Edetic Acid (BioDeep_00000001468)

human metabolite blood metabolite Chemicals and Drugs

代谢物信息卡片

2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid

化学式: C10H16N2O8 (292.0906616)
中文名称: 乙二胺四乙酸
谱图信息: 最多检出来源 Macaca mulatta(otcml) 0.11%

分子结构信息

SMILES: C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O
InChI: InChI=1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

描述信息

Edetic Acid is only found in individuals that have used or taken this drug. It is a chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive. [PubChem]The pharmacologic effects of edetate calcium disodium are due to the formation of chelates with divalent and trivalent metals. A stable chelate will form with any metal that has the ability to displace calcium from the molecule, a feature shared by lead, zinc, cadmium, manganese, iron and mercury. The amounts of manganese and iron metabolized are not significant. Copper is not mobilized and mercury is unavailable for chelation because it is too tightly bound to body ligands or it is stored in inaccessible body compartments. The excretion of calcium by the body is not increased following intravenous administration of edetate calcium disodium, but the excretion of zinc is considerably increased.
D064449 - Sequestering Agents > D002614 - Chelating Agents > D065096 - Calcium Chelating Agents
C78275 - Agent Affecting Blood or Body Fluid > C263 - Anticoagulant Agent
D000074385 - Food Ingredients > D005503 - Food Additives
D006401 - Hematologic Agents > D000925 - Anticoagulants

同义名列表

82 个代谢物同义名

2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid; {[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetIC ACID; {[-(bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetate; 2,2,2,2-(ethane-1,2-diyldinitrilo)tetraacetic acid; N,N-1,2-ethane diylbis-(N-(carboxymethyl)glycine); N,N-1,2-ethanediylbis(N-(carboxymethyl)glycine); 2,2,2,2-(ethane-1,2-diyldinitrilo)tetraacetate; (Ethylenedinitrilo)tetraacetic acid, ion(4-); Edetic acid, disodium, monopotassium salt; Dinitrilotetraacetate, disodium ethylene; Ethylene dinitrilotetraacetate, disodium; (Ethylenedinitrilo)tetraacetate, ion(4-); Disodium ethylene dinitrilotetraacetate; Edetic acid, disodium, magnesium salt; Edetic acid, disodium salt, dihydrate; Acid, ethylenedinitrilotetraacetic; Ethylenedinitrilotetraacetic acid; Acide ethylenediaminetetracetique; Edetic acid, calcium, sodium salt; Acid, ethylenediaminetetraacetic; Ethylenediaminetetraacetic acid; Edetic acid, monopotassium salt; Dinitrilotetraacetate, ethylene; Ethylene dinitrilotetraacetate; Edetic acid, dipotassium salt; Edetic acid, monosodium salt; Edetic acid, magnesium salt; Ethylenediaminetetraacetate; Edetic acid, potassium salt; Disodium versenate, calcium; Versenate, calcium disodium; Edetic acid, disodium salt; Calcitetracemate, disodium; Edetic acid, chromium salt; Calcium disodium versenate; Disodium calcitetracemate; Edetic acid, calcium salt; Edetate, calcium disodium; Edetate disodium calcium; Edetate calcium disodium; EDTA, magnesium disodium; Calcium disodium edetate; Edetic acid, sodium salt; Magnesium disodium edta; Tetacine, calcium; EDTA, distannous; Calcium tetacine; Edetate calcium; Distannous edta; EDTA, potassium; Acidum edeticum; Acide edetique; EDTA, disodium; EDTA, stannous; EDTA, dicobalt; Potassium edta; EDTA, chromium; Chromium edta; Stannous edta; Disodium edta; EDTA, gallium; EDTA, ion(4-); Dicobalt edta; Acido edetico; EDTA, copper; Versene acid; Acid, edetic; Gallium edta; Edetic Acid; Copper edta; Tetracemate; Chelaton 3; Versenate; Edathamil; Edetates; Versene; Edetate; H4EDta; Coprin; CaEDTA; EDTA; EDT

数据库引用编号

22 个数据库交叉引用编号

ChEBI: CHEBI:42191
ChEBI: CHEBI:4735
KEGG: C00284
KEGGdrug: D00052
PubChem: 6049
HMDB: HMDB0015109
Metlin: METLIN4007
DrugBank: DB00974
ChEMBL: CHEMBL858
Wikipedia: Edetate
MeSH: Edetic Acid
chemspider: 5826
CAS: 470462-56-7
CAS: 6381-92-6
CAS: 688-55-1
CAS: 139-33-3
CAS: 60-00-4
PMhub: MS000000585
PubChem: 3579
PDB-CCD: EDT
NIKKAJI: J4.406G
RefMet: Edetic acid

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Abolghassem Emamverdian, Ahlam Khalofah, Necla Pehlivan, Yang Li, Moxian Chen, Guohua Liu. Iron nanoparticles in combination with other conventional Fe sources remediate mercury toxicity-affected plants and soils by nutrient accumulation in bamboo species. Ecotoxicology and environmental safety. 2024 Jun; 278(?):116431. doi: 10.1016/j.ecoenv.2024.116431. [PMID: 38718730]
Marina Rafiq, Muhammad Shahid, Irshad Bibi, Sana Khalid, Tasveer Zahra Tariq, Abdullah A Al-Kahtani, Zeid A ALOthman, Behzad Murtaza, Nabeel Khan Niazi. Role of organic and inorganic amendments on physiological attributes of germinating pea seedlings under arsenic stress. International journal of phytoremediation. 2024 Jun; 26(8):1243-1252. doi: 10.1080/15226514.2024.2305684. [PMID: 38265045]
Rachel Irankunda, Mads Bjørlie, Betül Yesiltas, Laurence Muhr, Laetitia Canabady-Rochelle, Charlotte Jacobsen. Evaluation of primary and secondary oxidation products in fish oil-in-water emulsions: Effect of metal-complexing peptides and protein hydrolysates. Food chemistry. 2024 May; 439(?):138042. doi: 10.1016/j.foodchem.2023.138042. [PMID: 38100881]
Juan Francisco Morales Arteaga, Dominik Vodnik, Damijana Kastelec, Mojca Zupanc, Matevž Dular, Jernej Ortar, Marija Đurić, Anela Kaurin, Rok Mihelic, Domen Lestan. Removal of toxic metals from sewage sludge by EDTA and hydrodynamic cavitation and use of the sludge as fertilizer. The Science of the total environment. 2024 May; 923(?):171444. doi: 10.1016/j.scitotenv.2024.171444. [PMID: 38438036]
Ting Liu, Xiaomin Yuan, Kun Luo, Can Xie, Liyi Zhou. Molecular engineering of a new method for effective removal of cadmium from water. Water research. 2024 Apr; 253(?):121326. doi: 10.1016/j.watres.2024.121326. [PMID: 38377928]
Izabela Jośko, Magdalena Kusiak, Magdalena Sozoniuk, Mikołaj Feculak, Kevin C-W Wu, Melissa Fitzgerald, Mohamed Salem Alyafei, Mohamed Salah Sheteiwy. Analysis of multiple biomarkers revealed the size matters of Cu particles for barley response under foliar exposure. The Science of the total environment. 2024 Mar; 918(?):170673. doi: 10.1016/j.scitotenv.2024.170673. [PMID: 38316301]
Abdulrahman Alhashimi, Ayman Abdelkareem, Mohamed A Amin, Abdelatti I Nowwar, Amr Fouda, Mohamed A Ismail, Abeer E Mustafa, Maha Alharbi, Amr Elkelish, Abdelrahman M Sayed, Hanan A Said. Eco-friendly approach to decrease the harmful effects of untreated wastewater on growth, yield, biochemical constituents, and heavy metal contents of carrot (Daucus carota L.). Environmental science and pollution research international. 2024 Jan; ?(?):. doi: 10.1007/s11356-024-31869-2. [PMID: 38273079]
Ping Huang, Shoucheng Huang, Yuhan Ma, Subhan Danish, Misbah Hareem, Asad Syed, Abdallah M Elgorban, Rajalakshmanan Eswaramoorthy, Ling Shing Wong. Alleviation of salinity stress by EDTA chelated-biochar and arbuscular mycorrhizal fungi on maize via modulation of antioxidants activity and biochemical attributes. BMC plant biology. 2024 Jan; 24(1):63. doi: 10.1186/s12870-024-04753-x. [PMID: 38262953]
Salwinder Singh Dhaliwal, Vivek Sharma, Arvind Kumar Shukla, Parminder Kaur Taneja, Lovedeep Kaur, Vibha Verma, Manmeet Kaur, Janpriya Kaur. Exploration of Cd transformations in Cd spiked and EDTA-chelated soil for phytoextraction by Brassica species. Environmental geochemistry and health. 2023 Dec; 45(12):8897-8909. doi: 10.1007/s10653-022-01260-6. [PMID: 35484423]
Elisa Varona, Pedro J García-Moreno, Simon Gregersen Echers, Tobias H Olsen, Paolo Marcatili, Francesc Guardiola, Michael T Overgaard, Egon B Hansen, Charlotte Jacobsen, Betül Yesiltas. Antioxidant peptides from alternative sources reduce lipid oxidation in 5\% fish oil-in-water emulsions (pH 4) and fish oil-enriched mayonnaise. Food chemistry. 2023 Nov; 426(?):136498. doi: 10.1016/j.foodchem.2023.136498. [PMID: 37295051]
Vasiliy Brusko, Bulat Garifullin, Gulnaz Geniyatullina, Polina Kuryntseva, Gulnaz Galieva, Polina Galitskaya, Svetlana Selivanovskaya, Ayrat M Dimiev. Novel Biodegradable Chelating Agents for Micronutrient Fertilization. Journal of agricultural and food chemistry. 2023 Oct; 71(41):14979-14988. doi: 10.1021/acs.jafc.3c03500. [PMID: 37791964]
Zzu-Ying Huang, Cho-Yin Wu, Zeng-Yei Hseu. Rare earth elements in tea garden soils and their bioavailability to tea buds in Taiwan. The Science of the total environment. 2023 Oct; 893(?):164895. doi: 10.1016/j.scitotenv.2023.164895. [PMID: 37321509]
Dino Davosir, Ivana Šola. Membrane permeabilizers enhance biofortification of Brassica microgreens by interspecific transfer of metabolites from tea (Camellia sinensis). Food chemistry. 2023 Sep; 420(?):136186. doi: 10.1016/j.foodchem.2023.136186. [PMID: 37087866]
Gul Naaz, Naushad Alam, Amit Kumar. Impact of ethylene diamine tetraacetic acid on physiochemical parameters and yield attribute in two varieties of Brassica juncea under lead stress. Environmental science and pollution research international. 2023 Aug; ?(?):. doi: 10.1007/s11356-023-29204-2. [PMID: 37599348]
Mohammed F Alkadhem, Lucie M F Wagenmakers-Huizenga, Marjan Wouthuyzen-Bakker, Anneke C Muller Kobold. (Pre)analytical considerations concerning the analysis of synovial calprotectin. Clinical chemistry and laboratory medicine. 2023 Aug; ?(?):. doi: 10.1515/cclm-2023-0484. [PMID: 37529863]
Jolien De Paepe, David Garcia Gragera, Carolina Arnau Jimenez, Korneel Rabaey, Siegfried E Vlaeminck, Francesc Gòdia. Continuous cultivation of microalgae yields high nutrient recovery from nitrified urine with limited supplementation. Journal of environmental management. 2023 Aug; 345(?):118500. doi: 10.1016/j.jenvman.2023.118500. [PMID: 37542810]
Lijun Li, Bao Jiang, Kun Li, Jumei Li, Yibing Ma. Accurate derivation and modelling of criteria of soil extractable and total cadmium for safe wheat production. Ecotoxicology and environmental safety. 2023 Aug; 261(?):115092. doi: 10.1016/j.ecoenv.2023.115092. [PMID: 37285673]
Ya-Shiou Chang. Effects of stepwise chilling with calcium incubation on proteolysis and tenderization in postmortem goose muscle. Poultry science. 2023 Aug; 102(8):102811. doi: 10.1016/j.psj.2023.102811. [PMID: 37300909]
Katarina Vazdar, Carmelo Tempra, Agnieszka Olżyńska, Denys Biriukov, Lukasz Cwiklik, Mario Vazdar. Stealthy Player in Lipid Experiments? EDTA Binding to Phosphatidylcholine Membranes Probed by Simulations and Monolayer Experiments. The journal of physical chemistry. B. 2023 06; 127(24):5462-5469. doi: 10.1021/acs.jpcb.3c03207. [PMID: 37307026]
Muhammad Zia-Ur-Rehman, Manar Fawzi Bani Mfarrej, Muhammad Usman, Sidra Anayatullah, Muhammad Rizwan, Hesham F Alharby, Isam M Abu Zeid, Nadiyah M Alabdallah, Shafaqat Ali. Effect of iron nanoparticles and conventional sources of Fe on growth, physiology and nutrient accumulation in wheat plants grown on normal and salt-affected soils. Journal of hazardous materials. 2023 Jun; 458(?):131861. doi: 10.1016/j.jhazmat.2023.131861. [PMID: 37336110]
Diego Medina Caro, Lucas Horstmann, Lars Ganzert, Romulo Oses, Thomas Friedl, Dirk Wagner. An improved method for intracellular DNA (iDNA) recovery from terrestrial environments. MicrobiologyOpen. 2023 06; 12(3):e1369. doi: 10.1002/mbo3.1369. [PMID: 37379428]
Qingqing Wang, Miriam Hoene, Chunxiu Hu, Louise Fritsche, Robert Ahrends, Gerhard Liebisch, Kim Ekroos, Andreas Fritsche, Andreas L Birkenfeld, Xinyu Liu, Xinjie Zhao, Qi Li, Benzhe Su, Andreas Peter, Guowang Xu, Rainer Lehmann. Ex vivo instability of lipids in whole blood: preanalytical recommendations for clinical lipidomics studies. Journal of lipid research. 2023 06; 64(6):100378. doi: 10.1016/j.jlr.2023.100378. [PMID: 37087100]
Manhattan Lebrun, Jiřina Száková, Ondřej Drábek, Václav Tejnecký, Rupert Lloyd Hough, Luke Beesley, Hailong Wang, Lukáš Trakal. EDTA as a legacy soil chelatant: a comparative study to a more environmentally sensitive alternative for metal removal by Pistia stratiotes L. Environmental science and pollution research international. 2023 May; ?(?):. doi: 10.1007/s11356-023-27537-6. [PMID: 37202639]
Yazmín Stefani Perea-Vélez, Rogelio Carrillo-González, Ma Del Carmen A González-Chávez, Jaco Vangronsveld, Iván Ortiz Monasterio, Daniel Tapia Maruri. Citrate-coated cobalt ferrite nanoparticles for the nano-enabled biofortification of wheat. Food & function. 2023 May; 14(9):4017-4035. doi: 10.1039/d2fo03835h. [PMID: 37067010]
Changxiao Chen, Qi Meng, Zhendong Liu, Sainan Liu, Weifang Tong, Baichao An, Binbin Ding, Ping'an Ma, Jun Lin. Iron oxide-EDTA nanoparticles for chelation-enhanced chemodynamic therapy and ion interference therapy. Biomaterials science. 2023 May; ?(?):. doi: 10.1039/d3bm00371j. [PMID: 37159049]
Tiffany Ho, Keegan Guidolin, Ali Makky, Michael Valic, Lili Ding, Jiachuan Bu, Mark Zheng, Miffy H Y Cheng, Jeremy Yau, Juan Chen, Gang Zheng. Novel Strategy to Drive the Intracellular Uptake of Lipid Nanoparticles for Photodynamic Therapy. Angewandte Chemie (International ed. in English). 2023 04; 62(16):e202218218. doi: 10.1002/anie.202218218. [PMID: 36811315]
A Tahir, F Ur-Rehman Qazi, Z Choudhry, U Musheer, M Amin, S Malik, A A AlMokhatieb, K Almadi, M F Alkahtany, M A Ahmed, K Ali, F Vohra, T Abduljabbar. Influence of Sapindus mukorossi extract in comparison to 17\% EDTA as final root canal irrigant on the sealer penetration and microleakage of dentinal tubules. European review for medical and pharmacological sciences. 2023 04; 27(7):2724-2732. doi: 10.26355/eurrev_202304_31899. [PMID: 37070870]
Guiyin Wang, Yan Yang, Xiaoxun Xu, Shirong Zhang, Zhanbiao Yang, Zhang Cheng, Junren Xian, Ting Li, Yulin Pu, Wei Zhou, Gang Xiang, Zhien Pu. Rape Straw Supported FeS Nanoparticles with Encapsulated Structure as Peroxymonosulfate and Hydrogen Peroxide Activators for Enhanced Oxytetracycline Degradation. Molecules (Basel, Switzerland). 2023 Mar; 28(6):. doi: 10.3390/molecules28062771. [PMID: 36985744]
Danting Yang, Haojie Shi, Ke Zhang, Xunyue Liu, Liang Ma. The antifungal potential of the chelating agent EDTA against postharvest plant pathogen Botrytis cinerea. International journal of food microbiology. 2023 Mar; 388(?):110089. doi: 10.1016/j.ijfoodmicro.2023.110089. [PMID: 36682298]
Jin Wang, Kai-Xiao Ye, Yan Tian, Ke Liu, Liu-Ling Liang, Qing-Qian Li, Ning Huang, Xin-Ting Wang. [Simultaneous determination of 22 antibiotics in environmental water samples by solid phase extraction-high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2023 Mar; 41(3):241-249. doi: 10.3724/sp.j.1123.2022.06004. [PMID: 36861207]
Steven Kopcho, Marina McDew-White, Wasifa Naushad, Mahesh Mohan, Chioma M Okeoma. SIV Infection Regulates Compartmentalization of Circulating Blood Plasma miRNAs within Extracellular Vesicles (EVs) and Extracellular Condensates (ECs) and Decreases EV-Associated miRNA-128. Viruses. 2023 Feb; 15(3):. doi: 10.3390/v15030622. [PMID: 36992331]
Muhammad Zia-Ur-Rehman, Arisha Mubsher, Muhammad Rizwan, Muhammad Usman, Muhammad Jafir, Muhammad Umair, Hesham F Alharby, Atif A Bamagoos, Rahma Alshamrani, Shafaqat Ali. Effect of farmyard manure, elemental sulphur and EDTA on growth and phytoextraction of cadmium by spider plants (Chlorophytum comosum L.) under Cd stress. Chemosphere. 2023 Feb; 313(?):137385. doi: 10.1016/j.chemosphere.2022.137385. [PMID: 36436583]
Sofia M Borges, Cláudia Santos, M Fátima Macedo. Monocyte antigen-presenting capacity to iNKT cells is influenced by the blood collection conditions. Journal of immunological methods. 2023 02; 513(?):113426. doi: 10.1016/j.jim.2023.113426. [PMID: 36638882]
Xiao-Die Cui, Jun-Kai Zhang, Ya-Wei Sun, Feng-Bin Yan, Jin-Feng Zhao, Dan-Dan He, Yu-Shan Pan, Li Yuan, Ya-Jun Zhai, Gong-Zheng Hu. Synergistic antibacterial activity of baicalin and EDTA in combination with colistin against colistin-resistant Salmonella. Poultry science. 2023 Feb; 102(2):102346. doi: 10.1016/j.psj.2022.102346. [PMID: 36493546]
Chunjian Zhao, Xin Li, Chunying Li, Shen Li, Yao Tian, TTingting Wang, Yujie Fu. Ingenious application of ethylenediaminetetraacetic acid disodium to improve the extraction yield of psoralen in fig (Ficus carica L.) leaves. Natural product research. 2023 Feb; 37(3):508-513. doi: 10.1080/14786419.2021.1980792. [PMID: 34546825]
Susheel Kumar Sharma, Neeta Pathaw, Baby Wangkhem, Kabrabam Suraj Jackson, Konjengbam Sarda Devi, Subhra Saikat Roy, Akoijam Ratankumar Singh, Raghuveer Singh, Amrita Banerjee, Sudhir Kumar, Arati Ningombam, Dnyaneshwar Madhukar Firake, Thokchom Surjit Singh. Simple template-based reverse transcription-recombinase polymerase amplification assay for routine diagnosis of citrus tristeza virus. Letters in applied microbiology. 2023 Jan; 76(1):. doi: 10.1093/lambio/ovac060. [PMID: 36688775]
Xiaofang Guo, Yu Gao, Wei Han, Guohui Zhao, Guixiang Zhang, Dandan Liu. Effect of multiple washing operations on the removal of potentially toxic metals from an alkaline farmland soil and the strategy for agricultural reuse. Environmental science and pollution research international. 2023 Jan; 30(1):739-751. doi: 10.1007/s11356-022-22126-5. [PMID: 35902529]
Paul Nyalo, George Omwenga, Mathew Ngugi. Quantitative Phytochemical Profile and In Vitro Antioxidant Properties of Ethyl Acetate Extracts of Xerophyta spekei (Baker) and Grewia tembensis (Fresen). Journal of evidence-based integrative medicine. 2023 Jan; 28(?):2515690X231165096. doi: 10.1177/2515690x231165096. [PMID: 36945829]
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Maryam Mazaheri-Tirani, Ashraf Kashani, Mehrana Koohi-Dehkordi. The role of iron nanoparticles on morpho-physiological traits and genes expression (IRT1 and CAT) in rue (Ruta graveolens). Plant molecular biology. 2022 Sep; 110(1-2):147-160. doi: 10.1007/s11103-022-01292-7. [PMID: 35793007]
Ge Guo, Jie Xiao, Byoung Ryong Jeong. Iron Source and Medium pH Affect Nutrient Uptake and Pigment Content in Petunia hybrida 'Madness Red' Cultured In Vitro. International journal of molecular sciences. 2022 Aug; 23(16):. doi: 10.3390/ijms23168943. [PMID: 36012209]
Thomas Boehm, Marion Alix, Karin Petroczi, Serhii Vakal, Elisabeth Gludovacz, Nicole Borth, Tiina A Salminen, Bernd Jilma. Nafamostat is a Potent Human Diamine Oxidase Inhibitor Possibly Augmenting Hypersensitivity Reactions during Nafamostat Administration. The Journal of pharmacology and experimental therapeutics. 2022 08; 382(2):113-122. doi: 10.1124/jpet.122.001248. [PMID: 35688477]
Rachel Aakerøy, Charlotte L Stokes, Marija Tomić, Solfrid Hegstad, Ann Helen Kristoffersen, Hanne Ellekjær, Jan Schjøtt, Olav Spigset, Arne Helland. Serum or Plasma for Quantification of Direct Oral Anticoagulants?. Therapeutic drug monitoring. 2022 Aug; 44(4):578-584. doi: 10.1097/ftd.0000000000000956. [PMID: 35051972]
Naomi C Buntsma, Aleksandra Gąsecka, Yvo B W E M Roos, Ton G van Leeuwen, Edwin van der Pol, Rienk Nieuwland. EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling. Platelets. 2022 Jul; 33(5):764-771. doi: 10.1080/09537104.2021.1991569. [PMID: 34697987]
Aoyu Li, Huahua Yu, Rongfeng Li, Yang Yue, Chunlin Yu, Hao Geng, Song Liu, Ronge Xing, Pengcheng Li. Jellyfish Nemopilema nomurai causes myotoxicity through the metalloprotease component of venom. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022 Jul; 151(?):113192. doi: 10.1016/j.biopha.2022.113192. [PMID: 35644119]
James Warwick, Jennifer Holness. Measurement of Glomerular Filtration Rate. Seminars in nuclear medicine. 2022 07; 52(4):453-466. doi: 10.1053/j.semnuclmed.2021.12.005. [PMID: 35063168]
Yixiong Yang, Jiarong Liao, Yahui Chen, Yuan Tian, Qibing Chen, Suping Gao, Zhenghua Luo, Xiaofang Yu, Ting Lei, Mingyan Jiang. Efficiency of heterogeneous chelating agents on the phytoremediation potential and growth of Sasa argenteostriata (Regel) E.G. Camus on Pb-contaminated soil. Ecotoxicology and environmental safety. 2022 Jun; 238(?):113603. doi: 10.1016/j.ecoenv.2022.113603. [PMID: 35551046]
Hongzi Chen, Pan Huang, Yan Zhang. Three-Dimensional, Serum-Free Culture System for Lacrimal Gland Stem Cells. Journal of visualized experiments : JoVE. 2022 06; ?(184):. doi: 10.3791/63585. [PMID: 35723466]
Yaping Duan, Ying Zhang, Bing Zhao. Lead, zinc tolerance mechanism and phytoremediation potential of Alcea rosea (Linn.) Cavan. and Hydrangea macrophylla (Thunb.) Ser. and ethylenediaminetetraacetic acid effect. Environmental science and pollution research international. 2022 Jun; 29(27):41329-41343. doi: 10.1007/s11356-021-18243-2. [PMID: 35088277]
Qinglin Li, Hui Xu, Wentao Zhang, Jingjing Sun, Yingchao Yue. Extraction of cucumber phloem sap based on the capillary-air pressure principle. BioTechniques. 2022 06; 72(6):233-243. doi: 10.2144/btn-2021-0101. [PMID: 35410484]
Mazen F Alkahtany, Khalid H Almadi. Radicular canal disinfection using photodynamic therapy and sodium hypochlorite following three chelating agents' green tea extract, grape extract, and EDTA on the push-out bond strength of epoxy resin-based sealer. Photodiagnosis and photodynamic therapy. 2022 Jun; 38(?):102809. doi: 10.1016/j.pdpdt.2022.102809. [PMID: 35288318]
Imran Khan, Muhammad Iqbal, Syed Hammad Raza, Sumera Anwar, Muhammad Ashraf, Fahad Shafiq. Tartaric acid soil-amendment increases phytoextraction potential through root to shoot transfer of lead in turnip. Chemosphere. 2022 Jun; 296(?):134055. doi: 10.1016/j.chemosphere.2022.134055. [PMID: 35196532]
Carola Ledderose, Eleftheria-Angeliki Valsami, Wolfgang G Junger. Optimized HPLC method to elucidate the complex purinergic signaling dynamics that regulate ATP, ADP, AMP, and adenosine levels in human blood. Purinergic signalling. 2022 06; 18(2):223-239. doi: 10.1007/s11302-022-09842-w. [PMID: 35132577]
Khushboo Katharotiya, Gajanan Shinde, Dhaval Katharotiya, Santosh Shelke, Rakesh Patel, Deepak Kulkarni, Prabhakar Panzade. Development, evaluation and biodistribution of stealth liposomes of 5-fluorouracil for effective treatment of breast cancer. Journal of liposome research. 2022 Jun; 32(2):146-158. doi: 10.1080/08982104.2021.1905661. [PMID: 33847220]
Nguyen Ngoc Son Hai, Peter Sanderson, Fangjie Qi, Jianhua Du, Nguyen Ngoc Nong, Nanthi Bolan, Ravi Naidu. Effects of chelates (EDTA, EDDS, NTA) on phytoavailability of heavy metals (As, Cd, Cu, Pb, Zn) using ryegrass (Lolium multiflorum Lam.). Environmental science and pollution research international. 2022 Jun; 29(28):42102-42116. doi: 10.1007/s11356-022-19877-6. [PMID: 35366209]
Ying Wang, Guangxu Qu, Li Yin, Qingzhi Liu, Ruimei Yang, Lihua Lu. Ratiometric detection of transcription factor based on Europium(III) complex-doped silicon nanoparticles and a G-quadruplex-selective Iridium(III) complex. Analytica chimica acta. 2022 May; 1209(?):339855. doi: 10.1016/j.aca.2022.339855. [PMID: 35569852]
Antonella Giliberti, Annalisa Curcio, Nicola Marchitto, Luca Di Lullo, Fulvia Paolozzi, Fabiana Nano, Michele Pironti, Gianfranco Raimondi. Comparison of Ferric Sodium EDTA in Combination with Vitamin C, Folic Acid, Copper Gluconate, Zinc Gluconate, and Selenomethionine as Therapeutic Option for Chronic Kidney Disease Patients with Improvement in Inflammatory Status. Nutrients. 2022 May; 14(10):. doi: 10.3390/nu14102116. [PMID: 35631257]
Chaicharoen Tantanate, Supavat Talabthong, Phenluck Lamyai. Kanamycin Supplement for the Disaggregation of Platelet Clumps in EDTA-Dependent Pseudothrombocytopenia Specimens. Laboratory medicine. 2022 May; 53(3):e69-e73. doi: 10.1093/labmed/lmab090. [PMID: 34668538]
Simon J Whitehead, Katie Chadwick, Clare Ford, Ramesh Giri, Heyman Luckraz, Rousseau Gama. Comparative Evaluation of Two NGAL Automated Immunoassays in Urine and Plasma. The journal of applied laboratory medicine. 2022 05; 7(3):747-761. doi: 10.1093/jalm/jfab167. [PMID: 34993540]
Tejas Kalaria, Jonathan Fenn, Richard Whitmill, Clare Ford, Rousseau Gama. Acid freezes uricolysis in addition to glycolysis: Utility of fluoride-EDTA-citrate tube in the measurement of uric acid for patients administered rasburicase. Annals of clinical biochemistry. 2022 05; 59(3):178-182. doi: 10.1177/00045632211066275. [PMID: 34989247]
Nasibeh Karimi, Razieh Dalirfardouei, Tomás Dias, Jan Lötvall, Cecilia Lässer. Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples. Journal of extracellular vesicles. 2022 05; 11(5):e12213. doi: 10.1002/jev2.12213. [PMID: 35524458]
Benoit Loup, François André, Justine Avignon, Marion Lhuaire, Vivian Delcourt, Agnès Barnabé, Patrice Garcia, Marie-Agnès Popot, Ludovic Bailly-Chouriberry. miRNAs detection in equine plasma by quantitative polymerase chain reaction for doping control: Assessment of blood sampling and study of eca-miR-144 as potential erythropoiesis stimulating agent biomarker. Drug testing and analysis. 2022 May; 14(5):953-962. doi: 10.1002/dta.3047. [PMID: 33860991]
Clara Wai-Shan Lo, Teresa Kam-Chi Tsui, Ronald Ching-Wan Ma, Michael Ho-Ming Chan, Chung-Shun Ho. Quantitation of plasma angiotensin II in healthy Chinese subjects by a validated liquid chromatography tandem mass spectrometry method. Biomedical chromatography : BMC. 2022 May; 36(5):e5318. doi: 10.1002/bmc.5318. [PMID: 34981551]
Veronica Ghini, Gaia Meoni, Lorenzo Pelagatti, Tommaso Celli, Francesca Veneziani, Fabrizia Petrucci, Vieri Vannucchi, Laura Bertini, Claudio Luchinat, Giancarlo Landini, Paola Turano. Profiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients. PLoS pathogens. 2022 04; 18(4):e1010443. doi: 10.1371/journal.ppat.1010443. [PMID: 35446921]
Takashi Kato. Immunofluorescence Detection of Plasma Membranous PTEN in Cultured Cells. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2022 04; 70(4):289-297. doi: 10.1369/00221554221082539. [PMID: 35199573]
Andreas Greinacher, Linda Schönborn, Florian Siegerist, Leif Steil, Raghavendra Palankar, Stefan Handtke, Alexander Reder, Thomas Thiele, Konstanze Aurich, Karen Methling, Michael Lalk, Uwe Völker, Nicole Endlich. Pathogenesis of vaccine-induced immune thrombotic thrombocytopenia (VITT). Seminars in hematology. 2022 04; 59(2):97-107. doi: 10.1053/j.seminhematol.2022.02.004. [PMID: 35512907]
A L Hirsch, J M Fletcher, M A Mitchell. Effects of EDTA on chemiluminescent immunoassay measurement of ACTH, cortisol, and thyroid hormones in dogs. Domestic animal endocrinology. 2022 04; 79(?):106707. doi: 10.1016/j.domaniend.2021.106707. [PMID: 35016023]
Zhenhuan Song, Ting Liu, Haoqiang Lai, Xiaofeng Meng, Liu Yang, Jianyu Su, Tianfeng Chen. A Universally EDTA-Assisted Synthesis of Polytypic Bismuth Telluride Nanoplates with a Size-Dependent Enhancement of Tumor Radiosensitivity and Metabolism In Vivo. ACS nano. 2022 03; 16(3):4379-4396. doi: 10.1021/acsnano.1c10663. [PMID: 35175721]
Filippo Ravalli, Xavier Vela Parada, Francisco Ujueta, Rachel Pinotti, Kevin J Anstrom, Gervasio A Lamas, Ana Navas-Acien. Chelation Therapy in Patients With Cardiovascular Disease: A Systematic Review. Journal of the American Heart Association. 2022 03; 11(6):e024648. doi: 10.1161/jaha.121.024648. [PMID: 35229619]
Dániel Bereczki, Béla Nagy, Adrienne Kerényi, Gábor Nagy, Krisztina Szarka, Katalin Kristóf, Balázs Szalay, Barna Vásárhelyi, Harjit P Bhattoa, János Kappelmayer. EDTA-Induced Pseudothrombocytopenia up to 9 Months after Initial COVID-19 Infection Associated with Persistent Anti-SARS-CoV-2 IgM/IgG Seropositivity. Laboratory medicine. 2022 Mar; 53(2):206-209. doi: 10.1093/labmed/lmab050. [PMID: 34415328]
Zahra Bakhshi Golestani, Salman Soltani, Mahmoud Reza Kalantari, Hamid Reza Ghorbani, Atena Aghaee. Rare Case of Small Cell Metastatic Prostatic Adenocarcinoma, Properly Staged by 68Ga-PSMA PET/CT Scan. Clinical nuclear medicine. 2022 Mar; 47(3):e259-e261. doi: 10.1097/rlu.0000000000004033. [PMID: 35025791]
Michael Boehm, Marjolein Bonthuis, Christoph Aufricht, Nina Battelino, Anna Bjerre, Vidar O Edvardsson, Maria Herthelius, Holger Hubmann, Timo Jahnukainen, Huib de Jong, Guido F Laube, Francesca Mattozzi, Elena A Molchanova, Marina Muñoz, Aytul Noyan, Lars Pape, Nikoleta Printza, George Reusz, Gwenaelle Roussey, Jacek Rubik, Brankica Spasojevic'-Dimitrijeva, Tomas Seeman, Nicholas Ware, Enrico Vidal, Jérôme Harambat, Kitty J Jager, Jaap Groothoff. Kidney Transplantation in Small Children: Association Between Body Weight and Outcome-A Report From the ESPN/ERA-EDTA Registry. Transplantation. 2022 03; 106(3):607-614. doi: 10.1097/tp.0000000000003771. [PMID: 33795596]
Denise Schrama, Cláudia Raposo de Magalhães, Marco Cerqueira, Raquel Carrilho, Ana Paula Farinha, Ana M Rosa da Costa, Amparo Gonçalves, Annette Kuehn, Dominique Revets, Sébastien Planchon, Sofia Engrola, Pedro M Rodrigues. Effect of creatine and EDTA supplemented diets on European seabass (Dicentrarchus labrax) allergenicity, fish muscle quality and omics fingerprint. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 2022 03; 41(?):100941. doi: 10.1016/j.cbd.2021.100941. [PMID: 34814088]
Jan-Henning Schierz, Ismet Sarikaya, Ahmed N Albatineh, Ali Sarikaya. Assessing the Correlation Between 68Ga-PSMA-11 Renal PET Parameters and Renal Function Tests. Journal of nuclear medicine technology. 2022 Mar; 50(1):43-48. doi: 10.2967/jnmt.121.262462. [PMID: 34330809]
Guochang Wang, Haiyan Hong, Jie Zang, Qingxing Liu, Yuanyuan Jiang, Xinrong Fan, Zhaohui Zhu, Lin Zhu, Hank F Kung. Head-to-head comparison of [68 Ga]Ga-P16-093 and [68 Ga]Ga-PSMA-617 in dynamic PET/CT evaluation of the same group of recurrent prostate cancer patients. European journal of nuclear medicine and molecular imaging. 2022 02; 49(3):1052-1062. doi: 10.1007/s00259-021-05539-1. [PMID: 34557930]
Pattarin Leelaphiwat, Chayanat Pechprankan, Paphawin Siripho, Nattinee Bumbudsanpharoke, Nathdanai Harnkarnsujarit. Effects of nisin and EDTA on morphology and properties of thermoplastic starch and PBAT biodegradable films for meat packaging. Food chemistry. 2022 Feb; 369(?):130956. doi: 10.1016/j.foodchem.2021.130956. [PMID: 34479016]
Jacquelien J Hillebrand, Li Zhou, Marilee A Marcinkus, Maria Datwyler, Susan H Gawel, Frans Martens, Gerard J Davis, Annemieke C Heijboer. Instability of corticotropin during long-term storage - myth or reality?. Clinical chemistry and laboratory medicine. 2022 01; 60(1):60-65. doi: 10.1515/cclm-2021-0818. [PMID: 34643074]
Hans Pottel, Karolien Goffin, Liesbeth De Waele, Elena Levtchenko, Pierre Delanaye. 51Cr-EDTA plasma clearance in children: One, two, or multiple samples?. Medicine. 2022 Jan; 101(3):e28608. doi: 10.1097/md.0000000000028608. [PMID: 35060531]
Louis Nevejan, Thomas Strypens, Mathias Van Nieuwenhove, An Boel, Lien Cattoir, Peter Meeus, Xavier Bossuyt, Nikolaas De Neve, Lieve Van Hoovels. Prognostic value of circulating calprotectin levels on the clinical course of COVID-19 differs between serum, heparin, EDTA and citrate sample types. Clinica chimica acta; international journal of clinical chemistry. 2022 Jan; 525(?):54-61. doi: 10.1016/j.cca.2021.12.011. [PMID: 34919937]
Wisdom P Nakanga, Priscilla Balungi, Anxious J Niwaha, Beverly M Shields, Peter Hughes, Rob C Andrews, Tim J Mc Donald, Moffat J Nyirenda, Andrew T Hattersley. Alternative pre-analytic sample handling techniques for glucose measurement in the absence of fluoride tubes in low resource settings. PloS one. 2022; 17(2):e0264432. doi: 10.1371/journal.pone.0264432. [PMID: 35226681]
Rimanshee Arya, Vishal Prashar, Mukesh Kumar. Evaluating Stability and Activity of SARS-CoV-2 PLpro for High-throughput Screening of Inhibitors. Molecular biotechnology. 2022 Jan; 64(1):1-8. doi: 10.1007/s12033-021-00383-y. [PMID: 34420183]
Burcin Karasah Erkek, Özgür Ömür, Serdar Özkök, Burak Turna. COVID-19 Lung Findings Detected by 68Ga-PSMA PET/CT for Staging Purposes in Patients With Prostate Cancer. Clinical nuclear medicine. 2022 Jan; 47(1):e17-e19. doi: 10.1097/rlu.0000000000003723. [PMID: 34028424]
Salwinder Singh Dhaliwal, Vivek Sharma, Parminder Kaur Taneja, Arvind Kumar Shukla, Lovedeep Kaur, Gayatri Verma, Vibha Verma, Jagdish Singh. Effect of cadmium and ethylenediamine tetraacetic acid supplementation on cadmium accumulation by roots of Brassica species in Cd spiked soil. Environmental science and pollution research international. 2022 Jan; 29(4):6000-6009. doi: 10.1007/s11356-021-16084-7. [PMID: 34431059]
H Nawaz, A Ali, M H Saleem, A Ameer, A Hafeez, K Alharbi, A Ezzat, A Khan, M Jamil, G Farid. Comparative effectiveness of EDTA and citric acid assisted phytoremediation of Ni contaminated soil by using canola (Brassica napus). Brazilian journal of biology = Revista brasleira de biologia. 2022; 82(?):e261785. doi: 10.1590/1519-6984.261785. [PMID: 35703635]
Ujala Ejaz, Shujaul Mulk Khan, Muhammad Aqeel, Noreen Khalid, Wajiha Sarfraz, Nayab Naeem, Heesup Han, Jongsik Yu, Gong Yue, António Raposo. Use of Parthenium hysterophorus with synthetic chelator for enhanced uptake of cadmium and lead from contaminated soils-a step toward better public health. Frontiers in public health. 2022; 10(?):1009479. doi: 10.3389/fpubh.2022.1009479. [PMID: 36311603]
Ting Chu, Xiufeng Ni, Yanhua Zhu. EDTA Combined with C-Pilot Files and Microultrasound for Root Canal Calcification: Dredging Effect and Safety Analysis. Computational and mathematical methods in medicine. 2022; 2022(?):1911448. doi: 10.1155/2022/1911448. [PMID: 36267312]
Melis Oflas, Yasemin Ozluk, Oner Sanli, Zeynep Gozde Ozkan, Serkan Kuyumcu. 68Ga-PSMA Uptake Patterns of Clear Cell Renal Carcinoma Across Different Histopathological Subtypes. Clinical nuclear medicine. 2022 Jan; 47(1):e45-e46. doi: 10.1097/rlu.0000000000003814. [PMID: 34284482]
Haiyan Guan, Li Dong, Yan Zhang, Shubing Bai, Li Yan. GLDA and EDTA assisted phytoremediation potential of Sedum hybridum 'Immergrunchen' for Cd and Pb contaminated soil. International journal of phytoremediation. 2022; 24(13):1395-1404. doi: 10.1080/15226514.2022.2031865. [PMID: 35166632]
Abdur Rauf, Sami Bawazeer, Jesús Herrera-Bravo, Muslim Raza, Humaira Naz, Somia Gul, Naveed Muhammad, Zainab M Almarhoon, Yahia N Mabkhot, Mohamed Fawzy Ramadan, William N Setzer, Sevgi Durna Daştan, Shafi Mahmud, Javad Sharifi-Rad. Potent In Vitro Phosphodiesterase 1 Inhibition of Flavone Isolated from Pistacia integerrima Galls. BioMed research international. 2022; 2022(?):6116003. doi: 10.1155/2022/6116003. [PMID: 35083331]