530-55-2 (BioDeep_00000863685)

PANOMIX_OTCML-2023

代谢物信息卡片

2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy-, radical ion(1-)

化学式: C8H8O4 (168.0422568)
中文名称: 2,6-二甲氧基-1,4-苯醌
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=O)C=C(C1=O)OC
InChI: InChI=1S/C8H8O4/c1-11-6-3-5(9)4-7(12-2)8(6)10/h3-4H,1-2H3

描述信息

2,6-Dimethoxy-1,4-benzoquinone, a natural phytochemical, is a known haustorial inducing factor. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimalaria effects[1].
2,6-Dimethoxy-1,4-benzoquinone, a natural phytochemical, is a known haustorial inducing factor. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimalaria effects[1].

同义名列表

49 个代谢物同义名

2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy-, radical ion(1-); 2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy- (9CI); 2,5-Cyclohexadiene-1,4-dione, 2,6-dimethoxy-; 2,6-dimethoxycyclohexa-2,5-diene-1,4-dione; 2,6-Dimethoxysemiquinone radicals; 2,6-Dimethoxysemiquinone anions; 2,6-Dimethoxy-1,4-benzoquinone; p-Benzoquinone, 2,6-dimethoxy-; 2,6-Dimethoxybenzo-1,4-quinone; 2,6-dimethoxy-p-benzoquinone; DIMETHOXYBENZOQUINONE,2,6-; 2,6-Dimethoxybenzoquinone; 2,6-Dimethoxy-p-quinone; ghl.PD_Mitscher_leg0.4; SDCCGMLS-0066389.P001; 2,6-Dimethoxyquinone; Maybridge1_002628; Spectrum5_000335; Spectrum2_000781; Spectrum4_001608; EINECS 208-484-7; Spectrum3_000177; Spectrum_000723; NCGC00095215-01; NCGC00095215-02; 428566_ALDRICH; SPECTRUM200413; DivK1c_001380; KBioSS_001203; BSPBio_001673; KBioGR_001955; KBio2_006339; SPBio_000882; KBio2_003771; ZINC00137119; KBio2_001203; KBio3_001173; NCI60_001958; AIDS-011961; CDS1_000340; 26547-64-8; AIDS011961; ST5331798; NSC 24500; 530-55-2; NSC24500; NSC56336; C10331; DMBQ

数据库引用编号

5 个数据库交叉引用编号

PubChem: 68262
ChEMBL: CHEMBL448515
CAS: 26547-64-8
CAS: 530-55-2
medchemexpress: HY-N1677

分类词条

醌类

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

112 个相关的物种来源信息

354528 两面针: -
33090 麻黄: -
33090 荆芥: -
38871 秦皮: -
49314 Annona cherimola: 10.1002/JCCS.199900010
265783 Artemisia capillaris: 10.1016/S0968-0896(00)00225-X
1132458 Cinnamomum kotoense: 10.1021/NP0580210
1056465 Zanthoxylum beecheyanum: 10.1002/JCCS.200400159
4530 Oryza sativa: 10.3390/MOLECULES16031917
159976 Viscum coloratum: 10.1248/CPB.54.1063
3415 Liriodendron tulipifera: 10.1007/S10600-012-0141-4
332435 Lindera glauca: 10.1002/JCCS.200000050
56035 Fraxinus longicuspis:
53846 Caesalpinia pulcherrima:
210348 Brucea javanica:
344115 Neolitsea pulchella: 10.1021/NP010236W
2803928 Neolitsea acuminatissima: 10.1021/NP010236W
139932 Engelhardia roxburghiana: 10.1016/J.PHYTOCHEM.2007.01.018
544665 Hydnocarpus annamensis: 10.1055/S-2006-946678
62097 Plumeria rubra: 10.1055/S-0029-1240611
106626 Rhizophora apiculata: 10.1016/0031-9422(93)85036-Q
115466 Euterpe oleracea: 10.1021/JF801792N
2839963 Zanthoxylum asiaticum: 10.1016/S0031-9422(97)00678-X
53923 Senna alata: 10.1016/0031-9422(93)85192-T
1009467 Diospyros eriantha: 10.1002/JCCS.199400028
140964 Durio kutejensis:
1603837 Strobilanthes dimorphotricha: 10.1055/S-2005-873125
2068726 Ajania nubigena: 10.1002/PCA.995
262989 Strobilanthes formosana: 10.1002/JCCS.200400030
1604314 Gynura japonica: 10.1055/S-2003-42796
34317 Eucalyptus globulus: 10.1016/S0031-9422(96)00680-2
860794 Hypericum geminiflorum: 10.1016/S0031-9422(96)00644-9
204975 Pentaclethra eetveldeana: 10.1016/0031-9422(95)00944-2
1037036 Iris milesii: 10.1016/S0031-9422(00)80460-4
109063 Alnus japonica: 10.1016/0031-9422(81)83035-X
76276 Senecio vulgaris: 10.3184/030823410X12830855365409
697038 Melicope semecarpifolia: 10.1055/S-2005-871295
142181 Edgeworthia chrysantha: 10.1007/S10600-009-9230-4
73292 Helianthus heterophyllus: 10.1016/S0031-9422(00)81173-5
354528 Zanthoxylum nitidum: 10.1016/J.FOODCHEM.2010.09.069
415523 Triumfetta rhomboidea: 10.1002/JCCS.199500016
82096 Eleutherococcus senticosus: 10.1248/CPB.38.1763
1130856 Verbesina gigantea: 10.1016/0031-9422(81)85100-X
1620208 Verbesina virginica: 10.1016/0031-9422(81)85100-X
2508384 Kielmeyera rupestris: 10.1016/S0031-9422(00)85160-2
262954 Tapeinidium pinnatum: 10.1248/CPB.31.3865
2707461 Baccharis megapotamica: 10.1016/S0031-9422(00)85519-3
265785 Atractylodes macrocephala: 10.1007/S10600-011-9795-6
1157100 Enkianthus nudipes: 10.1248/CPB.24.2102
109849 Macaranga tanarius: 10.1016/0031-9422(88)80619-8
1226761 Berchemia racemosa: 10.1248/CPB.34.1333
1226760 Berchemia floribunda: 10.1248/CPB.34.1333
46985 Adonis vernalis: 10.1002/HLCA.19300130625
180953 Ulmus thomasii: 10.1016/S0040-4020(01)82782-4
1291627 Zanthoxylum gilletii: 10.1016/J.PHYTOCHEM.2006.12.015
2072778 Marsdenia tinctoria: 10.1248/YAKUSHI1947.98.9_1285
23110 Hydrangea macrophylla: 10.1271/BBB.58.2073
49314 Annona cherimola: 10.1002/JCCS.199900010
265783 Artemisia capillaris: 10.1016/S0968-0896(00)00225-X
1132458 Cinnamomum kotoense: 10.1021/NP0580210
1056465 Zanthoxylum beecheyanum: 10.1002/JCCS.200400159
4530 Oryza sativa: 10.3390/MOLECULES16031917
159976 Viscum coloratum: 10.1248/CPB.54.1063
3415 Liriodendron tulipifera: 10.1007/S10600-012-0141-4
332435 Lindera glauca: 10.1002/JCCS.200000050
56035 Fraxinus longicuspis:
53846 Caesalpinia pulcherrima:
210348 Brucea javanica:
344115 Neolitsea pulchella: 10.1021/NP010236W
2803928 Neolitsea acuminatissima: 10.1021/NP010236W
139932 Engelhardia roxburghiana: 10.1016/J.PHYTOCHEM.2007.01.018
544665 Hydnocarpus annamensis: 10.1055/S-2006-946678
62097 Plumeria rubra: 10.1055/S-0029-1240611
106626 Rhizophora apiculata: 10.1016/0031-9422(93)85036-Q
115466 Euterpe oleracea: 10.1021/JF801792N
2839963 Zanthoxylum asiaticum: 10.1016/S0031-9422(97)00678-X
53923 Senna alata: 10.1016/0031-9422(93)85192-T
1009467 Diospyros eriantha: 10.1002/JCCS.199400028
140964 Durio kutejensis:
1603837 Strobilanthes dimorphotricha: 10.1055/S-2005-873125
2068726 Ajania nubigena: 10.1002/PCA.995
262989 Strobilanthes formosana: 10.1002/JCCS.200400030
1604314 Gynura japonica: 10.1055/S-2003-42796
34317 Eucalyptus globulus: 10.1016/S0031-9422(96)00680-2
860794 Hypericum geminiflorum: 10.1016/S0031-9422(96)00644-9
204975 Pentaclethra eetveldeana: 10.1016/0031-9422(95)00944-2
1037036 Iris milesii: 10.1016/S0031-9422(00)80460-4
109063 Alnus japonica: 10.1016/0031-9422(81)83035-X
76276 Senecio vulgaris: 10.3184/030823410X12830855365409
697038 Melicope semecarpifolia: 10.1055/S-2005-871295
142181 Edgeworthia chrysantha: 10.1007/S10600-009-9230-4
73292 Helianthus heterophyllus: 10.1016/S0031-9422(00)81173-5
354528 Zanthoxylum nitidum: 10.1016/J.FOODCHEM.2010.09.069
415523 Triumfetta rhomboidea: 10.1002/JCCS.199500016
82096 Eleutherococcus senticosus: 10.1248/CPB.38.1763
1130856 Verbesina gigantea: 10.1016/0031-9422(81)85100-X
1620208 Verbesina virginica: 10.1016/0031-9422(81)85100-X
2508384 Kielmeyera rupestris: 10.1016/S0031-9422(00)85160-2
262954 Tapeinidium pinnatum: 10.1248/CPB.31.3865
2707461 Baccharis megapotamica: 10.1016/S0031-9422(00)85519-3
265785 Atractylodes macrocephala: 10.1007/S10600-011-9795-6
1157100 Enkianthus nudipes: 10.1248/CPB.24.2102
109849 Macaranga tanarius: 10.1016/0031-9422(88)80619-8
1226761 Berchemia racemosa: 10.1248/CPB.34.1333
1226760 Berchemia floribunda: 10.1248/CPB.34.1333
46985 Adonis vernalis: 10.1002/HLCA.19300130625
180953 Ulmus thomasii: 10.1016/S0040-4020(01)82782-4
1291627 Zanthoxylum gilletii: 10.1016/J.PHYTOCHEM.2006.12.015
2072778 Marsdenia tinctoria: 10.1248/YAKUSHI1947.98.9_1285
23110 Hydrangea macrophylla: 10.1271/BBB.58.2073
354528 Zanthoxylum Nitidum: -
33090 Plants: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Anuphon Laohavisit, Takanori Wakatake, Nobuaki Ishihama, Hugh Mulvey, Kaori Takizawa, Takamasa Suzuki, Ken Shirasu. Quinone perception in plants via leucine-rich-repeat receptor-like kinases. Nature. 2020 11; 587(7832):92-97. doi: 10.1038/s41586-020-2655-4. [PMID: 32879491]
Christoph Otto, Theresa Hahlbrock, Kilian Eich, Ferdi Karaaslan, Constantin Jürgens, Christoph-Thomas Germer, Armin Wiegering, Ulrike Kämmerer. Antiproliferative and antimetabolic effects behind the anticancer property of fermented wheat germ extract. BMC complementary and alternative medicine. 2016 Jun; 16(?):160. doi: 10.1186/s12906-016-1138-5. [PMID: 27245162]
Songkui Cui, Takanori Wakatake, Kei Hashimoto, Simon B Saucet, Kiminori Toyooka, Satoko Yoshida, Ken Shirasu. Haustorial Hairs Are Specialized Root Hairs That Support Parasitism in the Facultative Parasitic Plant Phtheirospermum japonicum. Plant physiology. 2016 Mar; 170(3):1492-503. doi: 10.1104/pp.15.01786. [PMID: 26712864]
Patricia L Judson, Entidhar Al Sawah, Douglas C Marchion, Yin Xiong, Elona Bicaku, Nadim Bou Zgheib, Hye Sook Chon, Xiaomang B Stickles, Ardeshir Hakam, Robert M Wenham, Sachin M Apte, Jesus Gonzalez-Bosquet, Dung-Tsa Chen, Johnathan M Lancaster. Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. 2012 Jul; 22(6):960-7. doi: 10.1097/igc.0b013e318258509d. [PMID: 22740002]
Netiya Karaket, Kanyaratt Supaibulwatana, Supatsara Ounsuk, Valérie Bultel-Poncé, Van Cuong Pham, Bernard Bodo. Chemical and bioactivity evaluation of the bark of Neonauclea purpurea. Natural product communications. 2012 Feb; 7(2):169-70. doi: . [PMID: 22474944]
Pradeepa C G Bandaranayake, Alexey Tomilov, Natalya B Tomilova, Quy A Ngo, Norman Wickett, Claude W dePamphilis, John I Yoder. The TvPirin gene is necessary for haustorium development in the parasitic plant Triphysaria versicolor. Plant physiology. 2012 Feb; 158(2):1046-53. doi: 10.1104/pp.111.186858. [PMID: 22128136]
Nikolai Scherbak, Anneli Ala-Häivälä, Mikael Brosché, Nathalie Böwer, Hilja Strid, John R Gittins, Elin Grahn, Leif A Eriksson, Åke Strid. The pea SAD short-chain dehydrogenase/reductase: quinone reduction, tissue distribution, and heterologous expression. Plant physiology. 2011 Apr; 155(4):1839-50. doi: 10.1104/pp.111.173336. [PMID: 21343423]
Juliane K Ishida, Satoko Yoshida, Masaki Ito, Shigetou Namba, Ken Shirasu. Agrobacterium rhizogenes-mediated transformation of the parasitic plant Phtheirospermum japonicum. PloS one. 2011; 6(10):e25802. doi: 10.1371/journal.pone.0025802. [PMID: 21991355]
Pedro Sanchez-Cruz, Carmelo Garcia, Antonio E Alegria. Role of quinones in the ascorbate reduction rates of S-nitrosoglutathione. Free radical biology & medicine. 2010 Nov; 49(9):1387-94. doi: 10.1016/j.freeradbiomed.2010.07.022. [PMID: 20691779]
Myung-Hee Kim, Sung-Hoon Jo, Kyung-Soo Ha, Ji-Hye Song, Hae-Dong Jang, Young-In Kwon. Antimicrobial activities of 1,4-benzoquinones and wheat germ extract. Journal of microbiology and biotechnology. 2010 Aug; 20(8):1204-9. doi: 10.4014/jmb.1004.04037. [PMID: 20798583]
Guy Merlin Kuigoua, Simeon F Kouam, Bonaventure T Ngadjui, Barbara Schulz, Ivan R Green, M Iqbal Choudhary, Karsten Krohn. Minor secondary metabolic products from the stem bark of Plumeria rubra Linn. displaying antimicrobial activities. Planta medica. 2010 Apr; 76(6):620-5. doi: 10.1055/s-0029-1240611. [PMID: 19937550]
Rickie B Turley, Earl Taliercio. Cotton benzoquinone reductase: up-regulation during early fiber development and heterologous expression and characterization in Pichia pastoris. Plant physiology and biochemistry : PPB. 2008 Aug; 46(8-9):780-5. doi: 10.1016/j.plaphy.2008.04.016. [PMID: 18534861]
Xiao-lan Wang, Kai-bei Yu, Shu-lin Peng. [Chemical constituents of aerial part of Acalypha australis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Jun; 33(12):1415-7. doi: . [PMID: 18837345]
James T Heimbach, Gyula Sebestyen, Gabor Semjen, Elke Kennepohl. Safety studies regarding a standardized extract of fermented wheat germ. International journal of toxicology. 2007 May; 26(3):253-9. doi: 10.1080/10915810701369709. [PMID: 17564907]
Yao-Lan Li, Guan Wang, Jun-Yi Xue, Ying-Zhou Cen. [Studies on chemical constituents from Serissa serissoides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Apr; 32(7):605-8. doi: ". [PMID: 17583202]
Luc Meva'a Mbaze, Herve Martial P Poumale, Jean Duplex Wansi, Jean Alexandre Lado, Shamsun Nahar Khan, Muhammad Choudhary Iqbal, Bonaventure Tchaleu Ngadjui, Hartmut Laatsch. alpha-Glucosidase inhibitory pentacyclic triterpenes from the stem bark of Fagara tessmannii (Rutaceae). Phytochemistry. 2007 Mar; 68(5):591-5. doi: 10.1016/j.phytochem.2006.12.015. [PMID: 17270224]
Rudiyansyah, Mary J Garson. Secondary metabolites from the wood bark of Durio zibethinus and Durio kutejensis. Journal of natural products. 2006 Aug; 69(8):1218-21. doi: 10.1021/np050553t. [PMID: 16933881]
Manuel J Torres, Alexey A Tomilov, Natalya Tomilova, Russell L Reagan, John I Yoder. Pscroph, a parasitic plant EST database enriched for parasite associated transcripts. BMC plant biology. 2005 Nov; 5(?):24. doi: 10.1186/1471-2229-5-24. [PMID: 16288663]
Ru-Wei Lin, Ian-Lih Tsai, Chang-Yih Duh, Kuo-Hsiung Lee, Ih-Sheng Chen. New lignans and cytotoxic constituents from Wikstroemia lanceolata. Planta medica. 2004 Mar; 70(3):234-8. doi: 10.1055/s-2004-815540. [PMID: 15114500]
F Jakab, Y Shoenfeld, A Balogh, M Nichelatti, A Hoffmann, Zs Kahán, K Lapis, A Mayer, P Sápy, F Szentpétery, A Telekes, L Thurzó, A Vágvölgyi, M Hidvégi. A medical nutriment has supportive value in the treatment of colorectal cancer. British journal of cancer. 2003 Aug; 89(3):465-9. doi: 10.1038/sj.bjc.6601153. [PMID: 12888813]
Wei-Yu Lin, Yueh-Hsiung Kuo, Ya-Ling Chang, Che-Ming Teng, Eng-Chi Wang, Tsutomu Ishikawa, Ih-Sheng Chen. Anti-platelet aggregation and chemical constituents from the rhizome of Gynura japonica. Planta medica. 2003 Aug; 69(8):757-64. doi: 10.1055/s-2003-42796. [PMID: 14531028]
Fang-Rong Chang, Tian-Jye Hsieh, Ti-Lung Huang, Chung-Yi Chen, Reen-Yen Kuo, Yuh-Chwen Chang, Hui-Fen Chiu, Yang-Chang Wu. Cytotoxic constituents of the stem bark of Neolitsea acuminatissima. Journal of natural products. 2002 Mar; 65(3):255-8. doi: 10.1021/np010236w. [PMID: 11908960]
Mei-Ing Chung, Jing-Ru Weng, Jih-Pyang Wang, Che-Ming Teng, Chun-Nan Lin. Antiplatelet and anti-inflammatory constituents and new oxygenated xanthones from Hypericum geminiflorum. Planta medica. 2002 Jan; 68(1):25-9. doi: 10.1055/s-2002-19871. [PMID: 11842322]
A Zalatnai, K Lapis, B Szende, E Rásó, A Telekes, Resetár A, M Hidvégi. Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats. Carcinogenesis. 2001 Oct; 22(10):1649-52. doi: 10.1093/carcin/22.10.1649. [PMID: 11577004]
M Matvienko, M J Torres, J I Yoder. Transcriptional responses in the hemiparasitic plant Triphysaria versicolor to host plant signals. Plant physiology. 2001 Sep; 127(1):272-82. doi: 10.1104/pp.127.1.272. [PMID: 11553755]
T Estlander, R Jolanki, K Alanko, L Kanerva. Occupational allergic contact dermatitis caused by wood dusts. Contact dermatitis. 2001 Apr; 44(4):213-7. doi: 10.1034/j.1600-0536.2001.044004213.x. [PMID: 11260236]
R L Wrobel, J I Yoder. Differential RNA expression of alpha-expansin gene family members in the parasitic angiosperm Triphysaria versicolor (Scrophulariaceae). Gene. 2001 Mar; 266(1-2):85-93. doi: 10.1016/s0378-1119(01)00376-6. [PMID: 11290422]
M Matvienko, A Wojtowicz, R Wrobel, D Jamison, Y Goldwasser, J I Yoder. Quinone oxidoreductase message levels are differentially regulated in parasitic and non-parasitic plants exposed to allelopathic quinones. The Plant journal : for cell and molecular biology. 2001 Feb; 25(4):375-87. doi: 10.1046/j.1365-313x.2001.00971.x. [PMID: 11260494]
G Brambilla, L Robbiano, E Cajelli, A Martelli, F Turmolini, M Mazzei. Cytotoxic, DNA-damaging and mutagenic properties of 2,6-dimethoxy-1,4-benzoquinone, formed by dimethophrine-nitrite interaction. The Journal of pharmacology and experimental therapeutics. 1988 Mar; 244(3):1011-5. doi: . [PMID: 3252018]
B M Hausen, A Shoji, O Jarchow. Orchid allergy. Archives of dermatology. 1984 Sep; 120(9):1206-8. doi: . [PMID: 6476858]
S S Handa, A D Kinghorn, G A Cordell, N R Farnsworth. Plant anticancer agents. XXVI. Constituents of Peddiea fischeri. Journal of natural products. 1983 Mar; 46(2):248-50. doi: 10.1021/np50026a020. [PMID: 6875580]