Cycloheximide (BioDeep_00000000142)

   

Chemicals and Drugs Antitumor activity


代谢物信息卡片


2,6-PIPERIDINEDIONE, 4-(2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)-, (1S-(1.ALPHA.(S*),3.ALPHA.,5.BETA.))-

化学式: C15H23NO4 (281.1627)
中文名称: 3-[2-(3,5-二甲基-2-氧代环己基)-2-羧基乙基]戊二酰胺, 放线菌酮
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 10.92%

分子结构信息

SMILES: CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C
InChI: InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1

描述信息

Cycloheximide appears as colorless crystals. Used as a fungicide and as a anticancer drug. (EPA, 1998)
Cycloheximide is a dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. It has a role as a bacterial metabolite, a protein synthesis inhibitor, a neuroprotective agent, an anticoronaviral agent and a ferroptosis inhibitor. It is a member of piperidones, a piperidine antibiotic, an antibiotic fungicide, a dicarboximide, a secondary alcohol and a cyclic ketone. It is functionally related to a piperidine-2,6-dione.
Cycloheximide is a natural product found in Streptomyces, Streptomyces griseus, and Streptomyces pulveraceus with data available.
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
Origin: Microbe; SubCategory_DNP: Alkaloids derived from lysine, Piperidine alkaloids
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.773
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.776
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.777
[Raw Data] CBA53_Cycloheximid_pos_50eV.txt
[Raw Data] CBA53_Cycloheximid_pos_20eV.txt
[Raw Data] CBA53_Cycloheximid_pos_10eV.txt
[Raw Data] CBA53_Cycloheximid_pos_40eV.txt
[Raw Data] CBA53_Cycloheximid_pos_30eV.txt

同义名列表

105 个代谢物同义名

2,6-PIPERIDINEDIONE, 4-(2-(3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)-, (1S-(1.ALPHA.(S*),3.ALPHA.,5.BETA.))-; [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-4-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione; 2,6-Piperidinedione, 4-(2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-, (1S-(1alpha(S*),3alpha,5beta))-; (1S-(1alpha(S*),3alpha,5beta))-4-(2-(3,5-Dimethyl-2-oxo-cyclohexyl))-2-hydroxyethyl-2,6-piperidinedione; 2, 4-[2-(3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]-, [1S-[1.alpha.(S*),3.alpha.,5.beta.]]-; 4-[(2R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]azaperhydro ine-2,6-dione; 2,6-Piperidinedione, 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]-; 4-((2R)-2-((1S,3S,5S)-(3,5-Dimethyl-2-oxocyclohexyl))-2-hydroxyethyl)piperidine-2,6-dione; 4-[(2R)-2-[(1S,3S,5R)-3,5-dimethyl-2-oxo-cyclohexyl]-2-hydroxy-ethyl]piperidine-2,6-dione; 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxo-cyclohexyl]-2-hydroxy-ethyl]piperidine-2,6-dione; 2,6-Piperidinedione, 4-((2R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-; 4-((2R)-2-((1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)-2,6-PIPERIDINEDIONE; 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione; 4-((2R)-2-((1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL)-2-HYDROXYETHYL)PIPERIDINE-2,6-DIONE; 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione; 4-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)piperidine-2,6-dione; 3-[(R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]glutarimide; 3-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; 3-(2R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethylglutarimide; 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione; .beta.-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide; beta-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide; 3-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide; Cycloheximide, Antibiotic for Culture Media Use Only; Cycloheximide, Biotechnology Performance Certified; Cycloheximide, PESTANAL(R), analytical standard; 5-21-13-00434 (Beilstein Handbook Reference); Cycloheximide, from microbial, >=94\\% (TLC); Cycloheximide, Streptomyces griseus; WLN: T6VMVTJ E1YQ- BL6VTJ D1 F1; Cycloheximide, >=93.0\\% (HPLC); Cicloheximida [INN-Spanish]; YPHMISFOHDHNIV-FSZOTQKASA-N; Cicloheximidum [INN-Latin]; 4-[2-(3,6-piperidinedione; Actidione;Naramycin A;CHX; Cycloheximide [BSI:ISO]; CICLOHEXIMIDE [MART.]; Cycloheximide [USAN]; CYCLOHEXIMIDE [HSDB]; Cycloheximide (USAN); CYCLOHEXIMIDE [ISO]; Cicloheximide (INN); Cicloheximide [INN]; CYCLOHEXIMIDE [MI]; Prestwick0_000790; Prestwick2_000790; Prestwick3_000790; Prestwick1_000790; Spectrum4_000914; Spectrum5_001635; Spectrum3_001510; Neocycloheximide; Aktidion [Czech]; Spectrum2_000900; Tox21_113580_1; Cicloheximidum; Acti-dione TGF; Acti-dione BR; Acti-dione PM; DivK1c_000050; Actidione TGF; Cyclohexamide; Cyclohemimide; Cicloheximida; Cicloheximide; Cycloheximide; BPBio1_000990; Actidione PM; KBio1_000050; NCI60_001540; Tox21_303652; Cycloheximid; KBio2_006960; KBio2_004392; Tox21_113580; Actidione BR; Zykloheximid; KBio3_002659; Tox21_201158; KBio2_001824; NARAMYCIN A; CAS-66-81-9; IDI1_000050; Acti-Dione; ?Actidione; Naramycin; ksc-8-190; AI3-15541; Hizarocin; C15H23NO4; Actispray; NM-MCD 80; Actidione; Acti-Aid; Aktidion; Actidion; Actidone; Kaken; CHX; TZA; CX; Isocycloheximide; Cycloheximide



数据库引用编号

45 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AKT1, ALB, ANXA5, CASP3, CASP8, CDKN1A, MAPK14, MTOR, MYC, NOS2, PIK3C3, PRKX
Peripheral membrane protein 2 ANXA5, MTOR
Endoplasmic reticulum membrane 2 HSP90B1, MTOR
Cytoplasmic vesicle, autophagosome 1 PIK3C3
Nucleus 12 AKT1, ALB, CASP3, CASP8, CDKN1A, FOS, HSP90B1, MAPK14, MTOR, MYC, NOS2, PRKX
autophagosome 1 PIK3C3
cytosol 13 AKT1, ALB, ANXA5, CASP3, CASP8, CDKN1A, FOS, HSP90B1, MAPK14, MTOR, NOS2, PIK3C3, PRKCQ
dendrite 1 MTOR
nuclear body 1 CDKN1A
phagocytic vesicle 1 MTOR
phosphatidylinositol 3-kinase complex, class III 1 PIK3C3
centrosome 1 ALB
nucleoplasm 10 AKT1, CASP3, CASP8, CDKN1A, FOS, MAPK14, MTOR, MYC, NOS2, PRKX
RNA polymerase II transcription regulator complex 1 FOS
Cell membrane 2 AKT1, TNF
Cytoplasmic side 1 MTOR
lamellipodium 2 AKT1, CASP8
Golgi apparatus membrane 1 MTOR
cell cortex 1 AKT1
cell surface 1 TNF
glutamatergic synapse 4 AKT1, CASP3, MAPK14, PIK3C3
Golgi apparatus 1 ALB
Golgi membrane 2 INS, MTOR
lysosomal membrane 2 EGF, MTOR
neuronal cell body 2 CASP3, TNF
postsynapse 1 AKT1
sarcolemma 1 ANXA5
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 NOS2
Lysosome 1 MTOR
endosome 1 PIK3C3
plasma membrane 6 AKT1, EGF, IFNLR1, NOS2, PRKCQ, TNF
Membrane 8 AKT1, ANXA5, EGF, HSP90B1, IFNLR1, MTOR, MYC, PIK3C3
extracellular exosome 4 ALB, ANXA5, EGF, HSP90B1
Lysosome membrane 1 MTOR
endoplasmic reticulum 3 ALB, FOS, HSP90B1
extracellular space 5 ALB, EGF, IL6, INS, TNF
perinuclear region of cytoplasm 3 CDKN1A, HSP90B1, NOS2
mitochondrion 2 CASP8, MAPK14
protein-containing complex 6 AKT1, ALB, CASP8, CDKN1A, HSP90B1, MYC
Microsome membrane 1 MTOR
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 IFNLR1
Secreted 3 ALB, IL6, INS
extracellular region 8 ALB, ANXA5, EGF, HSP90B1, IL6, INS, MAPK14, TNF
Mitochondrion outer membrane 1 MTOR
mitochondrial outer membrane 2 CASP8, MTOR
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
external side of plasma membrane 2 ANXA5, TNF
microtubule cytoskeleton 1 AKT1
nucleolus 2 CDKN1A, MYC
midbody 2 HSP90B1, PIK3C3
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cell projection, lamellipodium 1 CASP8
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 1 TNF
focal adhesion 2 ANXA5, HSP90B1
spindle 1 AKT1
GABA-ergic synapse 1 PIK3C3
Peroxisome 2 NOS2, PIK3C3
peroxisomal matrix 1 NOS2
Nucleus, PML body 1 MTOR
PML body 1 MTOR
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 2 ANXA5, HSP90B1
axoneme 1 PIK3C3
nuclear speck 1 MAPK14
Late endosome 1 PIK3C3
Zymogen granule membrane 1 ANXA5
ciliary basal body 2 AKT1, ALB
chromatin 2 FOS, MYC
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 PIK3C3
cytoskeleton 1 CASP8
centriole 1 ALB
Nucleus, nucleolus 1 MYC
spindle pole 2 ALB, MAPK14
blood microparticle 1 ALB
nuclear envelope 2 MTOR, MYC
Endomembrane system 1 MTOR
endosome lumen 1 INS
phagophore assembly site 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type I 1 PIK3C3
phosphatidylinositol 3-kinase complex, class III, type II 1 PIK3C3
Nucleus, nucleoplasm 1 MYC
Melanosome 1 HSP90B1
cell body 1 CASP8
sperm plasma membrane 1 HSP90B1
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 2 INS, MAPK14
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, HSP90B1, IL6, INS
nuclear matrix 1 FOS
platelet alpha granule lumen 2 ALB, EGF
transport vesicle 1 INS
RNA polymerase II transcription repressor complex 1 MYC
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
presynaptic endosome 1 PIK3C3
aggresome 1 PRKCQ
vesicle membrane 1 ANXA5
clathrin-coated endocytic vesicle membrane 1 EGF
Sarcoplasmic reticulum lumen 1 HSP90B1
protein-DNA complex 1 FOS
CD95 death-inducing signaling complex 1 CASP8
death-inducing signaling complex 2 CASP3, CASP8
ripoptosome 1 CASP8
Rough endoplasmic reticulum 1 MYC
Cytoplasmic vesicle, phagosome 1 MTOR
cyclin-dependent protein kinase holoenzyme complex 1 CDKN1A
postsynaptic endosome 1 PIK3C3
endocytic vesicle lumen 1 HSP90B1
transcription factor AP-1 complex 1 FOS
Myc-Max complex 1 MYC
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
Autolysosome 1 PIK3C3
interleukin-6 receptor complex 1 IL6
endoplasmic reticulum chaperone complex 1 HSP90B1
endothelial microparticle 1 ANXA5
PCNA-p21 complex 1 CDKN1A
ciliary transition fiber 1 ALB
interleukin-28 receptor complex 1 IFNLR1
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
nucleoplasmic reticulum 1 MYC


文献列表

  • Hamdah M Al Nebaihi, Neal M Davies, Dion R Brocks. {Pharmacokinetics of cycloheximide in rats and evaluation of its effect as a blocker of intestinal lymph formation. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2023 Oct; ?(?):. doi: 10.1016/j.ejpb.2023.10.016. [PMID: 37884159]
  • Srinivas Reddy Jitta, Salwa, Navya Ajitkumar Bhaskaran, Shirleen Miriam Marques, Lalit Kumar, Sri Pragnya Cheruku, Vanishree Rao, Pravesh Sharma, Onkar Prakash Kulkarni. Enhanced tissue distribution of ritonavir-loaded nanostructured lipid carriers-recommending its dose reduction. Drug delivery and translational research. 2023 Jul; ?(?):. doi: 10.1007/s13346-023-01386-9. [PMID: 37402943]
  • Qing He, Changzhi Yu, Yang Li, Peng Hao, Hantao Mai, Ruilian Guo, Guifang Zhong, Kelin Zhang, Chipiu Wong, Qian Chen, Yantao Chen. ERRα contributes to HDAC6-induced chemoresistance of osteosarcoma cells. Cell biology and toxicology. 2023 06; 39(3):813-825. doi: 10.1007/s10565-021-09651-8. [PMID: 34524571]
  • Li Lin, Qingyong Chen, Yue Dai, Yufeng Xia. Self-Nanoemulsifying Drug Delivery System for Enhanced Bioavailability of Madecassic Acid: In vitro and in vivo Evaluation. International journal of nanomedicine. 2023; 18(?):2345-2358. doi: 10.2147/ijn.s408115. [PMID: 37187996]
  • Haojun Xiong, Dandan Zheng, Ying Liu, Lihai Ma, Lingzhan Meng, Zhenzhou Yang, Zhixiang Yang. Activation of the β‑TrCP/IκBα/inflammation axis limits the sensitivity of liver cancer cells to neddylation inhibition. Oncology reports. 2022 Nov; 48(5):. doi: 10.3892/or.2022.8416. [PMID: 36169173]
  • Sherif Rashad, Shane R Byrne, Daisuke Saigusa, Jingdong Xiang, Yuan Zhou, Liyin Zhang, Thomas J Begley, Teiji Tominaga, Kuniyasu Niizuma. Codon Usage and mRNA Stability are Translational Determinants of Cellular Response to Canonical Ferroptosis Inducers. Neuroscience. 2022 10; 501(?):103-130. doi: 10.1016/j.neuroscience.2022.08.009. [PMID: 35987429]
  • Lumen Chao, Yongsig Kim, Sarah J Gilmour, Michael F Thomashow. Temperature modulation of CAMTA3 gene induction activity is mediated through the DNA binding domain. The Plant journal : for cell and molecular biology. 2022 10; 112(1):235-248. doi: 10.1111/tpj.15944. [PMID: 35960653]
  • Justine Kniert, Theodore Dos Santos, Heather E Eaton, Woo Jung Cho, Greg Plummer, Maya Shmulevitz. Reovirus uses temporospatial compartmentalization to orchestrate core versus outercapsid assembly. PLoS pathogens. 2022 09; 18(9):e1010641. doi: 10.1371/journal.ppat.1010641. [PMID: 36099325]
  • Ailin Yang, Qi Wu, Qimei Chen, Jingyi Yang, Haoran Li, Yufan Tao, Anmei Wang, Yaxue Sun, Jiayu Zhang. Cinobufagin restrains the growth and triggers DNA damage of human hepatocellular carcinoma cells via proteasome-dependent degradation of thymidylate synthase. Chemico-biological interactions. 2022 Jun; 360(?):109938. doi: 10.1016/j.cbi.2022.109938. [PMID: 35427566]
  • Hamdah M Al Nebaihi, Tyson S Le, Neal M Davies, Dion R Brocks. Analysis of cycloheximide in rat specimens using liquid chromatography with tandem massspectrometry detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2022 Feb; 1190(?):123112. doi: 10.1016/j.jchromb.2022.123112. [PMID: 35032893]
  • Selma Ríos-Meléndez, Emmanuel Valadez-Hernández, Claudio Delgadillo, Maria L Luna-Guevara, Mario A Martínez-Núñez, Mishael Sánchez-Pérez, José L Martínez-Y-Pérez, Analilia Arroyo-Becerra, Luis Cárdenas, Martha Bibbins-Martínez, Ignacio E Maldonado-Mendoza, Miguel Angel Villalobos-López. Pseudocrossidium replicatum (Taylor) R.H. Zander is a fully desiccation-tolerant moss that expresses an inducible molecular mechanism in response to severe abiotic stress. Plant molecular biology. 2021 Nov; 107(4-5):387-404. doi: 10.1007/s11103-021-01167-3. [PMID: 34189708]
  • Rui Huang, Lijun Zhang, Jinmei Jin, Yudong Zhou, Hongwei Zhang, Chao Lv, Dong Lu, Ye Wu, Hong Zhang, Sanhong Liu, Hongzhuan Chen, Xin Luan, Weidong Zhang. Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction. Acta pharmaceutica Sinica. B. 2021 Nov; 11(11):3481-3492. doi: 10.1016/j.apsb.2021.05.009. [PMID: 34900531]
  • Amalia H Megarioti, Cecilia Primo, George C Kapetanakis, Alexandros Athanasopoulos, Vicky Sophianopoulou, Bruno André, Christos Gournas. The Bul1/2 Alpha-Arrestins Promote Ubiquitylation and Endocytosis of the Can1 Permease upon Cycloheximide-Induced TORC1-Hyperactivation. International journal of molecular sciences. 2021 Sep; 22(19):. doi: 10.3390/ijms221910208. [PMID: 34638549]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Kyung-Soon Lee, Edelmar Navaluna, Nicole M Marsh, Eric M Janezic, Chris Hague. Development of a Novel SNAP-Epitope Tag/Near-Infrared Imaging Assay to Quantify G Protein-Coupled Receptor Degradation in Human Cells. SLAS discovery : advancing life sciences R & D. 2021 04; 26(4):570-578. doi: 10.1177/2472555220979793. [PMID: 33402011]
  • J Romário F de Melo, Annelie Gutsch, Thomas De Caluwé, Jean-Christophe Leloup, Didier Gonze, Christian Hermans, Alex A R Webb, Nathalie Verbruggen. Magnesium maintains the length of the circadian period in Arabidopsis. Plant physiology. 2021 03; 185(2):519-532. doi: 10.1093/plphys/kiaa042. [PMID: 33721908]
  • Liang Zhang, Daniel DeGennaro, Guangzhong Lin, Jijie Chai, Elena D Shpak. ERECTA family signaling constrains CLAVATA3 and WUSCHEL to the center of the shoot apical meristem. Development (Cambridge, England). 2021 03; 148(5):. doi: 10.1242/dev.189753. [PMID: 33593817]
  • Camille Link, Julia D Knopf, Oriana Marques, Marius K Lemberg, Martina U Muckenthaler. The role of cellular iron deficiency in controlling iron export. Biochimica et biophysica acta. General subjects. 2021 03; 1865(3):129829. doi: 10.1016/j.bbagen.2020.129829. [PMID: 33340587]
  • Maxim V Gerashchenko, Zalan Peterfi, Sun Hee Yim, Vadim N Gladyshev. Translation elongation rate varies among organs and decreases with age. Nucleic acids research. 2021 01; 49(2):e9. doi: 10.1093/nar/gkaa1103. [PMID: 33264395]
  • Chao-Tao Tang, Qing-Wei Zhang, Shan Wu, Ming-Yu Tang, Qian Liang, Xiao-Lu Lin, Yun-Jie Gao, Zhi-Zheng Ge. Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation. Cellular and molecular life sciences : CMLS. 2020 Dec; 77(24):5207-5221. doi: 10.1007/s00018-020-03465-3. [PMID: 32008086]
  • Yu-Jeong Choi, Sol Ji Lee, Hyo In Kim, Hee Jung Lee, So Jung Kang, Tai Young Kim, Chunhoo Cheon, Seong-Gyu Ko. Platycodin D enhances LDLR expression and LDL uptake via down-regulation of IDOL mRNA in hepatic cells. Scientific reports. 2020 11; 10(1):19834. doi: 10.1038/s41598-020-76224-w. [PMID: 33199761]
  • Kyu Min Kim, Sam Seok Cho, Sung Hwan Ki. Emerging roles of ferroptosis in liver pathophysiology. Archives of pharmacal research. 2020 Oct; 43(10):985-996. doi: 10.1007/s12272-020-01273-8. [PMID: 33079307]
  • Chunxiao Li, Lu Chen, Min Song, Zhirui Fang, Lusha Zhang, Joel Wake Coffie, Liyuan Zhang, Lulu Ma, Qianyi Wang, Wenjie Yang, Leyu Fang, Shaoxia Wang, Xiumei Gao, Hong Wang. Ferulic acid protects cardiomyocytes from TNF-α/cycloheximide-induced apoptosis by regulating autophagy. Archives of pharmacal research. 2020 Aug; 43(8):863-874. doi: 10.1007/s12272-020-01252-z. [PMID: 32720163]
  • Wenjia Wang, Kook Hui Ryu, Angela Bruex, Christa Barron, John Schiefelbein. Molecular Basis for a Cell Fate Switch in Response to Impaired Ribosome Biogenesis in the Arabidopsis Root Epidermis. The Plant cell. 2020 07; 32(7):2402-2423. doi: 10.1105/tpc.19.00773. [PMID: 32371546]
  • Abril Carbajal-García, Jorge Reyes-García, María F Casas-Hernández, Edgar Flores-Soto, Verónica Díaz-Hernández, Héctor Solís-Chagoyán, Bettina Sommer, Luis M Montaño. Testosterone augments β2 adrenergic receptor genomic transcription increasing salbutamol relaxation in airway smooth muscle. Molecular and cellular endocrinology. 2020 06; 510(?):110801. doi: 10.1016/j.mce.2020.110801. [PMID: 32278021]
  • Jingshu Liu, Rachel L Taylor, Richard A Baines, Lisa Swanton, Sally Freeman, Barbara Corneo, Achchhe Patel, Alan Marmorstein, Travis Knudsen, Graeme C Black, Forbes Manson. Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium. Investigative ophthalmology & visual science. 2020 05; 61(5):28. doi: 10.1167/iovs.61.5.28. [PMID: 32421148]
  • Jian Feng Jin, Zhan Qi Wang, Qi Yu He, Jia Yi Wang, Peng Fei Li, Ji Ming Xu, Shao Jian Zheng, Wei Fan, Jian Li Yang. Genome-wide identification and expression analysis of the NAC transcription factor family in tomato (Solanum lycopersicum) during aluminum stress. BMC genomics. 2020 Apr; 21(1):288. doi: 10.1186/s12864-020-6689-7. [PMID: 32264854]
  • Jinque Luo, Felix Q Jin, Meimei Yin, Zheng Gen Jin. Regulation of SRF protein stability by an autophagy-dependent pathway. Biochemical and biophysical research communications. 2020 01; 521(2):279-284. doi: 10.1016/j.bbrc.2019.09.104. [PMID: 31668369]
  • Xinrong Ma, Fadia Ibrahim, Eun-Jeong Kim, Scott Shaver, James Becker, Fareha Razvi, Ronald L Cerny, Heriberto Cerutti. An ortholog of the Vasa intronic gene is required for small RNA-mediated translation repression in Chlamydomonas reinhardtii. Proceedings of the National Academy of Sciences of the United States of America. 2020 01; 117(1):761-770. doi: 10.1073/pnas.1908356117. [PMID: 31871206]
  • Wenji Zhang, Yang Yang, Zizheng Dong, Zhi Shi, Jian-Ting Zhang. Single-nucleotide polymorphisms in a short basic motif in the ABC transporter ABCG2 disable its trafficking out of endoplasmic reticulum and reduce cell resistance to anticancer drugs. The Journal of biological chemistry. 2019 12; 294(52):20222-20232. doi: 10.1074/jbc.ra119.008347. [PMID: 31719146]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Jingfang Sun, Ran Tao, Tianxiao Mao, Zhi Feng, Qinglong Guo, Xiaobo Zhang. The involvement of lipid raft pathway in suppression of TGFβ-mediated metastasis by tolfenamic acid in hepatocellular carcinoma cells. Toxicology and applied pharmacology. 2019 10; 380(?):114696. doi: 10.1016/j.taap.2019.114696. [PMID: 31381904]
  • Anne Mahringer, Alexandra Bernd, David S Miller, Gert Fricker. Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules. Biological chemistry. 2019 09; 400(10):1335-1345. doi: 10.1515/hsz-2018-0425. [PMID: 30913027]
  • Xin Fu, Zihang Shi, Yun Jiang, Lingling Jiang, Mingfang Qi, Tao Xu, Tianlai Li. A family of auxin conjugate hydrolases from Solanum lycopersicum and analysis of their roles in flower pedicel abscission. BMC plant biology. 2019 Jun; 19(1):233. doi: 10.1186/s12870-019-1840-9. [PMID: 31159738]
  • Sayani Dasgupta, Michael A Fishman, Leandro M Castro, Alexandre K Tashima, Emer S Ferro, Lloyd D Fricker. Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells. Biomolecules. 2019 05; 9(6):. doi: 10.3390/biom9060207. [PMID: 31142026]
  • Peng-Cheng Li, Ke Li, Juan Wang, Chuan-Zhi Zhao, Shu-Zhen Zhao, Lei Hou, Han Xia, Chang-Le Ma, Xing-Jun Wang. The AAA-ATPase MIDASIN 1 Functions in Ribosome Biogenesis and Is Essential for Embryo and Root Development. Plant physiology. 2019 05; 180(1):289-304. doi: 10.1104/pp.18.01225. [PMID: 30755475]
  • A Ya Valiakhmetov, A V Kuchin, N E Suzina, A N Zvonarev, A O Shepelyakovskaya. Glucose causes primary necrosis in exponentially grown yeast Saccharomyces cerevisiae. FEMS yeast research. 2019 05; 19(3):. doi: 10.1093/femsyr/foz019. [PMID: 30785621]
  • Sabrina H Werby, Lynette Cegelski. Spectral comparisons of mammalian cells and intact organelles by solid-state NMR. Journal of structural biology. 2019 04; 206(1):49-54. doi: 10.1016/j.jsb.2018.05.007. [PMID: 29859329]
  • Jinrong Li, Christian H Lemon. Mouse Parabrachial Neurons Signal a Relationship between Bitter Taste and Nociceptive Stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2019 02; 39(9):1631-1648. doi: 10.1523/jneurosci.2000-18.2018. [PMID: 30606758]
  • Shun Zhang, Shu Xiang, Jinji Yang, Jinyue Shi, Xiaomei Guan, Jianrong Jiang, Yingming Wei, Chan Luo, Deshun Shi, Fenghua Lu. Optimization of parthenogenetic activation of rabbit oocytes and development of rabbit embryo by somatic cell nuclear transfer. Reproduction in domestic animals = Zuchthygiene. 2019 Feb; 54(2):258-269. doi: 10.1111/rda.13344. [PMID: 30220080]
  • Alison D Walters, Kwabena Amoateng, Renjie Wang, Jian-Hua Chen, Gerry McDermott, Carolyn A Larabell, Olivier Gadal, Orna Cohen-Fix. Nuclear envelope expansion in budding yeast is independent of cell growth and does not determine nuclear volume. Molecular biology of the cell. 2019 01; 30(1):131-145. doi: 10.1091/mbc.e18-04-0204. [PMID: 30379612]
  • Jing Ying Wang, Zhe Wang, Ming Yue Li, Zhihong Zhang, Chunliu Mi, Hong Xiang Zuo, Yue Xing, Yan-Ling Wu, Li-Hua Lian, Guang Hua Xu, Lian Xun Piao, Juan Ma, Xuejun Jin. Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways. Chemico-biological interactions. 2018 Dec; 296(?):134-144. doi: 10.1016/j.cbi.2018.09.014. [PMID: 30266538]
  • Fang Feng, Lamis Yehia, Ying Ni, Yi Seok Chang, Sissy Meihua Jhiang, Charis Eng. A Nonpump Function of Sodium Iodide Symporter in Thyroid Cancer via Cross-talk with PTEN Signaling. Cancer research. 2018 11; 78(21):6121-6133. doi: 10.1158/0008-5472.can-18-1954. [PMID: 30217930]
  • Umarah Mubeen, Jessica Jüppner, Jessica Alpers, Dirk K Hincha, Patrick Giavalisco. Target of Rapamycin Inhibition in Chlamydomonas reinhardtii Triggers de Novo Amino Acid Synthesis by Enhancing Nitrogen Assimilation. The Plant cell. 2018 10; 30(10):2240-2254. doi: 10.1105/tpc.18.00159. [PMID: 30228127]
  • Andrew Elliott, Sidney L Shaw. A Cycloheximide-Sensitive Step in Transverse Microtubule Array Patterning. Plant physiology. 2018 10; 178(2):684-698. doi: 10.1104/pp.18.00672. [PMID: 30154175]
  • Wei Li, Bi-De Liu, Kai Liao, Yong Liu, Zi-Jin Wan, Yu-Fen Dong, Qian-Qian Cao, Qian Zhu, Xiao Gu. Alteration of Androgen Receptor Protein Stability by Triptolide in LNCaP Cells. Medicina (Kaunas, Lithuania). 2018 May; 54(3):. doi: 10.3390/medicina54030039. [PMID: 30344270]
  • Sheng Liu, Josephine Iaria, Richard J Simpson, Hong-Jian Zhu. Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1. Cell communication and signaling : CCS. 2018 03; 16(1):10. doi: 10.1186/s12964-018-0223-4. [PMID: 29534718]
  • Kazuki Motomura, Tomokazu Kawashima, Frédéric Berger, Tetsu Kinoshita, Tetsuya Higashiyama, Daisuke Maruyama. A pharmacological study of Arabidopsis cell fusion between the persistent synergid and endosperm. Journal of cell science. 2018 01; 131(2):. doi: 10.1242/jcs.204123. [PMID: 28808086]
  • Clemens Malainer, Daniel Schachner, Enrico Sangiovanni, Atanas G Atanasov, Stefan Schwaiger, Hermann Stuppner, Elke H Heiss, Verena M Dirsch. Eurycomalactone Inhibits Expression of Endothelial Adhesion Molecules at a Post-Transcriptional Level. Journal of natural products. 2017 12; 80(12):3186-3193. doi: 10.1021/acs.jnatprod.7b00503. [PMID: 29148754]
  • Yongchang Lai, Liang Tao, Yifan Zhao, Xiaomin Zhang, Xingjuan Sun, Qin Wang, Chengfang Xu. Cx32 inhibits TNFα-induced extrinsic apoptosis with and without EGFR suppression. Oncology reports. 2017 Nov; 38(5):2885-2892. doi: 10.3892/or.2017.5950. [PMID: 28901517]
  • Elina Karhu, Janne Isojärvi, Pia Vuorela, Leena Hanski, Adyary Fallarero. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. Journal of natural products. 2017 10; 80(10):2602-2608. doi: 10.1021/acs.jnatprod.6b01052. [PMID: 29043803]
  • Rik Mencke, Geert Harms, Jill Moser, Matijs van Meurs, Arjan Diepstra, Henri G Leuvenink, Jan-Luuk Hillebrands. Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease. JCI insight. 2017 10; 2(20):. doi: 10.1172/jci.insight.94375. [PMID: 29046474]
  • Hongsheng Wang, Wen Li, Jing Xu, Tao Zhang, Dongqing Zuo, Zifei Zhou, Binhui Lin, Gangyang Wang, Zhuoying Wang, Wei Sun, Mengxiong Sun, Shimin Chang, Zhengdong Cai, Yingqi Hua. NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy. Cell death & disease. 2017 09; 8(9):e3048. doi: 10.1038/cddis.2017.438. [PMID: 28906492]
  • Bindu Prasuna Aloor, Uday Kiran Avasthi, Agepati S Raghavendra. Stimulation by abscisic acid of the activity of phosphoenolpyruvate carboxylase in leaf disks of Amaranthus hypochondriacus L., C4 plant: role of pH and protein levels. Protoplasma. 2017 Sep; 254(5):1973-1981. doi: 10.1007/s00709-017-1091-2. [PMID: 28251362]
  • Lisa Maria Mustachio, Yun Lu, Laura J Tafe, Vincent Memoli, Jaime Rodriguez-Canales, Barbara Mino, Pamela Andrea Villalobos, Ignacio Wistuba, Hiroyuki Katayama, Samir M Hanash, Jason Roszik, Masanori Kawakami, Kwang-Jin Cho, John F Hancock, Fadzai Chinyengetere, Shanhu Hu, Xi Liu, Sarah J Freemantle, Ethan Dmitrovsky. Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer. Molecular cancer research : MCR. 2017 07; 15(7):905-914. doi: 10.1158/1541-7786.mcr-16-0369. [PMID: 28242811]
  • Juan Moral, Gracia Montilla-Bascón, Francisco J Canales, Diego Rubiales, Elena Prats. Cytoskeleton reorganization/disorganization is a key feature of induced inaccessibility for defence to successive pathogen attacks. Molecular plant pathology. 2017 Jun; 18(5):662-671. doi: 10.1111/mpp.12424. [PMID: 27147535]
  • Hong Zhang, Ke-Xin Zhou, Wei-Qing Wang, Shu-Jun Liu, Song-Quan Song. Proteome analysis reveals an energy-dependent central process for Populus×canadensis seed germination. Journal of plant physiology. 2017 Jun; 213(?):134-147. doi: 10.1016/j.jplph.2017.03.008. [PMID: 28384531]
  • Sara R Noumeur, Soleiman E Helaly, Rolf Jansen, Marcus Gereke, Theresia E B Stradal, Daoud Harzallah, Marc Stadler. Preussilides A-F, Bicyclic Polyketides from the Endophytic Fungus Preussia similis with Antiproliferative Activity. Journal of natural products. 2017 05; 80(5):1531-1540. doi: 10.1021/acs.jnatprod.7b00064. [PMID: 28398049]
  • Po-Hao Hsu, Yu-Ting Ma, Ya-Ching Fang, Jing-Jia Huang, Yu-Ling Gan, Pei-Tzu Chang, Guey-Mei Jow, Chih-Yung Tang, Chung-Jiuan Jeng. Cullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels. Scientific reports. 2017 01; 7(?):40825. doi: 10.1038/srep40825. [PMID: 28098200]
  • Yu Luo, Eugenia Russinova. Quantitative Microscopic Analysis of Plasma Membrane Receptor Dynamics in Living Plant Cells. Methods in molecular biology (Clifton, N.J.). 2017; 1564(?):121-132. doi: 10.1007/978-1-4939-6813-8_10. [PMID: 28124250]
  • Mariangela Centrone, Marianna Ranieri, Annarita Di Mise, Sante Princiero Berlingerio, Annamaria Russo, Peter M T Deen, Olivier Staub, Giovanna Valenti, Grazia Tamma. AQP2 Abundance is Regulated by the E3-Ligase CHIP Via HSP70. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2017; 44(2):515-531. doi: 10.1159/000485088. [PMID: 29145196]
  • Yoriko Sakane, Naotetsu Kanamoto, Ichiro Yamauchi, Tetsuya Tagami, Yusuke Morita, Masako Miura, Masakatsu Sone, Akihiro Yasoda, Takeshi Kimura, Kazuwa Nakao, Nobuya Inagaki. Regulation of type 1 iodothyronine deiodinase by LXRα. PloS one. 2017; 12(6):e0179213. doi: 10.1371/journal.pone.0179213. [PMID: 28617824]
  • Dapeng Jin, Yong-Guo Zhang, Shaoping Wu, Rong Lu, Zhijie Lin, Yuanyuan Zheng, Honglei Chen, Gabriella Cs-Szabo, Jun Sun. Vitamin D receptor is a novel transcriptional regulator for Axin1. The Journal of steroid biochemistry and molecular biology. 2017 01; 165(Pt B):430-437. doi: 10.1016/j.jsbmb.2016.09.002. [PMID: 27601169]
  • Petra Bonova, Miroslava Nemethova, Milina Matiasova, Martin Bona, Miroslav Gottlieb. Blood cells serve as a source of factor-inducing rapid ischemic tolerance in brain. The European journal of neuroscience. 2016 12; 44(11):2958-2965. doi: 10.1111/ejn.13422. [PMID: 27706857]
  • Rachel E Webster, Wanda M Waterworth, Wolfgang Stuppy, Christopher E West, Roland Ennos, Clifford M Bray, Hugh W Pritchard. Biomechanical, biochemical, and morphological mechanisms of heat shock-mediated germination in Carica papaya seed. Journal of experimental botany. 2016 12; 67(22):6373-6384. doi: 10.1093/jxb/erw402. [PMID: 27811004]
  • Natalia I Agalakova, Irina V Brailovskaya, Svetlana A Konovalova, Sergei M Korotkov, Elena A Lavrova, Anatolii A Nikiforov. ATP-consuming processes in hepatocytes of river lamprey Lampetra fluviatilis on the course of prespawning starvation. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2016 11; 201(?):95-100. doi: 10.1016/j.cbpa.2016.07.002. [PMID: 27399971]
  • Lawrence C Blume, Sandra Leone-Kabler, Deborah J Luessen, Glen S Marrs, Erica Lyons, Caroline E Bass, Rong Chen, Dana E Selley, Allyn C Howlett. Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner. Journal of neurochemistry. 2016 11; 139(3):396-407. doi: 10.1111/jnc.13767. [PMID: 27513693]
  • Chuan-Xi Wang, Rong Ding, Shu-Tai Jiang, Jin-Shan Tang, Dan Hu, Guo-Dong Chen, Feng Lin, Kui Hong, Xin-Sheng Yao, Hao Gao. Aldgamycins J-O, 16-Membered Macrolides with a Branched Octose Unit from Streptomycetes sp. and Their Antibacterial Activities. Journal of natural products. 2016 10; 79(10):2446-2454. doi: 10.1021/acs.jnatprod.6b00200. [PMID: 27690254]
  • Zukaa Al Taleb, Andreas Petry, Tabughang Franklin Chi, Daniela Mennerich, Agnes Görlach, Elitsa Y Dimova, Thomas Kietzmann. Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2. Journal of molecular medicine (Berlin, Germany). 2016 10; 94(10):1153-1166. doi: 10.1007/s00109-016-1439-7. [PMID: 27286880]
  • P Wanjugi, G A Fox, V J Harwood. The Interplay Between Predation, Competition, and Nutrient Levels Influences the Survival of Escherichia coli in Aquatic Environments. Microbial ecology. 2016 10; 72(3):526-37. doi: 10.1007/s00248-016-0825-6. [PMID: 27484343]
  • Xiang Yu, Matthew R Willmann, Stephen J Anderson, Brian D Gregory. Genome-Wide Mapping of Uncapped and Cleaved Transcripts Reveals a Role for the Nuclear mRNA Cap-Binding Complex in Cotranslational RNA Decay in Arabidopsis. The Plant cell. 2016 10; 28(10):2385-2397. doi: 10.1105/tpc.16.00456. [PMID: 27758893]
  • Yongliang Shang, Hongna Wang, Pengfei Jia, Haichao Zhao, Chao Liu, Weixiao Liu, Zhenhua Song, Zhiliang Xu, Lin Yang, Yanfang Wang, Wei Li. Autophagy regulates spermatid differentiation via degradation of PDLIM1. Autophagy. 2016 09; 12(9):1575-92. doi: 10.1080/15548627.2016.1192750. [PMID: 27310465]
  • H Chung, A Vilaysane, A Lau, M Stahl, V Morampudi, A Bondzi-Simpson, J M Platnich, N A Bracey, M-C French, P L Beck, J Chun, B A Vallance, D A Muruve. NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis. Cell death and differentiation. 2016 08; 23(8):1331-46. doi: 10.1038/cdd.2016.14. [PMID: 26891693]
  • Ana Paola G Lombardi, Raisa Pisolato, Carolina M Vicente, Maria Fatima M Lazari, Thaís F G Lucas, Catarina S Porto. Estrogen receptor beta (ERβ) mediates expression of β-catenin and proliferation in prostate cancer cell line PC-3. Molecular and cellular endocrinology. 2016 07; 430(?):12-24. doi: 10.1016/j.mce.2016.04.012. [PMID: 27107935]
  • Tomoki Nishioka, Mohsen Mohamed Elsharkawy, Haruhisa Suga, Koji Kageyama, Mitsuro Hyakumachi, Masafumi Shimizu. Development of Culture Medium for the Isolation of Flavobacterium and Chryseobacterium from Rhizosphere Soil. Microbes and environments. 2016 Jun; 31(2):104-10. doi: 10.1264/jsme2.me15144. [PMID: 27098502]
  • Shu-Jun Liu, Heng-Heng Xu, Wei-Qing Wang, Ni Li, Wei-Ping Wang, Zhuang Lu, Ian Max Møller, Song-Quan Song. Identification of embryo proteins associated with seed germination and seedling establishment in germinating rice seeds. Journal of plant physiology. 2016 Jun; 196-197(?):79-92. doi: 10.1016/j.jplph.2016.02.021. [PMID: 27085178]
  • Ivana Vidlickova, Franck Dequiedt, Lenka Jelenska, Olga Sedlakova, Michal Pastorek, Stanislav Stuchlik, Jaromir Pastorek, Miriam Zatovicova, Silvia Pastorekova. Apoptosis-induced ectodomain shedding of hypoxia-regulated carbonic anhydrase IX from tumor cells: a double-edged response to chemotherapy. BMC cancer. 2016 Mar; 16(?):239. doi: 10.1186/s12885-016-2267-4. [PMID: 26993100]
  • Peng Cui, Tao Chen, Tao Qin, Feng Ding, Zhenyu Wang, Hao Chen, Liming Xiong. The RNA Polymerase II C-Terminal Domain Phosphatase-Like Protein FIERY2/CPL1 Interacts with eIF4AIII and Is Essential for Nonsense-Mediated mRNA Decay in Arabidopsis. The Plant cell. 2016 Mar; 28(3):770-85. doi: 10.1105/tpc.15.00771. [PMID: 26887918]
  • Yaroslav Bobak, Yuliya Kurlishchuk, Bozhena Vynnytska-Myronovska, Olesia Grydzuk, Galyna Shuvayeva, Maria J Redowicz, Leoni A Kunz-Schughart, Oleh Stasyk. Arginine deprivation induces endoplasmic reticulum stress in human solid cancer cells. The international journal of biochemistry & cell biology. 2016 Jan; 70(?):29-38. doi: 10.1016/j.biocel.2015.10.027. [PMID: 26546743]
  • Wei Fan, He Qiang Lou, Yu Long Gong, Mei Ya Liu, Meng Jie Cao, Yu Liu, Jian Li Yang, Shao Jian Zheng. Characterization of an inducible C2 H2 -type zinc finger transcription factor VuSTOP1 in rice bean (Vigna umbellata) reveals differential regulation between low pH and aluminum tolerance mechanisms. The New phytologist. 2015 Oct; 208(2):456-68. doi: 10.1111/nph.13456. [PMID: 25970766]
  • Min-Young Kwon, Eunhee Park, Seon-Jin Lee, Su Wol Chung. Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death. Oncotarget. 2015 Sep; 6(27):24393-403. doi: 10.18632/oncotarget.5162. [PMID: 26405158]
  • Min Peng, Julian Ostrovsky, Young Joon Kwon, Erzsebet Polyak, Joseph Licata, Mai Tsukikawa, Eric Marty, Jeffrey Thomas, Carolyn A Felix, Rui Xiao, Zhe Zhang, David L Gasser, Yair Argon, Marni J Falk. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Human molecular genetics. 2015 Sep; 24(17):4829-47. doi: 10.1093/hmg/ddv207. [PMID: 26041819]
  • Jeffery Chen, Jun Guo, Tonghua Yang, Wentao Li, Shawn M Lamothe, Yudi Kang, John A Szendrey, Shetuan Zhang. Rab11-dependent Recycling of the Human Ether-a-go-go-related Gene (hERG) Channel. The Journal of biological chemistry. 2015 Aug; 290(34):21101-21113. doi: 10.1074/jbc.m115.636324. [PMID: 26152716]
  • Jinhua Chen, Liqiong Gao, Dongwon Baek, Chunlin Liu, Ying Ruan, Huazhong Shi. Detoxification function of the Arabidopsis sulphotransferase AtSOT12 by sulphonation of xenobiotics. Plant, cell & environment. 2015 Aug; 38(8):1673-82. doi: 10.1111/pce.12525. [PMID: 25736839]
  • Michael A Eskander, Shivani Ruparel, Dustin P Green, Paul B Chen, Elaine D Por, Nathaniel A Jeske, Xiaoli Gao, Eric R Flores, Kenneth M Hargreaves. Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 Jun; 35(22):8593-603. doi: 10.1523/jneurosci.3993-14.2015. [PMID: 26041925]
  • Marcos V N Capone, Miriam F Suzuki, João E Oliveira, Renata Damiani, Carlos R J Soares, Paolo Bartolini. N-glycoprofiling analysis in a simple glycoprotein model: a comparison between recombinant and pituitary glycosylated human prolactin. Journal of biotechnology. 2015 May; 202(?):78-87. doi: 10.1016/j.jbiotec.2014.11.034. [PMID: 25499076]
  • Jibiao Li, David J Matye, Tiangang Li. Insulin resistance induces posttranslational hepatic sortilin 1 degradation in mice. The Journal of biological chemistry. 2015 May; 290(18):11526-36. doi: 10.1074/jbc.m115.641225. [PMID: 25805502]
  • Stephan Philipp, Justyna Sosna, Johannes Plenge, Holger Kalthoff, Dieter Adam. Homoharringtonine, a clinically approved anti-leukemia drug, sensitizes tumor cells for TRAIL-induced necroptosis. Cell communication and signaling : CCS. 2015 Apr; 13(?):25. doi: 10.1186/s12964-015-0103-0. [PMID: 25925126]
  • Shuhui Wang, Peggy Robinet, Jonathan D Smith, Kailash Gulshan. ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy. Proceedings of the National Academy of Sciences of the United States of America. 2015 Mar; 112(12):3728-33. doi: 10.1073/pnas.1422455112. [PMID: 25775599]
  • Mary S Matsui, Michael J Petris, Yoko Niki, Nevena Karaman-Jurukovska, Neelam Muizzuddin, Masamitsu Ichihashi, Daniel B Yarosh. Omeprazole, a gastric proton pump inhibitor, inhibits melanogenesis by blocking ATP7A trafficking. The Journal of investigative dermatology. 2015 Mar; 135(3):834-841. doi: 10.1038/jid.2014.461. [PMID: 25337692]
  • Ranamalie Amarasinghe, Jacqueline Poldy, Yuki Matsuba, Russell A Barrow, Jan M Hemmi, Eran Pichersky, Rod Peakall. UV-B light contributes directly to the synthesis of chiloglottone floral volatiles. Annals of botany. 2015 Mar; 115(4):693-703. doi: 10.1093/aob/mcu262. [PMID: 25649114]
  • Rangel L Silva, Alexandre H Lopes, Rafael O França, Sílvio M Vieira, Ellen C C Silva, Rodrigo C N Amorim, Fernando Q Cunha, Adrian M Pohlit, Thiago M Cunha. The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation. Journal of natural products. 2015 Feb; 78(2):241-9. doi: 10.1021/np500796f. [PMID: 25667960]
  • Min Ae Han, Seon Min Woo, Kyoung-jin Min, Shin Kim, Jong-Wook Park, Dong Eun Kim, Sang Hyun Kim, Yung Hyun Choi, Taeg Kyu Kwon. 6-Shogaol enhances renal carcinoma Caki cells to TRAIL-induced apoptosis through reactive oxygen species-mediated cytochrome c release and down-regulation of c-FLIP(L) expression. Chemico-biological interactions. 2015 Feb; 228(?):69-78. doi: 10.1016/j.cbi.2015.01.020. [PMID: 25619640]
  • Kyosuke Mukae, Yuko Inoue, Yuji Moriyasu. ATG5-knockout mutants of Physcomitrella provide a platform for analyzing the involvement of autophagy in senescence processes in plant cells. Plant signaling & behavior. 2015; 10(11):e1086859. doi: 10.1080/15592324.2015.1086859. [PMID: 26368055]
  • A M Egorova, I A Tarchevsky. Antipathogenic phenomenon of cycloheximide. Doklady. Biochemistry and biophysics. 2015; 461(?):98-101. doi: 10.1134/s160767291502009x. [PMID: 25937224]
  • Lung-Yuan Wu, Wang-Chuan Chen, Fan-Shiu Tsai, Chin-Chuan Tsai, Chi-Rei Wu, Li-Wei Lin. p-Hydroxybenzyl Alcohol, an Active Phenolic Ingredient of Gastrodia elata, Reverses the Cycloheximide-Induced Memory Deficit by Activating the Adrenal Gland in Rats. The American journal of Chinese medicine. 2015; 43(8):1593-604. doi: 10.1142/s0192415x15500901. [PMID: 26621444]
  • Toshiaki Tanaka, Mitsuyoshi Iino, Kaoru Goto. Knockdown of Sec8 enhances the binding affinity of c-Jun N-terminal kinase (JNK)-interacting protein 4 for mitogen-activated protein kinase kinase 4 (MKK4) and suppresses the phosphorylation of MKK4, p38, and JNK, thereby inhibiting apoptosis. The FEBS journal. 2014 Dec; 281(23):5237-50. doi: 10.1111/febs.13063. [PMID: 25244576]
  • Ena Music, Saad Khan, Imran Khamis, John J Heikkila. Accumulation of heme oxygenase-1 (HSP32) in Xenopus laevis A6 kidney epithelial cells treated with sodium arsenite, cadmium chloride or proteasomal inhibitors. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2014 Nov; 166(?):75-87. doi: 10.1016/j.cbpc.2014.07.007. [PMID: 25064141]
  • Christian Meesters, Timon Mönig, Julian Oeljeklaus, Daniel Krahn, Corey S Westfall, Bettina Hause, Joseph M Jez, Markus Kaiser, Erich Kombrink. A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana. Nature chemical biology. 2014 Oct; 10(10):830-6. doi: 10.1038/nchembio.1591. [PMID: 25129030]