Pyridoxal (BioDeep_00000001417)

 

Secondary id: BioDeep_00000398746, BioDeep_00000400289

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite


代谢物信息卡片


3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde

化学式: C8H9NO3 (167.0582404)
中文名称: 吡哆醛
谱图信息: 最多检出来源 Homo sapiens(blood) 0.02%

Reviewed

Last reviewed on 2024-07-02.

Cite this Page

Pyridoxal. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/pyridoxal (retrieved 2024-09-17) (BioDeep RN: BioDeep_00000001417). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC1=NC=C(C(=C1O)C=O)CO
InChI: InChI=1/C8H9NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,4,10,12H,3H2,1H3

描述信息

Pyridoxal is a pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. Pyridoxal, also known as pyridoxaldehyde, belongs to the class of organic compounds known as pyridoxals and derivatives. Pyridoxals and derivatives are compounds containing a pyridoxal moiety, which consists of a pyridine ring substituted at positions 2, 3, 4, and 5 by a methyl group, a hydroxyl group, a carbaldehyde group, and a hydroxymethyl group, respectively. Pyridoxal is one form of vitamin B6. Pyridoxal exists in all living species, ranging from bacteria to humans. In humans, pyridoxal is involved in glycine and serine metabolism. Pyridoxal has been detected, but not quantified in several different foods, such as sourdoughs, lichee, arctic blackberries, watercress, and cottonseeds. Some medically relevant bacteria, such as those in the genera Granulicatella and Abiotrophia, require pyridoxal for growth. This nutritional requirement can lead to the culture phenomenon of satellite growth. In in vitro culture, these pyridoxal-dependent bacteria may only grow in areas surrounding colonies of bacteria from other genera ("satellitism") that are capable of producing pyridoxal. Pridoxal has a role as a cofactor, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite.

同义名列表

9 个代谢物同义名

3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde; 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde; 3-HYDROXY-5-(hydroxymethyl)-2-methylisonicotinaldehyde; Pyridoxal hydrochrolide; Pyridoxal (Vitamin B6); Pyridoxaldehyde; Isopyridoxal; pyridoxal; Pyridoxal (VB6)



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(5)

PlantCyc(0)

代谢反应

515 个相关的代谢反应过程信息。

Reactome(72)

BioCyc(24)

WikiPathways(0)

Plant Reactome(279)

INOH(1)

PlantCyc(128)

COVID-19 Disease Map(0)

PathBank(11)

  • Vitamin B6 Metabolism: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Hypophosphatasia: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Vitamin B6 Metabolism: Oxygen + Pyridoxamine 5'-phosphate + Water ⟶ Ammonia + Hydrogen peroxide + Pyridoxal 5'-phosphate
  • Vitamin B6 Metabolism: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Hypophosphatasia: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Vitamin B6 Metabolism: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Vitamin B6 Metabolism: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Vitamin B6 Metabolism: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Vitamin B6 Metabolism: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Hypophosphatasia: 4-Pyridoxic acid ⟶ 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate
  • Vitamin B6: 2-Oxo-3-hydroxy-4-phosphobutanoic acid + L-Glutamic acid ⟶ O-Phospho-4-hydroxy-L-threonine + Oxoglutaric acid

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jia-Jin Wu, Senlin Zhu, Yi-Fan Tang, Fengfei Gu, Jian-Xin Liu, Hui-Zeng Sun. Microbiota-host crosstalk in the newborn and adult rumen at single-cell resolution. BMC biology. 2022 12; 20(1):280. doi: 10.1186/s12915-022-01490-1. [PMID: 36514051]
  • Francisco Mainardi Martins, Josiéli Demetrio Siqueira, Bernardo Almeida Iglesias, Otávio Augusto Chaves, Davi Fernando Back. Pyridoxal water-soluble cobalt(II) helicates: Synthesis, structural analysis, and interactions with biomacromolecules. Journal of inorganic biochemistry. 2022 08; 233(?):111854. doi: 10.1016/j.jinorgbio.2022.111854. [PMID: 35636301]
  • Zhibin Cao, Huiwu Tang, Yaohui Cai, Bohong Zeng, Jialiang Zhao, Xiuying Tang, Ming Lu, Huimin Wang, Xuejing Zhu, Xiaofeng Wu, Linfeng Yuan, Jianlin Wan. Natural variation of HTH5 from wild rice, Oryza rufipogon Griff., is involved in conferring high-temperature tolerance at the heading stage. Plant biotechnology journal. 2022 08; 20(8):1591-1605. doi: 10.1111/pbi.13835. [PMID: 35514030]
  • Lei Xu, Yu-Jing Fang, Meng-Meng Che, Alinuer Abulimiti, Chu-Yi Huang, Cai-Xia Zhang. Association of Serum Pyridoxal-5'-Phosphate, Pyridoxal, and PAr with Colorectal Cancer Risk: A Large-Scale Case-Control Study. Nutrients. 2022 Jun; 14(12):. doi: 10.3390/nu14122389. [PMID: 35745119]
  • Yuying Yuan, Jinqiu Yu, Lingzelai Kong, Wenkai Zhang, Xiangyin Hou, Guowen Cui. Genome-wide investigation of the PLD gene family in alfalfa (Medicago sativa L.): identification, analysis and expression. BMC genomics. 2022 Mar; 23(1):243. doi: 10.1186/s12864-022-08424-9. [PMID: 35350974]
  • Yih-Jeng Tsai, Ming-Chieh Ma, Pi-Hui Wu, Wen-Bin Wu. Novel involvement of PLD-PKCδ-CREB axis in regulating FGF-2-mediated pentraxin 3 production in human nasal fibroblast cells. Journal of cellular physiology. 2022 03; 237(3):1871-1887. doi: 10.1002/jcp.30657. [PMID: 34897684]
  • Masashi Harada, Kazutaka Shimbo, Sachise Karakawa. Preparation of racemic α-amino acid standards for accurate mass spectrometric analysis via racemization catalyzed by a hydrophobic pyridoxal derivative. Talanta. 2021 Nov; 234(?):122661. doi: 10.1016/j.talanta.2021.122661. [PMID: 34364469]
  • Michael P Whyte, Jennifer D May, William H McAlister, Katherine Burgener, Samuel R Cortez, Raymond Kreienkamp, Olivia Castro, Rachel Verzola, Ana Solis Zavala, Christopher C McPherson, Gary S Gottesman, Karen L Ericson, Stephen P Coburn, Ana Maria Arbelaez. Vitamin B6 deficiency with normal plasma levels of pyridoxal 5'-phosphate in perinatal hypophosphatasia. Bone. 2021 09; 150(?):116007. doi: 10.1016/j.bone.2021.116007. [PMID: 34000433]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Francisco Mainardi Martins, Otávio Augusto Chaves, Thiago V Acunha, Daiane Roman, Bernardo Almeida Iglesias, Davi Fernando Back. Helical water-soluble NiII complexes with pyridoxal ligand derivatives: Structural evaluation and interaction with biomacromolecules. Journal of inorganic biochemistry. 2021 02; 215(?):111307. doi: 10.1016/j.jinorgbio.2020.111307. [PMID: 33341589]
  • Hengli Zhang, Min Wen, Jiayu Chen, Chaojie Yao, Xiao Lin, Zhongxiao Lin, Junnan Ru, Qichuan Zhuge, Su Yang. Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice. BioMed research international. 2021; 2021(?):9916328. doi: 10.1155/2021/9916328. [PMID: 34541001]
  • Juliana A Donohue, Noel W Solomons, Daniela Hampel, Setareh Shahab-Ferdows, Mónica N Orozco, Lindsay H Allen. Micronutrient supplementation of lactating Guatemalan women acutely increases infants' intake of riboflavin, thiamin, pyridoxal, and cobalamin, but not niacin, in a randomized crossover trial. The American journal of clinical nutrition. 2020 09; 112(3):669-682. doi: 10.1093/ajcn/nqaa147. [PMID: 32649760]
  • Ghada Rashad Ibrahim, Iltaf Shah, Salah Gariballa, Javed Yasin, James Barker, Syed Salman Ashraf. Significantly Elevated Levels of Plasma Nicotinamide, Pyridoxal, and Pyridoxamine Phosphate Levels in Obese Emirati Population: A Cross-Sectional Study. Molecules (Basel, Switzerland). 2020 Aug; 25(17):. doi: 10.3390/molecules25173932. [PMID: 32872122]
  • Martina Šrajer Gajdošik, Uroš Andjelković, Dajana Gašo-Sokač, Hrvoje Pavlović, Olga Shevchuk, Tamara Martinović, James Clifton, Marija Begić, Djuro Josić. Proteomic analysis of pyridoxal oxime derivatives treated Listeria monocytogenes reveals down-regulation of the main virulence factor, Listeriolysin O. Food research international (Ottawa, Ont.). 2020 05; 131(?):108951. doi: 10.1016/j.foodres.2019.108951. [PMID: 32247447]
  • Akram A Da'dara, Manal Elzoheiry, Samar N El-Beshbishi, Patrick J Skelly. Vitamin B6 Acquisition and Metabolism in Schistosoma mansoni. Frontiers in immunology. 2020; 11(?):622162. doi: 10.3389/fimmu.2020.622162. [PMID: 33613557]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Christopher Trent Brewer, Lei Yang, Anne Edwards, Yan Lu, Jonathan Low, Jing Wu, Richard E Lee, Taosheng Chen. The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis. Toxicological sciences : an official journal of the Society of Toxicology. 2019 03; 168(1):209-224. doi: 10.1093/toxsci/kfy294. [PMID: 30517741]
  • Tomoyuki Akiyama, Takuo Kubota, Keiichi Ozono, Toshimi Michigami, Daisuke Kobayashi, Shinji Takeyari, Yuichiro Sugiyama, Masahiro Noda, Daisuke Harada, Noriyuki Namba, Atsushi Suzuki, Maiko Utoyama, Sachiko Kitanaka, Mitsugu Uematsu, Yusuke Mitani, Kunihiro Matsunami, Shigeru Takishima, Erika Ogawa, Katsuhiro Kobayashi. Pyridoxal 5'-phosphate and related metabolites in hypophosphatasia: Effects of enzyme replacement therapy. Molecular genetics and metabolism. 2018 09; 125(1-2):174-180. doi: 10.1016/j.ymgme.2018.07.006. [PMID: 30049651]
  • Yukiko Tomioka, Shusuke Numata, Makoto Kinoshita, Hidehiro Umehara, Shin-Ya Watanabe, Masahito Nakataki, Yoshimi Iwayama, Tomoko Toyota, Masashi Ikeda, Hidenaga Yamamori, Shinji Shimodera, Atsushi Tajima, Ryota Hashimoto, Nakao Iwata, Takeo Yoshikawa, Tetsuro Ohmori. Decreased serum pyridoxal levels in schizophrenia: meta-analysis and Mendelian randomization analysis. Journal of psychiatry & neuroscience : JPN. 2018 05; 43(3):194-200. doi: . [PMID: 29688875]
  • Hui Zuo, Grethe S Tell, Per M Ueland, Ottar Nygård, Stein E Vollset, Øivind Midttun, Klaus Meyer, Arve Ulvik. The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK). The American journal of clinical nutrition. 2018 01; 107(1):105-112. doi: 10.1093/ajcn/nqx012. [PMID: 29381795]
  • Tomoyuki Akiyama, Yumiko Hayashi, Yoshiyuki Hanaoka, Takashi Shibata, Mari Akiyama, Hiroki Tsuchiya, Tokito Yamaguchi, Katsuhiro Kobayashi. Pyridoxal 5'-phosphate, pyridoxal, and 4-pyridoxic acid in the paired serum and cerebrospinal fluid of children. Clinica chimica acta; international journal of clinical chemistry. 2017 Sep; 472(?):118-122. doi: 10.1016/j.cca.2017.07.032. [PMID: 28778380]
  • D W Sullivan, R C Peterson, C V Mujer, S C Gad. A 7-day intravenous toxicity study and neurotoxicity assessment of pyridorin in Sprague-Dawley rats. Human & experimental toxicology. 2017 Jul; 36(7):718-726. doi: 10.1177/0960327116661023. [PMID: 27507076]
  • Shilpa Bothra, Yachana Upadhyay, Rajender Kumar, S K Ashok Kumar, Suban K Sahoo. Chemically modified cellulose strips with pyridoxal conjugated red fluorescent gold nanoclusters for nanomolar detection of mercuric ions. Biosensors & bioelectronics. 2017 Apr; 90(?):329-335. doi: 10.1016/j.bios.2016.11.066. [PMID: 27940235]
  • Björn Gylling, Robin Myte, Jörn Schneede, Göran Hallmans, Jenny Häggström, Ingegerd Johansson, Arve Ulvik, Per M Ueland, Bethany Van Guelpen, Richard Palmqvist. Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status. The American journal of clinical nutrition. 2017 04; 105(4):897-904. doi: 10.3945/ajcn.116.139337. [PMID: 28275126]
  • Joyce Y Huang, Lesley M Butler, Øivind Midttun, Woon-Puay Koh, Per M Ueland, Renwei Wang, Aizhen Jin, Yu-Tang Gao, Jian-Min Yuan. Serum B6 vitamers (pyridoxal 5'-phosphate, pyridoxal, and 4-pyridoxic acid) and pancreatic cancer risk: two nested case-control studies in Asian populations. Cancer causes & control : CCC. 2016 Dec; 27(12):1447-1456. doi: 10.1007/s10552-016-0822-6. [PMID: 27830400]
  • Valentina Bušić, Maja Katalinić, Goran Šinko, Zrinka Kovarik, Dajana Gašo-Sokač. Pyridoxal oxime derivative potency to reactivate cholinesterases inhibited by organophosphorus compounds. Toxicology letters. 2016 Nov; 262(?):114-122. doi: 10.1016/j.toxlet.2016.09.015. [PMID: 27693733]
  • Déborah Mathis, Lucia Abela, Monique Albersen, Céline Bürer, Lisa Crowther, Karin Beese, Hans Hartmann, Levinus A Bok, Eduard Struys, Sorina M Papuc, Anita Rauch, Martin Hersberger, Nanda M Verhoeven-Duif, Barbara Plecko. The value of plasma vitamin B6 profiles in early onset epileptic encephalopathies. Journal of inherited metabolic disease. 2016 09; 39(5):733-741. doi: 10.1007/s10545-016-9955-8. [PMID: 27342130]
  • Arve Ulvik, Eva R Pedersen, Gard Ft Svingen, Adrian McCann, Øivind Midttun, Ottar Nygård, Per M Ueland. Vitamin B-6 catabolism and long-term mortality risk in patients with coronary artery disease. The American journal of clinical nutrition. 2016 06; 103(6):1417-25. doi: 10.3945/ajcn.115.126342. [PMID: 27169836]
  • Vegard Lysne, Elin Strand, Gard F T Svingen, Bodil Bjørndal, Eva R Pedersen, Øivind Midttun, Thomas Olsen, Per M Ueland, Rolf K Berge, Ottar Nygård. Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats. Nutrients. 2016 Jan; 8(1):. doi: 10.3390/nu8010026. [PMID: 26742069]
  • Tonje Holte Stea, Solvor B Stølevik, Sveinung Berntsen, Nasser Ezzathkah Bastani, Gøran Paulsen, Hilde Lohne Seiler, Ken J Hetlelid, Rune Blomhoff, Mohammad Azam Mansoor. Effect of Omega-3 and Vitamins E + C Supplements on the Concentration of Serum B-Vitamins and Plasma Redox Aminothiol Antioxidant Status in Elderly Men after Strength Training for Three Months. Annals of nutrition & metabolism. 2016; 68(2):145-55. doi: 10.1159/000443847. [PMID: 26848570]
  • Elisa Oppici, Sonia Fargue, Emma S Reid, Philippa B Mills, Peter T Clayton, Christopher J Danpure, Barbara Cellini. Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I. Human molecular genetics. 2015 Oct; 24(19):5500-11. doi: 10.1093/hmg/ddv276. [PMID: 26199318]
  • Daisuke Kobayashi, Teruki Yoshimura, Atsushi Johno, Mika Ishikawa, Keiko Sasaki, Keiji Wada. Decrease in pyridoxal-5'-phosphate concentration and increase in pyridoxal concentration in rat plasma by 4'-O-methylpyridoxine administration. Nutrition research (New York, N.Y.). 2015 Jul; 35(7):637-42. doi: 10.1016/j.nutres.2015.05.015. [PMID: 26092494]
  • Tonia C Carter, Faith Pangilinan, Anne M Molloy, Ruzong Fan, Yifan Wang, Barry Shane, Eileen R Gibney, Øivind Midttun, Per M Ueland, Cheryl D Cropp, Yoonhee Kim, Alexander F Wilson, Joan E Bailey-Wilson, Lawrence C Brody, James L Mills. Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults. The Journal of nutrition. 2015 Jul; 145(7):1386-93. doi: 10.3945/jn.114.208769. [PMID: 25972531]
  • Monique Albersen, Marjolein Bosma, Judith J M Jans, Floris C Hofstede, Peter M van Hasselt, Monique G M de Sain-van der Velden, Gepke Visser, Nanda M Verhoeven-Duif. Vitamin B6 in plasma and cerebrospinal fluid of children. PloS one. 2015; 10(3):e0120972. doi: 10.1371/journal.pone.0120972. [PMID: 25760040]
  • Per Magne Ueland, Arve Ulvik, Luisa Rios-Avila, Øivind Midttun, Jesse F Gregory. Direct and Functional Biomarkers of Vitamin B6 Status. Annual review of nutrition. 2015; 35(?):33-70. doi: 10.1146/annurev-nutr-071714-034330. [PMID: 25974692]
  • ShuoHao Huang, JianYun Zhang, Zhen Tao, Liang Lei, YongHui Yu, LongQuan Huang. Enzymatic conversion from pyridoxal to pyridoxine caused by microorganisms within tobacco phyllosphere. Plant physiology and biochemistry : PPB. 2014 Dec; 85(?):9-13. doi: 10.1016/j.plaphy.2014.10.006. [PMID: 25394795]
  • Ilan Matok, Shannon Clark, Steve Caritis, Menachem Miodovnik, Jason G Umans, Gary Hankins, Donald R Mattison, Gideon Koren. Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs. Journal of clinical pharmacology. 2014 Dec; 54(12):1429-33. doi: 10.1002/jcph.369. [PMID: 25052410]
  • Narimasa Katsuta, Tohru Ohnuma, Hitoshi Maeshima, Yuto Takebayashi, Motoyuki Higa, Mayu Takeda, Toru Nakamura, Shohei Nishimon, Takahiro Sannohe, Yuri Hotta, Ryo Hanzawa, Ryoko Higashiyama, Nobuto Shibata, Heii Arai. Significance of measurements of peripheral carbonyl stress markers in a cross-sectional and longitudinal study in patients with acute-stage schizophrenia. Schizophrenia bulletin. 2014 Nov; 40(6):1366-73. doi: 10.1093/schbul/sbt234. [PMID: 24448481]
  • Makoto Arai, Mitsuhiro Miyashita, Akiko Kobori, Kazuya Toriumi, Yasue Horiuchi, Masanari Itokawa. Carbonyl stress and schizophrenia. Psychiatry and clinical neurosciences. 2014 Sep; 68(9):655-65. doi: 10.1111/pcn.12216. [PMID: 24995521]
  • Monique Albersen, Marjolein Bosma, Jurjen J Luykx, Judith J M Jans, Steven C Bakker, Eric Strengman, Paul J Borgdorff, Peter J M Keijzers, Eric P A van Dongen, Peter Bruins, Monique G M de Sain-van der Velden, Gepke Visser, Nine V V A M Knoers, Roel A Ophoff, Nanda M Verhoeven-Duif. Vitamin B-6 vitamers in human plasma and cerebrospinal fluid. The American journal of clinical nutrition. 2014 Aug; 100(2):587-92. doi: 10.3945/ajcn.113.082008. [PMID: 24808484]
  • Arve Ulvik, Øivind Midttun, Eva R Pedersen, Simone Jpm Eussen, Ottar Nygård, Per M Ueland. Evidence for increased catabolism of vitamin B-6 during systemic inflammation. The American journal of clinical nutrition. 2014 Jul; 100(1):250-5. doi: 10.3945/ajcn.114.083196. [PMID: 24808485]
  • Peipei Zhang, Sofya Suidasari, Tomomi Hasegawa, Noriyuki Yanaka, Norihisa Kato. Vitamin B₆ activates p53 and elevates p21 gene expression in cancer cells and the mouse colon. Oncology reports. 2014 May; 31(5):2371-6. doi: 10.3892/or.2014.3073. [PMID: 24626782]
  • Masato Kobayashi, Takeo Nakanishi, Kodai Nishi, Yusuke Higaki, Hiroyuki Okudaira, Masahiro Ono, Takafumi Tsujiuchi, Asuka Mizutani, Ryuichi Nishii, Ikumi Tamai, Yasushi Arano, Keiichi Kawai. Transport mechanisms of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan. Nuclear medicine and biology. 2014 Apr; 41(4):338-42. doi: 10.1016/j.nucmedbio.2014.01.004. [PMID: 24607436]
  • Keisuke Kuwahara, Akiko Nanri, Ngoc Minh Pham, Kayo Kurotani, Ayami Kume, Masao Sato, Kazuaki Kawai, Hiroshi Kasai, Tetsuya Mizoue. Serum vitamin B6, folate, and homocysteine concentrations and oxidative DNA damage in Japanese men and women. Nutrition (Burbank, Los Angeles County, Calif.). 2013 Oct; 29(10):1219-23. doi: 10.1016/j.nut.2013.03.014. [PMID: 23800563]
  • A Nanri, N M Pham, K Kurotani, A Kume, K Kuwahara, M Sato, H Hayabuchi, T Mizoue. Serum pyridoxal concentrations and depressive symptoms among Japanese adults: results from a prospective study. European journal of clinical nutrition. 2013 Oct; 67(10):1060-5. doi: 10.1038/ejcn.2013.115. [PMID: 23801094]
  • Mei Zhao, Maria A Ralat, Vanessa da Silva, Timothy J Garrett, Stephan Melnyk, S Jill James, Jesse F Gregory. Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells. American journal of physiology. Endocrinology and metabolism. 2013 Feb; 304(4):E342-51. doi: 10.1152/ajpendo.00359.2012. [PMID: 23211517]
  • Magdalena Jankowska, Marcin Marszałł, Alicja Dębska-Ślizień, Juan J Carrero, Bengt Lindholm, Wojciech Czarnowski, Bolesław Rutkowski, Piotr Trzonkowski. Vitamin B6 and the immunity in kidney transplant recipients. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 2013 Jan; 23(1):57-64. doi: 10.1053/j.jrn.2012.01.023. [PMID: 22445054]
  • Chen-Tai Hou, Ying-Hsun Wu, Chien-Hsiang Cheng, Pei-Ning Huang, Yi-Chia Huang. Higher plasma homocysteine is associated with lower vitamin B6 status in critically ill surgical patients. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 2012 Oct; 27(5):695-700. doi: 10.1177/0884533612449654. [PMID: 22868281]
  • Abu Hena Mostafa Kamal, Kun Cho, Da-Eun Kim, Nobuyuki Uozumi, Keun-Yook Chung, Sang Young Lee, Jong-Soon Choi, Seong-Woo Cho, Chang-Seob Shin, Sun Hee Woo. Changes in physiology and protein abundance in salt-stressed wheat chloroplasts. Molecular biology reports. 2012 Sep; 39(9):9059-74. doi: 10.1007/s11033-012-1777-7. [PMID: 22736107]
  • ShuoHao Huang, JianYun Zhang, YaPing Ma, Shu Wei, LongQuan Huang. Characterization of an acid phosphatase responsible for hydrolysis of pyridoxal 5'-phosphate in tobacco plants. Plant physiology and biochemistry : PPB. 2012 Aug; 57(?):114-9. doi: 10.1016/j.plaphy.2012.05.017. [PMID: 22698754]
  • F C Polizzi, G Andican, E Çetin, S Civelek, V Yumuk, G Burçak. Increased DNA-glycation in type 2 diabetic patients: the effect of thiamine and pyridoxine therapy. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 2012 Jun; 120(6):329-34. doi: 10.1055/s-0031-1298016. [PMID: 22231921]
  • Anna Dietrich-Muszalska, Joanna Malinowska, Beata Olas, Rafal Głowacki, Edward Bald, Barbara Wachowicz, Jolanta Rabe-Jabłońska. The oxidative stress may be induced by the elevated homocysteine in schizophrenic patients. Neurochemical research. 2012 May; 37(5):1057-62. doi: 10.1007/s11064-012-0707-3. [PMID: 22270909]
  • Arve Ulvik, Øivind Midttun, Eva Ringdal Pedersen, Ottar Nygård, Per M Ueland. Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectoris. The American journal of clinical nutrition. 2012 May; 95(5):1072-8. doi: 10.3945/ajcn.111.029751. [PMID: 22492365]
  • Teruo Miyazawa, Kiyotaka Nakagawa, Satoko Shimasaki, Ryoji Nagai. Lipid glycation and protein glycation in diabetes and atherosclerosis. Amino acids. 2012 Apr; 42(4):1163-70. doi: 10.1007/s00726-010-0772-3. [PMID: 20957396]
  • Marco Vescovi, Michael Riefler, Micael Gessuti, Ondřej Novák, Thomas Schmülling, Fiorella Lo Schiavo. Programmed cell death induced by high levels of cytokinin in Arabidopsis cultured cells is mediated by the cytokinin receptor CRE1/AHK4. Journal of experimental botany. 2012 Apr; 63(7):2825-32. doi: 10.1093/jxb/ers008. [PMID: 22312114]
  • Louise Clement, Mallory Boylan, Virginia Miller, Judy Driskell, David Giraud, Hadil Subih. Vitamin B-6 vitamer levels in plasma and related symptoms in hemodialysis subjects taking low- and high-dose renal multivitamin supplements. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2012 Apr; 82(2):130-6. doi: 10.1024/0300-9831/a000102. [PMID: 23065838]
  • Michael P Whyte, Cheryl R Greenberg, Nada J Salman, Michael B Bober, William H McAlister, Deborah Wenkert, Bradley J Van Sickle, Jill H Simmons, Terence S Edgar, Martin L Bauer, Mohamed A Hamdan, Nick Bishop, Richard E Lutz, Mairead McGinn, Stanley Craig, Jean N Moore, John W Taylor, Robert H Cleveland, William R Cranley, Ruth Lim, Tom D Thacher, Jill E Mayhew, Matthew Downs, José Luis Millán, Alison M Skrinar, Philippe Crine, Hal Landy. Enzyme-replacement therapy in life-threatening hypophosphatasia. The New England journal of medicine. 2012 Mar; 366(10):904-13. doi: 10.1056/nejmoa1106173. [PMID: 22397652]
  • Bartolomé Vilanova, Jessica M Gallardo, Catalina Caldés, Miquel Adrover, Joaquín Ortega-Castro, Francisco Muñoz, Josefa Donoso. Formation of Schiff bases of O-phosphorylethanolamine and O-phospho-D,L-serine with pyridoxal 5'-phosphate. experimental and theoretical studies. The journal of physical chemistry. A. 2012 Mar; 116(8):1897-905. doi: 10.1021/jp2116033. [PMID: 22280506]
  • Scott J Lee, Thomas A Warnick, Sivakumar Pattathil, Jesús G Alvelo-Maurosa, Michelle J Serapiglia, Heather McCormick, Virginia Brown, Naomi F Young, Danny J Schnell, Lawrence B Smart, Michael G Hahn, Jeffrey F Pedersen, Susan B Leschine, Samuel P Hazen. Biological conversion assay using Clostridium phytofermentans to estimate plant feedstock quality. Biotechnology for biofuels. 2012 Feb; 5(?):5. doi: 10.1186/1754-6834-5-5. [PMID: 22316115]
  • Priscilla G Massé, Jaclyn Boudreau, Carole C Tranchant, Rodney Ouellette, Karen L Ericson. Type 1 diabetes impairs vitamin B(6) metabolism at an early stage of women's adulthood. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2012 Feb; 37(1):167-75. doi: 10.1139/h11-146. [PMID: 22288928]
  • Steinar Hustad, Simone Eussen, Øivind Midttun, Arve Ulvik, Puck M van de Kant, Lars Mørkrid, Randi Gislefoss, Per M Ueland. Kinetic modeling of storage effects on biomarkers related to B vitamin status and one-carbon metabolism. Clinical chemistry. 2012 Feb; 58(2):402-10. doi: 10.1373/clinchem.2011.174490. [PMID: 22194632]
  • Daniela Münch, Terry Roemer, Sang Ho Lee, Marianne Engeser, Hans Georg Sahl, Tanja Schneider. Identification and in vitro analysis of the GatD/MurT enzyme-complex catalyzing lipid II amidation in Staphylococcus aureus. PLoS pathogens. 2012 Jan; 8(1):e1002509. doi: 10.1371/journal.ppat.1002509. [PMID: 22291598]
  • John P Burand, Woojin Kim, Claudio L Afonso, Edan R Tulman, Gerald F Kutish, Zhiqiang Lu, Daniel L Rock. Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2. Viruses. 2012 01; 4(1):28-61. doi: 10.3390/v4010028. [PMID: 22355451]
  • Inga Kwiecień, Małgorzata Iciek, Lidia Włodek. Acceleration of anaerobic cysteine transformations to sulfane sulfur consequent to γ-glutamyl transpeptidase inhibition. TheScientificWorldJournal. 2012; 2012(?):253724. doi: 10.1100/2012/253724. [PMID: 22629124]
  • Kabo Masisi, Sofya Suidasari, Peipei Zhang, Yukako Okazaki, Noriyuki Yanaka, Norihisa Kato. Comparative study on the responses of concentrations of B₆-vitamers in several tissues of mice to the dietary level of pyridoxine. Journal of nutritional science and vitaminology. 2012; 58(6):446-51. doi: 10.3177/jnsv.58.446. [PMID: 23419405]
  • Michael Kube, Jelena Mitrovic, Bojan Duduk, Ralf Rabus, Erich Seemüller. Current view on phytoplasma genomes and encoded metabolism. TheScientificWorldJournal. 2012; 2012(?):185942. doi: 10.1100/2012/185942. [PMID: 22550465]
  • Masaru Mukai, Yoshihiro Sasaki, Jun-ichi Kikuchi. Fusion-triggered switching of enzymatic activity on an artificial cell membrane. Sensors (Basel, Switzerland). 2012; 12(5):5966-77. doi: 10.3390/s120505966. [PMID: 22778625]
  • Makoto Arai, Mitsuhiro Miyashita, Tomoe Ichikawa, Masanari Itokawa. [Schizophrenia and carbonyl stress]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. 2012; 114(2):101-7. doi: . [PMID: 22568112]
  • Huong Thi Viet Do, Youhei Ide, Andrew Njagi Mugo, Toshiharu Yagi. All-enzymatic HPLC method for determination of individual and total contents of vitamin B(6) in foods. Food & nutrition research. 2012; 56(?):. doi: 10.3402/fnr.v56i0.5409. [PMID: 22481897]
  • Partapjot S Grewal, Kanu Priya Gupta. Prosthetic rehabilitation of a young patient with Hypophosphatasia - A review and case report. Contemporary clinical dentistry. 2012 Jan; 3(1):74-7. doi: 10.4103/0976-237x.94551. [PMID: 22557902]
  • Shih-Chien Huang, James Cheng-Chung Wei, Ping-Ting Lin, Der Jinn Wu, Yi-Chia Huang. Plasma pyridoxal 5'-phosphate is not associated with inflammatory and immune responses after adjusting for serum albumin in patients with rheumatoid arthritis: a preliminary study. Annals of nutrition & metabolism. 2012; 60(2):83-9. doi: 10.1159/000336175. [PMID: 22353850]
  • Vijai Bhadauria, Sabine Banniza, Albert Vandenberg, Gopalan Selvaraj, Yangdou Wei. Peroxisomal alanine: glyoxylate aminotransferase AGT1 is indispensable for appressorium function of the rice blast pathogen, Magnaporthe oryzae. PloS one. 2012; 7(4):e36266. doi: 10.1371/journal.pone.0036266. [PMID: 22558413]
  • ShuoHao Huang, HaiBin Zeng, JianYun Zhang, Shu Wei, LongQuan Huang. Interconversions of different forms of vitamin B6 in tobacco plants. Phytochemistry. 2011 Dec; 72(17):2124-9. doi: 10.1016/j.phytochem.2011.07.019. [PMID: 21855952]
  • Hans Hartmann, Michael Fingerhut, Cornelis Jakobs, Barbara Plecko. Status epilepticus in a neonate treated with pyridoxine because of a familial recurrence risk for antiquitin deficiency: pyridoxine toxicity?. Developmental medicine and child neurology. 2011 Dec; 53(12):1150-3. doi: 10.1111/j.1469-8749.2011.04033.x. [PMID: 21707605]
  • Marta D Heis, Elisabeth M Ditmer, Luisa A de Oliveira, Ana Paula G Frazzon, Rogério Margis, Jeverson Frazzon. Differential expression of cysteine desulfurases in soybean. BMC plant biology. 2011 Nov; 11(?):166. doi: 10.1186/1471-2229-11-166. [PMID: 22099069]
  • ShuoHao Huang, HaiBin Zeng, JianYun Zhang, Shu Wei, LongQuan Huang. Characterization of enzymes involved in the interconversions of different forms of vitamin B(6) in tobacco leaves. Plant physiology and biochemistry : PPB. 2011 Nov; 49(11):1299-305. doi: 10.1016/j.plaphy.2011.08.008. [PMID: 22000053]
  • Eun-Jeong Lee, Peter J Facchini. Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy. Plant physiology. 2011 Nov; 157(3):1067-78. doi: 10.1104/pp.111.185512. [PMID: 21949209]
  • Stephanie M C Wilson, Brittney N Bivins, Katelyn A Russell, Lynn B Bailey. Oral contraceptive use: impact on folate, vitamin B₆, and vitamin B₁₂ status. Nutrition reviews. 2011 Oct; 69(10):572-83. doi: 10.1111/j.1753-4887.2011.00419.x. [PMID: 21967158]
  • Erzsébet Zavaczki, Viktória Jeney, Anupam Agarwal, Abolfazl Zarjou, Melinda Oros, Mónika Katkó, Zsuzsa Varga, György Balla, József Balla. Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney international. 2011 Oct; 80(7):731-9. doi: 10.1038/ki.2011.212. [PMID: 21716261]
  • Hiroyuki Tanaka, Miki Senda, Nagarajan Venugopalan, Atsushi Yamamoto, Toshiya Senda, Tetsuo Ishida, Kihachiro Horiike. Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney. The Journal of biological chemistry. 2011 Aug; 286(31):27548-58. doi: 10.1074/jbc.m110.201160. [PMID: 21676877]
  • Catalina Caldés, Bartolomé Vilanova, Miquel Adrover, Francisco Muñoz, Josefa Donoso. Understanding non-enzymatic aminophospholipid glycation and its inhibition. Polar head features affect the kinetics of Schiff base formation. Bioorganic & medicinal chemistry. 2011 Aug; 19(15):4536-43. doi: 10.1016/j.bmc.2011.06.018. [PMID: 21719301]
  • Rhea Mehta, Liana Dedina, Peter J O'Brien. Rescuing hepatocytes from iron-catalyzed oxidative stress using vitamins B1 and B6. Toxicology in vitro : an international journal published in association with BIBRA. 2011 Aug; 25(5):1114-22. doi: 10.1016/j.tiv.2011.03.015. [PMID: 21457772]
  • Shu-Chun Chuang, Rachael Stolzenberg-Solomon, Per Magne Ueland, Stein Emil Vollset, Øivind Midttun, Anja Olsen, Anne Tjønneland, Kim Overvad, Marie-Christine Boutron-Ruault, Sophie Morois, Françoise Clavel-Chapelon, Birgit Teucher, Rudolf Kaaks, Cornelia Weikert, Heiner Boeing, Antonia Trichopoulou, Vassiliki Benetou, Androniki Naska, Mazda Jenab, Nadia Slimani, Isabelle Romieu, Dominique S Michaud, Domenico Palli, Sabina Sieri, Salvatore Panico, Carlotta Sacerdote, Rosario Tumino, Guri Skeie, Eric J Duell, Laudina Rodriguez, Esther Molina-Montes, José Marı A Huerta, Nerea Larrañaga, Aurelio Barricarte Gurrea, Dorthe Johansen, Jonas Manjer, Weimin Ye, Malin Sund, Petra H M Peeters, Suzanne Jeurnink, Nicholas Wareham, Kay-Tee Khaw, Francesca Crowe, Elio Riboli, Bas Bueno-de-Mesquita, Paolo Vineis. A U-shaped relationship between plasma folate and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition. European journal of cancer (Oxford, England : 1990). 2011 Aug; 47(12):1808-16. doi: 10.1016/j.ejca.2011.02.007. [PMID: 21411310]
  • Hiroki Hasumi, Yayumi Kamiyama, Shinjiro Nakasora, Yasuhito Yamamoto, Mitsuhiko Hara, Yukihiko Fujita. Cerebrospinal fluid and serum levels of vitamin B6 in status epilepticus children. Brain & development. 2011 Aug; 33(7):580-8. doi: 10.1016/j.braindev.2010.10.002. [PMID: 21074958]
  • Stefan de Vogel, Jörn Schneede, Per Magne Ueland, Stein Emil Vollset, Klaus Meyer, Ase Fredriksen, Øivind Midttun, Tone Bjørge, Ellen Kampman, Michael Bretthauer, Geir Hoff. Biomarkers related to one-carbon metabolism as potential risk factors for distal colorectal adenomas. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2011 Aug; 20(8):1726-35. doi: 10.1158/1055-9965.epi-11-0359. [PMID: 21693628]
  • Chen-Tai Hou, Ying-Hsun Wu, Pei-Ning Huang, Chien-Hsiang Cheng, Yi-Chia Huang. Higher plasma pyridoxal 5'-phosphate is associated with better blood glucose responses in critically ill surgical patients with inadequate vitamin B-6 status. Clinical nutrition (Edinburgh, Scotland). 2011 Aug; 30(4):478-83. doi: 10.1016/j.clnu.2011.01.014. [PMID: 21349613]
  • Colin D Leasure, Hong-Yun Tong, Xue-Wen Hou, Amy Shelton, Mike Minton, Raymond Esquerra, Sanja Roje, Hanjo Hellmann, Zheng-Hui He. root uv-b sensitive mutants are suppressed by specific mutations in ASPARTATE AMINOTRANSFERASE2 and by exogenous vitamin B6. Molecular plant. 2011 Jul; 4(4):759-70. doi: 10.1093/mp/ssr033. [PMID: 21511809]
  • Kyle L Flannigan, Kathy D McCoy, John L Wallace. Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis. American journal of physiology. Gastrointestinal and liver physiology. 2011 Jul; 301(1):G188-93. doi: 10.1152/ajpgi.00105.2011. [PMID: 21474649]
  • Suk Weon Kim, Hye Jin Kim, Jong Hyun Kim, Yong Kook Kwon, Myung Suk Ahn, Young Pyo Jang, Jang R Liu. A rapid, simple method for the genetic discrimination of intact Arabidopsis thaliana mutant seeds using metabolic profiling by direct analysis in real-time mass spectrometry. Plant methods. 2011 Jun; 7(?):14. doi: 10.1186/1746-4811-7-14. [PMID: 21658279]
  • James B Adams, Tapan Audhya, Sharon McDonough-Means, Robert A Rubin, David Quig, Elizabeth Geis, Eva Gehn, Melissa Loresto, Jessica Mitchell, Sharon Atwood, Suzanne Barnhouse, Wondra Lee. Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. Nutrition & metabolism. 2011 Jun; 8(1):34. doi: 10.1186/1743-7075-8-34. [PMID: 21651783]
  • Arthur J L Cooper, Boris F Krasnikov, Zoya V Niatsetskaya, John T Pinto, Patrick S Callery, Maria T Villar, Antonio Artigues, Sam A Bruschi. Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents. Amino acids. 2011 Jun; 41(1):7-27. doi: 10.1007/s00726-010-0552-0. [PMID: 20306345]
  • Davide Gibellini, Francesco Alviano, Anna Miserocchi, Pier Luigi Tazzari, Francesca Ricci, Alberto Clò, Silvia Morini, Marco Borderi, Pierluigi Viale, Gianandrea Pasquinelli, Pasqualepaolo Pagliaro, Gian Paolo Bagnara, Maria Carla Re. HIV-1 and recombinant gp120 affect the survival and differentiation of human vessel wall-derived mesenchymal stem cells. Retrovirology. 2011 May; 8(?):40. doi: 10.1186/1742-4690-8-40. [PMID: 21612582]
  • Sonia Herrero, Eugenia González, Jeffrey W Gillikin, Heriberto Vélëz, Margaret E Daub. Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis. Plant molecular biology. 2011 May; 76(1-2):157-69. doi: 10.1007/s11103-011-9777-x. [PMID: 21533842]
  • Michael Gutensohn, Antje Klempien, Yasuhisa Kaminaga, Dinesh A Nagegowda, Florence Negre-Zakharov, Jung-Hyun Huh, Hongli Luo, Renate Weizbauer, Tesfaye Mengiste, Dorothea Tholl, Natalia Dudareva. Role of aromatic aldehyde synthase in wounding/herbivory response and flower scent production in different Arabidopsis ecotypes. The Plant journal : for cell and molecular biology. 2011 May; 66(4):591-602. doi: 10.1111/j.1365-313x.2011.04515.x. [PMID: 21284755]
  • Elena Bravo, Simonetta Palleschi, Patricia Aspichueta, Xabier Buqué, Barbara Rossi, Ainara Cano, Mariarosaria Napolitano, Begoña Ochoa, Kathleen M Botham. High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway. Lipids in health and disease. 2011 Apr; 10(?):60. doi: 10.1186/1476-511x-10-60. [PMID: 21504583]
  • Emma J Footitt, Simon J Heales, Philippa B Mills, George F G Allen, Marcus Oppenheim, Peter T Clayton. Pyridoxal 5'-phosphate in cerebrospinal fluid; factors affecting concentration. Journal of inherited metabolic disease. 2011 Apr; 34(2):529-38. doi: 10.1007/s10545-011-9279-7. [PMID: 21305354]
  • Fakhir S Al-Ani, Marwan S Al-Nimer, Fatima S Ali. Dyslipidemia as a contributory factor in etiopathogenesis of diabetic neuropathy. Indian journal of endocrinology and metabolism. 2011 Apr; 15(2):110-4. doi: 10.4103/2230-8210.81940. [PMID: 21731868]
  • Hsin-Yueh Chang, Jason T C Tzen, Su-Jen Lin, Yi-Ting Wu, En-Pei Isabel Chiang. Long-term prednisolone treatments increase bioactive vitamin B6 synthesis in vivo. The Journal of pharmacology and experimental therapeutics. 2011 Apr; 337(1):102-9. doi: 10.1124/jpet.110.174839. [PMID: 21205917]
  • Yen-lin Lin, Jiali Gao. Kinetic isotope effects of L-Dopa decarboxylase. Journal of the American Chemical Society. 2011 Mar; 133(12):4398-403. doi: 10.1021/ja108209w. [PMID: 21366322]