Albiflorin (BioDeep_00000000165)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


[(1R,3R,4R,6S,9S)-4-HYDROXY-6-METHYL-8-OXO-1-{[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY}-7-OXATRICYCLO[4.3.0.0(3),?]NONAN-9-YL]METHYL BENZOATE

化学式: C23H28O11 (480.1632)
中文名称: 芍药内酯苷, 白芍药苷, 白芍苷
谱图信息: 最多检出来源 Viridiplantae(plant) 37.77%

分子结构信息

SMILES: CC12CC(C3CC1(C3(C(=O)O2)COC(=O)C4=CC=CC=C4)OC5C(C(C(C(O5)CO)O)O)O)O
InChI: InChI=1S/C23H28O11/c1-21-8-13(25)12-7-23(21,33-19-17(28)16(27)15(26)14(9-24)32-19)22(12,20(30)34-21)10-31-18(29)11-5-3-2-4-6-11/h2-6,12-17,19,24-28H,7-10H2,1H3

描述信息

Albiflorin is a monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora. It has a role as a plant metabolite and a neuroprotective agent. It is a benzoate ester, a gamma-lactone, a beta-D-glucoside, a monoterpene glycoside, a secondary alcohol and a bridged compound.
Albiflorin is a natural product found in Paeonia lactiflora, Paeonia delavayi, and other organisms with data available.
A monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora.
Albiflorin, a major constituent contained in peony root, is a monoterpene glycoside with neuroprotective effects. Albiflorin also has anti-inflammatory, antioxidant and antinociceptive effects[1][2].
Albiflorin, a major constituent contained in peony root, is a monoterpene glycoside with neuroprotective effects. Albiflorin also has anti-inflammatory, antioxidant and antinociceptive effects[1][2].

同义名列表

9 个代谢物同义名

[4-Hydroxy-6-methyl-8-oxo-1-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7-oxatricyclo[4.3.0.03,9]nonan-9-yl]methyl benzoate; Albiflorin; [(1R,3R,4R,6S,9S)-4-HYDROXY-6-METHYL-8-OXO-1-{[(2S,3R,4S,5S,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY}-7-OXATRICYCLO[4.3.0.0(3),?]NONAN-9-YL]METHYL BENZOATE; [(1R,3R,4R,6S,9S)-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-8-oxo-7-oxatricyclo[4.3.0.0(3,9)]nonan-9-yl]methyl benzoate; 7-Oxatricyclo[4.3.0.03,9]nonan-8-one,9-[(benzoyloxy)methyl]-1-(b-D-glucopyranosyloxy)-4-hydroxy-6-methyl-,(1R,3R,4R,6S)-; Alibiflorin; [(1R,3R,4R,6S,9S)-4-hydroxy-6-methyl-8-oxo-1-[(2R,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7-oxatricyclo[4.3.0.03,9]nonan-9-yl]methyl benzoate; NCGC00169374-02_C23H28O11_7-Oxatricyclo[4.3.0.0~3,9~]nonan-8-one, 9-[(benzoyloxy)methyl]-1-(beta-D-glucopyranosyloxy)-4-hydroxy-6-methyl-, (1R,3R,4R,6S,9S)-; Albiflorin



数据库引用编号

49 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AKT1, BCL2, BDNF, CASP3, EGFR, NFE2L2, NLRP3, PIK3C3, PIK3CA, PTGS2, STAT3, VEGFA
Peripheral membrane protein 2 GORASP1, PTGS2
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 4 BCL2, EGFR, HMOX1, PTGS2
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 10 AKT1, BCL2, CASP3, EGFR, HMOX1, MPO, NFE2L2, NLRP3, STAT3, VEGFA
autophagosome 1 PIK3C3
cytosol 9 AKT1, BCL2, CASP3, HMOX1, NFE2L2, NLRP3, PIK3C3, PIK3CA, STAT3
dendrite 1 BDNF
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 1 NFE2L2
nucleoplasm 6 AKT1, CASP3, HMOX1, MPO, NFE2L2, STAT3
RNA polymerase II transcription regulator complex 2 NFE2L2, STAT3
Cell membrane 3 AKT1, EGFR, TNF
Cytoplasmic side 2 GORASP1, HMOX1
lamellipodium 2 AKT1, PIK3CA
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Golgi apparatus membrane 2 GORASP1, NLRP3
cell cortex 1 AKT1
cell junction 1 EGFR
cell surface 3 EGFR, TNF, VEGFA
glutamatergic synapse 4 AKT1, CASP3, EGFR, PIK3C3
Golgi apparatus 3 GORASP1, NFE2L2, VEGFA
Golgi membrane 4 EGFR, GORASP1, INS, NLRP3
neuronal cell body 2 CASP3, TNF
postsynapse 1 AKT1
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 2 NFE2L2, NLRP3
Lysosome 1 MPO
endosome 2 EGFR, PIK3C3
plasma membrane 6 AKT1, EGFR, NFE2L2, PIK3CA, STAT3, TNF
Membrane 8 AKT1, BCL2, BDNF, EGFR, HMOX1, NLRP3, PIK3C3, VEGFA
apical plasma membrane 1 EGFR
axon 2 BDNF, CCK
basolateral plasma membrane 1 EGFR
caveola 1 PTGS2
extracellular exosome 1 MPO
endoplasmic reticulum 5 BCL2, HMOX1, NLRP3, PTGS2, VEGFA
extracellular space 10 BDNF, CCK, EGFR, HMOX1, IL3, IL6, INS, MPO, TNF, VEGFA
perinuclear region of cytoplasm 4 BDNF, EGFR, HMOX1, PIK3CA
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
mitochondrion 2 BCL2, NLRP3
protein-containing complex 4 AKT1, BCL2, EGFR, PTGS2
intracellular membrane-bounded organelle 1 MPO
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 EGFR
Secreted 7 BDNF, CCK, IL3, IL6, INS, NLRP3, VEGFA
extracellular region 9 BDNF, CCK, IL3, IL6, INS, MPO, NLRP3, TNF, VEGFA
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 2 BCL2, HMOX1
transcription regulator complex 1 STAT3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 2 BCL2, EGFR
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 VEGFA
microtubule cytoskeleton 1 AKT1
midbody 1 PIK3C3
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Membrane raft 2 EGFR, TNF
pore complex 1 BCL2
focal adhesion 1 EGFR
spindle 1 AKT1
GABA-ergic synapse 1 PIK3C3
cis-Golgi network 1 GORASP1
extracellular matrix 1 VEGFA
Peroxisome 1 PIK3C3
intracellular vesicle 1 EGFR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
secretory granule 2 MPO, VEGFA
axoneme 1 PIK3C3
Cytoplasm, cytoskeleton, microtubule organizing center 1 NLRP3
Inflammasome 1 NLRP3
interphase microtubule organizing center 1 NLRP3
NLRP3 inflammasome complex 1 NLRP3
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 PIK3C3
receptor complex 1 EGFR
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 2 NFE2L2, STAT3
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
Endomembrane system 1 NLRP3
endosome lumen 1 INS
microtubule organizing center 1 NLRP3
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
myelin sheath 1 BCL2
basal plasma membrane 1 EGFR
azurophil granule 1 MPO
synaptic membrane 1 EGFR
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 BDNF, IL6, INS, PTGS2
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
presynaptic endosome 1 PIK3C3
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
Single-pass type IV membrane protein 1 HMOX1
clathrin-coated endocytic vesicle membrane 1 EGFR
phagocytic vesicle lumen 1 MPO
protein-DNA complex 1 NFE2L2
death-inducing signaling complex 1 CASP3
postsynaptic endosome 1 PIK3C3
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
Autolysosome 1 PIK3C3
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Cuicui Xu, Xinke Wang, Jinlong Han, Zhengwei Gu, Qingmei Guo. LMD and LC-MS-based chemical constituents and pharmacological effects assessment for two different processing methods of the root of Paeonia lactiflora Pall. Journal of pharmaceutical and biomedical analysis. 2024 Aug; 245(?):116184. doi: 10.1016/j.jpba.2024.116184. [PMID: 38692214]
  • Hui Xue, Jing Jiang, Yue Zhang, Xue-Tong Meng, Ao Xue, Yue Qiao, Xia Lei, Ji-Hui Zhao, Ning Zhang. [Mechanism of albiflorin in improvement of Alzheimer's disease based on network pharmacology and in vitro experiments]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Sep; 48(17):4738-4746. doi: 10.19540/j.cnki.cjcmm.20230510.701. [PMID: 37802813]
  • Pengfei Fang, Yi Wang, Fengqi Sun, Haisheng Lin, Xindong Zhang. Effects of albiflorin on oxidative stress and inflammatory responses in rats with acute spinal cord injury. Immunity, inflammation and disease. 2023 09; 11(9):e1015. doi: 10.1002/iid3.1015. [PMID: 37773716]
  • Zhihao Liu, Qixiang Shang, Haimeng Li, Daozheng Fang, Zhuohuan Li, Yuqi Huang, Mimi Zhang, Kam Ming Ko, Jihang Chen. Exploring the possible mechanism(s) underlying the nephroprotective effect of Zhenwu Decoction in diabetic kidney disease: An integrated analysis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jul; 119(?):154988. doi: 10.1016/j.phymed.2023.154988. [PMID: 37523837]
  • Yudan Mei, Xiaoyu Tong, Yumei Hu, Wenjun Liu, Jiajia Wang, Kaihong Lv, Xu Li, Liang Cao, Zhenzhong Wang, Wei Xiao, Xia Gao. Comparative pharmacokinetics of six bioactive components of Shen-Wu-Yi-Shen tablets in normal and chronic renal failure rats based on UPLC-TSQ-MS/MS. Journal of ethnopharmacology. 2023 Jun; 317(?):116818. doi: 10.1016/j.jep.2023.116818. [PMID: 37348793]
  • Xia'nan Sang, Xuedong Wan, Han Zhang, Jialiang Ying, Lu Wang, Qiao Yang, Qiyuan Shan, Min Hao, Minjing Qin, Qitong Zheng, Quan Chen, Xin Han, Gang Cao. The most bioactive fraction of stir-fried Radix Paeoniae Alba regulating IL-6/STAT3 signaling pathway in allergic asthma mouse. Journal of ethnopharmacology. 2023 Jan; 301(?):115821. doi: 10.1016/j.jep.2022.115821. [PMID: 36220510]
  • Rui-Xin Li, Cai-Lian Fan, Wan-Yi Xu, Wen Wei, Xiao-Xing Wang, Zi-Ting Li, Peng-Cheng Zhao, Zhi-Jian Su, Xi-Yang Tang, Zhi-Hong Yao, Yi Dai. Simultaneous determination of multiple constituents of Qi-Lin pill by UPLC-MS/MS: Applications to pharmacokinetics and testicular tissue distribution in rats. Journal of pharmaceutical and biomedical analysis. 2023 Jan; 223(?):115157. doi: 10.1016/j.jpba.2022.115157. [PMID: 36379101]
  • Rong Yang, Yang Yang. Albiflorin attenuates high glucose-induced endothelial apoptosis via suppressing PARP1/NF-κB signaling pathway. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2023 Jan; 72(1):159-169. doi: 10.1007/s00011-022-01666-z. [PMID: 36357814]
  • Xiao Li, Ruihong Hou, Xuemei Qin, Yanfei Wu, Xingkang Wu, Junsheng Tian, Xiaoxia Gao, Guanhua Du, Yuzhi Zhou. Synergistic neuroprotective effect of saikosaponin A and albiflorin on corticosterone-induced apoptosis in PC12 cells via regulation of metabolic disorders and neuroinflammation. Molecular biology reports. 2022 Sep; 49(9):8801-8813. doi: 10.1007/s11033-022-07730-5. [PMID: 36002654]
  • Yeling Liu, Yilai Sun, Xue Bai, Lingxing Li, Guihua Zhu. Albiflorin Alleviates Ox-LDL-Induced Human Umbilical Vein Endothelial Cell Injury through IRAK1/TAK1 Pathway. BioMed research international. 2022; 2022(?):6584645. doi: 10.1155/2022/6584645. [PMID: 35601145]
  • Dong Xu, Tao Qiao, Yue Wang, Qiang-Song Wang, Yuan-Lu Cui. Alginate nanogels-based thermosensitive hydrogel to improve antidepressant-like effects of albiflorin via intranasal delivery. Drug delivery. 2021 Dec; 28(1):2137-2149. doi: 10.1080/10717544.2021.1986604. [PMID: 34617853]
  • Qiang-Song Wang, Kuo Yan, Kuang-Dai Li, Li-Na Gao, Xu Wang, Haibo Liu, Zuoguang Zhang, Kefeng Li, Yuan-Lu Cui. Targeting hippocampal phospholipid and tryptophan metabolism for antidepressant-like effects of albiflorin. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Nov; 92(?):153735. doi: 10.1016/j.phymed.2021.153735. [PMID: 34601221]
  • Xiaojun Ma, Min Song, Yushan Yan, Gaofei Ren, Jingwen Hou, Guijun Qin, Wang Wang, Zhizhen Li. Albiflorin alleviates cognitive dysfunction in STZ-induced rats. Aging. 2021 07; 13(14):18287-18297. doi: 10.18632/aging.203274. [PMID: 34319254]
  • Tingting Liu, Min Zhao, Yumeng Zhang, Zhaozhao Qiu, Yixin Zhang, Chunjie Zhao, Miao Wang. Pharmacokinetic-pharmacodynamic modeling analysis and anti-inflammatory effect of Wangbi capsule in the treatment of adjuvant-induced arthritis. Biomedical chromatography : BMC. 2021 Jul; 35(7):e5101. doi: 10.1002/bmc.5101. [PMID: 33625739]
  • Pei Liu, Jianjun Chen, Shuai Ma, Jianjun Zhang, Jianyu Zhou. Albiflorin Attenuates Mood Disorders Under Neuropathic Pain State by Suppressing the Hippocampal NLRP3 Inflammasome Activation During Chronic Constriction Injury. The international journal of neuropsychopharmacology. 2021 01; 24(1):64-76. doi: 10.1093/ijnp/pyaa076. [PMID: 33000169]
  • Qilin Fan, Xiaojing Guan, Yuanlong Hou, Yali Liu, Wei Wei, Xiaoying Cai, Youying Zhang, Guangji Wang, Xiao Zheng, Haiping Hao. Paeoniflorin modulates gut microbial production of indole-3-lactate and epithelial autophagy to alleviate colitis in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Dec; 79(?):153345. doi: 10.1016/j.phymed.2020.153345. [PMID: 33002829]
  • Ying-Li Zhu, Lin-Yuan Wang, Dan-Ping Zhao, Cheng-Long Wang, Rui Zhang, Wen-Ting Fei, Jing-Xia Wang, Jian-Jun Zhang. Antidepressant-like effects of albiflorin involved the NO signaling pathway in rats model of chronic restraint stress. Chinese journal of natural medicines. 2020 Nov; 18(11):872-880. doi: 10.1016/s1875-5364(20)60030-9. [PMID: 33308610]
  • Heyun Zhu, Jiao Guan, Hui Zhang, Sheng Chang, Liming Wang, Jianyi Shi, Bo Feng, Jingkai Gu. Simultaneous determination of ferulic acid, paeoniflorin, and albiflorin in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry: Application to a pharmacokinetic study of Danggui-Shaoyao-San. Journal of separation science. 2020 Jun; 43(11):2053-2060. doi: 10.1002/jssc.201900846. [PMID: 32112520]
  • Jun-Jin Liu, Yao Cheng, Yun-Yun Shao, Zhuang-Peng Chang, Yi-Ting Guo, Xiao-Juan Feng, Ding Xu, Jing-Ping Zhang, Yan Song, Rui-Gang Hou. Comparative pharmacokinetics and metabolites study of seven major bioactive components of Shaoyao-Gancao decoction in normal and polycystic ovary syndrome rats by ultra high pressure liquid chromatography with tandem mass spectrometry. Journal of separation science. 2019 Aug; 42(15):2534-2549. doi: 10.1002/jssc.201900002. [PMID: 31144455]
  • Jiao Guan, Liming Wang, Jia Jin, Sheng Chang, Xiao Xiao, Bo Feng, Heyun Zhu. Simultaneous determination of calycosin-7-O-β-D-glucoside, cinnamic acid, paeoniflorin and albiflorin in rat plasma by UHPLC-MS/MS and its application to a pharmacokinetic study of Huangqi Guizhi Wuwu Decoction. Journal of pharmaceutical and biomedical analysis. 2019 Jun; 170(?):1-7. doi: 10.1016/j.jpba.2019.03.022. [PMID: 30897430]
  • Jiyou Sun, Xiaojuan Li, Kai Jiao, Zhiwei Zhai, Dajun Sun. Albiflorin inhibits the formation of THP-1-derived foam cells through the LOX-1/NF-κB pathway. Minerva medica. 2019 Apr; 110(2):107-114. doi: 10.23736/s0026-4806.18.05711-7. [PMID: 30371044]
  • Yezhe Cheng, Yanjie Chu, Xitong Su, Kexia Zhang, Yu Zhang, Zhenzhong Wang, Wei Xiao, Longshan Zhao, Xiaohui Chen. Pharmacokinetic-pharmacodynamic modeling to study the anti-dysmenorrhea effect of Guizhi Fuling capsule on primary dysmenorrhea rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2018 Sep; 48(?):141-151. doi: 10.1016/j.phymed.2018.04.041. [PMID: 30195872]
  • Xinwen Lv, Yongbing Zhang, Hujin Zhang. Neuroprotective effect of Trichosanthes kirilowii cassia twig on cerebral ischemia-reperfusion injury in rats. Pakistan journal of pharmaceutical sciences. 2018 Jul; 31(4(Special)):1643-1647. doi: . [PMID: 30203753]
  • Xiujun Wu, Yang You, Gonglin Qu, Ran Ma, Mingxue Zhang. Simultaneous determination of ginsenoside Rb1, ginsenoside Rg1, paeoniflorin, albiflorin and oxypaeoniflorin in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study of wen-Yang-Huo-Xue soft capsule. Biomedical chromatography : BMC. 2017 Dec; 31(12):. doi: 10.1002/bmc.4019. [PMID: 28557007]
  • Zhigang Wang, Shuhan Tang, Masao Hattori, Hailong Zhang, Xiuhong Wu. Simultaneous determination of paeonilactone A and paeonilactone B in rat plasma after oral administration of albiflorin by UPLC/TOF/MS following picolinoyl derivatization. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2017 Sep; 1061-1062(?):327-333. doi: 10.1016/j.jchromb.2017.07.047. [PMID: 28783562]
  • Hao Zhan, Jing Fang, Liying Tang, Hongjun Yang, Hua Li, Zhuju Wang, Bin Yang, Hongwei Wu, Meihong Fu. Application of near-infrared spectroscopy for the rapid quality assessment of Radix Paeoniae Rubra. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2017 Aug; 183(?):75-83. doi: 10.1016/j.saa.2017.04.034. [PMID: 28437688]
  • Mi-Young Jeong, Jinbong Park, Dong-Hyun Youn, Yunu Jung, JongWook Kang, Seona Lim, Min-Woo Kang, Hye-Lin Kim, Hong-Seob So, Raekil Park, Seung-Heon Hong, Jae-Young Um. Albiflorin ameliorates obesity by inducing thermogenic genes via AMPK and PI3K/AKT in vivo and in vitro. Metabolism: clinical and experimental. 2017 08; 73(?):85-99. doi: 10.1016/j.metabol.2017.05.009. [PMID: 28732574]
  • Pingyao Xie, Lili Cui, Yuan Shan, Wen-Yi Kang. Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra. BioMed research international. 2017; 2017(?):9475074. doi: 10.1155/2017/9475074. [PMID: 28299338]
  • Yan-Hong Shi, Shu Zhu, Yue-Wei Ge, Kazufumi Toume, Zhengtao Wang, Javzan Batkhuu, Katsuko Komatsu. Characterization and quantification of monoterpenoids in different types of peony root and the related Paeonia species by liquid chromatography coupled with ion trap and time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2016 Sep; 129(?):581-592. doi: 10.1016/j.jpba.2016.07.031. [PMID: 27521818]
  • Yizhi Zhang, Dejun Sun, Qingjin Meng, Wanxu Guo, Qiuhui Chen, Ying Zhang. Calcium channels contribute to albiflorin-mediated antinociceptive effects in mouse model. Neuroscience letters. 2016 08; 628(?):105-9. doi: 10.1016/j.neulet.2016.03.054. [PMID: 27038516]
  • Ying-Li Zhu, Lin-Yuan Wang, Jing-Xia Wang, Chun Wang, Cheng-Long Wang, Dan-Ping Zhao, Zi-Chen Wang, Jian-Jun Zhang. Protective effects of paeoniflorin and albiflorin on chemotherapy-induced myelosuppression in mice. Chinese journal of natural medicines. 2016 Aug; 14(8):599-606. doi: 10.1016/s1875-5364(16)30070-x. [PMID: 27608949]
  • Weizhe Xu, Yan Zhao, Yi Qin, Beikang Ge, Wenwen Gong, Yingting Wu, Xiaorong Li, Yuming Zhao, Pingxiang Xu, Ming Xue. Enhancement of Exposure and Reduction of Elimination for Paeoniflorin or Albiflorin via Co-Administration with Total Peony Glucosides and Hypoxic Pharmacokinetics Comparison. Molecules (Basel, Switzerland). 2016 Jul; 21(7):. doi: 10.3390/molecules21070874. [PMID: 27376264]
  • Fei Fei, Hailing Yang, Ying Peng, Pei Wang, Shuyao Wang, Yuqing Zhao, Jingqiu Huang, Xiaoyi Yu, Siqi Feng, Runbin Sun, Na Yang, Hongbo Wang, Jiye Aa, Guangji Wang. Sensitive analysis and pharmacokinetic study of the isomers paeoniflorin and albiflorin after oral administration of Total Glucosides Of White Paeony Capsule in rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2016 Jun; 1022(?):30-37. doi: 10.1016/j.jchromb.2016.04.005. [PMID: 27070118]
  • Yunlai Wang, Guoqiang Li, Yu Zhou, Dengke Yin, Chunlei Tao, Lan Han, Xiaoli Yue, Yongfu Pan, Yao Yao, Daiyin Peng, Fan Xu. The difference between blood-associated and water-associated herbs of Danggui-Shaoyao San in theory of TCM, based on serum pharmacochemistry. Biomedical chromatography : BMC. 2016 Apr; 30(4):579-87. doi: 10.1002/bmc.3586. [PMID: 26270156]
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