Trimethylglycine (BioDeep_00000000198)

 

Secondary id: BioDeep_00000266629, BioDeep_00001867472

natural product human metabolite PANOMIX_OTCML-2023 Chemicals and Drugs BioNovoGene_Lab2019


代谢物信息卡片


Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt

化学式: C5H11NO2 (117.079)
中文名称: 甜菜碱 (无水), 甜菜碱,无水, 甜菜碱, 甜菜碱 无水
谱图信息: 最多检出来源 Homo sapiens(plant) 7.54%

分子结构信息

SMILES: C[N+](C)(C)CC(=O)[O-]
InChI: InChI=1/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3

描述信息

Glycine betaine is the amino acid betaine derived from glycine. It has a role as a fundamental metabolite. It is an amino-acid betaine and a glycine derivative. It is a conjugate base of a N,N,N-trimethylglycinium.
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function. Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and urine. Currently, no treatments are available to correct the genetic causes of homocystinuria. However, in order to normalize homocysteine levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and specific diets. Betaine reduces plasma homocysteine levels in patients with homocystinuria. Although it is present in many food products, the levels found there are insufficient to treat this condition. The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment of homocystinuria, and the EMA has approved the use of Amversio (betaine anhydrous, oral powder).
Betaine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).
Betaine is a Methylating Agent. The mechanism of action of betaine is as a Methylating Activity.
Betaine is a modified amino acid consisting of glycine with three methyl groups that serves as a methyl donor in several metabolic pathways and is used to treat the rare genetic causes of homocystinuria. Betaine has had only limited clinical use, but has not been linked to instances of serum enzyme elevations during therapy or to clinically apparent liver injury.
Betaine is a natural product found in Hypoestes phyllostachya, Barleria lupulina, and other organisms with data available.
Betaine is a metabolite found in or produced by Saccharomyces cerevisiae.
A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341)
See also: Arnica montana Flower (part of); Betaine; panthenol (component of); Betaine; scutellaria baicalensis root (component of) ... View More ...
A - Alimentary tract and metabolism > A16 - Other alimentary tract and metabolism products > A16A - Other alimentary tract and metabolism products > A16AA - Amino acids and derivatives
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D008082 - Lipotropic Agents
Acquisition and generation of the data is financially supported in part by CREST/JST.
D009676 - Noxae > D000963 - Antimetabolites
CONFIDENCE standard compound; ML_ID 42
D005765 - Gastrointestinal Agents
KEIO_ID B047

同义名列表

110 个代谢物同义名

Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt; 1-Carboxy-N,N,N-trimethylmethanaminium hydroxide, inner salt; Methanaminium, 1-carboxy-N,N,N-trimethyl-, inner salt (9CI); 2-(Trimethylammonio)ethanoic acid, hydroxide, inner salt; (Carboxymethyl)trimethylammonium hydroxide, inner salt; Methanaminium, 1-carboxy-N,N,N-trimethyl-, inner salt; (Carboxymethyl)trimethylammonium hydroxide inner salt; methanaminium, carboxy-N,N,N-trimethyl-, inner salt; Methanaminium,N,N-trimethyl-, hydroxide, inner salt; 1-Carboxy-N,N,N-trimethylmethanaminium inner salt; 4-04-00-02369 (Beilstein Handbook Reference); Methanaminium, 1-carboxy-N,N,N-trimethyl-; Abromine; Lycine; Trimethylglycine (TMG); Betaine Anhydrous For Oral Solution; Dr.Jucre Rebirth Activating Toner; 2-N,N,N-trimethylammonio acetate; (Carboxymethyl)trimethylammonium; 2-(trimethylamino)acetic acid; N,N,N-trimethylammonioacetate; 2-(trimethylazaniumyl)acetate; BETAINE ANHYDROUS [EMA EPAR]; (trimethylammoniumyl)acetate; trimethylglycocoll anhydride; Citrate de Bétaïne Beaufour; 2-(Trimethylammonio)Acetate; 2-trimethylammonioacetate; Glycine, trimethylbetaine; (Trimethylammonio)acetate; Trimethylaminoacetic acid; Glykokollbetain [German]; Citrate de Bétaïne UPSA; trimethylammonioacetate; WLN: QV1K1 & 1 & 1 & Q; Hydrochloride, Betaine; N,N,N-trimethylglycine; Trimethylaminoacetate; BETAINE [ORANGE BOOK]; Betaine Hydrochloride; BETAINE, ANHYDROUS; Trimethylglycocoll; ATONO2 Oxygen Baby; Glycocoll betaine; Betaine anhydrous; BETAINE [USP-RS]; .alpha.-Earleine; Betaine, Glycine; BETAINE [WHO-DD]; BETAINE (USP-RS); Trimethylglycine; Betaineanhydrous; BETAINE [VANDF]; betaina anhidra; Glykokollbetain; Loramine AMB 13; BETAINE (MART.); BETAINE [MART.]; UNII-3SCV180C9W; glycine betaine; BETAINE [HSDB]; Scorbo-bétaïne; BETAINE [INCI]; GLYCINEBETAINE; BETAINE [FHFI]; Scorbo bétaïne; Cystadane (TN); alpha-Earleine; Glycylbetaine; Betaine (8CI); Scorbobétaïne; acidin-pepsin; BETAINE [JAN]; Betaine (JAN); BETAINE [FCC]; Acidin Pepsin; BETAINE [MI]; Tox21_301159; AcidinPepsin; Tox21_113511; Novobetaine; Betaine,(S); Betafin BCR; oxyneurine; Betafin BP; 3SCV180C9W; Cystadane; Rubrine C; AI3-24187; .beta.ine; Aminocoat; AI3-52598; Greenstim; Hepastyl; FinnStim; Jortaine; Abromine; Betafin; Betaine; Stea 16; Stea-16; C.B.B.; Stea16; lycine; Acidol; 3mam; 3ppp; 3l6h; BET; Betaine; Betaine; Betaine



数据库引用编号

36 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(12)

PlantCyc(0)

代谢反应

501 个相关的代谢反应过程信息。

Reactome(56)

BioCyc(60)

WikiPathways(3)

Plant Reactome(296)

INOH(2)

PlantCyc(23)

COVID-19 Disease Map(0)

PathBank(61)

PharmGKB(0)

187 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 AKT1, CASP3, CBS, GPX1, HMGB1, HPGDS, ITPR3, MTR, PTGS2, SLC9A1, TLR4
Peripheral membrane protein 2 HMGB1, PTGS2
Endosome membrane 1 TLR4
Endoplasmic reticulum membrane 3 ITPR3, PEMT, PTGS2
Mitochondrion membrane 1 PEMT
Nucleus 4 AKT1, CASP3, CBS, HMGB1
cytosol 10 AKT1, CASP3, CBS, GPX1, GSR, HPGDS, LEP, MTHFR, MTR, PEMT
mitochondrial membrane 1 PEMT
nucleoplasm 7 AKT1, ATP2B1, CASP3, HMGB1, HPGDS, ITPR3, SLC9A1
Cell membrane 7 AKT1, ATP2B1, HMGB1, SLC6A12, SLC6A8, SLC9A1, TLR4
lamellipodium 2 AKT1, SLC9A1
Multi-pass membrane protein 6 ATP2B1, ITPR3, PEMT, SLC6A12, SLC6A8, SLC9A1
Synapse 1 ATP2B1
cell cortex 1 AKT1
cell surface 3 HMGB1, SLC9A1, TLR4
glutamatergic synapse 3 AKT1, ATP2B1, CASP3
neuronal cell body 2 CASP3, ITPR3
postsynapse 1 AKT1
presynaptic membrane 1 ATP2B1
Presynapse 1 SLC6A12
endosome 1 HMGB1
plasma membrane 8 AKT1, ATP2B1, HMGB1, ITPR3, SLC6A12, SLC6A8, SLC9A1, TLR4
synaptic vesicle membrane 1 ATP2B1
Membrane 8 AKT1, ATP2B1, ITPR3, PEMT, SLC6A12, SLC6A8, SLC9A1, TLR4
apical plasma membrane 2 SLC6A8, SLC9A1
basolateral plasma membrane 3 ATP2B1, SLC6A12, SLC9A1
brush border 1 ITPR3
caveola 1 PTGS2
extracellular exosome 4 ATP2B1, GSR, LYZ, SLC9A1
endoplasmic reticulum 4 HMGB1, ITPR3, PEMT, PTGS2
extracellular space 4 CRP, HMGB1, LEP, LYZ
perinuclear region of cytoplasm 2 SLC9A1, TLR4
intercalated disc 1 SLC9A1
mitochondrion 4 GPX1, GSR, PEMT, SLC9A1
protein-containing complex 2 AKT1, PTGS2
intracellular membrane-bounded organelle 3 ATP2B1, HPGDS, PEMT
Microsome membrane 1 PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 TLR4
Secreted 3 CRP, HMGB1, LEP
extracellular region 4 CRP, HMGB1, LEP, LYZ
mitochondrial matrix 2 GPX1, GSR
Extracellular side 1 HMGB1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 2 GSR, TLR4
T-tubule 1 SLC9A1
microtubule cytoskeleton 1 AKT1
nucleolus 1 ITPR3
Early endosome 1 TLR4
apical part of cell 1 ITPR3
cell-cell junction 1 AKT1
vesicle 1 AKT1
Apical cell membrane 1 SLC6A8
Membrane raft 1 SLC9A1
focal adhesion 1 SLC9A1
spindle 1 AKT1
sarcoplasmic reticulum 1 ITPR3
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
lateral plasma membrane 1 ATP2B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 2 ITPR3, PTGS2
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 2 ITPR3, TLR4
neuron projection 1 PTGS2
ciliary basal body 1 AKT1
cell projection 2 ATP2B1, SLC6A12
phagocytic cup 1 TLR4
Chromosome 1 HMGB1
Basolateral cell membrane 3 ATP2B1, SLC6A12, SLC9A1
[Isoform 1]: Endoplasmic reticulum membrane 1 PEMT
Presynaptic cell membrane 1 ATP2B1
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 HMGB1
secretory granule lumen 1 HMGB1
secretory granule membrane 1 ITPR3
endoplasmic reticulum lumen 1 PTGS2
transcription repressor complex 1 HMGB1
specific granule lumen 1 LYZ
tertiary granule lumen 1 LYZ
azurophil granule lumen 1 LYZ
immunological synapse 1 ATP2B1
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
platelet dense tubular network membrane 1 ITPR3
death-inducing signaling complex 1 CASP3
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
condensed chromosome 1 HMGB1
[Isoform 2]: Endoplasmic reticulum membrane 1 PEMT
transport vesicle membrane 1 ITPR3
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
photoreceptor ribbon synapse 1 ATP2B1
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
cation-transporting ATPase complex 1 SLC9A1


文献列表

  • Qiyan Lin, Xiyu Ge, Leilei Gao, Yanjun Chen, Ting Su, Menghua Ma, Huijun Wang, Cunwu Chen, Bangxing Han, Dong Liu. Betaine alleviates spermatogenic cells apoptosis of oligoasthenozoospermia rat model by up-regulating methyltransferases and affecting DNA methylation. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jul; 129(?):155713. doi: 10.1016/j.phymed.2024.155713. [PMID: 38735196]
  • Jianhua Zhao, Yuhui Xu, Haoxia Li, Wei An, Yue Yin, Bin Wang, Liping Wang, Bi Wang, Linyuan Duan, Xiaoyue Ren, Xiaojie Liang, Yajun Wang, Ru Wan, Ting Huang, Bo Zhang, Yanlong Li, Jie Luo, Youlong Cao. Metabolite-based genome-wide association studies enable the dissection of the genetic bases of flavonoids, betaine and spermidine in wolfberry (Lycium). Plant biotechnology journal. 2024 Jun; 22(6):1435-1452. doi: 10.1111/pbi.14278. [PMID: 38194521]
  • Sakthi Uma Devi Eswaran, Lalitha Sundaram, Kahkashan Perveen, Najat A Bukhari, R Z Sayyed. Osmolyte-producing microbial biostimulants regulate the growth of Arachis hypogaea L. under drought stress. BMC microbiology. 2024 May; 24(1):165. doi: 10.1186/s12866-024-03320-6. [PMID: 38745279]
  • Hongxia Zhang, Yanlin Li, Jian Ling, Jianlong Zhao, Yan Li, Zhenchuan Mao, Xinyue Cheng, Bingyan Xie. NRPS-like ATRR in Plant-Parasitic Nematodes Involved in Glycine Betaine Metabolism to Promote Parasitism. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084275. [PMID: 38673861]
  • Gaoxiao Xu, Hongyuan Pan, Liping Fan, Lifang Zhang, Jian Li, Shimei Cheng, Libing Meng, Nana Shen, Yong Liu, Yixing Li, Tengda Huang, Lei Zhou. Dietary Betaine Improves Glucose Metabolism in Obese Mice. The Journal of nutrition. 2024 Apr; 154(4):1309-1320. doi: 10.1016/j.tjnut.2024.02.025. [PMID: 38417550]
  • Viktor Filatov, Anna Sokolova, Natalya Savitskaya, Mariya Olkhovskaya, Andrey Varava, Egor Ilin, Elizaveta Patronova. Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration. Molecules (Basel, Switzerland). 2024 Mar; 29(7):. doi: 10.3390/molecules29071540. [PMID: 38611819]
  • Caleigh M Sawicki, Lorena S Pacheco, Sona Rivas-Tumanyan, Zheyi Cao, Danielle E Haslam, Liming Liang, Katherine L Tucker, Kaumudi Joshipura, Shilpa N Bhupathiraju. Association of Gut Microbiota-Related Metabolites and Type 2 Diabetes in Two Puerto Rican Cohorts. Nutrients. 2024 Mar; 16(7):. doi: 10.3390/nu16070959. [PMID: 38612993]
  • Xinping Dong, Xiaomei Ma, Zhilong Zhao, Miao Ma. Exogenous betaine enhances salt tolerance of Glycyrrhiza uralensis through multiple pathways. BMC plant biology. 2024 Mar; 24(1):165. doi: 10.1186/s12870-024-04851-w. [PMID: 38431542]
  • Daniel Leclerc, Karen E Christensen, Alaina M Reagan, Vafa Keser, Yan Luan, Olga V Malysheva, Brandi Wasek, Teodoro Bottiglieri, Marie A Caudill, Gareth R Howell, Rima Rozen. Folate Deficiency and/or the Genetic Variant Mthfr677C >T Can Drive Hepatic Fibrosis or Steatosis in Mice, in a Sex-Specific Manner. Molecular nutrition & food research. 2024 Mar; 68(5):e2300355. doi: 10.1002/mnfr.202300355. [PMID: 38327171]
  • Chengwei Wang, Hao Liu, Hu Lin, Rui Zhong, Hao Li, Jiaxin Liu, Xianglin Luo, Meng Tian. Effect of zwitterionic sulfobetaine incorporation on blood behaviours, phagocytosis, and in vivo biodistribution of pH-responsive micelles with positive charges. Journal of materials chemistry. B. 2024 Feb; 12(6):1652-1666. doi: 10.1039/d3tb02477f. [PMID: 38275277]
  • Wangwang Huang, Yizhuo Hua, Fan Wang, Jia Xu, Lv Yuan, Zhao Jing, Weimin Wang, Yuhua Zhao. Dietary betaine and/or TMAO affect hepatic lipid accumulation and glycometabolism of Megalobrama amblycephala exposed to a high-carbohydrate diet. Fish physiology and biochemistry. 2024 Feb; 50(1):59-75. doi: 10.1007/s10695-022-01160-7. [PMID: 36580207]
  • Youlan Che, Tian Xia, Hui Liu, Cong Li, Siyun Liu, Ping Ma, Qingbin Xu, Ru Zhou. Preparation of betaine injection and its therapeutic effect in pulmonary arterial hypertension. Basic & clinical pharmacology & toxicology. 2024 Feb; 134(2):219-230. doi: 10.1111/bcpt.13966. [PMID: 38009574]
  • Agata Pucek-Kaczmarek, Dominika Celary, Urszula Bazylińska. Natural-Origin Betaine Surfactants as Promising Components for the Stabilization of Lipid Carriers. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25020955. [PMID: 38256029]
  • Lingli Tian, Xiaolu Zhao, Ziying Hu, Jun Liu, Jiao Ma, Yanli Fan, Dunhua Liu. iTRAQ-based proteomics identifies proteins associated with betaine accumulation in Lycium barbarum L. Journal of proteomics. 2024 Jan; 290(?):105033. doi: 10.1016/j.jprot.2023.105033. [PMID: 37879564]
  • Jyoti Sharma, Sandeep Kumar, Vikram Kumar, Pooja Singh, Pradeep Khyalia, Sakshi Saini, Priyanka Sharma, Ajay Kumar, Asha Sharma. Stress-mitigating behavior of glycine betaine to enhance growth performance by suppressing the oxidative stress in Pb-stressed barley genotypes. Environmental science and pollution research international. 2024 Jan; 31(5):7498-7513. doi: 10.1007/s11356-023-31731-x. [PMID: 38158536]
  • Yongxiang Liao, Mengyuan Li, Hezhou Wu, Yingxiu Liao, Jialu Xin, Xinmiao Yuan, Yong Li, Aiji Wei, Xuemei Zou, Daiming Guo, Zhenzhen Xue, Guoxu Zhu, Zhaoning Wang, Peizhou Xu, Hongyu Zhang, Xiaoqiong Chen, Kangxi Du, Hao Zhou, Duo Xia, Asif Ali, Xianjun Wu. Generation of aroma in three-line hybrid rice through CRISPR/Cas9 editing of BETAINE ALDEHYDE DEHYDROGENASE2 (OsBADH2). Physiologia plantarum. 2024 Jan; 176(1):e14206. doi: 10.1111/ppl.14206. [PMID: 38356346]
  • Liang Lai, Mengyun Zhang, Chusheng Liu, Jiahuan Qu, Dongsheng Xu, Zhengjin Jiang. A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2024 Jan; 40(1):85-91. doi: 10.1007/s44211-023-00430-5. [PMID: 37843729]
  • Lauren E Louck, Kelly C Cara, Kevin Klatt, Taylor C Wallace, Mei Chung. The Relationship of Circulating Choline and Choline-Related Metabolite Levels with Health Outcomes: A Scoping Review of Genome-Wide Association Studies and Mendelian Randomization Studies. Advances in nutrition (Bethesda, Md.). 2023 Dec; 15(2):100164. doi: 10.1016/j.advnut.2023.100164. [PMID: 38128611]
  • Yuedong Shen, Wenli Zhao, Yangguang Bao, Jiayun Zhu, Lefei Jiao, Xuemei Duan, Tingting Pan, Óscar Monroig, Qicun Zhou, Min Jin. Molecular cloning and characterization of endoplasmic reticulum stress related genes grp78 and atf6α from black seabream (Acanthopagrus schlegelii) and their expressions in response to nutritional regulation. Fish physiology and biochemistry. 2023 Dec; 49(6):1115-1128. doi: 10.1007/s10695-023-01242-0. [PMID: 37855969]
  • Firoozeh Hosseini-Esfahani, Glareh Koochakpoor, Mahdieh Golzarand, Parvin Mirmiran, Fereidoun Azizi. Dietary Intakes of Choline and Betaine and Incidence of Type 2 Diabetes: Tehran Lipid and Glucose Study. Metabolic syndrome and related disorders. 2023 Dec; 21(10):573-580. doi: 10.1089/met.2023.0096. [PMID: 37816243]
  • Stéphanie Bolik, Alexander Schlaich, Tetiana Mukhina, Alberto Amato, Olivier Bastien, Emanuel Schneck, Bruno Demé, Juliette Jouhet. Lipid bilayer properties potentially contributed to the evolutionary disappearance of betaine lipids in seed plants. BMC biology. 2023 11; 21(1):275. doi: 10.1186/s12915-023-01775-z. [PMID: 38017456]
  • Muziri Mugwanya, Fahad Kimera, Anwar Abdelnaser, Hani Sewilam. Coping with Water Stress: Ameliorative Effects of Combined Treatments of Salicylic Acid and Glycine Betaine on the Biometric Traits and Water-Use Efficiency of Onion (Allium cepa) Cultivated under Deficit Drip Irrigation. Biomolecules. 2023 11; 13(11):. doi: 10.3390/biom13111634. [PMID: 38002316]
  • Dhaneshvaree Patel, Poonam Yadav, Sumeet K Singh, Sampat S Tanwar, Abhishek Sehrawat, Amit Khurana, Jasvinder S Bhatti, Umashanker Navik. Betaine alleviates doxorubicin-induced nephrotoxicity by preventing oxidative insults, inflammation, and fibrosis through the modulation of Nrf2/HO-1/NLRP3 and TGF-β expression. Journal of biochemical and molecular toxicology. 2023 Oct; ?(?):e23559. doi: 10.1002/jbt.23559. [PMID: 37840533]
  • Xueying Peng, Qiuli Wang, Duoyong Lang, Yi Li, Wenjin Zhang, Xinhui Zhang. Bacillus cereus G2 Facilitates N Cycle in Soil, Further Improves N Uptake and Assimilation, and Accelerates Proline and Glycine Betaine Metabolisms of Glycyrrhiza uralensis Subjected to Salt Stress. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.3c04936. [PMID: 37828905]
  • Ehab A Ibrahim, Noura E S Ebrahim, Gehan Z Mohamed. Effect of water stress and foliar application of chitosan and glycine betaine on lettuce. Scientific reports. 2023 Oct; 13(1):17274. doi: 10.1038/s41598-023-43992-0. [PMID: 37828035]
  • Shan Huang, Si Ying Lim, Sock Hwee Tan, Mark Y Chan, Wuzhong Ni, Sam Fong Yau Li. Targeted Plasma Metabolomics Reveals Association of Acute Myocardial Infarction Risk with the Dynamic Balance between Trimethylamine-N-oxide, Betaine, and Choline. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.2c08241. [PMID: 37781984]
  • Fatemeh Gholamian, Naser Karimi, Forouzan Gholamian, Parviz Bayat. Phycoremediation potential and agar yield of red macroalgae (Gracilaria corticata) against HEDP (hydroxyethylidene diphosphonic acid) and CAPB (cocoamidopropyl betaine) detergents and the heavy metal pollutants. Environmental science and pollution research international. 2023 Aug; ?(?):. doi: 10.1007/s11356-023-29427-3. [PMID: 37648916]
  • Hao-Long He, Guo-Shan Zhang, Shan-Feng Xiao, Hong-Hua Liu, Huan Zhong, Xiao-Rong Chang, Qiong Liu, Mi Liu. [Effects of moxibustion at "Tianshu"（ST25） and "Shangjuxu" （ST37） on colonic metabolites and inflammatory factors in rats with Crohn's disease]. Zhen ci yan jiu = Acupuncture research. 2023 Aug; 48(8):736-45. doi: 10.13702/j.1000?0607.20221276. [PMID: 37614131]
  • Nikita E Frolov, Anastasia V Shishkina, Mikhail V Vener. Specific Proton-Donor Properties of Glycine Betaine. Metric Parameters and Enthalpy of Noncovalent Interactions in its Dimer, Water Complexes and Crystalline Hydrate. International journal of molecular sciences. 2023 Aug; 24(16):. doi: 10.3390/ijms241612971. [PMID: 37629150]
  • Alessandre C Crispim, Shirley M A Crispim, Jéssica R Rocha, Jeferson S Ursulino, Roberto R Sobrinho, Viviane A Porto, Edson S Bento, Antônio E G Santana, Luiz C Caetano. Light effects on Lasiodiplodia theobromae metabolome cultured in vitro. Metabolomics : Official journal of the Metabolomic Society. 2023 08; 19(8):75. doi: 10.1007/s11306-023-02041-7. [PMID: 37580624]
  • Ensiye Soleimani, Abnoos Mokhtari Ardekani, Ehsan Fayyazishishavan, Mahdieh Abbasalizad Farhangi. The interactive relationship of dietary choline and betaine with physical activity on circulating creatine kinase (CK), metabolic and glycemic markers, and anthropometric characteristics in physically active young individuals. BMC endocrine disorders. 2023 Jul; 23(1):158. doi: 10.1186/s12902-023-01413-3. [PMID: 37491240]
  • Jelena Vladić, Strahinja Kovačević, Krunoslav Aladić, Stela Jokić, Sanja Radman, Sanja Podunavac-Kuzmanović, Ana Rita C Duarte, Igor Jerković. Innovative Strategy for Aroma Stabilization Using Green Solvents: Supercritical CO2 Extracts of Satureja montana Dispersed in Deep Eutectic Solvents. Biomolecules. 2023 07; 13(7):. doi: 10.3390/biom13071126. [PMID: 37509162]
  • Qing Li, Xiao Wang, Zhuangzhuang Sun, Yixin Wu, Maguje Masa Malkodslo, Jiakun Ge, Zihan Jing, Qin Zhou, Jian Cai, Yingxin Zhong, Mei Huang, Dong Jiang. DNA methylation levels of TaP5CS and TaBADH are associated with enhanced tolerance to PEG-induced drought stress triggered by drought priming in wheat. Plant physiology and biochemistry : PPB. 2023 Jul; 200(?):107769. doi: 10.1016/j.plaphy.2023.107769. [PMID: 37263071]
  • Tatyana V Sikorskaya. Coral Lipidome: Molecular Species of Phospholipids, Glycolipids, Betaine Lipids, and Sphingophosphonolipids. Marine drugs. 2023 May; 21(6):. doi: 10.3390/md21060335. [PMID: 37367660]
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