parathion (BioDeep_00001867643)
Main id: BioDeep_00000001403
代谢物信息卡片
化学式: C10H14NO5PS (291.03302840000003)
中文名称: 巴拉松
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOP(=S)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-]
InChI: InChI=1S/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
描述信息
D018377 - Neurotransmitter Agents > D018678 - Cholinergic Agents > D002800 - Cholinesterase Inhibitors
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
D010575 - Pesticides > D007306 - Insecticides
D004791 - Enzyme Inhibitors
D016573 - Agrochemicals
同义名列表
1 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:27928
- KEGG: C06604
- PubChem: 991
- ChEMBL: CHEMBL261919
- MeSH: Parathion
- CAS: 56-38-2
- MetaboLights: MTBLC27928
- PubChem: 8830
- PDB-CCD: WYS
- NIKKAJI: J2.318C
- RefMet: Parathion
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Saroj K Amar, Keri B Donohue, Kurt A Gust. Cellular and molecular responses to ethyl-parathion in undifferentiated SH-SY5Y cells provide neurotoxicity pathway indicators for organophosphorus impacts.
Toxicological sciences : an official journal of the Society of Toxicology.
2023 Feb; 191(2):285-295. doi:
10.1093/toxsci/kfac125
. [PMID: 36458919] - Kelin Tao, Haixia Tian, Jing Fan, Dongxiao Li, Chaoyang Liu, Mallavarapu Megharaj, Huayong Li, Min Hu, Hanzhong Jia, Wenxiang He. Kinetics and catalytic efficiency of soil fluorescein diacetate hydrolase under the pesticide parathion stress.
The Science of the total environment.
2021 Jun; 771(?):144835. doi:
10.1016/j.scitotenv.2020.144835
. [PMID: 33548707] - Ali Salari, Kambiz Roshanaei, Bahram Rasoulian, Javad Khalili Fard. Carvacrol loaded beta cyclodextrin-alginate-chitosan based nanoflowers attenuates renal toxicity induced by malathion and parathion: A comparative toxicity.
Pesticide biochemistry and physiology.
2021 Feb; 172(?):104747. doi:
10.1016/j.pestbp.2020.104747
. [PMID: 33518056] - Duo Miao, Song Zhao, Kecheng Zhu, Peng Zhang, Tiecheng Wang, Hanzhong Jia, Hongwen Sun. Activation of persulfate and removal of ethyl-parathion from soil: Effect of microwave irradiation.
Chemosphere.
2020 Aug; 253(?):126679. doi:
10.1016/j.chemosphere.2020.126679
. [PMID: 32283425] - Lindsay M Jaacks, Nancy Diao, Antonia M Calafat, Maria Ospina, Maitreyi Mazumdar, Md Omar Sharif Ibne Hasan, Robert Wright, Quazi Quamruzzaman, David C Christiani. Association of prenatal pesticide exposures with adverse pregnancy outcomes and stunting in rural Bangladesh.
Environment international.
2019 12; 133(Pt B):105243. doi:
10.1016/j.envint.2019.105243
. [PMID: 31675560] - Seyedhossein Hekmatimoghaddam, Maryam Iman, Hossein Shahdadi Sardo, Ali Jebali. Gelatin hydrogel containing cerium oxide nanoparticles covered by interleukin-17 aptamar as an anti- inflammatory agent for brain inflammation.
Journal of neuroimmunology.
2019 01; 326(?):79-83. doi:
10.1016/j.jneuroim.2018.11.011
. [PMID: 30544018] - Mohamed Khairy, Haytham A Ayoub, Craig E Banks. Non-enzymatic electrochemical platform for parathion pesticide sensing based on nanometer-sized nickel oxide modified screen-printed electrodes.
Food chemistry.
2018 Jul; 255(?):104-111. doi:
10.1016/j.foodchem.2018.02.004
. [PMID: 29571455] - Qian Bo, Lu Chen, Yahui Liu, Chunjie Chang, Xiaoli Ying, Fengliang Li, Luogen Cheng. Analysis of Ran related to pesticide resistance in Drosophila Kc cells.
Gene.
2018 Jul; 663(?):131-137. doi:
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Insect biochemistry and molecular biology.
2017 10; 89(?):11-16. doi:
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Biosensors & bioelectronics.
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Fluids and barriers of the CNS.
2016 Jul; 13(1):10. doi:
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. [PMID: 27396356] - Haiyan Shi, Enze Sheng, Lu Feng, Liangliang Zhou, Xiude Hua, Minghua Wang. Simultaneous detection of imidacloprid and parathion by the dual-labeled time-resolved fluoroimmunoassay.
Environmental science and pollution research international.
2015 Oct; 22(19):14882-90. doi:
10.1007/s11356-015-4697-y
. [PMID: 25994268] - Jing Liu, Loren Parsons, Carey Pope. Comparative effects of parathion and chlorpyrifos on endocannabinoid and endocannabinoid-like lipid metabolites in rat striatum.
Neurotoxicology.
2015 Sep; 50(?):20-7. doi:
10.1016/j.neuro.2015.07.006
. [PMID: 26215119] - Wei Wang, Si-Lu Liu, Yang-Yang Liu, Chuan-Ling Qiao, Shao-Liang Chen, Feng Cui. Over-transcription of genes in a parathion-resistant strain of mosquito Culex pipiens quinquefasciatus.
Insect science.
2015 Feb; 22(1):150-6. doi:
10.1111/1744-7917.12106
. [PMID: 24431295] - Wen S Lan, Ti K Lu, Zhi F Qin, Xiu J Shi, Jin J Wang, Yun F Hu, Bin Chen, Yi H Zhu, Zheng Liu. Genetically modified microorganism Spingomonas paucimobilis UT26 for simultaneously degradation of methyl-parathion and γ-hexachlorocyclohexane.
Ecotoxicology (London, England).
2014 Jul; 23(5):840-50. doi:
10.1007/s10646-014-1224-8
. [PMID: 24648032] - Xiangjiang Tang, Bo Liang, Tuyong Yi, Giuseppe Manco, Ilaria Palchetti, Ilariapalchetti, Aihua Liu. Cell surface display of organophosphorus hydrolase for sensitive spectrophotometric detection of p-nitrophenol substituted organophosphates.
Enzyme and microbial technology.
2014 Feb; 55(?):107-12. doi:
10.1016/j.enzmictec.2013.10.006
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Food chemistry.
2013 Nov; 141(2):1398-405. doi:
10.1016/j.foodchem.2013.04.008
. [PMID: 23790930] - R Nishino, T Fukuyama, Y Tajima, L Miyashita, Y Watanabe, H Ueda, T Kosaka. Prior oral exposure to environmental immunosuppressive chemicals methoxychlor, parathion, or piperonyl butoxide aggravates allergic airway inflammation in NC/Nga mice.
Toxicology.
2013 Jul; 309(?):1-8. doi:
10.1016/j.tox.2013.03.018
. [PMID: 23583882] - Riccardo Funari, Bartolomeo Della Ventura, Luigi Schiavo, Rosario Esposito, Carlo Altucci, Raffaele Velotta. Detection of parathion pesticide by quartz crystal microbalance functionalized with UV-activated antibodies.
Analytical chemistry.
2013 Jul; 85(13):6392-7. doi:
10.1021/ac400852c
. [PMID: 23721081] - Falicia L Edwards, Clement G Yedjou, Paul B Tchounwou. Involvement of oxidative stress in methyl parathion and parathion-induced toxicity and genotoxicity to human liver carcinoma (HepG₂) cells.
Environmental toxicology.
2013 Jun; 28(6):342-8. doi:
10.1002/tox.20725
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Toxicology letters.
2012 Sep; 213(3):392-401. doi:
10.1016/j.toxlet.2012.07.018
. [PMID: 22842586] - Jean-Louis Mariage, Anja Gallinat, Philippe Hantson. Organ donation following fatal organophosphate poisoning.
Transplant international : official journal of the European Society for Organ Transplantation.
2012 Jun; 25(6):e71-2. doi:
10.1111/j.1432-2277.2012.01466.x
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Nutritional neuroscience.
2012 Mar; 15(2):62-9. doi:
10.1179/1476830511y.0000000034
. [PMID: 22333997] - Ellen G Duysen, John R Cashman, Lawrence M Schopfer, Florian Nachon, Patrick Masson, Oksana Lockridge. Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran.
Chemico-biological interactions.
2012 Feb; 195(3):189-98. doi:
10.1016/j.cbi.2011.12.006
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The protein journal.
2012 Feb; 31(2):120-8. doi:
10.1007/s10930-011-9380-7
. [PMID: 22173274] - Reza Ahmadkhaniha, Nasrin Samadi, Mona Salimi, Parisa Sarkhail, Noushin Rastkari. Simultaneous determination of parathion, malathion, diazinon, and pirimiphos methyl in dried medicinal plants using solid-phase microextraction fibre coated with single-walled carbon nanotubes.
TheScientificWorldJournal.
2012; 2012(?):627607. doi:
10.1100/2012/627607
. [PMID: 22645439] - T Fukuyama, Y Tajima, K Hayashi, H Ueda, T Kosaka. Prior or coinstantaneous oral exposure to environmental immunosuppressive agents aggravates mite allergen-induced atopic dermatitis-like immunoreaction in NC/Nga mice.
Toxicology.
2011 Nov; 289(2-3):132-40. doi:
10.1016/j.tox.2011.08.003
. [PMID: 21864637] - Ellen G Duysen, Oksana Lockridge. Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons.
Toxicology and applied pharmacology.
2011 Sep; 255(2):214-20. doi:
10.1016/j.taap.2011.06.021
. [PMID: 21767560] - Robert J Foxenberg, Corie A Ellison, James B Knaak, Changxing Ma, James R Olson. Cytochrome P450-specific human PBPK/PD models for the organophosphorus pesticides: chlorpyrifos and parathion.
Toxicology.
2011 Jul; 285(1-2):57-66. doi:
10.1016/j.tox.2011.04.002
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Toxicology.
2011 Feb; 280(3):77-87. doi:
10.1016/j.tox.2010.11.008
. [PMID: 21115097] - T Leon Lassiter, Ian T Ryde, Edward D Levin, Frederic J Seidler, Theodore A Slotkin. Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits.
Brain research bulletin.
2010 Jan; 81(1):85-91. doi:
10.1016/j.brainresbull.2009.07.002
. [PMID: 19615431] - Theodore A Slotkin, Nicola Wrench, Ian T Ryde, T Leon Lassiter, Edward D Levin, Frederic J Seidler. Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood.
Neurotoxicology and teratology.
2009 Nov; 31(6):390-9. doi:
10.1016/j.ntt.2009.07.003
. [PMID: 19616088] - Horst Thiermann, Franz Worek, Peter Eyer, Florian Eyer, Norbert Felgenhauer, Thomas Zilker. Obidoxime in acute organophosphate poisoning: 2 - PK/PD relationships.
Clinical toxicology (Philadelphia, Pa.).
2009 Sep; 47(8):807-13. doi:
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Clinical toxicology (Philadelphia, Pa.).
2009 Sep; 47(8):798-806. doi:
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. [PMID: 19778163] - Theodore A Slotkin, Edward D Levin, Frederic J Seidler. Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood.
Neurotoxicology and teratology.
2009 Jan; 31(1):11-7. doi:
10.1016/j.ntt.2008.08.004
. [PMID: 18773955] - T Leon Lassiter, Ian T Ryde, Emiko A Mackillop, Kathleen K Brown, Edward D Levin, Frederic J Seidler, Theodore A Slotkin. Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood.
Environmental health perspectives.
2008 Nov; 116(11):1456-62. doi:
10.1289/ehp.11673
. [PMID: 19057696] - D Jun, L Musilova, K Kuca, J Kassa, J Bajgar. Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro.
Chemico-biological interactions.
2008 Sep; 175(1-3):421-4. doi:
10.1016/j.cbi.2008.05.004
. [PMID: 18617161] - M B Sabbe, D Desruelles, W Lissens. Is beta-glucuronidase a clinical useful biomarker for an acute organophosphorus poisoning?.
Human & experimental toxicology.
2008 May; 27(5):431-3. doi:
10.1177/0960327108094614
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Toxicology and applied pharmacology.
2008 Apr; 228(1):42-8. doi:
10.1016/j.taap.2007.11.021
. [PMID: 18164358] - J Boucher, F Cengelli, D Trumbic, I W Marison. Sorption of hydrophobic organic compounds (HOC) in rapeseed oil bodies.
Chemosphere.
2008 Feb; 70(8):1452-8. doi:
10.1016/j.chemosphere.2007.08.065
. [PMID: 17942138] - Li-Chun Xu, Lu Liu, Xiang-Mei Ren, Mei-Rong Zhang, Ning Cong, Ai-Qin Xu, Ji-Hong Shao. Evaluation of androgen receptor transcriptional activities of some pesticides in vitro.
Toxicology.
2008 Jan; 243(1-2):59-65. doi:
10.1016/j.tox.2007.09.028
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Water research.
2007 Aug; 41(15):3209-16. doi:
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Langmuir : the ACS journal of surfaces and colloids.
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Biosensors & bioelectronics.
2007 Jun; 22(12):3001-7. doi:
10.1016/j.bios.2006.12.029
. [PMID: 17270415] - Richard P Moody, Mohammed Akram, Eva Dickson, Ih Chu. In vitro dermal absorption of methyl salicylate, ethyl parathion, and malathion: first responder safety.
Journal of toxicology and environmental health. Part A.
2007 Jun; 70(12):985-99. doi:
10.1080/15287390600870874
. [PMID: 17497409] - Minze Leistra, Frederik van den Berg. Volatilization of parathion and chlorothalonil from a potato crop simulated by the PEARL model.
Environmental science & technology.
2007 Apr; 41(7):2243-8. doi:
10.1021/es0627242
. [PMID: 17438770] - Jing Liu, Ramesh C Gupta, John T Goad, Subramanya Karanth, Carey Pope. Modulation of parathion toxicity by glucose feeding: Is nitric oxide involved?.
Toxicology and applied pharmacology.
2007 Mar; 219(2-3):106-13. doi:
10.1016/j.taap.2006.11.005
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Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al.
2006 Dec; 30(3):423-9. doi:
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. [PMID: 17375462] - E Gallardo, M Barroso, C Margalho, A Cruz, D N Vieira, M López-Rivadulla. Determination of parathion in biological fluids by means of direct solid-phase microextraction.
Analytical and bioanalytical chemistry.
2006 Nov; 386(6):1717-26. doi:
10.1007/s00216-006-0735-4
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Applied microbiology and biotechnology.
2006 Aug; 72(1):103-108. doi:
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Intensive care medicine.
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. [PMID: 16479380] - Masao Fukushima, Toshiyuki Katagi. Photodegradation of fenitrothion and parathion in tomato epicuticular waxes.
Journal of agricultural and food chemistry.
2006 Jan; 54(2):474-9. doi:
10.1021/jf052113d
. [PMID: 16417307] - R Kacham, S Karanth, P Baireddy, J Liu, C Pope. Interactive toxicity of chlorpyrifos and parathion in neonatal rats: role of esterases in exposure sequence-dependent toxicity.
Toxicology and applied pharmacology.
2006 Jan; 210(1-2):142-9. doi:
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Hybridoma (2005).
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Toxicology.
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Journal of economic entomology.
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Toxicology letters.
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Chemical research in toxicology.
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Journal of occupational and environmental medicine.
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Toxicological reviews.
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Environmental health perspectives.
2002 Dec; 110 Suppl 6(?):1031-6. doi:
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Environmental health perspectives.
2002 May; 110(5):549-53. doi:
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Journal of toxicology. Clinical toxicology.
2002; 40(5):563-5. doi:
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Rapid communications in mass spectrometry : RCM.
2002; 16(7):639-45. doi:
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. [PMID: 11921240] - S Karanth, K Olivier, J Liu, C Pope. In vivo interaction between chlorpyrifos and parathion in adult rats: sequence of administration can markedly influence toxic outcome.
Toxicology and applied pharmacology.
2001 Dec; 177(3):247-55. doi:
10.1006/taap.2001.9312
. [PMID: 11749124] - K Olivier, J Liu, S Karanth, H Zhang, D S Roane, C N Pope. Glucose feeding exacerbates parathion-induced neurotoxicity.
Journal of toxicology and environmental health. Part A.
2001 Jun; 63(4):253-71. doi:
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. [PMID: 11437059] - S Ribeiro, J P Sousa, A J Nogueira, A M Soares. Effect of endosulfan and parathion on energy reserves and physiological parameters of the terrestrial isopod Porcellio dilatatus.
Ecotoxicology and environmental safety.
2001 Jun; 49(2):131-8. doi:
10.1006/eesa.2001.2045
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