PCB 61 (BioDeep_00000009854)

   

Industrial Pollutants


代谢物信息卡片


2,3,4,5-Tetrachlorobiphenyl

化学式: C12H6Cl4 (289.9224)
中文名称: 2,3,4,5-四氯联苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C2=CC(=C(C(=C2Cl)Cl)Cl)Cl
InChI: InChI=1S/C12H6Cl4/c13-9-6-8(7-4-2-1-3-5-7)10(14)12(16)11(9)15/h1-6H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

3 个代谢物同义名

2,3,4,5-Tetrachlorobiphenyl; PCB 61; 2,3,4,5-Tetrachlorobiphenyl



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 CAT, CCR1, CHAT, CYP1A1, CYP2B6, HMGB1, HPGDS
Peripheral membrane protein 4 CYP1A1, CYP2B6, HK2, HMGB1
Endoplasmic reticulum membrane 5 CD4, CYP1A1, CYP1A2, CYP2B6, HSP90B1
Nucleus 3 CHAT, HMGB1, HSP90B1
cytosol 9 CAT, CCR10, CD44, CHAT, GSR, HK2, HPGDS, HSP90B1, SHB
centrosome 1 HK2
nucleoplasm 4 CCR10, HMGB1, HPGDS, SHB
Cell membrane 5 CCR1, CD4, CD44, CD8A, HMGB1
Multi-pass membrane protein 2 CCR1, SLC45A2
Synapse 1 CHAT
cell surface 3 CCR10, CD44, HMGB1
Golgi apparatus 1 CD44
mitochondrial inner membrane 1 CYP1A1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 HK2
endosome 1 HMGB1
plasma membrane 7 CCR1, CCR10, CD4, CD44, CD8A, HMGB1, SHB
Membrane 6 CAT, CCR10, CD44, HK2, HSP90B1, SLC45A2
apical plasma membrane 1 CD44
basolateral plasma membrane 1 CD44
extracellular exosome 5 CAT, CD44, GSR, HSP90B1, TTR
endoplasmic reticulum 3 CCR10, HMGB1, HSP90B1
extracellular space 3 HMGB1, IL2, TTR
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 4 CAT, CYP1A1, GSR, HK2
protein-containing complex 2 CAT, HSP90B1
intracellular membrane-bounded organelle 7 CAT, CCR10, CYP1A1, CYP1A2, CYP2B6, HK2, HPGDS
Microsome membrane 3 CYP1A1, CYP1A2, CYP2B6
Single-pass type I membrane protein 3 CD4, CD44, CD8A
Secreted 5 CD44, HK2, HMGB1, IL2, TTR
extracellular region 7 CAT, CD44, CD8A, HMGB1, HSP90B1, IL2, TTR
Mitochondrion outer membrane 1 HK2
Single-pass membrane protein 1 CD44
mitochondrial outer membrane 1 HK2
[Isoform 2]: Secreted 1 CD8A
mitochondrial matrix 2 CAT, GSR
Extracellular side 1 HMGB1
nuclear membrane 1 CCR10
external side of plasma membrane 5 CCR1, CCR10, CD4, CD8A, GSR
Melanosome membrane 1 SLC45A2
midbody 1 HSP90B1
Early endosome 2 CCR10, CD4
recycling endosome 1 CCR10
Mitochondrion inner membrane 1 CYP1A1
Membrane raft 1 CD4
focal adhesion 3 CAT, CD44, HSP90B1
Peroxisome 1 CAT
sarcoplasmic reticulum 1 HK2
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 HSP90B1
receptor complex 1 CD8A
neuron projection 1 CHAT
cell projection 1 CD44
Chromosome 1 HMGB1
cytoplasmic ribonucleoprotein granule 1 SHB
actin filament 1 CCR10
microvillus 1 CD44
Cell projection, microvillus 1 CD44
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
plasma membrane raft 1 CD8A
ficolin-1-rich granule lumen 2 CAT, HMGB1
secretory granule lumen 2 CAT, HMGB1
secretory granule membrane 1 CD44
endoplasmic reticulum lumen 2 CD4, HSP90B1
transcription repressor complex 1 HMGB1
azurophil granule lumen 1 TTR
clathrin-coated endocytic vesicle membrane 1 CD4
Sarcoplasmic reticulum lumen 1 HSP90B1
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
[Isoform 1]: Cell membrane 1 CD8A
condensed chromosome 1 HMGB1
lamellipodium membrane 1 CD44
endocytic vesicle lumen 1 HSP90B1
T cell receptor complex 2 CD4, CD8A
catalase complex 1 CAT
macrophage migration inhibitory factor receptor complex 1 CD44
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
endoplasmic reticulum chaperone complex 1 HSP90B1


文献列表

  • Tomo Daidoji, Keisuke Gozu, Hidetomo Iwano, Hiroki Inoue, Hiroshi Yokota. UDP-glucuronosyltransferase isoforms catalyzing glucuronidation of hydroxy-polychlorinated biphenyls in rat. Drug metabolism and disposition: the biological fate of chemicals. 2005 Oct; 33(10):1466-76. doi: 10.1124/dmd.105.004416. [PMID: 16006569]
  • V S Baxter-Plant, I P Mikheenko, M Robson, S J Harrad, L E Macaskie. Dehalogenation of chlorinated aromatic compounds using a hybrid bioinorganic catalyst on cells of Desulfovibrio desulfuricans. Biotechnology letters. 2004 Dec; 26(24):1885-90. doi: 10.1007/s10529-004-6039-x. [PMID: 15672233]