Applaud (BioDeep_00000176876)
human metabolite blood metabolite
代谢物信息卡片
2-Tert-butylimino-3-isopropyl-5-phenyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazin-4-one
化学式: C16H23N3OS (305.1562)
中文名称: 甲醇中噻嗪酮溶液, 噻嗪酮
谱图信息:
最多检出来源 Homo sapiens(blood) 83.33%
分子结构信息
SMILES: CC(C)N1C(=NC(C)(C)C)SCN(C1=O)C2=CC=CC=C2
InChI: InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:39381
- ChEBI: CHEBI:39380
- ChEBI: CHEBI:3218
- PubChem: 50367
- HMDB: HMDB0249444
- ChEMBL: CHEMBL1891512
- ChEMBL: CHEMBL3186631
- CAS: 953030-84-7
- CAS: 69327-76-0
- KEGG: C10912
- PubChem: 13095
- KNApSAcK: 3218
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Huiya Pan, Bo Song, Jiajie Liao, Yixi Zhang, Zewen Liu. Buprofezin delayed the molting of Pardosa pseudoannulata, a predatory enemy for insect pests, by suppressing chitin synthase 1 expression.
Pesticide biochemistry and physiology.
2024 Feb; 199(?):105798. doi:
10.1016/j.pestbp.2024.105798. [PMID: 38458668] - Gui-Yun Long, Ming-Fu Gong, Hong Yang, Xi-Bin Yang, Cao Zhou, Dao-Chao Jin. Buprofezin affects the molting process by regulating nuclear receptors SfHR3 and SfHR4 in Sogatella furcifera.
Pesticide biochemistry and physiology.
2023 Dec; 197(?):105695. doi:
10.1016/j.pestbp.2023.105695. [PMID: 38072550] - Bin Zeng, Fan Zhang, Ya-Ting Liu, Shun-Fan Wu, Chris Bass, Cong-Fen Gao. Symbiotic bacteria confer insecticide resistance by metabolizing buprofezin in the brown planthopper, Nilaparvata lugens (Stål).
PLoS pathogens.
2023 Dec; 19(12):e1011828. doi:
10.1371/journal.ppat.1011828. [PMID: 38091367] - Wael M Khamis, Said I Behiry, Samy A Marey, Abdulaziz A Al-Askar, Ghoname Amer, Ahmed A Heflish, Yiming Su, Ahmed Abdelkhalek, Mohamed K Gaber. Phytochemical analysis and insight into insecticidal and antifungal activities of Indian hawthorn leaf extract.
Scientific reports.
2023 Oct; 13(1):17194. doi:
10.1038/s41598-023-43749-9. [PMID: 37821483] - Antonio Masetti, Anna Rathé, Nicola Robertson, Diane Anderson, Jim Walker, Edison Pasqualini, Laura Depalo. Effects of three chitin synthesis inhibitors on egg masses, nymphs and adults of Halyomorpha halys (Hemiptera: Pentatomidae).
Pest management science.
2023 Mar; ?(?):. doi:
10.1002/ps.7465. [PMID: 36944039] - Vahideh Mahdavi, Sharaf S Omar, Tayebeh Zeinali, Parisa Sadighara, Yadolah Fakhri. Carcinogenic and non-carcinogenic risk assessment induced by pesticide residues in fresh pistachio in Iran based on Monte Carlo simulation.
Environmental science and pollution research international.
2023 Jan; ?(?):. doi:
10.1007/s11356-023-25143-0. [PMID: 36626050] - M A Mahmoud, I E AbdElrahman, O A A Zedan, Y A Abdel-Rahman, R M Saba, G F Abo Laban, I S Ibrahim. Effect of three insect growth regulators on certain biological aspects of the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrichidae).
Brazilian journal of biology = Revista brasleira de biologia.
2023; 82(?):e267629. doi:
10.1590/1519-6984.267629. [PMID: 36651458] - Bin Zeng, Ya-Ting Liu, Wen-Jing Zhang, Ze-Rui Feng, Shun-Fan Wu, Cong-Fen Gao. Inheritance and fitness cost of buprofezin resistance in a near-isogenic, field-derived strain and insecticide resistance monitoring of Laodelphax striatellus in China.
Pest management science.
2022 May; 78(5):1833-1841. doi:
10.1002/ps.6801. [PMID: 35048493] - Jinghan Yang, Jianguo Feng, Kangli He, Zhiyang Chen, Wang Chen, Hongen Cao, Shuzhong Yuan. Preparation of thermosensitive buprofezin-loaded mesoporous silica nanoparticles by the sol-gel method and their application in pest control.
Pest management science.
2021 Oct; 77(10):4627-4637. doi:
10.1002/ps.6502. [PMID: 34087044] - Muhammad Dildar Gogi, Ali Hassan Syed, Bilal Atta, Muhammad Sufyan, Muhammad Jalal Arif, Muhammad Arshad, Ahmad Nawaz, Muhammad Ahsan Khan, Adeel Mukhtar, Oscar Emanuel Liburd. Efficacy of biorational insecticides against Bemisia tabaci (Genn.) and their selectivity for its parasitoid Encarsia formosa Gahan on Bt cotton.
Scientific reports.
2021 01; 11(1):2101. doi:
10.1038/s41598-021-81585-x. [PMID: 33483556] - Soudamini Mohapatra, Lekha Siddamallaiah, Nagapooja Yogendraiah Matadha, Shambulinga Gadigeppa, Danish Poothotathil Raja, Veena Rao Udupi. Persistence and dissipation study of azoxystrobin, buprofezin, dinocap and hexaconazole on mango (Mangifera indica L.).
Environmental science and pollution research international.
2020 Sep; 27(26):32820-32828. doi:
10.1007/s11356-020-09557-8. [PMID: 32519101] - Yongteng Li, Xiangdong Liu, Na Wang, Yueliang Zhang, Ary A Hoffmann, Huifang Guo. Background-dependent Wolbachia-mediated insecticide resistance in Laodelphax striatellus.
Environmental microbiology.
2020 07; 22(7):2653-2663. doi:
10.1111/1462-2920.14974. [PMID: 32128956] - Razia Bibi, Irfan Zia Qureshi. Short-term exposure of Balb/c mice to buprofezin insecticide induces biochemical, enzymatic, histopathologic and genotoxic damage in liver and kidney tissues.
Toxicology mechanisms and methods.
2019 Oct; 29(8):587-603. doi:
10.1080/15376516.2019.1631924. [PMID: 31199169] - Farman Ullah, Hina Gul, Hafiz Kamran Yousaf, Wang Xiu, Ding Qian, Xiwu Gao, Kaleem Tariq, Peng Han, Nicolas Desneux, Dunlun Song. Impact of low lethal concentrations of buprofezin on biological traits and expression profile of chitin synthase 1 gene (CHS1) in melon aphid, Aphis gossypii.
Scientific reports.
2019 08; 9(1):12291. doi:
10.1038/s41598-019-48199-w. [PMID: 31444364] - Ehsan Ali, Kaikai Mao, Xun Liao, Ruoheng Jin, Jianhong Li. Cross-resistance and biochemical characterization of buprofezin resistance in the white-backed planthopper, Sogatella furcifera (Horvath).
Pesticide biochemistry and physiology.
2019 Jul; 158(?):47-53. doi:
10.1016/j.pestbp.2019.04.008. [PMID: 31378360] - Osama Abdallah, Moustafa El Agamy, Ehab Abdelraheem, Farag Malhat. Buprofezin dissipation and safety assessment in open field cabbage and cauliflower using GC/ITMS employing an analyte protectant.
Biomedical chromatography : BMC.
2019 Jun; 33(6):e4492. doi:
10.1002/bmc.4492. [PMID: 30673143] - Falin He, Shiang Sun, Xiao Sun, Shoumin Ji, Xiangdong Li, Jiwang Zhang, Xingyin Jiang. Effects of insect growth-regulator insecticides on the immature stages of Harmonia axyridis (Coleoptera: Coccinellidae).
Ecotoxicology and environmental safety.
2018 Nov; 164(?):665-674. doi:
10.1016/j.ecoenv.2018.08.076. [PMID: 30170315] - Yongteng Li, Xiangdong Liu, Huifang Guo. Variations in Endosymbiont Infection Between Buprofezin-Resistant and Susceptible Strains of Laodelphax striatellus (Fallén).
Current microbiology.
2018 Jun; 75(6):709-715. doi:
10.1007/s00284-018-1436-x. [PMID: 29569154] - Vivek Kumar, Antonio Francis, Pasco B Avery, Cindy L McKenzie, Lance S Osborne. Assessing Compatibility of Isaria fumosorosea and Buprofezin for Mitigation of Aleurodicus rugioperculatus (Hemiptera: Aleyrodidae): An Invasive Pest in the Florida Landscape.
Journal of economic entomology.
2018 05; 111(3):1069-1079. doi:
10.1093/jee/toy056. [PMID: 29546290] - Yueliang Zhang, Yangchun Han, Qiong Yang, Lihua Wang, Peng He, Zewen Liu, Zhong Li, Huifang Guo, Jichao Fang. Resistance to cycloxaprid in Laodelphax striatellus is associated with altered expression of nicotinic acetylcholine receptor subunits.
Pest management science.
2018 Apr; 74(4):837-843. doi:
10.1002/ps.4757. [PMID: 28991400] - Madiha Ghazanfar, Sana Shahid, Irfan Zia Qureshi. Vitamin C attenuates biochemical and genotoxic damage in common carp (Cyprinus carpio) upon joint exposure to combined toxic doses of fipronil and buprofezin insecticides.
Aquatic toxicology (Amsterdam, Netherlands).
2018 Mar; 196(?):43-52. doi:
10.1016/j.aquatox.2017.12.015. [PMID: 29331520] - Ehsan Ali, Xun Liao, Peng Yang, Kaikai Mao, Xiaolei Zhang, Muhammad Shakeel, Abdalla M A Salim, Hu Wan, Jianhong Li. Sublethal effects of buprofezin on development and reproduction in the white-backed planthopper, Sogatella furcifera (Hemiptera: Delphacidae).
Scientific reports.
2017 12; 7(1):16913. doi:
10.1038/s41598-017-17190-8. [PMID: 29209084] - Mohammed Esmail Abdalla Elzaki, Mohammad Asaduzzaman Miah, Zhaojun Han. Buprofezin Is Metabolized by CYP353D1v2, a Cytochrome P450 Associated with Imidacloprid Resistance in Laodelphax striatellus.
International journal of molecular sciences.
2017 Nov; 18(12):. doi:
10.3390/ijms18122564. [PMID: 29186030] - Yueliang Zhang, Yangchun Han, Baosheng Liu, Qiong Yang, Huifang Guo, Zewen Liu, Lihua Wang, Jichao Fang. Resistance monitoring and cross-resistance role of CYP6CW1 between buprofezin and pymetrozine in field populations of Laodelphax striatellus (Fallén).
Scientific reports.
2017 11; 7(1):14639. doi:
10.1038/s41598-017-15294-9. [PMID: 29116195] - Yongteng Li, Yueliang Zhang, Xiangdong Liu, Huifang Guo. Does Resistance to Buprofezin Improve Heat and Cold Tolerance of Laodelphax striatellus (Hemiptera: Delphacidae)?.
Environmental entomology.
2017 08; 46(4):988-994. doi:
10.1093/ee/nvx101. [PMID: 28595288] - Q L Wang, T-X Liu. Effects of Three Insect Growth Regulators on Encarsia formosa (Hymenoptera: Aphelinidae), an Endoparasitoid of Bemisia tabaci (Hemiptera: Aleyrodidae).
Journal of economic entomology.
2016 Dec; 109(6):2290-2297. doi:
10.1093/jee/tow216. [PMID: 27744284] - Xi-Chao Mu, Wei Zhang, Li-Xiang Wang, Shuai Zhang, Kai Zhang, Cong-Fen Gao, Shun-Fan Wu. Resistance monitoring and cross-resistance patterns of three rice planthoppers, Nilaparvata lugens, Sogatella furcifera and Laodelphax striatellus to dinotefuran in China.
Pesticide biochemistry and physiology.
2016 Nov; 134(?):8-13. doi:
10.1016/j.pestbp.2016.05.004. [PMID: 27914544] - Irfan Zia Qureshi, Asia Bibi, Sana Shahid, Madiha Ghazanfar. Exposure to sub-acute doses of fipronil and buprofezin in combination or alone induces biochemical, hematological, histopathological and genotoxic damage in common carp (Cyprinus carpio L.).
Aquatic toxicology (Amsterdam, Netherlands).
2016 Oct; 179(?):103-14. doi:
10.1016/j.aquatox.2016.08.012. [PMID: 27595653] - Xiaolei Zhang, Xun Liao, Kaikai Mao, Kaixiong Zhang, Hu Wan, Jianhong Li. Insecticide resistance monitoring and correlation analysis of insecticides in field populations of the brown planthopper Nilaparvata lugens (stål) in China 2012-2014.
Pesticide biochemistry and physiology.
2016 Sep; 132(?):13-20. doi:
10.1016/j.pestbp.2015.10.003. [PMID: 27521908] - Yueliang Zhang, Yaming Wang, Lihua Wang, Jing Yao, Huifang Guo, Jichao Fang. Knockdown of NADPH-cytochrome P450 reductase results in reduced resistance to buprofezin in the small brown planthopper, Laodelphax striatellus (fallén).
Pesticide biochemistry and physiology.
2016 Feb; 127(?):21-7. doi:
10.1016/j.pestbp.2015.08.006. [PMID: 26821654] - Xiaoli Chang, Yongda Yuan, Tianshu Zhang, Dongsheng Wang, Xingbin Du, Xiangwen Wu, Haixia Chen, Yaozhong Chen, Yuetong Jiao, Haiyuan Teng. The Toxicity and Detoxifying Mechanism of Cycloxaprid and Buprofezin in Controlling Sogatella furcifera (Homoptera: Delphacidae).
Journal of insect science (Online).
2015; 15(?):. doi:
10.1093/jisesa/iev077. [PMID: 26175461] - Siddharth Tiwari, Paul J Clayson, Emily H Kuhns, Lukasz L Stelinski. Effects of buprofezin and diflubenzuron on various developmental stages of Asian citrus psyllid, Diaphorina citri.
Pest management science.
2012 Oct; 68(10):1405-12. doi:
10.1002/ps.3323. [PMID: 22653617] - Wen-Wu Zhou, Xi-Wang Li, Yin-Hua Quan, Jiaan Cheng, Chuan-Xi Zhang, Geoff Gurr, Zeng-Rong Zhu. Identification and expression profiles of nine glutathione S-transferase genes from the important rice phloem sap-sucker and virus vector Laodelphax striatellus (Fallén) (Hemiptera: Delphacidae).
Pest management science.
2012 Sep; 68(9):1296-305. doi:
10.1002/ps.3297. [PMID: 22522784] - Jia Zhou, Lei Zhang, Yuwei Chang, Xin Lu, Zhen Zhu, Guowang Xu. Alteration of leaf metabolism in Bt-transgenic rice (Oryza sativa L.) and its wild type under insecticide stress.
Journal of proteome research.
2012 Aug; 11(8):4351-60. doi:
10.1021/pr300495x. [PMID: 22768924] - Arnaud Tonnelier, Sandra Coecke, José-Manuel Zaldívar. Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.
Archives of toxicology.
2012 Mar; 86(3):393-403. doi:
10.1007/s00204-011-0768-0. [PMID: 22089525] - Joshua S Wiley, Juan F García-Reyes, Jason D Harper, Nicholas A Charipar, Zheng Ouyang, R Graham Cooks. Screening of agrochemicals in foodstuffs using low-temperature plasma (LTP) ambient ionization mass spectrometry.
The Analyst.
2010 May; 135(5):971-9. doi:
10.1039/b919493b. [PMID: 20419245] - Yanhua Wang, Jin Chen, Yu Cheng Zhu, Chongyong Ma, Yue Huang, Jinliang Shen. Susceptibility to neonicotinoids and risk of resistance development in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae).
Pest management science.
2008 Dec; 64(12):1278-84. doi:
10.1002/ps.1629. [PMID: 18680157] - Yanhua Wang, Congfen Gao, Zhiping Xu, Yu Cheng Zhu, Jiushuang Zhang, Wenhong Li, Dejiang Dai, Youwei Lin, Weijun Zhou, Jinliang Shen. Buprofezin susceptibility survey, resistance selection and preliminary determination of the resistance mechanism in Nilaparvata lugens (Homoptera: Delphacidae).
Pest management science.
2008 Oct; 64(10):1050-6. doi:
10.1002/ps.1606. [PMID: 18506673] - P R Grundy. Utilizing the assassin bug, Pristhesancus plagipennis (Hemiptera: Reduviidae), as a biological control agent within an integrated pest management programme for Helicoverpa spp. (Lepidoptera: Noctuidae) and Creontiades spp. (Hemiptera: Miridae) in cotton.
Bulletin of entomological research.
2007 Jun; 97(3):281-90. doi:
10.1017/s0007485307004993. [PMID: 17524159] - Inamullah Khan, Sadrud Din, Said Khan Khalil, Muhammad Ather Rafi. Survey of predatory coccinellids (Coleoptera: Coccinellidae) in the Chitral District, Pakistan.
Journal of insect science (Online).
2007; 7(?):7. doi:
10.1673/031.007.0701. [PMID: 20334592] - I Ishaaya, V Khasdan, A Rami Horowitz. Effect of Zohar LQ-215, a biorational surfactant, on the sweetpotato whitefly Bemisia tabaci (biotype b).
Communications in agricultural and applied biological sciences.
2006; 71(2 Pt B):295-303. doi:
". [PMID: 17385496] - Ai-Hua Wang, Jin-Cai Wu, Yue-Shu Yu, Jing-Lan Liu, Jiang-Fei Yue, Mei-Yue Wang. Selective insecticide-induced stimulation on fecundity and biochemical changes in Tryporyza incertulas (Lepidoptera: Pyralidae).
Journal of economic entomology.
2005 Aug; 98(4):1144-9. doi:
10.1603/0022-0493-98.4.1144. [PMID: 16156564] - Steven E Naranjo, David H Akey. Conservation of natural enemies in cotton: comparative selectivity of acetamiprid in the management of Bemisia tabaci.
Pest management science.
2005 Jun; 61(6):555-66. doi:
10.1002/ps.1030. [PMID: 15712368] - A Garrido-Frenich, F J Arrebola, M J González-Rodríguez, J L Martínez Vidal, N Mora Díez. Rapid pesticide analysis, in post-harvest plants used as animal feed, by low-pressure gas chromatography-tandem mass spectrometry.
Analytical and bioanalytical chemistry.
2003 Nov; 377(6):1038-46. doi:
10.1007/s00216-003-2167-8. [PMID: 12955396] - Bozena Morzycka. Simple method for the determination of trace levels of pesticides in honeybees using matrix solid-phase dispersion and gas chromatography.
Journal of chromatography. A.
2002 Dec; 982(2):267-73. doi:
10.1016/s0021-9673(02)01505-4. [PMID: 12489883] - Kevin Gorman, Fiona Hewitt, Ian Denholm, Gregor J Devine. New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UK.
Pest management science.
2002 Feb; 58(2):123-30. doi:
10.1002/ps.427. [PMID: 11852636] - P Cabras, A Angioni, V L Garau, F M Pirisi, F Cabitza, M Pala. Acephate and buprofezin residues in olives and olive oil.
Food additives and contaminants.
2000 Oct; 17(10):855-8. doi:
10.1080/026520300420420. [PMID: 11103269]
