N'-nitrosonornicotine (BioDeep_00000011192)
Secondary id: BioDeep_00001871825
human metabolite
代谢物信息卡片
3-(1-nitrosopyrrolidin-2-yl)pyridine
化学式: C9H11N3O (177.09020759999999)
中文名称: (2S)-N’-亚硝基去甲烟碱, 去甲基烟碱亚硝胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c1cc(cnc1)C1CCCN1N=O
InChI: InChI=1S/C9H11N3O/c13-11-12-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5,7,9H,2,4,6H2
描述信息
N-nitrosonornicotine belongs to the family of Pyrrolidinylpyridines. These are compounds containing a pyrrolidinylpyridine ring system, which consists of a pyrrolidine ring linked to a pyridine ring.
D009676 - Noxae > D002273 - Carcinogens
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:80502
- KEGG: C16452
- PubChem: 27919
- HMDB: HMDB0041940
- Metlin: METLIN71204
- ChEMBL: CHEMBL434108
- Wikipedia: N-Nitrosonornicotine
- chemspider: 25973
- CAS: 53759-22-1
- CAS: 84237-38-7
- CAS: 16543-55-8
- CAS: 80508-23-2
- PMhub: MS000025153
- PubChem: 47205748
- NIKKAJI: J2.745F
- RefMet: N'-Nitrosonornicotine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Thomas Meikopoulos, Olga Begou, Theodoros Panagoulis, Eleni Kontogiannidou, Dimitrios G Fatouros, John H Miller, Georgios Theodoridis, Helen Gika. UHPLC-MS/MS method for the simultaneous determination of nicotine and tobacco-specific nitrosamines NNN and NNK for use in preclinical studies.
Analytical and bioanalytical chemistry.
2022 Nov; 414(27):7865-7875. doi:
10.1007/s00216-022-04319-6. [PMID: 36163593] - Nikola Pluym, Gerhard Scherer, Jeffery S Edmiston, Xiaohong C Jin, Mohamadi Sarkar, Max Scherer. Assessment of the Exposure to NNN in the Plasma of Smokeless Tobacco Users.
Chemical research in toxicology.
2022 04; 35(4):663-669. doi:
10.1021/acs.chemrestox.1c00431. [PMID: 35298127] - Sampada S Nikam, Murari Gurjar, Hitesh Singhavi, Anand Patil, Arjun Singh, Peter Villalta, Pankaj Chaturvedi, Samir S Khariwala, Vikram Gota, Irina Stepanov. Simultaneous analysis of urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, N'-nitrosonornicotine, and cotinine by liquid chromatography-tandem mass-spectrometry.
Scientific reports.
2021 10; 11(1):20007. doi:
10.1038/s41598-021-99259-z. [PMID: 34625573] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
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Head & neck.
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