Picoline (BioDeep_00000870255)

代谢物信息卡片

o-Picoline [UN2313] [Flammable liquid]

化学式: C6H7N (93.0578462)
中文名称: 2-甲基吡啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC=CC=N1
InChI: InChI=1S/C6H7N/c1-6-4-2-3-5-7-6/h2-5H,1H3

描述信息

同义名列表

39 个代谢物同义名

o-Picoline [UN2313] [Flammable liquid]; InChI=1\C6H7N\c1-6-4-2-3-5-7-6\h2-5H,1H; 2-Pyridylmethyl radica1; .alpha.-Methylpyridine; RCRA waste number U191; alpha-Methylpyridine; RCRA waste no. U191; Pyridine, 2-methyl-; 2-METHYL-PYRIDINE; 2-METHYLPYRIDINE; .alpha.-Picoline; O-Methylpyridine; EINECS 203-643-7; NCGC00160644-01; PICOLINE, ALPHA; AC-907\34117032; NCIOpen2_007919; NCIOpen2_007826; 109835_ALDRICH; alpha-Picoline; ZINC00967365; WLN: T6NJ B1; 80221_FLUKA; CHEBI:32545; 52962-96-6; 2-picoline; 45505-34-8; O-Picoline; 82005-07-0; CCRIS 1721; AI3-24109; 109-06-8; NSC 3409; HSDB 101; Picoline; AI3-2409; NSC3409; C14447; 2-Mepy

数据库引用编号

6 个数据库交叉引用编号

ChEBI: CHEBI:50415
PubChem: 7975
ChEMBL: CHEMBL15732
CAS: 10259-19-5
CAS: 1333-41-1
CAS: 109-06-8

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

33090 满山红: -
4097 Nicotiana tabacum: 10.1016/S0031-9422(00)82932-5
3885 Phaseolus vulgaris: 10.1021/JF60199A053
4442 Camellia sinensis: 10.1021/JF60201A032
292239 Mentha arvensis: 10.1021/JF00021A034
3619 Rumex obtusifolius: 10.1038/181636A0
4097 Nicotiana tabacum: 10.1016/S0031-9422(00)82932-5
3885 Phaseolus vulgaris: 10.1021/JF60199A053
4442 Camellia sinensis: 10.1021/JF60201A032
292239 Mentha arvensis: 10.1021/JF00021A034
3619 Rumex obtusifolius: 10.1038/181636A0

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Hassen Touzi, Yves Chevalier, Marie Martin, Hafedh Ben Ouada, Nicole Jaffrezic-Renault. Detection of Gadolinium with an Impedimetric Platform Based on Gold Electrodes Functionalized by 2-Methylpyridine-Substituted Cyclam. Sensors (Basel, Switzerland). 2021 Feb; 21(5):. doi: 10.3390/s21051658. [PMID: 33670860]
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Sarah D Brown, Katherine D Trotter, Oliver B Sutcliffe, Jane A Plumb, Bruce Waddell, Naomi E B Briggs, Nial J Wheate. Combining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity. Dalton transactions (Cambridge, England : 2003). 2012 Oct; 41(37):11330-9. doi: 10.1039/c2dt31313h. [PMID: 22886151]
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Rahele Ghanbari, Farooq Anwar, Khalid M Alkharfy, Anwarul-Hassan Gilani, Nazamid Saari. Valuable nutrients and functional bioactives in different parts of olive (Olea europaea L.)-a review. International journal of molecular sciences. 2012; 13(3):3291-3340. doi: 10.3390/ijms13033291. [PMID: 22489153]
Xiangdong Su, Fabienne Pradaux-Caggiano, Nigel Vicker, Mark P Thomas, Heather Halem, Michael D Culler, Barry V L Potter. Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. ChemMedChem. 2011 Sep; 6(9):1616-29. doi: 10.1002/cmdc.201100182. [PMID: 21714097]
Chi-Hui Tang, Christi Parham, Ellyn Shocron, Gerald McMahon, Neela Patel. Picoplatin overcomes resistance to cell toxicity in small-cell lung cancer cells previously treated with cisplatin and carboplatin. Cancer chemotherapy and pharmacology. 2011 Jun; 67(6):1389-400. doi: 10.1007/s00280-010-1435-5. [PMID: 20809122]
Shuanglian Li, Ying Chen, Shuzhong Zhang, Swati S More, Xiaozhu Huang, Kathleen M Giacomini. Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice. Pharmaceutical research. 2011 Mar; 28(3):610-25. doi: 10.1007/s11095-010-0312-6. [PMID: 21104302]
Poonam Yadav, Nalini V Purohit. Synthesis and biological evaluation of some novel 3,4-disubstituted isocoumarins. Indian journal of pharmaceutical sciences. 2011 Mar; 73(2):171-8. doi: 10.4103/0250-474x.91586. [PMID: 22303060]
Sabine H van Rijt, Hana Kostrhunova, Viktor Brabec, Peter J Sadler. Functionalization of osmium arene anticancer complexes with (poly)arginine: effect on cellular uptake, internalization, and cytotoxicity. Bioconjugate chemistry. 2011 Feb; 22(2):218-26. doi: 10.1021/bc100369p. [PMID: 21271713]
L Renee Ruhaak, René Hennig, Carolin Huhn, Matthias Borowiak, Radboud J E M Dolhain, André M Deelder, Erdmann Rapp, Manfred Wuhrer. Optimized workflow for preparation of APTS-labeled N-glycans allowing high-throughput analysis of human plasma glycomes using 48-channel multiplexed CGE-LIF. Journal of proteome research. 2010 Dec; 9(12):6655-64. doi: 10.1021/pr100802f. [PMID: 20886907]
George Sachs, Jai Moo Shin, Richard Hunt. Novel approaches to inhibition of gastric acid secretion. Current gastroenterology reports. 2010 Dec; 12(6):437-47. doi: 10.1007/s11894-010-0149-5. [PMID: 20924727]
Olivier Berdeaux, Stéphane Gregoire, Cindie Fournier, William W Christie, Pierre Lambelet, Jean-Louis Sébédio. Detection of lactobacillic acid in low erucic rapeseed oil--A note of caution when quantifying cyclic fatty acid monomers in vegetable oils. Chemistry and physics of lipids. 2010 Sep; 163(7):698-702. doi: 10.1016/j.chemphyslip.2010.07.002. [PMID: 20654602]
L Renee Ruhaak, Evelyne Steenvoorden, Carolien A M Koeleman, André M Deelder, Manfred Wuhrer. 2-picoline-borane: a non-toxic reducing agent for oligosaccharide labeling by reductive amination. Proteomics. 2010 Jun; 10(12):2330-6. doi: 10.1002/pmic.200900804. [PMID: 20391534]
Abhishek Srivastava, Lu-Yun Lian, James L Maggs, Masautso Chaponda, Munir Pirmohamed, Dominic P Williams, B Kevin Park. Quantifying the metabolic activation of nevirapine in patients by integrated applications of NMR and mass spectrometries. Drug metabolism and disposition: the biological fate of chemicals. 2010 Jan; 38(1):122-32. doi: 10.1124/dmd.109.028688. [PMID: 19797610]
Mario Kallenbach, Ian T Baldwin, Gustavo Bonaventure. A rapid and sensitive method for the simultaneous analysis of aliphatic and polar molecules containing free carboxyl groups in plant extracts by LC-MS/MS. Plant methods. 2009 Nov; 5(?):17. doi: 10.1186/1746-4811-5-17. [PMID: 19939243]
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Kouwa Yamashita, Risa Nakagawa, Mitsunobu Okuyama, Seijiro Honma, Madoka Takahashi, Mitsuteru Numazawa. Simultaneous determination of tetrahydrocortisol, allotetrahydrocortisol and tetrahydrocortisone in human urine by liquid chromatography-electrospray ionization tandem mass spectrometry. Steroids. 2008 Aug; 73(7):727-37. doi: 10.1016/j.steroids.2008.02.009. [PMID: 18394666]
Kouwa Yamashita, Mitsunobu Okuyama, Risa Nakagawa, Seijiro Honma, Fumitoshi Satoh, Ryo Morimoto, Sadayoshi Ito, Madoka Takahashi, Mitsuteru Numazawa. Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids. Journal of chromatography. A. 2008 Jul; 1200(2):114-21. doi: 10.1016/j.chroma.2008.05.034. [PMID: 18561939]
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