Butylphen (BioDeep_00000869543)
代谢物信息卡片
InChI=1\C10H14O\c1-10(2,3)8-4-6-9(11)7-5-8\h4-7,11H,1-3H
化学式: C10H14O (150.1045)
中文名称: 4-叔丁基苯酚, 对叔丁基苯酚(PTBP)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)C1=CC=C(C=C1)O
InChI: InChI=1S/C10H14O/c1-10(2,3)8-4-6-9(11)7-5-8/h4-7,11H,1-3H3
描述信息
同义名列表
35 个代谢物同义名
InChI=1\C10H14O\c1-10(2,3)8-4-6-9(11)7-5-8\h4-7,11H,1-3H; EPA Pesticide Chemical Code 064113; Phenol, 4-(1,1-dimethylethyl)-; 1-Hydroxy-4-tert-butylbenzene; 4-(1,1-Dimethylethyl)phenol; Ucar butylphenol 4-T flake; p-terc.Butylfenol [Czech]; Phenol, p-(tert-butyl)-; Phenol, p-tert-butyl-; Ucar butylphenol 4-T; WLN: QR DX1 & 1 & 1; 4-tert-Butylphenol; p-Tert-butylphenol; 4-(t-Butyl)phenol; p-Terc.butylfenol; p-t-Butyl phenol; EINECS 202-679-0; Caswell No. 130E; NCGC00159377-02; NCGC00159377-03; 4-t-Butylphenol; W391808_ALDRICH; B99901_ALDRICH; 506761_SUPELCO; 425761_ALDRICH; CHEBI:34444; Butylphen; AI3-00126; NSC 3697; NSC3697; 98-54-4; C14200; PTBP; 4-tert-Butylphenol; 4-Tert-butylphenol
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:34444
- PubChem: 7393
- ChEMBL: CHEMBL16217
- CAS: 30813-81-1
- CAS: 98-54-4
- KEGG: C14200
- PubChem: 7847010
- KNApSAcK: 34444
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 33090 - 薄荷: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yongmeng Yang, Chen Yan, Aifeng Li, Jiangbing Qiu, Wenhui Yan, Hui Dang. Effects of the plastic additive 2,4-di-tert-butylphenol on intestinal microbiota of zebrafish.
Journal of hazardous materials.
2024 May; 469(?):133987. doi:
10.1016/j.jhazmat.2024.133987. [PMID: 38461668] - Never Zekeya, Bertha Mamiro, Humphrey Ndossi, Rehema Chande Mallya, Mhuji Kilonzo, Alex Kisingo, Mkumbukwa Mtambo, Jafari Kideghesho, Jaffu Chilongola. Screening and evaluation of cytotoxicity and antiviral effects of secondary metabolites from water extracts of Bersama abyssinica against SARS-CoV-2 Delta.
BMC complementary medicine and therapies.
2022 Oct; 22(1):280. doi:
10.1186/s12906-022-03754-3. [PMID: 36289484] - Younes M Rashad, Sara A Abdalla, Ahmed S Shehata. Aspergillus flavus YRB2 from Thymelaea hirsuta (L.) Endl., a non-aflatoxigenic endophyte with ability to overexpress defense-related genes against Fusarium root rot of maize.
BMC microbiology.
2022 09; 22(1):229. doi:
10.1186/s12866-022-02651-6. [PMID: 36175855] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - A Aziz, P Agamuthu, S H Fauziah. Effective removal of p-tert-Butylphenol and Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)- from landfill leachate using locust bean gum.
Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA.
2018 Dec; 36(12):1146-1156. doi:
10.1177/0734242x18789062. [PMID: 30067147] - Dan A, Daiki Fujii, Satoshi Soda, Takashi Machimura, Michihiko Ike. Removal of phenol, bisphenol A, and 4-tert-butylphenol from synthetic landfill leachate by vertical flow constructed wetlands.
The Science of the total environment.
2017 Feb; 578(?):566-576. doi:
10.1016/j.scitotenv.2016.10.232. [PMID: 27836343] - Kaori Sadakane, Takamichi Ichinose, Hirohisa Takano, Rie Yanagisawa, Eiko Koike, Ken-ichiro Inoue. The alkylphenols 4-nonylphenol, 4-tert-octylphenol and 4-tert-butylphenol aggravate atopic dermatitis-like skin lesions in NC/Nga mice.
Journal of applied toxicology : JAT.
2014 Aug; 34(8):893-902. doi:
10.1002/jat.2911. [PMID: 23983229] - Yuka Ogata, Tadashi Toyama, Ning Yu, Xuan Wang, Kazunari Sei, Michihiko Ike. Occurrence of 4-tert-butylphenol (4-t-BP) biodegradation in an aquatic sample caused by the presence of Spirodela polyrrhiza and isolation of a 4-t-BP-utilizing bacterium.
Biodegradation.
2013 Apr; 24(2):191-202. doi:
10.1007/s10532-012-9570-9. [PMID: 22777343] - Sanka N Atapattu, Jack M Rosenfeld. Solid phase analytical derivatization of anthropogenic and natural phenolic estrogen mimics with pentafluoropyridine for gas chromatography-mass spectrometry.
Journal of chromatography. A.
2011 Dec; 1218(51):9135-41. doi:
10.1016/j.chroma.2011.10.060. [PMID: 22104213] - Juanjuan Feng, Min Sun, Lili Xu, Jubai Li, Xia Liu, Shengxiang Jiang. Preparation of metal wire supported solid-phase microextraction fiber coated with multi-walled carbon nanotubes.
Journal of separation science.
2011 Sep; 34(18):2482-8. doi:
10.1002/jssc.201100375. [PMID: 21739606] - Shabana I Khan, Jianping Zhao, Ikhlas A Khan, Larry A Walker, Asok K Dasmahapatra. Potential utility of natural products as regulators of breast cancer-associated aromatase promoters.
Reproductive biology and endocrinology : RB&E.
2011 Jun; 9(?):91. doi:
10.1186/1477-7827-9-91. [PMID: 21693041] - Esen Ozkaya, Meryem Sevinç Elinç-Aslan, Leyla Mirzoyeva. Allergic contact dermatitis caused by p-tert-butylphenol formaldehyde resin and colophonium in neoprene thermal sauna shorts.
Contact dermatitis.
2010 Oct; 63(4):230-2. doi:
10.1111/j.1600-0536.2010.01807.x. [PMID: 20831691] - Tadashi Toyama, Naonori Momotani, Yuka Ogata, Yuji Miyamori, Daisuke Inoue, Kazunari Sei, Kazuhiro Mori, Shintaro Kikuchi, Michihiko Ike. Isolation and characterization of 4-tert-butylphenol-utilizing Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment.
Applied and environmental microbiology.
2010 Oct; 76(20):6733-40. doi:
10.1128/aem.00258-10. [PMID: 20802076] - Kai K Lie, Sonnich Meier, Pål A Olsvik. Effects of environmental relevant doses of pollutants from offshore oil production on Atlantic cod (Gadus morhua).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2009 Aug; 150(2):141-9. doi:
10.1016/j.cbpc.2009.04.004. [PMID: 19379838] - Hong Sun, Xiao-Lin Xu, Jian-Hua Qu, Xia Hong, Yu-Bang Wang, Li-Chun Xu, Xin-Ru Wang. 4-Alkylphenols and related chemicals show similar effect on the function of human and rat estrogen receptor alpha in reporter gene assay.
Chemosphere.
2008 Mar; 71(3):582-8. doi:
10.1016/j.chemosphere.2007.09.031. [PMID: 18028983] - Eun-Joung Ko, Kyoung-Woong Kim, Seo-Young Kang, Sang-Don Kim, Sun-Baek Bang, Se-Yeong Hamm, Dong-Wook Kim. Monitoring of environmental phenolic endocrine disrupting compounds in treatment effluents and river waters, Korea.
Talanta.
2007 Oct; 73(4):674-83. doi:
10.1016/j.talanta.2007.04.033. [PMID: 19073088] - K-E Tollefsen. Binding of alkylphenols and alkylated non-phenolics to the rainbow trout (Oncorhynchus mykiss) plasma sex steroid-binding protein.
Ecotoxicology and environmental safety.
2007 Sep; 68(1):40-8. doi:
10.1016/j.ecoenv.2006.07.002. [PMID: 16945415] - Knut-Erik Tollefsen, Eivind Farmen Finne, Randi Romstad, Cecilie Sandberg. Effluents from oil production activities contain chemicals that interfere with normal function of intra- and extra-cellular estrogen binding proteins.
Marine environmental research.
2006 Jul; 62 Suppl(?):S191-4. doi:
10.1016/j.marenvres.2006.04.006. [PMID: 16697461] - Migaku Kawaguchi, Norihiro Sakui, Noriya Okanouchi, Rie Ito, Koichi Saito, Shun-ichiro Izumi, Tsunehisa Makino, Hiroyuki Nakazawa. Stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography--mass spectrometry for measurement of phenolic xenoestrogens in human urine samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Jun; 820(1):49-57. doi:
10.1016/j.jchromb.2005.03.019. [PMID: 15866492] - Zsuzsanna Kuklenyik, John Ekong, Caroline D Cutchins, Larry L Needham, Antonia M Calafat. Simultaneous measurement of urinary bisphenol A and alkylphenols by automated solid-phase extractive derivatization gas chromatography/mass spectrometry.
Analytical chemistry.
2003 Dec; 75(24):6820-5. doi:
10.1021/ac0303158. [PMID: 14670041] - Hong Fang, Weida Tong, William S Branham, Carrie L Moland, Stacy L Dial, Huixiao Hong, Qian Xie, Roger Perkins, William Owens, Daniel M Sheehan. Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Chemical research in toxicology.
2003 Oct; 16(10):1338-58. doi:
10.1021/tx030011g. [PMID: 14565775] - Tapio E Haavisto, N Annika Adamsson, Sari A Myllymäki, Jorma Toppari, Jorma Paranko. Effects of 4-tert-octylphenol, 4-tert-butylphenol, and diethylstilbestrol on prenatal testosterone surge in the rat.
Reproductive toxicology (Elmsford, N.Y.).
2003 Sep; 17(5):593-605. doi:
10.1016/s0890-6238(03)00103-5. [PMID: 14555198] - Jian-Ying Hu, Takako Aizawa. Quantitative structure-activity relationships for estrogen receptor binding affinity of phenolic chemicals.
Water research.
2003 Mar; 37(6):1213-22. doi:
10.1016/s0043-1354(02)00378-0. [PMID: 12598185] - F Yang, R Sarangarajan, I C Le Poole, E E Medrano, R E Boissy. The cytotoxicity and apoptosis induced by 4-tertiary butylphenol in human melanocytes are independent of tyrosinase activity.
The Journal of investigative dermatology.
2000 Jan; 114(1):157-64. doi:
10.1046/j.1523-1747.2000.00836.x. [PMID: 10620132] - F Yang, Z Abdel-Malek, R E Boissy. Effects of commonly used mitogens on the cytotoxicity of 4-tertiary butylphenol to human melanocytes.
In vitro cellular & developmental biology. Animal.
1999 Nov; 35(10):566-70. doi:
10.1007/s11626-999-0094-5. [PMID: 10614865] - E Zimerson, M Bruze. Demonstration of the contact sensitizer p-tert-butylcatechol in p-tert-butylphenol formaldehyde resin.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.
1999 Mar; 10(1):2-6. doi:
10.1016/s1046-199x(99)90086-6. [PMID: 10072335] - T Estlander, M Kostiainen, R Jolanki, L Kanerva. Active sensitization and occupational allergic contact dermatitis caused by para-tertiary-butylcatechol.
Contact dermatitis.
1998 Feb; 38(2):96-100. doi:
10.1111/j.1600-0536.1998.tb05659.x. [PMID: 9506222] - J Handley, D Todd, A Bingham, R Corbett, D Burrows. Allergic contact dermatitis from para-tertiary-butylphenol-formaldehyde resin (PTBP-F-R) in Northern Ireland.
Contact dermatitis.
1993 Sep; 29(3):144-6. doi:
10.1111/j.1600-0536.1993.tb03512.x. [PMID: 8222626] - M Kosaka, T Ueda, M Yoshida, I Hara. [Assessment of occupational exposure to p-tert-butylphenol in synthetic resin factories].
Sangyo igaku. Japanese journal of industrial health.
1991 May; 33(3):186-95. doi:
10.1539/joh1959.33.186. [PMID: 1880965] - M Kosaka, T Ueda, M Yoshida, I Hara. Urinary metabolite levels in workers handling p-tert-butylphenol as an index of personal exposure.
International archives of occupational and environmental health.
1989; 61(7):451-5. doi:
10.1007/bf00386478. [PMID: 2777389] - S Nakayama, I Kawashima, T Kasahara, K Sakamoto. Effects of p-tert-butylphenyl trans-4-guanidinomethylcyclohexane carboxylate hydrochloride (NCO-650) and its metabolite, p-tert-butylphenol(BP) on drug-metabolizing enzymes and fine structure in rat liver.
The Journal of toxicological sciences.
1988 May; 13(2):71-81. doi:
10.2131/jts.13.71. [PMID: 3172284] - G P BABNOV, N G AGAFONOV. [PROBLEMS OF OCCUPATIONAL HYGIENE IN THE PRODUCTION OF 100 PER CENT SYNTHETIC RESINS MANUFACTURED USING P-TERT-BUTYLPHENOL AND FORMALDEHYDE AS THE BASE].
Gigiena truda i professional'nye zabolevaniia.
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. [PMID: 14069691]
