Chloroxylenol (BioDeep_00000010103)

 

Secondary id: BioDeep_00000413156

human metabolite blood metabolite


代谢物信息卡片


2-Chloro-5-hydroxy-1,3-dimethylbenzene

化学式: C8H9ClO (156.0341894)
中文名称: 4-氯-3,5-二甲基苯酚
谱图信息: 最多检出来源 Homo sapiens(blood) 2.99%

分子结构信息

SMILES: CC1=CC(=CC(=C1Cl)C)O
InChI: InChI=1S/C8H9ClO/c1-5-3-7(10)4-6(2)8(5)9/h3-4,10H,1-2H3

描述信息

D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AE - Phenol and derivatives
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D004202 - Disinfectants
Same as: D03473

同义名列表

24 个代谢物同义名

2-Chloro-5-hydroxy-1,3-dimethylbenzene; 4-Chloro-1-hydroxy-3,5-dimethylbenzene; 4-Chloro-3,5-dimethylphenol sulfonate; Chloroxylenol, potassium salt; 4-chloro-3,5-dimethylphenol; 3,5-Dimethyl-4-chlorophenol; 2-Chloro-5-hydroxy-m-xylene; Chloroxylenol, sodium salt; Parachlorometaxylenol; p-Chloro-3,5-xylenol; p-Chloro-m-xylenol; 2-Chloro-m-xylenol; 4-Chloro-m-xylenol; Parametaxylenol; Chloroxylenolum; Chloro-xylenol; chloroxylenol; Cloroxilenol; Micro-guard; Sween prep; Ice-O-derm; Benzytol; Dettol; PCMX



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lawrence A Schachner, Ulrike Blume-Peytavi, Anneke Andriessen, Jan Izakovic, Annabel Maruani, Giuseppe Micali, Nikolay Murashkin, Carmen Salavastru, Antonio Torrelo. Algorithm to attenuate atopic dermatitis and for promoting a healthy skin barrier using skincare in newborns and infants. Italian journal of dermatology and venereology. 2023 Jun; 158(3):224-235. doi: 10.23736/s2784-8671.23.07336-x. [PMID: 37278500]
  • Marta Nowak-Lange, Katarzyna Niedziałkowska, Przemysław Bernat, Katarzyna Lisowska. In vitro study of the ecotoxicological risk of methylisothiazolinone and chloroxylenol towards soil bacteria. Scientific reports. 2022 11; 12(1):19068. doi: 10.1038/s41598-022-22981-9. [PMID: 36352006]
  • Jianhua Tan, Hongxuan Kuang, Congcong Wang, Jian Liu, Qihua Pang, Qilai Xie, Ruifang Fan. Human exposure and health risk assessment of an increasingly used antibacterial alternative in personal care products: Chloroxylenol. The Science of the total environment. 2021 Sep; 786(?):147524. doi: 10.1016/j.scitotenv.2021.147524. [PMID: 33975105]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Oluwatosin Obata, John Greenman, Halil Kurt, Kartik Chandran, Ioannis Ieropoulos. Resilience and limitations of MFC anodic community when exposed to antibacterial agents. Bioelectrochemistry (Amsterdam, Netherlands). 2020 Aug; 134(?):107500. doi: 10.1016/j.bioelechem.2020.107500. [PMID: 32299023]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
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  • Erol Capkin, Tuna Ozcelep, Sevki Kayis, Ilhan Altinok. Antimicrobial agents, triclosan, chloroxylenol, methylisothiazolinone and borax, used in cleaning had genotoxic and histopathologic effects on rainbow trout. Chemosphere. 2017 Sep; 182(?):720-729. doi: 10.1016/j.chemosphere.2017.05.093. [PMID: 28531838]
  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
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