Ethynodiol Diacetate (BioDeep_00000009378)
Main id: BioDeep_00000009419
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
[(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
化学式: C24H32O4 (384.23)
中文名称: 双醋炔诺醇
谱图信息:
最多检出来源 Homo sapiens(blood) 62.1%
分子结构信息
SMILES: C#CC1(OC(C)=O)CCC2C3CCC4=CC(OC(C)=O)CCC4C3CCC21C
InChI: InChI=1S/C24H32O4/c1-5-24(28-16(3)26)13-11-22-21-8-6-17-14-18(27-15(2)25)7-9-19(17)20(21)10-12-23(22,24)4/h1,14,18-22H,6-13H2,2-4H3/t18-,19-,20+,21+,22-,23-,24-/m0/s1
描述信息
Ethynodiol Diacetate is only found in individuals that have used or taken this drug. It is a synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. [PubChem]Binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Ethynodiol Diacetate will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D012102 - Reproductive Control Agents > D003270 - Contraceptive Agents
Same as: D01294
同义名列表
53 个代谢物同义名
[(3S,8R,9S,10R,13S,14S,17R)-17-acetyloxy-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate; (1S,2R,5S,10R,11S,14R,15S)-5-(acetyloxy)-14-ethynyl-15-methyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl acetate; 17alpha-Ethynyl-19-norandrost-4-ene-3beta,17-beta-diol diacetic acid; 17alpha-Ethynyl-19-norandrost-4-ene-3beta,17-beta-diol diacetate; (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol diacetate; 19-Nor-17alpha-pregn-4-en-20-yne-3beta,17-diol diacetic acid; 17Α-ethynyl-19-norandrost-4-ene-3β,17-β-diol diacetic acid; 17a-Ethynyl-19-norandrost-4-ene-3b,17-b-diol diacetic acid; 17alpha-Ethynyl-4-estrene-3beta,17beta-diol diacetic acid; 19-Nor-17alpha-pregn-4-en-20-yne-3beta,17-diol diacetate; 3beta,17beta-Diacetoxy-19-nor-17alpha-pregn-4-en-20-yne; 17alpha-Ethynylestr-4-ene-3beta,17beta-diol acetic acid; 17alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetic acid; 17a-Ethynyl-19-norandrost-4-ene-3b,17-b-diol diacetate; 17Α-ethynyl-19-norandrost-4-ene-3β,17-β-diol diacetate; 19-Nor-17α-pregn-4-en-20-yne-3β,17-diol diacetic acid; 19-Nor-17a-pregn-4-en-20-yne-3b,17-diol diacetic acid; 17alpha-Ethynyl-4-estrene-3beta,17beta-diol diacetate; 19-norpregn-4-en-20-yn-3beta,17alpha-diol, diacetate; 17alpha-Ethynylestr-4-ene-3beta,17beta-diol acetate; 17Α-ethynyl-3,17-dihydroxy-4-estrene diacetic acid; 3beta, 17beta-Diacetoxy-17alpha-ethynyl-4-oestrene; 17alpha-Ethynyl-3,17-dihydroxy-4-estrene diacetate; 17a-Ethynyl-3,17-dihydroxy-4-estrene diacetic acid; 19-Nor-17a-pregn-4-en-20-yne-3b,17-diol diacetate; 19-Nor-17α-pregn-4-en-20-yne-3β,17-diol diacetate; 17a-Ethynyl-4-estrene-3b,17b-diol diacetic acid; 17Α-ethynyl-4-estrene-3β,17β-diol diacetic acid; 17a-Ethynyl-3,17-dihydroxy-4-estrene diacetate; 17Α-ethynyl-3,17-dihydroxy-4-estrene diacetate; 3Β,17β-diacetoxy-19-nor-17α-pregn-4-en-20-yne; 17Α-ethynylestr-4-ene-3β,17β-diol acetic acid; 3b,17b-Diacetoxy-19-nor-17a-pregn-4-en-20-yne; 17a-Ethynylestr-4-ene-3b,17b-diol acetic acid; 17Α-ethynyl-4-estrene-3β,17β-diol diacetate; 17a-Ethynyl-4-estrene-3b,17b-diol diacetate; 17Α-ethynylestr-4-ene-3β,17β-diol acetate; 17a-Ethynylestr-4-ene-3b,17b-diol acetate; 3Β, 17β-diacetoxy-17α-ethynyl-4-oestrene; 3b, 17b-Diacetoxy-17a-ethynyl-4-oestrene; Ethynodiol diacetate, (17 alpha)-isomer; Ethynodiol diacetic acid; Diacetate, ethynodiol; Diacetate, ethyndiol; Ethinodiol diacetate; Ethynodiol Diacetate; Ethyndiol diacetate; Ethynodiol; ST 24:5;O4; Continuin; etynodiol; Femulen; Ethynodiol diacetate
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:31580
- KEGG: C12724
- PubChem: 9270
- HMDB: HMDB0014961
- Metlin: METLIN2606
- DrugBank: DB00823
- ChEMBL: CHEMBL1200624
- Wikipedia: Ethynodiol_Diacetate
- LipidMAPS: LMST02030124
- MeSH: Ethynodiol Diacetate
- chemspider: 8913
- CAS: 297-76-7
- PMhub: MS000023157
- PubChem: 583113
- 3DMET: B04554
- NIKKAJI: J5.459C
- KNApSAcK: 31580
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
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Journal of pharmaceutical sciences.
1975 Nov; 64(11):1776-81. doi:
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Steroids.
1975 Jun; 25(6):829-47. doi:
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The American journal of clinical nutrition.
1975 Jun; 28(6):606-15. doi:
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Circulation.
1975 May; 51(5):916-23. doi:
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The American journal of clinical nutrition.
1975 Apr; 28(4):354-62. doi:
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Diabetologia.
1975 Feb; 11(1):45-8. doi:
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International journal of fertility.
1975; 20(1):27-9. doi:
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Fertility and sterility.
1975 Jan; 26(1):62-7. doi:
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The Journal of clinical endocrinology and metabolism.
1974 Dec; 39(6):1001-4. doi:
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Fertility and sterility.
1974 Nov; 25(11):927-34. doi:
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The Journal of obstetrics and gynaecology of the British Commonwealth.
1974 Oct; 81(10):804-11. doi:
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The American journal of clinical nutrition.
1974 Aug; 27(8):797-805. doi:
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American journal of obstetrics and gynecology.
1974 May; 119(2):266-7. doi:
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Nutrition reviews.
1974 May; 32(5):149-52. doi:
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Clinical obstetrics and gynecology.
1974 Mar; 17(1):35-51. doi:
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Obstetrics and gynecology.
1974 Jan; 43(1):87-96. doi:
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Urology.
1973 Dec; 2(6):683-5. doi:
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Metabolism: clinical and experimental.
1973 Dec; 22(12):1499-505. doi:
10.1016/0026-0495(73)90018-8. [PMID: 4587003] - W A Walters, D Cain. Haemodynamic effects of low doses of female sex steroids.
The Australian & New Zealand journal of obstetrics & gynaecology.
1973 Nov; 13(4):213-8. doi:
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Analytical biochemistry.
1973 Nov; 56(1):178-90. doi:
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The Journal of nutrition.
1973 Sep; 103(9):1270-8. doi:
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The Journal of clinical endocrinology and metabolism.
1973 Aug; 37(2):254-60. doi:
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The Journal of pharmacology and experimental therapeutics.
1973 Jun; 185(3):696-702. doi:
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Journal of obstetrics and gynaecology of India.
1973 Apr; 23(2):148-51. doi:
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Geburtshilfe und Frauenheilkunde.
1973 Apr; 33(4):310-4. doi:
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Fertility and sterility.
1973 Mar; 24(3):178-84. doi:
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Metabolism: clinical and experimental.
1973 Feb; 22(2):165-71. doi:
10.1016/0026-0495(73)90267-9. [PMID: 4683526] - P I Singh, U Kapoor, V R Bajaj. Plasma amino acids in subjects taking oral contraceptives.
Journal of obstetrics and gynaecology of India.
1973 Feb; 23(1):33-7. doi:
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The Journal of obstetrics and gynaecology of the British Commonwealth.
1973 Jan; 80(1):82-5. doi:
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American journal of obstetrics and gynecology.
1972 Oct; 114(4):484-91. doi:
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Acta Europaea fertilitatis.
1972 Sep; 3(3):269-80. doi:
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The American journal of clinical nutrition.
1972 Jul; 25(7):684-9. doi:
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The Journal of endocrinology.
1972 Jul; 54(1):47-53. doi:
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American journal of obstetrics and gynecology.
1972 Jun; 113(3):420-32. doi:
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Acta Europaea fertilitatis.
1972 Jun; 3(2):141-6. doi:
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The Journal of clinical endocrinology and metabolism.
1972 May; 34(5):819-21. doi:
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