MG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0) (BioDeep_00000009624)
Main id: BioDeep_00000631444
human metabolite Endogenous blood metabolite
代谢物信息卡片
化学式: C23H38O4 (378.277)
中文名称:
谱图信息:
最多检出来源 Danio rerio(blood) 17.7%
分子结构信息
SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)OCC(O)CO
InChI: InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
描述信息
MG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0) is a monoacylglyceride. A monoglyceride, more correctly known as a monoacylglycerol, is a glyceride consisting of one fatty acid chain covalently bonded to a glycerol molecule through an ester linkage. Monoacylglycerol can be broadly divided into two groups; 1-monoacylglycerols (or 3-monoacylglycerols) and 2-monoacylglycerols, depending on the position of the ester bond on the glycerol moiety. Normally the 1-/3-isomers are not distinguished from each other and are termed alpha-monoacylglycerols, while the 2-isomers are beta-monoacylglycerols. Monoacylglycerols are formed biochemically via release of a fatty acid from diacylglycerol by diacylglycerol lipase or hormone sensitive lipase. Monoacylglycerols are broken down by monoacylglycerol lipase. They tend to be minor components only of most plant and animal tissues, and indeed would not be expected to accumulate because their strong detergent properties would have a disruptive effect on membranes. 2-Monoacylglycerols are a major end product of the intestinal digestion of dietary fats in animals via the enzyme pancreatic lipase. They are taken up directly by the intestinal cells and converted to triacylglycerols via the monoacylglycerol pathway before being transported in lymph to the liver. Mono- and Diglycerides are commonly added to commercial food products in small quantities. They act as emulsifiers, helping to mix ingredients such as oil and water that would not otherwise blend well.
同义名列表
40 个代谢物同义名
(2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate; 2,3-Dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate; 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 1-glyceryl ester; 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-rac-glycerol; 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol; MAG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0); MG(20:4(5Z,8Z,11Z,14Z)/0:0/0:0); (S)-Glyceryl 1-arachidonic acid; (S)-Glyceryl 1-arachidonate; 1-AG;1-arachidonoylglycerol; 1-arachidonoyl-sn-glycerol; MAG(20:4(5Z,8Z,11Z,14Z)); 1-Arachidonoyl Glycerol; 1-arachidonoyl-glycerol; MG(20:4(5Z,8Z,11Z,14Z)); 1-Arachidonoylglycerol; alpha-Monoacylglycerol; 1-Arachidonylglycerol; MAG(20:4W6/0:0/0:0); 1-Monoacylglyceride; MAG(20:4n6/0:0/0:0); a-Monoacylglycerol; MG(20:4n6/0:0/0:0); MG(20:4W6/0:0/0:0); 1-Monoacylglycerol; 1-Monoarachidin; MAG(20:4w6/0:0); MAG(20:4n6/0:0); MG(20:4w6/0:0); MG(20:4n6/0:0); MAG(20:4/0:0); MG(20:4/0:0); MAG(20:4W6); MAG(20:4n6); MG(20:4W6); MG(20:4n6); MAG(20:4); MG(20:4); MG 20:4; 1-AG
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:34071
- ChEBI: CHEBI:75612
- KEGG: C13857
- PubChem: 16019980
- PubChem: 114672
- HMDB: HMDB0011578
- Metlin: METLIN62360
- LipidMAPS: LMGL01010032
- chemspider: 13148726
- CAS: 124511-15-5
- PMhub: MS000023426
- PubChem: 854102
- 3DMET: B05653
- NIKKAJI: J2.646.602D
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Flaminia Fanelli, Valentina D Di Lallo, Ilaria Belluomo, Rosaria De Iasio, Margherita Baccini, Elena Casadio, Daniela Ibarra Gasparini, Michelangelo Colavita, Alessandra Gambineri, Gabriele Grossi, Valentina Vicennati, Renato Pasquali, Uberto Pagotto. Estimation of reference intervals of five endocannabinoids and endocannabinoid related compounds in human plasma by two dimensional-LC/MS/MS.
Journal of lipid research.
2012 Mar; 53(3):481-493. doi:
10.1194/jlr.m021378. [PMID: 22172516] - Alexander A Zoerner, Christin Rakers, Stefan Engeli, Sandor Batkai, Marcus May, Jens Jordan, Dimitrios Tsikas. Peripheral endocannabinoid microdialysis: in vitro characterization and proof-of-concept in human subjects.
Analytical and bioanalytical chemistry.
2012 Mar; 402(9):2727-35. doi:
10.1007/s00216-012-5729-9. [PMID: 22311425] - Alexander A Zoerner, Sandor Batkai, Maria-Theresia Suchy, Frank-Mathias Gutzki, Stefan Engeli, Jens Jordan, Dimitrios Tsikas. Simultaneous UPLC-MS/MS quantification of the endocannabinoids 2-arachidonoyl glycerol (2AG), 1-arachidonoyl glycerol (1AG), and anandamide in human plasma: minimization of matrix-effects, 2AG/1AG isomerization and degradation by toluene solvent extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Feb; 883-884(?):161-71. doi:
10.1016/j.jchromb.2011.06.025. [PMID: 21752730] - Alexander A Zoerner, Frank-Mathias Gutzki, Sandor Batkai, Marcus May, Christin Rakers, Stefan Engeli, Jens Jordan, Dimitrios Tsikas. Quantification of endocannabinoids in biological systems by chromatography and mass spectrometry: a comprehensive review from an analytical and biological perspective.
Biochimica et biophysica acta.
2011 Nov; 1811(11):706-23. doi:
10.1016/j.bbalip.2011.08.004. [PMID: 21875688] - Gabor Tigyi. Aiming drug discovery at lysophosphatidic acid targets.
British journal of pharmacology.
2010 Sep; 161(2):241-70. doi:
10.1111/j.1476-5381.2010.00815.x. [PMID: 20735414] - Yin Duan, Jian Zheng, Russell A Nicholson. Inhibition of [3H]batrachotoxinin A-20alpha-benzoate binding to sodium channels and sodium channel function by endocannabinoids.
Neurochemistry international.
2008 Feb; 52(3):438-46. doi:
10.1016/j.neuint.2007.08.004. [PMID: 17888543]
