Axsain (BioDeep_00000861554)

Main id: BioDeep_00000000112

 

PANOMIX_OTCML-2023


代谢物信息卡片


(6E)-N-{[4-hydroxy-3-(methyloxy)phenyl]methyl}-8-methylnon-6-enamide

化学式: C18H27NO3 (305.1990832)
中文名称: TRANS-辣椒素-D3, 天然辣椒碱
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)/C=C/CCCCC(NCC1=CC=C(O)C(OC)=C1)=O
InChI: InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+

描述信息

M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AB - Capsaicin and similar agents
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
N - Nervous system > N01 - Anesthetics > N01B - Anesthetics, local
D003879 - Dermatologic Agents > D000982 - Antipruritics
Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects[1][2].
Capsaicin ((E)-Capsaicin), an active component of chili peppers, is a TRPV1 agonist. Capsaicin has pain relief, antioxidant, anti-inflammatory, neuroprotection and anti-cancer effects[1][2].
Capsaicinoid is a mixture of Capsaicin and Dihydrocapsaicin. Capsaicinoid is an capsaicin receptor (TRPV1) agonist[1][2].
Capsaicinoid is a mixture of Capsaicin and Dihydrocapsaicin. Capsaicinoid is an capsaicin receptor (TRPV1) agonist[1][2].

同义名列表

122 个代谢物同义名

(6E)-N-{[4-hydroxy-3-(methyloxy)phenyl]methyl}-8-methylnon-6-enamide; 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (6E)-; 6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-, (E)-; 6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (E)-; (E)-N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide; N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide, (E)-; (E)-N-((4-Hydroxy-3-methoxyphenyl)-methyl)-8-methyl-6-nonenamide; [(E)-N-(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; (E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; N-[(4-hydroxy-3-methoxy-phenyl)methyl]-8-methyl-non-6-enamide; N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide; N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-trans-6-enamide; (E)-N-(4-hydroxy-3-methoxy-benzyl)-8-methyl-non-6-enamide; (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide; N-(4-hydroxy-3-methoxy-benzyl)-8-methyl-non-6-enamide; N-[(4-hydroxy-3-methoxy-phenyl)methyl]nonanamide; 6-Nonenamide, 8-methyl-N-vanillyl-, (E)- (8CI); 4-13-00-02588 (Beilstein Handbook Reference); 6-Nonenamide, 8-methyl-N-vanillyl-, (E)-; 8-Methyl-N-vanillyl-trans-6-nonenamide; trans-8-Methyl-N-vanillyl-6-nonenamide; 8-Methyl-N-vanillyl-6-nonenamide, (E)-; (E)-8-Methyl-N-vanillyl-6-nonenamide; Capsaicin (in oleoresin of capsicum); Capsaicin [in oleoresin of capsicum]; EPA Pesticide Chemical Code 070701; Isodecenoic acid vanillylamide; SDCCGMLS-0066678.P001; depletes Substance P; Capsaicin (JAN\USP); Prestwick3_000879; Prestwick2_000879; Prestwick1_000879; Prestwick0_000879; nchembio862-comp2; EINECS 206-969-8; Spectrum4_001739; Spectrum2_000770; Capsaicin [USAN]; Spectrum3_001449; UPCMLD-DP092:002; Spectrum5_000538; UPCMLD-DP092:001; NCGC00090853-07; NCGC00090853-02; trans-Capsaicin; NCGC00090853-06; Caswell No. 158; NCGC00090853-08; Spectrum_000303; NCGC00090853-03; NCGC00090853-01; SPECTRUM1501128; 360376_ALDRICH; BSPBio_001548; KBioGR_002158; KBioSS_000268; BPBio1_001053; KBioSS_000783; KBioGR_000268; BSPBio_000957; DivK1c_000354; BSPBio_002917; Prestwick_204; (E)-Capsaicin; FEMA No. 3404; MEGxp0_001448; KBio2_003351; KBio3_002417; KBio1_000354; KBio2_002836; SPBio_002878; SPBio_000820; KBio2_000783; Capsaicin-d3; KBio2_005919; KBio2_005404; ZOSTRIX (TN); KBio2_000268; KBio3_000536; ZINC01530575; NINDS_000354; KBio3_000535; Bio1_000957; Bio2_000268; BRN 2816484; M2028_SIGMA; Bio1_000468; 21750_FLUKA; IDI1_000354; 12084_FLUKA; Bio1_001446; SMP2_000337; IDI1_034018; Bio2_000748; E-CAPSAICIN; 21748_FLUKA; neurotoxic; Zostrix HP; Capsaicine; CHEBI:3374; CCRIS 1588; NCI-C56564; Transacin; NSC 56353; Styptysat; Capsaicin; NGX-7325; NGX-4010; 404-86-4; NSC56353; NGX-1998; ST057183; HSDB 954; NGX-3781; TQ-1018; Zostrix; C06866; D00250; Axsain; MR3H3; Capsaicinoid



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(2)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • V V Sathibabu Uddandrao, Seshathri Eraniappan, Asokan Balakrishnan Ramajayam, Sengottuvelu Singaravel, Anitha Roy, Brahma Naidu Parim, Chandrasekaran Ponnusamy, Saravanan Ganapathy, Ponmurugan Ponnusamy, Vadivukkarasi Sasikumar. Hydroxycitric acid and capsaicin combination alleviates obesity-induced testicular apoptosis, oxidative stress and inflammation. Systems biology in reproductive medicine. 2024 Dec; 70(1):20-37. doi: 10.1080/19396368.2024.2306403. [PMID: 38323592]
  • Xueying Bai, Qin Zhang, Xiatao Zhou, Jingyu Yao, Peng Wan, De-Wei Chen. Use of egg yolk phospholipids to improve the thermal-oxidative stability of fatty acids, capsaicinoids and carotenoids in chili oil. Food chemistry. 2024 Sep; 451(?):139423. doi: 10.1016/j.foodchem.2024.139423. [PMID: 38677135]
  • Christina Vakh, Zarina Mallabaeva, Marek Tobiszewski. Smartphone-based digital image colorimetry for the determination of total capsaicinoid content in chili pepper extracts. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2024 Jul; 315(?):124238. doi: 10.1016/j.saa.2024.124238. [PMID: 38593543]
  • Zhuxian Wang, Hongkai Chen, Tao Liang, Yi Hu, Yaqi Xue, Yufan Wu, Quanfu Zeng, Yixin Zheng, Yinglin Guo, Zeying Zheng, Dan Zhai, Peiyi Liang, Chunyan Shen, Cuiping Jiang, Li Liu, Qun Shen, Hongxia Zhu, Qiang Liu. The implications of lipid mobility, drug-enhancers (surfactants)-skin interaction, and TRPV1 activation on licorice flavonoid permeability. Drug delivery and translational research. 2024 Jun; 14(6):1582-1600. doi: 10.1007/s13346-023-01473-x. [PMID: 37980702]
  • Xiao-Lu Jie, Zhe-Ren Tong, Xin-Yue Xu, Jia-Hui Wu, Xing-Liang Jiang, Yi Tao, Pei-Shi Feng, Jin Yu, Ji-Ping Lan, Ping Wang. Mechanic study based on untargeted metabolomics of Pi-pa-run-fei-tang on pepper combined with ammonia induced chronic cough model mice. Journal of ethnopharmacology. 2024 May; 326(?):117905. doi: 10.1016/j.jep.2024.117905. [PMID: 38364934]
  • Weikai Chen, Xiangfeng Wang, Jie Sun, Xinrui Wang, Zhangsheng Zhu, Dilay Hazal Ayhan, Shu Yi, Ming Yan, Lili Zhang, Tan Meng, Yu Mu, Jun Li, Dian Meng, Jianxin Bian, Ke Wang, Lu Wang, Shaoying Chen, Ruidong Chen, Jingyun Jin, Bosheng Li, Xingping Zhang, Xing Wang Deng, Hang He, Li Guo. Two telomere-to-telomere gapless genomes reveal insights into Capsicum evolution and capsaicinoid biosynthesis. Nature communications. 2024 May; 15(1):4295. doi: 10.1038/s41467-024-48643-0. [PMID: 38769327]
  • Yifei Wu, Xiaochuan Wang, Jiayu Zhang, Sha Du, Zhiqiong Wang, Jinrong Li, Wenhe Zhang, Jie Xiang, Renfu Li, Jing Liu, Xin Bi. Capsaicin combined with stem cells improved mitochondrial dysfunction in PIG3V cells, an immortalized human vitiligo melanocyte cell line, by inhibiting the HSP70/TLR4/mTOR/FAK signaling axis. Molecular biology reports. 2024 May; 51(1):650. doi: 10.1007/s11033-024-09592-5. [PMID: 38734811]
  • Thaila Kawane Euflazio Maximiano, Jessica Aparecida Carneiro, Victor Fattori, Waldiceu A Verri. TRPV1: Receptor structure, activation, modulation and role in neuro-immune interactions and pain. Cell calcium. 2024 May; 119(?):102870. doi: 10.1016/j.ceca.2024.102870. [PMID: 38531262]
  • Matthew E Poynter, Madeleine M Mank, Jennifer L Ather. Obesity-associated inflammatory macrophage polarization is inhibited by capsaicin and phytolignans. American journal of physiology. Regulatory, integrative and comparative physiology. 2024 May; 326(5):R370-R382. doi: 10.1152/ajpregu.00161.2023. [PMID: 38436058]
  • Melina Keller, Stefan Mergler, Aruna Li, Ingrid Zahn, Friedrich Paulsen, Fabian Garreis. Thermosensitive TRP Channels Are Functionally Expressed and Influence the Lipogenesis in Human Meibomian Gland Cells. International journal of molecular sciences. 2024 Apr; 25(7):. doi: 10.3390/ijms25074043. [PMID: 38612853]
  • Renata de Souza Sampaio, Anita Oliveira Brito Pereira Bezerra Martins, Lucas Yure Santos da Silva, Dra Renata Torres Pessoa, Jaime Ribeiro-Filho, Gyllyandeson de Araújo Delmondes, Cícero Francisco Bezerra Felipe, Irwin Rose Alencar de Menezes, Marta Regina Kerntopf. Topical Antiedematogenic Activity of the Essential Oil of Psidium brownianum Mart. (OEPB) in Murine Ear Edema Models. Chemistry & biodiversity. 2024 Apr; 21(4):e202400187. doi: 10.1002/cbdv.202400187. [PMID: 38429232]
  • Qingyu Qin, Bing Gao, Xinyan Zhang, Lujia Han, Swee Leong Sing, Xian Liu. Effects of capsaicin loads on the properties of capsicum leaf protein-based nanocellulose composite films. International journal of biological macromolecules. 2024 Apr; 265(Pt 2):130904. doi: 10.1016/j.ijbiomac.2024.130904. [PMID: 38553392]
  • Sandra Vaz Soares Martins, Angélica Cristina Coelho Britto, Marcos Gomide Tozzati, Lizandra Guidi Magalhães, Márcio Luis Andrade E Silva, Ana Helena Januário, Patrícia Mendonça Pauletti, Antônio Eduardo Miller Crotti, Amanda Vargas Dos Passos, Ester Gonçalves de Jesus, Amanda Diniz Peixoto, Gabriela Dos Santos Medeiros, Mário F C Santos, Wilson Roberto Cunha. Evaluation of the in vitro schistosomicidal, leishmanicidal, and trypanocidal activities of the capsaicin metabolite, Capsicum frutescens, and Capsicum baccatum extracts and of their analysis of the main constituents by HPLC/UV and CG/MS. Natural product research. 2024 Feb; 38(4):679-684. doi: 10.1080/14786419.2023.2187793. [PMID: 36905171]
  • Elham Karimi-Sales, Gisou Mohaddes, Mohammad Reza Alipour. Hepatoprotection of capsaicin in alcoholic and non-alcoholic fatty liver diseases. Archives of physiology and biochemistry. 2024 Feb; 130(1):38-48. doi: 10.1080/13813455.2021.1962913. [PMID: 34396890]
  • Wandresa Francelino Pereira, Luiz Everson da Silva, Wanderlei do Amaral, Ricardo Andrade Rebelo, Blasco Quefi, Antonio Wlisses da Silva, Emmanuel Silva Marinho, Antonio Linkoln Alves Borges Leal, Francisco Ferdinando Mesquita Cajazeiras, Jéssica Bezerra Maciel, Hortência Ribeiro Liberato, Maria Kueirislene Amâncio Ferreira, Jesyka Macêdo Guedes, Jane Eire Silva Alencar de Menezes, Alexandre Magno Rodrigues Teixeira, Helcio Silva Dos Santos. Essential oils from the genus Piper promote antinociception by modulating TRP channels and anti-inflammatory effects in adult Zebrafish. Chemistry & biodiversity. 2024 Jan; ?(?):e202301807. doi: 10.1002/cbdv.202301807. [PMID: 38284478]
  • Beatriz A Luz-Martínez, Dailenys Marrero-Morfa, Francisco J Luna-Vázquez, Alejandra Rojas-Molina, Cesar Ibarra-Alvarado. Affinin, isolated from Heliopsis longipes, induces an antihypertensive effect that involves CB1 cannabinoid receptors and TRPA1 and TRPV1 channels activation. Planta medica. 2024 Jan; ?(?):. doi: 10.1055/a-2244-8855. [PMID: 38219731]
  • Ryota Nakaniwa, Yuki Misawa, Saika Nakasato, Kaori Sano, Yoshiyuki Tanaka, Sachie Nakatani, Kenji Kobata. Biochemical Aspects of Putative Aminotransferase Responsible for Converting Vanillin to Vanillylamine in the Capsaicinoid Biosynthesis Pathway in Capsicum Plants. Journal of agricultural and food chemistry. 2024 Jan; 72(1):559-565. doi: 10.1021/acs.jafc.3c07369. [PMID: 38134368]
  • Stephanie A Bierly, Emily P Van Syoc, Mariana F Westphalen, Asha M Miles, Natalia C Gaeta, Tara L Felix, Alexander N Hristov, Erika K Ganda. Alterations of rumen and fecal microbiome in growing beef and dairy steers fed rumen-protected Capsicum oleoresin. Journal of animal science. 2024 Jan; 102(?):. doi: 10.1093/jas/skae014. [PMID: 38227811]
  • Jun-Yan He, Xiao-Yu Tu, Zi-Fei Yin, Hui Mu, Ming-Jun Luo, Xing-Yu Chen, Wei-Bin Cai, Xue Zhao, Can Peng, Fan-Fu Fang, Can Lü, Bai Li. Short-term effects of cupping and scraping therapy for chronic nonspecific low-back pain: A prospective, multicenter randomized trial. Journal of integrative medicine. 2024 Jan; 22(1):39-45. doi: 10.1016/j.joim.2024.01.004. [PMID: 38311541]
  • Rui Deng, Suyun Yu, Xingqiu Ruan, Huan Liu, Gangfan Zong, Peng Cheng, Ruizhi Tao, Wenxing Chen, Aiyun Wang, Yang Zhao, Zhonghong Wei, Yin Lu. Capsaicin orchestrates metastasis in gastric cancer via modulating expression of TRPV1 channels and driving gut microbiota disorder. Cell communication and signaling : CCS. 2023 12; 21(1):364. doi: 10.1186/s12964-023-01265-3. [PMID: 38129926]
  • Hirokazu Kusaka, Saika Nakasato, Kaori Sano, Kenji Kobata, Sho Ohno, Motoaki Doi, Yoshiyuki Tanaka. An evolutionary view of vanillylamine synthase pAMT, a key enzyme of capsaicinoid biosynthesis pathway in chili pepper. The Plant journal : for cell and molecular biology. 2023 Dec; ?(?):. doi: 10.1111/tpj.16573. [PMID: 38117481]
  • Fangfang Dou, Beiling Wu, Jiulin Chen, Te Liu, Zhihua Yu, Chuan Chen. Capsaicin inhibits A7r5 cell senescence via the mitochondrial carrier protein Slc25a12. Experimental cell research. 2023 12; 433(2):113856. doi: 10.1016/j.yexcr.2023.113856. [PMID: 37995921]
  • Vilton E L Moura E Silva, Valéria L G Panissa, Jason M Cholewa, Matheus Mesquita Vieira, Barbara M Antunes, Rayane C Moura, Priscila A Q Rossi, Marcos A P Santos, Fabio S Lira, Fabrício E Rossi. Ten weeks of Capsicum annuum L. extract supplementation did not change adipose tissue-derived hormones, appetite, body composition, and muscle strength when combined with resistance training in healthy untrained men: A clinical trial study. Nutrition research (New York, N.Y.). 2023 Dec; 122(?):33-43. doi: 10.1016/j.nutres.2023.11.010. [PMID: 38141553]
  • M Oqal, E Qnais, A Alqudah, O Gammoh. Analgesic effect of the flavonoid herbacetin in nociception animal models. European review for medical and pharmacological sciences. 2023 Dec; 27(23):11236-11248. doi: 10.26355/eurrev_202312_34563. [PMID: 38095373]
  • Ali Mohammad Pourbagher-Shahri, Fatemeh Forouzanfar. Saffron (Crocus sativus) and its constituents for pain management: A review of current evidence. Phytotherapy research : PTR. 2023 Nov; 37(11):5041-5057. doi: 10.1002/ptr.7968. [PMID: 37528638]
  • Aristodemos-Theodoros Periferakis, Argyrios Periferakis, Konstantinos Periferakis, Ana Caruntu, Ioana Anca Badarau, Ilinca Savulescu-Fiedler, Cristian Scheau, Constantin Caruntu. Antimicrobial Properties of Capsaicin: Available Data and Future Research Perspectives. Nutrients. 2023 Sep; 15(19):. doi: 10.3390/nu15194097. [PMID: 37836381]
  • Deborah Giordano, Angelo Facchiano, Paola Minasi, Nunzio D'Agostino, Mario Parisi, Virginia Carbone. Phenolic Compounds and Capsaicinoids in Three Capsicum annuum Varieties: From Analytical Characterization to In Silico Hypotheses on Biological Activity. Molecules (Basel, Switzerland). 2023 Sep; 28(19):. doi: 10.3390/molecules28196772. [PMID: 37836615]
  • Sri-Arun Iamjan, Siriluk Veerasakul, Samur Thanoi, Waree Tiyaboonchai, Sutisa Nudmamud-Thanoi. A solid lipid particle formulation of long pepper extract reduces pain and astrocyte activation in a rat model of neuropathic pain. Journal of complementary & integrative medicine. 2023 Sep; ?(?):. doi: 10.1515/jcim-2023-0043. [PMID: 37712769]
  • Guangyu Wang. Thermoring-based heat activation switches in the TRPV1 biothermometer. International journal of biological macromolecules. 2023 Sep; 248(?):125915. doi: 10.1016/j.ijbiomac.2023.125915. [PMID: 37481175]
  • Ariza Gulzar, Ajaz Malik, Geetika Malik, Khursheed Hussain, Nageena Nazir, Ishfaq Aabidi, Umar Gani, Ammarah Hami, Reetika Mahajan, Shabir Bangroo, Sajad Majeed Zargar. Identification of novel SNPs in Pun1 locus for pungency in Capsicum species. Molecular biology reports. 2023 Sep; 50(9):7571-7579. doi: 10.1007/s11033-023-08691-z. [PMID: 37515708]
  • Nada Birkic, David Visentin, Željko Svedružić, Christian A Reynolds. Binding interactions of fatty acyl lipid mediators within the vanilloid pocket of TRPV1: A molecular dynamics study. Prostaglandins & other lipid mediators. 2023 Aug; 169(?):106771. doi: 10.1016/j.prostaglandins.2023.106771. [PMID: 37657597]
  • Omar M E Abdel-Salam, Gyula Mózsik. Capsaicin, The Vanilloid Receptor TRPV1 Agonist in Neuroprotection: Mechanisms Involved and Significance. Neurochemical research. 2023 Jul; ?(?):. doi: 10.1007/s11064-023-03983-z. [PMID: 37493882]
  • Liping Zhang, Dan Wu, Wei Zhang, Huangying Shu, Peixia Sun, Chuang Huang, Qin Deng, Zhiwei Wang, Shanhan Cheng. Genome-Wide Identification of WRKY Gene Family and Functional Characterization of CcWRKY25 in Capsicum chinense. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411389. [PMID: 37511147]
  • Murat Oz, Dietrich E Lorke, Frank C Howarth. Transient receptor potential vanilloid 1 (TRPV1)-independent actions of capsaicin on cellular excitability and ion transport. Medicinal research reviews. 2023 07; 43(4):1038-1067. doi: 10.1002/med.21945. [PMID: 36916676]
  • Sara Falsini, Marzia Cristiana Rosi, Elia Ravegnini, Silvia Schiff, Cristina Gonnelli, Alessio Papini, Alessandra Adessi, Silvia Urciuoli, Sandra Ristori. Nanoformulations with exopolysaccharides from cyanobacteria: enhancing the efficacy of bioactive molecules in the Mediterranean fruit fly control. Environmental science and pollution research international. 2023 Jul; 30(35):83760-83770. doi: 10.1007/s11356-023-28180-x. [PMID: 37347326]
  • Khushbu Islam, Abdul Rawoof, Ajay Kumar, John Momo, Ilyas Ahmed, Meenakshi Dubey, Nirala Ramchiary. Genetic Regulation, Environmental Cues, and Extraction Methods for Higher Yield of Secondary Metabolites in Capsicum. Journal of agricultural and food chemistry. 2023 Jun; 71(24):9213-9242. doi: 10.1021/acs.jafc.3c01901. [PMID: 37289974]
  • Rodrigo Alonso-Villegas, Rosa María González-Amaro, Claudia Yuritzi Figueroa-Hernández, Ingrid Mayanin Rodríguez-Buenfil. The Genus Capsicum: A Review of Bioactive Properties of Its Polyphenolic and Capsaicinoid Composition. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28104239. [PMID: 37241977]
  • Ayumi Sumino, Yimeng Zhao, Daichi Mukai, Takashi Sumikama, Leonardo Puppulin, Motoyuki Hattori, Mikihiro Shibata. Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel. Proceedings of the National Academy of Sciences of the United States of America. 2023 May; 120(20):e2301013120. doi: 10.1073/pnas.2301013120. [PMID: 37155841]
  • Jingxing He, Xiaolin Wu, Youfa Xie, Yi Gao, David Julian McClements, Lu Zhang, Liqiang Zou, Wei Liu. Capsaicin encapsulated in W/O/W double emulsions fabricated via ethanol-induced pectin gelling: Improvement of bioaccessibility and reduction of irritation. International journal of biological macromolecules. 2023 Apr; 235(?):123899. doi: 10.1016/j.ijbiomac.2023.123899. [PMID: 36870641]
  • Li-Dan Zhou, Yi-Na Lu, Qing Liu, Xue-Mei Shi, Jun Tian. Modulation of TRPV1 function by Citrus reticulata (tangerine) fruit extract for the treatment of sensitive skin. Journal of cosmetic dermatology. 2023 Apr; 22(4):1369-1376. doi: 10.1111/jocd.15578. [PMID: 36575892]
  • Yuan Zhao, Wenqin Wu, Xiaoqian Tang, Qi Zhang, Jin Mao, Li Yu, Peiwu Li, Zhaowei Zhang. A universal CRISPR/Cas12a-powered intelligent point-of-care testing platform for multiple small molecules in the healthcare, environment, and food. Biosensors & bioelectronics. 2023 Apr; 225(?):115102. doi: 10.1016/j.bios.2023.115102. [PMID: 36724657]
  • Jing-Xian Sun, Ke-Ying Zhu, Yu-Meng Wang, Dan-Jie Wang, Mi-Zhen Zhang, Heela Sarlus, Irene Benito-Cuesta, Xiao-Qiang Zhao, Zao-Feng Zou, Qing-Yang Zhong, Yi Feng, Shuai Wu, Yan-Qing Wang, Robert A Harris, Jun Wang. Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function. Acta pharmacologica Sinica. 2023 Apr; 44(4):766-779. doi: 10.1038/s41401-022-01000-7. [PMID: 36229601]
  • Shuang Yu, Wei Zhang, Liping Zhang, Dan Wu, Peixia Sun, Chuang Huang, Genying Fu, Qin Deng, Zhiwei Wang, Shanhan Cheng. MYB24 Negatively Regulates the Biosynthesis of Lignin and Capsaicin by Affecting the Expression of Key Genes in the Phenylpropanoid Metabolism Pathway in Capsicum chinense. Molecules (Basel, Switzerland). 2023 Mar; 28(6):. doi: 10.3390/molecules28062644. [PMID: 36985616]
  • Mostafakamal Shams, Esra Arslan Yuksel, Guleray Agar, Melek Ekinci, Raziye Kul, Metin Turan, Ertan Yildirim. Biosynthesis of capsaicinoids in pungent peppers under salinity stress. Physiologia plantarum. 2023 Mar; ?(?):e13889. doi: 10.1111/ppl.13889. [PMID: 36905231]
  • Yasmine Radwan, Kholoud K Arafa, Monira G Ghoniem, Eida S Al-Farraj, Ibrahim M El-Sherbiny. An in-vitro quantitative investigation on the synergistic effect of capsaicin and 5-fluorouracil encapsulated into lipid nanocapsules to treat breast cancer. Drug development and industrial pharmacy. 2023 Mar; 49(3):271-280. doi: 10.1080/03639045.2023.2203252. [PMID: 37067846]
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