L-Threonine phosphate (BioDeep_00001871992)
Main id: BioDeep_00000003159
代谢物信息卡片
threoninium dihydrogen phosphate
化学式: C4H10NO6P (199.0246)
中文名称: L-2-氨基-3-羟基丁酸-3-磷酸
谱图信息:
最多检出来源 Homo sapiens(blood) 86.05%
分子结构信息
SMILES: CC(C(C(=O)O)N)OP(=O)(O)O
InChI: InChI=1S/C4H10NO6P/c1-2(3(5)4(6)7)11-12(8,9)10/h2-3H,5H2,1H3,(H,6,7)(H2,8,9,10)/t2-,3+/m1/s1
描述信息
A L-threonine derivative phosphorylated at the side-chain hydroxy function.
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:190018
- ChEBI: CHEBI:37525
- KEGG: C12147
- PubChem: 3246323
- MeSH: Phosphothreonine
- CAS: 1114-81-4
- MetaboLights: MTBLC37525
- PubChem: 14294
- PDB-CCD: TPO
- 3DMET: B04438
- NIKKAJI: J203.332A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Min Chen, Lan Ni, Jing Chen, Manman Sun, Caihua Qin, Gang Zhang, Aying Zhang, Mingyi Jiang. Rice calcium/calmodulin-dependent protein kinase directly phosphorylates a mitogen-activated protein kinase kinase to regulate abscisic acid responses.
The Plant cell.
2021 07; 33(5):1790-1812. doi:
10.1093/plcell/koab071. [PMID: 33630095] - Jie Yang, Hang He, Yuming He, Qiaozhen Zheng, Qingzhong Li, Xin Feng, Pengcheng Wang, Guocheng Qin, Yangtao Gu, Ping Wu, Chao Peng, Shilei Sun, Yi Zhang, Mingzhang Wen, Rong Chen, Yang Zhao, Tongda Xu. TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America.
2021 06; 118(24):. doi:
10.1073/pnas.2102544118. [PMID: 34099554] - Jianfang Li, Huapeng Zhou, Yan Zhang, Zhen Li, Yongqing Yang, Yan Guo. The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana.
Developmental cell.
2020 11; 55(3):367-380.e6. doi:
10.1016/j.devcel.2020.08.005. [PMID: 32891194] - Xiaoli Zhang, Luis R Flores, Michael C Keeling, Kristina Sliogeryte, Núria Gavara. Ezrin Phosphorylation at T567 Modulates Cell Migration, Mechanical Properties, and Cytoskeletal Organization.
International journal of molecular sciences.
2020 Jan; 21(2):. doi:
10.3390/ijms21020435. [PMID: 31936668] - Andrea Trotta, Azfar Ali Bajwa, Ilaria Mancini, Virpi Paakkarinen, Mathias Pribil, Eva-Mari Aro. The Role of Phosphorylation Dynamics of CURVATURE THYLAKOID 1B in Plant Thylakoid Membranes.
Plant physiology.
2019 12; 181(4):1615-1631. doi:
10.1104/pp.19.00942. [PMID: 31615849] - Xin Zhou, Lan Ni, Yaqin Liu, Mingyi Jiang. Phosphorylation of bip130 by OsMPK1 regulates abscisic acid-induced antioxidant defense in rice.
Biochemical and biophysical research communications.
2019 06; 514(3):750-755. doi:
10.1016/j.bbrc.2019.04.183. [PMID: 31078272] - Geneviève Hamel-Côté, Fanny Lapointe, Daniel Gendron, Marek Rola-Pleszczynski, Jana Stankova. Regulation of platelet-activating factor-induced interleukin-8 expression by protein tyrosine phosphatase 1B.
Cell communication and signaling : CCS.
2019 03; 17(1):21. doi:
10.1186/s12964-019-0334-6. [PMID: 30832675] - Lidiya P Dubytska, Ronald L Thune. Edwardsiella ictaluri type III secretion system (T3SS) effector EseN is a phosphothreonine lyase that inactivates ERK1/2.
Diseases of aquatic organisms.
2018 Sep; 130(2):117-129. doi:
10.3354/dao03255. [PMID: 30198487] - Mohammad A Dallak. Acylated ghrelin induces but deacylated ghrelin prevents hepatic steatosis and insulin resistance in lean rats: Effects on DAG/ PKC/JNK pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Sep; 105(?):299-311. doi:
10.1016/j.biopha.2018.05.098. [PMID: 29860222] - Franck Anicet Ditengou, Dulceneia Gomes, Hugues Nziengui, Philip Kochersperger, Hanna Lasok, Violante Medeiros, Ivan A Paponov, Szilvia Krisztina Nagy, Tímea Virág Nádai, Tamás Mészáros, Beáta Barnabás, Beata Izabela Ditengou, Katja Rapp, Linlin Qi, Xugang Li, Claude Becker, Chuanyou Li, Róbert Dóczi, Klaus Palme. Characterization of auxin transporter PIN6 plasma membrane targeting reveals a function for PIN6 in plant bolting.
The New phytologist.
2018 03; 217(4):1610-1624. doi:
10.1111/nph.14923. [PMID: 29218850] - Franziska Hempel, Irene Stenzel, Mareike Heilmann, Praveen Krishnamoorthy, Wilhelm Menzel, Ralph Golbik, Stefan Helm, Dirk Dobritzsch, Sacha Baginsky, Justin Lee, Wolfgang Hoehenwarter, Ingo Heilmann. MAPKs Influence Pollen Tube Growth by Controlling the Formation of Phosphatidylinositol 4,5-Bisphosphate in an Apical Plasma Membrane Domain.
The Plant cell.
2017 12; 29(12):3030-3050. doi:
10.1105/tpc.17.00543. [PMID: 29167320] - Yoshihisa Ueno, Akane Matsushita, Haruhiko Inoue, Riichiro Yoshida, Chang-Jie Jiang, Hiroshi Takatsuji. WRKY45 phosphorylation at threonine 266 acts negatively on WRKY45-dependent blast resistance in rice.
Plant signaling & behavior.
2017 08; 12(8):e1356968. doi:
10.1080/15592324.2017.1356968. [PMID: 28758876] - Mengmeng Zhu, Tong Zhang, Wei Ji, Cecilia Silva-Sanchez, Wen-Yuan Song, Sarah M Assmann, Alice C Harmon, Sixue Chen. Redox regulation of a guard cell SNF1-related protein kinase in Brassica napus, an oilseed crop.
The Biochemical journal.
2017 07; 474(15):2585-2599. doi:
10.1042/bcj20170070. [PMID: 28642254] - Yosuke Toda, Yin Wang, Akira Takahashi, Yuya Kawai, Yasuomi Tada, Naoki Yamaji, Jian Feng Ma, Motoyuki Ashikari, Toshinori Kinoshita. Oryza sativa H+-ATPase (OSA) is Involved in the Regulation of Dumbbell-Shaped Guard Cells of Rice.
Plant & cell physiology.
2016 Jun; 57(6):1220-30. doi:
10.1093/pcp/pcw070. [PMID: 27048369] - Marta Cifuentes, Sylvie Jolivet, Laurence Cromer, Hirofumi Harashima, Petra Bulankova, Charlotte Renne, Wayne Crismani, Yuko Nomura, Hirofumi Nakagami, Keiko Sugimoto, Arp Schnittger, Karel Riha, Raphael Mercier. TDM1 Regulation Determines the Number of Meiotic Divisions.
PLoS genetics.
2016 Feb; 12(2):e1005856. doi:
10.1371/journal.pgen.1005856. [PMID: 26871453] - DongHyuk Lee, Gildas Bourdais, Gang Yu, Silke Robatzek, Gitta Coaker. Phosphorylation of the Plant Immune Regulator RPM1-INTERACTING PROTEIN4 Enhances Plant Plasma Membrane H⁺-ATPase Activity and Inhibits Flagellin-Triggered Immune Responses in Arabidopsis.
The Plant cell.
2015 Jul; 27(7):2042-56. doi:
10.1105/tpc.114.132308. [PMID: 26198070] - Euan Parnell, Andreas Koschinski, Manuela Zaccolo, Ryan T Cameron, George S Baillie, Gemma L Baillie, Alison Porter, Stuart P McElroy, Stephen J Yarwood. Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells.
Biochimica et biophysica acta.
2015 Jul; 1853(7):1749-58. doi:
10.1016/j.bbamcr.2015.04.009. [PMID: 25913012] - Bo Li, Shan Jiang, Xiao Yu, Cheng Cheng, Sixue Chen, Yanbing Cheng, Joshua S Yuan, Daohong Jiang, Ping He, Libo Shan. Phosphorylation of trihelix transcriptional repressor ASR3 by MAP KINASE4 negatively regulates Arabidopsis immunity.
The Plant cell.
2015 Mar; 27(3):839-56. doi:
10.1105/tpc.114.134809. [PMID: 25770109] - Victor Babich, Francesca Di Sole. The Na+/H+ Exchanger-3 (NHE3) Activity Requires Ezrin Binding to Phosphoinositide and Its Phosphorylation.
PloS one.
2015; 10(6):e0129306. doi:
10.1371/journal.pone.0129306. [PMID: 26042733] - E Boex-Fontvieille, M Daventure, M Jossier, M Hodges, M Zivy, G Tcherkez. Phosphorylation pattern of Rubisco activase in Arabidopsis leaves.
Plant biology (Stuttgart, Germany).
2014 May; 16(3):550-7. doi:
10.1111/plb.12100. [PMID: 24119201] - Joanne L Parker, Simon Newstead. Molecular basis of nitrate uptake by the plant nitrate transporter NRT1.1.
Nature.
2014 Mar; 507(7490):68-72. doi:
10.1038/nature13116. [PMID: 24572366] - Ji Sun, John R Bankston, Jian Payandeh, Thomas R Hinds, William N Zagotta, Ning Zheng. Crystal structure of the plant dual-affinity nitrate transporter NRT1.1.
Nature.
2014 Mar; 507(7490):73-7. doi:
10.1038/nature13074. [PMID: 24572362] - Jer-Sheng Lin, Hsin-Hui Wu, Pang-Hung Hsu, Lay-Sun Ma, Yin-Yuin Pang, Ming-Daw Tsai, Erh-Min Lai. Fha interaction with phosphothreonine of TssL activates type VI secretion in Agrobacterium tumefaciens.
PLoS pathogens.
2014 Mar; 10(3):e1003991. doi:
10.1371/journal.ppat.1003991. [PMID: 24626341] - Xiao-Ning Zhang, Cecilia Mo, Wesley M Garrett, Bret Cooper. Phosphothreonine 218 is required for the function of SR45.1 in regulating flower petal development in Arabidopsis.
Plant signaling & behavior.
2014; 9(7):e29134. doi:
10.4161/psb.29134. [PMID: 25763493] - Satoru Machida, Y Adam Yuan. Crystal structure of Arabidopsis thaliana Dawdle forkhead-associated domain reveals a conserved phospho-threonine recognition cleft for dicer-like 1 binding.
Molecular plant.
2013 Jul; 6(4):1290-300. doi:
10.1093/mp/sst007. [PMID: 23313986] - Yoshinori Ban, Yuhko Kobayashi, Tomomi Hara, Takahiro Hamada, Takashi Hashimoto, Shin Takeda, Tsukaho Hattori. α-tubulin is rapidly phosphorylated in response to hyperosmotic stress in rice and Arabidopsis.
Plant & cell physiology.
2013 Jun; 54(6):848-58. doi:
10.1093/pcp/pct065. [PMID: 23628996] - Supachai Topanurak, Joan D Ferraris, Jinxi Li, Yuichiro Izumi, Chester K Williams, Marjan Gucek, Guanghui Wang, Xiaoming Zhou, Maurice B Burg. High NaCl- and urea-induced posttranslational modifications that increase glycerophosphocholine by inhibiting GDPD5 phosphodiesterase.
Proceedings of the National Academy of Sciences of the United States of America.
2013 Apr; 110(18):7482-7. doi:
10.1073/pnas.1305220110. [PMID: 23589856] - Małgorzata Janicka-Russak, Katarzyna Kabała. Abscisic acid and hydrogen peroxide induce modification of plasma membrane H(+)-ATPase from Cucumis sativus L. roots under heat shock.
Journal of plant physiology.
2012 Nov; 169(16):1607-14. doi:
10.1016/j.jplph.2012.05.013. [PMID: 22749287] - Jürgen van Baal, John de Widt, Nullin Divecha, Wim J van Blitterswijk. Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor.
The international journal of biochemistry & cell biology.
2012 Nov; 44(11):1791-9. doi:
10.1016/j.biocel.2012.06.021. [PMID: 22732145] - Rikard Fristedt, Wioleta Wasilewska, Elzbieta Romanowska, Alexander V Vener. Differential phosphorylation of thylakoid proteins in mesophyll and bundle sheath chloroplasts from maize plants grown under low or high light.
Proteomics.
2012 Sep; 12(18):2852-61. doi:
10.1002/pmic.201200196. [PMID: 22833285] - Małgorzata Janicka-Russak, Katarzyna Kabała, Marek Burzynski. Different effect of cadmium and copper on H+-ATPase activity in plasma membrane vesicles from Cucumis sativus roots.
Journal of experimental botany.
2012 Jun; 63(11):4133-42. doi:
10.1093/jxb/ers097. [PMID: 22451724] - John D Mayfield, Anna-Lisa Paul, Robert J Ferl. The 14-3-3 proteins of Arabidopsis regulate root growth and chloroplast development as components of the photosensory system.
Journal of experimental botany.
2012 May; 63(8):3061-70. doi:
10.1093/jxb/ers022. [PMID: 22378945] - Man-Ho Oh, Hyoung Seok Kim, Xia Wu, Steven D Clouse, Raymond E Zielinski, Steven C Huber. Calcium/calmodulin inhibition of the Arabidopsis BRASSINOSTEROID-INSENSITIVE 1 receptor kinase provides a possible link between calcium and brassinosteroid signalling.
The Biochemical journal.
2012 Apr; 443(2):515-23. doi:
10.1042/bj20111871. [PMID: 22309147] - Sébastien Pyr Dit Ruys, Xuemin Wang, Ewan M Smith, Gaëtan Herinckx, Nusrat Hussain, Mark H Rider, Didier Vertommen, Christopher G Proud. Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase.
The Biochemical journal.
2012 Mar; 442(3):681-92. doi:
10.1042/bj20111530. [PMID: 22216903] - Neelja Singhal, Prashant Sharma, Manish Kumar, Beenu Joshi, Deepa Bisht. Analysis of intracellular expressed proteins of Mycobacterium tuberculosis clinical isolates.
Proteome science.
2012 Mar; 10(1):14. doi:
10.1186/1477-5956-10-14. [PMID: 22375954] - Rachana Sainger, Juan B Grau, Paolo Poggio, Emanuela Branchetti, Joseph E Bavaria, Joseph H Gorman, Robert C Gorman, Giovanni Ferrari. Dephosphorylation of circulating human osteopontin correlates with severe valvular calcification in patients with calcific aortic valve disease.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2012 Mar; 17(2):111-8. doi:
10.3109/1354750x.2011.642407. [PMID: 22191734] - Małgorzata Janicka-Russak, Katarzyna Kabała, Anna Wdowikowska, Grażyna Kłobus. Response of plasma membrane H(+)-ATPase to low temperature in cucumber roots.
Journal of plant research.
2012 03; 125(2):291-300. doi:
10.1007/s10265-011-0438-6. [PMID: 21638005] - Yafei Qi, Ute Armbruster, Christian Schmitz-Linneweber, Etienne Delannoy, Andeol Falcon de Longevialle, Thilo Rühle, Ian Small, Peter Jahns, Dario Leister. Arabidopsis CSP41 proteins form multimeric complexes that bind and stabilize distinct plastid transcripts.
Journal of experimental botany.
2012 Feb; 63(3):1251-70. doi:
10.1093/jxb/err347. [PMID: 22090436] - Jessica Schmitz, Mark Aurel Schöttler, Stephan Krueger, Stefan Geimer, Anja Schneider, Tatjana Kleine, Dario Leister, Kirsten Bell, Ulf-Ingo Flügge, Rainer E Häusler. Defects in leaf carbohydrate metabolism compromise acclimation to high light and lead to a high chlorophyll fluorescence phenotype in Arabidopsis thaliana.
BMC plant biology.
2012 Jan; 12(?):8. doi:
10.1186/1471-2229-12-8. [PMID: 22248311] - Mingjia Chen, Hongmei Zeng, Dewen Qiu, Lihua Guo, Xiufen Yang, Huaixing Shi, Tingting Zhou, Jing Zhao. Purification and characterization of a novel hypersensitive response-inducing elicitor from Magnaporthe oryzae that triggers defense response in rice.
PloS one.
2012; 7(5):e37654. doi:
10.1371/journal.pone.0037654. [PMID: 22624059] - Anastasia Liapis, Fannie W Chen, Joanna P Davies, Rong Wang, Yiannis A Ioannou. MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site.
PloS one.
2012; 7(4):e34424. doi:
10.1371/journal.pone.0034424. [PMID: 22514632] - Yan Yang, Zhenyin Shi, Adili Reheman, Joseph W Jin, Conglei Li, Yiming Wang, Marc C Andrews, Pingguo Chen, Guangheng Zhu, Wenhua Ling, Heyu Ni. Plant food delphinidin-3-glucoside significantly inhibits platelet activation and thrombosis: novel protective roles against cardiovascular diseases.
PloS one.
2012; 7(5):e37323. doi:
10.1371/journal.pone.0037323. [PMID: 22624015] - Man-Ho Oh, Steven D Clouse, Steven C Huber. Tyrosine Phosphorylation of the BRI1 Receptor Kinase Occurs via a Post-Translational Modification and is Activated by the Juxtamembrane Domain.
Frontiers in plant science.
2012; 3(?):175. doi:
10.3389/fpls.2012.00175. [PMID: 22891071] - Takeshi Terabayashi, Masaji Sakaguchi, Kaori Shinmyozu, Toshio Ohshima, Ai Johjima, Teru Ogura, Hiroaki Miki, Ryuichi Nishinakamura. Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development.
PloS one.
2012; 7(6):e39714. doi:
10.1371/journal.pone.0039714. [PMID: 22768111] - Stephen S C Chim, Wing S Lee, Yuen H Ting, Oi K Chan, Shara W Y Lee, Tak Y Leung. Systematic identification of spontaneous preterm birth-associated RNA transcripts in maternal plasma.
PloS one.
2012; 7(4):e34328. doi:
10.1371/journal.pone.0034328. [PMID: 22496790] - Hehe Liu, Jiwen Wang, Jianmin Si, Jing Jia, Liang Li, Chunchun Han, Kailiang Huang, Hua He, Feng Xu. Molecular cloning and in silico analysis of the duck (Anas platyrhynchos) MEF2A gene cDNA and its expression profile in muscle tissues during fetal development.
Genetics and molecular biology.
2012 Jan; 35(1):182-90. doi:
10.1590/s1415-47572012005000023. [PMID: 22481893] - Qingtang Shen, Zhou Liu, Fengming Song, Qi Xie, Linda Hanley-Bowdoin, Xueping Zhou. Tomato SlSnRK1 protein interacts with and phosphorylates βC1, a pathogenesis protein encoded by a geminivirus β-satellite.
Plant physiology.
2011 Nov; 157(3):1394-406. doi:
10.1104/pp.111.184648. [PMID: 21885668] - Ewout J Hoorn, Stephen B Walsh, James A McCormick, Antje Fürstenberg, Chao-Ling Yang, Tom Roeschel, Alexander Paliege, Alexander J Howie, James Conley, Sebastian Bachmann, Robert J Unwin, David H Ellison. The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.
Nature medicine.
2011 Oct; 17(10):1304-9. doi:
10.1038/nm.2497. [PMID: 21963515] - Baibaswata Nayak, Vinay K Kondeti, Ping Xie, Sun Lin, Navin Viswakarma, Kirtee Raparia, Yashpal S Kanwar. Transcriptional and post-translational modulation of myo-inositol oxygenase by high glucose and related pathobiological stresses.
The Journal of biological chemistry.
2011 Aug; 286(31):27594-611. doi:
10.1074/jbc.m110.217141. [PMID: 21652700] - Tzong-Yi Lee, Neil Arvin Bretaña, Cheng-Tsung Lu. PlantPhos: using maximal dependence decomposition to identify plant phosphorylation sites with substrate site specificity.
BMC bioinformatics.
2011 Jun; 12(?):261. doi:
10.1186/1471-2105-12-261. [PMID: 21703007] - Anna Zorina, Natalia Stepanchenko, Galina V Novikova, Maria Sinetova, Vladimir B Panichkin, Igor E Moshkov, Vladislav V Zinchenko, Sergey V Shestakov, Iwane Suzuki, Norio Murata, Dmitry A Los. Eukaryotic-like Ser/Thr protein kinases SpkC/F/K are involved in phosphorylation of GroES in the Cyanobacterium synechocystis.
DNA research : an international journal for rapid publication of reports on genes and genomes.
2011 Jun; 18(3):137-51. doi:
10.1093/dnares/dsr006. [PMID: 21551175] - Yan Lu, David A Hall, Robert L Last. A small zinc finger thylakoid protein plays a role in maintenance of photosystem II in Arabidopsis thaliana.
The Plant cell.
2011 May; 23(5):1861-75. doi:
10.1105/tpc.111.085456. [PMID: 21586683] - Riccardo Aiese Cigliano, Walter Sanseverino, Gaetana Cremona, Federica M Consiglio, Clara Conicella. Evolution of parallel spindles like genes in plants and highlight of unique domain architecture#.
BMC evolutionary biology.
2011 Mar; 11(?):78. doi:
10.1186/1471-2148-11-78. [PMID: 21435253] - Morgan Gallazzini, Gary E Heussler, Margarita Kunin, Yuichiro Izumi, Maurice B Burg, Joan D Ferraris. High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization.
Molecular biology of the cell.
2011 Mar; 22(5):703-14. doi:
10.1091/mbc.e10-08-0681. [PMID: 21209322] - Kenny M Gomolplitinant, Milton H Saier. Evolution of the oligopeptide transporter family.
The Journal of membrane biology.
2011 Mar; 240(2):89-110. doi:
10.1007/s00232-011-9347-9. [PMID: 21347612] - Kenji Daigo, Takeshi Kawamura, Yoshihiro Ohta, Riuko Ohashi, Satoshi Katayose, Toshiya Tanaka, Hiroyuki Aburatani, Makoto Naito, Tatsuhiko Kodama, Sigeo Ihara, Takao Hamakubo. Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.
The Journal of biological chemistry.
2011 Jan; 286(1):674-86. doi:
10.1074/jbc.m110.154732. [PMID: 21047794] - Xiaolu Zhao, Ileana R León, Steffen Bak, Martin Mogensen, Krzysztof Wrzesinski, Kurt Højlund, Ole Nørregaard Jensen. Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.
Molecular & cellular proteomics : MCP.
2011 Jan; 10(1):M110.000299. doi:
10.1074/mcp.m110.000299. [PMID: 20833797] - Laurie E Kilpatrick, Stephen W Standage, Haiying Li, Nichelle R Raj, Helen M Korchak, Marla R Wolfson, Clifford S Deutschman. Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC).
Journal of leukocyte biology.
2011 Jan; 89(1):3-10. doi:
10.1189/jlb.0510281. [PMID: 20724665] - Susana Rivas, Stéphane Genin. A plethora of virulence strategies hidden behind nuclear targeting of microbial effectors.
Frontiers in plant science.
2011; 2(?):104. doi:
10.3389/fpls.2011.00104. [PMID: 22639625] - Nina Jaspert, Christian Throm, Claudia Oecking. Arabidopsis 14-3-3 proteins: fascinating and less fascinating aspects.
Frontiers in plant science.
2011; 2(?):96. doi:
10.3389/fpls.2011.00096. [PMID: 22639620] - Protim Sarker, Sultan Ahmed, Snigdha Tiash, Rokeya Sultana Rekha, Roger Stromberg, Jan Andersson, Peter Bergman, Gudmundur H Gudmundsson, Birgitta Agerberth, Rubhana Raqib. Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy.
PloS one.
2011; 6(6):e20637. doi:
10.1371/journal.pone.0020637. [PMID: 21673991] - Rikard Fristedt, Alexander V Vener. High light induced disassembly of photosystem II supercomplexes in Arabidopsis requires STN7-dependent phosphorylation of CP29.
PloS one.
2011; 6(9):e24565. doi:
10.1371/journal.pone.0024565. [PMID: 21915352] - Hanief M Shahjee, Kristopher R Koch, Li Guo, Chen-Ou Zhang, Susan K Keay. Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells.
Journal of experimental & clinical cancer research : CR.
2010 Dec; 29(?):160. doi:
10.1186/1756-9966-29-160. [PMID: 21143984] - Katarzyna Kabała, Małgorzata Janicka-Russak, Grazyna Kłobus. Different responses of tonoplast proton pumps in cucumber roots to cadmium and copper.
Journal of plant physiology.
2010 Nov; 167(16):1328-35. doi:
10.1016/j.jplph.2010.03.020. [PMID: 20696494] - Nicola J Beresford, Charis Saville, Hayley J Bennett, Ian S Roberts, Lydia Tabernero. A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis.
BMC genomics.
2010 Aug; 11(?):457. doi:
10.1186/1471-2164-11-457. [PMID: 20678187] - Jeroen Declercq, Anujith Kumar, Janna A Van Diepen, Irene O C M Vroegrijk, Conny Gysemans, Caterina Di Pietro, Peter J Voshol, Chantal Mathieu, Nadine Ectors, Wim J M Van de Ven, Catherine M Verfaillie. Increased beta-cell mass by islet transplantation and PLAG1 overexpression causes hyperinsulinemic normoglycemia and hepatic insulin resistance in mice.
Diabetes.
2010 Aug; 59(8):1957-65. doi:
10.2337/db09-1446. [PMID: 20522588] - Rikard Fristedt, Pontus Granath, Alexander V Vener. A protein phosphorylation threshold for functional stacking of plant photosynthetic membranes.
PloS one.
2010 Jun; 5(6):e10963. doi:
10.1371/journal.pone.0010963. [PMID: 20532038] - Adam Moolna, Caroline G Bowsher. The physiological importance of photosynthetic ferredoxin NADP+ oxidoreductase (FNR) isoforms in wheat.
Journal of experimental botany.
2010 Jun; 61(10):2669-81. doi:
10.1093/jxb/erq101. [PMID: 20410318] - Lan Yin, Björn Lundin, Martine Bertrand, Markus Nurmi, Katalin Solymosi, Saijaliisa Kangasjärvi, Eva-Mari Aro, Benoît Schoefs, Cornelia Spetea. Role of thylakoid ATP/ADP carrier in photoinhibition and photoprotection of photosystem II in Arabidopsis.
Plant physiology.
2010 Jun; 153(2):666-77. doi:
10.1104/pp.110.155804. [PMID: 20357135] - Claudia Sa E Cunha, Natalie J Griffiths, Mumtaz Virji. Neisseria meningitidis Opc invasin binds to the sulphated tyrosines of activated vitronectin to attach to and invade human brain endothelial cells.
PLoS pathogens.
2010 May; 6(5):e1000911. doi:
10.1371/journal.ppat.1000911. [PMID: 20502634] - Faridoon K Yousafzai, Nadia Al-Kaff, Graham Moore. Structural and functional relationship between the Ph1 locus protein 5B2 in wheat and CDK2 in mammals.
Functional & integrative genomics.
2010 May; 10(2):157-66. doi:
10.1007/s10142-010-0170-7. [PMID: 20422243] - Kiran Mahajan, Domenico Coppola, Sridevi Challa, Bin Fang, Y Ann Chen, Weiwei Zhu, Alexis S Lopez, John Koomen, Robert W Engelman, Charlene Rivera, Rebecca S Muraoka-Cook, Jin Q Cheng, Ernst Schönbrunn, Said M Sebti, H Shelton Earp, Nupam P Mahajan. Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation.
PloS one.
2010 Mar; 5(3):e9646. doi:
10.1371/journal.pone.0009646. [PMID: 20333297] - Kun-Ming Chen, Maija Holmström, Wuttinun Raksajit, Marjaana Suorsa, Mirva Piippo, Eva-Mari Aro. Small chloroplast-targeted DnaJ proteins are involved in optimization of photosynthetic reactions in Arabidopsis thaliana.
BMC plant biology.
2010 Mar; 10(?):43. doi:
10.1186/1471-2229-10-43. [PMID: 20205940] - K Mutig, T Saritas, S Uchida, T Kahl, T Borowski, A Paliege, A Böhlick, M Bleich, Q Shan, S Bachmann. Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation.
American journal of physiology. Renal physiology.
2010 Mar; 298(3):F502-9. doi:
10.1152/ajprenal.00476.2009. [PMID: 20007345] - Akira Ikari, Keishi Kinjo, Kosuke Atomi, Yohei Sasaki, Yasuhiro Yamazaki, Junko Sugatani. Extracellular Mg(2+) regulates the tight junctional localization of claudin-16 mediated by ERK-dependent phosphorylation.
Biochimica et biophysica acta.
2010 Mar; 1798(3):415-21. doi:
10.1016/j.bbamem.2009.11.005. [PMID: 19914201] - Chang-Cai Liu, Tian-Cong Lu, Hua-Hua Li, Hong-Xia Wang, Gui-Feng Liu, Ling Ma, Chuan-Ping Yang, Bai-Chen Wang. Phosphoproteomic identification and phylogenetic analysis of ribosomal P-proteins in Populus dormant terminal buds.
Planta.
2010 Feb; 231(3):571-81. doi:
10.1007/s00425-009-1037-9. [PMID: 20072825] - Bart Baan, Gerard C M van der Zon, J Antonie Maassen, D Margriet Ouwens. The nuclear appearance of ERK1/2 and p38 determines the sequential induction of ATF2-Thr71 and ATF2-Thr69 phosphorylation by serum in JNK-deficient cells.
Molecular and cellular endocrinology.
2009 Nov; 311(1-2):94-100. doi:
10.1016/j.mce.2009.07.023. [PMID: 19647037] - Christian Hansen, Jillian Howlin, Anders Tengholm, Oleg Dyachok, Wolfgang F Vogel, Angus C Nairn, Paul Greengard, Tommy Andersson. Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
The Journal of biological chemistry.
2009 Oct; 284(40):27533-43. doi:
10.1074/jbc.m109.048884. [PMID: 19651774] - Stella Tournaviti, Enrica San Pietro, Stefan Terjung, Tobias Schafmeier, Sabine Wegehingel, Julia Ritzerfeld, Juliane Schulz, Deborah F Smith, Rainer Pepperkok, Walter Nickel. Reversible phosphorylation as a molecular switch to regulate plasma membrane targeting of acylated SH4 domain proteins.
Traffic (Copenhagen, Denmark).
2009 Aug; 10(8):1047-60. doi:
10.1111/j.1600-0854.2009.00921.x. [PMID: 19453972] - Mercedes Martín, Helena T Funk, Patricia H Serrot, Peter Poltnigg, Bartolomé Sabater. Functional characterization of the thylakoid Ndh complex phosphorylation by site-directed mutations in the ndhF gene.
Biochimica et biophysica acta.
2009 Jul; 1787(7):920-8. doi:
10.1016/j.bbabio.2009.03.001. [PMID: 19272354] - Wei Shen, Maria Ines Reyes, Linda Hanley-Bowdoin. Arabidopsis protein kinases GRIK1 and GRIK2 specifically activate SnRK1 by phosphorylating its activation loop.
Plant physiology.
2009 Jun; 150(2):996-1005. doi:
10.1104/pp.108.132787. [PMID: 19339507] - Dor Salomon, Arale Bonshtien, Maya Mayrose, Chao Zhang, Kevan M Shokat, Guido Sessa. Bypassing kinase activity of the tomato Pto resistance protein with small molecule ligands.
The Journal of biological chemistry.
2009 May; 284(22):15289-98. doi:
10.1074/jbc.m809724200. [PMID: 19332544] - Ravikant Ranjan, Anwar Ahmed, Samudrala Gourinath, Pushkar Sharma. Dissection of mechanisms involved in the regulation of Plasmodium falciparum calcium-dependent protein kinase 4.
The Journal of biological chemistry.
2009 May; 284(22):15267-76. doi:
10.1074/jbc.m900656200. [PMID: 19307175] - Elena Sotillo, Judit Garriga, Amol Padgaonkar, Alison Kurimchak, Jeanette Gowen Cook, Xavier Graña. Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E.
The Journal of biological chemistry.
2009 May; 284(21):14126-35. doi:
10.1074/jbc.m900687200. [PMID: 19321444] - Simon E Kolstoe, Basil H Ridha, Vittorio Bellotti, Nan Wang, Carol V Robinson, Sebastian J Crutch, Geoffrey Keir, Riitta Kukkastenvehmas, J Ruth Gallimore, Winston L Hutchinson, Philip N Hawkins, Stephen P Wood, Martin N Rossor, Mark B Pepys. Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.
Proceedings of the National Academy of Sciences of the United States of America.
2009 May; 106(18):7619-23. doi:
10.1073/pnas.0902640106. [PMID: 19372378] - Peter Max Gehrig, Bernd Roschitzki, Dorothea Rutishauser, Sonja Reiland, Ralph Schlapbach. Phosphorylated serine and threonine residues promote site-specific fragmentation of singly charged, arginine-containing peptide ions.
Rapid communications in mass spectrometry : RCM.
2009 May; 23(10):1435-45. doi:
10.1002/rcm.4019. [PMID: 19353557] - Joshua E Kiss, Xin Gao, Joseph M Krepp, John M Hawdon. Interaction of hookworm 14-3-3 with the forkhead transcription factor DAF-16 requires intact Akt phosphorylation sites.
Parasites & vectors.
2009 Apr; 2(1):21. doi:
10.1186/1756-3305-2-21. [PMID: 19393088] - Ram Samudrala, Fred Heffron, Jason E McDermott. Accurate prediction of secreted substrates and identification of a conserved putative secretion signal for type III secretion systems.
PLoS pathogens.
2009 Apr; 5(4):e1000375. doi:
10.1371/journal.ppat.1000375. [PMID: 19390620] - Brian H Kvitko, Duck Hwan Park, André C Velásquez, Chia-Fong Wei, Alistair B Russell, Gregory B Martin, David J Schneider, Alan Collmer. Deletions in the repertoire of Pseudomonas syringae pv. tomato DC3000 type III secretion effector genes reveal functional overlap among effectors.
PLoS pathogens.
2009 Apr; 5(4):e1000388. doi:
10.1371/journal.ppat.1000388. [PMID: 19381254] - Henri S Saleh, Ulrike Merkel, Katja J Geissler, Tobias Sperka, Antonio Sechi, Constanze Breithaupt, Helen Morrison. Properties of an ezrin mutant defective in F-actin binding.
Journal of molecular biology.
2009 Jan; 385(4):1015-31. doi:
10.1016/j.jmb.2008.11.051. [PMID: 19084535] - Chun-Chi Lin, Yu-San Huoh, Karl R Schmitz, Liselotte E Jensen, Kathryn M Ferguson. Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.
Structure (London, England : 1993).
2008 Dec; 16(12):1806-16. doi:
10.1016/j.str.2008.09.011. [PMID: 19081057] - Anchalee Chaidee, Chatchawal Wongchai, Wolfgang Pfeiffer. Extracellular alkaline phosphatase is a sensitive marker for cellular stimulation and exocytosis in heterotroph cell cultures of Chenopodium rubrum.
Journal of plant physiology.
2008 Nov; 165(16):1655-66. doi:
10.1016/j.jplph.2007.12.012. [PMID: 18433930] - Laia Vilà, Núria Roglans, Marta Alegret, Rosa María Sánchez, Manuel Vázquez-Carrera, Juan Carlos Laguna. Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism.
Hepatology (Baltimore, Md.).
2008 Nov; 48(5):1506-16. doi:
10.1002/hep.22523. [PMID: 18924245] - Ping-Chih Ho, Pawan Gupta, Yao-Chen Tsui, Sung Gil Ha, Mostaqul Huq, Li-Na Wei. Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation.
Cellular signalling.
2008 Oct; 20(10):1911-9. doi:
10.1016/j.cellsig.2008.07.001. [PMID: 18655826] - Tine E Thingholm, Martin R Larsen, Christian R Ingrell, Moustapha Kassem, Ole N Jensen. TiO(2)-based phosphoproteomic analysis of the plasma membrane and the effects of phosphatase inhibitor treatment.
Journal of proteome research.
2008 Aug; 7(8):3304-13. doi:
10.1021/pr800099y. [PMID: 18578522] - Wimolpak Sriwai, Huiping Zhou, Karnam S Murthy. G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA.
The Biochemical journal.
2008 May; 411(3):543-51. doi:
10.1042/bj20071299. [PMID: 18237278] - Lucia C Strader, Melanie Monroe-Augustus, Bonnie Bartel. The IBR5 phosphatase promotes Arabidopsis auxin responses through a novel mechanism distinct from TIR1-mediated repressor degradation.
BMC plant biology.
2008 Apr; 8(?):41. doi:
10.1186/1471-2229-8-41. [PMID: 18423007] - D Cozzone, S Fröjdö, E Disse, C Debard, M Laville, L Pirola, H Vidal. Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients.
Diabetologia.
2008 Mar; 51(3):512-21. doi:
10.1007/s00125-007-0913-8. [PMID: 18204829] - Anna Ihnatowicz, Paolo Pesaresi, Katharina Lohrig, Dirk Wolters, Bernd Müller, Dario Leister. Impaired photosystem I oxidation induces STN7-dependent phosphorylation of the light-harvesting complex I protein Lhca4 in Arabidopsis thaliana.
Planta.
2008 Feb; 227(3):717-22. doi:
10.1007/s00425-007-0650-8. [PMID: 17968587]
