Shogaol (BioDeep_00000229873)

 

Secondary id: BioDeep_00000002771, BioDeep_00000872291

natural product PANOMIX_OTCML-2023 Chemicals and Drugs Antitumor activity


代谢物信息卡片


4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (4E)-

化学式: C17H24O3 (276.1725)
中文名称: 姜烯酚, 6-姜烯酚
谱图信息: 最多检出来源 Viridiplantae(plant) 6.69%

分子结构信息

SMILES: CCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1
InChI: InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+

描述信息

[6]-Shogaol is a monomethoxybenzene, a member of phenols and an enone.
Shogaol is a natural product found in Flueggea suffruticosa, Zingiber zerumbet, and other organisms with data available.
See also: Ginger (part of).
C1907 - Drug, Natural Product > C28269 - Phytochemical
D009676 - Noxae > D009153 - Mutagens
Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

同义名列表

36 个代谢物同义名

4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (4E)-; 1-(4-Hydroxy-3-methoxyphenyl)-4-dodecen-3-one, 9CI; [(E)-1-(4-hydroxy-3-methoxyphenyl)-dec-4-en-3-one]; 4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (E); (E)-1-(4-Hydroxy-3-methoxy-phenyl)-dec-4-en-3-one; (E)-1-(4-Hydroxy-3- methoxyphenyl)dec-4-en-3-one; (4E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one; (E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one; 4-DECEN-3-ONE, 1-(4-HYDROXY-3-METHOXYPHENYL)-; 4-Decen-3-one, 1-(4-hydroxy-3-methoxyphenyl); 1-(4-Hydroxy-3-methoxyphenyl)-4-decen-3-one; 1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one; 6-Shogaol (constituent of ginger) [DSC]; 6-Shogaol (constituent of ginger); [6]-Shogaol, analytical standard; trans-6-Shogaol;(E)-[6]-Shogaol; Shogaol, >=90\\% (HPLC); [6]-Shogaol;6-Shogaol; Shogaol (6-Shogaol); ENEXASOGAOL [INN]; Trans-6-Shogaol; UNII-83DNB5FIRF; MEGxp0_001217; ACon1_001190; [6]-Shogaol; (6)-shogaol; enexasogaol; 83DNB5FIRF; 6-Shogaol; Shogaol; (E)-1-(4-hydroxy-3-methoxy-phenyl)dec-4-en-3-one; 1-(4-hydroxy-3-methoxy-phenyl)dec-4-en-3-one; CCRIS 2038; 555-66-8; C10494; [6]-Shogaol



数据库引用编号

35 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

70 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 15 AKT1, BCL2, BDNF, CASP3, KEAP1, MAPK14, MAPK8, MTOR, NFE2L2, NOS2, PIK3CA, PTGS2, STAT3, TLR4, TP53
Peripheral membrane protein 3 GORASP1, MTOR, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 4 BCL2, HMOX1, MTOR, PTGS2
Nucleus 12 AKT1, BCL2, CASP3, HMOX1, KEAP1, MAPK14, MAPK8, MTOR, NFE2L2, NOS2, STAT3, TP53
cytosol 13 AKT1, BCL2, CASP3, HMOX1, KEAP1, MAPK14, MAPK8, MTOR, NFE2L2, NOS2, PIK3CA, STAT3, TP53
dendrite 2 BDNF, MTOR
phagocytic vesicle 1 MTOR
centrosome 2 NFE2L2, TP53
nucleoplasm 11 AKT1, CASP3, HMOX1, KEAP1, MAPK14, MAPK8, MTOR, NFE2L2, NOS2, STAT3, TP53
RNA polymerase II transcription regulator complex 2 NFE2L2, STAT3
Cell membrane 3 AKT1, TLR4, TNF
Cytoplasmic side 3 GORASP1, HMOX1, MTOR
lamellipodium 2 AKT1, PIK3CA
Golgi apparatus membrane 2 GORASP1, MTOR
Synapse 2 MAPK8, TAC1
cell cortex 1 AKT1
cell surface 2 TLR4, TNF
glutamatergic synapse 3 AKT1, CASP3, MAPK14
Golgi apparatus 2 GORASP1, NFE2L2
Golgi membrane 2 GORASP1, MTOR
lysosomal membrane 1 MTOR
neuronal cell body 3 CASP3, TAC1, TNF
postsynapse 1 AKT1
synaptic vesicle 1 BDNF
Cytoplasm, cytosol 2 NFE2L2, NOS2
Lysosome 1 MTOR
plasma membrane 7 AKT1, NFE2L2, NOS2, PIK3CA, STAT3, TLR4, TNF
Membrane 7 AKT1, BCL2, BDNF, HMOX1, MTOR, TLR4, TP53
axon 3 BDNF, MAPK8, TAC1
caveola 1 PTGS2
Lysosome membrane 1 MTOR
endoplasmic reticulum 5 BCL2, HMOX1, KEAP1, PTGS2, TP53
extracellular space 5 BDNF, HMOX1, IL6, TAC1, TNF
perinuclear region of cytoplasm 5 BDNF, HMOX1, NOS2, PIK3CA, TLR4
intercalated disc 1 PIK3CA
mitochondrion 3 BCL2, MAPK14, TP53
protein-containing complex 4 AKT1, BCL2, PTGS2, TP53
Microsome membrane 2 MTOR, PTGS2
postsynaptic density 1 CASP3
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 1 TLR4
Secreted 2 BDNF, IL6
extracellular region 5 BDNF, IL6, MAPK14, TAC1, TNF
Mitochondrion outer membrane 2 BCL2, MTOR
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 3 BCL2, HMOX1, MTOR
Mitochondrion matrix 1 TP53
mitochondrial matrix 1 TP53
transcription regulator complex 2 STAT3, TP53
centriolar satellite 1 KEAP1
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 TP53
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 2 TLR4, TNF
microtubule cytoskeleton 1 AKT1
nucleolus 1 TP53
midbody 1 KEAP1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Early endosome 1 TLR4
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton 1 TP53
spindle 1 AKT1
cis-Golgi network 1 GORASP1
Peroxisome 1 NOS2
peroxisomal matrix 1 NOS2
Nucleus, PML body 2 MTOR, TP53
PML body 2 MTOR, TP53
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
nuclear speck 1 MAPK14
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
chromatin 3 NFE2L2, STAT3, TP53
mediator complex 1 NFE2L2
phagocytic cup 2 TLR4, TNF
spindle pole 1 MAPK14
actin filament 1 KEAP1
site of double-strand break 1 TP53
Cul3-RING ubiquitin ligase complex 1 KEAP1
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
germ cell nucleus 1 TP53
replication fork 1 TP53
myelin sheath 1 BCL2
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 MAPK14
secretory granule lumen 1 MAPK14
endoplasmic reticulum lumen 3 BDNF, IL6, PTGS2
nuclear matrix 1 TP53
transcription repressor complex 1 TP53
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
Single-pass type IV membrane protein 1 HMOX1
[Isoform 1]: Nucleus 1 TP53
protein-DNA complex 1 NFE2L2
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, phagosome 1 MTOR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
cortical cytoskeleton 1 NOS2
inclusion body 1 KEAP1
interleukin-6 receptor complex 1 IL6
BAD-BCL-2 complex 1 BCL2
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Yoon-Tae Kim, Jae-Sung Shin, Sang-Jin Ye, Ji Hye Kim, Seok Hyun Eom, Moo-Yeol Baik. Conversion of gingerols to shogaols in ginger (Zingiber officinale roscoe) by puffing. Food chemistry. 2024 Sep; 452(?):139425. doi: 10.1016/j.foodchem.2024.139425. [PMID: 38744128]
  • Xiao-Lan Cheng, Yong-Lan Ruan, Jing-Ya Dai, Hai-Zhen Fan, Jin-Ying Ling, Jiao Chen, Wu-Guang Lu, Xue-Jiao Gao, Peng Cao. 8-shogaol derived from dietary ginger alleviated acute and inflammatory pain by targeting TRPV1. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155500. doi: 10.1016/j.phymed.2024.155500. [PMID: 38484627]
  • Kitti Pázmándi, Beatrix Ágics, Attila Gábor Szöllősi, Attila Bácsi, Tünde Fekete. Ginger-derived bioactive compounds attenuate the Toll-like receptor mediated responses of human dendritic cells. European journal of pharmacology. 2024 Mar; 967(?):176399. doi: 10.1016/j.ejphar.2024.176399. [PMID: 38331338]
  • Ah Young Yang, Kiryeong Kim, Hyun Hee Kwon, Jaechan Leem, Jeong Eun Song. 6-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress. Molecules (Basel, Switzerland). 2024 Jan; 29(2):. doi: 10.3390/molecules29020419. [PMID: 38257332]
  • Mirjana Sulejmanović, Nataša Milić, Ioannis Mourtzinos, Nataša Nastić, Anastasia Kyriakoudi, Jovana Drljača, Senka Vidović. Ultrasound-assisted and subcritical water extraction techniques for maximal recovery of phenolic compounds from raw ginger herbal dust toward in vitro biological activity investigation. Food chemistry. 2023 Oct; 437(Pt 1):137774. doi: 10.1016/j.foodchem.2023.137774. [PMID: 37866343]
  • X Zong, Q Ding, X Liu, Q Liu, S Song, X Yan, Y Zhang. Preventive Effect of 6-shogaol on D-galactosamine Induced Hepatotoxicity Through NF-?B/MAPK Signaling Pathway in Rats. Physiological research. 2023 Aug; 72(4):445-454. doi: . [PMID: 37795887]
  • Shuang Pan, Yaming Li, Jinzhao Zhang. 6-Shogaol prevents benzo (A) pyrene-exposed lung carcinogenesis via modulating PRDX1-associated oxidative stress, inflammation, and proliferation in mouse models. Environmental toxicology. 2023 Aug; ?(?):. doi: 10.1002/tox.23946. [PMID: 37638803]
  • Wenlin Zhang, Yang Yang, Xuedong Zhu, Suyu Yang, Ximei Liao, Honglei Li, Zhexin Li, Qinhong Liao, Jianmin Tang, Guohua Zhao, Lin Wu. Integrated analyses of metabolomics and transcriptomics reveal the potential regulatory roles of long non-coding RNAs in gingerol biosynthesis. BMC genomics. 2023 Aug; 24(1):490. doi: 10.1186/s12864-023-09553-5. [PMID: 37633894]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
  • Bin Li, Yunxiang Wang, Xin Yuan, Guanting Liu, Yunpeng Diao, Jing Liu. 6-Shogaol from Dried Ginger Protects Against Intestinal Ischemia/Reperfusion by Inhibiting Cell Apoptosis via the BDNF/TrkB/PI3K/AKT Pathway. Molecular nutrition & food research. 2023 Apr; ?(?):e2200773. doi: 10.1002/mnfr.202200773. [PMID: 37118920]
  • Abdelbaset Mohamed Elasbali, Waleed Abu Al-Soud, Afnan Elayyan Mousa Elayyan, Ziad H Al-Oanzi, Hassan H Alhassan, Bashir M Mohamed, Hamad H Alanazi, Mohammad Saquib Ashraf, Shadman Moiz, Mitesh Patel, Mirav Patel, Mohd Adnan. Integrating network pharmacology approaches for the investigation of multi-target pharmacological mechanism of 6-shogaol against cervical cancer. Journal of biomolecular structure & dynamics. 2023 Mar; ?(?):1-17. doi: 10.1080/07391102.2023.2191719. [PMID: 36943780]
  • Wenya Jiao, Yaxin Sang, Xianghong Wang, Shuo Wang. Metabonomics and the gut microbiome analysis of the effect of 6-shogaol on improving obesity. Food chemistry. 2023 Mar; 404(Pt B):134734. doi: 10.1016/j.foodchem.2022.134734. [PMID: 36327507]
  • Shoujiao Peng, Shaopeng Yu, Junmin Zhang, Jiange Zhang. 6-Shogaol as a Novel Thioredoxin Reductase Inhibitor Induces Oxidative-Stress-Mediated Apoptosis in HeLa Cells. International journal of molecular sciences. 2023 Mar; 24(5):. doi: 10.3390/ijms24054966. [PMID: 36902397]
  • Kanta Keosaeng, Weerasak Songoen, Thitaree Yooboon, Vasakorn Bullangpoti, Wanchai Pluempanupat. Insecticidal activity of isolated gingerols and shogaols from Zingiber officinale Roscoe rhizomes against Spodoptera spp. (Lepidoptera: Noctuidae). Natural product research. 2023 Feb; 37(4):669-674. doi: 10.1080/14786419.2022.2078818. [PMID: 35608145]
  • Chang Yu Kan, Jing Xuan H'ng, Andy Goh, Frederick Smales, Eng Lai Tan, Shiming Zhang, Mallikarjuna Rao Pichika, Abhishek Parolia. Effect of Sustained Systemic Administration of Ginger (Z officinale) Rhizome Extracts on Salivary Flow in Mice. International dental journal. 2023 Feb; 73(1):63-70. doi: 10.1016/j.identj.2022.04.011. [PMID: 35725589]
  • Jiasheng Li, Ying Zhang, Shurui Liu, Wangjun Li, Yue Sun, Hui Cao, Shumei Wang, Jiang Meng. A network pharmacology integrated pharmacokinetics strategy to investigate the pharmacological mechanism of absorbed components from crude and processed Zingiberis Rhizoma on deficiency-cold and hemorrhagic syndrome. Journal of ethnopharmacology. 2023 Jan; 301(?):115754. doi: 10.1016/j.jep.2022.115754. [PMID: 36195301]
  • Nan Li, Xiaojuan Li, Lijuan Deng, Haixin Yang, Zhaohui Gong, Qiang Wang, Dongmei Pan, Shan Zeng, Jiaxu Chen. 6-Shogaol inhibits the proliferation, apoptosis, and migration of rheumatoid arthritis fibroblast-like synoviocytes via the PI3K/AKT/NF-κB pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jan; 109(?):154562. doi: 10.1016/j.phymed.2022.154562. [PMID: 36610124]
  • H Li, J Shen, Y Zhang, L Hu, W Luo. 6-Shogaol protects against isoproterenol-induced cardiac injury in rats through attenutating oxidative stress, inflammation, apoptosis and activating nuclear respiratory factor-2/heme oxygenase-1 signaling pathway. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2022 Dec; 73(6):. doi: 10.26402/jpp.2022.6.06. [PMID: 37087565]
  • Wei-Hao Zhang, Han-Yan Luo, Jing Fang, Chen-Liang Zhao, Kam-Chun Chan, Yui-Man Chan, Cai-Xia Dong, Hu-Biao Chen, Zhong-Zhen Zhao, Song-Lin Li, Jun Xu. Impact of Sulfur Fumigation on Ginger: Chemical and Biological Evidence. Journal of agricultural and food chemistry. 2022 Oct; 70(39):12577-12586. doi: 10.1021/acs.jafc.2c05710. [PMID: 36130944]
  • Sara Ishaq, Sohana Siyar, Rabia Basri, Amna Liaqat, Armeen Hameed, Touqeer Ahmed. Neuroprotective effects of Shogaol in metals (Al, As and Pb) and high fat diet induced neuroinflammation and behavior in mice. Current molecular pharmacology. 2022 Sep; ?(?):. doi: 10.2174/1874467215666220928110557. [PMID: 36173059]
  • S I Othman, M N Bin-Jumah, R S Suliman, S S Althobaiti, E A Alqhtani, S A Gabr. Gingerol fractions bioactivity against butanone cytotoxicity induced in newborns of mice. European review for medical and pharmacological sciences. 2022 09; 26(18):6512-6522. doi: 10.26355/eurrev_202209_29750. [PMID: 36196700]
  • Shuwei Zhang, Emily DiMango, Yingdong Zhu, Tarnjot K Saroya, Charles W Emala, Shengmin Sang. Pharmacokinetics of Gingerols, Shogaols, and Their Metabolites in Asthma Patients. Journal of agricultural and food chemistry. 2022 Aug; 70(31):9674-9683. doi: 10.1021/acs.jafc.2c03150. [PMID: 35916113]
  • Jian-Li Qiu, Yu-Na Chai, Feng-Yang Duan, Hui-Juan Zhang, Xiao-Yan Han, Ling-Yan Chen, Fei Duan. 6-Shogaol alleviates CCl4-induced liver fibrosis by attenuating inflammatory response in mice through the NF-κB pathway. Acta biochimica Polonica. 2022 Apr; 69(2):363-370. doi: 10.18388/abp.2020_5802. [PMID: 35485077]
  • Wenya Jiao, Si Mi, Yaxin Sang, Qiuxia Jin, Bimal Chitrakar, Xianghong Wang, Shuo Wang. Integrated network pharmacology and cellular assay for the investigation of an anti-obesity effect of 6-shogaol. Food chemistry. 2022 Apr; 374(?):131755. doi: 10.1016/j.foodchem.2021.131755. [PMID: 34883426]
  • Chwan-Li Shen, Rui Wang, Guangchen Ji, Moamen M Elmassry, Masoud Zabet-Moghaddam, Heather Vellers, Abdul N Hamood, Xiaoxia Gong, Parvin Mirzaei, Shengmin Sang, Volker Neugebauer. Dietary supplementation of gingerols- and shogaols-enriched ginger root extract attenuate pain-associated behaviors while modulating gut microbiota and metabolites in rats with spinal nerve ligation. The Journal of nutritional biochemistry. 2022 02; 100(?):108904. doi: 10.1016/j.jnutbio.2021.108904. [PMID: 34748918]
  • Sowsan Hafuth, Sukhpal Randhawa. Investigating the Anti-Cancer Properties of 6-Shogaol in Zingiber officinale. Critical reviews in oncogenesis. 2022; 27(3):15-22. doi: 10.1615/critrevoncog.2022045100. [PMID: 37183935]
  • Naiana da Rosa, Fabiana Durante de Medeiros, Juliana de Oliveira, Ana Olívia Martins Laurentino, Eduardo de Medeiros Peretti, Richard Simon Machado, Millena Pais Lourenço, Thatiany Igreja da Silva, Tamires da Cunha Fernandes, Patrícia Alves Reis, Hugo Caire de Castro Faria Neto, Josiane Somariva Prophiro, Jucélia Jeremias Fortunato, Fabrícia Petronilho. 6-Shogaol Exerts a Neuroprotective Factor in Offspring after Maternal Immune Activation in Rats. Developmental neuroscience. 2022; 44(1):13-22. doi: 10.1159/000519992. [PMID: 34695825]
  • Nazanin Momeni Roudsari, Naser-Aldin Lashgari, Saeideh Momtaz, Basil Roufogalis, Amir Hossein Abdolghaffari, Amirhossein Sahebkar. Ginger: A complementary approach for management of cardiovascular diseases. BioFactors (Oxford, England). 2021 Nov; 47(6):933-951. doi: 10.1002/biof.1777. [PMID: 34388275]
  • Mi-Gyeong Gwon, Hyemin Gu, Jaechan Leem, Kwan-Kyu Park. Protective Effects of 6-Shogaol, an Active Compound of Ginger, in a Murine Model of Cisplatin-Induced Acute Kidney Injury. Molecules (Basel, Switzerland). 2021 Sep; 26(19):. doi: 10.3390/molecules26195931. [PMID: 34641472]
  • Giovanni Schepici, Valentina Contestabile, Andrea Valeri, Emanuela Mazzon. Ginger, a Possible Candidate for the Treatment of Dementias?. Molecules (Basel, Switzerland). 2021 Sep; 26(18):. doi: 10.3390/molecules26185700. [PMID: 34577171]
  • Kapil Rai, Narayansing Chhanwal, Nirali N Shah, Rekha S Singhal. Encapsulation of ginger oleoresin in co-crystallized sucrose: development, characterization and storage stability. Food & function. 2021 Sep; 12(17):7964-7974. doi: 10.1039/d1fo00565k. [PMID: 34254624]
  • Niramon Utama-Ang, Sirinapa Sida, Phenphichar Wanachantararak, Arthitaya Kawee-Ai. Development of edible Thai rice film fortified with ginger extract using microwave-assisted extraction for oral antimicrobial properties. Scientific reports. 2021 07; 11(1):14870. doi: 10.1038/s41598-021-94430-y. [PMID: 34290338]
  • Mai T Abdo, Sherweit H El-Ahmady, Haidy A Gad. Quality control and long-term stability study of ginger from different geographical origins using chemometrics. Journal of the science of food and agriculture. 2021 Jun; 101(8):3429-3438. doi: 10.1002/jsfa.10973. [PMID: 33289094]
  • Man-Qian Li, Xue-Yu Hu, Yan-Zhi Wang, Xiao-Juan Zhang, Jian-Peng Li, Zhi-Min Song, Yu-Fei Liu, Wei-Sheng Feng. Qualitative analysis on chemical constituents from different polarity extracted fractions of the pulp and peel of ginger rhizomes by ultra-high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. 2021 Apr; 35(8):e9029. doi: 10.1002/rcm.9029. [PMID: 33326132]
  • H-R Kim, Y-B Eom. Antifungal and anti-biofilm effects of 6-shogaol against Candida auris. Journal of applied microbiology. 2021 Apr; 130(4):1142-1153. doi: 10.1111/jam.14870. [PMID: 32981148]
  • Soo Liang Ooi, Ron Campbell, Sok Cheon Pak, Terry Golombick, Arumugam Manoharan, Raj Ramakrishna, Vladimir Badmaev, Janet Schloss. Is 6-Shogaol an Effective Phytochemical for Patients With Lower-risk Myelodysplastic Syndrome? A Narrative Review. Integrative cancer therapies. 2021 Jan; 20(?):15347354211065038. doi: 10.1177/15347354211065038. [PMID: 34930049]
  • Jing Wang, Yong Chen, Xiaosong Hu, Fengqin Feng, Luyun Cai, Fang Chen. Assessing the Effects of Ginger Extract on Polyphenol Profiles and the Subsequent Impact on the Fecal Microbiota by Simulating Digestion and Fermentation In Vitro. Nutrients. 2020 Oct; 12(10):. doi: 10.3390/nu12103194. [PMID: 33086593]
  • Chunhua Yang, Mingzhen Zhang, Sudeep Lama, Lixin Wang, Didier Merlin. Natural-lipid nanoparticle-based therapeutic approach to deliver 6-shogaol and its metabolites M2 and M13 to the colon to treat ulcerative colitis. Journal of controlled release : official journal of the Controlled Release Society. 2020 07; 323(?):293-310. doi: 10.1016/j.jconrel.2020.04.032. [PMID: 32335157]
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