aspirin (BioDeep_00000405475)

Main id: BioDeep_00000002166

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Acetylsaliycilic acid

化学式: C9H8O4 (180.0423)
中文名称: 乙酰水杨酸, 阿司匹林
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)Oc(c1)c(ccc1)C(O)=O
InChI: InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

描述信息

B - Blood and blood forming organs > B01 - Antithrombotic agents > B01A - Antithrombotic agents > B01AC - Platelet aggregation inhibitors excl. heparin
N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BA - Salicylic acid and derivatives
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
A - Alimentary tract and metabolism > A01 - Stomatological preparations > A01A - Stomatological preparations
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor > C287 - Aspirin
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D002491 - Central Nervous System Agents > D000700 - Analgesics
D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents
D050299 - Fibrin Modulating Agents
D002317 - Cardiovascular Agents
D004791 - Enzyme Inhibitors
D058633 - Antipyretics
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
CONFIDENCE standard compound; INTERNAL_ID 112

同义名列表

5 个代谢物同义名

aspirin; Acetylsaliycilic acid; Acetylsalicylic acid; Aspirin; Aspirin



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(2)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ACE, ALOX5, NFKB1, NOS3, PF4, PTGS2, VASP, VEGFA
Peripheral membrane protein 2 ALOX5, PTGS2
Endoplasmic reticulum membrane 3 HMGCR, PROS1, PTGS2
Nucleus 3 NFKB1, NOS3, VEGFA
cytosol 4 ALOX5, NFKB1, NOS3, VASP
dendrite 1 P2RY1
nucleoplasm 3 ALOX5, NFKB1, NOS3
Cell membrane 4 ACE, CYSLTR2, ITGAM, P2RY1
lamellipodium 1 VASP
Multi-pass membrane protein 3 CYSLTR2, HMGCR, P2RY1
cell surface 5 EPO, ITGA2B, ITGAM, P2RY1, VEGFA
glutamatergic synapse 2 P2RY1, VASP
Golgi apparatus 2 NOS3, VEGFA
Golgi membrane 2 NOS3, PROS1
postsynapse 1 VASP
Cytoplasm, cytosol 1 ALOX5
Lysosome 1 ACE
endosome 1 ACE
plasma membrane 11 ACE, CYSLTR1, CYSLTR2, IFNLR1, ITGA2B, ITGAM, KNG1, NOS3, P2RY1, PROS1, VASP
Membrane 7 ACE, CYSLTR1, HMGCR, IFNLR1, ITGA2B, ITGAM, VEGFA
apical plasma membrane 1 P2RY1
basolateral plasma membrane 1 P2RY1
caveola 2 NOS3, PTGS2
extracellular exosome 8 ACE, EPO, ITGA2B, ITGAM, KNG1, PROS1, VASP, VWF
endoplasmic reticulum 5 HMGCR, PROS1, PTGS2, VEGFA, VWF
extracellular space 10 ACE, ALOX5, CRP, EPO, ITGAM, KNG1, PF4, PROS1, VEGFA, VWF
perinuclear region of cytoplasm 2 ALOX5, NOS3
Cell junction, tight junction 1 VASP
adherens junction 1 VEGFA
bicellular tight junction 1 VASP
mitochondrion 1 NFKB1
protein-containing complex 1 PTGS2
Microsome membrane 1 PTGS2
filopodium 1 VASP
postsynaptic density 1 P2RY1
Single-pass type I membrane protein 4 ACE, IFNLR1, ITGA2B, ITGAM
Secreted 7 ACE, CRP, EPO, PF4, PROS1, VEGFA, VWF
extracellular region 10 ACE, ALOX5, CRP, EPO, KNG1, NFKB1, PF4, PROS1, VEGFA, VWF
transcription regulator complex 1 NFKB1
Nucleus membrane 1 ALOX5
nuclear membrane 1 ALOX5
external side of plasma membrane 3 ACE, ITGA2B, ITGAM
Secreted, extracellular space, extracellular matrix 2 VEGFA, VWF
actin cytoskeleton 1 VASP
Cytoplasm, P-body 1 NOS3
P-body 1 NOS3
postsynaptic membrane 1 P2RY1
presynaptic active zone membrane 1 P2RY1
Cell projection, lamellipodium 1 VASP
Cytoplasm, perinuclear region 1 ALOX5
Membrane raft 1 ITGAM
Cytoplasm, cytoskeleton 1 VASP
focal adhesion 2 ITGA2B, VASP
extracellular matrix 2 VEGFA, VWF
peroxisomal membrane 1 HMGCR
collagen-containing extracellular matrix 3 KNG1, PF4, VWF
secretory granule 1 VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
cilium 1 P2RY1
chromatin 1 NFKB1
cell projection 1 VASP
cytoskeleton 2 NOS3, VASP
Secreted, extracellular space 1 KNG1
brush border membrane 1 ACE
blood microparticle 3 ITGA2B, KNG1, PROS1
sperm midpiece 1 ACE
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
Cytoplasm, Stress granule 1 NOS3
cytoplasmic stress granule 1 NOS3
cell body 2 EPO, P2RY1
Peroxisome membrane 1 HMGCR
filopodium membrane 1 VASP
basal plasma membrane 1 ACE
platelet alpha granule 1 VWF
plasma membrane raft 1 ITGAM
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 3 ALOX5, EPO, NFKB1
Golgi lumen 1 PROS1
endoplasmic reticulum lumen 2 KNG1, PTGS2
nuclear matrix 1 ALOX5
platelet alpha granule lumen 5 KNG1, PF4, PROS1, VEGFA, VWF
specific granule lumen 1 NFKB1
endocytic vesicle membrane 1 NOS3
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
platelet alpha granule membrane 1 ITGA2B
integrin complex 2 ITGA2B, ITGAM
lamellipodium membrane 1 VASP
Weibel-Palade body 1 VWF
integrin alphaIIb-beta3 complex 1 ITGA2B
integrin alphaM-beta2 complex 1 ITGAM
Nucleus intermembrane space 1 ALOX5
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
[Nuclear factor NF-kappa-B p105 subunit]: Cytoplasm 1 NFKB1
[Nuclear factor NF-kappa-B p50 subunit]: Nucleus 1 NFKB1
I-kappaB/NF-kappaB complex 1 NFKB1
NF-kappaB p50/p65 complex 1 NFKB1
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Jhony Robson de Oliveira, Aline Beatriz Mahler Pereira, Henrique Ismarsi de Souza, Wanessa Maria Dos Santos, Thaís Sorares Farnesi de Assunção, Fernanda Bernadelli de Vito, Helio Moraes de Souza, Paulo Roberto da Silva, Marcos Vinicius da Silva, Virmondes Rodrigues Junior, Alexandre Paula Rogerio. Anti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells stimulated by cigarette smoke extract. Prostaglandins & other lipid mediators. 2024 Jun; 172(?):106833. doi: 10.1016/j.prostaglandins.2024.106833. [PMID: 38460760]
  • Valery J Kogler, Jeffrey A Miles, Tahsin Özpolat, S Lawrence Bailey, Daire A Byrne, Morgan Bawcom-Randall, Yi Wang, Hannah J Larsen, Franklin Reed, Xiaoyun Fu, Moritz Stolla. Platelet dysfunction reversal with cold-stored vs room temperature-stored platelet transfusions. Blood. 2024 May; 143(20):2073-2088. doi: 10.1182/blood.2023022593. [PMID: 38427589]
  • Yuxin Wang, Wenwan Peng, Mingguo Dong. Letter: Bif195 for aspirin-induced gastric mucosal damage-More to do in further research. Alimentary pharmacology & therapeutics. 2024 May; 59(10):1304-1305. doi: 10.1111/apt.17984. [PMID: 38652764]
  • Hui-Sheng Chen, Yu Cui, Xin-Hong Wang, Yu-Tong Ma, Jing Han, Ying-Jie Duan, Jiang Lu, Li-Ying Shen, Yong Liang, Wei-Zhong Wang, Hui Wang, Yong Zhao, Jin-Tao Zhang, Yu-Lin Song, Xiao-Mei He, Run-Hui Li, Ding-Bo Tao, Jing Li, Shu-Man Huang, Ni Wang, Mei Hong, Chong Meng, Wei Zhang, Duo-Lao Wang, Thanh N Nguyen. Clopidogrel Plus Aspirin vs Aspirin Alone in Patients With Acute Mild to Moderate Stroke: The ATAMIS Randomized Clinical Trial. JAMA neurology. 2024 May; 81(5):450-460. doi: 10.1001/jamaneurol.2024.0146. [PMID: 38466274]
  • Jiao Liu, Lixia Shen, Long Nguyen-Hoang, Qiongjie Zhou, Chi Chiu Wang, Xiaohong Lu, Daljit Sahota, Ka Chun Chong, Hao Ying, Weirong Gu, Rong Zhou, Huixia Yang, Yanmin Jiang, Dunjin Chen, Xiaotian Li, Liona Poon. Aspirin versus metformin in pregnancies at high risk of preterm pre-eclampsia in China (AVERT): protocol for a multicentre, double-blind, 3-arm randomised controlled trial. BMJ open. 2024 Apr; 14(4):e074493. doi: 10.1136/bmjopen-2023-074493. [PMID: 38631826]
  • Sun Linjuan, L I Chengfu, Liu Jiangang, L I Nannan, Han Fuhua, Qiao Dandan, Tao Zhuang, Zhan Min, Chen Wenjie, Zhang Xiaohui, Tong Chenguang, Chen Dong, Qi Jiangxia, Liu Yang, Liang Xiao, Zheng Xiaoying, Zhang Yunling. Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2024 Apr; 44(2):289-302. doi: 10.19852/j.cnki.jtcm.20240203.007. [PMID: 38504535]
  • Ting Chen, Juan Chen, Sheng-Chuan Bao, Jia-Xiang Zhang, Hai-Liang Wei, Xiao-Yan Zhou, Xin Hu, Yan Liang, Jing-Tao Li, Shu-Guang Yan. Mechanism of Xiaojianzhong decoction in alleviating aspirin-induced gastric mucosal injury revealed by transcriptomics and metabolomics. Journal of ethnopharmacology. 2024 Jan; 318(Pt A):116910. doi: 10.1016/j.jep.2023.116910. [PMID: 37453623]
  • Shiqi Yuan, Yitong Ling, Xiaxuan Huang, Shanyuan Tan, Wanyue Li, Anding Xu, Jun Lyu. Associations between the use of common nonsteroidal anti-inflammatory drugs, genetic susceptibility and dementia in participants with chronic pain: A prospective study based on 194,758 participants from the UK Biobank. Journal of psychiatric research. 2024 01; 169(?):152-159. doi: 10.1016/j.jpsychires.2023.11.030. [PMID: 38039689]
  • Xiaofei Guo, Shuxian Zheng, Yong Zhi. Comment on 'The role of aspirin versus low-molecular-weight heparin for venous thromboembolism prophylaxis after total knee arthroplasty: a meta-analysis of randomized controlled trials'. International journal of surgery (London, England). 2024 Jan; 110(1):621-622. doi: 10.1097/js9.0000000000000825. [PMID: 37800552]
  • Li-Na Li, Xiao-Dan Li, Juan Du. The effect of aspirin on uterine arterial blood flow and endometrium in moderate and severe intrauterine adhesion after transcervical resection of adhesion: a systematic review and meta-analysis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2023 Dec; 36(1):2209818. doi: 10.1080/14767058.2023.2209818. [PMID: 37286223]
  • Samapika Sahu, Harish Srinivasan, Sankalp E Jadhav, Veerendra K Sharma, Ananya Debnath. Aspirin-Induced Ordering and Faster Dynamics of a Cationic Bilayer for Drug Encapsulation. Langmuir : the ACS journal of surfaces and colloids. 2023 11; 39(46):16432-16443. doi: 10.1021/acs.langmuir.3c02241. [PMID: 37948158]
  • Michael Krmic, Escarlin Perez, Patrick Scollan, Katherine Ivanchenko, Alondra Gamez Hernandez, Joseph Giancaspro, Juan Rosario, Jasmin Ceja-Vega, Jamie Gudyka, Riley Porteus, Sunghee Lee. Aspirin Interacts with Cholesterol-Containing Membranes in a pH-Dependent Manner. Langmuir : the ACS journal of surfaces and colloids. 2023 Nov; ?(?):. doi: 10.1021/acs.langmuir.3c02242. [PMID: 37939382]
  • Mariana Garrido-Valdes, Leonor Díaz-Velis, Marisela Valdes-Gonzalez, Barbara B Garrido-Suárez, Gabino Garrido. Gastroprotective Role of Fruit Extracts in Gastric Damage Induced by Non-Steroidal Anti-Inflammatory Drugs: A Systematic Review. Journal of medicinal food. 2023 Nov; 26(11):777-798. doi: 10.1089/jmf.2023.0005. [PMID: 37902784]
  • Fan Xia, Li-Sha Lin, Yan-Song Ye, Lian Yang, Jin-Hua Zhao, Gang Xu. 11,12-seco-Abietane-type diterpene lactones with potential antiplatelet activity from Salvia prattii. Bioorganic chemistry. 2023 11; 140(?):106834. doi: 10.1016/j.bioorg.2023.106834. [PMID: 37677855]
  • John R Davies, Tracey Mell, Harriett Fuller, Mark Harland, Rasha Nm Saleh, Amanda D Race, Colin J Rees, Louise C Brown, Paul M Loadman, Amy Downing, Anne Marie Minihane, Elizabeth A Williams, Mark A Hull. Polymorphisms in Cyclooxygenase, Lipoxygenase and TP53 genes predict colorectal polyp risk reduction by aspirin in the seAFOod polyp prevention trial. Cancer prevention research (Philadelphia, Pa.). 2023 Sep; ?(?):. doi: 10.1158/1940-6207.capr-23-0111. [PMID: 37756582]
  • Ahmed Sayed, Malak Munir, Daniel Addison, Abdelrahman I Abushouk, Susan F Dent, Tomas G Neilan, Anne Blaes, Michael G Fradley, Anju Nohria, Khaled Moustafa, Salim S Virani. The underutilization of preventive cardiovascular measures in patients with cancer: an analysis of the Behavioural Risk Factor Surveillance System, 2011-22. European journal of preventive cardiology. 2023 09; 30(13):1325-1332. doi: 10.1093/eurjpc/zwad146. [PMID: 37158488]
  • Anete Kaldal, Serena Tonstad, Jarle Jortveit. Sex differences in secondary preventive follow-up after coronary heart events. BMC cardiovascular disorders. 2023 09; 23(1):459. doi: 10.1186/s12872-023-03483-6. [PMID: 37710178]
  • Junxi Chi, Jiahao Cheng, Shang Wang, Cheng Li, Ming Chen. Promising Anti-Inflammatory Tools: Biomedical Efficacy of Lipoxins and Their Synthetic Pathways. International journal of molecular sciences. 2023 Aug; 24(17):. doi: 10.3390/ijms241713282. [PMID: 37686088]
  • Caroline Nb Clezar, Carolina Dq Flumignan, Nicolle Cassola, Luis Cu Nakano, Virginia Fm Trevisani, Ronald Lg Flumignan. Pharmacological interventions for asymptomatic carotid stenosis. The Cochrane database of systematic reviews. 2023 Aug; 8(?):CD013573. doi: 10.1002/14651858.cd013573.pub2. [PMID: 37565307]
  • Jana H Badrani, Kellen Cavagnero, Jacqueline J Eastman, Alex S Kim, Allyssa Strohm, Carol Yan, Adam Deconde, Bruce L Zuraw, Andrew A White, Sandra C Christiansen, Taylor A Doherty. Lower serum 15-HETE predicts nasal ILC2 accumulation during COX-1 inhibition in AERD. The Journal of allergy and clinical immunology. 2023 Aug; ?(?):. doi: 10.1016/j.jaci.2023.06.028. [PMID: 37543185]
  • Cui-Cui Wang, Qing Zhao, Bing-Yan Guo, Jie Hao, Jia-Jia Zhao, Jia-Liang Ren, Ya-Qing Sun, Xiao-Rui Zhang, Xiu-Ling Yang, Jin-Ming Liu. The Plasma Concentration of Ticagrelor and Aspirin as a Predictor of Bleeding Complications in Chinese Acute Coronary Syndrome Patients With Dual Antiplatelet Therapy: A Prospective Observational Study. Journal of cardiovascular pharmacology. 2023 08; 82(2):148-156. doi: 10.1097/fjc.0000000000001442. [PMID: 37295072]
  • Qiuyue Li, Gulin Deng, Hong Xu, Jiazhen Yin, Rukui Yuan, Xinwu Huang, Guochun Li. Zhilong Huoxue Tongyu capsule ameliorates platelet aggregation and thrombus induced by aspirin in rats by regulating lipid metabolism and microRNA pathway. Combinatorial chemistry & high throughput screening. 2023 Jul; ?(?):. doi: 10.2174/1386207326666230712110103. [PMID: 37438906]
  • Joanna de Freitas Rocha, Letícia de Castro Viana, Luiz Carlos Pereira Almeida Filho, Thiago Silva de Almeida, José Joaquim Lopes Neto, Veríssimo Vieira Neto, Pedro Matheus Sousa Tabosa, Diana Célia Sousa Nunes-Pinheiro, Virgínia Cláudia Carneiro Girão-Carmona, Ana Fontenele Urano Carvalho, Erika Freitas Mota. In vitro anti-inflammatory activity and ameliorative effects on gastric ulcers of Licania rigida benth seed extract. Inflammopharmacology. 2023 Jul; ?(?):. doi: 10.1007/s10787-023-01283-0. [PMID: 37420144]
  • Valentina Burgess, Juan D Maya. Statin and aspirin use in parasitic infections as a potential therapeutic strategy: A narrative review. Revista Argentina de microbiologia. 2023 Jul; 55(3):278-288. doi: 10.1016/j.ram.2023.01.006. [PMID: 37019801]
  • Hui-Sheng Chen, Yu Cui, Zhong-He Zhou, Hong Zhang, Li-Xia Wang, Wei-Zhong Wang, Li-Ying Shen, Li-Yan Guo, Er-Qiang Wang, Rui-Xian Wang, Jing Han, Yu-Ling Dong, Jing Li, Yong-Zhong Lin, Qing-Cheng Yang, Li Zhang, Jing-Yu Li, Jin Wang, Lei Xia, Guang-Bin Ma, Jiang Lu, Chang-Hao Jiang, Shu-Man Huang, Li-Shu Wan, Xiang-Yu Piao, Zhuo Li, Yan-Song Li, Kui-Hua Yang, Duo-Lao Wang, Thanh N Nguyen. Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial. JAMA. 2023 06; 329(24):2135-2144. doi: 10.1001/jama.2023.7827. [PMID: 37367978]
  • Wenjie Zi, Jiaxing Song, Weilin Kong, Jiacheng Huang, Changwei Guo, Wencheng He, Yinquan Yu, Bo Zhang, Wanjie Geng, Xiaolin Tan, Yaoyu Tian, Zongtao Liu, Minghua Cao, Daoyou Cheng, Bo Li, Wenguo Huang, Junsheng Liu, Pengfei Wang, Zhou Yu, Hao Liang, Shuang Yang, Mingshan Tang, Wenhua Liu, Xianjun Huang, Shugai Liu, Yufeng Tang, Youlin Wu, Li Yao, Zhu Shi, Pengcheng He, Haojin Zhao, Zhuo Chen, Jun Luo, Yue Wan, Qiang Shi, Maorong Wang, De Yang, Xianglin Chen, Fang Huang, Jinlin Mu, Hao Li, Zhimin Li, Jingbang Zheng, Shunli Xie, Tieying Cai, Yuqi Peng, Weihua Xie, Zhongming Qiu, Chang Liu, Chengsong Yue, Linyu Li, Yan Tian, Dahong Yang, Jian Miao, Jie Yang, Jinrong Hu, Raul G Nogueira, Duolao Wang, Jeffrey L Saver, Fengli Li, Qingwu Yang. Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion. The New England journal of medicine. 2023 Jun; 388(22):2025-2036. doi: 10.1056/nejmoa2214299. [PMID: 37256974]
  • Whitney W Stevens, Katherine N Cahill. Mechanistic and clinical updates in AERD: 2021-2022. The Journal of allergy and clinical immunology. 2023 06; 151(6):1448-1456. doi: 10.1016/j.jaci.2023.03.015. [PMID: 36967016]
  • Yuesong Pan, Xia Meng, Baoshi Yuan, S Claiborne Johnston, Hao Li, Philip M Bath, Qiang Dong, Anding Xu, Jing Jing, Jinxi Lin, Yong Jiang, Xuewei Xie, Aoming Jin, Yue Suo, Hongqin Yang, Yefang Feng, Yanhua Zhou, Qing Liu, Xueli Li, Bin Liu, Hui Zhu, Jinguo Zhao, Xuerong Huang, Haitao Li, Yunyun Xiong, Zixiao Li, Yilong Wang, Xingquan Zhao, Liping Liu, Yongjun Wang. Indobufen versus aspirin in patients with acute ischaemic stroke in China (INSURE): a randomised, double-blind, double-dummy, active control, non-inferiority trial. The Lancet. Neurology. 2023 06; 22(6):485-493. doi: 10.1016/s1474-4422(23)00113-8. [PMID: 37121237]
  • Ying Dong, Xiao Li, Yicheng Zhao, Xueyang Ren, Yuan Zheng, Ruolan Song, Xiangjian Zhong, Dongjie Shan, Fang Lv, Qingyue Deng, Xianxian Li, Yingyu He, Keyan Chai, Xiuhuan Wang, Gaimei She. Biotransformation and metabolism of three methyl salicylate glycosides by gut microbiota in vitro. Journal of pharmaceutical and biomedical analysis. 2023 May; 233(?):115474. doi: 10.1016/j.jpba.2023.115474. [PMID: 37229798]
  • Basma M Bawish, Mariem A Rabab, Safaa T Gohari, Marwa S Khattab, Naglaa A AbdElkader, Samar H Elsharkawy, Amr M Ageez, Manal M Zaki, Shaimaa Kamel, Eman M Ismail. Promising effect of Geranium robertianum L. leaves and Aloe vera gel powder on Aspirin®-induced gastric ulcers in Wistar rats: anxiolytic behavioural effect, antioxidant activity, and protective pathways. Inflammopharmacology. 2023 May; ?(?):. doi: 10.1007/s10787-023-01205-0. [PMID: 37184667]
  • Zhixia Bai, Yajuan Liu, Yang Zhao, Ru Yan, Libo Yang, Huiyan Ma, Jing Wang, Ting Wang, Yiwei Li, Guoshan Zhang, Xiaoxia Zhang, Shaobin Jia, Hao Wang. Aspirin ameliorates atherosclerotic immuno-inflammation through regulating the Treg/Th17 axis and CD39-CD73 adenosine signaling via remodeling the gut microbiota in ApoE-/- mice. International immunopharmacology. 2023 May; 120(?):110296. doi: 10.1016/j.intimp.2023.110296. [PMID: 37187127]
  • Tuhina Gayen, Anchal Tripathi, Usha Kumari, Swati Mittal, Ajay Kumar Mittal. Ecotoxicological impacts of environmentally relevant concentrations of aspirin in the liver of Labeo rohita: Biochemical and histopathological investigation. Chemosphere. 2023 May; 333(?):138921. doi: 10.1016/j.chemosphere.2023.138921. [PMID: 37178937]
  • Chunxiang Chen, Huihui Lv, Lili Shan, Xie Long, Cen Guo, Yajing Huo, Lingdan Lu, Yinting Zhou, Mingyuan Liu, Haibo Wu, Desheng Zhu, Yan Han. Antiplatelet effect of ginkgo diterpene lactone meglumine injection in acute ischemic stroke: A randomized, double-blind, placebo-controlled clinical trial. Phytotherapy research : PTR. 2023 May; 37(5):1986-1996. doi: 10.1002/ptr.7720. [PMID: 36609866]
  • Daniel J Stephenson, H Patrick MacKnight, L Alexis Hoeferlin, Sonya L Washington, Chelsea Sawyers, Kellie J Archer, Jerome F Strauss, Scott W Walsh, Charles E Chalfant. Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy. Journal of lipid research. 2023 Apr; ?(?):100377. doi: 10.1016/j.jlr.2023.100377. [PMID: 37119922]
  • Line Philipsen, Nanna Würtz, Christoffer Polcwiartek, Kristian Hay Kragholm, Christian Torp-Pedersen, Rene Ernst Nielsen, Svend Eggert Jensen, Rubina Attar. Time trends of coronary procedures, guideline-based drugs and all-cause mortality following acute coronary syndrome in patients with bipolar disorder. Nordic journal of psychiatry. 2023 Apr; 77(3):304-311. doi: 10.1080/08039488.2022.2102208. [PMID: 35904234]
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