93-03-8 (BioDeep_00000863390)

Main id: BioDeep_00000000448

 

PANOMIX_OTCML-2023


代谢物信息卡片


3,4-Dimethoxyphenylmethyl alcohol

化学式: C9H12O3 (168.0786)
中文名称: 藜芦醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=C(C=C(C=C1)CO)OC
InChI: InChI=1S/C9H12O3/c1-11-8-4-3-7(6-10)5-9(8)12-2/h3-5,10H,6H2,1-2H3

描述信息

Veratryl alcohol (3,4-Dimethoxybenzenemethanol), a secondary metabolite of some lignin degrading fungi, is commonly used nonphenolic substrate for assaying ligninolytic activity[1][2].
Veratryl alcohol (3,4-Dimethoxybenzenemethanol), a secondary metabolite of some lignin degrading fungi, is commonly used nonphenolic substrate for assaying ligninolytic activity[1][2].

同义名列表

15 个代谢物同义名

3,4-Dimethoxyphenylmethyl alcohol; Benzenemethanol, 3,4-dimethoxy-; (3,4-Dimethoxyphenyl)methanol; 3,4-Dimethoxybenzyl alcohol; Veratryl alcohol (8CI); Veratryl alcohol; EINECS 202-212-0; D133000_ALDRICH; ZINC00388569; 38700_FLUKA; ST5406387; AI3-24181; NSC 6317; 93-03-8; NSC6317



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 CAT, GAPDH, LPO, PFDN5, TYR
Peripheral membrane protein 2 CYP1B1, HSD17B6
Endosome membrane 1 ATP8A2
Endoplasmic reticulum membrane 2 CANX, CYP1B1
Mitochondrion membrane 1 CANX
Nucleus 5 GAPDH, MPO, PFDN5, SP4, TGM2
cytosol 6 ACOX1, CAT, GAPDH, PFDN5, SP4, TGM2
mitochondrial membrane 1 CANX
nucleoplasm 5 ATP8A2, CD2, MPO, SP2, SP4
Cell membrane 3 ATP8A2, CD2, TGM2
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 1 ATP8A2
Golgi apparatus membrane 2 ATP8A2, POMGNT1
cell surface 2 CD2, TPO
Golgi apparatus 3 ATP8A2, CD2, POMGNT1
Golgi membrane 2 ATP8A2, POMGNT1
Cytoplasm, cytosol 2 GAPDH, TGM2
Lysosome 2 MPO, TYR
Presynapse 1 CANX
plasma membrane 6 ATP8A2, CD2, GAPDH, LIPI, TGM2, TPO
Membrane 8 ACOX1, ATP8A2, CANX, CAT, CYP1B1, GAPDH, POMGNT1, TPO
basolateral plasma membrane 1 LPO
extracellular exosome 6 CANX, CAT, GAPDH, LPO, MPO, TGM2
Lumenal side 1 HSD17B6
endoplasmic reticulum 3 CANX, HSD17B6, TGM2
extracellular space 4 LIPI, LPO, MPO, TPO
perinuclear region of cytoplasm 4 GAPDH, INF2, TGM2, TYR
mitochondrion 3 CAT, CYP1B1, TGM2
protein-containing complex 2 CAT, CD2
intracellular membrane-bounded organelle 6 CAT, CYP1B1, GAPDH, HSD17B6, MPO, TYR
Microsome membrane 2 CYP1B1, HSD17B6
Single-pass type I membrane protein 4 CANX, CD2, TPO, TYR
Secreted 2 LIPI, LPO
extracellular region 5 CAT, CD2, LIPI, LPO, MPO
cytoplasmic side of plasma membrane 1 CD2
Single-pass membrane protein 1 CANX
mitochondrial matrix 1 CAT
nuclear membrane 2 CANX, GAPDH
external side of plasma membrane 1 CD2
Secreted, extracellular space, extracellular matrix 1 TGM2
microtubule cytoskeleton 1 GAPDH
Melanosome membrane 2 CANX, TYR
cell-cell junction 1 CD2
Golgi-associated vesicle 1 TYR
Single-pass type II membrane protein 1 POMGNT1
vesicle 1 GAPDH
Cytoplasm, perinuclear region 2 GAPDH, INF2
Cytoplasm, cytoskeleton 1 GAPDH
focal adhesion 2 CAT, TGM2
extracellular matrix 1 TGM2
Peroxisome 2 ACOX1, CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 2 ACOX1, CAT
peroxisomal membrane 2 ACOX1, CAT
collagen-containing extracellular matrix 1 TGM2
secretory granule 1 MPO
chromatin 3 SP2, SP4, TGM2
cell projection 1 ATP8A2
Chromosome 1 TGM2
cytoskeleton 1 GAPDH
actin filament 1 INF2
[Isoform 2]: Cell membrane 1 LIPI
Endomembrane system 1 ATP8A2
Lipid droplet 1 GAPDH
mitochondria-associated endoplasmic reticulum membrane contact site 1 CANX
Melanosome 1 TYR
intermediate filament cytoskeleton 1 PFDN5
azurophil granule 1 MPO
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum quality control compartment 1 CANX
endoplasmic reticulum lumen 1 CANX
Photoreceptor inner segment membrane 1 ATP8A2
azurophil granule lumen 1 MPO
phagocytic vesicle lumen 1 MPO
ribonucleoprotein complex 1 GAPDH
prefoldin complex 1 PFDN5
lumenal side of endoplasmic reticulum membrane 1 CANX
[Isoform 1]: Cell membrane 1 LIPI
nucleosome 1 TGM2
photoreceptor outer segment membrane 1 ATP8A2
phospholipid-translocating ATPase complex 1 ATP8A2
GAIT complex 1 GAPDH
catalase complex 1 CAT
[Isoform 2]: Cytoplasm, perinuclear region 1 TGM2


文献列表

  • Haichuan Zhang, Yang Liu, Shiyu Fu, Yulin Deng. Selective hydrodeoxygenation of lignin model compound (3,4-dimethoxybenzyl alcohol) by Pd/CNX catalyst. International journal of biological macromolecules. 2021 Feb; 169(?):274-281. doi: 10.1016/j.ijbiomac.2020.12.092. [PMID: 33345971]
  • Carl J Houtman, Eranda Maligaspe, Christopher G Hunt, Elena Fernández-Fueyo, Angel T Martínez, Kenneth E Hammel. Fungal lignin peroxidase does not produce the veratryl alcohol cation radical as a diffusible ligninolytic oxidant. The Journal of biological chemistry. 2018 03; 293(13):4702-4712. doi: 10.1074/jbc.ra117.001153. [PMID: 29462790]
  • Paula Nousiainen, Jussi Kontro, Helmiina Manner, Annele Hatakka, Jussi Sipilä. Phenolic mediators enhance the manganese peroxidase catalyzed oxidation of recalcitrant lignin model compounds and synthetic lignin. Fungal genetics and biology : FG & B. 2014 Nov; 72(?):137-149. doi: 10.1016/j.fgb.2014.07.008. [PMID: 25108071]
  • Le Thanh Mai Pham, Yong Hwan Kim. Accelerated degradation of lignin by lignin peroxidase isozyme H8 (LiPH8) from Phanerochaete chrysosporium with engineered 4-O-methyltransferase from Clarkia breweri. Enzyme and microbial technology. 2014 Nov; 66(?):74-9. doi: 10.1016/j.enzmictec.2014.08.011. [PMID: 25248703]
  • Christopher G Hunt, Carl J Houtman, Don C Jones, Peter Kitin, Premsagar Korripally, Kenneth E Hammel. Spatial mapping of extracellular oxidant production by a white rot basidiomycete on wood reveals details of ligninolytic mechanism. Environmental microbiology. 2013 Mar; 15(3):956-66. doi: 10.1111/1462-2920.12039. [PMID: 23206186]
  • Yuka Koike, Motonori Fukumura, Yasuaki Hirai, Yumiko Hori, Shiho Usui, Toshiyuki Atsumi, Kazuo Toriizuka. Novel phenolic glycosides, adenophorasides A-E, from Adenophora roots. Journal of natural medicines. 2010 Jul; 64(3):245-51. doi: 10.1007/s11418-010-0398-5. [PMID: 20229365]
  • F Vinale, E L Ghisalberti, G Flematti, R Marra, M Lorito, K Sivasithamparam. Secondary metabolites produced by a root-inhabiting sterile fungus antagonistic towards pathogenic fungi. Letters in applied microbiology. 2010 Apr; 50(4):380-5. doi: 10.1111/j.1472-765x.2010.02803.x. [PMID: 20156309]
  • Yuta Miki, María Morales, Francisco J Ruiz-Dueñas, María Jesús Martínez, Hiroyuki Wariishi, Angel T Martínez. Escherichia coli expression and in vitro activation of a unique ligninolytic peroxidase that has a catalytic tyrosine residue. Protein expression and purification. 2009 Dec; 68(2):208-14. doi: 10.1016/j.pep.2009.06.003. [PMID: 19505579]
  • I G Gazarian, L M Lagrimini, S J George, R N Thorneley. Anionic tobacco peroxidase is active at extremely low pH: veratryl alcohol oxidation with a pH optimum of 1.8. The Biochemical journal. 1996 Dec; 320 ( Pt 2)(?):369-72. doi: 10.1042/bj3200369. [PMID: 8973542]
  • I Frías, J M Trujillo, J Romero, J Hernandez, J A Pérez. Lignan models as inhibitors of Phanerochaete chrysosporium lignin peroxidase. Biochimie. 1995; 77(9):707-12. doi: 10.1016/0300-9084(96)88186-7. [PMID: 8789460]
  • P J Harvey, R Floris, T Lundell, J M Palmer, H E Schoemaker, R Wever. Catalytic mechanisms and regulation of lignin peroxidase. Biochemical Society transactions. 1992 May; 20(2):345-9. doi: 10.1042/bst0200345. [PMID: 1397627]