2-Butanone (BioDeep_00000875154)

Main id: BioDeep_00000004171

 

PANOMIX_OTCML-2023


代谢物信息卡片


Methyl ethyl ketone

化学式: C4H8O (72.0575)
中文名称: 甲乙酮, 甲基乙基酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(=O)C
InChI: InChI=1S/C4H8O/c1-3-4(2)5/h3H2,1-2H3

描述信息

A dialkyl ketone that is a four-carbon ketone carrying a single keto- group at position C-2.
Butanone, also known as methyl ethyl ketone or mek, is a member of the class of compounds known as ketones. Ketones are organic compounds in which a carbonyl group is bonded to two carbon atoms R2C=O (neither R may be a hydrogen atom). Ketones that have one or more alpha-hydrogen atoms undergo keto-enol tautomerization, the tautomer being an enol. Thus, butanone is considered to be an oxygenated hydrocarbon lipid molecule. Butanone is soluble (in water) and an extremely weak acidic compound (based on its pKa). Butanone is an acetone, camphor, and ethereal tasting compound and can be found in a number of food items such as arctic blackberry, onion-family vegetables, sweet orange, and devilfish, which makes butanone a potential biomarker for the consumption of these food products. Butanone can be found primarily in blood, feces, saliva, and urine, as well as in human pancreas and stratum corneum tissues. Moreover, butanone is found to be associated with alcoholism. Butanone is a non-carcinogenic (not listed by IARC) potentially toxic compound.

同义名列表

5 个代谢物同义名

Methyl ethyl ketone; Butan-2-one; 2-Butanone; Methyl ethyl ketone; Methyl ethyl ketone



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(4)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 CTNNB1, FGF2, MAP2K2, MARK2, MCL1, PIK3R6, PTEN, RAC1, RPS6KB1, STAT5A
Peripheral membrane protein 2 MAP2K2, PIK3R6
Endosome membrane 1 NTRK1
Endoplasmic reticulum membrane 1 RAC1
Nucleus 10 CTNNB1, FGF2, MAP2K2, MCL1, MET, PLCZ1, PTEN, RAC1, RPS6KB1, STAT5A
cytosol 10 CTNNB1, MAP2K2, MCL1, NGF, PIK3R6, PLCZ1, PTEN, RAC1, RPS6KB1, STAT5A
dendrite 4 MARK2, NGF, NTRK1, RAC1
nuclear body 1 MET
trans-Golgi network 1 RAC1
centrosome 1 CTNNB1
nucleoplasm 8 CTNNB1, MARK2, MCL1, MET, PLCZ1, PTEN, RPS6KB1, STAT5A
RNA polymerase II transcription regulator complex 1 STAT5A
Cell membrane 7 CTLA4, CTNNB1, ITGAM, KIT, NTRK1, PIK3R6, RAC1
Lipid-anchor 1 RAC1
Cytoplasmic side 1 RAC1
lamellipodium 2 CTNNB1, RAC1
ruffle membrane 1 RAC1
Early endosome membrane 1 NTRK1
Synapse 2 CTNNB1, RAC1
cell cortex 2 CTNNB1, RAC1
cell junction 1 CTNNB1
cell surface 4 ITGAM, MET, NTRK1, RPS6KB1
glutamatergic synapse 3 CTNNB1, RAC1, RPS6KB1
Golgi apparatus 2 CTLA4, MAP2K2
Golgi membrane 1 INS
neuronal cell body 1 NTRK1
postsynapse 3 MET, RAC1, RPS6KB1
presynaptic membrane 1 CTNNB1
synaptic vesicle 1 NGF
acrosomal vesicle 1 KIT
plasma membrane 11 CTLA4, CTNNB1, ERBB3, ITGAM, KIT, MARK2, MET, NTRK1, PIK3R6, PTEN, RAC1
Membrane 11 CTNNB1, ERBB3, ITGAM, KIT, MAP2K2, MARK2, MCL1, MET, NTRK1, PIK3R6, RAC1
apical plasma membrane 2 ERBB3, PTEN
axon 2 NGF, NTRK1
basolateral plasma membrane 2 CTNNB1, ERBB3
extracellular exosome 3 CTNNB1, ITGAM, RAC1
endoplasmic reticulum 1 MAP2K2
extracellular space 7 ERBB3, FGF2, IGF1, INS, ITGAM, KIT, NGF
perinuclear region of cytoplasm 5 CTLA4, CTNNB1, MAP2K2, PLCZ1, RPS6KB1
Schaffer collateral - CA1 synapse 1 CTNNB1
adherens junction 1 CTNNB1
apicolateral plasma membrane 1 CTNNB1
bicellular tight junction 1 CTNNB1
mitochondrion 5 MAP2K2, MARK2, MCL1, NTRK1, RPS6KB1
protein-containing complex 2 CTNNB1, NTRK1
postsynaptic density 1 PTEN
pronucleus 1 PLCZ1
Single-pass type I membrane protein 5 CTLA4, ERBB3, ITGAM, KIT, NTRK1
Secreted 5 FGF2, IGF1, INS, NGF, RAC1
extracellular region 8 FGF2, IGF1, INS, MAP2K2, MET, NGF, PTEN, RAC1
cytoplasmic side of plasma membrane 3 KIT, MAP2K2, PTEN
Single-pass membrane protein 2 MCL1, MET
mitochondrial outer membrane 2 MCL1, RPS6KB1
transcription regulator complex 1 CTNNB1
Bcl-2 family protein complex 1 MCL1
external side of plasma membrane 3 CTLA4, ITGAM, KIT
dendritic spine 2 PTEN, RAC1
Z disc 1 CTNNB1
beta-catenin destruction complex 1 CTNNB1
cytoplasmic vesicle 1 RAC1
nucleolus 1 PLCZ1
Wnt signalosome 1 CTNNB1
Early endosome 2 MAP2K2, NTRK1
apical part of cell 1 CTNNB1
cell-cell junction 3 CTNNB1, KIT, MAP2K2
postsynaptic membrane 1 CTNNB1
Cell projection, lamellipodium 1 RAC1
Cytoplasm, perinuclear region 1 PLCZ1
Membrane raft 1 ITGAM
Cytoplasm, cytoskeleton 1 CTNNB1
focal adhesion 3 CTNNB1, MAP2K2, RAC1
microtubule 1 MAP2K2
Cell junction, adherens junction 1 CTNNB1
flotillin complex 1 CTNNB1
peroxisomal membrane 1 MAP2K2
Cell projection, dendritic spine 1 PTEN
Nucleus, PML body 1 PTEN
PML body 1 PTEN
fascia adherens 1 CTNNB1
lateral plasma membrane 3 CTNNB1, ERBB3, MARK2
Late endosome 2 MAP2K2, NTRK1
receptor complex 4 ERBB3, KIT, MET, NTRK1
Cell projection, neuron projection 1 PTEN
neuron projection 2 PTEN, RPS6KB1
chromatin 1 STAT5A
Late endosome membrane 1 NTRK1
cell projection 1 PTEN
cell periphery 1 CTNNB1
cytoskeleton 1 RAC1
Cytoplasm, cytoskeleton, cilium basal body 1 CTNNB1
cytoplasmic ribonucleoprotein granule 1 RAC1
spindle pole 1 CTNNB1
actin filament 1 MARK2
postsynaptic density, intracellular component 1 CTNNB1
microvillus membrane 1 CTNNB1
fibrillar center 1 KIT
Recycling endosome membrane 2 NTRK1, RAC1
Endomembrane system 1 CTNNB1
endosome lumen 2 INS, NGF
myosin complex 1 MCL1
Nucleus, nucleoplasm 1 MCL1
Cell projection, dendrite 2 MARK2, RAC1
specific granule membrane 1 ITGAM
tertiary granule membrane 1 ITGAM
Melanosome 1 RAC1
euchromatin 1 CTNNB1
basal plasma membrane 2 ERBB3, MET
[Isoform 3]: Cytoplasm 1 KIT
exocytic vesicle 1 IGF1
plasma membrane raft 1 ITGAM
secretory granule lumen 1 INS
secretory granule membrane 1 RAC1
Golgi lumen 2 INS, NGF
endoplasmic reticulum lumen 1 INS
platelet alpha granule lumen 1 IGF1
phosphatidylinositol 3-kinase complex 1 PIK3R6
phosphatidylinositol 3-kinase complex, class IA 1 PIK3R6
transport vesicle 1 INS
Schmidt-Lanterman incisure 1 PTEN
beta-catenin-TCF complex 1 CTNNB1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle 1 CTLA4
presynaptic active zone cytoplasmic component 1 CTNNB1
Synapse, synaptosome 1 RPS6KB1
protein-DNA complex 1 CTNNB1
ficolin-1-rich granule membrane 1 RAC1
[Isoform 1]: Cell membrane 1 ERBB3
catenin complex 1 CTNNB1
integrin complex 1 ITGAM
sperm head 1 PLCZ1
ERBB3:ERBB2 complex 1 ERBB3
NADPH oxidase complex 1 RAC1
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
integrin alphaM-beta2 complex 1 ITGAM
myelin sheath adaxonal region 1 PTEN
protein complex involved in cell adhesion 1 CTLA4
[Isoform alpha]: Secreted 1 PTEN
beta-catenin-TCF7L2 complex 1 CTNNB1
beta-catenin-ICAT complex 1 CTNNB1
Scrib-APC-beta-catenin complex 1 CTNNB1
phosphatidylinositol 3-kinase complex, class IB 1 PIK3R6
microtubule bundle 1 MARK2


文献列表

  • S I Othman, M N Bin-Jumah, R S Suliman, S S Althobaiti, E A Alqhtani, S A Gabr. Gingerol fractions bioactivity against butanone cytotoxicity induced in newborns of mice. European review for medical and pharmacological sciences. 2022 09; 26(18):6512-6522. doi: 10.26355/eurrev_202209_29750. [PMID: 36196700]
  • Shoko Kure, Sera Satoi, Toshihiko Kitayama, Yuta Nagase, Nobuo Nakano, Marina Yamada, Noboru Uchiyama, Satoshi Miyashita, Shinya Iida, Hiroyuki Takei, Masao Miyashita. A prediction model using 2-propanol and 2-butanone in urine distinguishes breast cancer. Scientific reports. 2021 10; 11(1):19801. doi: 10.1038/s41598-021-99396-5. [PMID: 34611278]
  • Ayse Sena Mutlu, Shihong Max Gao, Haining Zhang, Meng C Wang. Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans. Nature communications. 2020 03; 11(1):1450. doi: 10.1038/s41467-020-15296-8. [PMID: 32193370]
  • Dian Huang, Chen Yu, Zongze Shao, Minmin Cai, Guangyu Li, Longyu Zheng, Ziniu Yu, Jibin Zhang. Identification and Characterization of Nematicidal Volatile Organic Compounds from Deep-Sea Virgibacillus dokdonensis MCCC 1A00493. Molecules (Basel, Switzerland). 2020 02; 25(3):. doi: 10.3390/molecules25030744. [PMID: 32050419]
  • M P Zhang, Z G Yu, Y X Sun, C J Wang, Z Liu, H Y Wei, W Zou. [Determination of methyl ethyl ketone in urine by headspace gas chromatography]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. 2019 Jun; 37(6):457-459. doi: 10.3760/cma.j.issn.1001-9391.2019.06.013. [PMID: 31256531]
  • Frédéric Cosnier, Hervé Nunge, Élodie Bonfanti, Stéphane Grossmann, Anne-Marie Lambert-Xollin, Samuel Muller, Sylvie Sébillaud, Aurélie Thomas, Laurent Gaté, Pierre Campo. Toluene and methylethylketone: effect of combined exposure on their metabolism in rat. Xenobiotica; the fate of foreign compounds in biological systems. 2018 Jul; 48(7):684-694. doi: 10.1080/00498254.2017.1362604. [PMID: 28783416]
  • Frédéric Cosnier, Stéphane Grossmann, Hervé Nunge, Céline Brochard, Samuel Muller, Anne-Marie Lambert-Xolin, Sylvie Sebillaud, Benoît Rieger, Aurélie Thomas, Marie-Josèphe Décret, Manuella Burgart, Laurent Gaté, Benoît Cossec, Pierre Campo. Metabolism of inhaled methylethylketone in rats. Drug and chemical toxicology. 2018 Jan; 41(1):42-50. doi: 10.1080/01480545.2017.1289220. [PMID: 28633598]
  • Linli Wang, Yuehua Chen, Chunyan Guan, Zhiju Zhao, Qiang Li, Jianguo Yang, Jian Mo, Bin Wang, Wei Wu, Xiaohui Yang, Libing Song, Jun Li. Using low-risk factors to generate non-integrated human induced pluripotent stem cells from urine-derived cells. Stem cell research & therapy. 2017 Nov; 8(1):245. doi: 10.1186/s13287-017-0698-8. [PMID: 29096702]
  • Feng Jin, Jose Thaiparambil, Sri Ramya Donepudi, Venkatrao Vantaku, Danthasinghe Waduge Badrajee Piyarathna, Suman Maity, Rashmi Krishnapuram, Vasanta Putluri, Franklin Gu, Preeti Purwaha, Salil Kumar Bhowmik, Chandrashekar R Ambati, Friedrich-Carl von Rundstedt, Florian Roghmann, Sebastian Berg, Joachim Noldus, Kimal Rajapakshe, Daniel Gödde, Stephan Roth, Stephan Störkel, Stephan Degener, George Michailidis, Benny Abraham Kaipparettu, Balasubramanyam Karanam, Martha K Terris, Shyam M Kavuri, Seth P Lerner, Farrah Kheradmand, Cristian Coarfa, Arun Sreekumar, Yair Lotan, Randa El-Zein, Nagireddy Putluri. Tobacco-Specific Carcinogens Induce Hypermethylation, DNA Adducts, and DNA Damage in Bladder Cancer. Cancer prevention research (Philadelphia, Pa.). 2017 Oct; 10(10):588-597. doi: 10.1158/1940-6207.capr-17-0198. [PMID: 28851690]
  • S Ashokkumar, Aprana S Nair, V Saravanan, M Rajasimman, N Rajamohan. Kinetics studies on the removal of Methyl ethyl ketone using cornstack based biofilter. Ecotoxicology and environmental safety. 2016 Dec; 134(Pt 2):377-382. doi: 10.1016/j.ecoenv.2015.09.016. [PMID: 26409650]
  • Jitendra Kumar Sharma, Pratibha Srivastava, Sadia Ameen, M Shaheer Akhtar, Gurdip Singh, Sudha Yadava. Azadirachta indica plant-assisted green synthesis of Mn3O4 nanoparticles: Excellent thermal catalytic performance and chemical sensing behavior. Journal of colloid and interface science. 2016 Jun; 472(?):220-8. doi: 10.1016/j.jcis.2016.03.052. [PMID: 27038784]
  • Tiago Monteiro, Patrícia R Rodrigues, Ana Luisa Gonçalves, José J G Moura, Elena Jubete, Larraitz Añorga, Barbora Piknova, Alan N Schechter, Célia M Silveira, M Gabriela Almeida. Construction of effective disposable biosensors for point of care testing of nitrite. Talanta. 2015 Sep; 142(?):246-51. doi: 10.1016/j.talanta.2015.04.057. [PMID: 26003719]
  • Chrystelle Le Danvic, Olivier Gérard, Eli Sellem, Claire Ponsart, Philippe Chemineau, Patrice Humblot, Patricia Nagnan-Le Meillour. Enhancing bull sexual behavior using estrus-specific molecules identified in cow urine. Theriogenology. 2015 Jun; 83(9):1381-8. doi: 10.1016/j.theriogenology.2015.02.004. [PMID: 25817331]
  • Zhiliang Wei, Jian Yang, Youhe Chen, Yanqin Lin, Zhong Chen. Line broadening interference for high-resolution nuclear magnetic resonance spectra under inhomogeneous magnetic fields. The Journal of chemical physics. 2015 Apr; 142(13):134202. doi: 10.1063/1.4916520. [PMID: 25854236]
  • Gerhard Lang, Aline Vuarnoz. Matrix-bound 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in tobacco: quantification and evidence for an origin from lignin-incorporated alkaloids. Journal of natural products. 2015 Jan; 78(1):85-92. doi: 10.1021/np500725a. [PMID: 25537002]
  • Marco Ragazzi, Paolo Tosi, Elena Cristina Rada, Vincenzo Torretta, Marco Schiavon. Effluents from MBT plants: plasma techniques for the treatment of VOCs. Waste management (New York, N.Y.). 2014 Nov; 34(11):2400-6. doi: 10.1016/j.wasman.2014.07.026. [PMID: 25168185]
  • Isabel Márquez-Sillero, Soledad Cárdenas, Stefanie Sielemann, Miguel Valcárcel. On-line headspace-multicapillary column-ion mobility spectrometry hyphenation as a tool for the determination of off-flavours in foods. Journal of chromatography. A. 2014 Mar; 1333(?):99-105. doi: 10.1016/j.chroma.2014.01.062. [PMID: 24529959]
  • Catherine Tomicic, David Vernez. Sex differences in urinary levels of several biological indicators of exposure: a simulation study using a compartmental-based toxicokinetic model. Journal of occupational and environmental hygiene. 2014; 11(6):377-87. doi: 10.1080/15459624.2013.875180. [PMID: 24372376]
  • Bo-Yu Zhou, Wang Liu, Bo-Guang Wang, Mi Zhou, Qing Huang, Lei Zhou. [Source profile of volatile carbonyl compounds in wastewater treatment plant of an oil refinery]. Huan jing ke xue= Huanjing kexue. 2013 Jul; 34(7):2560-4. doi: ". [PMID: 24027983]
  • Beatrice Vitali, Maurice Ndagijimana, Simone Maccaferri, Elena Biagi, Maria Elisabetta Guerzoni, Patrizia Brigidi. An in vitro evaluation of the effect of probiotics and prebiotics on the metabolic profile of human microbiota. Anaerobe. 2012 Aug; 18(4):386-91. doi: 10.1016/j.anaerobe.2012.04.014. [PMID: 22579985]
  • M Overland, A Skrede. Fatty acid composition, oxidative stability and sensory quality of meat from broiler chicken fed autolysate from bacteria grown on natural gas. Journal of animal physiology and animal nutrition. 2012 Aug; 96(4):739-46. doi: 10.1111/j.1439-0396.2011.01202.x. [PMID: 21831229]
  • Paweł Mochalski, Agapios Agapiou, Milt Statheropoulos, Anton Amann. Permeation profiles of potential urine-borne biomarkers of human presence over brick and concrete. The Analyst. 2012 Jul; 137(14):3278-85. doi: 10.1039/c2an35214a. [PMID: 22662321]
  • Paula Marie L Ward. Brown and black grease suitability for incorporation into feeds and suitability for biofuels. Journal of food protection. 2012 Apr; 75(4):731-7. doi: 10.4315/0362-028x.jfp-11-221. [PMID: 22488062]
  • Jian Zhang, Wen-Xue Zhang, Jian Yang, Yue-Hong Liu, Xia Zhong, Zheng-Yun Wu, Kenji Kida, Yu Deng. Pretreatment of rice straw using a butanone or an acetaldehyde dilute solution explosion for producing ethanol. Applied biochemistry and biotechnology. 2012 Apr; 166(7):1856-70. doi: 10.1007/s12010-012-9604-0. [PMID: 22371064]
  • Yosuke Hanai, Ken Shimono, Hiroaki Oka, Yoshinobu Baba, Kunio Yamazaki, Gary K Beauchamp. Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice. Cancer cell international. 2012 Feb; 12(1):7. doi: 10.1186/1475-2867-12-7. [PMID: 22364569]
  • Jianjun Li, Guangyun Ye, Duanfang Sun, Taicheng An, Guoping Sun, Shizhong Liang. Performance of a biotrickling filter in the removal of waste gases containing low concentrations of mixed VOCs from a paint and coating plant. Biodegradation. 2012 Feb; 23(1):177-87. doi: 10.1007/s10532-011-9497-6. [PMID: 21809020]
  • Bluma Linkowski Faintuch, Erica A Oliveira, Eutimio G F Nunez, Ana M Moro, P K Nanda, Charles J Smith. Comparison of two peptide radiotracers for prostate carcinoma targeting. Clinics (Sao Paulo, Brazil). 2012; 67(2):163-70. doi: 10.6061/clinics/2012(02)12. [PMID: 22358242]
  • Imed Gargouri, Moncef Khadhraoui, Catherine Nisse, Ariane Leroyer, Mohamed Larbi Masmoudi, Boubaker Elleuch, Denis Zmirou-Navier. Occupational assessment of exposure to organic solvents in an adhesive producing company in Sfax, Tunisia. Journal of occupational and environmental hygiene. 2012; 9(4):D71-6. doi: 10.1080/15459624.2012.666494. [PMID: 22469150]
  • Adriano Costa De Camargo, Thais Maria Ferreira de Souza Vieira, Marisa Aparecida Bismara Regitano-D'Arce, Severino Matias De Alencar, Maria Antonia Calori-Domingues, Solange Guidolin Canniatti-Brazaca. Gamma radiation induced oxidation and tocopherols decrease in in-shell, peeled and blanched peanuts. International journal of molecular sciences. 2012; 13(3):2827-2845. doi: 10.3390/ijms13032827. [PMID: 22489128]
  • Margarita Delgado-Rodríguez, Mercedes Ruiz-Montoya, Inmaculada Giraldez, Rafael López, Engracia Madejón, Manuel Jesús Díaz. Influence of control parameters in VOCs evolution during MSW trimming residues composting. Journal of agricultural and food chemistry. 2011 Dec; 59(24):13035-42. doi: 10.1021/jf2036017. [PMID: 22060272]
  • Mi Zhou, Bo-Guang Wang, De-Jun Zhao, Chun-Lin Zhang, Yin-Gang Gu. [Source emission characteristics of malodorous volatile organic carbonyls from a municipal sewage treatment plant]. Huan jing ke xue= Huanjing kexue. 2011 Dec; 32(12):3571-6. doi: ". [PMID: 22468520]
  • Imed Gargouri, Moncef Khadhraoui, Catherine Nisse, Ariane Leroyer, Mohamed L Masmoudi, Paul Frimat, Daniel Marzin, Boubaker Elleuch, Denis Zmirou-Navier. A case study on co-exposure to a mixture of organic solvents in a Tunisian adhesive-producing company. Journal of occupational medicine and toxicology (London, England). 2011 Nov; 6(?):28. doi: 10.1186/1745-6673-6-28. [PMID: 22082240]
  • Mohammad Dadashipour, Mizue Yamazaki, Kazumi Momonoi, Ken'ichirou Tamura, Ken-Ichi Fuhshuku, Yurina Kanase, Etsuzoh Uchimura, Guan Kaiyun, Yasuhisa Asano. S-selective hydroxynitrile lyase from a plant Baliospermum montanum: molecular characterization of recombinant enzyme. Journal of biotechnology. 2011 May; 153(3-4):100-10. doi: 10.1016/j.jbiotec.2011.02.004. [PMID: 21352863]
  • Catherine Tomicic, Michèle Berode, Anne Oppliger, Vincent Castella, Fabienne Leyvraz, Sophie-Maria Praz-Christinaz, Brigitta Danuser. Sex differences in urinary levels of several biological indicators of exposure: a human volunteer study. Toxicology letters. 2011 May; 202(3):218-25. doi: 10.1016/j.toxlet.2011.01.032. [PMID: 21352904]
  • Emma Dixon, Cynthia Clubb, Sara Pittman, Larry Ammann, Zeehasham Rasheed, Nazia Kazmi, Ali Keshavarzian, Pat Gillevet, Huzefa Rangwala, Robin D Couch. Solid-phase microextraction and the human fecal VOC metabolome. PloS one. 2011 Apr; 6(4):e18471. doi: 10.1371/journal.pone.0018471. [PMID: 21494609]
  • Alicia Olivares, Kseniya Dryahina, José Luis Navarro, David Smith, Patrik Spanĕl, Mónica Flores. SPME-GC-MS versus Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) analyses for the study of volatile compound generation and oxidation status during dry fermented sausage processing. Journal of agricultural and food chemistry. 2011 Mar; 59(5):1931-8. doi: 10.1021/jf104281a. [PMID: 21294565]
  • Poonam Yadav, Nalini V Purohit. Synthesis and biological evaluation of some novel 3,4-disubstituted isocoumarins. Indian journal of pharmaceutical sciences. 2011 Mar; 73(2):171-8. doi: 10.4103/0250-474x.91586. [PMID: 22303060]
  • Pierre-Henri Villard, Fabrice Barlesi, Martine Armand, Thi-Mai-Anh Dao, Jean-Marc Pascussi, Francis Fouchier, Serge Champion, Claire Dufour, Christian Giniès, Ayman Khalil, Marie-Josephe Amiot, Yves Barra, Eric Seree. CYP1A1 induction in the colon by serum: involvement of the PPARα pathway and evidence for a new specific human PPREα site. PloS one. 2011 Jan; 6(1):e14629. doi: 10.1371/journal.pone.0014629. [PMID: 21304969]
  • Jiun H Tsai, Yao S Huang, Zhu X Shieh, Hung L Chiang. Concentration characteristics of VOCs and acids/bases in the gas phase and water-soluble ions in the particle phase at an electrical industry park during construction and mass production. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering. 2011; 46(5):540-51. doi: 10.1080/10934529.2011.551747. [PMID: 21469015]
  • Nobumasa Hara, Kazuo Yamada, Tomoko Shibata, Harumi Osago, Mikako Tsuchiya. Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. PloS one. 2011; 6(8):e22781. doi: 10.1371/journal.pone.0022781. [PMID: 21826208]
  • Toshio Kawai, Kimiaki Sumino, Fumiko Ohashi, Masayuki Ikeda. Use of a holder-vacuum tube device to save on-site hands in preparing urine samples for head-space gas-chromatography, and its application to determine the time allowance for sample sealing. Industrial health. 2011; 49(1):24-9. doi: 10.2486/indhealth.ms1157. [PMID: 20823637]
  • Eun Gyung Lee, James Slaven, Russell B Bowen, Martin Harper. Evaluation of the COSHH Essentials model with a mixture of organic chemicals at a medium-sized paint producer. The Annals of occupational hygiene. 2011 Jan; 55(1):16-29. doi: 10.1093/annhyg/meq067. [PMID: 21047985]
  • Xavier Font, Adriana Artola, Antoni Sánchez. Detection, composition and treatment of volatile organic compounds from waste treatment plants. Sensors (Basel, Switzerland). 2011; 11(4):4043-59. doi: 10.3390/s110404043. [PMID: 22163835]
  • Joanna Rudnicka, Paweł Mochalski, Agapios Agapiou, Milt Statheropoulos, Anton Amann, Bogusław Buszewski. Application of ion mobility spectrometry for the detection of human urine. Analytical and bioanalytical chemistry. 2010 Nov; 398(5):2031-8. doi: 10.1007/s00216-010-4147-0. [PMID: 20820995]
  • Lei Zhang, Lei Nie. Discrimination of geographical origin and adulteration of radix astragali using fourier transform infrared spectroscopy and chemometric methods. Phytochemical analysis : PCA. 2010 Nov; 21(6):609-15. doi: 10.1002/pca.1242. [PMID: 20602337]
  • Hefa Cheng. Volatile flavor compounds in yogurt: a review. Critical reviews in food science and nutrition. 2010 Nov; 50(10):938-50. doi: 10.1080/10408390903044081. [PMID: 21108074]
  • Akira Tani, Seita Tobe, Sachie Shimizu. Uptake of methacrolein and methyl vinyl ketone by tree saplings and implications for forest atmosphere. Environmental science & technology. 2010 Sep; 44(18):7096-101. doi: 10.1021/es1017569. [PMID: 20715865]
  • Zaida Urbán-Morlán, Adriana Ganem-Rondero, Luz María Melgoza-Contreras, José Juan Escobar-Chávez, María Guadalupe Nava-Arzaluz, David Quintanar-Guerrero. Preparation and characterization of solid lipid nanoparticles containing cyclosporine by the emulsification-diffusion method. International journal of nanomedicine. 2010 Sep; 5(?):611-20. doi: 10.2147/ijn.s12125. [PMID: 20856836]
  • Anjali Priyadarshani, Krishna Chuttani, Gaurav Mittal, Aseem Bhatnagar. Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats. Journal of ovarian research. 2010 Apr; 3(?):10. doi: 10.1186/1757-2215-3-10. [PMID: 20420718]
  • Aysel Oztunç, Armağan Onal, Sidika Ertürk Toker. Detection of methamphetamine, methylenedioxymethamphetamine, and 3,4-methylenedioxy-N-ethylamphetamine in spiked plasma by HPLC and TLC. Journal of AOAC International. 2010 Mar; 93(2):556-61. doi: 10.1093/jaoac/93.2.556. [PMID: 20480903]
  • Beatrice Vitali, Maurice Ndagijimana, Federica Cruciani, Paola Carnevali, Marco Candela, Maria Elisabetta Guerzoni, Patrizia Brigidi. Impact of a synbiotic food on the gut microbial ecology and metabolic profiles. BMC microbiology. 2010 Jan; 10(?):4. doi: 10.1186/1471-2180-10-4. [PMID: 20055983]
  • Wan-Suk Oh, Pan-Young Jeong, Hyoe-Jin Joo, Jeong-Eui Lee, Yil-Seong Moon, Hyang-Mi Cheon, Jung-Ho Kim, Yong-Uk Lee, Yhong-Hee Shim, Young-Ki Paik. Identification and characterization of a dual-acting antinematodal agent against the pinewood nematode, Bursaphelenchus xylophilus. PloS one. 2009 Nov; 4(11):e7593. doi: 10.1371/journal.pone.0007593. [PMID: 19907651]
  • Vivek K Bajpai, Sharif M Al-Reza, Ung Kyu Choi, Jong Hwi Lee, Sun Chul Kang. Chemical composition, antibacterial and antioxidant activities of leaf essential oil and extracts of Metasequioa glyptostroboides Miki ex Hu. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2009 Aug; 47(8):1876-83. doi: 10.1016/j.fct.2009.04.043. [PMID: 19426779]
  • Kamil Godula, Marissa L Umbel, David Rabuka, Zsofia Botyanszki, Carolyn R Bertozzi, Raghuveer Parthasarathy. Control of the molecular orientation of membrane-anchored biomimetic glycopolymers. Journal of the American Chemical Society. 2009 Jul; 131(29):10263-8. doi: 10.1021/ja903114g. [PMID: 19580278]
  • Antônio Felipe F Oliveira, Patrícia P Maia, Maria José N Paiva, Maria Elisa P B Siqueira. Determination of 2,5-hexanedione in urine by headspace solid-phase microextraction and gas chromatography. Journal of analytical toxicology. 2009 May; 33(4):223-8. doi: 10.1093/jat/33.4.223. [PMID: 19470226]
  • Andriy Pysanenko, Tianshu Wang, Patrik Spanel, David Smith. Acetone, butanone, pentanone, hexanone and heptanone in the headspace of aqueous solution and urine studied by selected ion flow tube mass spectrometry. Rapid communications in mass spectrometry : RCM. 2009 Apr; 23(8):1097-104. doi: 10.1002/rcm.3963. [PMID: 19280607]
  • Rajshekar Chimkode, M B Patil, Sunil Jalalpure, T Y Pasha, Sibaji Sarkar. A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats. Ancient science of life. 2009 Apr; 28(4):32-5. doi: ". [PMID: 22557330]
  • Ven-Shing Wang, Ming-Yen Lu. Application of solid-phase microextraction and gas chromatography-mass spectrometry for measuring chemicals in saliva of synthetic leather workers. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2009 Jan; 877(1-2):24-32. doi: 10.1016/j.jchromb.2008.11.006. [PMID: 19036646]
  • Marcello Civilini. Identification and characterization of bacteria isolated under selective pressure of volatile organic compounds. Journal of environmental biology. 2009 Jan; 30(1):99-105. doi: ". [PMID: 20112870]
  • S Smith, H Burden, R Persad, K Whittington, B de Lacy Costello, N M Ratcliffe, C S Probert. A comparative study of the analysis of human urine headspace using gas chromatography-mass spectrometry. Journal of breath research. 2008 Sep; 2(3):037022. doi: 10.1088/1752-7155/2/3/037022. [PMID: 21386182]
  • Chitsan Lin, Naiwei Liou, Endy Sun. Applications of open-path Fourier transform infrared for identification of volatile organic compound pollution sources and characterization of source emission behaviors. Journal of the Air & Waste Management Association (1995). 2008 Jun; 58(6):821-8. doi: 10.3155/1047-3289.58.6.821. [PMID: 18581812]
  • Michiel van Wijk, Paulien J A De Bruijn, Maurice W Sabelis. Predatory mite attraction to herbivore-induced plant odors is not a consequence of attraction to individual herbivore-induced plant volatiles. Journal of chemical ecology. 2008 Jun; 34(6):791-803. doi: 10.1007/s10886-008-9492-5. [PMID: 18521678]
  • Charlotte M Andersen, Lene T Andersen, Anne Mette Hansen, Leif H Skibsted, Mikael A Petersen. Wavelength dependence of light-induced lipid oxidation and naturally occurring photosensitizers in cheese. Journal of agricultural and food chemistry. 2008 Mar; 56(5):1611-8. doi: 10.1021/jf072672f. [PMID: 18275145]
  • B S Patton, E Huff-Lonergan, M S Honeyman, J D Crouse, B J Kerr, S M Lonergan. Effects of deep-bedded finishing system on market pig performance, composition and pork quality. Animal : an international journal of animal bioscience. 2008 Mar; 2(3):459-70. doi: 10.1017/s1751731107001292. [PMID: 22445049]
  • B Davison, A Brunner, C Ammann, C Spirig, M Jocher, A Neftel. Cut-induced VOC emissions from agricultural grasslands. Plant biology (Stuttgart, Germany). 2008 Jan; 10(1):76-85. doi: 10.1055/s-2007-965043. [PMID: 17538867]
  • Hirohiko Ukai, Toshio Kawai, Osamu Inoue, Yuki Maejima, Yoshinari Fukui, Fumiko Ohashi, Satoru Okamoto, Shiro Takada, Haruhiko Sakurai, Masayuki Ikeda. Comparative evaluation of biomarkers of occupational exposure to toluene. International archives of occupational and environmental health. 2007 Oct; 81(1):81-93. doi: 10.1007/s00420-007-0193-0. [PMID: 17653568]
  • Catherine E Garner, Stephen Smith, Ben de Lacy Costello, Paul White, Robert Spencer, Chris S J Probert, Norman M Ratcliffe. Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2007 Jun; 21(8):1675-88. doi: 10.1096/fj.06-6927com. [PMID: 17314143]
  • Nanzad Tsevegsuren, RuAngelie Edrada, Wenhan Lin, Rainer Ebel, Claudia Torre, Sofia Ortlepp, Victor Wray, Peter Proksch. Biologically active natural products from Mongolian medicinal plants Scorzonera divaricata and Scorzonera pseudodivaricata. Journal of natural products. 2007 Jun; 70(6):962-7. doi: 10.1021/np070013r. [PMID: 17542634]
  • Luciano J Costa, Robert M Gemmill, Harry A Drabkin. Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells. Urology. 2007 Mar; 69(3):596-602. doi: 10.1016/j.urology.2007.01.053. [PMID: 17382186]
  • Adrian Fuente, Bradley McPherson. Central auditory processing effects induced by solvent exposure. International journal of occupational medicine and environmental health. 2007; 20(3):271-9. doi: 10.2478/v10001-007-0030-4. [PMID: 17932017]
  • Y Andres, E Dumont, P Le Cloirec, E Ramirez-Lopez. Wood bark as packing material in a biofilter used for air treatment. Environmental technology. 2006 Dec; 27(12):1297-301. doi: 10.1080/09593332708618747. [PMID: 17285934]
  • Richard W Clapp. Mortality among US employees of a large computer manufacturing company: 1969-2001. Environmental health : a global access science source. 2006 Oct; 5(?):30. doi: 10.1186/1476-069x-5-30. [PMID: 17052328]
  • A M Saillenfait, F Gallissot, J P Sabaté, N Bourges-Abella, R Cadot, G Morel, A M Lambert. Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2006 Aug; 44(8):1287-98. doi: 10.1016/j.fct.2006.02.006. [PMID: 16624470]
  • Marcello Civilini. Multiple microbial activities for volatile organic compounds reduction by biofiltration. Journal of the Air & Waste Management Association (1995). 2006 Jul; 56(7):922-30. doi: 10.1080/10473289.2006.10464503. [PMID: 16878585]
  • S A Filichkin, R Meilan, V B Busov, C Ma, A M Brunner, S H Strauss. Alcohol-inducible gene expression in transgenic Populus. Plant cell reports. 2006 Jul; 25(7):660-7. doi: 10.1007/s00299-005-0112-3. [PMID: 16496153]
  • Pamela R D Williams, Jacqueline Patterson, Daniel W Briggs. VCCEP pilot: progress on evaluating children's risks and data needs. Risk analysis : an official publication of the Society for Risk Analysis. 2006 Jun; 26(3):781-801. doi: 10.1111/j.1539-6924.2006.00766.x. [PMID: 16834634]
  • Ania Mendoza-Cantú, Fabiola Castorena-Torres, Mario Bermúdez de León, Bulmaro Cisneros, Lizbeth López-Carrillo, Aurora E Rojas-García, Alberto Aguilar-Salinas, Maurizio Manno, Arnulfo Albores. Occupational toluene exposure induces cytochrome P450 2E1 mRNA expression in peripheral lymphocytes. Environmental health perspectives. 2006 Apr; 114(4):494-9. doi: 10.1289/ehp.8192. [PMID: 16581535]
  • Bernard Cartigny, Nathalie Azaroual, Christophe Bochu, Elisabeth Vinner, Michel Imbenotte, Gaston Vermeersch, Michel Lhermitte. Analysis of ingested material and urine by GC-MS and 1H NMR spectroscopy: poisoning of an adult with adulterated soda. Journal of analytical toxicology. 2006 Mar; 30(2):86-90. doi: 10.1093/jat/30.2.86. [PMID: 16620537]
  • Helga David, Gerald Hofmann, Ana Paula Oliveira, Hanne Jarmer, Jens Nielsen. Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans. Genome biology. 2006; 7(11):R108. doi: 10.1186/gb-2006-7-11-r108. [PMID: 17107606]
  • Gudrun Olafsdottir, Rosa Jonsdottir, Hélène L Lauzon, Joop Luten, Kristberg Kristbergsson. Characterization of volatile compounds in chilled cod (Gadus morhua) fillets by gas chromatography and detection of quality indicators by an electronic nose. Journal of agricultural and food chemistry. 2005 Dec; 53(26):10140-7. doi: 10.1021/jf0517804. [PMID: 16366707]
  • Paul Catz, Walter Shinn, Izet M Kapetanovic, Hyuntae Kim, Moonsun Kim, Elaine L Jacobson, Myron K Jacobson, Carol E Green. Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Dec; 829(1-2):123-35. doi: 10.1016/j.jchromb.2005.10.003. [PMID: 16275131]
  • Jing-Zhen Deng, Shelley R Starck, Shisheng Li, Sidney M Hecht. (+)-Myristinins A and D from Knema elegans, which inhibit DNA polymerase beta and cleave DNA. Journal of natural products. 2005 Nov; 68(11):1625-8. doi: 10.1021/np058064g. [PMID: 16309311]
  • Mireille Vega, Salwa Karboune, Selim Kermasha. Stability of immobilized soybean lipoxygenase in selected organic solvent media. Applied biochemistry and biotechnology. 2005 Oct; 127(1):29-42. doi: 10.1385/abab:127:1:029. [PMID: 16186621]
  • M Statheropoulos, E Sianos, A Agapiou, A Georgiadou, A Pappa, N Tzamtzis, H Giotaki, C Papageorgiou, D Kolostoumbis. Preliminary investigation of using volatile organic compounds from human expired air, blood and urine for locating entrapped people in earthquakes. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Aug; 822(1-2):112-7. doi: 10.1016/j.jchromb.2005.05.028. [PMID: 15996539]
  • Patrick F Finn, J Fred Dice. Ketone bodies stimulate chaperone-mediated autophagy. The Journal of biological chemistry. 2005 Jul; 280(27):25864-70. doi: 10.1074/jbc.m502456200. [PMID: 15883160]
  • Lilian R F Carvalho, Perola C Vasconcellos, Waldir Mantovani, Cristina S Pool, Silvana O Pisani. Measurements of biogenic hydrocarbons and carbonyl compounds emitted by trees from temperate warm Atlantic rainforest, Brazil. Journal of environmental monitoring : JEM. 2005 May; 7(5):493-9. doi: 10.1039/b414881a. [PMID: 15877172]
  • Ho-Yuan Chang, Yuan-Der Yun, Yi-Chun Yu, Tung-Sheng Shih, Ming-Song Lin, Hsien-Wen Kuo, Kuo-Ming Chen. The effects of simultaneous exposure to methyl ethyl ketone and toluene on urinary biomarkers of occupational N,N-dimethylformamide exposure. Toxicology letters. 2005 Mar; 155(3):385-95. doi: 10.1016/j.toxlet.2004.11.005. [PMID: 15649622]
  • Gisela Skopp, Georg Schmitt, Lucia Pötsch. Plasma-to-blood ratios of congener analytes. Journal of analytical toxicology. 2005 Mar; 29(2):145-7. doi: 10.1093/jat/29.2.145. [PMID: 15902984]
  • Greg Kullman, Randy Boylstein, William Jones, Chris Piacitelli, Stephanie Pendergrass, Kathleen Kreiss. Characterization of respiratory exposures at a microwave popcorn plant with cases of bronchiolitis obliterans. Journal of occupational and environmental hygiene. 2005 Mar; 2(3):169-78. doi: 10.1080/15459620590923091. [PMID: 15764540]
  • M Imbriani, S Ghittori. Gases and organic solvents in urine as biomarkers of occupational exposure: a review. International archives of occupational and environmental health. 2005 Feb; 78(1):1-19. doi: 10.1007/s00420-004-0544-z. [PMID: 15592680]
  • V S Prakash Chaturvedula, Bing-Nan Zhou, Zhijie Gao, Shannon J Thomas, Sidney M Hecht, David G I Kingston. New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta. Bioorganic & medicinal chemistry. 2004 Dec; 12(23):6271-5. doi: 10.1016/j.bmc.2004.08.048. [PMID: 15519169]
  • David J Anick. High sensitivity 1H-NMR spectroscopy of homeopathic remedies made in water. BMC complementary and alternative medicine. 2004 Nov; 4(?):15. doi: 10.1186/1472-6882-4-15. [PMID: 15518588]
  • Xizhi Feng, Zhijie Gao, Shisheng Li, Shannon H Jones, Sidney M Hecht. DNA polymerase beta lyase inhibitors from Maytenus putterlickoides. Journal of natural products. 2004 Oct; 67(10):1744-7. doi: 10.1021/np040057p. [PMID: 15497954]
  • Shi-Sheng Li, Zhijie Gao, Xizhi Feng, Shannon H Jones, Sidney M Hecht. Plant sterols as selective DNA polymerase beta lyase inhibitors and potentiators of bleomycin cytotoxicity. Bioorganic & medicinal chemistry. 2004 Aug; 12(15):4253-8. doi: 10.1016/j.bmc.2004.05.016. [PMID: 15246101]
  • V S Prakash Chaturvedula, Sidney M Hecht, Zhijie Gao, Shannon H Jones, Xizhi Feng, David G I Kingston. New neolignans that inhibit DNA polymerase beta lyase. Journal of natural products. 2004 Jun; 67(6):964-7. doi: 10.1021/np030507y. [PMID: 15217274]
  • Marco Steeghs, Harsh Pal Bais, Joost de Gouw, Paul Goldan, William Kuster, Megan Northway, Ray Fall, Jorge M Vivanco. Proton-transfer-reaction mass spectrometry as a new tool for real time analysis of root-secreted volatile organic compounds in Arabidopsis. Plant physiology. 2004 May; 135(1):47-58. doi: 10.1104/pp.104.038703. [PMID: 15141066]
  • S Albu, E Joyce, L Paniwnyk, J P Lorimer, T J Mason. Potential for the use of ultrasound in the extraction of antioxidants from Rosmarinus officinalis for the food and pharmaceutical industry. Ultrasonics sonochemistry. 2004 May; 11(3-4):261-5. doi: 10.1016/j.ultsonch.2004.01.015. [PMID: 15081992]
  • Stephanie M Pendergrass. Method development for the determination of diacetyl and acetoin at a microwave popcorn plant. Environmental science & technology. 2004 Feb; 38(3):858-61. doi: 10.1021/es0305407. [PMID: 14968874]
  • Hirokazu Hosoyama, Akio Sugimoto, Yuko Suzuki, Iwao Sakane, Takami Kakuda. [Isolation and quantitative analysis of the alpha-amylase inhibitor in Lagerstroemia speciosa (L.) Pers. (Banaba)]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2003 Jul; 123(7):599-605. doi: 10.1248/yakushi.123.599. [PMID: 12875243]