2-C-methyl-D-erythritol-4-phosphate (BioDeep_00000008650)
Secondary id: BioDeep_00001872463
human metabolite natural product
代谢物信息卡片
[(2R,3S)-2,3,4-trihydroxy-3-methylbutoxy]phosphonic acid
化学式: C5H13O7P (216.0399)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(otcml) 20.68%
分子结构信息
SMILES: C([C@]([C@H](O)COP(=O)(O)O)(C)O)O
InChI: InChI=1S/C5H13O7P/c1-5(8,3-6)4(7)2-12-13(9,10)11/h4,6-8H,2-3H2,1H3,(H2,9,10,11)/t4-,5+/m1/s1
描述信息
2-c-methyl-d-erythritol-4-phosphate is a member of the class of compounds known as monoalkyl phosphates. Monoalkyl phosphates are organic compounds containing a phosphate group that is linked to exactly one alkyl chain. 2-c-methyl-d-erythritol-4-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). 2-c-methyl-d-erythritol-4-phosphate can be found in a number of food items such as tea, narrowleaf cattail, chickpea, and rocket salad (sspecies), which makes 2-c-methyl-d-erythritol-4-phosphate a potential biomarker for the consumption of these food products.
同义名列表
11 个代谢物同义名
[(2R,3S)-2,3,4-trihydroxy-3-methylbutoxy]phosphonic acid; (2R,3S)-2,3,4-trihydroxy-3-methylbutoxyphosphonic acid; 2-C-Methyl-D-erythritol 4-phosphoric acid; 2-c-Methyl-D-erythritol-4-phosphoric acid; 2-C-Methyl-D-erythritol-4-phosphate; 2-C-Methyl-D-erythritol 4-phosphate; 2-C-Methylerythritol 4-phosphate; Methyl-D-erythritol Phosphate; Methyl-erythritol-4-phosphate; SCHEMBL21410636; MEP
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:17764
- KEGG: C11434
- PubChem: 443198
- PubChem: 31
- HMDB: HMDB0304061
- Metlin: METLIN64013
- MetaCyc: 2-C-METHYL-D-ERYTHRITOL-4-PHOSPHATE
- KNApSAcK: C00007297
- foodb: FDB030325
- chemspider: 391470
- CAS: 206440-72-4
- PMhub: MS000022323
- PubChem: 13606
- 3DMET: B04262
- NIKKAJI: J865.583I
- LOTUS: LTS0095389
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
243 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(243)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
9-mercaptodethiobiotin ⟶ Btn - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
4-CDP-2-C-methyl-D-erythritol + ATP ⟶ 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
4-CDP-2-C-methyl-D-erythritol + ATP ⟶ 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - DXP pathway:
1-deoxy-D-xylulose 5-phosphate + TPNH ⟶ 2-C-methyl-D-erythritol-4-phosphate + TPN
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
30 个相关的物种来源信息
- 3701 - Arabidopsis: LTS0095389
- 3702 - Arabidopsis thaliana: 10.1007/S00425-002-0762-0
- 3702 - Arabidopsis thaliana: 10.1007/S00425-002-0840-3
- 3702 - Arabidopsis thaliana: LTS0095389
- 6656 - Arthropoda: LTS0095389
- 4686 - Asparagus officinalis: 10.1371/JOURNAL.PONE.0219973
- 6658 - Branchiopoda: LTS0095389
- 3700 - Brassicaceae: LTS0095389
- 6668 - Daphnia: LTS0095389
- 6669 - Daphnia pulex: 10.1038/SREP25125
- 6669 - Daphnia pulex: LTS0095389
- 77658 - Daphniidae: LTS0095389
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
- 33682 - Euglenozoa: LTS0095389
- 2759 - Eukaryota: LTS0095389
- 9606 - Homo sapiens: -
- 5653 - Kinetoplastea: LTS0095389
- 3398 - Magnoliopsida: LTS0095389
- 33208 - Metazoa: LTS0095389
- 4070 - Solanaceae: LTS0095389
- 4107 - Solanum: LTS0095389
- 4081 - Solanum lycopersicum: 10.1038/SDATA.2014.29
- 4081 - Solanum lycopersicum: LTS0095389
- 35493 - Streptophyta: LTS0095389
- 58023 - Tracheophyta: LTS0095389
- 5690 - Trypanosoma: LTS0095389
- 5691 - Trypanosoma brucei: 10.1128/AAC.00044-13
- 5691 - Trypanosoma brucei: LTS0095389
- 5654 - Trypanosomatidae: LTS0095389
- 33090 - Viridiplantae: LTS0095389
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Diego González-Cabanelas, Erica Perreca, Johann M Rohwer, Axel Schmidt, Tobias Engl, Bettina Raguschke, Jonathan Gershenzon, Louwrance P Wright. Deoxyxylulose 5-Phosphate Synthase Does Not Play a Major Role in Regulating the Methylerythritol 4-Phosphate Pathway in Poplar.
International journal of molecular sciences.
2024 Apr; 25(8):. doi:
10.3390/ijms25084181. [PMID: 38673766] - Xin Wu, Mengwei Bu, Zili Yang, Hongrui Ping, Chunlin Song, Jiang Duan, Aidong Zhang. Design and Synthesis of Fosmidomycin Analogs containing aza-Linkers and Their Biological Activity Evaluation.
Pest management science.
2023 Oct; ?(?):. doi:
10.1002/ps.7810. [PMID: 37794283] - Fan Jiang, Dongying Liu, Jingqi Dai, Tao Yang, Jinzhu Zhang, Daidi Che, Jinping Fan. Cloning and Functional Characterization of 2-C-methyl-D-erythritol-4-phosphate cytidylyltransferase (LiMCT) Gene in Oriental Lily (Lilium 'Sorbonne').
Molecular biotechnology.
2023 Apr; ?(?):. doi:
10.1007/s12033-023-00729-8. [PMID: 37014586] - Daven B Khana, Mehmet Tatli, Julio Rivera Vazquez, Sarathi M Weraduwage, Noah Stern, Alexander S Hebert, Edna Angelica Trujillo, David M Stevenson, Joshua J Coon, Thomas D Sharky, Daniel Amador-Noguez. Systematic Analysis of Metabolic Bottlenecks in the Methylerythritol 4-Phosphate (MEP) Pathway of Zymomonas mobilis.
mSystems.
2023 Mar; ?(?):e0009223. doi:
10.1128/msystems.00092-23. [PMID: 36995223] - Shuai Wang, Yumei Feng, Yin Lou, Jingping Niu, Congcong Yin, Jinzhong Zhao, Weijun Du, Aiqin Yue. 3-Hydroxy-3-methylglutaryl coenzyme A reductase genes from Glycine max regulate plant growth and isoprenoid biosynthesis.
Scientific reports.
2023 03; 13(1):3902. doi:
10.1038/s41598-023-30797-4. [PMID: 36890158] - Toni Krause, Piera Wiesinger, Diego González-Cabanelas, Nathalie Lackus, Tobias G Köllner, Thomas Klüpfel, Jonathan Williams, Johann Rohwer, Jonathan Gershenzon, Axel Schmidt. HDR, the last enzyme in the MEP pathway, differently regulates isoprenoid biosynthesis in two woody plants.
Plant physiology.
2023 Feb; ?(?):. doi:
10.1093/plphys/kiad110. [PMID: 36848194] - Garima Pathak, Shivanand S Dudhagi, Saumya Raizada, Rajesh K Singh, A P Sane, Vidhu A Sane. Phosphomevalonate kinase regulates the MVA/MEP pathway in mango during ripening.
Plant physiology and biochemistry : PPB.
2023 Jan; 196(?):174-185. doi:
10.1016/j.plaphy.2023.01.030. [PMID: 36724702] - Xueni Di, David Ortega-Alarcon, Ramu Kakumanu, Javier Iglesias-Fernandez, Lucia Diaz, Edward E K Baidoo, Adrian Velazquez-Campoy, Manuel Rodríguez-Concepción, Jordi Perez-Gil. MEP pathway products allosterically promote monomerization of deoxy-D-xylulose-5-phosphate synthase to feedback-regulate their supply.
Plant communications.
2022 Dec; ?(?):100512. doi:
10.1016/j.xplc.2022.100512. [PMID: 36575800] - Ying-Ping Huang, I-Hsuan Chen, Yu-Shun Kao, Yau-Heiu Hsu, Ching-Hsiu Tsai. The gibberellic acid derived from the plastidial MEP pathway is involved in the accumulation of Bamboo mosaic virus.
The New phytologist.
2022 08; 235(4):1543-1557. doi:
10.1111/nph.18210. [PMID: 35524450] - Yong Yuan, Siyan Ren, Xiaofeng Liu, Liyang Su, Yu Wu, Wen Zhang, Yan Li, Yidan Jiang, Hsihua Wang, Rao Fu, Mondher Bouzayen, Mingchun Liu, Yang Zhang. SlWRKY35 positively regulates carotenoid biosynthesis by activating the MEP pathway in tomato fruit.
The New phytologist.
2022 04; 234(1):164-178. doi:
10.1111/nph.17977. [PMID: 35048386] - Bin Liu, Lu Zhang, Linda Rusalepp, Eve Kaurilind, Hassan Yusuf Sulaiman, Tõnu Püssa, Ülo Niinemets. Heat priming improved heat tolerance of photosynthesis, enhanced terpenoid and benzenoid emission and phenolics accumulation in Achillea millefolium.
Plant, cell & environment.
2021 07; 44(7):2365-2385. doi:
10.1111/pce.13830. [PMID: 32583881] - Wu Wang, Jiao Feng, Lingling Wei, Muhammad Khalil-Ur-Rehman, Niels J Nieuwenhuizen, Lina Yang, Huan Zheng, Jianmin Tao. Transcriptomics Integrated with Free and Bound Terpenoid Aroma Profiling during 'Shine Muscat' (Vitis labrusca × V. vinifera) Grape Berry Development Reveals Coordinate Regulation of MEP Pathway and Terpene Synthase Gene Expression.
Journal of agricultural and food chemistry.
2021 Feb; 69(4):1413-1429. doi:
10.1021/acs.jafc.0c06591. [PMID: 33481572] - Yifeng Zhang, Yujun Zhao, Jiadian Wang, Tianyuan Hu, Yuru Tong, Jiawei Zhou, Jie Gao, Luqi Huang, Wei Gao. The expression of TwDXS in the MEP pathway specifically affects the accumulation of triptolide.
Physiologia plantarum.
2020 May; 169(1):40-48. doi:
10.1111/ppl.13051. [PMID: 31758560] - M K You, Y J Lee, J K Kim, S A Baek, Y A Jeon, S H Lim, S H Ha. The organ-specific differential roles of rice DXS and DXR, the first two enzymes of the MEP pathway, in carotenoid metabolism in Oryza sativa leaves and seeds.
BMC plant biology.
2020 Apr; 20(1):167. doi:
10.1186/s12870-020-02357-9. [PMID: 32293285] - Enrico Orsi, Jules Beekwilder, Siebe Peek, Gerrit Eggink, Servé W M Kengen, Ruud A Weusthuis. Metabolic flux ratio analysis by parallel 13C labeling of isoprenoid biosynthesis in Rhodobacter sphaeroides.
Metabolic engineering.
2020 01; 57(?):228-238. doi:
10.1016/j.ymben.2019.12.004. [PMID: 31843486] - Matthew E Bergman, Benjamin Davis, Michael A Phillips. Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action.
Molecules (Basel, Switzerland).
2019 Nov; 24(21):. doi:
10.3390/molecules24213961. [PMID: 31683764] - Garima Ayachit, Inayatullah Shaikh, Preeti Sharma, Bhavika Jani, Labdhi Shukla, Priyanka Sharma, Shivarudrappa B Bhairappanavar, Chaitanya Joshi, Jayashankar Das. De novo transcriptome of Gymnema sylvestre identified putative lncRNA and genes regulating terpenoid biosynthesis pathway.
Scientific reports.
2019 10; 9(1):14876. doi:
10.1038/s41598-019-51355-x. [PMID: 31619732] - Le Xue, Zilong He, Xiaochun Bi, Wei Xu, Ting Wei, Shuangxiu Wu, Songnian Hu. Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng.
BMC genomics.
2019 May; 20(1):383. doi:
10.1186/s12864-019-5718-x. [PMID: 31101014] - Thiagarayaselvam Aarthy, Fayaj A Mulani, Avinash Pandreka, Ashish Kumar, Sharvani S Nandikol, Saikat Haldar, Hirekodathakallu V Thulasiram. Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension.
BMC plant biology.
2018 Oct; 18(1):230. doi:
10.1186/s12870-018-1447-6. [PMID: 30314459] - Julia Emiliani, Lucio D'Andrea, María Lorena Falcone Ferreyra, Evangelina Maulión, Eduardo Rodriguez, Manuel Rodriguez-Concepción, Paula Casati. A role for β,β-xanthophylls in Arabidopsis UV-B photoprotection.
Journal of experimental botany.
2018 09; 69(20):4921-4933. doi:
10.1093/jxb/ery242. [PMID: 29945243] - Hidenobu Uchida, Koremitsu Sumimoto, Tomoka Oki, Ichiro Nishii, Eiichi Mizohata, Shigeki Matsunaga, Shigeru Okada. Isolation and characterization of 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene from Botryococcus braunii, race B.
Journal of plant research.
2018 Sep; 131(5):839-848. doi:
10.1007/s10265-018-1039-4. [PMID: 29725892] - Mariaevelina Alfieri, Maria Carmela Vaccaro, Elisa Cappetta, Alfredo Ambrosone, Nunziatina De Tommasi, Antonietta Leone. Coactivation of MEP-biosynthetic genes and accumulation of abietane diterpenes in Salvia sclarea by heterologous expression of WRKY and MYC2 transcription factors.
Scientific reports.
2018 07; 8(1):11009. doi:
10.1038/s41598-018-29389-4. [PMID: 30030474] - Rui Huang, Yang Wang, Pingrong Wang, Chunmei Li, Fuliang Xiao, Nenggang Chen, Na Li, Caixia Li, Changhui Sun, Lihua Li, Rongjun Chen, Zhengjun Xu, Jianqing Zhu, Xiaojian Deng. A single nucleotide mutation of IspF gene involved in the MEP pathway for isoprenoid biosynthesis causes yellow-green leaf phenotype in rice.
Plant molecular biology.
2018 Jan; 96(1-2):5-16. doi:
10.1007/s11103-017-0668-7. [PMID: 29143298] - Adam Jozwiak, Agata Lipko, Magdalena Kania, Witold Danikiewicz, Liliana Surmacz, Agnieszka Witek, Jacek Wojcik, Konrad Zdanowski, Cezary Pączkowski, Tadeusz Chojnacki, Jaroslaw Poznanski, Ewa Swiezewska. Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis.
Plant physiology.
2017 Jun; 174(2):857-874. doi:
10.1104/pp.17.00036. [PMID: 28385729] - Xin Wang, Wei Liu, Changpeng Xin, Yi Zheng, Yanbing Cheng, Su Sun, Runze Li, Xin-Guang Zhu, Susie Y Dai, Peter M Rentzepis, Joshua S Yuan. Enhanced limonene production in cyanobacteria reveals photosynthesis limitations.
Proceedings of the National Academy of Sciences of the United States of America.
2016 12; 113(50):14225-14230. doi:
10.1073/pnas.1613340113. [PMID: 27911807] - Y Shivani, Y Subhash, Ch Sasikala, Ch V Ramana. Description of 'Candidatus Marispirochaeta associata' and reclassification of Spirochaeta bajacaliforniensis, Spirochaeta smaragdinae and Spirochaeta sinaica to a new genus Sediminispirochaeta gen. nov. as Sediminispirochaeta bajacaliforniensis comb. nov., Sediminispirochaeta smaragdinae comb. nov. and Sediminispirochaeta sinaica comb. nov.
International journal of systematic and evolutionary microbiology.
2016 Dec; 66(12):5485-5492. doi:
10.1099/ijsem.0.001545. [PMID: 27902269] - Han Zheng, Li Jing, Na Yao, Qing-shan Yang, Hua-sheng Peng, Ye Shen, Lu-qi Huang. [Cloning and expression analysis of 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene (CcDXR1) in Cinnamomum camphora L.) Presl].
Yao xue xue bao = Acta pharmaceutica Sinica.
2016 09; 51(9):1494-501. doi:
. [PMID: 29924561] - Chen Yang, Xiang Gao, Yu Jiang, Bingbing Sun, Fang Gao, Sheng Yang. Synergy between methylerythritol phosphate pathway and mevalonate pathway for isoprene production in Escherichia coli.
Metabolic engineering.
2016 09; 37(?):79-91. doi:
10.1016/j.ymben.2016.05.003. [PMID: 27174717] - Geoffrey Benn, Marta Bjornson, Haiyan Ke, Amancio De Souza, Edward I Balmond, Jared T Shaw, Katayoon Dehesh. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3.
Proceedings of the National Academy of Sciences of the United States of America.
2016 08; 113(31):8855-60. doi:
10.1073/pnas.1602582113. [PMID: 27432993] - Alexandre Huchelmann, Mathieu Semir Brahim, Esther Gerber, Denis Tritsch, Thomas J Bach, Andréa Hemmerlin. Farnesol-mediated shift in the metabolic origin of prenyl groups used for protein prenylation in plants.
Biochimie.
2016 Aug; 127(?):95-102. doi:
10.1016/j.biochi.2016.04.021. [PMID: 27138105] - Min Shi, Xiuqin Luo, Guanhua Ju, Leilei Li, Shengxiong Huang, Tong Zhang, Huizhong Wang, Guoyin Kai. Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering.
Journal of agricultural and food chemistry.
2016 Mar; 64(12):2523-30. doi:
10.1021/acs.jafc.5b04697. [PMID: 26753746] - Yan Liu, Shi-Hong Luo, Axel Schmidt, Guo-Dong Wang, Gui-Ling Sun, Marcus Grant, Ce Kuang, Min-Jie Yang, Shu-Xi Jing, Chun-Huan Li, Bernd Schneider, Jonathan Gershenzon, Sheng-Hong Li. A Geranylfarnesyl Diphosphate Synthase Provides the Precursor for Sesterterpenoid (C25) Formation in the Glandular Trichomes of the Mint Species Leucosceptrum canum.
The Plant cell.
2016 Mar; 28(3):804-22. doi:
10.1105/tpc.15.00715. [PMID: 26941091] - D González-Cabanelas, A Hammerbacher, B Raguschke, J Gershenzon, L P Wright. Quantifying the Metabolites of the Methylerythritol 4-Phosphate (MEP) Pathway in Plants and Bacteria by Liquid Chromatography-Triple Quadrupole Mass Spectrometry.
Methods in enzymology.
2016; 576(?):225-49. doi:
10.1016/bs.mie.2016.02.025. [PMID: 27480689] - Mi Jung Kim, Jingjing Jin, Junshi Zheng, Limsoon Wong, Nam-Hai Chua, In-Cheol Jang. Comparative Transcriptomics Unravel Biochemical Specialization of Leaf Tissues of Stevia for Diterpenoid Production.
Plant physiology.
2015 Dec; 169(4):2462-80. doi:
10.1104/pp.15.01353. [PMID: 26438788] - Yu-ru Tong, Ping Su, Meng Zhang, Yu-jun Zhao, Xiu-juan Wang, Wei Gao, Lu-qi Huang. [Cloning and expression analysis of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene in Tripterygium wilfordii].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2015 Nov; 40(22):4378-83. doi:
". [PMID: 27097410] - Manuel Rodríguez-Concepción, Albert Boronat. Breaking new ground in the regulation of the early steps of plant isoprenoid biosynthesis.
Current opinion in plant biology.
2015 Jun; 25(?):17-22. doi:
10.1016/j.pbi.2015.04.001. [PMID: 25909859] - Alexandra Pokhilko, Jordi Bou-Torrent, Pablo Pulido, Manuel Rodríguez-Concepción, Oliver Ebenhöh. Mathematical modelling of the diurnal regulation of the MEP pathway in Arabidopsis.
The New phytologist.
2015 May; 206(3):1075-1085. doi:
10.1111/nph.13258. [PMID: 25598499] - Xuhong Du, Chenlu Zhang, Wanli Guo, Weibo Jin, Zongsuo Liang, Xijun Yan, Zhixin Guo, Yan Liu, Dongfeng Yang. Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots.
Molecules (Basel, Switzerland).
2015 Apr; 20(5):7574-85. doi:
10.3390/molecules20057574. [PMID: 25919278] - J Lv, G S Liu, W Li, Z Hussian, Y H Sun. Cloning and expression analysis of terpenoid metabolism-related gene NsyCMS in Nicotiana sylvestris.
Genetics and molecular research : GMR.
2015 Apr; 14(2):3300-8. doi:
10.4238/2015.april.13.9. [PMID: 25966096] - Shantanu Mandal, Shivangi Upadhyay, Ved Pal Singh, Rupam Kapoor. Enhanced production of steviol glycosides in mycorrhizal plants: a concerted effect of arbuscular mycorrhizal symbiosis on transcription of biosynthetic genes.
Plant physiology and biochemistry : PPB.
2015 Apr; 89(?):100-6. doi:
10.1016/j.plaphy.2015.02.010. [PMID: 25734328] - Niels J Nieuwenhuizen, Xiuyin Chen, Mindy Y Wang, Adam J Matich, Ramon Lopez Perez, Andrew C Allan, Sol A Green, Ross G Atkinson. Natural variation in monoterpene synthesis in kiwifruit: transcriptional regulation of terpene synthases by NAC and ETHYLENE-INSENSITIVE3-like transcription factors.
Plant physiology.
2015 Apr; 167(4):1243-58. doi:
10.1104/pp.114.254367. [PMID: 25649633] - Diego González-Cabanelas, Louwrance P Wright, Christian Paetz, Nawaporn Onkokesung, Jonathan Gershenzon, Manuel Rodríguez-Concepción, Michael A Phillips. The diversion of 2-C-methyl-D-erythritol-2,4-cyclodiphosphate from the 2-C-methyl-D-erythritol 4-phosphate pathway to hemiterpene glycosides mediates stress responses in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology.
2015 Apr; 82(1):122-37. doi:
10.1111/tpj.12798. [PMID: 25704332] - Abdellatif Bahaji, Ángela M Sánchez-López, Nuria De Diego, Francisco J Muñoz, Edurne Baroja-Fernández, Jun Li, Adriana Ricarte-Bermejo, Marouane Baslam, Iker Aranjuelo, Goizeder Almagro, Jan F Humplík, Ondřej Novák, Lukáš Spíchal, Karel Doležal, Javier Pozueta-Romero. Plastidic phosphoglucose isomerase is an important determinant of starch accumulation in mesophyll cells, growth, photosynthetic capacity, and biosynthesis of plastidic cytokinins in Arabidopsis.
PloS one.
2015; 10(3):e0119641. doi:
10.1371/journal.pone.0119641. [PMID: 25811607] - Shefali Singh, Shaifali Pal, Karuna Shanker, Chandan Singh Chanotiya, Madan Mohan Gupta, Upendra Nath Dwivedi, Ajit Kumar Shasany. Sterol partitioning by HMGR and DXR for routing intermediates toward withanolide biosynthesis.
Physiologia plantarum.
2014 Dec; 152(4):617-33. doi:
10.1111/ppl.12213. [PMID: 24749735] - Cinzia Formighieri, Anastasios Melis. Carbon partitioning to the terpenoid biosynthetic pathway enables heterologous β-phellandrene production in Escherichia coli cultures.
Archives of microbiology.
2014 Dec; 196(12):853-61. doi:
10.1007/s00203-014-1024-9. [PMID: 25116411] - Isabel Mendoza-Poudereux, Jesús Muñoz-Bertomeu, Isabel Arrillaga, Juan Segura. Deoxyxylulose 5-phosphate reductoisomerase is not a rate-determining enzyme for essential oil production in spike lavender.
Journal of plant physiology.
2014 Nov; 171(17):1564-70. doi:
10.1016/j.jplph.2014.07.012. [PMID: 25151124] - Sergiy G Krasutsky, Marek Urbansky, Chad E Davis, Christian Lherbet, Robert M Coates, C Dale Poulter. Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens.
The Journal of organic chemistry.
2014 Oct; 79(19):9170-8. doi:
10.1021/jo501529k. [PMID: 25184438] - Hiroshi Kiyota, Yukiko Okuda, Michiho Ito, Masami Yokota Hirai, Masahiko Ikeuchi. Engineering of cyanobacteria for the photosynthetic production of limonene from CO2.
Journal of biotechnology.
2014 Sep; 185(?):1-7. doi:
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Journal of experimental botany.
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