4-aminoimidazole (BioDeep_00001869482)

Main id: BioDeep_00000005752

 


代谢物信息卡片


4-aminoimidazole

化学式: C3H5N3 (83.0483)
中文名称: 4-氨基咪唑
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(NC=N1)N
InChI: InChI=1S/C3H5N3/c4-3-1-5-2-6-3/h1-2H,4H2,(H,5,6)

描述信息

同义名列表

2 个代谢物同义名

4-aminoimidazole; 5-Aminoimidazole



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 AKT1, FBP1, FOXO1, IRS1, NR0B2, PCK1, PRKAA1, PRKAA2, SQSTM1, ULK1
Endosome membrane 1 INSR
Endoplasmic reticulum membrane 2 G6PC3, ULK1
Cytoplasmic vesicle, autophagosome 1 SQSTM1
Nucleus 10 AKT1, FBP1, FOXO1, IRS1, NR0B2, PPARGC1A, PRKAA1, PRKAA2, RFC2, SQSTM1
autophagosome 3 MAP1LC3A, SQSTM1, ULK1
cytosol 14 ACACA, ADSL, AKT1, DCTN5, FBP1, FOXO1, IRS1, MAP1LC3A, PCK1, PPARGC1A, PRKAA1, PRKAA2, SQSTM1, ULK1
dendrite 2 PRKAA1, PRKAA2
centrosome 1 DCTN5
nucleoplasm 10 AKT1, DCTN5, FOXO1, IRS1, NR0B2, PPARGC1A, PRKAA1, PRKAA2, RFC2, SQSTM1
Cell membrane 3 AKT1, INSR, SLC5A2
Lipid-anchor 1 MAP1LC3A
lamellipodium 1 AKT1
Multi-pass membrane protein 2 G6PC3, SLC5A2
cell cortex 1 AKT1
glutamatergic synapse 3 AKT1, MAP1LC3A, SQSTM1
Golgi apparatus 1 PRKAA2
Golgi membrane 1 INS
neuronal cell body 2 PRKAA1, PRKAA2
postsynapse 1 AKT1
Cytoplasm, cytosol 4 ACACA, PCK1, SQSTM1, ULK1
Lysosome 2 INSR, SQSTM1
plasma membrane 4 AKT1, INSR, IRS1, SLC5A2
Membrane 5 AKT1, G6PC3, INSR, PRKAA2, SLC5A2
apical plasma membrane 2 PRKAA1, SLC5A2
axon 4 INSR, PRKAA1, PRKAA2, ULK1
caveola 2 INSR, IRS1
extracellular exosome 5 FBP1, INSR, PCK1, SLC5A2, SQSTM1
endoplasmic reticulum 3 G6PC3, PCK1, SQSTM1
extracellular space 1 INS
mitochondrion 3 ACACA, FOXO1, SQSTM1
protein-containing complex 3 ADSL, AKT1, NR0B2
intracellular membrane-bounded organelle 4 IRS1, MAP1LC3A, NR0B2, SQSTM1
Single-pass type I membrane protein 1 INSR
Secreted 1 INS
extracellular region 1 INS
mitochondrial outer membrane 1 ULK1
neuronal cell body membrane 1 INSR
nuclear membrane 1 DCTN5
external side of plasma membrane 1 INSR
actin cytoskeleton 1 ACACA
cytoplasmic vesicle 1 SQSTM1
microtubule cytoskeleton 1 AKT1
P-body 1 SQSTM1
cell-cell junction 1 AKT1
recycling endosome 1 ULK1
vesicle 1 AKT1
Apical cell membrane 1 SLC5A2
Cytoplasm, cytoskeleton 2 DCTN5, MAP1LC3A
microtubule 1 MAP1LC3A
spindle 1 AKT1
Nucleus, PML body 2 PPARGC1A, SQSTM1
PML body 2 PPARGC1A, SQSTM1
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
nuclear speck 2 PRKAA1, PRKAA2
Cytoplasm, myofibril, sarcomere 1 SQSTM1
Late endosome 3 INSR, MAP1LC3A, SQSTM1
sarcomere 1 SQSTM1
receptor complex 1 INSR
ciliary basal body 1 AKT1
chromatin 4 FOXO1, NR0B2, PPARGC1A, PRKAA1
Cytoplasmic vesicle, autophagosome membrane 1 MAP1LC3A
autophagosome membrane 2 MAP1LC3A, ULK1
sperm midpiece 1 SQSTM1
organelle membrane 1 MAP1LC3A
fibrillar center 1 ACACA
Endomembrane system 1 MAP1LC3A
endosome lumen 1 INS
Chromosome, centromere, kinetochore 1 DCTN5
phagophore assembly site 2 SQSTM1, ULK1
phagophore assembly site membrane 1 ULK1
cytoplasmic stress granule 1 PRKAA2
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 1 INS
dynactin complex 1 DCTN5
kinetochore 1 DCTN5
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
aggresome 1 SQSTM1
[Isoform 1]: Nucleus 1 PPARGC1A
intracellular non-membrane-bounded organelle 1 SQSTM1
dendrite membrane 1 INSR
nucleotide-activated protein kinase complex 2 PRKAA1, PRKAA2
Lewy body 1 SQSTM1
Preautophagosomal structure 2 SQSTM1, ULK1
Atg1/ULK1 kinase complex 1 ULK1
omegasome membrane 1 ULK1
Autolysosome 2 MAP1LC3A, SQSTM1
inclusion body 1 SQSTM1
insulin receptor complex 2 INSR, IRS1
Ctf18 RFC-like complex 1 RFC2
DNA replication factor C complex 1 RFC2
amphisome 1 SQSTM1
[Isoform B4]: Nucleus 1 PPARGC1A
[Isoform B4-8a]: Cytoplasm 1 PPARGC1A
[Isoform B5]: Nucleus 1 PPARGC1A
[Isoform 9]: Nucleus 1 PPARGC1A


文献列表

  • Maria Rapala-Kozik, Natalia Wolak, Marta Kujda, Agnieszka K Banas. The upregulation of thiamine (vitamin B1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response. BMC plant biology. 2012 Jan; 12(?):2. doi: 10.1186/1471-2229-12-2. [PMID: 22214485]
  • Benjamin T Bikman, Donghai Zheng, Melissa A Reed, Robert C Hickner, Joseph A Houmard, G Lynis Dohm. Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment. American journal of physiology. Regulatory, integrative and comparative physiology. 2010 Jun; 298(6):R1692-9. doi: 10.1152/ajpregu.00190.2009. [PMID: 20393162]
  • Cadence E Minge, Brenton D Bennett, Robert J Norman, Rebecca L Robker. Peroxisome proliferator-activated receptor-gamma agonist rosiglitazone reverses the adverse effects of diet-induced obesity on oocyte quality. Endocrinology. 2008 May; 149(5):2646-56. doi: 10.1210/en.2007-1570. [PMID: 18276752]
  • Shalaka Samant, Hyunwoo Lee, Mahmood Ghassemi, Juan Chen, James L Cook, Alexander S Mankin, Alexander A Neyfakh. Nucleotide biosynthesis is critical for growth of bacteria in human blood. PLoS pathogens. 2008 Feb; 4(2):e37. doi: 10.1371/journal.ppat.0040037. [PMID: 18282099]
  • Ji-Ming Ye, Nick Dzamko, Andrew J Hoy, Miguel A Iglesias, Bruce Kemp, Edward Kraegen. Rosiglitazone treatment enhances acute AMP-activated protein kinase-mediated muscle and adipose tissue glucose uptake in high-fat-fed rats. Diabetes. 2006 Oct; 55(10):2797-804. doi: 10.2337/db05-1315. [PMID: 17003345]
  • Dongying Wu, Sean C Daugherty, Susan E Van Aken, Grace H Pai, Kisha L Watkins, Hoda Khouri, Luke J Tallon, Jennifer M Zaborsky, Helen E Dunbar, Phat L Tran, Nancy A Moran, Jonathan A Eisen. Metabolic complementarity and genomics of the dual bacterial symbiosis of sharpshooters. PLoS biology. 2006 Jun; 4(6):e188. doi: 10.1371/journal.pbio.0040188. [PMID: 16729848]
  • X Yu, S McCorkle, M Wang, Y Lee, J Li, A K Saha, R H Unger, N B Ruderman. Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. Diabetologia. 2004 Nov; 47(11):2012-21. doi: 10.1007/s00125-004-1570-9. [PMID: 15578153]
  • N B Ruderman, H Park, V K Kaushik, D Dean, S Constant, M Prentki, A K Saha. AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise. Acta physiologica Scandinavica. 2003 Aug; 178(4):435-42. doi: 10.1046/j.1365-201x.2003.01164.x. [PMID: 12864749]
  • . . . . doi: . [PMID: 17064924]