chlorоphentermine (BioDeep_00001867967)
Main id: BioDeep_00000006538
代谢物信息卡片
chlorоphentermine
化学式: C10H14ClN (183.0815)
中文名称: 对氯苯丁胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(CC1=CC=C(C=C1)Cl)N
InChI: InChI=1S/C10H14ClN/c1-10(2,12)7-8-3-5-9(11)6-4-8/h3-6H,7,12H2,1-2H3
描述信息
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:3646
- KEGG: C07559
- PubChem: 10007
- DrugBank: DB01556
- ChEMBL: CHEMBL1201269
- MeSH: Chlorphentermine
- CAS: 461-78-9
- PubChem: 9762
- NIKKAJI: J5.768A
- KNApSAcK: 3646
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Richard B Rothman, Jean L Cadet, Christina M Dersch, Michael T McCoy, Elin Lehrmann, Kevin G Becker, Michael Bader, Natalia Alenina, Michael H Baumann. Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension.
PloS one.
2011 Mar; 6(3):e17735. doi:
10.1371/journal.pone.0017735. [PMID: 21464983] - Robert A Ettlin, Junji Kuroda, Stephanie Plassmann, Makoto Hayashi, David E Prentice. Successful drug development despite adverse preclinical findings part 2: examples.
Journal of toxicologic pathology.
2010 Dec; 23(4):213-34. doi:
10.1293/tox.23.213. [PMID: 22272032] - Daniel Crona, Julie Harral, Serge Adnot, Saadia Eddahibi, James West. Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene.
BMC pulmonary medicine.
2009 May; 9(?):19. doi:
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Rapid communications in mass spectrometry : RCM.
2006; 20(5):877-82. doi:
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Respiratory research.
2002; 3(?):9. doi:
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Circulation.
1999 Aug; 100(8):869-75. doi:
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Klinische Monatsblatter fur Augenheilkunde.
1999 Mar; 214(3):178-82. doi:
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Experimental and molecular pathology.
1993 Apr; 58(2):96-104. doi:
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The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
1989 Feb; 37(2):139-47. doi:
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Experimental lung research.
1988; 14(5):619-36. doi:
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Toxicology and applied pharmacology.
1987 Dec; 91(3):469-76. doi:
10.1016/0041-008x(87)90068-8. [PMID: 3424375] - J Burmester, R Hanpft, K Kröplin, R Lüllmann-Rauch, M Patten. Amantadine-induced lipidosis. A cytological and physicochemical study.
Toxicology.
1987 Apr; 44(1):45-59. doi:
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Experimental and molecular pathology.
1987 Feb; 46(1):136-43. doi:
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The Journal of pharmacology and experimental therapeutics.
1986 Jan; 236(1):55-9. doi:
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Journal of lipid research.
1985 Jun; 26(6):735-44. doi:
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Federation proceedings.
1985 Apr; 44(7):2323-7. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
1985 Mar; 13(2):192-6. doi:
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The Journal of pharmacology and experimental therapeutics.
1985 Jan; 232(1):239-43. doi:
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Cell and tissue research.
1985; 239(3):575-87. doi:
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Federation proceedings.
1984 Aug; 43(11):2578-81. doi:
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Acta oto-laryngologica.
1983 Nov; 96(5-6):421-8. doi:
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Experimental and molecular pathology.
1983 Jun; 38(3):368-79. doi:
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Acta oto-laryngologica.
1983 Mar; 95(3-4):307-13. doi:
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Virchows Archiv. B, Cell pathology including molecular pathology.
1983; 43(3):309-16. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
1982 Jan; 10(1):68-73. doi:
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Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie.
1982; 126(1-2):185-95. doi:
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Virchows Archiv. B, Cell pathology including molecular pathology.
1982; 39(1):59-73. doi:
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Life sciences.
1981 Apr; 28(17):1931-8. doi:
10.1016/0024-3205(81)90301-5. [PMID: 7253800] - S C Woodward. Induction and reversal of pulmonary lipid histiocytosis in rats following oral administration of anorectics cloforex and chlorphentermine.
Journal of toxicology and environmental health.
1981 Mar; 7(3-4):569-83. doi:
10.1080/15287398109530002. [PMID: 7197305] - M J Reasor. Drug-induced lipidosis and the alveolar macrophage.
Toxicology.
1981; 20(1):1-33. doi:
10.1016/0300-483x(81)90102-5. [PMID: 7022749] - S Kacew, R Narbaitz. The effect of phenobarbital on chlorphentermine-induced lipidosis-like alterations in renal tissue of adult and newborn rats.
Virchows Archiv. B, Cell pathology including molecular pathology.
1981; 36(1):59-63. doi:
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Arzneimittel-Forschung.
1981; 31(5):795-9. doi:
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Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology.
1981; 215(4):297-303. doi:
10.1007/bf00407668. [PMID: 7013556] - M J Reasor, R A Koshut. Augmentation in antioxidant defense mechanisms in rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
Toxicology and applied pharmacology.
1980 Sep; 55(2):334-41. doi:
10.1016/0041-008x(80)90095-2. [PMID: 7423522] - M J Reasor, R A Koshut, M J McNulty, M A Trush. Chemiluminescence from rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
Toxicology and applied pharmacology.
1980 Mar; 52(3):497-506. doi:
10.1016/0041-008x(80)90344-0. [PMID: 7368220] - H Schmalbruch. The early changes in experimental myopathy induced by chloroquine and chlorphentermine.
Journal of neuropathology and experimental neurology.
1980 Jan; 39(1):65-81. doi:
10.1097/00005072-198001000-00006. [PMID: 7359173] - S Kacew, G A Calderwood. Newborn liver and kidney metabolism as influenced by oxygen toxicity and anorectic drugs.
Journal of toxicology and environmental health.
1980 Jan; 6(1):141-54. doi:
10.1080/15287398009529837. [PMID: 6155472] - M J Reasor. Cumene hydroperoxide-mediated lipid peroxidation in rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
Toxicology.
1980; 18(2):159-68. doi:
10.1016/0300-483x(80)90078-5. [PMID: 7256780] - W Frisch, R Lüllmann-Rauch. Differential effects of chloroquine and of several other amphiphilic cationic drugs upon rat choroid plexus.
Acta neuropathologica.
1979 May; 46(3):203-8. doi:
10.1007/bf00690845. [PMID: 223364] - H Lüllmann, E U Mösinger. Increased lysosomal enzyme activities in tissues of rats suffering from chlorphentermine induced lipidosis.
Biochemical pharmacology.
1979 Apr; 28(7):1015-6. doi:
10.1016/0006-2952(79)90296-x. [PMID: 109091] - R Gräbner, W Meerbach. Morphological and biochemical alterations of the lung after application of chlorphentermine.
Experimentelle Pathologie.
1979; 17(6):303-11. doi:
10.1016/s0014-4908(79)80045-9. [PMID: 527695] - H Schmalbruch. Early changes in chlorphentermine myopathy of rat studied by freeze fracturing.
Muscle & nerve.
1978 Sep; 1(5):421-2. doi:
10.1002/mus.880010516. [PMID: 263983] - D Drenckhahn. Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine.
Virchows Archiv. B, Cell pathology.
1978 May; 27(3):255-66. doi:
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Toxicology.
1978 May; 10(1):77-90. doi:
10.1016/0300-483x(78)90057-4. [PMID: 566970] - S Kacew, R Narbaitz, A J Stevenson. The effects of chlorphentermine and phentermine on certain metabolic parameters associated with development of rat kidney and liver.
Chemico-biological interactions.
1977 Oct; 19(1):61-76. doi:
10.1016/0009-2797(77)90042-4. [PMID: 200375] - D Drenckhahn, R Lüllmann-Rauch. Lens opacities associated with lipidosis-like ultrastructural alterations in rats treated with chloroquine, chlorphentermine, or iprindole.
Experimental eye research.
1977 Jun; 24(6):621-32. doi:
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British journal of clinical pharmacology.
1977 Apr; 4(2):193-200. doi:
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Horumon to rinsho. Clinical endocrinology.
1977 Apr; 25(4):411-4. doi:
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Klinische Monatsblatter fur Augenheilkunde.
1977 Jan; 170(1):64-73. doi:
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Biochemical Society transactions.
1977; 5(4):1005-6. doi:
10.1042/bst0051005. [PMID: 913762] - L Balabanski, T Tashev, A Meretev, Kh Babulkov. [Desopimon in the treatment of obesity].
Vutreshni bolesti.
1976 Dec; 15(6):42-5. doi:
. [PMID: 1014625] - J Gloster, D Heath, P Hasleton, P Harris. Effect of chlorphentermine on the lipids of rat lungs.
Thorax.
1976 Oct; 31(5):558-64. doi:
10.1136/thx.31.5.558. [PMID: 996817] - D Drenckhahn, L Kleine, R Lüllmann-Rauch. Lysosomal alterations in cultured macrophages exposed to anorexigenic and psychotropic drugs.
Laboratory investigation; a journal of technical methods and pathology.
1976 Aug; 35(2):116-23. doi:
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Verhandlungen der Deutschen Gesellschaft fur Innere Medizin.
1976; 82 Pt 2(?):1890-3. doi:
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Biochemical pharmacology.
1975 Dec; 24(24):2225-32. doi:
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Naunyn-Schmiedeberg's archives of pharmacology.
1975; 287 Suppl(?):R54. doi:
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Naunyn-Schmiedeberg's archives of pharmacology.
1975; 288(2-3):261-8. doi:
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Virchows Archiv. B, Cell pathology.
1975; 18(1):51-60. doi:
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Clinical chemistry.
1974 Feb; 20(2):302-4. doi:
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Naunyn-Schmiedeberg's archives of pharmacology.
1974; 282(2):113-22. doi:
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1974; 283(3):331-4. doi:
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1974; 15(4):295-308. doi:
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The Journal of pharmacy and pharmacology.
1973 Mar; 25(3):239-43. doi:
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The Journal of pharmacy and pharmacology.
1971 Nov; 23(11):837-41. doi:
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The Journal of pharmacy and pharmacology.
1971 Apr; 23(4):288-94. doi:
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Arzneimittel-Forschung.
1971 Jan; 21(1):86-93. doi:
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Acta pharmacologica et toxicologica.
1970; 28(5):391-405. doi:
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1967 Dec; 19(?):Suppl:31S-41S. doi:
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Arzneimittel-Forschung.
1967 May; 17(5):625-7. doi:
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Arzneimittel-Forschung.
1966 Oct; 16(10):1311-3. doi:
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Archives internationales de pharmacodynamie et de therapie.
1966 Jun; 161(2):410-22. doi:
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Endokrinologie.
1966 Jun; 50(1):36-41. doi:
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Bollettino della Societa italiana di biologia sperimentale.
1965 Dec; 41(24):1477-8. doi:
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1965 Sep; 17(9):596-7. doi:
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British medical journal.
1965 Aug; 2(5459):453-5. doi:
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