Jadomycin B (BioDeep_00000009290)

   


代谢物信息卡片


(1S)-1-[(2S)-butan-2-yl]-7-hydroxy-5-methyl-2,8,13-trioxo-1,2,8,13-tetrahydro-3aH-benzo[b][1,3]oxazolo[3,2-f]phenanthridin-12-yl 2,6-dideoxy-alpha-L-ribo-hexopyranoside

化学式: C30H31NO9 (549.1999)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(viridiplantae) 2.91%

分子结构信息

SMILES: CCC(C)C1C(=O)OC2c3cc(C)cc(O)c3C3=C(C(=O)c4c(OC5CC(O)C(O)C(C)O5)cccc4C3=O)N21
InChI: InChI=1S/C30H31NO9/c1-5-13(3)24-30(37)40-29-16-9-12(2)10-17(32)21(16)23-25(31(24)29)28(36)22-15(27(23)35)7-6-8-19(22)39-20-11-18(33)26(34)14(4)38-20/h6-10,13-14,18,20,24,26,29,32-34H,5,11H2,1-4H3/t13-,14-,18+,20-,24-,26-,29-/m0/s1

描述信息

A jadomycin that is jadomycin A in which the phenolic hydroxy group at position 12 has been converted to the corresponding 2,6-dideoxy-alpha-L-ribo-hexopyranoside, isolated from Streptomyces venezuelae. It exists as a diastereoisomeric mixture consisting of both 3aS and 3aR isomers.

同义名列表

2 个代谢物同义名

(1S)-1-[(2S)-butan-2-yl]-7-hydroxy-5-methyl-2,8,13-trioxo-1,2,8,13-tetrahydro-3aH-benzo[b][1,3]oxazolo[3,2-f]phenanthridin-12-yl 2,6-dideoxy-alpha-L-ribo-hexopyranoside; Jadomycin B



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ABCB1, ANXA5, AURKC, BCL2, BLVRB, CAT, CDK16, HPGDS, MLST8, SOD1, TXN
Peripheral membrane protein 3 ANXA5, CDK16, HSD17B6
Endoplasmic reticulum membrane 1 BCL2
Mitochondrion membrane 1 ABCG2
Nucleus 7 AURKA, AURKB, AURKC, BCL2, CDK16, SOD1, TXN
cytosol 14 AASDHPPT, ANXA5, AURKA, AURKB, BCL2, BLVRB, CAT, CDK16, GPT, HPGDS, MLST8, MTRR, SOD1, TXN
mitochondrial membrane 1 ABCG2
centrosome 1 AURKA
nucleoplasm 9 ABCG2, AURKA, AURKB, BLVRB, HPGDS, MLST8, MTRR, SOD1, TXN
Cell membrane 4 ABCB1, ABCC1, ABCG2, CDK16
Cytoplasmic side 1 CDK16
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 ABCB1, ABCC1, ABCG2
cell surface 1 ABCB1
glutamatergic synapse 1 AURKA
lysosomal membrane 1 MLST8
neuronal cell body 1 SOD1
sarcolemma 1 ANXA5
synaptic vesicle 1 CDK16
Cytoplasm, cytosol 1 AASDHPPT
Cytoplasmic vesicle, secretory vesicle 1 CDK16
plasma membrane 5 ABCB1, ABCC1, ABCG2, BLVRB, CDK16
Membrane 6 ABCB1, ABCC1, ABCG2, ANXA5, BCL2, CAT
apical plasma membrane 3 ABCB1, ABCC1, ABCG2
basolateral plasma membrane 2 ABCC1, AURKA
extracellular exosome 9 AASDHPPT, ABCB1, ABCC1, ANXA5, BLVRB, CAT, GPT, SOD1, TXN
Lysosome membrane 1 MLST8
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 BCL2, HSD17B6
extracellular space 1 SOD1
perinuclear region of cytoplasm 1 AURKA
mitochondrion 3 BCL2, CAT, SOD1
protein-containing complex 3 BCL2, CAT, SOD1
intracellular membrane-bounded organelle 4 BLVRB, CAT, HPGDS, HSD17B6
Microsome membrane 1 HSD17B6
postsynaptic density 1 AURKA
pronucleus 1 AURKA
TORC1 complex 1 MLST8
TORC2 complex 1 MLST8
Secreted 1 TXN
extracellular region 4 ANXA5, CAT, SOD1, TXN
cytoplasmic side of plasma membrane 1 CDK16
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 2 CAT, SOD1
Cell projection, cilium 1 AURKA
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 AURKA
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 ANXA5
cytoplasmic vesicle 1 SOD1
microtubule cytoskeleton 3 AURKA, AURKB, CDK16
axon cytoplasm 1 SOD1
midbody 3 AURKA, AURKB, AURKC
spindle midzone 3 AURKA, AURKB, AURKC
Apical cell membrane 2 ABCB1, ABCG2
Membrane raft 1 ABCG2
pore complex 1 BCL2
Cytoplasm, cytoskeleton, spindle 3 AURKA, AURKB, AURKC
focal adhesion 2 ANXA5, CAT
microtubule 1 AURKA
spindle 3 AURKA, AURKB, AURKC
Peroxisome 2 CAT, SOD1
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
mitochondrial intermembrane space 1 SOD1
collagen-containing extracellular matrix 1 ANXA5
lateral plasma membrane 1 ABCC1
dendrite cytoplasm 1 SOD1
Cell projection, neuron projection 1 AURKA
Zymogen granule membrane 1 ANXA5
neuron projection 2 AURKA, CDK16
ciliary basal body 1 AURKA
cilium 1 AURKA
mitotic spindle 1 AURKA
Chromosome 1 AURKB
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole 1 AURKA
Cytoplasm, cytoskeleton, cilium basal body 1 AURKA
centriole 1 AURKA
brush border membrane 1 ABCG2
condensed chromosome, centromeric region 1 AURKB
Basolateral cell membrane 1 AURKA
Cytoplasm, cytoskeleton, spindle pole 1 AURKA
Chromosome, centromere 2 AURKB, AURKC
Chromosome, centromere, kinetochore 1 AURKB
myelin sheath 1 BCL2
intermediate filament cytoskeleton 1 MTRR
basal plasma membrane 1 ABCC1
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
kinetochore 3 AURKA, AURKB, AURKC
mitotic spindle midzone 1 AURKB
mitotic spindle pole 2 AURKA, AURKB
chromosome, centromeric region 1 AURKB
vesicle membrane 1 ANXA5
axon hillock 1 AURKA
chromosome passenger complex 3 AURKA, AURKB, AURKC
germinal vesicle 1 AURKA
meiotic spindle 1 AURKA
spindle pole centrosome 3 AURKA, AURKB, AURKC
Synapse, synaptosome 1 CDK16
spindle microtubule 2 AURKB, AURKC
external side of apical plasma membrane 2 ABCB1, ABCG2
chromocenter 1 AURKB
condensed chromosome 1 AURKC
cyclin-dependent protein kinase holoenzyme complex 1 CDK16
catalase complex 1 CAT
endothelial microparticle 1 ANXA5
BAD-BCL-2 complex 1 BCL2
[Isoform A]: Cytoplasm 1 MTRR


文献列表

  • J M Jones, D F Amsbaugh, P W Stashak, B Prescott, P J Baker, D W Alling. Kinetics of the antibody response to type III pneumococcal polysaccharide. I. Evidence that suppressor cells function by inhibiting the recruitment and proliferation of antibody-producing cells. Journal of immunology (Baltimore, Md. : 1950). 1976 Mar; 116(3):647-56. doi: NULL. [PMID: 3604]