Benzo[k]tetraphene (BioDeep_00001873637)

Main id: BioDeep_00000009828

 


代谢物信息卡片


1,2:5,6-Dibenzanthracene

化学式: C22H14 (278.1095)
中文名称: 二苯并(a,h)蒽标准溶液
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12=CC=CC=C1C3=CC(C=CC4=CC=CC=C45)=C5C=C3C=C2
InChI: InChI=1S/C22H14/c1-3-7-19-15(5-1)9-11-17-14-22-18(13-21(17)19)12-10-16-6-2-4-8-20(16)22/h1-14H

描述信息

D009676 - Noxae > D002273 - Carcinogens
Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms[1][2].

同义名列表

6 个代谢物同义名

1,2:5,6-Dibenzanthracene; Dibenz[a,h]anthracene; Benzo[k]tetraphene; DBA; 1,2,5,6-Dibenzanthracene; Dibenz[a,h]anthracene



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AHR, AHRR, ALB, CAT, CYP1A1, HPGDS, MYD88, NFE2L2, NR1I3, PFDN5, TLR2, TP53
Peripheral membrane protein 2 CYP1A1, CYP1B1
Endosome membrane 1 MYD88
Endoplasmic reticulum membrane 3 CYP1A1, CYP1A2, CYP1B1
Nucleus 9 AHR, AHRR, ALB, ARID3B, MYD88, NFE2L2, NR1I3, PFDN5, TP53
cytosol 10 AHR, AHRR, ALB, CAT, HPGDS, MYD88, NFE2L2, NR1I3, PFDN5, TP53
centrosome 3 ALB, NFE2L2, TP53
nucleoplasm 7 AHR, AHRR, ARID3B, HPGDS, NFE2L2, NR1I3, TP53
RNA polymerase II transcription regulator complex 1 NFE2L2
Cell membrane 1 TNF
Multi-pass membrane protein 1 SLC45A2
cell surface 3 MYD88, TLR2, TNF
Golgi apparatus 3 ALB, NFE2L2, TLR2
mitochondrial inner membrane 1 CYP1A1
neuronal cell body 1 TNF
Cytoplasm, cytosol 1 NFE2L2
plasma membrane 4 MYD88, NFE2L2, TLR2, TNF
Membrane 5 CAT, CYP1B1, SLC45A2, TLR2, TP53
extracellular exosome 2 ALB, CAT
endoplasmic reticulum 2 ALB, TP53
extracellular space 3 ALB, CPA6, TNF
mitochondrion 4 CAT, CYP1A1, CYP1B1, TP53
protein-containing complex 5 AHR, ALB, CAT, MYD88, TP53
intracellular membrane-bounded organelle 5 CAT, CYP1A1, CYP1A2, CYP1B1, HPGDS
Microsome membrane 3 CYP1A1, CYP1A2, CYP1B1
Single-pass type I membrane protein 1 TLR2
Secreted 1 ALB
extracellular region 3 ALB, CAT, TNF
Mitochondrion matrix 1 TP53
mitochondrial matrix 2 CAT, TP53
anchoring junction 1 ALB
transcription regulator complex 2 AHR, TP53
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 CPA6
nucleolus 1 TP53
Melanosome membrane 1 SLC45A2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 2 TLR2, TNF
Cytoplasm, cytoskeleton 2 NR1I3, TP53
focal adhesion 1 CAT
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Nucleus, PML body 1 TP53
PML body 1 TP53
receptor complex 1 TLR2
ciliary basal body 1 ALB
chromatin 5 AHR, AHRR, NFE2L2, NR1I3, TP53
mediator complex 1 NFE2L2
Cytoplasmic vesicle, phagosome membrane 1 TLR2
cell projection 1 TLR2
phagocytic cup 1 TNF
phagocytic vesicle membrane 1 TLR2
cytoskeleton 1 NR1I3
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
site of double-strand break 1 TP53
aryl hydrocarbon receptor complex 2 AHR, AHRR
cell body 1 TLR2
germ cell nucleus 1 TP53
replication fork 1 TP53
intermediate filament cytoskeleton 1 PFDN5
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
secretory granule membrane 1 TLR2
endoplasmic reticulum lumen 1 ALB
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
platelet alpha granule lumen 1 ALB
[Isoform 1]: Nucleus 1 TP53
extrinsic component of cytoplasmic side of plasma membrane 1 MYD88
prefoldin complex 1 PFDN5
protein-DNA complex 1 NFE2L2
Toll-like receptor 1-Toll-like receptor 2 protein complex 1 TLR2
Toll-like receptor 2-Toll-like receptor 6 protein complex 1 TLR2
extrinsic component of plasma membrane 1 MYD88
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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