Latrunculin A (BioDeep_00000011473)
代谢物信息卡片
化学式: C22H31NO5S (421.19228360000005)
中文名称: 红海海绵素A
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC(=O)OC2CC(CCC(C)C=CC=CCC1)OC(O)(C1CSC(O)=N1)C2
InChI: InChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3+,7-5-,16-11-/t15-,17-,18-,19+,22-/m1/s1
描述信息
A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes.
同义名列表
5 个代谢物同义名
Latrunculin A; (4R)-4-[(1R,4E,8Z,10E,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one; (4R)-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-2-thiazolidinone; MS000025472; NSC 613011
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:69136
- KEGG: C16901
- PubChem: 445420
- PubChem: 6437378
- PubChem: 3891
- Metlin: METLIN64706
- DrugBank: DB02621
- ChEMBL: CHEMBL404116
- CAS: 76343-93-6
- PMhub: MS000025472
- MetaboLights: MTBLC69136
- PubChem: 135626075
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
20 个相关的物种来源信息
- 1162744 Cacospongia mycofijiensis:
- 344322 Negombata magnifica:
- 296243 Lasioseius: 10.1021/JO00250A053
- 436463 Hyattella: 10.1021/JO00250A053
- 262607 Chromodoris lochi:
- 121495 Thorectidae: 10.1021/NP50082A019
- 1162744 Cacospongia mycofijiensis:
- 508129 Chromodoris elisabethina: 10.1007/BF01952094
- 1174603 Chromodoris hamiltoni: 10.1016/0040-4020(95)00440-J
- 1162778 Dactylospongia: 10.1002/1099-0690(200102)2001:4<775::AID-EJOC775>3.0.CO;2-Z
- 1162744 Cacospongia mycofijiensis:
- 344322 Negombata magnifica:
- 296243 Lasioseius: 10.1021/JO00250A053
- 436463 Hyattella: 10.1021/JO00250A053
- 262607 Chromodoris lochi:
- 121495 Thorectidae: 10.1021/NP50082A019
- 1162744 Cacospongia mycofijiensis:
- 508129 Chromodoris elisabethina: 10.1007/BF01952094
- 1174603 Chromodoris hamiltoni: 10.1016/0040-4020(95)00440-J
- 1162778 Dactylospongia: 10.1002/1099-0690(200102)2001:4<775::AID-EJOC775>3.0.CO;2-Z
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Francisco Correa, Cristina Enríquez-Cortina, Alejandro Silva-Palacios, Nadia Román-Anguiano, Aurora Gil-Hernández, Marcos Ostolga-Chavarría, Elizabeth Soria-Castro, Sharik Hernández-Rizo, Paola de Los Heros, María Chávez-Canales, Cecilia Zazueta. Actin-Cytoskeleton Drives Caveolae Signaling to Mitochondria during Postconditioning.
Cells.
2023 02; 12(3):. doi:
10.3390/cells12030492
. [PMID: 36766835] - Zachary Savage, Cian Duggan, Alexia Toufexi, Pooja Pandey, Yuxi Liang, María Eugenia Segretin, Lok Him Yuen, David C A Gaboriau, Alexandre Y Leary, Yasin Tumtas, Virendrasinh Khandare, Andrew D Ward, Stanley W Botchway, Benji C Bateman, Indranil Pan, Martin Schattat, Imogen Sparkes, Tolga O Bozkurt. Chloroplasts alter their morphology and accumulate at the pathogen interface during infection by Phytophthora infestans.
The Plant journal : for cell and molecular biology.
2021 09; 107(6):1771-1787. doi:
10.1111/tpj.15416
. [PMID: 34250673] - Michael P Vincent, Trevor Stack, Amir Vahabikashi, Guorong Li, Kristin M Perkumas, Ruiyi Ren, Haiyan Gong, W Daniel Stamer, Mark Johnson, Evan A Scott. Surface Engineering of FLT4-Targeted Nanocarriers Enhances Cell-Softening Glaucoma Therapy.
ACS applied materials & interfaces.
2021 Jul; 13(28):32823-32836. doi:
10.1021/acsami.1c09294
. [PMID: 34232612] - Thaddäus Struk, Viji Nair, Felix Eichinger, Matthias Kretzler, Roland Wedlich-Söldner, Samet Bayraktar, Hermann Pavenstädt. Transcriptome analysis of primary podocytes reveals novel calcium regulated regulatory networks.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 11; 34(11):14490-14506. doi:
10.1096/fj.201902493rr
. [PMID: 32931033] - Conrad V Simoben, Ammar Qaseem, Aurélien F A Moumbock, Kiran K Telukunta, Stefan Günther, Wolfgang Sippl, Fidele Ntie-Kang. Pharmacoinformatic Investigation of Medicinal Plants from East Africa.
Molecular informatics.
2020 11; 39(11):e2000163. doi:
10.1002/minf.202000163
. [PMID: 32964659] - Arjen M Krikken, Huala Wu, Rinse de Boer, Damien P Devos, Tim P Levine, Ida J van der Klei. Peroxisome retention involves Inp1-dependent peroxisome-plasma membrane contact sites in yeast.
The Journal of cell biology.
2020 10; 219(10):. doi:
10.1083/jcb.201906023
. [PMID: 32805027] - Nathaniel J Hogrebe, Punn Augsornworawat, Kristina G Maxwell, Leonardo Velazco-Cruz, Jeffrey R Millman. Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells.
Nature biotechnology.
2020 04; 38(4):460-470. doi:
10.1038/s41587-020-0430-6
. [PMID: 32094658] - Karl Swärd, Katarzyna K Krawczyk, Björn Morén, Baoyi Zhu, Ljubica Matic, Johan Holmberg, Ulf Hedin, Bengt Uvelius, Karin Stenkula, Catarina Rippe. Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators.
American journal of physiology. Cell physiology.
2019 12; 317(6):C1128-C1142. doi:
10.1152/ajpcell.00047.2019
. [PMID: 31461342] - Marjatta Raudaskoski. The central role of septa in the basidiomycete Schizophyllum commune hyphal morphogenesis.
Fungal biology.
2019 09; 123(9):638-649. doi:
10.1016/j.funbio.2019.05.009
. [PMID: 31416583] - Bastian Rouven Brückner, Helen Nöding, Mark Skamrahl, Andreas Janshoff. Mechanical and morphological response of confluent epithelial cell layers to reinforcement and dissolution of the F-actin cytoskeleton.
Progress in biophysics and molecular biology.
2019 07; 144(?):77-90. doi:
10.1016/j.pbiomolbio.2018.08.010
. [PMID: 30197289] - Filip Vasilev, Nunzia Limatola, Dae-Ryoung Park, Uh-Hyun Kim, Luigia Santella, Jong Tai Chun. Disassembly of Subplasmalemmal Actin Filaments Induces Cytosolic Ca2+ Increases in Astropecten aranciacus Eggs.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2018; 48(5):2011-2034. doi:
10.1159/000492523
. [PMID: 30099438] - Ping Liu, Violetta Weinreb, Marc Ridilla, Laurie Betts, Pratik Patel, Aravinda M de Silva, Nancy L Thompson, Ken Jacobson. Rapid, directed transport of DC-SIGN clusters in the plasma membrane.
Science advances.
2017 11; 3(11):eaao1616. doi:
10.1126/sciadv.aao1616
. [PMID: 29134199] - Xin-Hua Liao, Alan R Kimmel. A Unique High-Throughput Assay to Identify Novel Small Molecule Inhibitors of Chemotaxis and Migration.
Current protocols in cell biology.
2017 Mar; 74(?):12.11.1-12.11.13. doi:
10.1002/cpcb.17
. [PMID: 28256720] - Xinhui Wang, LaNita Nichols, Elizabeth A Grunz-Borgmann, Zhe Sun, Gerald A Meininger, Timothy L Domeier, Christopher P Baines, Alan R Parrish. Fascin2 regulates cisplatin-induced apoptosis in NRK-52E cells.
Toxicology letters.
2017 Jan; 266(?):56-64. doi:
10.1016/j.toxlet.2016.11.021
. [PMID: 27989596] - Nozomi Yamaoka, Yasutaka Suetomo, Tohru Yoshihisa, Seiji Sonobe. Motion analysis and ultrastructural study of a colonial diatom, Bacillaria paxillifer.
Microscopy (Oxford, England).
2016 06; 65(3):211-21. doi:
10.1093/jmicro/dfv375
. [PMID: 26754563] - Mika Toya, Saeko Kobayashi, Miwa Kawasaki, Go Shioi, Mari Kaneko, Takashi Ishiuchi, Kazuyo Misaki, Wenxiang Meng, Masatoshi Takeichi. CAMSAP3 orients the apical-to-basal polarity of microtubule arrays in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America.
2016 Jan; 113(2):332-7. doi:
10.1073/pnas.1520638113
. [PMID: 26715742] - Janna V Serbo, Scot Kuo, Shawna Lewis, Matthew Lehmann, Jiuru Li, David H Gracias, Lewis H Romer. Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton.
Advanced healthcare materials.
2016 Jan; 5(1):146-58. doi:
10.1002/adhm.201500030
. [PMID: 26033825] - Addie E Embry, Hamid Mohammadi, Xinying Niu, Liping Liu, Borren Moe, William A Miller-Little, Christopher Y Lu, Leslie A Bruggeman, Christopher A McCulloch, Paul A Janmey, R Tyler Miller. Biochemical and Cellular Determinants of Renal Glomerular Elasticity.
PloS one.
2016; 11(12):e0167924. doi:
10.1371/journal.pone.0167924
. [PMID: 27942003] - Barbara Hissa, Luciana de Oliveira Andrade. Trypasonoma cruzi uses a specific subset of host cell lysosomes for cell invasion.
Parasitology international.
2015 Apr; 64(2):135-8. doi:
10.1016/j.parint.2014.11.005
. [PMID: 25463313] - Ljubica Perisic, Patricia Q Rodriguez, Kjell Hultenby, Ying Sun, Mark Lal, Christer Betsholtz, Mathias Uhlén, Annika Wernerson, Ulf Hedin, Timo Pikkarainen, Karl Tryggvason, Jaakko Patrakka. Schip1 is a novel podocyte foot process protein that mediates actin cytoskeleton rearrangements and forms a complex with Nherf2 and ezrin.
PloS one.
2015; 10(3):e0122067. doi:
10.1371/journal.pone.0122067
. [PMID: 25807495] - Rosemary G White. Probing plasmodesmata function with biochemical inhibitors.
Methods in molecular biology (Clifton, N.J.).
2015; 1217(?):199-227. doi:
10.1007/978-1-4939-1523-1_14
. [PMID: 25287206] - Germán Sierra-Paredes, Ana I Loureiro, Lyndon C Wright, Germán Sierra-Marcuño, Patrício Soares-da-Silva. Effects of eslicarbazepine acetate on acute and chronic latrunculin A-induced seizures and extracellular amino acid levels in the mouse hippocampus.
BMC neuroscience.
2014 Dec; 15(?):134. doi:
10.1186/s12868-014-0134-2
. [PMID: 25526768] - Richard D Evans, Christopher Robinson, Deborah A Briggs, David J Tooth, Jose S Ramalho, Marta Cantero, Lluis Montoliu, Shyamal Patel, Elena V Sviderskaya, Alistair N Hume. Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transport.
Current biology : CB.
2014 Aug; 24(15):1743-50. doi:
10.1016/j.cub.2014.06.019
. [PMID: 25065759] - Dong Meng, Zhaoyu Gu, Hui Yuan, Aide Wang, Wei Li, Qing Yang, Yuandi Zhu, Tianzhong Li. The microtubule cytoskeleton and pollen tube Golgi vesicle system are required for in vitro S-RNase internalization and gametic self-incompatibility in apple.
Plant & cell physiology.
2014 May; 55(5):977-89. doi:
10.1093/pcp/pcu031
. [PMID: 24503865] - Raphaël Trouillon, Andrew G Ewing. Actin controls the vesicular fraction of dopamine released during extended kiss and run exocytosis.
ACS chemical biology.
2014 Mar; 9(3):812-20. doi:
10.1021/cb400665f
. [PMID: 24400601] - Jeffrey S Dason, Alex J Smith, Leo Marin, Milton P Charlton. Cholesterol and F-actin are required for clustering of recycling synaptic vesicle proteins in the presynaptic plasma membrane.
The Journal of physiology.
2014 Feb; 592(4):621-33. doi:
10.1113/jphysiol.2013.265447
. [PMID: 24297851] - Joseph C Burns, Jeffrey T Corwin. Responses to cell loss become restricted as the supporting cells in mammalian vestibular organs grow thick junctional actin bands that develop high stability.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2014 Jan; 34(5):1998-2011. doi:
10.1523/jneurosci.4355-13.2014
. [PMID: 24478379] - Soheil Aghamohammadzadeh, Iwona I Smaczynska-de Rooij, Kathryn R Ayscough. An Abp1-dependent route of endocytosis functions when the classical endocytic pathway in yeast is inhibited.
PloS one.
2014; 9(7):e103311. doi:
10.1371/journal.pone.0103311
. [PMID: 25072293] - Spela Zemljič Jokhadar, Janja Majhenc, Saša Svetina, Urška Batista. Positioning of integrin β1, caveolin-1 and focal adhesion kinase on the adhered membrane of spreading cells.
Cell biology international.
2013 Dec; 37(12):1276-84. doi:
10.1002/cbin.10155
. [PMID: 23853048] - Irina V Majoul, Liang Gao, Eric Betzig, Daria Onichtchouk, Eugenia Butkevich, Yuri Kozlov, Feliksas Bukauskas, Michael V L Bennett, Jennifer Lippincott-Schwartz, Rainer Duden. Fast structural responses of gap junction membrane domains to AB5 toxins.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Oct; 110(44):E4125-33. doi:
10.1073/pnas.1315850110
. [PMID: 24133139] - Petra Mlcochova, Annegret Pelchen-Matthews, Mark Marsh. Organization and regulation of intracellular plasma membrane-connected HIV-1 assembly compartments in macrophages.
BMC biology.
2013 Aug; 11(?):89. doi:
10.1186/1741-7007-11-89
. [PMID: 23915020] - Jens B Hafke, Katrin Ehlers, Jens Föller, Sabina-Roxana Höll, Stefanie Becker, Aart J E van Bel. Involvement of the sieve element cytoskeleton in electrical responses to cold shocks.
Plant physiology.
2013 Jun; 162(2):707-19. doi:
10.1104/pp.113.216218
. [PMID: 23624858] - Nadav Ben-Dov, Rafi Korenstein. Actin-cytoskeleton rearrangement modulates proton-induced uptake.
Experimental cell research.
2013 Apr; 319(7):946-54. doi:
10.1016/j.yexcr.2013.01.017
. [PMID: 23384598] - P Preira, V Grandné, J-M Forel, S Gabriele, M Camara, O Theodoly. Passive circulating cell sorting by deformability using a microfluidic gradual filter.
Lab on a chip.
2013 Jan; 13(1):161-70. doi:
10.1039/c2lc40847c
. [PMID: 23147069] - Barbara Hissa, Bruno Pontes, Paula Magda S Roma, Ana Paula Alves, Carolina D Rocha, Thalita M Valverde, Pedro Henrique N Aguiar, Fernando P Almeida, Allan J Guimarães, Cristina Guatimosim, Aristóbolo M Silva, Maria C Fernandes, Norma W Andrews, Nathan B Viana, Oscar N Mesquita, Ubirajara Agero, Luciana O Andrade. Membrane cholesterol removal changes mechanical properties of cells and induces secretion of a specific pool of lysosomes.
PloS one.
2013; 8(12):e82988. doi:
10.1371/journal.pone.0082988
. [PMID: 24376622] - Huamei Forsman, Karin Önnheim, Emil Andréasson, Karin Christenson, Anna Karlsson, Johan Bylund, Claes Dahlgren. Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production.
PloS one.
2013; 8(3):e60169. doi:
10.1371/journal.pone.0060169
. [PMID: 23555913] - Sheel N Dandekar, Jason S Park, Grace E Peng, James J Onuffer, Wendell A Lim, Orion D Weiner. Actin dynamics rapidly reset chemoattractant receptor sensitivity following adaptation in neutrophils.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2013; 368(1629):20130008. doi:
10.1098/rstb.2013.0008
. [PMID: 24062580] - Jiamin Ye, Wenhua Zhang, Yan Guo. Arabidopsis SOS3 plays an important role in salt tolerance by mediating calcium-dependent microfilament reorganization.
Plant cell reports.
2013 Jan; 32(1):139-48. doi:
10.1007/s00299-012-1348-3
. [PMID: 23052592] - Hong Wang, Aileen X Wang, Eugene J Barrett. Insulin-induced endothelial cell cortical actin filament remodeling: a requirement for trans-endothelial insulin transport.
Molecular endocrinology (Baltimore, Md.).
2012 Aug; 26(8):1327-38. doi:
10.1210/me.2012-1003
. [PMID: 22734037] - Adam Bleckert, Huzefa Photowala, Simon Alford. Dual pools of actin at presynaptic terminals.
Journal of neurophysiology.
2012 Jun; 107(12):3479-92. doi:
10.1152/jn.00789.2011
. [PMID: 22457456] - Yael Lavi, Nir Gov, Michael Edidin, Levi A Gheber. Lifetime of major histocompatibility complex class-I membrane clusters is controlled by the actin cytoskeleton.
Biophysical journal.
2012 Apr; 102(7):1543-50. doi:
10.1016/j.bpj.2012.01.042
. [PMID: 22500754] - Ginny L Weibel, Michelle R Joshi, W Gray Jerome, Sandra R Bates, Kevin J Yu, Michael C Phillips, George H Rothblat. Cytoskeleton disruption in J774 macrophages: consequences for lipid droplet formation and cholesterol flux.
Biochimica et biophysica acta.
2012 Mar; 1821(3):464-72. doi:
10.1016/j.bbalip.2011.09.015
. [PMID: 22015387] - Takehiro Himaki, Yamato Mizobe, Kenichirou Tsuda, Masashi Suetomo, Hiroshi Yamakuchi, Kazuchika Miyoshi, Sonshin Takao, Mitsutoshi Yoshida. Effect of postactivation treatment with latrunculin A on in vitro and in vivo development of cloned embryos derived from kidney fibroblasts of an aged Clawn miniature boar.
The Journal of reproduction and development.
2012; 58(4):398-403. doi:
10.1262/jrd.11-083a
. [PMID: 22498812] - Laleh Sistani, Fredrik Dunér, Sunil Udumala, Kjell Hultenby, Mathias Uhlen, Christer Betsholtz, Karl Tryggvason, Annika Wernerson, Jaakko Patrakka. Pdlim2 is a novel actin-regulating protein of podocyte foot processes.
Kidney international.
2011 Nov; 80(10):1045-54. doi:
10.1038/ki.2011.231
. [PMID: 21814175] - Steeve Boulant, Comert Kural, Jean-Christophe Zeeh, Florent Ubelmann, Tomas Kirchhausen. Actin dynamics counteract membrane tension during clathrin-mediated endocytosis.
Nature cell biology.
2011 Aug; 13(9):1124-31. doi:
10.1038/ncb2307
. [PMID: 21841790] - S de Keijzer, J Galloway, G S Harms, P N Devreotes, P A Iglesias. Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane.
Biochimica et biophysica acta.
2011 Jun; 1808(6):1701-8. doi:
10.1016/j.bbamem.2011.02.009
. [PMID: 21334306] - Jie Wang, David A Richards. Spatial regulation of exocytic site and vesicle mobilization by the actin cytoskeleton.
PloS one.
2011; 6(12):e29162. doi:
10.1371/journal.pone.0029162
. [PMID: 22195014] - Mirella Bellocci, Gian Luca Sala, Federica Callegari, Gian Paolo Rossini. Azaspiracid-1 inhibits endocytosis of plasma membrane proteins in epithelial cells.
Toxicological sciences : an official journal of the Society of Toxicology.
2010 Sep; 117(1):109-21. doi:
10.1093/toxsci/kfq172
. [PMID: 20547569] - Nimita H Fifadara, Freddy Beer, Shoichiro Ono, Santa J Ono. Interaction between activated chemokine receptor 1 and FcepsilonRI at membrane rafts promotes communication and F-actin-rich cytoneme extensions between mast cells.
International immunology.
2010 Feb; 22(2):113-28. doi:
10.1093/intimm/dxp118
. [PMID: 20173038] - Carlos J Baier, Cristina E Gallegos, Valeria Levi, Francisco J Barrantes. Cholesterol modulation of nicotinic acetylcholine receptor surface mobility.
European biophysics journal : EBJ.
2010 Jan; 39(2):213-27. doi:
10.1007/s00249-009-0521-2
. [PMID: 19641915] - Joseph Cuschieri, Sana Sakr, Eileen Bulger, Megan Knoll, Saman Arbabi, Ronald V Maier. Oxidant alterations in CD16 expression are cytoskeletal induced.
Shock (Augusta, Ga.).
2009 Dec; 32(6):572-7. doi:
10.1097/shk.0b013e3181a72530
. [PMID: 19333136] - Laura Milan-Lobo, Ingrid Gsandtner, Erwin Gaubitzer, Dominik Rünzler, Florian Buchmayer, Gottfried Köhler, Antonello Bonci, Michael Freissmuth, Harald H Sitte. Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy.
Molecular pharmacology.
2009 Dec; 76(6):1196-210. doi:
10.1124/mol.109.059139
. [PMID: 19755522] - Siva A Vanapalli, Yixuan Li, Frieder Mugele, Michel H G Duits. On the origins of the universal dynamics of endogenous granules in mammalian cells.
Molecular & cellular biomechanics : MCB.
2009 Dec; 6(4):191-201. doi:
"
. [PMID: 19899443] - Günther Gerisch, Mary Ecke, Britta Schroth-Diez, Silke Gerwig, Ulrike Engel, Lucinda Maddera, Margaret Clarke. Self-organizing actin waves as planar phagocytic cup structures.
Cell adhesion & migration.
2009 Oct; 3(4):373-82. doi:
10.4161/cam.3.4.9708
. [PMID: 19855162] - Araceli Castillo-Romero, Gloria Leon-Avila, Armando Perez Rangel, Rafael Cortes Zarate, Carlos Garcia Tovar, Jose Manuel Hernandez. Participation of actin on Giardia lamblia growth and encystation.
PloS one.
2009 Sep; 4(9):e7156. doi:
10.1371/journal.pone.0007156
. [PMID: 19774081] - Silvia M Uriarte, Neelakshi R Jog, Gregory C Luerman, Samrath Bhimani, Richard A Ward, Kenneth R McLeish. Counterregulation of clathrin-mediated endocytosis by the actin and microtubular cytoskeleton in human neutrophils.
American journal of physiology. Cell physiology.
2009 Apr; 296(4):C857-67. doi:
10.1152/ajpcell.00454.2008
. [PMID: 19176760] - Feng Wang, Yanping Jing, Zhen Wang, Tonglin Mao, Jozef Samaj, Ming Yuan, Haiyun Ren. Arabidopsis profilin isoforms, PRF1 and PRF2 show distinctive binding activities and subcellular distributions.
Journal of integrative plant biology.
2009 Feb; 51(2):113-21. doi:
10.1111/j.1744-7909.2008.00781.x
. [PMID: 19200149] - Manos Mavrakis, Richa Rikhy, Jennifer Lippincott-Schwartz. Plasma membrane polarity and compartmentalization are established before cellularization in the fly embryo.
Developmental cell.
2009 Jan; 16(1):93-104. doi:
10.1016/j.devcel.2008.11.003
. [PMID: 19154721] - Kazumoto Murata, Atsushi Sakamoto. Impairment of clathrin-mediated endocytosis via cytoskeletal change by epithelial to fibroblastoid conversion in HepG2 cells: a possible mechanism of des-gamma-carboxy prothrombin production in hepatocellular carcinoma.
International journal of oncology.
2008 Dec; 33(6):1149-55. doi:
. [PMID: 19020747]
- Laurent Chesneau, Magali Prigent, Emmanuelle Boy-Marcotte, Jean Daraspe, Guillaume Fortier, Michel Jacquet, Jean-Marc Verbavatz, Marie-Hélène Cuif. Interdependence of the Ypt/RabGAP Gyp5p and Gyl1p for recruitment to the sites of polarized growth.
Traffic (Copenhagen, Denmark).
2008 Apr; 9(4):608-22. doi:
10.1111/j.1600-0854.2007.00699.x
. [PMID: 18182006] - Denise M Ray, Sherry L Spinelli, Stephen J Pollock, Thomas I Murant, Jamie J O'Brien, Neil Blumberg, Charles W Francis, Mark B Taubman, Richard P Phipps. Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles.
Thrombosis and haemostasis.
2008 Jan; 99(1):86-95. doi:
10.1160/th07-05-0328
. [PMID: 18217139] - I-Ju Chen, Hung-Lin Chen, Michael Demetriou. Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.
The Journal of biological chemistry.
2007 Nov; 282(48):35361-72. doi:
10.1074/jbc.m706923200
. [PMID: 17897956] - Patrick Lajoie, Emily A Partridge, Ginette Guay, Jacky G Goetz, Judy Pawling, Annick Lagana, Bharat Joshi, James W Dennis, Ivan R Nabi. Plasma membrane domain organization regulates EGFR signaling in tumor cells.
The Journal of cell biology.
2007 Oct; 179(2):341-56. doi:
10.1083/jcb.200611106
. [PMID: 17938246] - Fenny Wiradjaja, Lisa M Ooms, Sabina Tahirovic, Ellie Kuhne, Rodney J Devenish, Alan L Munn, Robert C Piper, Peter Mayinger, Christina A Mitchell. Inactivation of the phosphoinositide phosphatases Sac1p and Inp54p leads to accumulation of phosphatidylinositol 4,5-bisphosphate on vacuole membranes and vacuolar fusion defects.
The Journal of biological chemistry.
2007 Jun; 282(22):16295-307. doi:
10.1074/jbc.m701038200
. [PMID: 17392273] - Neelakshi R Jog, Madhavi J Rane, George Lominadze, Gregory C Luerman, Richard A Ward, Kenneth R McLeish. The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets.
American journal of physiology. Cell physiology.
2007 May; 292(5):C1690-700. doi:
10.1152/ajpcell.00384.2006
. [PMID: 17202227] - Shuang-Yan Gao, Chun-Yu Li, Tetsuya Shimokawa, Takehiro Terashita, Seiji Matsuda, Eishin Yaoita, Naoto Kobayashi. Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro.
Cell and tissue research.
2007 May; 328(2):391-400. doi:
10.1007/s00441-006-0365-3
. [PMID: 17265067] - Ilse Foissner, Geoffrey O Wasteneys. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells.
Plant & cell physiology.
2007 Apr; 48(4):585-97. doi:
10.1093/pcp/pcm030
. [PMID: 17327257] - Libin Liu, Mark P Jedrychowski, Steven P Gygi, Paul F Pilch. Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes.
Molecular biology of the cell.
2006 Oct; 17(10):4249-56. doi:
10.1091/mbc.e06-04-0278
. [PMID: 16870704] - Romesh A Draviam, Bing Wang, Juan Li, Xiao Xiao, Simon C Watkins. Mini-dystrophin efficiently incorporates into the dystrophin protein complex in living cells.
Journal of muscle research and cell motility.
2006; 27(1):53-67. doi:
10.1007/s10974-006-9055-8
. [PMID: 16496225] - Richard F Ransom, Nancy G Lam, Mark A Hallett, Simon J Atkinson, William E Smoyer. Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization.
Kidney international.
2005 Dec; 68(6):2473-83. doi:
10.1111/j.1523-1755.2005.00723.x
. [PMID: 16316324] - K Hörmanseder, G Obermeyer, I Foissner. Disturbance of endomembrane trafficking by brefeldin A and calyculin A reorganizes the actin cytoskeleton of Lilium longiflorum pollen tubes.
Protoplasma.
2005 Dec; 227(1):25-36. doi:
10.1007/s00709-005-0132-4
. [PMID: 16389491] - K R Ayscough. Coupling actin dynamics to the endocytic process in Saccharomyces cerevisiae.
Protoplasma.
2005 Oct; 226(1-2):81-8. doi:
10.1007/s00709-005-0107-5
. [PMID: 16231104] - Le Shen, Jerrold R Turner. Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis.
Molecular biology of the cell.
2005 Sep; 16(9):3919-36. doi:
10.1091/mbc.e04-12-1089
. [PMID: 15958494] - Tetsuya Takeda, Fred Chang. Role of fission yeast myosin I in organization of sterol-rich membrane domains.
Current biology : CB.
2005 Jul; 15(14):1331-6. doi:
10.1016/j.cub.2005.07.009
. [PMID: 16051179] - Maosong Qi, Elaine A Elion. Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3.
Journal of cell science.
2005 Jul; 118(Pt 13):2837-48. doi:
10.1242/jcs.02418
. [PMID: 15961405] - Thomas M Newpher, Robin P Smith, Vance Lemmon, Sandra K Lemmon. In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast.
Developmental cell.
2005 Jul; 9(1):87-98. doi:
10.1016/j.devcel.2005.04.014
. [PMID: 15992543] - Uta Fuchs, Isabel Manns, Gero Steinberg. Microtubules are dispensable for the initial pathogenic development but required for long-distance hyphal growth in the corn smut fungus Ustilago maydis.
Molecular biology of the cell.
2005 Jun; 16(6):2746-58. doi:
10.1091/mbc.e05-03-0176
. [PMID: 15829564] - Kirk J Czymmek, Timothy M Bourett, Ying Shao, Todd M DeZwaan, James A Sweigard, Richard J Howard. Live-cell imaging of tubulin in the filamentous fungus Magnaporthe grisea treated with anti-microtubule and anti-microfilament agents.
Protoplasma.
2005 Apr; 225(1-2):23-32. doi:
10.1007/s00709-004-0081-3
. [PMID: 15868210] - Eva-Maria Damm, Lucas Pelkmans, Jürgen Kartenbeck, Anna Mezzacasa, Teymuras Kurzchalia, Ari Helenius. Clathrin- and caveolin-1-independent endocytosis: entry of simian virus 40 into cells devoid of caveolae.
The Journal of cell biology.
2005 Jan; 168(3):477-88. doi:
10.1083/jcb.200407113
. [PMID: 15668298] - Kayoko Tsuda, Atsuo Amano, Kyohei Umebayashi, Hiroaki Inaba, Ichiro Nakagawa, Yoshinobu Nakanishi, Tamotsu Yoshimori. Molecular dissection of internalization of Porphyromonas gingivalis by cells using fluorescent beads coated with bacterial membrane vesicle.
Cell structure and function.
2005; 30(2):81-91. doi:
10.1247/csf.30.81
. [PMID: 16428861] - Kazuhiro Ishiguro, Zhifang Cao, Marco Lopez Ilasca, Takafumi Ando, Ramnik Xavier. Wave2 activates serum response element via its VCA region and functions downstream of Rac.
Experimental cell research.
2004 Dec; 301(2):331-7. doi:
10.1016/j.yexcr.2004.09.003
. [PMID: 15530867] - Katerina Malinska, Jan Malinsky, Miroslava Opekarova, Widmar Tanner. Distribution of Can1p into stable domains reflects lateral protein segregation within the plasma membrane of living S. cerevisiae cells.
Journal of cell science.
2004 Dec; 117(Pt 25):6031-41. doi:
10.1242/jcs.01493
. [PMID: 15536122] - Günther Gerisch, Till Bretschneider, Annette Müller-Taubenberger, Evelyn Simmeth, Mary Ecke, Stefan Diez, Kurt Anderson. Mobile actin clusters and traveling waves in cells recovering from actin depolymerization.
Biophysical journal.
2004 Nov; 87(5):3493-503. doi:
10.1529/biophysj.104.047589
. [PMID: 15347592] - Juan A Rosado, José J López, Alan G S Harper, Matthew T Harper, Pedro C Redondo, José A Pariente, Stewart O Sage, Ginés M Salido. Two pathways for store-mediated calcium entry differentially dependent on the actin cytoskeleton in human platelets.
The Journal of biological chemistry.
2004 Jul; 279(28):29231-5. doi:
10.1074/jbc.m403509200
. [PMID: 15136566] - Charlotte Immerstrand, Harriet M Nilsson, Margaretha Lindroth, Tommy Sundqvist, Karl-Eric Magnusson, Kajsa Holmgren Peterson. Height changes associated with pigment aggregation in Xenopus laevis melanophores.
Bioscience reports.
2004 Jun; 24(3):203-14. doi:
10.1007/s10540-005-2581-6
. [PMID: 16209129] - Stephen W Martin, James B Konopka. Lipid raft polarization contributes to hyphal growth in Candida albicans.
Eukaryotic cell.
2004 Jun; 3(3):675-84. doi:
10.1128/ec.3.3.675-684.2004
. [PMID: 15189988] - Shuang-Yan Gao, Chun-Yu Li, Jie Chen, Lei Pan, Shouichiro Saito, Takehiro Terashita, Kyoko Saito, Kyojy Miyawaki, Kazuhiro Shigemoto, Katsumi Mominoki, Seiji Matsuda, Naoto Kobayashi. Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation.
Nephron. Experimental nephrology.
2004; 97(2):e49-61. doi:
10.1159/000078406
. [PMID: 15218323] - Jeremy L Bricker, Shaoyou Chu, Stephen A Kempson. Disruption of F-actin stimulates hypertonic activation of the BGT1 transporter in MDCK cells.
American journal of physiology. Renal physiology.
2003 May; 284(5):F930-7. doi:
10.1152/ajprenal.00289.2002
. [PMID: 12527556] - Tatsuo Katata, Kenji Irie, Atsunori Fukuhara, Tomomi Kawakatsu, Akio Yamada, Kazuya Shimizu, Yoshimi Takai. Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells.
Oncogene.
2003 Apr; 22(14):2097-109. doi:
10.1038/sj.onc.1206255
. [PMID: 12687012] - Patricia Neco, Ornella Rossetto, Anabel Gil, Cesare Montecucco, Luis M Gutiérrez. Taipoxin induces F-actin fragmentation and enhances release of catecholamines in bovine chromaffin cells.
Journal of neurochemistry.
2003 Apr; 85(2):329-37. doi:
10.1046/j.1471-4159.2003.01682.x
. [PMID: 12675909] - Alejandro M Bertorello, Yulia Komarova, Kristen Smith, Ingo B Leibiger, Riad Efendiev, Carlos H Pedemonte, Gary Borisy, Jacob I Sznajder. Analysis of Na+,K+-ATPase motion and incorporation into the plasma membrane in response to G protein-coupled receptor signals in living cells.
Molecular biology of the cell.
2003 Mar; 14(3):1149-57. doi:
10.1091/mbc.e02-06-0367
. [PMID: 12631730] - H H C Tan, J A Thornhill, B H Al-Adhami, A Akhkha, J R Kusel. A study of the effect of surface damage on the uptake of Texas Red-BSA by schistosomula of Schistosoma mansoni.
Parasitology.
2003 Mar; 126(Pt 3):235-40. doi:
10.1017/s0031182002002846
. [PMID: 12666882] - Pedro C Redondo, Ana I Lajas, Ginés M Salido, Antonio Gonzalez, Juan A Rosado, José A Pariente. Evidence for secretion-like coupling involving pp60src in the activation and maintenance of store-mediated Ca2+ entry in mouse pancreatic acinar cells.
The Biochemical journal.
2003 Feb; 370(Pt 1):255-63. doi:
10.1042/bj20021505
. [PMID: 12423207] - Tijs Ketelaar, Norbert C A de Ruijter, Anne Mie C Emons. Unstable F-actin specifies the area and microtubule direction of cell expansion in Arabidopsis root hairs.
The Plant cell.
2003 Jan; 15(1):285-92. doi:
10.1105/tpc.007039
. [PMID: 12509537] - Warren D Marcus, Robert M Hochmuth. Experimental studies of membrane tethers formed from human neutrophils.
Annals of biomedical engineering.
2002 Nov; 30(10):1273-80. doi:
10.1114/1.1528614
. [PMID: 12540203] - Ghada A Nofal, Cheryl B Knudson. Latrunculin and cytochalasin decrease chondrocyte matrix retention.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
2002 Oct; 50(10):1313-24. doi:
10.1177/002215540205001004
. [PMID: 12364564] - Carmen García-Ruiz, Anna Colell, Albert Morales, María Calvo, Carlos Enrich, José C Fernández-Checa. Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha.
The Journal of biological chemistry.
2002 Sep; 277(39):36443-8. doi:
10.1074/jbc.m206021200
. [PMID: 12118012] - Peter White, Luo Gu, Jing Chen. Decreased actin solubility observed during ATP-depletion is mimicked by severing agents but not depolymerizing agents in isolated and cultured proximal tubular cells.
Clinical physiology and functional imaging.
2002 Sep; 22(5):312-9. doi:
10.1046/j.1475-097x.2002.00437.x
. [PMID: 12487003] - Takahiro Fujiwara, Ken Ritchie, Hideji Murakoshi, Ken Jacobson, Akihiro Kusumi. Phospholipids undergo hop diffusion in compartmentalized cell membrane.
The Journal of cell biology.
2002 Jun; 157(6):1071-81. doi:
10.1083/jcb.200202050
. [PMID: 12058021]