Cholesterol sulfate (BioDeep_00000012044)

 

Secondary id: BioDeep_00000229589, BioDeep_00000638235

human metabolite Endogenous blood metabolite natural product


代谢物信息卡片


[(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl]oxidanesulfonic acid

化学式: C27H46O4S (466.3117)
中文名称: 胆甾醇硫酸盐, 硫酸化胆固醇, 胆固醇硫酸酯
谱图信息: 最多检出来源 Homo sapiens(blood) 14.48%

Reviewed

Last reviewed on 2024-07-15.

Cite this Page

Cholesterol sulfate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/cholesterol_sulfate (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000012044). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OS(=O)(=O)O)C)C
InChI: InChI=1S/C27H46O4S/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30)/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

描述信息

Cholesterol sulfate, or cholest-5-en-3beta-ol sulfate, is an endogenous steroid and the C3beta sulfate ester of cholesterol. It is formed from cholesterol by steroid sulfotransferases (SSTs) such as SULT2B1b (also known as cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of cholesterol sulfate in the skin is implicated in the pathophysiology of X-linked ichthyosis, a congenital disorder in which STS is non-functional and the body cannot convert cholesterol sulfate back into cholesterol. Cholesterol sulfate is quantitatively the most important known sterol sulfate in human plasma, where it is present in a concentration that overlaps that of the other abundant circulating steroid sulfate, dehydroepiandrosterone (DHEA) sulfate (PMID 12730293). Cholesterol sulfate has a stabilizing function on the membrane, supports platelet adhesion and is involved in signal transduction (PMID 12730293). It plays a role in protecting erythrocytes from osmotic lysis and regulating sperm capacitation. Cholesterol sulfate can regulate the activity of serine proteases, e.g., those involved in blood clotting, fibrinolysis, and epidermal cell adhesion (PMID 12730293). As a result of its ability to regulate the activity of selective protein kinase C isoforms and modulate the specificity of phosphatidylinositol 3-kinase, cholesterol sulfate is involved in signal transduction (PMID 12730293). Cholesterol sulfate functions in keratinocyte differentiation, inducing genes that encode for key components involved in development of the barrier (PMID 12730293).
Cholesterol sulfate is a sterol sulfate in human plasma. It is a component of cell membrane and has a regulatory function. It has a stabilizing function on the membrane, supports platelet adhesion and involves in signal transduction. (PMID 12730293) [HMDB]
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D015842 - Serine Proteinase Inhibitors
D020011 - Protective Agents > D016588 - Anticarcinogenic Agents
D000970 - Antineoplastic Agents

同义名列表

44 个代谢物同义名

[(1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl]oxidanesulfonic acid; Cholesteryl sulfate, potassium salt, (3beta)-isomer; Cholesteryl sulfate, ammonium salt, (3beta)-isomer; Cholesteryl sulfate, sodium salt, 26-(14)C-labeled; Cholesteryl sulfate, sodium salt, (3beta)-isomer; Cholesteryl sulfate, 3H-labeled, (3beta)-isomer; CHOLEST-5-en-3-yl hydrogen sulphuric acid; CHOLEST-5-en-3-yl hydrogen sulfuric acid; cholest-5-en-3beta-yl hydrogen sulfate; Cholest-5-en-3beta-ol sulphuric acid; CHOLEST-5-en-3-yl hydrogen sulphate; Cholesterol hydrogen sulphuric acid; Cholest-5-en-3beta-ol sulfuric acid; Cholesterol hydrogen sulfuric acid; CHOLEST-5-EN-3-YL HYDROGEN SULFATE; Cholest-5-en-3β-ol sulphuric acid; Cholest-5-en-3b-ol sulphuric acid; Cholest-5-en-3b-ol sulfuric acid; Cholest-5-en-3β-ol sulfuric acid; Cholest-5-en-3beta-ol sulphate; Cholesterol hydrogen sulphate; Cholest-5-en-3beta-ol sulfate; Cholesterol hydrogen sulfate; Cholesterol 3-sulphuric acid; Cholesterol 3-sulfuric acid; Cholest-5-en-3β-ol sulphate; Cholest-5-en-3b-ol sulphate; Cholest-5-en-3β-ol sulfate; Cholest-5-en-3b-ol sulfate; Cholesterol sulphuric acid; Cholesteryl sulphuric acid; 5-Cholesten-3b-yl sulphate; 5-Cholesten-3b-yl sulfate; Cholesteryl sulfuric acid; Cholesterol sulfuric acid; Cholesterol 3-sulphate; Cholesterol 3-sulfate; Cholesterol sulphate; Cholesteryl sulphate; cholesteryl sulfate; cholesterol sulfate; DTXSID70401323; Cholesterol sulfate; Cholesterol sulfate



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

25 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 DOCK2, IVL, LORICRIN, SREBF2, SULT2B1
Peripheral membrane protein 3 CYP11A1, DOCK2, FDXR
Endosome membrane 1 LDLR
Endoplasmic reticulum membrane 4 HMGCR, SREBF2, STAR, STS
Mitochondrion membrane 1 CYP11A1
Nucleus 3 FLG, SREBF2, SULT2B1
cytosol 8 DOCK2, FLG, IVL, LORICRIN, PRKCQ, SREBF2, SULT2B1, TGM1
nuclear body 1 IVL
centrosome 1 IVL
nucleoplasm 2 LORICRIN, SREBF2
Cell membrane 3 CD8A, LDLR, STAR
Lipid-anchor 1 TGM1
Cytoplasmic granule 1 FLG
Multi-pass membrane protein 2 HMGCR, SREBF2
Golgi apparatus membrane 1 SREBF2
cell surface 2 LDLR, PLAU
glutamatergic synapse 1 FLG
Golgi apparatus 2 LDLR, STS
Golgi membrane 2 INS, SREBF2
mitochondrial inner membrane 2 CYP11A1, FDXR
postsynapse 1 FLG
Cytoplasm, cytosol 1 SULT2B1
Lysosome 2 LDLR, STS
endosome 1 STS
plasma membrane 10 CD8A, DOCK2, F2, FLG, LDLR, PLAU, PRKCQ, STAR, STS, TGM1
Membrane 7 CYP11A1, DOCK2, FLG, HMGCR, LDLR, STS, TGM1
basolateral plasma membrane 1 LDLR
extracellular exosome 7 DOCK2, F2, IVL, MMP7, PLAU, SULT2B1, TGM1
endoplasmic reticulum 4 HMGCR, SREBF2, STS, SULT2B1
extracellular space 4 F2, INS, MMP7, PLAU
mitochondrion 4 CYP11A1, FDX1, FDXR, STAR
intracellular membrane-bounded organelle 3 SREBF2, STS, SULT2B1
Single-pass type I membrane protein 3 CD8A, LDLR, STAR
Secreted 3 F2, INS, PLAU
extracellular region 7 CD8A, DOCK2, F2, FLG, INS, MMP7, PLAU
Single-pass membrane protein 1 LDLR
[Isoform 2]: Secreted 1 CD8A
Mitochondrion matrix 1 FDX1
mitochondrial matrix 4 CYP11A1, FDX1, FDXR, STAR
centriolar satellite 1 PRKCQ
external side of plasma membrane 3 CD8A, LDLR, PLAU
Secreted, extracellular space, extracellular matrix 1 MMP7
low-density lipoprotein particle 1 LDLR
cytoplasmic vesicle 1 FLG
Early endosome 1 LDLR
Membrane, clathrin-coated pit 1 LDLR
apical part of cell 1 LDLR
clathrin-coated pit 1 LDLR
Mitochondrion inner membrane 2 CYP11A1, FDXR
Cytoplasm, cytoskeleton 1 DOCK2
focal adhesion 1 PLAU
extracellular matrix 1 MMP7
peroxisomal membrane 1 HMGCR
mitochondrial intermembrane space 1 STAR
collagen-containing extracellular matrix 2 F2, FLG
Late endosome 1 LDLR
receptor complex 3 CD8A, FLG, LDLR
chromatin 1 SREBF2
cytoskeleton 1 DOCK2
cytoplasmic ribonucleoprotein granule 1 FLG
blood microparticle 1 F2
Endomembrane system 2 DOCK2, LDLR
endosome lumen 1 INS
sorting endosome 1 LDLR
Cornified envelope 4 FLG, IVL, LORICRIN, TGM1
specific granule membrane 1 PLAU
tertiary granule membrane 1 PLAU
Peroxisome membrane 1 HMGCR
Microsome 1 SULT2B1
plasma membrane raft 1 CD8A
secretory granule lumen 1 INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 3 F2, INS, STS
specific granule lumen 1 DOCK2
transport vesicle 1 INS
serine-type endopeptidase complex 1 PLAU
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
ER to Golgi transport vesicle membrane 1 SREBF2
clathrin-coated endocytic vesicle membrane 1 LDLR
endolysosome membrane 1 LDLR
SREBP-SCAP-Insig complex 1 SREBF2
[Isoform 1]: Cell membrane 1 CD8A
serine protease inhibitor complex 1 PLAU
somatodendritic compartment 1 LDLR
Cytoplasmic vesicle, COPII-coated vesicle membrane 1 SREBF2
protein complex involved in cell-matrix adhesion 1 PLAU
PCSK9-LDLR complex 1 LDLR
T cell receptor complex 1 CD8A
keratohyalin granule 1 FLG
Cytoplasmic vesicle, secretory vesicle, microneme membrane 1 STS
microneme membrane 1 STS
[Sterol regulatory element-binding protein 2]: Endoplasmic reticulum membrane 1 SREBF2
[Processed sterol regulatory element-binding protein 2]: Nucleus 1 SREBF2


文献列表

  • S Tokoro, T Ogawa, S Hayashi, K Igawa. High-resolution mass spectrometry imaging reveals skin lipid changes and the cholesterol sulphate cycle during keratinization. Journal of the European Academy of Dermatology and Venereology : JEADV. 2024 Jun; 38(6):e456-e458. doi: 10.1111/jdv.19621. [PMID: 37909310]
  • Yunling Wang, Jinyue Yang, Yuming Wang, Yaoguang Chang, Changhu Xue, Tiantian Zhang. Preparation and properties of fucoxanthin-loaded liposomes stabilized by sea cucumber derived cholesterol sulfate instead of cholesterol. Journal of bioscience and bioengineering. 2023 Feb; 135(2):160-166. doi: 10.1016/j.jbiosc.2022.11.004. [PMID: 36494249]
  • Kenji Morino, Kazufumi Kunimura, Yuki Sugiura, Yoshihiro Izumi, Keisuke Matsubara, Sayaka Akiyoshi, Rae Maeda, Kenichiro Hirotani, Daiji Sakata, Seiya Mizuno, Satoru Takahashi, Takeshi Bamba, Takehito Uruno, Yoshinori Fukui. Cholesterol sulfate limits neutrophil recruitment and gut inflammation during mucosal injury. Frontiers in immunology. 2023; 14(?):1131146. doi: 10.3389/fimmu.2023.1131146. [PMID: 37006281]
  • Fumika Mi-Ichi, Hiroshi Tsugawa, Makoto Arita, Hiroki Yoshida. Pleiotropic Roles of Cholesteryl Sulfate during Entamoeba Encystation: Involvement in Cell Rounding and Development of Membrane Impermeability. mSphere. 2022 08; 7(4):e0029922. doi: 10.1128/msphere.00299-22. [PMID: 35943216]
  • Takaaki Tatsuguchi, Takehito Uruno, Yuki Sugiura, Daiji Sakata, Yoshihiro Izumi, Tetsuya Sakurai, Yuko Hattori, Eiji Oki, Naoto Kubota, Koshiro Nishimoto, Masafumi Oyama, Kazufumi Kunimura, Takuto Ohki, Takeshi Bamba, Hideaki Tahara, Michiie Sakamoto, Masafumi Nakamura, Makoto Suematsu, Yoshinori Fukui. Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells. International immunology. 2022 04; 34(5):277-289. doi: 10.1093/intimm/dxac002. [PMID: 35094065]
  • Ferdinand Fandrei, Oskar Engberg, Lukáš Opálka, Pavla Jančálková, Petra Pullmannová, Miloš Steinhart, Andrej Kováčik, Kateřina Vávrová, Daniel Huster. Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability. Journal of lipid research. 2022 03; 63(3):100177. doi: 10.1016/j.jlr.2022.100177. [PMID: 35143845]
  • Hongyi Wu, Ruiyu Cao, Shukun Wei, Salma Pathan-Chhatbar, Maorong Wen, Bin Wu, Wolfgang W Schamel, Shuqing Wang, Bo OuYang. Cholesterol Binds in a Reversed Orientation to TCRβ-TM in Which Its OH Group is Localized to the Center of the Lipid Bilayer. Journal of molecular biology. 2021 12; 433(24):167328. doi: 10.1016/j.jmb.2021.167328. [PMID: 34688686]
  • Hila Emmert, Hansjörg Baurecht, Frederieke Thielking, Dora Stölzl, Elke Rodriguez, Inken Harder, Ehrhardt Proksch, Stephan Weidinger. Stratum corneum lipidomics analysis reveals altered ceramide profile in atopic dermatitis patients across body sites with correlated changes in skin microbiome. Experimental dermatology. 2021 10; 30(10):1398-1408. doi: 10.1111/exd.14185. [PMID: 32885529]
  • Ke Li, Michael J Siefkes, Weiming Li. Cervidins A-D: Novel Glycine Conjugated Fatty Acids from the Tarsal Gland of Male Whitetail Deer, Odocoileus virginianus. Journal of chemical ecology. 2021 Mar; 47(3):243-247. doi: 10.1007/s10886-021-01255-0. [PMID: 33629151]
  • Yan Wang, Haojie Jin, Yafang Wang, Yang Yao, Cuixia Yang, Jihong Meng, Xiaomu Tan, Yu Nie, Lixiang Xue, Baohui Xu, Heng Zhao, Feng Wang. Sult2b1 deficiency exacerbates ischemic stroke by promoting pro-inflammatory macrophage polarization in mice. Theranostics. 2021; 11(20):10074-10090. doi: 10.7150/thno.61646. [PMID: 34815805]
  • Shiva Kalantari, Saeed Chashmniam, Mohsen Nafar, Shiva Samavat, Danial Rezaie, Nooshin Dalili. A Noninvasive Urine Metabolome Panel as Potential Biomarkers for Diagnosis of T Cell-Mediated Renal Transplant Rejection. Omics : a journal of integrative biology. 2020 03; 24(3):140-147. doi: 10.1089/omi.2019.0158. [PMID: 32176594]
  • Anthony Castellanos, Mario Gomez Hernandez, Marjana Tomic-Canic, Ivan Jozic, Francisco Fernandez-Lima. Multimodal, in Situ Imaging of Ex Vivo Human Skin Reveals Decrease of Cholesterol Sulfate in the Neoepithelium during Acute Wound Healing. Analytical chemistry. 2020 01; 92(1):1386-1394. doi: 10.1021/acs.analchem.9b04542. [PMID: 31789498]
  • Jude Prah, Ali Winters, Kiran Chaudhari, Jessica Hersh, Ran Liu, Shao-Hua Yang. Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress. Brain research. 2019 11; 1723(?):146378. doi: 10.1016/j.brainres.2019.146378. [PMID: 31425677]
  • Masamitsu Maekawa, Aya Narita, Isamu Jinnoh, Takashi Iida, Thorsten Marquardt, Eugen Mengel, Yoshikatsu Eto, Peter T Clayton, Hiroaki Yamaguchi, Nariyasu Mano. Diagnostic performance evaluation of sulfate-conjugated cholesterol metabolites as urinary biomarkers of Niemann-Pick disease type C. Clinica chimica acta; international journal of clinical chemistry. 2019 Jul; 494(?):58-63. doi: 10.1016/j.cca.2019.03.1610. [PMID: 30876856]
  • Matteo Ludovici, Nina Kozul, Stefano Materazzi, Roberta Risoluti, Mauro Picardo, Emanuela Camera. Influence of the sebaceous gland density on the stratum corneum lipidome. Scientific reports. 2018 07; 8(1):11500. doi: 10.1038/s41598-018-29742-7. [PMID: 30065281]
  • Katharina Bakhaus, Josefine Bennien, Daniela Fietz, Alberto Sánchez-Guijo, Michaela Hartmann, Rosanna Serafini, Charles C Love, Andrei Golovko, Stefan A Wudy, Martin Bergmann, Joachim Geyer. Sodium-dependent organic anion transporter (Slc10a6-/-) knockout mice show normal spermatogenesis and reproduction, but elevated serum levels for cholesterol sulfate. The Journal of steroid biochemistry and molecular biology. 2018 05; 179(?):45-54. doi: 10.1016/j.jsbmb.2017.07.019. [PMID: 28743544]
  • Hisashi Johno, Kentaro Yoshimura, Yuki Mori, Tokuhide Kimura, Manabu Niimi, Masaki Yamada, Tetsuo Tanigawa, Jianglin Fan, Sen Takeda. Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry. Metabolomics : Official journal of the Metabolomic Society. 2018 02; 14(4):38. doi: 10.1007/s11306-018-1334-z. [PMID: 30830369]
  • Petra Pullmannová, Ludmila Pavlíková, Andrej Kováčik, Michaela Sochorová, Barbora Školová, Petr Slepička, Jaroslav Maixner, Jarmila Zbytovská, Kateřina Vávrová. Permeability and microstructure of model stratum corneum lipid membranes containing ceramides with long (C16) and very long (C24) acyl chains. Biophysical chemistry. 2017 05; 224(?):20-31. doi: 10.1016/j.bpc.2017.03.004. [PMID: 28363088]
  • Yang Li, Chengcheng Tang, Enbo Zhang, Li Yang. Electrostatically entrapped colistin liposomes for the treatment of Pseudomonas aeruginosa infection. Pharmaceutical development and technology. 2017 May; 22(3):436-444. doi: 10.1080/10837450.2016.1228666. [PMID: 27576012]
  • Andrej Kováčik, Michaela Šilarová, Petra Pullmannová, Jaroslav Maixner, Kateřina Vávrová. Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes. Langmuir : the ACS journal of surfaces and colloids. 2017 03; 33(11):2890-2899. doi: 10.1021/acs.langmuir.7b00184. [PMID: 28230380]
  • Zhengyang Wang, Xiaoming Yang, Liang Chen, Xiuling Zhi, Hanyu Lu, Yanxia Ning, Joe Yeong, Sifeng Chen, Lianhua Yin, Xinhong Wang, Xiaobo Li. Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury. Archives of toxicology. 2017 Jan; 91(1):271-287. doi: 10.1007/s00204-016-1693-z. [PMID: 27052460]
  • Praveen Kumar Gaur, Shikha Mishra, Suresh Purohit. Nanovesicles of nitrendipine with lipid complex for transdermal delivery: pharmacokinetic and pharmacodynamic studies. Artificial cells, nanomedicine, and biotechnology. 2016 Nov; 44(7):1684-93. doi: 10.3109/21691401.2015.1080170. [PMID: 26375758]
  • Yang Li, Lingling Huang, Chengcheng Tang, Enbo Zhang, Lei Ding, Li Yang. Preparation and characterisation of the colistin-entrapped liposome driven by electrostatic interaction for intravenous administration. Journal of microencapsulation. 2016 Aug; 33(5):427-37. doi: 10.1080/02652048.2016.1205153. [PMID: 27388548]
  • Matthew G K Benesch, Ruthven N A H Lewis, Ronald N McElhaney. A calorimetric and spectroscopic comparison of the effects of cholesterol and its sulfur-containing analogs thiocholesterol and cholesterol sulfate on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes. Biochimica et biophysica acta. 2016 Feb; 1858(2):168-80. doi: 10.1016/j.bbamem.2015.11.006. [PMID: 26585353]
  • Peter J Milianta, Michelle Muzzio, Jacqueline Denver, Geoffrey Cawley, Sunghee Lee. Water Permeability across Symmetric and Asymmetric Droplet Interface Bilayers: Interaction of Cholesterol Sulfate with DPhPC. Langmuir : the ACS journal of surfaces and colloids. 2015 Nov; 31(44):12187-96. doi: 10.1021/acs.langmuir.5b02748. [PMID: 26492572]
  • Alberto Sánchez-Guijo, Vinzenz Oji, Michaela F Hartmann, Heiko Traupe, Stefan A Wudy. Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS. Journal of lipid research. 2015 Sep; 56(9):1843-51. doi: 10.1194/jlr.d061499. [PMID: 26239050]
  • F Foglia, S E Rogers, J R P Webster, F A Akeroyd, K F Gascoyne, M J Lawrence, D J Barlow. Neutron Scattering Studies of the Effects of Formulating Amphotericin B with Cholesteryl Sulfate on the Drug's Interactions with Phospholipid and Phospholipid-Sterol Membranes. Langmuir : the ACS journal of surfaces and colloids. 2015 Jul; 31(29):8042-51. doi: 10.1021/acs.langmuir.5b01365. [PMID: 26139630]
  • Stephanie Seneff, Robert M Davidson, Ann Lauritzen, Anthony Samsel, Glyn Wainwright. A novel hypothesis for atherosclerosis as a cholesterol sulfate deficiency syndrome. Theoretical biology & medical modelling. 2015 May; 12(?):9. doi: 10.1186/s12976-015-0006-1. [PMID: 26014131]
  • Alberto Sánchez-Guijo, Vinzenz Oji, Michaela F Hartmann, Hans-Christian Schuppe, Heiko Traupe, Stefan A Wudy. High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency. Journal of lipid research. 2015 Feb; 56(2):403-12. doi: 10.1194/jlr.m055608. [PMID: 25502769]
  • Ana Reis, Alisa Rudnitskaya, Pajaree Chariyavilaskul, Neeraj Dhaun, Vanessa Melville, Jane Goddard, David J Webb, Andrew R Pitt, Corinne M Spickett. Top-down lipidomics of low density lipoprotein reveal altered lipid profiles in advanced chronic kidney disease. Journal of lipid research. 2015 Feb; 56(2):413-22. doi: 10.1194/jlr.m055624. [PMID: 25424003]
  • Barbora Školová, Klára Hudská, Petra Pullmannová, Andrej Kováčik, Karel Palát, Jaroslav Roh, Jana Fleddermann, Irina Estrela-Lopis, Kateřina Vávrová. Different phase behavior and packing of ceramides with long (C16) and very long (C24) acyls in model membranes: infrared spectroscopy using deuterated lipids. The journal of physical chemistry. B. 2014 Sep; 118(35):10460-70. doi: 10.1021/jp506407r. [PMID: 25122563]
  • Kazuhiro Yamamoto, Kaoru Miyazaki, Shouichi Higashi. Pericellular proteolysis by matrix metalloproteinase-7 is differentially modulated by cholesterol sulfate, sulfatide, and cardiolipin. The FEBS journal. 2014 Aug; 281(15):3346-56. doi: 10.1111/febs.12865. [PMID: 24903600]
  • Nicolas Desbenoit, Emilie Saussereau, Claudia Bich, Matthieu Bourderioux, Janine Fritsch, Aleksander Edelman, Alain Brunelle, Mario Ollero. Localized lipidomics in cystic fibrosis: TOF-SIMS imaging of lungs from Pseudomonas aeruginosa-infected mice. The international journal of biochemistry & cell biology. 2014 Jul; 52(?):77-82. doi: 10.1016/j.biocel.2014.01.026. [PMID: 24513532]
  • Barbora Skolová, Kateřina Jandovská, Petra Pullmannová, Ondřej Tesař, Jaroslav Roh, Alexandr Hrabálek, Kateřina Vávrová. The role of the trans double bond in skin barrier sphingolipids: permeability and infrared spectroscopic study of model ceramide and dihydroceramide membranes. Langmuir : the ACS journal of surfaces and colloids. 2014 May; 30(19):5527-35. doi: 10.1021/la500622f. [PMID: 24779554]
  • Peter M Elias, Mary L Williams, Eung-Ho Choi, Kenneth R Feingold. Role of cholesterol sulfate in epidermal structure and function: lessons from X-linked ichthyosis. Biochimica et biophysica acta. 2014 Mar; 1841(3):353-61. doi: 10.1016/j.bbalip.2013.11.009. [PMID: 24291327]
  • Praveen Kumar Gaur, Suresh Purohit, Yatendra Kumar, Shikha Mishra, Anil Bhandari. Preparation, characterization and permeation studies of a nanovesicular system containing diclofenac for transdermal delivery. Pharmaceutical development and technology. 2014 Feb; 19(1):48-54. doi: 10.3109/10837450.2012.751406. [PMID: 23281714]
  • Bonnie Mei-Wah Fong, Sidney Tam, Kelvin Sze-Yin Leung. Determination of plasma cholesterol sulfate by LC-APCI-MS/MS in the context of pediatric autism. Talanta. 2013 Nov; 116(?):115-21. doi: 10.1016/j.talanta.2013.04.075. [PMID: 24148381]
  • Yan Ma, HaiGang Li, ShiXia Guan. Characteristics and evaluation of an injectable clarithromycin lipid-based complex in vitro and in vivo. Drug delivery. 2013 Nov; 20(8):349-55. doi: 10.3109/10717544.2013.834415. [PMID: 24032596]
  • Sameer Agarwal, Cornelia Schroeder, Georg Schlechtingen, Tobias Braxmeier, Gary Jennings, Hans-Joachim Knölker. Evaluation of steroidal amines as lipid raft modulators and potential anti-influenza agents. Bioorganic & medicinal chemistry letters. 2013 Sep; 23(18):5165-9. doi: 10.1016/j.bmcl.2013.07.015. [PMID: 23916260]
  • André Engesland, Merete Skar, Terkel Hansen, Nataša Škalko-Basnet, Gøril Eide Flaten. New applications of phospholipid vesicle-based permeation assay: permeation model mimicking skin barrier. Journal of pharmaceutical sciences. 2013 May; 102(5):1588-600. doi: 10.1002/jps.23509. [PMID: 23529812]
  • Gelen Rodríguez, Mercedes Cócera, Laia Rubio, Cristina Alonso, Ramon Pons, Christophe Sandt, Paul Dumas, Carmen López-Iglesias, Alfons de la Maza, Olga López. Bicellar systems to modify the phase behaviour of skin stratum corneum lipids. Physical chemistry chemical physics : PCCP. 2012 Nov; 14(42):14523-33. doi: 10.1039/c2cp42421e. [PMID: 23011556]
  • Lóránt Markó, György Paragh, Péter Ugocsai, Alfred Boettcher, Thomas Vogt, Petra Schling, Attila Balogh, Victoria Tarabin, Evelyn Orsó, Norbert Wikonkál, József Mandl, Eva Remenyik, Gerd Schmitz. Keratinocyte ATP binding cassette transporter expression is regulated by ultraviolet light. Journal of photochemistry and photobiology. B, Biology. 2012 Nov; 116(?):79-88. doi: 10.1016/j.jphotobiol.2012.06.007. [PMID: 22982209]
  • Julieta Caballero, Gilles Frenette, Olivier D'Amours, Maurice Dufour, Richard Oko, Robert Sullivan. ATP-binding cassette transporter G2 activity in the bovine spermatozoa is modulated along the epididymal duct and at ejaculation. Biology of reproduction. 2012 Jun; 86(6):181. doi: 10.1095/biolreprod.111.097477. [PMID: 22441796]
  • Valentina Pirro, Livia S Eberlin, Paolo Oliveri, R Graham Cooks. Interactive hyperspectral approach for exploring and interpreting DESI-MS images of cancerous and normal tissue sections. The Analyst. 2012 May; 137(10):2374-80. doi: 10.1039/c2an35122f. [PMID: 22493773]
  • Martin Kaczocha, Qingqing Lin, Lindsay D Nelson, Michelle K McKinney, Benjamin F Cravatt, Erwin London, Dale G Deutsch. Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion. ACS chemical neuroscience. 2012 May; 3(5):364-8. doi: 10.1021/cn300001w. [PMID: 22860204]
  • Kirtisudha Mishra, Vineeta Vijay Batra, Srikanta Basu, Bimbadhar Rath, Renu Saxena. Steroid-resistant nephrotic syndrome associated with steroid sulfatase deficiency-x-linked recessive ichthyosis: a case report and review of literature. European journal of pediatrics. 2012 May; 171(5):847-50. doi: 10.1007/s00431-012-1712-x. [PMID: 22419362]
  • Eun-Jin Kim, Young-Sil Yoon, Suckchang Hong, Ho-Young Son, Tae-Young Na, Min-Ho Lee, Hyun-Jin Kang, Jinyoung Park, Won-Jea Cho, Sang-Gun Kim, Seung-Hoi Koo, Hyeung-geun Park, Mi-Ock Lee. Retinoic acid receptor-related orphan receptor α-induced activation of adenosine monophosphate-activated protein kinase results in attenuation of hepatic steatosis. Hepatology (Baltimore, Md.). 2012 May; 55(5):1379-88. doi: 10.1002/hep.25529. [PMID: 22183856]
  • Pei-Hsiu Kao, Yi-Ling Chiou, Ying-Jung Chen, Shinne-Ren Lin, Long-Sen Chang. Guanidination of notexin promotes its phospholipase A(2) activity-independent fusogenicity on vesicles with lipid-supplied negative curvature. Toxicon : official journal of the International Society on Toxinology. 2012 Jan; 59(1):47-58. doi: 10.1016/j.toxicon.2011.10.006. [PMID: 22030836]
  • Christine Crumbley, Yongjun Wang, Subhashis Banerjee, Thomas P Burris. Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor α (RORα). PloS one. 2012; 7(4):e33804. doi: 10.1371/journal.pone.0033804. [PMID: 22485150]
  • Songyin Huang, Nengyong Ouyang, Ling Lin, Lili Chen, Wei Wu, Fengxi Su, Yandan Yao, Herui Yao. HGF-induced PKCζ activation increases functional CXCR4 expression in human breast cancer cells. PloS one. 2012; 7(1):e29124. doi: 10.1371/journal.pone.0029124. [PMID: 22242160]
  • Hsin-I Chang, Ming-Kung Yeh. Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy. International journal of nanomedicine. 2012; 7(?):49-60. doi: 10.2147/ijn.s26766. [PMID: 22275822]
  • Jae Yoon Ko, Sun Mi Choi, Young Min Rhee, J L Beauchamp, Hugh I Kim. Studying interfacial reactions of cholesterol sulfate in an unsaturated phosphatidylglycerol layer with ozone using field induced droplet ionization mass spectrometry. Journal of the American Society for Mass Spectrometry. 2012 Jan; 23(1):141-52. doi: 10.1007/s13361-011-0275-9. [PMID: 22069038]
  • T N Engelbrecht, B Demé, B Dobner, R H H Neubert. Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin pharmacology and physiology. 2012; 25(4):200-7. doi: 10.1159/000338538. [PMID: 22614257]
  • Bruce C Campbell, Kathleen L Chan, Jong H Kim. Chemosensitization as a means to augment commercial antifungal agents. Frontiers in microbiology. 2012; 3(?):79. doi: 10.3389/fmicb.2012.00079. [PMID: 22393330]
  • Fumiko Zenri, Hisahiko Hiroi, Mikio Momoeda, Ryo Tsutsumi, Yumi Hosokawa, Minako Koizumi, Hanako Nakae, Yutaka Osuga, Tetsu Yano, Yuji Taketani. Expression of retinoic acid-related orphan receptor alpha and its responsive genes in human endometrium regulated by cholesterol sulfate. The Journal of steroid biochemistry and molecular biology. 2012 Jan; 128(1-2):21-8. doi: 10.1016/j.jsbmb.2011.10.001. [PMID: 22024429]
  • Won-Soo Lee. Integral hair lipid in human hair follicle. Journal of dermatological science. 2011 Dec; 64(3):153-8. doi: 10.1016/j.jdermsci.2011.08.004. [PMID: 21906914]
  • Sandra Méndez, Albert M Manich, Meritxell Martí, José L Parra, Luisa Coderch. Damaged hair retrieval with ceramide-rich liposomes. Journal of cosmetic science. 2011 Nov; 62(6):565-77. doi: ". [PMID: 22682400]
  • Hana Bak, Seung-Phil Hong, Se-Kyoo Jeong, Eung-Ho Choi, Sang E Lee, Seung-Hun Lee, Sung-Ku Ahn. Altered epidermal lipid layers induced by long-term exposure to suberythemal-dose ultraviolet. International journal of dermatology. 2011 Jul; 50(7):832-7. doi: 10.1111/j.1365-4632.2010.04789.x. [PMID: 21699519]
  • Peter M Elias, Debra Crumrine, Amy Paller, Marina Rodriguez-Martin, Mary L Williams. Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders. Dermato-endocrinology. 2011 Apr; 3(2):100-6. doi: 10.4161/derm.3.2.14831. [PMID: 21695019]
  • Franz Pw Radner, Susanne Grond, Guenter Haemmerle, Achim Lass, Rudolf Zechner. Fat in the skin: Triacylglycerol metabolism in keratinocytes and its role in the development of neutral lipid storage disease. Dermato-endocrinology. 2011 Apr; 3(2):77-83. doi: 10.4161/derm.3.2.15472. [PMID: 21695016]
  • Kenneth R Feingold, Yan J Jiang. The mechanisms by which lipids coordinately regulate the formation of the protein and lipid domains of the stratum corneum: Role of fatty acids, oxysterols, cholesterol sulfate and ceramides as signaling molecules. Dermato-endocrinology. 2011 Apr; 3(2):113-8. doi: 10.4161/derm.3.2.14996. [PMID: 21695021]
  • R Graham Cooks, Nicholas E Manicke, Allison L Dill, Demian R Ifa, Livia S Eberlin, Anthony B Costa, He Wang, Guangming Huang, Zheng Ouyang. New ionization methods and miniature mass spectrometers for biomedicine: DESI imaging for cancer diagnostics and paper spray ionization for therapeutic drug monitoring. Faraday discussions. 2011; 149(?):247-67; discussion 333. doi: 10.1039/c005327a. [PMID: 21413184]
  • Sutapa Mondal Roy, Munna Sarkar. Membrane fusion induced by small molecules and ions. Journal of lipids. 2011; 2011(?):528784. doi: 10.1155/2011/528784. [PMID: 21660306]
  • George Petrikkos, Miranda Drogari-Apiranthitou. Zygomycosis in Immunocompromised non-Haematological Patients. Mediterranean journal of hematology and infectious diseases. 2011; 3(1):e2011012. doi: 10.4084/mjhid.2011.012. [PMID: 21625316]
  • Caroline Chauvet, Amandine Vanhoutteghem, Christian Duhem, Gaëlle Saint-Auret, Brigitte Bois-Joyeux, Philippe Djian, Bart Staels, Jean-Louis Danan. Control of gene expression by the retinoic acid-related orphan receptor alpha in HepG2 human hepatoma cells. PloS one. 2011; 6(7):e22545. doi: 10.1371/journal.pone.0022545. [PMID: 21818335]
  • Natsuko Kawano, Kaoru Yoshida, Kenji Miyado, Manabu Yoshida. Lipid rafts: keys to sperm maturation, fertilization, and early embryogenesis. Journal of lipids. 2011; 2011(?):264706. doi: 10.1155/2011/264706. [PMID: 21490798]
  • Masao Iwamori, Yuriko Iwamori, Shigeki Adachi, Taisei Nomura. Excretion into feces of asialo GM1 in the murine digestive tract and Lactobacillus johnsonii exhibiting binding ability toward asialo GM1. A possible role of epithelial glycolipids in the discharge of intestinal bacteria. Glycoconjugate journal. 2011 Jan; 28(1):21-30. doi: 10.1007/s10719-010-9320-3. [PMID: 21174147]
  • G Fabbrocini, V De Vita, N Fardella, F Pastore, M C Annunziata, M C Mauriello, A Monfrecola, N Cameli. Skin needling to enhance depigmenting serum penetration in the treatment of melasma. Plastic surgery international. 2011; 2011(?):158241. doi: 10.1155/2011/158241. [PMID: 22567235]
  • Clark J Nelson, Jessica P Otis, Hannah V Carey. Global analysis of circulating metabolites in hibernating ground squirrels. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 2010 Dec; 5(4):265-73. doi: 10.1016/j.cbd.2010.07.002. [PMID: 20728417]
  • Yi-Ling Chiou, Shinne-Ren Lin, Long-Sen Chang. Lipid domain formation modulates activities of snake venom phospholipase A(2) enzymes. Toxicon : official journal of the International Society on Toxinology. 2010 Dec; 56(8):1362-71. doi: 10.1016/j.toxicon.2010.08.001. [PMID: 20705082]
  • Marc Brulet, Alexandre Seyer, Aleksander Edelman, Alain Brunelle, Janine Fritsch, Mario Ollero, Olivier Laprévote. Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice. Journal of lipid research. 2010 Oct; 51(10):3034-45. doi: 10.1194/jlr.m008870. [PMID: 20616379]
  • Kazuhiro Yamamoto, Kaoru Miyazaki, Shouichi Higashi. Cholesterol sulfate alters substrate preference of matrix metalloproteinase-7 and promotes degradations of pericellular laminin-332 and fibronectin. The Journal of biological chemistry. 2010 Sep; 285(37):28862-73. doi: 10.1074/jbc.m110.136994. [PMID: 20605794]
  • Rebecca A Shapiro, Amanda J Brindley, Rachel W Martin. Thermal stabilization of DMPC/DHPC bicelles by addition of cholesterol sulfate. Journal of the American Chemical Society. 2010 Aug; 132(33):11406-7. doi: 10.1021/ja1041012. [PMID: 20684512]
  • Natalia Yu Ryabova, M A Kiselev, S Dante, T Hauss, A M Balagurov. Investigation of stratum corneum lipid model membranes with free fatty acid composition by neutron diffraction. European biophysics journal : EBJ. 2010 Jul; 39(8):1167-76. doi: 10.1007/s00249-009-0569-z. [PMID: 20012954]
  • Yukio Niimura, Toshiko Moue, Nobuyoshi Takahashi, Ken-ichi Nagai. Modification of sphingoglycolipids and sulfolipids in kidney cell lines under heat stress: activation of monohexosylceramide synthesis as a ceramide scavenger. Glycobiology. 2010 Jun; 20(6):710-7. doi: 10.1093/glycob/cwq018. [PMID: 20157020]
  • Jennifer Ro, Joseph B Williams. Respiratory and cutaneous water loss of temperate-zone passerine birds. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2010 Jun; 156(2):237-46. doi: 10.1016/j.cbpa.2010.02.008. [PMID: 20167283]
  • Livia S Eberlin, Allison L Dill, Anthony B Costa, Demian R Ifa, Liang Cheng, Timothy Masterson, Michael Koch, Timothy L Ratliff, R Graham Cooks. Cholesterol sulfate imaging in human prostate cancer tissue by desorption electrospray ionization mass spectrometry. Analytical chemistry. 2010 May; 82(9):3430-4. doi: 10.1021/ac9029482. [PMID: 20373810]
  • Dhastagir Sultan Sheriff, Elshaari Farag Ali. Perspective on plasma membrane cholesterol efflux and spermatozoal function. Journal of human reproductive sciences. 2010 May; 3(2):68-75. doi: 10.4103/0974-1208.69337. [PMID: 21209749]
  • Niranjan M Deshpande, Manish G Gangrade, Maharudra B Kekare, Vikas V Vaidya. Determination of free and liposomal amphotericin B in human plasma by liquid chromatography-mass spectroscopy with solid phase extraction and protein precipitation techniques. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Feb; 878(3-4):315-26. doi: 10.1016/j.jchromb.2009.11.036. [PMID: 20022309]
  • Aldona Pietrzak, Anna Michalak-Stoma, Grazyna Chodorowska, Jacek C Szepietowski. Lipid disturbances in psoriasis: an update. Mediators of inflammation. 2010; 2010(?):. doi: 10.1155/2010/535612. [PMID: 20706605]
  • Jingsheng Xia, Dejian Ren. The BSA-induced Ca2+ influx during sperm capacitation is CATSPER channel-dependent. Reproductive biology and endocrinology : RB&E. 2009 Oct; 7(?):119. doi: 10.1186/1477-7827-7-119. [PMID: 19860887]
  • Thida Phoeung, Liliana Morfin Huber, Michel Lafleur. Cationic detergent/sterol mixtures can form fluid lamellar phases and stable unilamellar vesicles. Langmuir : the ACS journal of surfaces and colloids. 2009 May; 25(10):5778-84. doi: 10.1021/la804222w. [PMID: 19253957]
  • Clark J Nelson, Jessica P Otis, Sandra L Martin, Hannah V Carey. Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver. Physiological genomics. 2009 Mar; 37(1):43-51. doi: 10.1152/physiolgenomics.90323.2008. [PMID: 19106184]
  • Ernesto F Moreira, Ignacio M Larrayoz, Jung Wha Lee, Ignacio R Rodríguez. 7-Ketocholesterol is present in lipid deposits in the primate retina: potential implication in the induction of VEGF and CNV formation. Investigative ophthalmology & visual science. 2009 Feb; 50(2):523-32. doi: 10.1167/iovs.08-2373. [PMID: 18936140]
  • R Ramírez, M Martí, A Cavaco-Paulo, R Silva, A de la Maza, J L Parra, L Coderch. Liposome formation with wool lipid extracts rich in ceramides. Journal of liposome research. 2009; 19(1):77-83. doi: 10.1080/08982100802538838. [PMID: 19515010]
  • Melissa Runge-Morris, Thomas A Kocarek. Regulation of sulfotransferase and UDP-glucuronosyltransferase gene expression by the PPARs. PPAR research. 2009; 2009(?):728941. doi: 10.1155/2009/728941. [PMID: 19680455]
  • A N Zagryagskaya, D A Aleksandrov, M A Pushkareva, S I Galkina, Z V Grishina, G F Sud'ina. Biosynthesis of leukotriene B4 in human polymorphonuclear leukocytes: regulation by cholesterol and other lipids. Journal of immunotoxicology. 2008 Oct; 5(4):347-52. doi: 10.1080/15476910802482888. [PMID: 19404868]
  • Peter M Elias, Mary L Williams, Walter M Holleran, Yan J Jiang, Matthias Schmuth. Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism. Journal of lipid research. 2008 Apr; 49(4):697-714. doi: 10.1194/jlr.r800002-jlr200. [PMID: 18245815]
  • Keita Yunoki, Hajime Ishikawa, Yutaka Fukui, Masao Ohnishi. Chemical properties of epidermal lipids, especially sphingolipids, of the Antarctic minke whale. Lipids. 2008 Feb; 43(2):151-9. doi: 10.1007/s11745-007-3145-2. [PMID: 18188633]
  • Rodney E Infante, Arun Radhakrishnan, Lina Abi-Mosleh, Lisa N Kinch, Michael L Wang, Nick V Grishin, Joseph L Goldstein, Michael S Brown. Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop. The Journal of biological chemistry. 2008 Jan; 283(2):1064-75. doi: 10.1074/jbc.m707944200. [PMID: 17989072]
  • Ken-ichi Nagai, Keiko Tadano-Aritomi, Yukio Niimura, Ineo Ishizuka. Effect of nutritional substrate on sulfolipids metabolic turnover in isolated renal tubules from rat. Proceedings of the Japan Academy. Series B, Physical and biological sciences. 2008; 84(1):24-9. doi: 10.2183/pjab.84.24. [PMID: 18941285]
  • Guillaume Bastiat, Michel Lafleur. Phase behavior of palmitic acid/cholesterol/cholesterol sulfate mixtures and properties of the derived liposomes. The journal of physical chemistry. B. 2007 Sep; 111(37):10929-37. doi: 10.1021/jp0715833. [PMID: 17718556]
  • L Norlén, I Plasencia Gil, A Simonsen, P Descouts. Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films. Journal of structural biology. 2007 Jun; 158(3):386-400. doi: 10.1016/j.jsb.2006.12.006. [PMID: 17287132]
  • Sriram Krishnamurthy, Seema Kapoor, Sangeeta Yadav. Nephrotic syndrome with X-linked ichthyosis, Kallmann Syndrome and unilateral renal agenesis. Indian pediatrics. 2007 Apr; 44(4):301-3. doi: . [PMID: 17468528]
  • Marjolaine Arseneault, Michel Lafleur. Cholesterol sulfate and Ca(2+) modulate the mixing properties of lipids in stratum corneum model mixtures. Biophysical journal. 2007 Jan; 92(1):99-114. doi: 10.1529/biophysj.106.090167. [PMID: 17028138]
  • Heng-Ling Liou, Sayali S Dixit, Sujuan Xu, G Stephen Tint, Ann M Stock, Peter Lobel. NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols. The Journal of biological chemistry. 2006 Dec; 281(48):36710-23. doi: 10.1074/jbc.m608743200. [PMID: 17018531]
  • Yan J Jiang, Biao Lu, Peggy Kim, Peter M Elias, Kenneth R Feingold. Regulation of ABCA1 expression in human keratinocytes and murine epidermis. Journal of lipid research. 2006 Oct; 47(10):2248-58. doi: 10.1194/jlr.m600163-jlr200. [PMID: 16825673]
  • Nobuko Ito, Keiko Hirota, Kanako Momoeda, Masao Iwamori. Change in the concentration of neutrophil elastase in bronchoalveolar lavage fluid during anesthesia and its inhibition by cholesterol sulfate. Translational research : the journal of laboratory and clinical medicine. 2006 Aug; 148(2):96-102. doi: 10.1016/j.trsl.2006.04.001. [PMID: 16890150]
  • Dmitry A Aleksandrov, Anna N Zagryagskaya, Marina A Pushkareva, Markus Bachschmid, Marc Peters-Golden, Oliver Werz, Dieter Steinhilber, Galina F Sud'ina. Cholesterol and its anionic derivatives inhibit 5-lipoxygenase activation in polymorphonuclear leukocytes and MonoMac6 cells. The FEBS journal. 2006 Feb; 273(3):548-57. doi: 10.1111/j.1742-4658.2005.05087.x. [PMID: 16420478]