Crotonaldehyde (BioDeep_00001867872)
Main id: BioDeep_00000004212
代谢物信息卡片
Crotonaldehyde
化学式: C4H6O (70.0418626)
中文名称: 2-丁烯醛, 巴豆醛
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC=CC=O
InChI: InChI=1S/C4H6O/c1-2-3-4-5/h2-4H,1H3/b3-2+
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:41607
- KEGG: C19377
- PubChem: 447466
- DrugBank: DB04381
- ChEMBL: CHEMBL1086445
- CAS: 4170-30-3
- CAS: 123-73-9
- PubChem: 124490049
- PDB-CCD: CRD
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 205369 - Artemisia judaica: 10.1016/0305-1978(85)90037-7
- 4097 - Nicotiana tabacum: 10.1016/0378-8741(88)90069-4
- 354530 - Zanthoxylum schinifolium: 10.1021/JF0728101
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Eva Tejedor-Calvo, Sergi Garcia-Barreda, José Sebastián Dambolena, David Pelissero, Sergio Sánchez, Pedro Marco, Eduardo Nouhra. Aromatic profile of black truffle grown in Argentina: Characterization of commercial categories and alterations associated to maturation, harvesting date and orchard management practices.
Food research international (Ottawa, Ont.).
2023 11; 173(Pt 1):113300. doi:
10.1016/j.foodres.2023.113300. [PMID: 37803611] - Guang Cheng, Jiehong Guo, Renwei Wang, Jian-Min Yuan, Silvia Balbo, Stephen S Hecht. Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study.
Chemical research in toxicology.
2023 Feb; 36(2):305-312. doi:
10.1021/acs.chemrestox.2c00393. [PMID: 36719849] - Jordan Lynch, Lexiao Jin, Andre Richardson, Ganapathy Jagatheesan, Pawel Lorkiewicz, Zhengzhi Xie, Whitney S Theis, Gregg Shirk, Marina V Malovichko, Aruni Bhatnagar, Sanjay Srivastava, Daniel J Conklin. Acute and chronic vascular effects of inhaled crotonaldehyde in mice: Role of TRPA1.
Toxicology and applied pharmacology.
2020 09; 402(?):115120. doi:
10.1016/j.taap.2020.115120. [PMID: 32634517] - Menglan Chen, Steven G Carmella, Yupeng Li, Yingchun Zhao, Stephen S Hecht. Resolution and Quantitation of Mercapturic Acids Derived from Crotonaldehyde, Methacrolein, and Methyl Vinyl Ketone in the Urine of Smokers and Nonsmokers.
Chemical research in toxicology.
2020 02; 33(2):669-677. doi:
10.1021/acs.chemrestox.9b00491. [PMID: 31957442] - Rosario Zamora, Cristina M Lavado-Tena, Francisco J Hidalgo. Oligomerization of reactive carbonyls in the presence of ammonia-producing compounds: A route for the production of pyridines in foods.
Food chemistry.
2020 Jan; 304(?):125284. doi:
10.1016/j.foodchem.2019.125284. [PMID: 31476546] - Biao Zhang, Ping Wei, Jinlong Men, Shuman Zhang, Hua Shao, Zhihu Zhang. Crotonaldehyde-induced alterations in testicular enzyme function and hormone levels, and apoptosis in the testes of male Wistar rats are associated with oxidative damage.
Toxicology mechanisms and methods.
2020 Jan; 30(1):19-32. doi:
10.1080/15376516.2019.1646369. [PMID: 31345100] - Hasmik Grigoryan, Courtney Schiffman, Marc J Gunter, Alessio Naccarati, Silvia Polidoro, Sonia Dagnino, Sandrine Dudoit, Paolo Vineis, Stephen M Rappaport. Cys34 Adductomics Links Colorectal Cancer with the Gut Microbiota and Redox Biology.
Cancer research.
2019 12; 79(23):6024-6031. doi:
10.1158/0008-5472.can-19-1529. [PMID: 31641032] - S S Li, B Zhang, S M Zhang, Z H Zhang, Y N Wei. [Study on lung injury induced by subchronic exposure to crotonaldehyde in male rats].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2019 Oct; 37(10):728-731. doi:
10.3760/cma.j.issn.1001-9391.2019.10.003. [PMID: 31726501] - Yanbin Su, Chengyu Sun, Yan Chen, Shichang Liu, Ning Jing, Shuxin Li. Toxic trans-crotonaldehyde in mitochondria intercepted by oxyresveratrol contributing to anticancer.
IUBMB life.
2019 07; 71(7):1014-1020. doi:
10.1002/iub.2051. [PMID: 31012998] - Biao Zhang, Shuangshuang Li, Jinlong Men, Cheng Peng, Hua Shao, Zhihu Zhang. Long-term exposure to crotonaldehyde causes heart and kidney dysfunction through induction of inflammatory and oxidative damage in male Wistar rats.
Toxicology mechanisms and methods.
2019 May; 29(4):263-275. doi:
10.1080/15376516.2018.1542474. [PMID: 30426860] - S S Li, B Zhang, Z H Zhang. [Study on oxidative stress damage of reproductive organs in male rats induced by long-term exposure to crotonaldehyde].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2019 Apr; 37(4):241-246. doi:
10.3760/cma.j.issn.1001-9391.2019.04.001. [PMID: 31177687] - Asja A Kroeger, Amir Karton. A computational foray into the mechanism and catalysis of the adduct formation reaction of guanine with crotonaldehyde.
Journal of computational chemistry.
2019 02; 40(4):630-637. doi:
10.1002/jcc.25595. [PMID: 30368841] - B Zhang, S S Li, J L Men, Z H Zhang. [Effect of long-term crotonaldehyde exposure on heart damage in male rats].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2018 Sep; 36(9):647-652. doi:
10.3760/cma.j.issn.1001-9391.2018.09.002. [PMID: 30419665] - B Zhang, S S Li, L Li, R Han, Z H Zhang. [Effect of crotonaldehyde long-term exposure induced kidney inflammatory and oxidative injury in male rats].
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2018 Aug; 36(8):580-584. doi:
10.3760/cma.j.issn.1001-9391.2018.08.004. [PMID: 30317805] - Pritha Bagchi, Nathan Geldner, B Rey deCastro, Víctor R De Jesús, Sang Ki Park, Benjamin C Blount. Crotonaldehyde exposure in U.S. tobacco smokers and nonsmokers: NHANES 2005-2006 and 2011-2012.
Environmental research.
2018 05; 163(?):1-9. doi:
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Scientific reports.
2017 08; 7(1):10081. doi:
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PloS one.
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2014 Mar; 953-954(?):147-52. doi:
10.1016/j.jchromb.2014.02.009. [PMID: 24614624] - Michael Granvogl. Development of three stable isotope dilution assays for the quantitation of (E)-2-butenal (crotonaldehyde) in heat-processed edible fats and oils as well as in food.
Journal of agricultural and food chemistry.
2014 Feb; 62(6):1272-82. doi:
10.1021/jf404902m. [PMID: 24428123] - Dong Sun Ryu, Hana Yang, Seung Eun Lee, Cheung-Seog Park, Young-Ho Jin, Yong Seek Park. Crotonaldehyde induces heat shock protein 72 expression that mediates anti-apoptotic effects in human endothelial cells.
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2013 Nov; 223(2):116-23. doi:
10.1016/j.toxlet.2013.09.010. [PMID: 24070736] - Camila C M Garcia, Florêncio P Freitas, Angélica B Sanchez, Paolo Di Mascio, Marisa H G Medeiros. Elevated α-methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine levels in urinary samples from individuals exposed to urban air pollution.
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10.1021/tx400273q. [PMID: 24168144] - Steven G Carmella, Menglan Chen, Adam Zarth, Stephen S Hecht. High throughput liquid chromatography-tandem mass spectrometry assay for mercapturic acids of acrolein and crotonaldehyde in cigarette smokers' urine.
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