007/s00253-023-12738-3. [PMID: 37642717]
  • Yanling Gui, Guangfu Tang, Haiqiao Man, Jiao Wang, Jie Han, Jiehong Zhao. Transportation of citrinin is regulated by the CtnC gene in the medicinal fungus Monascus purpureus. Journal of Zhejiang University. Science. B. 2023 Jun; 24(6):543-548. doi: 10.1631/jzus.b2300023. [PMID: 37309046]
  • Guangfu Tang, Haiqiao Man, Jiao Wang, Jie Zou, Jiehong Zhao, Jie Han. An oxidoreductase gene CtnD involved in citrinin biosynthesis in Monascus purpureus verified by CRISPR/Cas9 gene editing and overexpression. Mycotoxin research. 2023 Jun; ?(?):. doi: 10.1007/s12550-023-00491-5. [PMID: 37269452]
  • Qian Yang, Yanjing Guo, He Wang, Zhi Luo, Ying Chen, Mengyun Jiang, Huan Lu, Bernal E Valverde, Sheng Qiang, Reto Jörg Strasser, Shiguo Chen. Action of the fungal compound citrinin, a bioherbicide candidate, on photosystem II. Pest management science. 2023 Apr; ?(?):. doi: 10.1002/ps.7513. [PMID: 37103431]
  • Z A Chalyy, M G Kiseleva, I B Sedova, V A Tutelyan. [Mycotoxins in spices consumed in Russia]. Voprosy pitaniia. 2023; 92(2):26-34. doi: 10.33029/0042-8833-2023-92-2-26-34. [PMID: 37346017]
  • Jihua Wei, Xuexia Chen, Yichao Ge, Qizhao Yin, Xiaodan Wu, Jinshan Tang, Zunjing Zhang, Bin Wu. Citrinin Monomer, Trimer, and Tetracyclic Alkaloid Derivatives from the Hydrothermal Vent-Associated Fungus Penicillium citrinum TW132-59. The Journal of organic chemistry. 2022 10; 87(19):13270-13279. doi: 10.1021/acs.joc.2c01856. [PMID: 36131357]
  • Carla Teresinha Endres, Graziela Vargas Rigo, Luciana Angelo Loges, Melissa Fontes Landell, Denise Brentan Silva, Alexandre José Macedo, Tiana Tasca. Mass Spectrometry Metabolomics Approach Reveals Anti-Trichomonas vaginalis Scaffolds from Marine Fungi. Marine biotechnology (New York, N.Y.). 2022 Oct; 24(5):1014-1022. doi: 10.1007/s10126-022-10164-6. [PMID: 36102994]
  • Huan Chen, Jianwen Teng, Baoyao Wei, Ning Xia, Zhongyu Li, Li Huang. Development and evaluation of a qPCR detection method for citrinin in Liupao tea. Analytical biochemistry. 2022 Sep; 653(?):114771. doi: 10.1016/j.ab.2022.114771. [PMID: 35660508]
  • Nicholas N A Kyei, Benedikt Cramer, Hans-Ulrich Humpf, Gisela H Degen, Nurshad Ali, Sabine Gabrysch. Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh. Archives of toxicology. 2022 07; 96(7):2123-2138. doi: 10.1007/s00204-022-03288-0. [PMID: 35441239]
  • Alexandra Jaus, Peter Rhyn, Max Haldimann, Beat J Brüschweiler, Céline Fragnière Rime, Judith Jenny-Burri, Otmar Zoller. Biomonitoring of ochratoxin A, 2'R-ochratoxin A and citrinin in human blood serum from Switzerland. Mycotoxin research. 2022 May; 38(2):147-161. doi: 10.1007/s12550-022-00456-0. [PMID: 35446004]
  • Anan Liu, Amanda Juan Chen, Bingyu Liu, Qian Wei, Jian Bai, Youcai Hu. Investigation of citrinin and monacolin K gene clusters variation among pigment producer Monascus species. Fungal genetics and biology : FG & B. 2022 05; 160(?):103687. doi: 10.1016/j.fgb.2022.103687. [PMID: 35315337]
  • Dubravka Rašić, Srđan Stefanović, Dragan Milićević, Marin Mladinić, Davor Želježić, Alica Pizent, Paško Konjevoda, Maja Peraica. Ochratoxin A potentiates citrinin accumulation in kidney and liver of rats. Arhiv za higijenu rada i toksikologiju. 2022 Apr; 73(1):43-47. doi: 10.2478/aiht-2022-73-3605. [PMID: 35390240]
  • José Williams Gomes de Oliveira Filho, Teresinha de Jesus Aguiar Dos Santos Andrade, Rosália Maria Tôrres de Lima, Dulce Helena Siqueira Silva, Antonielly Campinho Dos Reis, José Victor de Oliveira Santos, Ag-Anne Pereira Melo de Meneses, Ricardo Melo de Carvalho, Ana Maria Oliveira da Mata, Marcus Vinícius Oliveira Barros de Alencar, Ana Carolina Soares Dias, Felipe Cavalcanti Carneiro da Silva, Muhammad Torequl Islam, Cain C T Clark, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante. Cytogenotoxic evaluation of the acetonitrile extract, citrinin and dicitrinin-A from Penicillium citrinum. Drug and chemical toxicology. 2022 Mar; 45(2):688-697. doi: 10.1080/01480545.2020.1769642. [PMID: 32448000]
  • Dean Karaica, Vedran Micek, Dubravka Rašić, Maja Peraica, Maja Šegvić Klarić, Davorka Breljak. Subchronic exposure of individual and combined ochratoxin A and citrinin selectively affects the expression of rat renal organic cation transporters. Mycotoxin research. 2022 Feb; 38(1):61-70. doi: 10.1007/s12550-022-00450-6. [PMID: 35028911]
  • Song Zhang, Xiaofang Zeng, Qinlu Lin, Jun Liu. Analysis of secondary metabolite gene clusters and chitin biosynthesis pathways of Monascus purpureus with high production of pigment and citrinin based on whole-genome sequencing. PloS one. 2022; 17(6):e0263905. doi: 10.1371/journal.pone.0263905. [PMID: 35648754]
  • Dilek Çavuşoğlu. Powerful toxic activity of citrinin, a fungal phytotoxin, and its mode of action in onion cells. Environmental science and pollution research international. 2022 Jan; 29(4):6205-6218. doi: 10.1007/s11356-021-16009-4. [PMID: 34448135]
  • Chibundu N Ezekiel, Wilfred A Abia, Dominik Braun, Bojan Šarkanj, Kolawole I Ayeni, Oluwawapelumi A Oyedele, Emmanuel C Michael-Chikezie, Victoria C Ezekiel, Beatrice N Mark, Chinonso P Ahuchaogu, Rudolf Krska, Michael Sulyok, Paul C Turner, Benedikt Warth. Mycotoxin exposure biomonitoring in breastfed and non-exclusively breastfed Nigerian children. Environment international. 2022 01; 158(?):106996. doi: 10.1016/j.envint.2021.106996. [PMID: 34991256]
  • Da-Ae Kwon, Yong Sang Kim, Seul-Ki Kim, Sin Hwa Baek, Hyun Kyu Kim, Hak Sung Lee. Antioxidant and antifatigue effect of a standardized fraction (HemoHIM) from Angelica gigas, Cnidium officinale, and Paeonia lactiflora. Pharmaceutical biology. 2021 Dec; 59(1):391-400. doi: 10.1080/13880209.2021.1900878. [PMID: 33813987]
  • Zsolt Csenki, Edina Garai, Zelma Faisal, Rita Csepregi, Kitti Garai, Dóra Kánainé Sipos, István Szabó, Tamás Kőszegi, Árpád Czéh, Tamás Czömpöly, Krisztián Kvell, Miklós Poór. The individual and combined effects of ochratoxin A with citrinin and their metabolites (ochratoxin B, ochratoxin C, and dihydrocitrinone) on 2D/3D cell cultures, and zebrafish embryo models. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2021 Dec; 158(?):112674. doi: 10.1016/j.fct.2021.112674. [PMID: 34800554]
  • Agnieszka Tkaczyk, Piotr Jedziniak, Łukasz Zielonka, Michał Dąbrowski, Piotr Ochodzki, Adrianna Rudawska. Biomarkers of Deoxynivalenol, Citrinin, Ochratoxin A and Zearalenone in Pigs after Exposure to Naturally Contaminated Feed Close to Guidance Values. Toxins. 2021 10; 13(11):. doi: 10.3390/toxins13110750. [PMID: 34822534]
  • Alfonso Narváez, Luana Izzo, Yelko Rodríguez-Carrasco, Alberto Ritieni. Citrinin Dietary Exposure Assessment Approach through Human Biomonitoring High-Resolution Mass Spectrometry-Based Data. Journal of agricultural and food chemistry. 2021 Jun; 69(22):6330-6338. doi: 10.1021/acs.jafc.1c01776. [PMID: 34060319]
  • Emmanuel K Tangni, François Van Hove, Bart Huybrechts, Julien Masquelier, Karine Vandermeiren, Els Van Hoeck. Citrinin Determination in Food and Food Supplements by LC-MS/MS: Development and Use of Reference Materials in an International Collaborative Study. Toxins. 2021 03; 13(4):. doi: 10.3390/toxins13040245. [PMID: 33808320]
  • Hongyin Zhang, Joseph Ahima, Qiya Yang, Lina Zhao, Xiaoyun Zhang, Xiangfeng Zheng. A review on citrinin: Its occurrence, risk implications, analytical techniques, biosynthesis, physiochemical properties and control. Food research international (Ottawa, Ont.). 2021 03; 141(?):110075. doi: 10.1016/j.foodres.2020.110075. [PMID: 33641962]
  • Ying Xu, Biao Ma, Erjing Chen, Xiaoping Yu, Zihong Ye, Chuanxin Sun, Mingzhou Zhang. Dual fluorescent immunochromatographic assay for simultaneous quantitative detection of citrinin and zearalenone in corn samples. Food chemistry. 2021 Jan; 336(?):127713. doi: 10.1016/j.foodchem.2020.127713. [PMID: 32768909]
  • Ivana Spevakova, Maria-Luisa Fernandez-Cruz, Katarina Tokarova, Hana Greifova, Marcela Capcarova. The protective effect of stilbenes resveratrol and pterostilbene individually and combined with mycotoxin citrinin in human adenocarcinoma HT-29 cell line in vitro. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2021; 56(1):75-88. doi: 10.1080/10934529.2020.1839279. [PMID: 33112704]
  • Magdalena Twarużek, Robert Kosicki, Justyna Kwiatkowska-Giżyńska, Jan Grajewski, Iwona Ałtyn. Ochratoxin A and citrinin in green coffee and dietary supplements with green coffee extract. Toxicon : official journal of the International Society on Toxinology. 2020 Dec; 188(?):172-177. doi: 10.1016/j.toxicon.2020.10.021. [PMID: 33096150]
  • Celine Meerpoel, Arnau Vidal, Emmanuel K Tangni, Bart Huybrechts, Liesbeth Couck, Riet De Rycke, Lobke De Bels, Sarah De Saeger, Wim Van den Broeck, Mathias Devreese, Siska Croubels. A Study of Carry-Over and Histopathological Effects after Chronic Dietary Intake of Citrinin in Pigs, Broiler Chickens and Laying Hens. Toxins. 2020 11; 12(11):. doi: 10.3390/toxins12110719. [PMID: 33207646]
  • Nurshad Ali, Gisela H Degen. Biological monitoring for ochratoxin A and citrinin and their metabolites in urine samples of infants and children in Bangladesh. Mycotoxin research. 2020 Nov; 36(4):409-417. doi: 10.1007/s12550-020-00407-7. [PMID: 32820428]
  • Dean Karaica, Vedran Micek, Dubravka Rašić, Maja Peraica, Maja Šegvić Klarić, Davorka Breljak. Subchronic exposure to individual and combined ochratoxin A and citrinin affects the expression of rat renal organic anion transporters. Mycotoxin research. 2020 Nov; 36(4):339-352. doi: 10.1007/s12550-020-00399-4. [PMID: 32653990]
  • Sanka N Atapattu, Colin F Poole. Recent advances in analytical methods for the determination of citrinin in food matrices. Journal of chromatography. A. 2020 Sep; 1627(?):461399. doi: 10.1016/j.chroma.2020.461399. [PMID: 32823104]
  • Pankaj Ramji Jagdale, Indra Dev, Anjaneya Ayanur, Dhirendra Singh, Md Arshad, Kausar Mahmood Ansari. Safety evaluation of Ochratoxin A and Citrinin after 28 days repeated dose oral exposure to Wistar rats. Regulatory toxicology and pharmacology : RTP. 2020 Aug; 115(?):104700. doi: 10.1016/j.yrtph.2020.104700. [PMID: 32525063]
  • Ya-Ping Huang, Ping Li, Ting Du, Xin-Jun Du, Shuo Wang. Protective effect and mechanism of Monascus-fermented red yeast rice against colitis caused by Salmonella enterica serotype Typhimurium ATCC 14028. Food & function. 2020 Jul; 11(7):6363-6375. doi: 10.1039/d0fo01017k. [PMID: 32609139]
  • Celine Meerpoel, Arnau Vidal, Bart Huybrechts, Emmanuel K Tangni, Sarah De Saeger, Siska Croubels, Mathias Devreese. Comprehensive toxicokinetic analysis reveals major interspecies differences in absorption, distribution and elimination of citrinin in pigs and broiler chickens. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2020 Jul; 141(?):111365. doi: 10.1016/j.fct.2020.111365. [PMID: 32320715]
  • Liliana Silva, André Pereira, Sofia Duarte, Angelina Pena, Celeste Lino. Reviewing the Analytical Methodologies to Determine the Occurrence of Citrinin and its Major Metabolite, Dihydrocitrinone, in Human Biological Fluids. Molecules (Basel, Switzerland). 2020 Jun; 25(12):. doi: 10.3390/molecules25122906. [PMID: 32599786]
  • Salma Ouhibi, Arnau Vidal, Carla Martins, Ridha Gali, Abderrazzek Hedhili, Sarah De Saeger, Marthe De Boevre. LC-MS/MS methodology for simultaneous determination of patulin and citrinin in urine and plasma applied to a pilot study in colorectal cancer patients. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2020 Feb; 136(?):110994. doi: 10.1016/j.fct.2019.110994. [PMID: 31783110]
  • Nurshad Ali, Gisela H Degen. Citrinin biomarkers: a review of recent data and application to human exposure assessment. Archives of toxicology. 2019 11; 93(11):3057-3066. doi: 10.1007/s00204-019-02570-y. [PMID: 31501918]
  • Frantisek Malir, Miroslav Louda, Vladimir Ostry, Jakub Toman, Nurshad Ali, Yann Grosse, Eva Malirova, Jaroslav Pacovsky, Darina Pickova, Milos Brodak, Annie Pfohl-Leszkowicz, Gisela H Degen. Analyses of biomarkers of exposure to nephrotoxic mycotoxins in a cohort of patients with renal tumours. Mycotoxin research. 2019 Nov; 35(4):391-403. doi: 10.1007/s12550-019-00365-9. [PMID: 31254204]
  • Erjing Chen, Ying Xu, Biao Ma, Haifeng Cui, Chuanxin Sun, Mingzhou Zhang. Carboxyl-Functionalized, Europium Nanoparticle-Based Fluorescent Immunochromatographic Assay for Sensitive Detection of Citrinin in Monascus Fermented Food. Toxins. 2019 10; 11(10):. doi: 10.3390/toxins11100605. [PMID: 31627364]
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