Sulbutiamine (BioDeep_00000009380)
代谢物信息卡片
化学式: C32H46N8O6S2 (702.2982)
中文名称: 舒布硫胺
谱图信息:
最多检出来源 not specific(not specific) %
分子结构信息
SMILES: CC(=C(CCOC(=O)C(C)C)SSC(CCOC(=O)C(C)C)=C(C)N(C=O)Cc1cnc(C)[nH]c1=N)N(C=O)Cc1cnc(C)[nH]c1=N
InChI: InChI=1S/C32H46N8O6S2/c1-19(2)31(43)45-11-9-27(21(5)39(17-41)15-25-13-35-23(7)37-29(25)33)47-48-28(10-12-46-32(44)20(3)4)22(6)40(18-42)16-26-14-36-24(8)38-30(26)34/h13-14,17-20H,9-12,15-16H2,1-8H3,(H2,33,35,37)(H2,34,36,38)/b27-21+,28-22+
描述信息
A - Alimentary tract and metabolism > A11 - Vitamins > A11D - Vitamin b1, plain and in combination with vitamin b6 and b12 > A11DA - Vitamin b1, plain
Same as: D01319
同义名列表
3 个代谢物同义名
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:31290
- KEGG: C12750
- PubChem: 3002120
- PubChem: 71124
- Metlin: METLIN69478
- DrugBank: DB13416
- ChEMBL: CHEMBL1874002
- CAS: 3286-46-2
- PMhub: MS000023159
- PubChem: 583139
- NIKKAJI: J4.424E
- KNApSAcK: 31290
分类词条
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Aman Shah Abdul Majid, Zheng Qin Yin, Dan Ji. Sulphur antioxidants inhibit oxidative stress induced retinal ganglion cell death by scavenging reactive oxygen species but influence nuclear factor (erythroid-derived 2)-like 2 signalling pathway differently.
Biological & pharmaceutical bulletin.
2013; 36(7):1095-110. doi:
10.1248/bpb.b13-00023. [PMID: 23811559] - Kui Dong Kang, Aman Shah Abdul Majid, Kyung-A Kim, Kyungsu Kang, Hong Ryul Ahn, Chu Won Nho, Sang Hoon Jung. Sulbutiamine counteracts trophic factor deprivation induced apoptotic cell death in transformed retinal ganglion cells.
Neurochemical research.
2010 Nov; 35(11):1828-39. doi:
10.1007/s11064-010-0249-5. [PMID: 20809085] - Tim Sobolevsky, Grigory Rodchenkov. Sulbutiamine in sports.
Drug testing and analysis.
2010 Nov; 2(11-12):643-6. doi:
10.1002/dta.183. [PMID: 21204296] - Naropa J Mike Craske, Warren Turner, Joseph Zammit-Maempe, Myeong Soo Lee. Qigong ameliorates symptoms of chronic fatigue: a pilot uncontrolled study.
Evidence-based complementary and alternative medicine : eCAM.
2009 Jun; 6(2):265-70. doi:
10.1093/ecam/nem088. [PMID: 18955297] - Marie-Laure Volvert, Sandrine Seyen, Marie Piette, Brigitte Evrard, Marjorie Gangolf, Jean-Christophe Plumier, Lucien Bettendorff. Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.
BMC pharmacology.
2008 Jun; 8(?):10. doi:
10.1186/1471-2210-8-10. [PMID: 18549472] - M Spedding, J P Tillement, D Morin, A Le Ridant. [Medicines interacting with mitochondria: anti-ischemic effects of trimetazidine].
Therapie.
1999 Sep; 54(5):627-35. doi:
". [PMID: 10667101] - L Bettendorff, L Weekers, P Wins, E Schoffeniels. Injection of sulbutiamine induces an increase in thiamine triphosphate in rat tissues.
Biochemical pharmacology.
1990 Dec; 40(11):2557-60. doi:
10.1016/0006-2952(90)90099-7. [PMID: 2268373] - R T Curnow, E J Rayfield, D T George, T V Zenser, F R DeRubertis. Altered hepatic glycogen metabolism and glucoregulatory hormones during sepsis.
The American journal of physiology.
1976 May; 230(5):1296-1301. doi:
10.1152/ajplegacy.1976.230.5.1296. [PMID: 5897]
