Collettiside I (BioDeep_00000000101)

 

Secondary id: BioDeep_00000871957, BioDeep_00001867463

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(1S,2S,4S,5R,6R,7S,8R,9S,12S,13R,16S)-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2-oxane]-16-yl]oxyoxane-3,4,5-triol

化学式: C33H52O8 (576.3661992)
中文名称: 延龄草苷, 地索苷, 地索苷
谱图信息: 最多检出来源 Viridiplantae(plant) 45.09%

分子结构信息

SMILES: C1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)CC2[C@@](C)([C@@]3([H])CC[C@]4(C)[C@H]5[C@@H]([C@]6(O[C@H]5C[C@@]4([H])[C@]3([H])CC=2)CC[C@@H](C)CO6)C)C1
InChI: InChI=1S/C33H52O8/c1-17-7-12-33(38-16-17)18(2)26-24(41-33)14-23-21-6-5-19-13-20(8-10-31(19,3)22(21)9-11-32(23,26)4)39-30-29(37)28(36)27(35)25(15-34)40-30/h5,17-18,20-30,34-37H,6-16H2,1-4H3/t17-,18+,20+,21-,22+,23+,24+,25-,26+,27-,28+,29-,30-,31+,32+,33-/m1/s1

描述信息

Diosgenin 3-O-beta-D-glucoside is a sterol 3-beta-D-glucoside having diosgenin as the sterol component. It has a role as a metabolite. It is a sterol 3-beta-D-glucoside, a monosaccharide derivative, a hexacyclic triterpenoid and a spiroketal. It is functionally related to a diosgenin. It derives from a hydride of a spirostan.
Disogluside is a natural product found in Allium rotundum, Allium narcissiflorum, and other organisms with data available.
Capsicoside A3 is found in herbs and spices. Capsicoside A3 is a constituent of Capsicum annuum roots.
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].
Diosgenin glucoside, a saponin compound extracted from Trillium tschonoskii, provides neuroprotection by regulating microglial M1 polarization. Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosis [1][2].

同义名列表

45 个代谢物同义名

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(1S,2S,4S,5R,6R,7S,8R,9S,12S,13R,16S)-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2-oxane]-16-yl]oxyoxane-3,4,5-triol; 2-(hydroxymethyl)-6-{5,7,9,13-tetramethyl-5-oxaspiro[oxane-2,6-pentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosan]-18-eneoxy}oxane-3,4,5-triol; (3beta,25R)-Spirost-5-en-3-ol 3-O-beta-D-glucopyranoside; (25R)-spirost-5-en-3beta-ol 3-O-beta-D-glucopyranoside; (3beta,25R)-spirost-5-en-3-yl beta-D-glucopyranoside; (25R)-3beta-(beta-D-Glucopyranosyloxy)spirost-5-ene; (25R)-spirost-5-en-3beta-yl beta-D-glucopyranoside; Polygonatoside A, Lilioglycoside A, Melongoside B; (25R)-3B-(beta-D-Glucopyranosyloxy)spirost-5-ene; 25R-Spirost-5-en-3beta-yl-beta-D-glucopyranoside; b-D-Glucopyranoside, (3b,25R)-spirost-5-en-3-yl; 1H-Pyrrole-2,4-dicarboxylicacid, 3,5-dimethyl-; (3beta,25S)-isomer of diosgenin glucoside; spirost-5-en-3-yl beta-D-glucopyranoside; 3-O-(Glcbeta)-(25R)-spirost-5en-3beta-ol; diosgenin 3-O-beta-D-glucopyranoside; diosgenin 3-O-beta-D-glucoside; diosgenin 3-beta-D-glucoside; Disoglusido [INN-Spanish]; 3-O-beta-D-Glc-diosgenin; Disoglusidum [INN-Latin]; Diosgenin 3-glucoside; diosgenin glucoside; Diosgenin-glucoside; Diosgeninglucoside; Disogluside [INN]; Disogluside, inn; Polygonatoside a; Prosapogenin D?3; Collettinside I; UNII-8KI671F2NS; Prosapogenin D3; Collettiside I; Alliumoside a?; Melongoside B; Polyphyllin A; Alliumosid A; Disoglusidum; Funkioside A; Disoglusido; Disogluside; 8KI671F2NS; Diosgenin; Trillin; WA 185



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

37 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shaoxia Wang, Fujiang Wang, Hongyun Yang, Ruilin Li, Hong Guo, Limin Hu. Diosgenin glucoside provides neuroprotection by regulating microglial M1 polarization. International immunopharmacology. 2017 Sep; 50(?):22-29. doi: 10.1016/j.intimp.2017.06.008. [PMID: 28623715]
  • Liwu Chen, Jian Du, Qiwen Dai, Hongcheng Zhang, Wensheng Pang, Juan Hu. Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular docking. European journal of medicinal chemistry. 2014 Aug; 83(?):294-306. doi: 10.1016/j.ejmech.2014.06.037. [PMID: 24974349]
  • M R Malinow, W H Elliott, P McLaughlin, B Upson. Effects of synthetic glycosides on steroid balance in Macaca fascicularis. Journal of lipid research. 1987 Jan; 28(1):1-9. doi: . [PMID: 3559397]