Aziridine (BioDeep_00000008803)

 

Secondary id: BioDeep_00001871724

human metabolite blood metabolite


代谢物信息卡片


Aziridine, conjugate acid

化学式: C2H5N (43.042197)
中文名称: 聚乙烯亚胺, 氮丙啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CN1
InChI: InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2

描述信息

Glucosidase, also known as ethyleneimine or azacyclopropane, is a member of the class of compounds known as aziridines. Aziridines are organic compounds containing a saturated three-member heterocycle with one amino group and two methylene groups. Glucosidase is soluble (in water) and a very strong basic compound (based on its pKa). Glucosidase can be found in soy bean and wild celery, which makes glucosidase a potential biomarker for the consumption of these food products. Glucosidases are glycoside hydrolase enzymes categorized under the EC number 3.2.1 .
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent

同义名列表

9 个代谢物同义名

Aziridine, conjugate acid; Polyethyleneimine; Dimethyleneimine; Azacyclopropane; Ethyleneimine; Ethylenimine; Glucosidase; Aziridine; EI



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Yuling Li, Yiming Wang, Kang Guo, Kuo-Feng Tseng, Xiaoqiang Zhang, Wenjian Sun. Aza-Prilezhaev Aziridination-Enabled Multidimensional Analysis of Isomeric Lipids via High-Resolution U-Shaped Mobility Analyzer-Mass Spectrometry. Analytical chemistry. 2024 May; 96(18):7111-7119. doi: 10.1021/acs.analchem.4c00481. [PMID: 38648270]
  • M Rachèl Elzes, Ine Mertens, Ondrej Sedlacek, Bart Verbraeken, Aniek C A Doensen, Maarten A Mees, Mathias Glassner, Somdeb Jana, Jos M J Paulusse, Richard Hoogenboom. Linear Poly(ethylenimine-propylenimine) Random Copolymers for Gene Delivery: From Polymer Synthesis to Efficient Transfection with High Serum Tolerance. Biomacromolecules. 2022 06; 23(6):2459-2470. doi: 10.1021/acs.biomac.2c00210. [PMID: 35499242]
  • Alexander Faussner, Matthias M Deininger, Christian Weber, Sabine Steffens. Direct addition of poly-lysine or poly-ethylenimine to the medium: A simple alternative to plate pre-coating. PloS one. 2022; 17(7):e0260173. doi: 10.1371/journal.pone.0260173. [PMID: 35802710]
  • Lijie Tang, Haiyan Kang, Kexin Duan, Mengting Guo, Gaihong Lian, Yang Wu, Yijing Li, Shuai Gao, Yanping Jiang, Jiyuan Yin, Min Liu. Effects of Three Types of Inactivation Agents on the Antibody Response and Immune Protection of Inactivated IHNV Vaccine in Rainbow Trout. Viral immunology. 2016 09; 29(7):430-5. doi: 10.1089/vim.2016.0035. [PMID: 27548006]
  • Wen Ren, Qian Zhao, Chuan Zheng, Qiong Zhao, Li Guo, Wei Huang. Efficient Synthesis of Fully Substituted Pyrrolidine-Fused 3-Spirooxindoles via 1,3-Dipolar Cycloaddition of Aziridine and 3-Ylideneoxindole. Molecules (Basel, Switzerland). 2016 Aug; 21(9):. doi: 10.3390/molecules21091113. [PMID: 27563867]
  • Jing-Yi Zhu, Xuan Zeng, Si-Yong Qin, Shuang-Shuang Wan, Hui-Zhen Jia, Ren-Xi Zhuo, Jun Feng, Xian-Zheng Zhang. Acidity-responsive gene delivery for 'superfast' nuclear translocation and transfection with high efficiency. Biomaterials. 2016 Mar; 83(?):79-92. doi: 10.1016/j.biomaterials.2016.01.003. [PMID: 26773666]
  • SamiraSadat Abolmaali, AliMohammad Tamaddon, Eskandar Kamali-Sarvestani, MohammadJavad Ashraf, Rasoul Dinarvand. Stealth Nanogels of Histinylated Poly Ethyleneimine for Sustained Delivery of Methotrexate in Collagen-Induced Arthritis Model. Pharmaceutical research. 2015 Oct; 32(10):3309-23. doi: 10.1007/s11095-015-1708-0. [PMID: 25964048]
  • Na Liu, Linling Yu, Yan Sun. Protein adsorption to poly(ethylenimine)-modified Sepharose FF: V. Complicated effects of counterions. Journal of chromatography. A. 2015 Jul; 1404(?):44-50. doi: 10.1016/j.chroma.2015.05.046. [PMID: 26054560]
  • Anna Alcaide, Amadeu Llebaria. Aziridine ring opening for the synthesis of sphingolipid analogues: inhibitors of sphingolipid-metabolizing enzymes. The Journal of organic chemistry. 2014 Apr; 79(7):2993-3029. doi: 10.1021/jo500061w. [PMID: 24641332]
  • Madhuri Das, Pranab Goswami. Direct electrochemistry of alcohol oxidase using multiwalled carbon nanotube as electroactive matrix for biosensor application. Bioelectrochemistry (Amsterdam, Netherlands). 2013 Feb; 89(?):19-25. doi: 10.1016/j.bioelechem.2012.08.007. [PMID: 23000393]
  • Dagen Zhong, Yanpeng Jiao, Yi Zhang, Wei Zhang, Nan Li, Qinhua Zuo, Qian Wang, Wei Xue, Zonghua Liu. Effects of the gene carrier polyethyleneimines on structure and function of blood components. Biomaterials. 2013 Jan; 34(1):294-305. doi: 10.1016/j.biomaterials.2012.09.060. [PMID: 23069714]
  • R E B Fitzsimmons, H Uludağ. Specific effects of PEGylation on gene delivery efficacy of polyethylenimine: interplay between PEG substitution and N/P ratio. Acta biomaterialia. 2012 Nov; 8(11):3941-55. doi: 10.1016/j.actbio.2012.07.015. [PMID: 22820308]
  • Jeong-Hun Kang, Yoichi Tachibana, Satoshi Obika, Mariko Harada-Shiba, Tetsuji Yamaoka. Efficient reduction of serum cholesterol by combining a liver-targeted gene delivery system with chemically modified apolipoprotein B siRNA. Journal of controlled release : official journal of the Controlled Release Society. 2012 Oct; 163(2):119-24. doi: 10.1016/j.jconrel.2012.08.030. [PMID: 22974833]
  • Chongbo Sun, Tian Tang, Hasan Uludağ. Probing the effects of lipid substitution on polycation mediated DNA aggregation: a molecular dynamics simulations study. Biomacromolecules. 2012 Sep; 13(9):2982-8. doi: 10.1021/bm301045b. [PMID: 22852998]
  • Enyu Zhao, Zhixia Zhao, Jiancheng Wang, Chunhui Yang, Chengjun Chen, Lingyan Gao, Qiang Feng, Wenjie Hou, Mingyuan Gao, Qiang Zhang. Surface engineering of gold nanoparticles for in vitro siRNA delivery. Nanoscale. 2012 Aug; 4(16):5102-9. doi: 10.1039/c2nr31290e. [PMID: 22782309]
  • Surendra Nimesh. Recent patents in siRNA delivery employing nanoparticles as delivery vectors. Recent patents on DNA & gene sequences. 2012 Aug; 6(2):91-7. doi: 10.2174/187221512801327406. [PMID: 22670609]
  • Sara Bersani, Stefano Salmaso, Francesca Mastrotto, Elena Ravazzolo, Alessandra Semenzato, Paolo Caliceti. Star-like oligo-arginyl-maltotriosyl derivatives as novel cell-penetrating enhancers for the intracellular delivery of colloidal therapeutic systems. Bioconjugate chemistry. 2012 Jul; 23(7):1415-25. doi: 10.1021/bc200666u. [PMID: 22709433]
  • You-Kyoung Kim, Jung-Taek Kwon, Hu-Lin Jiang, Yun-Jaie Choi, Myung-Haing Cho, Chong-Su Cho. Kidney-specific peptide-conjugated poly(ester amine) for the treatment of kidney fibrosis. Journal of nanoscience and nanotechnology. 2012 Jul; 12(7):5149-54. doi: 10.1166/jnn.2012.6372. [PMID: 22966536]
  • Bin Yang, Yun-xia Sun, Wen-jie Yi, Juan Yang, Chen-wei Liu, Han Cheng, Jun Feng, Xian-zheng Zhang, Ren-xi Zhuo. A linear-dendritic cationic vector for efficient DNA grasp and delivery. Acta biomaterialia. 2012 Jul; 8(6):2121-32. doi: 10.1016/j.actbio.2012.02.013. [PMID: 22370448]
  • Sushil K Tripathi, Ritu Goyal, Mahendra P Kashyap, Aditya B Pant, Wahajul Haq, Pradeep Kumar, Kailash C Gupta. Depolymerized chitosans functionalized with bPEI as carriers of nucleic acids and tuftsin-tethered conjugate for macrophage targeting. Biomaterials. 2012 Jun; 33(16):4204-19. doi: 10.1016/j.biomaterials.2012.02.035. [PMID: 22417621]
  • Young Tag Ko, Ulrich Bickel. Liposome-encapsulated polyethylenimine/oligonucleotide polyplexes prepared by reverse-phase evaporation technique. AAPS PharmSciTech. 2012 Jun; 13(2):373-8. doi: 10.1208/s12249-012-9757-8. [PMID: 22328240]
  • Meng Zheng, Zhihong Zhong, Lei Zhou, Fenghua Meng, Rui Peng, Zhiyuan Zhong. Poly(ethylene oxide) grafted with short polyethylenimine gives DNA polyplexes with superior colloidal stability, low cytotoxicity, and potent in vitro gene transfection under serum conditions. Biomacromolecules. 2012 Mar; 13(3):881-8. doi: 10.1021/bm2017965. [PMID: 22339316]
  • Hilda T R Wiogo, May Lim, Volga Bulmus, Lucía Gutiérrez, Robert C Woodward, Rose Amal. Insight into serum protein interactions with functionalized magnetic nanoparticles in biological media. Langmuir : the ACS journal of surfaces and colloids. 2012 Mar; 28(9):4346-56. doi: 10.1021/la204740t. [PMID: 22313424]
  • Carsten Rudolph, Joseph Rosenecker. Formation of solid lipid nanoparticle (SLN)-gene vector complexes for transfection of mammalian cells in vitro. Cold Spring Harbor protocols. 2012 Mar; 2012(3):357-60. doi: 10.1101/pdb.prot068122. [PMID: 22383641]
  • Young Hun Kim, Yong Man Lee, Jun Young Lee, Min Jae Ko, Pil J Yoo. Hierarchical nanoflake surface driven by spontaneous wrinkling of polyelectrolyte/metal complexed films. ACS nano. 2012 Feb; 6(2):1082-93. doi: 10.1021/nn203226k. [PMID: 22236171]
  • Shuo-Li Sun, Yu-Lun Lo, Hsing-Yin Chen, Li-Fang Wang. Hybrid polyethylenimine and polyacrylic acid-bound iron oxide as a magnetoplex for gene delivery. Langmuir : the ACS journal of surfaces and colloids. 2012 Feb; 28(7):3542-52. doi: 10.1021/la204529u. [PMID: 22242960]
  • Wei Xia, Peijun Wang, Chao Lin, Zhuoquan Li, Xiaolong Gao, Guoliang Wang, Xiaohu Zhao. Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo. Journal of controlled release : official journal of the Controlled Release Society. 2012 Feb; 157(3):427-36. doi: 10.1016/j.jconrel.2011.10.011. [PMID: 22036880]
  • Jun Jin, Fang Yang, Fengwei Zhang, Wuquan Hu, Shao-bo Sun, Jiantai Ma. 2, 2'-(Phenylazanediyl) diacetic acid modified Fe3O4@PEI for selective removal of cadmium ions from blood. Nanoscale. 2012 Feb; 4(3):733-6. doi: 10.1039/c2nr11481j. [PMID: 22189502]
  • Manfred Ogris, Ernst Wagner. Synthesis of linear polyethylenimine and use in transfection. Cold Spring Harbor protocols. 2012 Feb; 2012(2):246-50. doi: 10.1101/pdb.prot067868. [PMID: 22301655]
  • Jagbir Singh, Deborah Michel, Jackson M Chitanda, Ronald E Verrall, Ildiko Badea. Evaluation of cellular uptake and intracellular trafficking as determining factors of gene expression for amino acid-substituted gemini surfactant-based DNA nanoparticles. Journal of nanobiotechnology. 2012 Feb; 10(?):7. doi: 10.1186/1477-3155-10-7. [PMID: 22296763]
  • Dong-Wook Ryu, Hyun Ah Kim, Jae Hwan Ryu, Dong Yun Lee, Minhyung Lee. Amphiphilic peptides with arginine and valine residues as siRNA carriers. Journal of cellular biochemistry. 2012 Feb; 113(2):619-28. doi: 10.1002/jcb.23389. [PMID: 21956817]
  • Shashank R Sirsi, Sonia L Hernandez, Lukasz Zielinski, Henning Blomback, Adel Koubaa, Milo Synder, Shunichi Homma, Jessica J Kandel, Darrell J Yamashiro, Mark A Borden. Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. Journal of controlled release : official journal of the Controlled Release Society. 2012 Jan; 157(2):224-34. doi: 10.1016/j.jconrel.2011.09.071. [PMID: 21945680]
  • Ritu Goyal, Sushil K Tripathi, Esther Vazquez, Pradeep Kumar, Kailash C Gupta. Biodegradable poly(vinyl alcohol)-polyethylenimine nanocomposites for enhanced gene expression in vitro and in vivo. Biomacromolecules. 2012 Jan; 13(1):73-83. doi: 10.1021/bm201157f. [PMID: 22145672]
  • Bo Li, Hui Xu, Zhen Li, Mingfei Yao, Meng Xie, Haijun Shen, Song Shen, Xinshi Wang, Yi Jin. Bypassing multidrug resistance in human breast cancer cells with lipid/polymer particle assemblies. International journal of nanomedicine. 2012; 7(?):187-97. doi: 10.2147/ijn.s27864. [PMID: 22275834]
  • Joceline J Karimpil, J S Melo, S F D'Souza. Immobilization of lipase on cotton cloth using the layer-by-layer self-assembly technique. International journal of biological macromolecules. 2012 Jan; 50(1):300-2. doi: 10.1016/j.ijbiomac.2011.10.019. [PMID: 22062119]
  • Leire García, Koldo Urbiola, Nejat Düzgüneş, Conchita Tros de Ilarduya. Lipopolyplexes as nanomedicines for therapeutic gene delivery. Methods in enzymology. 2012; 509(?):327-38. doi: 10.1016/b978-0-12-391858-1.00016-2. [PMID: 22568913]
  • Gemma Navarro, Rupa R Sawant, Swati Biswas, Sean Essex, Conchita Tros de Ilarduya, Vladimir P Torchilin. P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells. Nanomedicine (London, England). 2012 Jan; 7(1):65-78. doi: 10.2217/nnm.11.93. [PMID: 22191778]
  • Chengchu Liu, Qing Zhu, Wenhui Wu, Xiaolin Xu, Xiaoyu Wang, Shen Gao, Kehai Liu. Degradable copolymer based on amphiphilic N-octyl-N-quatenary chitosan and low-molecular weight polyethylenimine for gene delivery. International journal of nanomedicine. 2012; 7(?):5339-50. doi: 10.2147/ijn.s36179. [PMID: 23071395]
  • Nittaya Tresilwised, Pimolpan Pithayanukul, Per Sonne Holm, Ulrike Schillinger, Christian Plank, Olga Mykhaylyk. Effects of nanoparticle coatings on the activity of oncolytic adenovirus-magnetic nanoparticle complexes. Biomaterials. 2012 Jan; 33(1):256-69. doi: 10.1016/j.biomaterials.2011.09.028. [PMID: 21978891]
  • Wei Wang, Fang Zhou, Linfu Ge, Ximin Liu, Fansheng Kong. Transferrin-PEG-PE modified dexamethasone conjugated cationic lipid carrier mediated gene delivery system for tumor-targeted transfection. International journal of nanomedicine. 2012; 7(?):2513-22. doi: 10.2147/ijn.s31915. [PMID: 22679364]
  • Yan Jin, Zheng Liu, Wei Cao, Xinying Ma, Yihui Fan, Yang Yu, Jing Bai, Feng Chen, Jesusa Rosales, Ki-Young Lee, Songbin Fu. Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression. PloS one. 2012; 7(2):e30419. doi: 10.1371/journal.pone.0030419. [PMID: 22319568]
  • Thérèse Keravis, Fanny Monneaux, Issaka Yougbaré, Lucien Gazi, Jean-Jacques Bourguignon, Sylviane Muller, Claire Lugnier. Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor. PloS one. 2012; 7(1):e28899. doi: 10.1371/journal.pone.0028899. [PMID: 22247763]
  • Hongmei Song, Gang Wang, Bin He, Li Li, Caixia Li, Yusi Lai, Xianghui Xu, Zhongwei Gu. Cationic lipid-coated PEI/DNA polyplexes with improved efficiency and reduced cytotoxicity for gene delivery into mesenchymal stem cells. International journal of nanomedicine. 2012; 7(?):4637-48. doi: 10.2147/ijn.s33923. [PMID: 22942645]
  • Nobutaka Hanagata. Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system. International journal of nanomedicine. 2012; 7(?):2181-95. doi: 10.2147/ijn.s30197. [PMID: 22619554]
  • Sana Abbasi, Arghya Paul, Wei Shao, Satya Prakash. Cationic albumin nanoparticles for enhanced drug delivery to treat breast cancer: preparation and in vitro assessment. Journal of drug delivery. 2012; 2012(?):686108. doi: 10.1155/2012/686108. [PMID: 22187654]
  • Li Li, Yubin Wu, Changshan Wang, Weiguo Zhang. Inhibition of PAX2 gene expression by siRNA (polyethylenimine) in experimental model of obstructive nephropathy. Renal failure. 2012; 34(10):1288-96. doi: 10.3109/0886022x.2012.723662. [PMID: 23078635]
  • Wei Li, Huafei Li, Jinfeng Li, Huajing Wang, He Zhao, Li Zhang, Yu Xia, Zengwei Ye, Jie Gao, Jianxin Dai, Hao Wang, Yajun Guo. Self-assembled supramolecular nano vesicles for safe and highly efficient gene delivery to solid tumors. International journal of nanomedicine. 2012; 7(?):4661-77. doi: 10.2147/ijn.s34675. [PMID: 22977303]
  • Meng Zheng, Yinan Zhong, Fenghua Meng, Rui Peng, Zhiyuan Zhong. Lipoic acid modified low molecular weight polyethylenimine mediates nontoxic and highly potent in vitro gene transfection. Molecular pharmaceutics. 2011 Dec; 8(6):2434-43. doi: 10.1021/mp2003797. [PMID: 21923163]
  • Mohammad Ariful Islam, Cheol-Heui Yun, Yun-Jaie Choi, Ji-Young Shin, Rohidas Arote, Hu-Lin Jiang, Sang-Kee Kang, Jae-Woon Nah, In-Kyu Park, Myung-Haing Cho, Chong-Su Cho. Accelerated gene transfer through a polysorbitol-based transporter mechanism. Biomaterials. 2011 Dec; 32(36):9908-24. doi: 10.1016/j.biomaterials.2011.09.013. [PMID: 21959011]
  • Cameron W Evans, Melinda Fitzgerald, Tristan D Clemons, Michael J House, Benjamin S Padman, Jeremy A Shaw, Martin Saunders, Alan R Harvey, Bogdan Zdyrko, Igor Luzinov, Gabriel A Silva, Sarah A Dunlop, K Swaminathan Iyer. Multimodal analysis of PEI-mediated endocytosis of nanoparticles in neural cells. ACS nano. 2011 Nov; 5(11):8640-8. doi: 10.1021/nn2022149. [PMID: 22003894]
  • Sana Abbasi, Arghya Paul, Satya Prakash. Investigation of siRNA-loaded polyethylenimine-coated human serum albumin nanoparticle complexes for the treatment of breast cancer. Cell biochemistry and biophysics. 2011 Nov; 61(2):277-87. doi: 10.1007/s12013-011-9201-9. [PMID: 21556941]
  • Yun He, Yang Bi, Yi Hua, Dongyao Liu, Sheng Wen, Qiang Wang, Mingyong Li, Jing Zhu, Tao Lin, Dawei He, Xuliang Li, Zhigang Wang, Guanghui Wei. Ultrasound microbubble-mediated delivery of the siRNAs targeting MDR1 reduces drug resistance of yolk sac carcinoma L2 cells. Journal of experimental & clinical cancer research : CR. 2011 Oct; 30(?):104. doi: 10.1186/1756-9966-30-104. [PMID: 22035293]
  • Jiefu Jin, Yan-Juan Gu, Cornelia Wing-Yin Man, Jinping Cheng, Zhenhua Xu, Yue Zhang, Huaishan Wang, Vien Hoi-Yi Lee, Shuk Han Cheng, Wing-Tak Wong. Polymer-coated NaYF₄:Yb³⁺, Er³⁺ upconversion nanoparticles for charge-dependent cellular imaging. ACS nano. 2011 Oct; 5(10):7838-47. doi: 10.1021/nn201896m. [PMID: 21905691]
  • Sejin Son, Do Won Hwang, Kaushik Singha, Ji Hoon Jeong, Tae Gwan Park, Dong Soo Lee, Won Jong Kim. RVG peptide tethered bioreducible polyethylenimine for gene delivery to brain. Journal of controlled release : official journal of the Controlled Release Society. 2011 Oct; 155(1):18-25. doi: 10.1016/j.jconrel.2010.08.011. [PMID: 20800628]
  • Hamidreza Montazeri Aliabadi, Breanne Landry, Parvin Mahdipoor, Hasan Uludağ. Induction of apoptosis by survivin silencing through siRNA delivery in a human breast cancer cell line. Molecular pharmaceutics. 2011 Oct; 8(5):1821-30. doi: 10.1021/mp200176v. [PMID: 21838308]
  • Tetsuro Tomiyama, Riki Toita, Jeong-Hun Kang, Haruka Koga, Shujiro Shiosaki, Takeshi Mori, Takuro Niidome, Yoshiki Katayama. Effect of introduction of chondroitin sulfate into polymer-peptide conjugate responding to intracellular signals. Nanoscale research letters. 2011 Sep; 6(1):532. doi: 10.1186/1556-276x-6-532. [PMID: 21961843]
  • Hui-Yi Xue, Ho-Lun Wong. Solid lipid-PEI hybrid nanocarrier: an integrated approach to provide extended, targeted, and safer siRNA therapy of prostate cancer in an all-in-one manner. ACS nano. 2011 Sep; 5(9):7034-47. doi: 10.1021/nn201659z. [PMID: 21838301]
  • Abderrahim Aissaoui, Mohamed Chami, Mahamoud Hussein, Andrew D Miller. Efficient topical delivery of plasmid DNA to lung in vivo mediated by putative triggered, PEGylated pDNA nanoparticles. Journal of controlled release : official journal of the Controlled Release Society. 2011 Sep; 154(3):275-84. doi: 10.1016/j.jconrel.2011.06.017. [PMID: 21699935]
  • Ritu Goyal, S K Tripathi, Shilpa Tyagi, K Ravi Ram, K M Ansari, Y Shukla, D Kar Chowdhuri, Pradeep Kumar, K C Gupta. Gellan gum blended PEI nanocomposites as gene delivery agents: evidences from in vitro and in vivo studies. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2011 Sep; 79(1):3-14. doi: 10.1016/j.ejpb.2011.01.009. [PMID: 21272636]
  • Jung Gyu Woo, Na Young Kim, Jai Myung Yang, Sungho Shin. Biodistribution and blood clearance of plasmid DNA administered in arginine peptide complexes. Genetic vaccines and therapy. 2011 Aug; 9(?):13. doi: 10.1186/1479-0556-9-13. [PMID: 21849058]
  • Shan-shan Liu, Xiang-mei Chen, Hong-xia Zheng, Shu-liang Shi, Yu Li. Knockdown of Rab5a expression decreases cancer cell motility and invasion through integrin-mediated signaling pathway. Journal of biomedical science. 2011 Aug; 18(?):58. doi: 10.1186/1423-0127-18-58. [PMID: 21849022]
  • Michael Kishko, Mohan Somasundaran, Frank Brewster, John L Sullivan, Paul R Clapham, Katherine Luzuriaga. Genotypic and functional properties of early infant HIV-1 envelopes. Retrovirology. 2011 Aug; 8(?):67. doi: 10.1186/1742-4690-8-67. [PMID: 21843318]
  • Janjira Intra, Aliasger K Salem. Rational design, fabrication, characterization and in vitro testing of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells. Journal of drug targeting. 2011 Jul; 19(6):393-408. doi: 10.3109/1061186x.2010.504263. [PMID: 20681752]
  • Hyun A Song, Chi Soo Kang, Kwamena E Baidoo, Diane E Milenic, Yunwei Chen, Anzhi Dai, M W Brechbiel, Hyun-Soon Chong. Efficient bifunctional decadentate ligand 3p-C-DEPA for targeted α-radioimmunotherapy applications. Bioconjugate chemistry. 2011 Jun; 22(6):1128-35. doi: 10.1021/bc100586y. [PMID: 21604692]
  • Xiaojuan Yang, Yong Peng, Bo Yu, Jianhua Yu, Chenguang Zhou, Yicheng Mao, L James Lee, Robert J Lee. A covalently stabilized lipid-polycation-DNA (sLPD) vector for antisense oligonucleotide delivery. Molecular pharmaceutics. 2011 Jun; 8(3):709-15. doi: 10.1021/mp100272k. [PMID: 21366344]
  • Yen-Ku Liu, Yu-Ling Lin, Chia-Hung Chen, Ching-Min Lin, Kuan-Lun Ma, Fu-Hsuan Chou, Jin-Sheng Tsai, Hsin-Yu Lin, Fu-Rong Chen, Tian-Lu Cheng, Chia-Ching Chang, Kuang-Wen Liao. A unique and potent protein binding nature of liposome containing polyethylenimine and polyethylene glycol: a nondisplaceable property. Biotechnology and bioengineering. 2011 Jun; 108(6):1318-27. doi: 10.1002/bit.23048. [PMID: 21192002]
  • Fengwen Zhang, Trinity Zang, Sam J Wilson, Marc C Johnson, Paul D Bieniasz. Clathrin facilitates the morphogenesis of retrovirus particles. PLoS pathogens. 2011 Jun; 7(6):e1002119. doi: 10.1371/journal.ppat.1002119. [PMID: 21738476]
  • Jian-Ping Yang, Tatiana Cirico, Federico Katzen, Todd C Peterson, Wieslaw Kudlicki. Cell-free synthesis of a functional G protein-coupled receptor complexed with nanometer scale bilayer discs. BMC biotechnology. 2011 May; 11(?):57. doi: 10.1186/1472-6750-11-57. [PMID: 21605442]
  • Zhizhong Xu, Guobo Shen, Xiangying Xia, Xinyu Zhao, Peng Zhang, Huanhuan Wu, Qingfa Guo, Zhiyong Qian, Yuquan Wei, Shufang Liang. Comparisons of three polyethyleneimine-derived nanoparticles as a gene therapy delivery system for renal cell carcinoma. Journal of translational medicine. 2011 Apr; 9(?):46. doi: 10.1186/1479-5876-9-46. [PMID: 21513541]
  • ChoonSeok Oh, Jason Price, Melinda A Brindley, Mark P Widrlechner, Luping Qu, Joe-Ann McCoy, Patricia Murphy, Cathy Hauck, Wendy Maury. Inhibition of HIV-1 infection by aqueous extracts of Prunella vulgaris L. Virology journal. 2011 Apr; 8(?):188. doi: 10.1186/1743-422x-8-188. [PMID: 21513560]
  • M N Shuaibu, M S Cherif, T Kurosaki, G K Helegbe, M Kikuchi, T Yanagi, H Sasaki, K Hirayama. Effect of nanoparticle coating on the immunogenicity of plasmid DNA vaccine encoding P. yoelii MSP-1 C-terminal. Vaccine. 2011 Apr; 29(17):3239-47. doi: 10.1016/j.vaccine.2011.02.033. [PMID: 21354479]
  • Yuhe Wang, Meng Zheng, Fenghua Meng, Jing Zhang, Rui Peng, Zhiyuan Zhong. Branched polyethylenimine derivatives with reductively cleavable periphery for safe and efficient in vitro gene transfer. Biomacromolecules. 2011 Apr; 12(4):1032-40. doi: 10.1021/bm101364f. [PMID: 21332180]
  • Ka Yu Siu, Mei Kuen Yu, Xinggang Wu, Min Zong, Michael G Roth, Hsiao Chang Chan, Sidney Yu. The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1. PloS one. 2011 Apr; 6(4):e18458. doi: 10.1371/journal.pone.0018458. [PMID: 21483700]
  • Viola B Morris, Chandra P Sharma. Folate mediated l-arginine modified oligo (alkylaminosiloxane) graft poly (ethyleneimine) for tumor targeted gene delivery. Biomaterials. 2011 Apr; 32(11):3030-41. doi: 10.1016/j.biomaterials.2010.11.048. [PMID: 21256583]
  • Suet Ping Wong, Orestis Argyros, Steven J Howe, Richard P Harbottle. Systemic gene transfer of polyethylenimine (PEI)-plasmid DNA complexes to neonatal mice. Journal of controlled release : official journal of the Controlled Release Society. 2011 Mar; 150(3):298-306. doi: 10.1016/j.jconrel.2010.12.010. [PMID: 21192993]
  • Richard B Rothman, Jean L Cadet, Christina M Dersch, Michael T McCoy, Elin Lehrmann, Kevin G Becker, Michael Bader, Natalia Alenina, Michael H Baumann. Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension. PloS one. 2011 Mar; 6(3):e17735. doi: 10.1371/journal.pone.0017735. [PMID: 21464983]
  • Jennifer M Johnston, Mahalaxmi Aburi, Davide Provasi, Andrea Bortolato, Eneko Urizar, Nevin A Lambert, Jonathan A Javitch, Marta Filizola. Making structural sense of dimerization interfaces of delta opioid receptor homodimers. Biochemistry. 2011 Mar; 50(10):1682-90. doi: 10.1021/bi101474v. [PMID: 21261298]
  • Anitha M Thomas, Anita I Kapanen, Jennifer I Hare, Euan Ramsay, Katarina Edwards, Göran Karlsson, Marcel B Bally. Development of a liposomal nanoparticle formulation of 5-fluorouracil for parenteral administration: formulation design, pharmacokinetics and efficacy. Journal of controlled release : official journal of the Controlled Release Society. 2011 Mar; 150(2):212-9. doi: 10.1016/j.jconrel.2010.11.018. [PMID: 21094191]
  • E Salva, S O Turan, J Akbuğa. Increased in vitro Cell Proliferation by Chitosan/pGM-CSF Complexes. Indian journal of pharmaceutical sciences. 2011 Mar; 73(2):131-8. doi: 10.4103/0250-474x.91569. [PMID: 22303054]
  • Lea Torrieri-Dramard, Bénédicte Lambrecht, Helena Lage Ferreira, Thierry Van den Berg, David Klatzmann, Bertrand Bellier. Intranasal DNA vaccination induces potent mucosal and systemic immune responses and cross-protective immunity against influenza viruses. Molecular therapy : the journal of the American Society of Gene Therapy. 2011 Mar; 19(3):602-11. doi: 10.1038/mt.2010.222. [PMID: 20959813]
  • Chunhua Fu, Xiaoli Sun, Donghua Liu, Zhijing Chen, Zaijun Lu, Na Zhang. Biodegradable tri-block copolymer poly(lactic acid)-poly(ethylene glycol)-poly(l-lysine)(PLA-PEG-PLL) as a non-viral vector to enhance gene transfection. International journal of molecular sciences. 2011 Feb; 12(2):1371-88. doi: 10.3390/ijms12021371. [PMID: 21541064]
  • Eun-Joong Kim, Hee-Jeong Cho, Daeui Park, Ji Yeon Kim, Young Bong Kim, Tae Gwan Park, Chang-Koo Shim, Yu-Kyoung Oh. Antifibrotic effect of MMP13-encoding plasmid DNA delivered using polyethylenimine shielded with hyaluronic acid. Molecular therapy : the journal of the American Society of Gene Therapy. 2011 Feb; 19(2):355-61. doi: 10.1038/mt.2010.262. [PMID: 21139571]
  • Thomas Rimmelé, John A Kellum. Clinical review: blood purification for sepsis. Critical care (London, England). 2011; 15(1):205. doi: 10.1186/cc9411. [PMID: 21371356]
  • Manoj B Menon, Alexey Kotlyarov, Matthias Gaestel. SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition. PloS one. 2011; 6(8):e23054. doi: 10.1371/journal.pone.0023054. [PMID: 21853067]
  • Sarantis Giatrellis, George Nounesis. Nucleic acid-lipid membrane interactions studied by DSC. Journal of pharmacy & bioallied sciences. 2011 Jan; 3(1):70-6. doi: 10.4103/0975-7406.76470. [PMID: 21430956]
  • Zhiwen Zhang, Xiaoling Fang, Junguo Hao, Yajuan Li, Xianyi Sha. Triolein-based polycation lipid nanocarrier for efficient gene delivery: characteristics and mechanism. International journal of nanomedicine. 2011; 6(?):2235-44. doi: 10.2147/ijn.s24720. [PMID: 22114487]
  • Chunxiang Xu, Lu Zhao, Xiao Pan, Jozef Samaj. Developmental localization and methylesterification of pectin epitopes during somatic embryogenesis of banana (Musa spp. AAA). PloS one. 2011; 6(8):e22992. doi: 10.1371/journal.pone.0022992. [PMID: 21826225]
  • Shige Wang, Shihui Wen, Mingwu Shen, Rui Guo, Xueyan Cao, Jianhua Wang, Xiangyang Shi. Aminopropyltriethoxysilane-mediated surface functionalization of hydroxyapatite nanoparticles: synthesis, characterization, and in vitro toxicity assay. International journal of nanomedicine. 2011; 6(?):3449-59. doi: 10.2147/ijn.s27166. [PMID: 22267929]
  • Anna Fendyur, Noa Mazurski, Joseph Shappir, Micha E Spira. Formation of Essential Ultrastructural Interface between Cultured Hippocampal Cells and Gold Mushroom-Shaped MEA- Toward 'IN-CELL' Recordings from Vertebrate Neurons. Frontiers in neuroengineering. 2011; 4(?):14. doi: 10.3389/fneng.2011.00014. [PMID: 22163219]
  • Andrea Nolte, Tobias Walker, Martina Schneider, Oya Kray, Meltem Avci-Adali, Gerhard Ziemer, Hans Peter Wendel. Small-interfering RNA-eluting surfaces as a novel concept for intravascular local gene silencing. Molecular medicine (Cambridge, Mass.). 2011; 17(11-12):1213-22. doi: 10.2119/molmed.2011.00143. [PMID: 21792480]
  • Victoria Prieto-Echagüe, Azad Gucwa, Deborah A Brown, W Todd Miller. Regulation of Ack1 localization and activity by the amino-terminal SAM domain. BMC biochemistry. 2010 Oct; 11(?):42. doi: 10.1186/1471-2091-11-42. [PMID: 20979614]
  • R Jeremy Nichols, Nicolas Dzamko, Nicholas A Morrice, David G Campbell, Maria Deak, Alban Ordureau, Thomas Macartney, Youren Tong, Jie Shen, Alan R Prescott, Dario R Alessi. 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. The Biochemical journal. 2010 Sep; 430(3):393-404. doi: 10.1042/bj20100483. [PMID: 20642453]
  • Xiaowen Ji, Fanggui Ye, Pingtan Lin, Shulin Zhao. Immobilized capillary adenosine deaminase microreactor for inhibitor screening in natural extracts by capillary electrophoresis. Talanta. 2010 Sep; 82(4):1170-4. doi: 10.1016/j.talanta.2010.06.029. [PMID: 20801314]
  • Sarosh R Irani, Sian Alexander, Patrick Waters, Kleopas A Kleopa, Philippa Pettingill, Luigi Zuliani, Elior Peles, Camilla Buckley, Bethan Lang, Angela Vincent. Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia. Brain : a journal of neurology. 2010 Sep; 133(9):2734-48. doi: 10.1093/brain/awq213. [PMID: 20663977]
  • Paolo G V Martini, Lynette C Cook, Scott Alderucci, Angela W Norton, Dianna M Lundberg, Susan M Fish, Knut Langsetmo, Göran Jönsson, Christian Lood, Birgitta Gullstrand, Kate J Zaleski, Nancy Savioli, Jason Lottherand, Charles Bedard, John Gill, Michael F Concino, Michael W Heartlein, Lennart Truedsson, Jan L Powell, Arthur O Tzianabos. Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases. BMC immunology. 2010 Aug; 11(?):43. doi: 10.1186/1471-2172-11-43. [PMID: 20727163]
  • Sarosh R Irani, Katarzyna Bera, Patrick Waters, Luigi Zuliani, Susan Maxwell, Michael S Zandi, Manuel A Friese, Ian Galea, Dimitri M Kullmann, David Beeson, Bethan Lang, Christian G Bien, Angela Vincent. N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes. Brain : a journal of neurology. 2010 Jun; 133(Pt 6):1655-67. doi: 10.1093/brain/awq113. [PMID: 20511282]
  • Aiqun Hu, Xianghua Wu, Zonghai Li, Huamao Wang, Jingjun Li, Ming Yao, Xianlian Chen, Shumin Qu, Yuhong Xu, Jianren Gu. A novel gene delivery system targeting Tie2 for cancer gene therapy. Anticancer research. 2010 Jun; 30(6):1999-2004. doi: NULL. [PMID: 20651343]
  • Gaelle Creusat, Anne-Sophie Rinaldi, Etienne Weiss, Rkia Elbaghdadi, Jean-Serge Remy, Rita Mulherkar, Guy Zuber. Proton sponge trick for pH-sensitive disassembly of polyethylenimine-based siRNA delivery systems. Bioconjugate chemistry. 2010 May; 21(5):994-1002. doi: 10.1021/bc100010k. [PMID: 20481503]
  • Chu Hu, Qi Peng, Fujie Chen, Zhenlin Zhong, Renxi Zhuo. Low molecular weight polyethylenimine conjugated gold nanoparticles as efficient gene vectors. Bioconjugate chemistry. 2010 May; 21(5):836-43. doi: 10.1021/bc900374d. [PMID: 20438071]