o-Phenylenediamine (BioDeep_00000004322)
Secondary id: BioDeep_00001871788
human metabolite blood metabolite
代谢物信息卡片
1,2-Diaminobenzene dihydrochloride
化学式: C6H8N2 (108.0687)
中文名称: 邻苯二胺(OPD), 邻苯二胺
谱图信息:
最多检出来源 Homo sapiens(blood) 4.51%
分子结构信息
SMILES: C1=CC=C(C(=C1)N)N
InChI: InChI=1S/C6H8N2/c7-5-3-1-2-4-6(5)8/h1-4H,7-8H2
描述信息
同义名列表
14 个代谢物同义名
1,2-Diaminobenzene dihydrochloride; Ortho-phenylenediamine; Orthophenylenediamine; Phenylene-1,2-dimaine; 1,2-Phenylenediamine; benzene-1,2-diamine; 2-Phenylene diamine; O-PHENYLENEDIAMINE; 1,2-Diaminobenzene; 2,3-Diaminobenzene; 2-Aminoaniline; OPDA; 1,2-Diaminobenzene; o-Phenylenediamine
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:34043
- KEGG: C14402
- PubChem: 7243
- HMDB: HMDB0255864
- Metlin: METLIN70033
- ChEMBL: CHEMBL70582
- Wikipedia: O-Phenylenediamine
- chemspider: 13837582
- CAS: 95-54-5
- PMhub: MS000016545
- PubChem: 17395402
- NIKKAJI: J3.954C
- KNApSAcK: 34043
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yunxiao Feng, Gang Liu, Chunhuan Zhang, Jinrui Li, Yuanyuan Li, Lin Liu. Fluorescent Immunoassay with a Copper Polymer as the Signal Label for Catalytic Oxidation of O-Phenylenediamine.
Molecules (Basel, Switzerland).
2022 Jun; 27(12):. doi:
10.3390/molecules27123675. [PMID: 35744801] - Minyu Zha, Li Lian, Mingchun Wen, Sezai Ercisli, Yiyu Ren, Zongde Jiang, Chi-Tang Ho, Liang Zhang. The Oxidation Mechanism of Flavan-3-ols by an Enzymatic Reaction Using Liquid Chromatography-Mass Spectrometry-Based Metabolomics Combined with Captured o-Quinone Intermediates of Flavan-3-ols by o-Phenylenediamine.
Journal of agricultural and food chemistry.
2022 May; 70(18):5715-5727. doi:
10.1021/acs.jafc.2c01416. [PMID: 35475606] - Wei Zhang, Yu Zhang, Xin Liu, Yue Zhang, Yibing Liu, Wei Wang, Rui Su, Ying Sun, Yibing Huang, Daqian Song, Yanhua Wu, Xinghua Wang. Ratiometric fluorescence and colorimetric dual-mode sensing platform based on carbon dots for detecting copper(II) ions and D-penicillamine.
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2022 Feb; 414(4):1651-1662. doi:
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10.1186/1479-5876-9-21. [PMID: 21345239] - Jan Hrbacek, Michael Urban, Eva Hamsikova, Ruth Tachezy, Vaclav Eis, Marek Brabec, Jiri Heracek. Serum antibodies against genitourinary infectious agents in prostate cancer and benign prostate hyperplasia patients: a case-control study.
BMC cancer.
2011 Feb; 11(?):53. doi:
10.1186/1471-2407-11-53. [PMID: 21291519] - Eusebio S Pires, Asmita K Choudhury, Susan Idicula-Thomas, Vrinda V Khole. Anti-HSP90 autoantibodies in sera of infertile women identify a dominant, conserved epitope EP6 (380-389) of HSP90 beta protein.
Reproductive biology and endocrinology : RB&E.
2011 Jan; 9(?):16. doi:
10.1186/1477-7827-9-16. [PMID: 21272367] - Karina A Pasquevich, Andrés E Ibañez, Lorena M Coria, Clara García Samartino, Silvia M Estein, Astrid Zwerdling, Paula Barrionuevo, Fernanda S Oliveira, Christine Seither, Heribert Warzecha, Sergio C Oliveira, Guillermo H Giambartolomei, Juliana Cassataro. An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.
PloS one.
2011 Jan; 6(1):e16203. doi:
10.1371/journal.pone.0016203. [PMID: 21264260] - Mouhssin Oufir, Leslie R Bisset, Stefan R K Hoffmann, Gongda Xue, Stephan Klauser, Bianca Bergamaschi, Alain Gervaix, Jürg Böni, Jörg Schüpbach, Bernd Gutte. Artificial 64-Residue HIV-1 Enhancer-Binding Peptide Is a Potent Inhibitor of Viral Replication in HIV-1-Infected Cells.
Advances in virology.
2011; 2011(?):165871. doi:
10.1155/2011/165871. [PMID: 22312334] - Ana Jolly, Silvia Beatriz Colavecchia, Bárbara Fernández, Eloy Fernández, Silvia Leonor Mundo. Antibodies Induced by Lipoarabinomannan in Bovines: Characterization and Effects on the Interaction between Mycobacterium Avium Subsp. Paratuberculosis and Macrophages In Vitro.
Veterinary medicine international.
2011; 2011(?):258479. doi:
10.4061/2011/258479. [PMID: 21772964] - Yingwei Zhang, Hailong Li, Yonglan Luo, Xu Shi, Jingqi Tian, Xuping Sun. Poly(m-phenylenediamine) nanospheres and nanorods: selective synthesis and their application for multiplex nucleic acid detection.
PloS one.
2011; 6(6):e20569. doi:
10.1371/journal.pone.0020569. [PMID: 21731617] - Ju-Hee Lee, Gi-Hyun Kim, Sang Min Kim, Sang Yeub Lee, Won-Yik Lee, Jang-Whan Bae, Kyung-Sub Shin, Kyung-Kuk Hwang, Dong-Won Kim, Myeong-Chan Cho. A case of sparganosis that presented as a recurrent pericardial effusion.
Korean circulation journal.
2011 Jan; 41(1):38-42. doi:
10.4070/kcj.2011.41.1.38. [PMID: 21359068] - Yong Chang Seo, Woon Yong Choi, Choon Geun Lee, Seon Woo Cha, Young Ock Kim, Jin-Chul Kim, Gregor P C Drummen, Hyeon Yong Lee. Enhanced immunomodulatory activity of gelatin-encapsulated Rubus coreanus Miquel nanoparticles.
International journal of molecular sciences.
2011; 12(12):9031-56. doi:
10.3390/ijms12129031. [PMID: 22272118] - Teresa R McCurdy, Varsha Bhakta, Louise J Eltringham-Smith, Sharon Gataiance, Alison E Fox-Robichaud, William P Sheffield. Comparison of methods for the purification of alpha-1 acid glycoprotein from human plasma.
Journal of biomedicine & biotechnology.
2011; 2011(?):578207. doi:
10.1155/2011/578207. [PMID: 21437215] - Subhankari Prasad Chakraborty, Santanu Kar Mahapatra, Sumanta Kumar Sahu, Sabyasachi Das, Satyajit Tripathy, Sandeep Dash, Panchanan Pramanik, Somenath Roy. Internalization of Staphylococcus aureus in lymphocytes induces oxidative stress and DNA fragmentation: possible ameliorative role of nanoconjugated vancomycin.
Oxidative medicine and cellular longevity.
2011; 2011(?):942123. doi:
10.1155/2011/942123. [PMID: 21941607] - Subhankari Prasad Chakraborty, Santanu Karmahapatra, Sumanta Kumar Sahu, Panchanan Pramanik, Somenath Roy. Amelioratory Effect of Nanoconjugated Vancomycin on Spleen during VRSA-Induced Oxidative Stress.
Pathology research international.
2011; 2011(?):420198. doi:
10.4061/2011/420198. [PMID: 21785683] - Ao-Ho Hsieh, Yí-Jyun Jhou, Chung-Ting Liang, Mingi Chang, Shih-Lien Wang. Fragment of tegument protein pp65 of human cytomegalovirus induces autoantibodies in BALB/c mice.
Arthritis research & therapy.
2011; 13(5):R162. doi:
10.1186/ar3481. [PMID: 21989080] - Renato Lopes de Souza, João Tomás Abreu Carvalhaes, Lucilia Sanae Nishimura, Maria Cristina de Andrade, Beatriz Ernestina Cabilio Guth. Hemolytic uremic syndrome in pediatric intensive care units in são paulo, Brazil.
The open microbiology journal.
2011; 5(?):76-82. doi:
10.2174/1874285801105010076. [PMID: 21804902] - Hossain Ali Mondal, Dipankar Chakraborti, Pralay Majumder, Pampa Roy, Amit Roy, Swati Gupta Bhattacharya, Sampa Das. Allergenicity assessment of Allium sativum leaf agglutinin, a potential candidate protein for developing sap sucking insect resistant food crops.
PloS one.
2011; 6(11):e27716. doi:
10.1371/journal.pone.0027716. [PMID: 22110739] - Lubica Grausova, Alexander Kromka, Zuzana Burdikova, Adam Eckhardt, Bohuslav Rezek, Jiri Vacik, Ken Haenen, Vera Lisa, Lucie Bacakova. Enhanced growth and osteogenic differentiation of human osteoblast-like cells on boron-doped nanocrystalline diamond thin films.
PloS one.
2011; 6(6):e20943. doi:
10.1371/journal.pone.0020943. [PMID: 21695172] - David Duguay, Erika Bélanger-Nelson, Valérie Mongrain, Anna Beben, Armen Khatchadourian, Nicolas Cermakian. Dynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptor.
PloS one.
2011; 6(10):e26430. doi:
10.1371/journal.pone.0026430. [PMID: 22028875] - Petronela Zižková, Jana Viskupičová, L'ubica Horáková. Pycnogenol and Ginkgo biloba extract: effect on peroxynitrite-oxidized sarcoplasmic reticulum Ca-ATPase.
Interdisciplinary toxicology.
2010 Dec; 3(4):132-6. doi:
10.2478/v10102-010-0053-8. [PMID: 21331179] - Luise H Brand, Tobias Kirchler, Sabine Hummel, Christina Chaban, Dierk Wanke. DPI-ELISA: a fast and versatile method to specify the binding of plant transcription factors to DNA in vitro.
Plant methods.
2010 Nov; 6(?):25. doi:
10.1186/1746-4811-6-25. [PMID: 21108821] - Yi-ling Lu, Ben-xia Yang, Zong-ning Yin. Immunotargeting of collagenase on thrombus.
International journal of nanomedicine.
2010 Nov; 5(?):973-82. doi:
10.2147/ijn.s13904. [PMID: 21187949] - Peng-Cheng Xu, Min Chen, Zhao Cui, Ming-Hui Zhao. Influence of myeloperoxidase by anti-myeloperoxidase antibodies and its association with the disease activity in microscopic polyangiitis.
Rheumatology (Oxford, England).
2010 Nov; 49(11):2068-75. doi:
10.1093/rheumatology/keq203. [PMID: 20675709] - Corinna Siegel, Teresia Hallström, Christine Skerka, Hannes Eberhardt, Barbara Uzonyi, Tobias Beckhaus, Michael Karas, Reinhard Wallich, Brian Stevenson, Peter F Zipfel, Peter Kraiczy. Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi.
PloS one.
2010 Oct; 5(10):e13519. doi:
10.1371/journal.pone.0013519. [PMID: 20975954] - Osama A Hamad, Per H Nilsson, Maria Lasaosa, Daniel Ricklin, John D Lambris, Bo Nilsson, Kristina Nilsson Ekdahl. Contribution of chondroitin sulfate A to the binding of complement proteins to activated platelets.
PloS one.
2010 Sep; 5(9):e12889. doi:
10.1371/journal.pone.0012889. [PMID: 20886107] - J Abdi, B Kazemi, A Haniloo, M Mohebali, M Mahmoudi, S Rezaei, M Bandehpour, L Maghen, Mb Rokni. Serological Evaluation of EgAgB16 kDa, a Recombinant Antigen from Echinococcus granulosus for Diagnosis of Human Hydatidosis.
Iranian journal of parasitology.
2010 Sep; 5(3):1-10. doi:
NULL. [PMID: 22347249] - Sujoy Das, Sudipta Saha, Gopal Chandra Majumder, Sandhya Rekha Dungdung. Purification and characterization of a sperm motility inhibiting factor from caprine epididymal plasma.
PloS one.
2010 Aug; 5(8):e12039. doi:
10.1371/journal.pone.0012039. [PMID: 20706623] - Melina Laguía-Becher, Valentina Martín, Mauricio Kraemer, Mariana Corigliano, María L Yacono, Alejandra Goldman, Marina Clemente. Effect of codon optimization and subcellular targeting on Toxoplasma gondii antigen SAG1 expression in tobacco leaves to use in subcutaneous and oral immunization in mice.
BMC biotechnology.
2010 Jul; 10(?):52. doi:
10.1186/1472-6750-10-52. [PMID: 20633272] - Anja Smykowski, Petra Zimmermann, Ulrike Zentgraf. G-Box binding factor1 reduces CATALASE2 expression and regulates the onset of leaf senescence in Arabidopsis.
Plant physiology.
2010 Jul; 153(3):1321-31. doi:
10.1104/pp.110.157180. [PMID: 20484024] - William M Switzer, Hongwei Jia, Oliver Hohn, HaoQiang Zheng, Shaohua Tang, Anupama Shankar, Norbert Bannert, Graham Simmons, R Michael Hendry, Virginia R Falkenberg, William C Reeves, Walid Heneine. Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States.
Retrovirology.
2010 Jul; 7(?):57. doi:
10.1186/1742-4690-7-57. [PMID: 20594299] - Tannaz Birdi, Poonam Daswani, S Brijesh, Pundarikakshudu Tetali, Arvind Natu, Noshir Antia. Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea.
BMC complementary and alternative medicine.
2010 Jun; 10(?):33. doi:
10.1186/1472-6882-10-33. [PMID: 20584265] - Bassam R Ali, Huifang Xu, Nadia A Akawi, Anne John, Noushad S Karuvantevida, Ruth Langer, Lihadh Al-Gazali, Birgit Leitinger. Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients.
Human molecular genetics.
2010 Jun; 19(11):2239-50. doi:
10.1093/hmg/ddq103. [PMID: 20223752] - Yueming Tan, Wenfang Deng, Yunyong Li, Zhao Huang, Yue Meng, Qingji Xie, Ming Ma, Shouzhuo Yao. Polymeric bionanocomposite cast thin films with in situ laccase-catalyzed polymerization of dopamine for biosensing and biofuel cell applications.
The journal of physical chemistry. B.
2010 Apr; 114(15):5016-24. doi:
10.1021/jp100922t. [PMID: 20337455] - Philippe Colson, Hervé Richet, Christelle Desnues, Fanny Balique, Valérie Moal, Jean-Jacques Grob, Philippe Berbis, Hervé Lecoq, Jean-Robert Harlé, Yvon Berland, Didier Raoult. Pepper mild mottle virus, a plant virus associated with specific immune responses, Fever, abdominal pains, and pruritus in humans.
PloS one.
2010 Apr; 5(4):e10041. doi:
10.1371/journal.pone.0010041. [PMID: 20386604] - Qiao Xu, Fang Wei, Zhan Wang, Qin Yang, Yuan-Di Zhao, Hong Chen. In vivo monitor oxidative burst induced by Cd2+ stress for the oilseed rape (Brassica napus L.) based on electrochemical microbiosensor.
Phytochemical analysis : PCA.
2010 Mar; 21(2):192-6. doi:
10.1002/pca.1178. [PMID: 19908213] - Carmen Calinescu, Rodolfo Federico, Bruno Mondovi, Mircea Alexandru Mateescu. Zymographic assay of plant diamine oxidase on entrapped peroxidase polyacrylamide gel electrophoresis. A study of stability to proteolysis.
Analytical and bioanalytical chemistry.
2010 Feb; 396(3):1281-90. doi:
10.1007/s00216-009-3306-7. [PMID: 20091155] - Gavin Y Oudit, George C Liu, Jiuchang Zhong, Ratnadeep Basu, Fung L Chow, Joyce Zhou, Hans Loibner, Evelyne Janzek, Manfred Schuster, Josef M Penninger, Andrew M Herzenberg, Zamaneh Kassiri, James W Scholey. Human recombinant ACE2 reduces the progression of diabetic nephropathy.
Diabetes.
2010 Feb; 59(2):529-38. doi:
10.2337/db09-1218. [PMID: 19934006] - Hiroshi Izuta, Nozomu Matsunaga, Masamitsu Shimazawa, Tetsuya Sugiyama, Tsunehiko Ikeda, Hideaki Hara. Proliferative diabetic retinopathy and relations among antioxidant activity, oxidative stress, and VEGF in the vitreous body.
Molecular vision.
2010 Jan; 16(?):130-6. doi:
NULL. [PMID: 20142849] - Caifeng Ding, Hui Li, Kongcheng Hu, Jin-Ming Lin. Electrochemical immunoassay of hepatitis B surface antigen by the amplification of gold nanoparticles based on the nanoporous gold electrode.
Talanta.
2010 Jan; 80(3):1385-91. doi:
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