dihomo-gamma-linolenic acid (BioDeep_00000405544)

Main id: BioDeep_00000628737

 

BioNovoGene_Lab2019 natural product


代谢物信息卡片


cis-8,11,14-Eicosatrienoic Acid

化学式: C20H34O2 (306.2559)
中文名称: 顺式-8,11,14-二十碳三烯酸, 8,11-14-廿碳三烯酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
InChI: InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-

描述信息

COVID info from WikiPathways
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

4 个代谢物同义名

cis-8,11,14-Eicosatrienoic Acid; dihomo-gamma-linolenic acid; Dihomo-gamma-linolenate; Dihomo-gamma-linolenic acid



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

165 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALB, ALOX5, APOE, FASN, GLA, PLA2G12A, PTGS1, PTGS2
Peripheral membrane protein 4 ALOX5, AP1S2, PTGS1, PTGS2
Endoplasmic reticulum membrane 6 FADS1, FADS2, GLA, PTGS1, PTGS2, SCD
Nucleus 2 ALB, APOE
cytosol 5 ALB, ALOX5, AP1S2, FASN, PRKCQ
dendrite 1 APOE
centrosome 1 ALB
nucleoplasm 1 ALOX5
Cell membrane 1 TNF
Cytoplasmic side 1 AP1S2
Multi-pass membrane protein 3 FADS1, FADS2, SCD
cell surface 1 TNF
glutamatergic synapse 1 APOE
Golgi apparatus 6 ALB, AP1S2, APOE, FASN, GLA, PTGS1
Golgi membrane 2 AP1S2, INS
lysosomal membrane 1 AP1S2
neuronal cell body 2 APOE, TNF
Cytoplasm, cytosol 1 ALOX5
Lysosome 1 GLA
plasma membrane 7 APOE, F2, FADS2, FASN, IGHE, PRKCQ, TNF
Membrane 6 APOE, FADS1, FADS2, FASN, GLA, SCD
caveola 1 PTGS2
extracellular exosome 6 ALB, APOE, F2, FASN, GLA, PTGS1
endoplasmic reticulum 4 ALB, APOE, PTGS2, SCD
extracellular space 10 ALB, ALOX5, APOE, CRP, F2, IGHE, IL10, IL6, INS, TNF
lysosomal lumen 1 GLA
perinuclear region of cytoplasm 1 ALOX5
mitochondrion 1 FADS1
protein-containing complex 2 ALB, PTGS2
intracellular membrane-bounded organelle 3 AP1S2, FADS1, PTGS1
Microsome membrane 2 PTGS1, PTGS2
Single-pass type I membrane protein 1 IGHE
Secreted 8 ALB, APOE, CRP, F2, IL10, IL6, INS, PLA2G12A
extracellular region 12 ALB, ALOX5, APOE, CRP, F2, GLA, IGHE, IL10, IL6, INS, PLA2G12A, TNF
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
photoreceptor outer segment 1 PTGS1
Nucleus membrane 1 ALOX5
nuclear membrane 1 ALOX5
external side of plasma membrane 1 TNF
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
nucleolus 1 SCD
Early endosome 2 AP1S2, APOE
Membrane, clathrin-coated pit 1 AP1S2
clathrin-coated pit 1 AP1S2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Cytoplasm, perinuclear region 1 ALOX5
Membrane raft 1 TNF
extracellular matrix 1 APOE
collagen-containing extracellular matrix 2 APOE, F2
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 2 PTGS1, PTGS2
ciliary basal body 1 ALB
IgE immunoglobulin complex 1 IGHE
phagocytic cup 1 TNF
centriole 1 ALB
Secreted, extracellular space 1 APOE
spindle pole 1 ALB
blood microparticle 3 ALB, APOE, F2
[Isoform 2]: Cell membrane 1 IGHE
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
Endomembrane system 2 AP1S2, PTGS1
endosome lumen 1 INS
[Isoform 1]: Endoplasmic reticulum membrane 1 FADS1
Cytoplasmic vesicle membrane 1 AP1S2
Melanosome 2 APOE, FASN
trans-Golgi network membrane 1 AP1S2
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 2 ALOX5, INS
Golgi lumen 2 F2, INS
endoplasmic reticulum lumen 6 ALB, APOE, F2, IL6, INS, PTGS2
nuclear matrix 1 ALOX5
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
azurophil granule lumen 1 GLA
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GLA, INS
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
clathrin-coated endocytic vesicle membrane 1 APOE
endoplasmic reticulum-Golgi intermediate compartment 1 GLA
synaptic cleft 1 APOE
AP-type membrane coat adaptor complex 1 AP1S2
membrane coat 1 AP1S2
AP-1 adaptor complex 1 AP1S2
[Isoform 2]: Endoplasmic reticulum membrane 1 FADS1
[Isoform 3]: Cell membrane 1 IGHE
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 1 APOE
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
interleukin-6 receptor complex 1 IL6
Nucleus intermembrane space 1 ALOX5
glycogen granule 1 FASN
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Hiroshi Kawashima, Katsuhiko Yoshizawa. The physiological and pathological properties of Mead acid, an endogenous multifunctional n-9 polyunsaturated fatty acid. Lipids in health and disease. 2023 Oct; 22(1):172. doi: 10.1186/s12944-023-01937-6. [PMID: 37838679]
  • Nicolas G Bazan, Jeff X Ji, Samuel E Baum. Awakening neural survival mechanisms after stroke: Lipid metabolism in brain-autonomous repair. Neuron. 2023 Oct; 111(19):2945-2948. doi: 10.1016/j.neuron.2023.08.020. [PMID: 37797578]
  • Joanna Bajerska, Aleksandra Skoczek-Rubińska, Lidia Małczak, Vesna Vucic, Aleksandra Arsic, Milica Kojadinovic, Danijela Ristic-Medic. Plasma fatty acid composition and some markers of dietary habits are associated with cardiovascular disease risk determined by an atherogenic plasma index in postmenopausal women. Nutrition research (New York, N.Y.). 2023 May; 115(?):47-60. doi: 10.1016/j.nutres.2023.05.008. [PMID: 37300953]
  • Liman Luo, Yan Yang, Menglu Fu, Jinlan Luo, Wenhua Li, Ling Tu, Ruolan Dong. 11,12-EET suppressed LPS induced TF expression and thrombus formation by accelerating mRNA degradation rate via strengthening PI3K-Akt signaling pathway and inhibiting p38-TTP pathway. Prostaglandins & other lipid mediators. 2023 Apr; 167(?):106740. doi: 10.1016/j.prostaglandins.2023.106740. [PMID: 37119935]
  • Anne-Mari Mustonen, Petteri Nieminen. Dihomo-γ-Linolenic Acid (20:3n-6)-Metabolism, Derivatives, and Potential Significance in Chronic Inflammation. International journal of molecular sciences. 2023 Jan; 24(3):. doi: 10.3390/ijms24032116. [PMID: 36768438]
  • Marcos A Perez, Andrea J Clostio, Isabel R Houston, Jimena Ruiz, Leslie Magtanong, Scott J Dixon, Jennifer L Watts. Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity. PLoS genetics. 2022 09; 18(9):e1010436. doi: 10.1371/journal.pgen.1010436. [PMID: 36178986]
  • Marzia Savini, Andrew Folick, Yi-Tang Lee, Feng Jin, André Cuevas, Matthew C Tillman, Jonathon D Duffy, Qian Zhao, Isaiah A Neve, Pei-Wen Hu, Yong Yu, Qinghao Zhang, Youqiong Ye, William B Mair, Jin Wang, Leng Han, Eric A Ortlund, Meng C Wang. Lysosome lipid signalling from the periphery to neurons regulates longevity. Nature cell biology. 2022 06; 24(6):906-916. doi: 10.1038/s41556-022-00926-8. [PMID: 35681008]
  • Jie Zhang, Chuang Yang, Hongmei Qiu, Junxia Yang, Ke Wu, Shumei Ding, Chengyan Jiang, Qingsong Jiang. 14,15-EET involved in the development of diabetic cardiac hypertrophy mediated by PPARs. Prostaglandins & other lipid mediators. 2022 04; 159(?):106620. doi: 10.1016/j.prostaglandins.2022.106620. [PMID: 35091081]
  • Jingquan He, Chiyu Ma, Donge Tang, Shaoyun Zhong, Xiaofang Yuan, Fengping Zheng, Zhipeng Zeng, Yumei Chen, Dongzhou Liu, Xiaoping Hong, Weier Dai, Lianghong Yin, Yong Dai. Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus. Frontiers in immunology. 2022; 13(?):964901. doi: 10.3389/fimmu.2022.964901. [PMID: 36275708]
  • Nalin Singh, Anders Vik, Daniel B Lybrand, Christophe Morisseau, Bruce D Hammock. New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation. Chemical research in toxicology. 2021 12; 34(12):2579-2591. doi: 10.1021/acs.chemrestox.1c00347. [PMID: 34817988]
  • Neil K Huang, Mary L Biggs, Nirupa R Matthan, Luc Djoussé, W T Longstreth, Kenneth J Mukamal, David S Siscovick, Alice H Lichtenstein. Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. Journal of the American Heart Association. 2021 11; 10(22):e022725. doi: 10.1161/jaha.121.022725. [PMID: 34755529]
  • Yun Ding, Pengjie Tu, Yiyong Chen, Yangyun Huang, Xiaojie Pan, Wenshu Chen. CYP2J2 and EETs protect against pulmonary arterial hypertension with lung ischemia-reperfusion injury in vivo and in vitro. Respiratory research. 2021 Nov; 22(1):291. doi: 10.1186/s12931-021-01891-w. [PMID: 34774051]
  • Dennis Winston T Nilsen, Peder Langeland Myhre, Are Kalstad, Erik Berg Schmidt, Harald Arnesen, Ingebjørg Seljeflot. Serum Levels of Dihomo-Gamma (γ)-Linolenic Acid (DGLA) Are Inversely Associated with Linoleic Acid and Total Death in Elderly Patients with a Recent Myocardial Infarction. Nutrients. 2021 Sep; 13(10):. doi: 10.3390/nu13103475. [PMID: 34684479]
  • Jacquelyn Cheng, Haim Bar, Elad Tako. Zinc Status Index (ZSI) for Quantification of Zinc Physiological Status. Nutrients. 2021 Sep; 13(10):. doi: 10.3390/nu13103399. [PMID: 34684398]
  • Christian B Bergmann, Bruce D Hammock, Debin Wan, Falk Gogolla, Holly Goetzman, Charles C Caldwell, Dorothy M Supp. TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function. Scientific reports. 2021 08; 11(1):16555. doi: 10.1038/s41598-021-96014-2. [PMID: 34400718]
  • Shuiqing Hu, Jinlan Luo, Menglu Fu, Liman Luo, Yueting Cai, Wenhua Li, Yuanyuan Li, Ruolan Dong, Yan Yang, Ling Tu, Xizhen Xu. Soluble epoxide hydrolase deletion attenuated nicotine-induced arterial stiffness via limiting the loss of SIRT1. American journal of physiology. Heart and circulatory physiology. 2021 08; 321(2):H353-H368. doi: 10.1152/ajpheart.00979.2020. [PMID: 34142887]
  • Shanthi Nagarajan, Zu Yuan Qian, Parthiban Marimuthu, Nabil J Alkayed, Sanjiv Kaul, Anthony P Barnes. Mapping the Molecular Architecture Required for Lipid-Binding Pockets Using a Subset of Established and Orphan G-Protein Coupled Receptors. Journal of chemical information and modeling. 2021 07; 61(7):3442-3452. doi: 10.1021/acs.jcim.1c00335. [PMID: 34242503]
  • Jacqueline Pontes Monteiro, Carlos A Fuzo, Fábio V Ued, Jim Kaput. Dietary patterns related to zinc and polyunsaturated fatty acids intake are associated with serum linoleic/dihomo-γ-linolenic ratio in NHANES males and females. Scientific reports. 2021 06; 11(1):12215. doi: 10.1038/s41598-021-91611-7. [PMID: 34108562]
  • Rozenn N Lemaitre, Paul N Jensen, Maxwell Zeigler, Julie Denham, Amanda M Fretts, Jason G Umans, Barbara V Howard, Colleen M Sitlani, Barbara McKnight, Sina A Gharib, Irena B King, David S Siscovick, Bruce M Psaty, Nona Sotoodehnia, Rheem A Totah. Plasma epoxyeicosatrienoic acids and dihydroxyeicosatrieonic acids, insulin, glucose and risk of diabetes: The strong heart study. EBioMedicine. 2021 Apr; 66(?):103279. doi: 10.1016/j.ebiom.2021.103279. [PMID: 33752126]
  • John D Imig, Md Abdul Hye Khan, Anna Burkhan, Guan Chen, Adeniyi Michael Adebesin, John R Falck. Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity. International journal of molecular sciences. 2021 Mar; 22(6):. doi: 10.3390/ijms22062793. [PMID: 33801911]
  • Yosuke Tsuchiya, Hisashi Ueda, Kenichi Yanagimoto, Ayaka Kato, Eisuke Ochi. 4-week eicosapentaenoic acid-rich fish oil supplementation partially protects muscular damage following eccentric contractions. Journal of the International Society of Sports Nutrition. 2021 Mar; 18(1):18. doi: 10.1186/s12970-021-00411-x. [PMID: 33648546]
  • Menglu Fu, Jing Yu, Zhihui Chen, Ying Tang, Ruolan Dong, Yan Yang, Jinlan Luo, Shuiqing Hu, Ling Tu, Xizhen Xu. Epoxyeicosatrienoic acids improve glucose homeostasis by preventing NF-κB-mediated transcription of SGLT2 in renal tubular epithelial cells. Molecular and cellular endocrinology. 2021 03; 523(?):111149. doi: 10.1016/j.mce.2020.111149. [PMID: 33387601]
  • Stefanie Liening, Jana Fischer, Hans Jagusch, Georg Pohnert, Oliver Höcker, Christian Neusüß, Oliver Werz, Gerhard K E Scriba, Ulrike Garscha. 12-Oxo-10-glutathionyl-5,8,14-eicosatrienoic acid (TOG10), a novel glutathione-containing eicosanoid generated via the 12-lipoxygenase pathway in human platelets. Prostaglandins & other lipid mediators. 2021 02; 152(?):106480. doi: 10.1016/j.prostaglandins.2020.106480. [PMID: 33172790]
  • Naoaki Matsuo, Toru Miyoshi, Atsushi Takaishi, Takao Kishinoue, Kentaro Yasuhara, Masafumi Tanimoto, Yukari Nakano, Nobuhiko Onishi, Masayuki Ueeda, Hiroshi Ito. High Plasma Docosahexaenoic Acid Associated to Better Prognoses of Patients with Acute Decompensated Heart Failure with Preserved Ejection Fraction. Nutrients. 2021 Jan; 13(2):. doi: 10.3390/nu13020371. [PMID: 33530352]
  • Tomoaki Okada, Toru Miyoshi, Masayuki Doi, Kosuke Seiyama, Wataru Takagi, Masahiro Sogo, Kazumasa Nosaka, Masahiko Takahashi, Keisuke Okawa, Hiroshi Ito. Secular Decreasing Trend in Plasma Eicosapentaenoic and Docosahexaenoic Acids among Patients with Acute Coronary Syndrome from 2011 to 2019: A Single Center Descriptive Study. Nutrients. 2021 Jan; 13(1):. doi: 10.3390/nu13010253. [PMID: 33477264]
  • Zhe Jiang, Takuya Hayashi, Kentaro Kashima, Kayo Kurotani, Bungo Shirouchi, Tetsuya Mizoue, Masao Sato. Alteration of Serum Phospholipid n-6 Polyunsaturated Fatty Acid Compositions in Nonalcoholic Fatty Liver Disease in the Japanese Population: A Cross-Sectional Study. Lipids. 2020 11; 55(6):599-614. doi: 10.1002/lipd.12251. [PMID: 32691411]
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  • Takahisa Mori, Kazuhiro Yoshioka, Yuhei Tanno, Shigen Kasakura. Association of Serum Fatty Acids at Admission with the Age of Onset of Intracerebral Hemorrhage. Nutrients. 2020 Sep; 12(10):. doi: 10.3390/nu12102903. [PMID: 32977415]
  • Ekaterina Novichkova, Katya Chumin, Noy Eretz-Kdosha, Sammy Boussiba, Jacob Gopas, Guy Cohen, Inna Khozin-Goldberg. DGLA from the Microalga Lobosphaera Incsa P127 Modulates Inflammatory Response, Inhibits iNOS Expression and Alleviates NO Secretion in RAW264.7 Murine Macrophages. Nutrients. 2020 Sep; 12(9):. doi: 10.3390/nu12092892. [PMID: 32971852]
  • Souha Hammouda, Imen Ghzaiel, Wided Khamlaoui, Sonia Hammami, Samia Younes Mhenni, Slim Samet, Mohamed Hammami, Amira Zarrouk. Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population. Prostaglandins, leukotrienes, and essential fatty acids. 2020 09; 160(?):102159. doi: 10.1016/j.plefa.2020.102159. [PMID: 32682282]
  • Marcos A Perez, Leslie Magtanong, Scott J Dixon, Jennifer L Watts. Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells. Developmental cell. 2020 08; 54(4):447-454.e4. doi: 10.1016/j.devcel.2020.06.019. [PMID: 32652074]
  • Takahisa Mori, Kazuhiro Yoshioka, Yuhei Tanno, Shigen Kasakura. Association of Serum Fatty Acids at Admission with the Age of Onset of Acute Ischemic Stroke. Nutrients. 2020 Aug; 12(8):. doi: 10.3390/nu12082411. [PMID: 32806540]
  • Hugo F Olivares-Rubio, J J Espinosa-Aguirre. Role of epoxyeicosatrienoic acids in the lung. Prostaglandins & other lipid mediators. 2020 08; 149(?):106451. doi: 10.1016/j.prostaglandins.2020.106451. [PMID: 32294527]
  • Kodai Ishihara, Kazuhiro P Izawa, Masahiro Kitamura, Takayuki Shimogai, Yuji Kanejima, Tomoyuki Morisawa, Ikki Shimizu. Serum concentration of dihomo-γ-linolenic acid is associated with cognitive function and mild cognitive impairment in coronary artery disease patients. Prostaglandins, leukotrienes, and essential fatty acids. 2020 07; 158(?):102038. doi: 10.1016/j.plefa.2019.102038. [PMID: 31767440]
  • John D Imig, Wojciech K Jankiewicz, Abdul H Khan. Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture. Hypertension (Dallas, Tex. : 1979). 2020 07; 76(1):3-15. doi: 10.1161/hypertensionaha.120.13898. [PMID: 32475311]
  • Cuiping Zhang, Zuojian Hu, Ke Wang, Lujie Yang, Yue Li, Hartmut Schlüter, Pengyuan Yang, Jiaxu Hong, Hongxiu Yu. Lipidomic profiling of virus infection identifies mediators that resolve herpes simplex virus-induced corneal inflammatory lesions. The Analyst. 2020 Jun; 145(11):3967-3976. doi: 10.1039/d0an00263a. [PMID: 32319474]
  • Ming-Xiao Wang, Li-Jun Wang, Yu Xiao, Dan-Dan Zhang, Xin-Peng Duan, Wen-Hui Wang. Epoxyeicosatrienoic acid metabolites inhibit Kir4.1/Kir5.1 in the distal convoluted tubule. American journal of physiology. Renal physiology. 2020 06; 318(6):F1369-F1376. doi: 10.1152/ajprenal.00018.2020. [PMID: 32308018]
  • Susan Sergeant, Brian Hallmark, Rasika A Mathias, Tammy L Mustin, Priscilla Ivester, Maggie L Bohannon, Ingo Ruczinski, Laurel Johnstone, Michael C Seeds, Floyd H Chilton. Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and ɣ-linolenic acid-containing botanical oils. The American journal of clinical nutrition. 2020 05; 111(5):1068-1078. doi: 10.1093/ajcn/nqaa023. [PMID: 32167131]
  • Mercè Pallàs, Santiago Vázquez, Coral Sanfeliu, Carles Galdeano, Christian Griñán-Ferré. Soluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy. Biomolecules. 2020 05; 10(5):. doi: 10.3390/biom10050703. [PMID: 32369955]
  • Marco Rahm, Juliane Merl-Pham, Jerzy Adamski, Stefanie M Hauck. Time-resolved phosphoproteomic analysis elucidates hepatic 11,12-Epoxyeicosatrienoic acid signaling pathways. Prostaglandins & other lipid mediators. 2020 02; 146(?):106387. doi: 10.1016/j.prostaglandins.2019.106387. [PMID: 31669255]
  • Carolina Shene, Paris Paredes, Daniela Vergara, Allison Leyton, Marcelo Garcés, Liset Flores, Mónica Rubilar, Mariela Bustamante, Roberto Armenta. Antarctic thraustochytrids: Producers of long-chain omega-3 polyunsaturated fatty acids. MicrobiologyOpen. 2020 01; 9(1):e00950. doi: 10.1002/mbo3.950. [PMID: 31637873]
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  • Walter Adams, Rudra Bhowmick, Elsa N Bou Ghanem, Kristin Wade, Mikhail Shchepetov, Jeffrey N Weiser, Beth A McCormick, Rodney K Tweten, John M Leong. Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Streptococcus pneumoniae Infection. Journal of immunology (Baltimore, Md. : 1950). 2020 01; 204(1):101-111. doi: 10.4049/jimmunol.1800748. [PMID: 31776202]
  • Yi-Min Kuo, Pei-Chien Hsu, Chia-Chi Hung, Ya-Yu Hu, Yu-Jie Huang, Yu-Ling Gan, Chun-Hua Lin, Feng-Shiun Shie, Wen-Kuei Chang, Lung-Sen Kao, Mei-Yung Tsou, Yi-Hsuan Lee. Soluble Epoxide Hydrolase Inhibition Attenuates Excitotoxicity Involving 14,15-Epoxyeicosatrienoic Acid-Mediated Astrocytic Survival and Plasticity to Preserve Glutamate Homeostasis. Molecular neurobiology. 2019 Dec; 56(12):8451-8474. doi: 10.1007/s12035-019-01669-8. [PMID: 31257558]
  • Uwe Hoff, Gordana Bubalo, Mandy Fechner, Maximilian Blum, Ye Zhu, Andreas Pohlmann, Jan Hentschel, Karen Arakelyan, Erdmann Seeliger, Bert Flemming, Dennis Gürgen, Michael Rothe, Thoralf Niendorf, Vijaya L Manthati, John R Falck, Michael Haase, Wolf-Hagen Schunck, Duska Dragun. A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury. Acta physiologica (Oxford, England). 2019 10; 227(2):e13297. doi: 10.1111/apha.13297. [PMID: 31077555]
  • Boye L Jensen. Protection against acute kidney injury is afforded by a 14,15-epoxy-eicosatrienoic acid (EET) analog-A potential druggable pathway. Acta physiologica (Oxford, England). 2019 10; 227(2):e13330. doi: 10.1111/apha.13330. [PMID: 31177630]
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