Isochlorogenic acid b (BioDeep_00000180138)

   

human metabolite blood metabolite natural product


代谢物信息卡片


3,4-bis({[3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-1,5-dihydroxycyclohexane-1-carboxylic acid

  化学式: C25H24O12 (516.1268)
中文名称:
  谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: O=C(C=Cc1ccc(O)c(O)c1)OC1CC(O)(C(=O)O)CC(O)C1OC(=O)C=Cc1ccc(O)c(O)c1
InChI: InChI=1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(35,24(33)34)11-19(30)23(20)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,35H,11-12H2,(H,33,34)


描述信息

同义名列表

10 个代谢物同义名

3,4-bis({[3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-1,5-dihydroxycyclohexane-1-carboxylic acid; 3,4-Bis({[3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-1,5-dihydroxycyclohexane-1-carboxylate; methyl 3,5-di-O-caffeoyl quinate; methyl-3,5-di-O-caffeoylquinate; 3,4-di-O-caffeoylquinic acid; 3,4-dicaffeoylquinic acid; isochlorogenic acid B; Isochlorogenate b; Isochlorogenate C; 3,4-DICQA



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

135 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 BCL2, CASP3, CASP9, CAT, HIF1A, PTGS2, RB1, RPS15, RPS2, TRPV3
Peripheral membrane protein 1 PTGS2
Endoplasmic reticulum membrane 3 BCL2, HMOX1, PTGS2
Nucleus 10 BCL2, CASP3, CASP9, GABPA, HIF1A, HMOX1, JUND, RB1, RPS15, RPS2
cytosol 9 BCL2, CASP3, CASP9, CAT, HIF1A, HMOX1, RB1, RPS15, RPS2
nuclear body 1 HIF1A
nucleoplasm 8 CASP3, GABPA, HIF1A, HMOX1, JUND, RB1, RPS15, RPS2
RNA polymerase II transcription regulator complex 2 HIF1A, JUND
Cell membrane 2 TNF, TRPV3
Cytoplasmic side 1 HMOX1
Multi-pass membrane protein 1 TRPV3
Synapse 1 RPS15
cell surface 1 TNF
glutamatergic synapse 1 CASP3
Golgi membrane 1 INS
neuronal cell body 2 CASP3, TNF
Lysosome 1 TRPV3
plasma membrane 2 TNF, TRPV3
Membrane 6 BCL2, CAT, HMOX1, RPS15, RPS2, TRPV3
axon 1 CCK
caveola 1 PTGS2
extracellular exosome 3 CAT, MGP, RPS2
endoplasmic reticulum 3 BCL2, HMOX1, PTGS2
extracellular space 6 CCK, HMOX1, IL17A, IL6, INS, TNF
perinuclear region of cytoplasm 1 HMOX1
mitochondrion 3 BCL2, CASP9, CAT
protein-containing complex 5 BCL2, CASP9, CAT, HIF1A, PTGS2
intracellular membrane-bounded organelle 1 CAT
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Secreted 4 CCK, IL17A, IL6, INS
extracellular region 6 CAT, CCK, IL17A, IL6, INS, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
mitochondrial matrix 1 CAT
transcription regulator complex 1 JUND
motile cilium 1 HIF1A
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 IL17A, TNF
axon cytoplasm 1 HIF1A
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
focal adhesion 3 CAT, RPS15, RPS2
spindle 1 RB1
extracellular matrix 1 MGP
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
PML body 1 RB1
collagen-containing extracellular matrix 1 MGP
nuclear speck 1 HIF1A
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 1 TRPV3
neuron projection 1 PTGS2
chromatin 4 GABPA, HIF1A, JUND, RB1
phagocytic cup 1 TNF
Nucleus, nucleolus 1 RPS2
endosome lumen 1 INS
Nucleus speckle 1 HIF1A
euchromatin 1 HIF1A
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 CAT, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 IL6, INS, PTGS2
transcription repressor complex 1 JUND
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
SWI/SNF complex 1 RB1
Single-pass type IV membrane protein 1 HMOX1
apoptosome 1 CASP9
ribonucleoprotein complex 1 RPS15
death-inducing signaling complex 1 CASP3
cytosolic ribosome 2 RPS15, RPS2
ribosome 2 RPS15, RPS2
transcription factor AP-1 complex 1 JUND
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
chromatin lock complex 1 RB1
Rb-E2F complex 1 RB1
cytosolic small ribosomal subunit 2 RPS15, RPS2
BAD-BCL-2 complex 1 BCL2
caspase complex 1 CASP9
small ribosomal subunit 2 RPS15, RPS2
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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  • Magdy M D Mohammed, Elham A Heikal, Fatma M Ellessy, Tarek Aboushousha, Mosad A Ghareeb. Comprehensive chemical profiling of Bassia indica Wight. aerial parts extract using UPLC-ESI-MS/MS, and its antiparasitic activity in Trichinella spiralis infected mice: in silico supported in vivo study. BMC complementary medicine and therapies. 2023 May; 23(1):161. doi: 10.1186/s12906-023-03988-9. [PMID: 37202749]
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  • Chung-Fan Hsieh, Yu-Li Chen, Guan-Hua Lin, Yoke Fun Chan, Pei-Wen Hsieh, Jim-Tong Horng. 3,4-Dicaffeoylquinic Acid from the Medicinal Plant Ilex kaushue Disrupts the Interaction Between the Five-Fold Axis of Enterovirus A-71 and the Heparan Sulfate Receptor. Journal of virology. 2022 04; 96(7):e0054221. doi: 10.1128/jvi.00542-21. [PMID: 35319229]
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