Phenylpyruvate (BioDeep_00000001693)
Secondary id: BioDeep_00000405215, BioDeep_00000870067
natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019
代谢物信息卡片
2-Oxo-3-phenylpropanoic acid (Mixture oxo and keto)
化学式: C9H8O3 (164.0473)
中文名称: 苯丙酮酸钠, 苯丙酮酸
谱图信息:
最多检出来源 Homo sapiens(blood) 20.51%
Reviewed
Last reviewed on 2024-09-14.
Cite this Page
Phenylpyruvate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/phenylpyruvate (retrieved
2024-12-22) (BioDeep RN: BioDeep_00000001693). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C1=CC=C(C=C1)CC(=O)C(=O)O
InChI: InChI=1S/C9H8O3/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,11,12)
描述信息
Phenylpyruvic acid is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in blood or urine. High levels of phenylpyruvic acid can be found in the urine of individuals with phenylketonuria (PKU), an inborn error of metabolism. PKU is due to lack of the enzyme phenylalanine hydroxylase (PAH), so that phenylalanine is converted not to tyrosine but to phenylpyruvic acid. In particular, excessive phenylalanine can be metabolized into phenylketones through, a transaminase pathway route involving glutamate. Metabolites of this transamination reaction include phenylacetate, phenylpyruvate and phenethylamine. In persons with PKU, dietary phenylalanine either accumulates in the body or some of it is converted to phenylpyruvic acid. Individuals with PKU tend to excrete large quantities of phenylpyruvate, phenylacetate and phenyllactate, along with phenylalanine, in their urine. If untreated, mental retardation effects and microcephaly are evident by the first year along with other symptoms which include: unusual irritability, epileptic seizures and skin lesions. Hyperactivity, EEG abnormalities and seizures, and severe learning disabilities are major clinical problems later in life. A "musty or mousy" odor of skin, hair, sweat and urine (due to phenylacetate accumulation); and a tendency to hypopigmentation and eczema are also observed. The neural-development effects of PKU are primarily due to the disruption of neurotransmitter synthesis. In particular, phenylalanine is a large, neutral amino acid which moves across the blood-brain barrier (BBB) via the large neutral amino acid transporter (LNAAT). Excessive phenylalanine in the blood saturates the transporter. Thus, excessive levels of phenylalanine significantly decrease the levels of other LNAAs in the brain. But since these amino acids are required for protein and neurotransmitter synthesis, phenylalanine accumulation disrupts brain development, leading to mental retardation. Phenylpyruvic acid is also a microbial metabolite, it can be produced by Lactobacillus plantarum (PMID: 9687465).
Flavouring ingredient
Phenylpyruvic acid is used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase[1].
Phenylpyruvic acid is used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase[1].
同义名列表
48 个代谢物同义名
2-Oxo-3-phenylpropanoic acid (Mixture oxo and keto); alpha-Oxo-benzenepropanoic acid; alpha-Oxobenzenepropionic acid; α-Ketohydrocinnamic acid; alpha-Oxobenzenepropanoic acid; 2-Oxo-3-phenylpropanoic acid; 3-Phenyl-2-oxopropionic acid; alpha-Ketohydrocinnamic acid; 3-Phenyl-2-oxopropanoic acid; 2-Oxo-3-phenylpropionic acid; alpha-Oxo-benzenepropanoate; a-Oxo-benzenepropanoic acid; α-Oxo-benzenepropanoic acid; α-Ketohydrocinnamate; α-Oxobenzenepropionic acid; α-Oxobenzenepropanoic acid; β-Phenylpyruvic acid; Phenylbrenztraubensaeure; 3-Phenyl-2-oxopropanoate; 2-Oxo-3-phenylpropanoate; alpha-Ketohydrocinnamate; α-Ketohydrocinnamic acid; a-Ketohydrocinnamic acid; a-Oxo-benzenepropanoate; beta-Phenylpyruvic acid; keto-Phenylpyruvic acid; α-Oxo-benzenepropanoate; a-Hydroxycinnamic acid; Phenylpyroracemic acid; β-Phenylpyruvate; Sodium phenylpyruvate; a-Ketohydrocinnamate; α-Ketohydrocinnamate; b-Phenylpyruvic acid; β-Phenylpyruvic acid; 3-Phenylpyruvic acid; beta-Phenylpyruvate; Keto-phenylpyruvate; Phenylpyroracemate; Phenylpyruvic acid; b-Phenylpyruvate; 3-PHENYLPYRUVate; β-Phenylpyruvate; Phenylpyruvate; FEMA 3892; Phenylpyruvic acid; Phenylpyruvic acid; Phenylpyruvate
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:30851
- KEGG: C00166
- KEGGdrug: D91915
- PubChem: 997
- HMDB: HMDB0000205
- Metlin: METLIN328
- DrugBank: DB03884
- ChEMBL: CHEMBL1162488
- Wikipedia: Phenylpyruvic_acid
- MetaCyc: PHENYL-PYRUVATE
- KNApSAcK: C00000751
- foodb: FDB008272
- chemspider: 972
- CAS: 156-06-9
- MoNA: PS038801
- MoNA: PS038807
- MoNA: PS038808
- PMhub: MS000000995
- ChEBI: CHEBI:18005
- PubChem: 3466
- PDB-CCD: PPY
- 3DMET: B00048
- NIKKAJI: J11.025F
- RefMet: Phenylpyruvic acid
- medchemexpress: HY-W012530
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-618
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-941
- KNApSAcK: 18005
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
513 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(6)
- phenylalanine degradation:
L-glutamate + phenylpyruvate ⟶ α-ketoglutarate + L-phenylalanine - superpathway of phenylalanine, tyrosine and tryptophan biosynthesis:
L-serine + indole ⟶ H2O + L-tryptophan - phenylalanine biosynthesis:
L-glutamate + phenylpyruvate ⟶ α-ketoglutarate + L-phenylalanine - tryptophan degradation:
α-ketoglutarate + L-tryptophan ⟶ L-glutamate + indolepyruvate - superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis:
4-hydroxyphenylpyruvate + L-glutamate ⟶ 2-oxoglutarate + L-tyrosine - phenylalanine biosynthesis I:
L-glutamate + phenylpyruvate ⟶ 2-oxoglutarate + L-phenylalanine
WikiPathways(0)
Plant Reactome(484)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
prephenate ⟶ H2O + carbon dioxide + phenylpyruvate - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid biosynthesis:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
prephenate ⟶ H2O + carbon dioxide + phenylpyruvate - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid biosynthesis:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid biosynthesis:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid metabolism:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Amino acid biosynthesis:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Phenylalanine biosynthesis I:
prephenate ⟶ H2O + carbon dioxide + phenylpyruvate - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Amino acid metabolism:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Amino acid biosynthesis:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
phenylpyruvate ⟶ Phenylacetaldehyde + carbon dioxide - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid metabolism:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
H2O + L-Asn ⟶ L-Asp + ammonia - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
2OG + L-Val ⟶ Glu + KIV - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
phenylpyruvate ⟶ Phenylacetaldehyde + carbon dioxide - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
H2O + L-Asn ⟶ L-Asp + ammonia - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
H2O + L-Asn ⟶ L-Asp + ammonia - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
L-Phe + PYR ⟶ L-Ala + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid metabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + KIV + NAD ⟶ ISB-CoA + NADH + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
2OG + L-Val ⟶ Glu + KIV - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate - Amino acid biosynthesis:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Phenylalanine biosynthesis I:
L-Glu + phenylpyruvate ⟶ 2OG + L-Phe - Amino acid catabolism:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Ehrlich pathway:
2OG + L-Phe ⟶ L-Glu + phenylpyruvate
INOH(3)
- Phenylalanine degradation ( Phenylalanine degradation ):
H2O + O2 + Phenyl-ethylamine ⟶ H2O2 + NH3 + Phenyl-acetaldehyde - 2-Oxo-glutaric acid + L-Phenylalanine = L-Glutamic acid + Phenyl-pyruvic acid ( Phenylalanine degradation ):
2-Oxo-glutaric acid + L-Phenylalanine ⟶ L-Glutamic acid + Phenyl-pyruvic acid - 2-Oxo-glutaric acid + L-Phenylalanine = L-Glutamic acid + Phenyl-pyruvic acid ( Phenylalanine degradation ):
L-Glutamic acid + Phenyl-pyruvic acid ⟶ 2-Oxo-glutaric acid + L-Phenylalanine
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(20)
- Phenylalanine Metabolism:
2-Oxo-3-phenylpropanoic acid (Mixture oxo and keto) + L-Alanine ⟶ L-Phenylalanine + Pyruvic acid - Phenylalanine Metabolism:
2-Oxo-3-phenylpropanoic acid (Mixture oxo and keto) + L-Tyrosine ⟶ 4-Hydroxyphenylpyruvic acid + L-Phenylalanine - Phenylalanine Biosynthesis:
L-Glutamic acid + Phenylpyruvic acid ⟶ L-Phenylalanine + Oxoglutaric acid - Phenylalanine Metabolism:
Ammonia + Cytochrome c-552 + Phenylpyruvic acid ⟶ Cytochrome c-552 + D-phenylalanine + Water - Phenylalanine Biosynthesis:
L-Glutamic acid + Phenylpyruvic acid ⟶ L-Phenylalanine + Oxoglutaric acid - Phenylalanine and Tyrosine Metabolism:
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Phenylketonuria:
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Tyrosinemia Type 2 (or Richner-Hanhart Syndrome):
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Tyrosinemia Type 3 (TYRO3):
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Tryptophan Metabolism:
N'-Formylkynurenine + Water ⟶ Formic acid + Hydrogen Ion + L-Kynurenine - Tropane, Piperidine, and Pyridine Alkaloid Biosynthesis:
Hydrogen Ion + N-Methylputrescine + Oxygen ⟶ 1-Methylpyrrolinium + Ammonia + Hydrogen peroxide - Phenylalanine and Tyrosine Metabolism:
Adenosine triphosphate + L-Tyrosine ⟶ Adenosine monophosphate + Pyrophosphate - Tyrosinemia Type 3 (TYRO3):
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Tyrosinemia Type 2 (or Richner-Hanhart Syndrome):
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Phenylketonuria:
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Phenylalanine and Tyrosine Metabolism:
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Phenylalanine and Tyrosine Metabolism:
Adenosine triphosphate + L-Phenylalanine ⟶ Adenosine monophosphate + Pyrophosphate - Tyrosinemia Type 3 (TYRO3):
Adenosine triphosphate + L-Tyrosine ⟶ Adenosine monophosphate + Pyrophosphate - Tyrosinemia Type 2 (or Richner-Hanhart Syndrome):
Adenosine triphosphate + L-Tyrosine ⟶ Adenosine monophosphate + Pyrophosphate - Phenylketonuria:
Adenosine triphosphate + L-Tyrosine ⟶ Adenosine monophosphate + Pyrophosphate
PharmGKB(0)
6 个相关的物种来源信息
- 1080010 - Aloe africana: 10.1021/JF071110T
- 3702 - Arabidopsis thaliana:
- 6669 - Daphnia pulex: 10.1038/SREP25125
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 5691 - Trypanosoma brucei:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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BMC plant biology.
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