2-PEA (BioDeep_00000860439)

Chemicals and Drugs

代谢物信息卡片

InChI=1\C8H10O\c9-7-6-8-4-2-1-3-5-8\h1-5,9H,6-7H

化学式: C8H10O (122.0732)
中文名称: 苯乙醇, 2-苯乙醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)CCO
InChI: InChI=1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2

描述信息

C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent
D000890 - Anti-Infective Agents
D010592 - Pharmaceutic Aids
D004202 - Disinfectants
2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[1]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.
2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[1]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

同义名列表

62 个代谢物同义名

InChI=1\C8H10O\c9-7-6-8-4-2-1-3-5-8\h1-5,9H,6-7H; 4-06-00-03067 (Beilstein Handbook Reference); EPA Pesticide Chemical Code 001503; beta-Fenethylalkohol [Czech]; Phenethyl alcohol (natural); .beta.-Phenylethyl alcohol; .beta.-Hydroxyethylbenzene; beta-Fenylethanol [Czech]; Phenylethyl alcohol (USP); .beta.-Phenethyl alcohol; beta-Hydroxyethylbenzene; PHENYLETHYL, B- ALCOHOL; 2-Hydroxyethylbenzene; 2-Phenylethyl alcohol; Phenyl ethyl alcohol; Benzyl ethyl alcohol; .beta.-Phenylethanol; 2-Phenethyl alcohol; Phenylethyl alcohol; beta-Phenylethanol; 1-Phenyl-2-ethanol; Ethanol, 2-phenyl-; Methanol, benzyl-; Phenethyl alcohol; 2-PHENYL-ethanol; FEMA Number 2858; Caswell No. 655C; Ethanol, phenyl-; EINECS 200-456-2; 2-Phenylethanol; NCGC00166215-01; Benzyl carbinol; W285803_ALDRICH; W285811_ALDRICH; Benzeneethanol; P13606_ALDRICH; Benzylmethanol; Benzylcarbinol; FEMA No. 2858; Phenylethanol; SMR000059156; MLS001066349; ZINC00895934; P6134_SIGMA; Phenethanol; 77861_FLUKA; BRN 1905732; .beta.-PEA; NSC 406252; NSC406252; 1321-27-3; ST5214476; HSDB 5002; AI3-00744; WLN: Q2R; 60-12-8; C05853; D00192; 2-PEA; PEL; Phenylethyl alcohol; Phenylethyl Alcohol

数据库引用编号

21 个数据库交叉引用编号

ChEBI: CHEBI:49000
KEGG: C05853
PubChem: 6054
DrugBank: DB02192
ChEMBL: CHEMBL448500
MeSH: Phenylethyl Alcohol
CAS: 19601-20-8
CAS: 1321-27-3
CAS: 60-12-8
PubChem: 8146
KNApSAcK: C00002663
PDB-CCD: PEL
3DMET: B00869
NIKKAJI: J1.924K
RefMet: Phenylethanol
medchemexpress: HY-B1290
KNApSAcK: 49000
LOTUS: LTS0012327
wikidata: Q419340
LOTUS: LTS0206341
wikidata: Q209463

分类词条

抗生素

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

173 个相关的物种来源信息

282714 - Achillea abrotanoides: 10.1016/0305-1978(92)90070-T
64042 - Actaea simplex: 10.1016/0305-1978(87)90058-5
501610 - Agathosma betulina: 10.1021/JF60201A021
43982 - Ambrosiozyma monospora: 10.1055/S-2007-969476
175730 - Amorphophallus eichleri: 10.1016/S0031-9422(97)00221-5
48027 - Anthriscus sylvestris: 10.1248/YAKUSHI1947.99.6_602
265783 - Artemisia capillaris: 10.1055/S-2005-837790
155124 - Aspalathus linearis: 10.1021/JF00062A024
5061 - Aspergillus niger: 10.1016/0031-9422(88)80021-9
385370 - Aster scaber: 10.1021/JF00034A033
28974 - Averrhoa carambola: 10.1021/JF00062A009
124943 - Azadirachta indica: 10.1016/0010-7824(90)90054-Y
1392 - Bacillus anthracis: 10.1038/S41598-020-66136-0
3589 - Basella alba: 10.1016/0889-1575(91)90017-Z
41492 - Bellis perennis: 10.1016/0031-9422(95)00183-8
42337 - Bidens pilosa: 10.1002/JCCS.200000152
3707 - Brassica juncea: 10.1016/0031-9422(88)83085-1
3708 - Brassica napus: 10.1016/0031-9422(88)83085-1
3710 - Brassica nigra: 10.1016/0031-9422(88)83085-1
3711 - Brassica rapa: 10.1016/0031-9422(88)83085-1
4442 - Camellia sinensis:
13393 - Cananga odorata: 10.1021/JF00069A028
5482 - Candida tropicalis: 10.1007/BF00988116
114816 - Castanopsis cuspidata: 10.1021/JF60224A025
260595 - Cedronella canariensis: 10.1016/0031-9422(95)00241-X
50282 - Centaurea benedicta: 10.1055/S-0028-1099484
38033 - Chaetomium globosum:
114280 - Cichorium endivia: 10.1021/JF00068A014
128608 - Cinnamomum verum: 10.1021/JF60218A031
3654 - Citrullus lanatus: 10.1271/BBB1961.49.3145
558547 - Citrus deliciosa: 10.1016/J.PHYTOCHEM.2009.07.031
170989 - Citrus hystrix: 10.1016/J.PHYTOCHEM.2009.07.031
85571 - Citrus reticulata: 10.1016/J.PHYTOCHEM.2009.07.031
78388 - Coniothyrium: 10.1021/NP980341E
4265 - Cynara cardunculus: 10.1016/S0031-9422(82)85033-4
328070 - Dactylanthus taylorii: 10.1016/0031-9422(95)00403-T
329675 - Daphne odora: 10.1271/BBB1961.47.483
2715869 - Daphne papyracea: 10.1271/BBB1961.47.483
492000 - Decalepis hamiltonii: 10.1002/1099-1026(200101/02)16:1<27::AID-FFJ937>3.0.CO;2-F
33171 - Eremothecium ashbyi: 10.1007/BF00598377
33169 - Eremothecium gossypii: 10.1007/BF00630334
1078594 - Erucaria microcarpa: 10.1002/(SICI)1099-1573(199906)13:4<329::AID-PTR458>3.0.CO;2-U
3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
263 - Francisella tularensis: 10.1038/S41598-020-66136-0
169388 - Fusarium solani: 10.1016/0031-9422(88)80051-7
373155 - Gaillardia aestivalis: 10.1016/S0031-9422(00)95216-6
114476 - Gardenia jasminoides: 10.1271/BBB.57.1101
49827 - Glycyrrhiza glabra:
201509 - Gmelina arborea: -
63704 - Gonioctena viminalis: 10.1007/BF01940454
3635 - Gossypium hirsutum: 10.1021/JF60200A011
226899 - Grosmannia clavigera: 10.1139/V86-149
671128 - Gymnodinium nagasakiense: 10.1016/0031-9422(92)80160-G
264418 - Hesperis matronalis:
39324 - Hyssopus officinalis: 10.1002/FFJ.2730060109
483693 - Inula racemosa: 10.1016/S0031-9422(00)83760-7
55982 - Ips cembrae: 10.1007/S000490050010
85216 - Jasminum polyanthum: 10.1271/BBB.57.1101
660624 - Jasminum sambac: 10.1271/BBB.57.1101
16719 - Juglans nigra:
225107 - Karenia mikimotoi: 10.1016/0031-9422(92)80160-G
39333 - Lavandula stoechas: 10.1016/0305-1978(96)00023-3
105884 - Lonicera japonica: 10.1021/JF950275B
2849048 - Lucensosergia lucens: 10.1080/00021369.1984.10866348
3750 - Malus domestica: 10.1021/JF00025A025
283210 - Malus pumila: 10.1021/JF00025A025
3879 - Medicago sativa: 10.1016/S0031-9422(97)00119-2
39338 - Melissa officinalis:
119949 - Myrtus communis:
4432 - Nelumbo nucifera: -
118694 - Nicotiana bonariensis: 10.1016/J.PHYTOCHEM.2006.05.038
118700 - Nicotiana langsdorffii: 10.1016/J.PHYTOCHEM.2006.05.038
145953 - Ophrys sphegodes: 10.1016/S0031-9422(00)81276-5
49558 - Osmorhiza aristata: 10.1248/YAKUSHI1947.99.11_1116
40698 - Paeonia anomala: 10.1007/BF00629664
35924 - Paeonia lactiflora:
45171 - Paeonia suffruticosa: 10.1080/00021369.1983.10866058
159425 - Passiflora incarnata: 10.1080/10412905.1992.9698081
125157 - Peristeria elata: 10.1080/10412905.1992.9698106
146781 - Phallus impudicus:
1807033 - Phomopsis velata: 10.1016/S0031-9422(00)83157-X
222877 - Phyla nodiflora: 10.1021/NP50039A037
5791 - Physarum polycephalum: 10.1248/CPB.32.797
4926 - Pichia membranifaciens: 10.1021/NP070605+
33090 - Plants: -
204156 - Platostoma africanum: 10.1055/S-2006-962093
62097 - Plumeria rubra:
174549 - Polygala senega: 10.1002/FFJ.2730100408
73824 - Populus balsamifera: 10.1515/ZNC-1989-5-603
1616482 - Populus candicans: 10.1515/ZNC-1989-5-603
60009 - Populus ciliata: 10.1016/0031-9422(91)85033-V
36596 - Prunus armeniaca: 10.1021/JF00004A032
140311 - Prunus cerasus: 10.1016/0031-9422(90)85126-Z
3758 - Prunus domestica: 10.1021/JF00004A032
3755 - Prunus dulcis: 10.1021/JF60228A025
97307 - Prunus padus: 10.1080/10412905.1990.9697889
3760 - Prunus persica: 10.1021/JF00004A032
313948 - Rhanterium epapposum: 10.1002/FFJ.2730020106
203015 - Rhodiola rosea: 10.1016/S0031-9422(02)00004-3
35938 - Robinia pseudoacacia: 10.1039/AN9285300411
74632 - Rosa gallica:
39367 - Salvia rosmarinus: 10.3390/MOLECULES21111576
4463 - Sauromatum venosum: 10.1016/S0031-9422(00)94756-3
200489 - Saussurea involucrata: 10.1080/10412905.1992.9698080
65409 - Scutellaria baicalensis: 10.1271/BBB1961.51.1449
589641 - Sergia lucens: 10.1080/00021369.1984.10866348
3728 - Sinapis alba: 10.1016/J.PHYTOCHEM.2006.12.009
4081 - Solanum lycopersicum: 10.1021/JF00014A016
265416 - Solanum stuckertii: 10.1080/10412905.1997.9700728
53737 - Sphagneticola trilobata: 10.1002/FFJ.3227
67295 - Streptomyces fimicarius: 10.1155/2018/4823126
137129 - Swertia japonica: 10.1246/BCSJ.56.3477
547782 - Symphyotrichum undulatum: 10.1021/JF00034A033
334483 - Syzygium jambos: 10.1080/10412905.1991.9697916
127999 - Tanacetum parthenium: 10.1007/S004030050433
3641 - Theobroma cacao: 10.1021/JF60160A011
57577 - Trifolium pratense: 10.1021/JF00122A019
4565 - Triticum aestivum: 10.1021/JF0204755
118778 - Tussilago farfara: 10.1248/YAKUSHI1947.112.8_571
13750 - Vaccinium macrocarpon: 10.3891/ACTA.CHEM.SCAND.21-2076
180772 - Vaccinium vitis-idaea: 10.3891/ACTA.CHEM.SCAND.21-0945
205076 - Vachellia rigidula: 10.1021/JF00120A008
50172 - Viscum articulatum: 10.1248/CPB.52.858
103349 - Vitis rotundifolia:
29760 - Vitis vinifera:
4577 - Zea mays: 10.1021/JF60220A012
136225 - Zingiber mioga: 10.1271/BBB1961.55.1655
4956 - Zygosaccharomyces rouxii: 10.1271/BBB1961.54.273
219868 - 丁香: -
44586 - 三七: -
4609 - 三棱: -
58046 - 侧柏叶: -
115666 - 八角莲: -
83936 - 凌霄花: -
33090 - 北刘寄奴: -
3440 - 升麻: -
396367 - 半枝莲: -
33090 - 四季青: -
33090 - 女贞子: -
33090 - 威灵仙: -
33090 - 密蒙花: -
33090 - 山茱萸: -
33090 - 巴戟天: -
33090 - 木蝴蝶: -
33090 - 枇杷叶: -
13428 - 桂枝: -
3498 - 桑叶: -
33090 - 梅花: -
33090 - 款冬花: -
33090 - 沙棘: -
33090 - 洋金花: -
33090 - 灯心草: -
4217 - 牛蒡子: -
33090 - 玫瑰花: -
33090 - 瞿麦: -
33090 - 矮地茶: -
33090 - 紫花地丁: -
33090 - 肉桂: -
33090 - 芫花: -
33090 - 苦丁茶: -
33090 - 荆芥: -
33090 - 荔枝核: -
33090 - 葎草: -
33090 - 葛花: -
33090 - 蚕沙: -
33090 - 西河柳: -
569774 - 金线莲: -
33090 - 金银花: -
33090 - 钩藤: -
3311 - 银杏叶: -
33090 - 零陵香: -
33090 - 鸡屎藤: -
33090 - 黄芩: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表
Cytoplasm	10	ADH5, AXIN2, CAT, DBH, HMGB1, PKM, PMP2, PTGS2, TYR, XDH
Peripheral membrane protein	2	HMGB1, PTGS2
Endoplasmic reticulum membrane	1	PTGS2
Nucleus	8	ATF1, AXIN2, FOS, HMGB1, PDC, PKM, PMP2, POLA1
cytosol	11	ADH5, ADH6, AXIN2, CAT, FOS, LIPE, PDC, PKM, PMP2, POLA1, XDH
centrosome	1	AXIN2
nucleoplasm	4	ATF1, FOS, HMGB1, POLA1
RNA polymerase II transcription regulator complex	2	ATF1, FOS
Cell membrane	3	HMGB1, LIPE, TRPA1
Multi-pass membrane protein	1	TRPA1
Synapse	1	DBH
cell surface	2	HMGB1, TNR
glutamatergic synapse	1	TNR
Golgi apparatus	1	ATRN
Cytoplasm, cytosol	3	LIPE, PDC, POLA1
Lysosome	1	TYR
endosome	1	HMGB1
plasma membrane	4	ATRN, AXIN2, HMGB1, TRPA1
Membrane	4	CAT, DBH, LIPE, TRPA1
axon	1	CCK
caveola	2	LIPE, PTGS2
extracellular exosome	6	ADH5, ADH6, ATRN, CAT, PKM, PMP2
endoplasmic reticulum	4	DBH, FOS, HMGB1, PTGS2
extracellular space	6	ATRN, CCK, DBH, HMGB1, TNR, XDH
perinuclear region of cytoplasm	1	TYR
Schaffer collateral - CA1 synapse	1	TNR
mitochondrion	3	ADH5, CAT, PKM
protein-containing complex	2	CAT, PTGS2
intracellular membrane-bounded organelle	3	CAT, DBH, TYR
Microsome membrane	1	PTGS2
Single-pass type I membrane protein	2	ATRN, TYR
Secreted	3	CCK, DBH, HMGB1
extracellular region	6	CAT, CCK, DBH, HMGB1, PKM, TNR
[Isoform 2]: Secreted	1	ATRN
mitochondrial matrix	1	CAT
Extracellular side	1	HMGB1
centriolar satellite	1	DBH
photoreceptor inner segment	1	PDC
photoreceptor outer segment	1	PDC
Extracellular vesicle	1	PKM
Secreted, extracellular space, extracellular matrix	1	TNR
beta-catenin destruction complex	1	AXIN2
nucleolus	1	POLA1
Melanosome membrane	1	TYR
Golgi-associated vesicle	1	TYR
Single-pass type II membrane protein	1	DBH
vesicle	1	PKM
Membrane raft	1	TNR
focal adhesion	1	CAT
Peroxisome	2	CAT, XDH
sarcoplasmic reticulum	1	XDH
Peroxisome matrix	1	CAT
peroxisomal matrix	1	CAT
peroxisomal membrane	1	CAT
collagen-containing extracellular matrix	2	PKM, TNR
Nucleus inner membrane	1	PTGS2
Nucleus outer membrane	1	PTGS2
nuclear inner membrane	1	PTGS2
nuclear outer membrane	1	PTGS2
neuron projection	1	PTGS2
cilium	1	PKM
chromatin	3	ATF1, FOS, POLA1
stereocilium bundle	1	TRPA1
Chromosome	1	HMGB1
Cell projection, cilium, photoreceptor outer segment	1	PDC
[Isoform 3]: Secreted	1	ATRN
nuclear envelope	1	POLA1
Lipid droplet	1	LIPE
Membrane, caveola	1	LIPE
Melanosome	1	TYR
myelin sheath	1	PMP2
ficolin-1-rich granule lumen	3	CAT, HMGB1, PKM
secretory granule lumen	4	CAT, DBH, HMGB1, PKM
secretory granule membrane	1	DBH
endoplasmic reticulum lumen	1	PTGS2
nuclear matrix	2	FOS, POLA1
transcription repressor complex	1	HMGB1
perineuronal net	1	TNR
endoplasmic reticulum-Golgi intermediate compartment	1	HMGB1
[Isoform 2]: Nucleus	1	PDC
protein-DNA complex	1	FOS
[Isoform 1]: Cell membrane	1	ATRN
Cytoplasmic vesicle, secretory vesicle membrane	1	DBH
Rough endoplasmic reticulum	1	PKM
condensed chromosome	1	HMGB1
transcription factor AP-1 complex	1	FOS
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen	1	DBH
chromaffin granule lumen	1	DBH
transport vesicle membrane	1	DBH
catalase complex	1	CAT
alphav-beta3 integrin-HMGB1 complex	1	HMGB1
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen	1	DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane	1	DBH
chromaffin granule membrane	1	DBH
alpha DNA polymerase:primase complex	1	POLA1
[Isoform M2]: Cytoplasm	1	PKM
[Isoform M1]: Cytoplasm	1	PKM
ATF4-CREB1 transcription factor complex	1	ATF1
ATF1-ATF4 transcription factor complex	1	ATF1
tenascin complex	1	TNR

文献列表

Ying Lu, Luyan Gao, Wenwen Zhang, Ying Zeng, Ji Hu, Kai Song. Caffeic acid phenethyl ester restores mitochondrial homeostasis against peritoneal fibrosis induced by peritoneal dialysis through the AMPK/SIRT1 pathway. Renal failure. 2024 Dec; 46(1):2350235. doi: 10.1080/0886022x.2024.2350235. [PMID: 38721924]
Vinayak Laxman Pachapur, Mariana Valdez Castillo, Rahul Saini, Satinder Kaur Brar, Yann Le Bihan. Integrated biorefinery approach for utilization of wood waste into levulinic acid and 2-Phenylethanol production under mild treatment conditions. Journal of biotechnology. 2024 Jun; 389(?):78-85. doi: 10.1016/j.jbiotec.2024.05.002. [PMID: 38718873]
Adam J Lewis, Amanda C Richards, Alejandra A Mendez, Bijaya K Dhakal, Tiffani A Jones, Jamie L Sundsbak, Danelle S Eto, Alexis A Rousek, Matthew A Mulvey. Plant phenolics inhibit focal adhesion kinase and suppress host cell invasion by uropathogenic Escherichia coli. Infection and immunity. 2024 May; 92(5):e0008024. doi: 10.1128/iai.00080-24. [PMID: 38534100]
Li Fan, Lijuan Zhao, Yangbo Zhu, Lin Li, Xueping Yang, Ping Ma, Jian Liu, Qingwei Zhao, Xiaobo Li. Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition. Food & function. 2024 May; 15(9):5103-5117. doi: 10.1039/d4fo01027b. [PMID: 38680105]
Zhanding Cui, Jing Zhang, Jinlong Wang, Jinlong Liu, Pu Sun, Jiaoyang Li, Guoxiu Li, Ying Sun, Juanbin Ying, Kun Li, Zhixun Zhao, Hong Yuan, Xingwen Bai, Xueqing Ma, Pinghua Li, Yuanfang Fu, Huifang Bao, Dong Li, Qiang Zhang, Zaixin Liu, Yimei Cao, Zengjun Lu. Caffeic acid phenethyl ester: an effective antiviral agent against porcine reproductive and Respiratory Syndrome Virus. Antiviral research. 2024 May; 225(?):105868. doi: 10.1016/j.antiviral.2024.105868. [PMID: 38490343]
Qizhen Cui, Qingqing Liu, Yutong Fan, Chenhe Wang, Yufei Li, Shuyuan Li, Jianguo Zhang, Guodong Rao. Functional differentiation of olive PLP_deC genes: insights into metabolite biosynthesis and genetic improvement at the whole-genome level. Plant cell reports. 2024 Apr; 43(5):127. doi: 10.1007/s00299-024-03212-z. [PMID: 38652203]
Daniela Gabbia, Katia Sayaf, Ilaria Zanotto, Martina Colognesi, Yahima Frion-Herrera, Maria Carrara, Francesco Paolo Russo, Sara De Martin. Tyrosol attenuates NASH features by reprogramming the hepatic immune milieu. European journal of pharmacology. 2024 Apr; 969(?):176453. doi: 10.1016/j.ejphar.2024.176453. [PMID: 38408597]
Yu Wang, Jihang Hou, Xiaoping Li, Pan Chen, Fang Chen, Yao Pan, Zeyuan Deng, Jing Li, Rong Liu, Ting Luo. Tyrosol regulates hepatic lipid metabolism in high-fat diet-induced NAFLD mice. Food & function. 2024 Apr; 15(7):3752-3764. doi: 10.1039/d3fo05345h. [PMID: 38506160]
Guosi Li, Wei Wang, Heng Guo, Shanyong Yi, Fang Wang, Shiping Huang, Nan Hu, Qilin Xu, Yongjun Zang, Bangxing Han, Xinjian Yin. Mutability landscape guided engineering of a promiscuous microbial glycosyltransferase for regioselective synthesis of salidroside and icariside D2. International journal of biological macromolecules. 2024 Apr; 263(Pt 1):130229. doi: 10.1016/j.ijbiomac.2024.130229. [PMID: 38378110]
Ágnes Jakab, Kinga Csillag, Károly Antal, Imre Boczonádi, Renátó Kovács, István Pócsi, Tamás Emri. Total transcriptome response for tyrosol exposure in Aspergillus nidulans. Fungal biology. 2024 04; 128(2):1664-1674. doi: 10.1016/j.funbio.2024.01.003. [PMID: 38575239]
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Mojtaba Baharsaadi, Maryam Hezavehei, Abdolhossein Shahverdi, Iman Halvaei. Evaluation of the effects of hydroxytyrosol on human sperm parameters during cryopreservation. Cryobiology. 2024 03; 114(?):104840. doi: 10.1016/j.cryobiol.2023.104840. [PMID: 38104853]
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Munmun Kumar Singh, Kumari Savita, Swati Singh, Divya Mishra, Poonam Rani, Debabrata Chanda, Ram Swaroop Verma. Vasorelaxant property of 2-phenyl ethyl alcohol isolated from the spent floral distillate of damask rose (Rosa damascena Mill.) and its possible mechanism. Journal of ethnopharmacology. 2023 Sep; 313(?):116603. doi: 10.1016/j.jep.2023.116603. [PMID: 37149069]
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Rosario Pastor, Cristina Bouzas, Josep A Tur. Beneficial effects of dietary supplementation with olive oil, oleic acid, or hydroxytyrosol in metabolic syndrome: Systematic review and meta-analysis. Free radical biology & medicine. 2021 08; 172(?):372-385. doi: 10.1016/j.freeradbiomed.2021.06.017. [PMID: 34153478]
Elisa Pannucci, Rocco Caracciolo, Annalisa Romani, Francesco Cacciola, Paola Dugo, Roberta Bernini, Leonardo Varvaro, Luca Santi. An hydroxytyrosol enriched extract from olive mill wastewaters exerts antioxidant activity and antimicrobial activity on Pseudomonas savastanoi pv. savastanoi and Agrobacterium tumefaciens. Natural product research. 2021 Aug; 35(16):2677-2684. doi: 10.1080/14786419.2019.1662006. [PMID: 31496275]
Halil Ibrahim Guler, Gizem Tatar, Oktay Yildiz, Ali Osman Belduz, Sevgi Kolayli. Investigation of potential inhibitor properties of ethanolic propolis extracts against ACE-II receptors for COVID-19 treatment by molecular docking study. Archives of microbiology. 2021 Aug; 203(6):3557-3564. doi: 10.1007/s00203-021-02351-1. [PMID: 33950349]
Aurélia Malapert, Emmanuelle Reboul, Olivier Dangles, Alain Thiéry, N'nabinty Sylla, Valérie Tomao. One-Step Extraction of Olive Phenols from Aqueous Solution Using β-Cyclodextrin in the Solid State, a Simple Eco-Friendly Method Providing Photochemical Stability to the Extracts. Molecules (Basel, Switzerland). 2021 Jul; 26(15):. doi: 10.3390/molecules26154463. [PMID: 34361616]
Limei Wen, Junping Hu, Jiawei Zhang, Jianhua Yang. Phenylethanol glycosides from Herba Cistanche improve the hypoxic tumor microenvironment and enhance the effects of oxaliplatin via the HIF‑1α signaling pathway. Molecular medicine reports. 2021 07; 24(1):. doi: 10.3892/mmr.2021.12156. [PMID: 34013363]
Chen Chen, Qidi Ai, Yuhui Wei. Hydroxytyrosol protects against cisplatin-induced nephrotoxicity via attenuating CKLF1 mediated inflammation, and inhibiting oxidative stress and apoptosis. International immunopharmacology. 2021 Jul; 96(?):107805. doi: 10.1016/j.intimp.2021.107805. [PMID: 34162164]
Camila Macaúbas-Silva, Maysa D G Félix, Ana Karoline S de Aquino, Paulo G Pereira-Júnior, Emmily Vieira de O Brito, Abrahão A de Oliveira-Filho, John O Igoli, David G Watson, Yanna C F Teles. Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw. Natural product research. 2021 Jul; 35(14):2424-2428. doi: 10.1080/14786419.2019.1672683. [PMID: 31581838]
Vipul Kumar, Jaspreet Kaur Dhanjal, Sunil C Kaul, Renu Wadhwa, Durai Sundar. Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity. Journal of biomolecular structure & dynamics. 2021 07; 39(11):3842-3854. doi: 10.1080/07391102.2020.1772108. [PMID: 32431217]
Umut Yiğit, Fatma Yeşim Kırzıoğlu, Özlem Özmen, Abdülhadi Cihangir Uğuz. Protective effects of caffeic acid phenethyl ester on the heart in experimental periodontitis against oxidative stress in rats. Dental and medical problems. 2021 Jul; 58(3):335-341. doi: 10.17219/dmp/132388. [PMID: 34597478]
Zaid Badra, Sebastian Larsson Herrera, Luca Cappellin, Franco Biasioli, Teun Dekker, Sergio Angeli, Marco Tasin. Species-Specific Induction of Plant Volatiles by Two Aphid Species in Apple: Real Time Measurement of Plant Emission and Attraction of Lacewings in the Wind Tunnel. Journal of chemical ecology. 2021 Jul; 47(7):653-663. doi: 10.1007/s10886-021-01288-5. [PMID: 34196858]
Jia Liu, Zengyuan Liu, Lili Wang, Hao He, Hailong Mu, Wenjing Sun, Yu Zhou, Yingqiu Liu, Wuren Ma, Weimin Zhang, Mingzhe Fu, Yunpeng Fan, Xiaoping Song. Bioactivity-guided isolation of immunomodulatory compounds from the fruits of Ligustrum lucidum. Journal of ethnopharmacology. 2021 Jun; 274(?):114079. doi: 10.1016/j.jep.2021.114079. [PMID: 33798661]
Sebastià Galmés, Bàrbara Reynés, Mariona Palou, Andreu Palou-March, Andreu Palou. Absorption, Distribution, Metabolism, and Excretion of the Main Olive Tree Phenols and Polyphenols: A Literature Review. Journal of agricultural and food chemistry. 2021 May; 69(18):5281-5296. doi: 10.1021/acs.jafc.1c00737. [PMID: 33908772]
Camila G Dossi, Romina G Vargas, Rodrigo Valenzuela, Luis A Videla. Beneficial effects of natural compounds on experimental liver ischemia-reperfusion injury. Food & function. 2021 May; 12(9):3787-3798. doi: 10.1039/d1fo00289a. [PMID: 33977997]
Mingzhe Li, Baoan Ning, Tianhui Wang. The mechanism and prevention of mitochondrial injury after exercise. Journal of physiology and biochemistry. 2021 May; 77(2):215-225. doi: 10.1007/s13105-021-00802-3. [PMID: 33650090]
Wei Gao, Shengdao Zheng, Eunson Hwang, Tae-Hoo Yi, Yu-Shuai Wang. Effects of phenylethanol glycosides from Orobanche cernua Loefling on UVB-Induced skin photodamage: a comparative study. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2021 May; 20(5):599-614. doi: 10.1007/s43630-021-00038-6. [PMID: 33909279]
Emanuele Mauri, Manuele Gori, Sara Maria Giannitelli, Andrea Zancla, Pamela Mozetic, Franca Abbruzzese, Nicolò Merendino, Giuseppe Gigli, Filippo Rossi, Marcella Trombetta, Alberto Rainer. Nano-encapsulation of hydroxytyrosol into formulated nanogels improves therapeutic effects against hepatic steatosis: An in vitro study. Materials science & engineering. C, Materials for biological applications. 2021 May; 124(?):112080. doi: 10.1016/j.msec.2021.112080. [PMID: 33947572]
Mehmet Gül, Serkan Dündar, Gökhan Artaş, Akın Yiğin, Abdulsamet Tanık, Mehmet Emrah Polat, Erhan Cahit Özcan. The effect of caffeic acid phenethyl ester and Ankaferd Blood Stopper on the diabetic and nondiabetic gingival wound healing: an experimental study. Turkish journal of medical sciences. 2021 04; 51(2):848-856. doi: 10.3906/sag-2007-193. [PMID: 33244945]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Shafi Mahmud, Gobindo Kumar Paul, Mirola Afroze, Shirmin Islam, Swagota Briti Ray Gupt, Mamudul Hasan Razu, Suvro Biswas, Shahriar Zaman, Md Salah Uddin, Mala Khan, Nunzio Antonio Cacciola, Talha Bin Emran, Md Abu Saleh, Raffaele Capasso, Jesus Simal-Gandara. Efficacy of Phytochemicals Derived from Avicennia officinalis for the Management of COVID-19: A Combined In Silico and Biochemical Study. Molecules (Basel, Switzerland). 2021 Apr; 26(8):. doi: 10.3390/molecules26082210. [PMID: 33921289]
Alfredo García-Layana, Sergio Recalde, Maria Hernandez, Maximino J Abraldes, João Nascimento, Emiliano Hernández-Galilea, Begoña Olmedilla-Alonso, Jose Juan Escobar-Barranco, Miguel Angel Zapata, Rufino Silva, Mariana Caballero Arredondo, María Carmen Lopez-Sabater, Silvia Mendez-Martínez, Nieves Pardiñas-Barón, Pilar Calvo, Patricia Fernández-Robredo. A Randomized Study of Nutritional Supplementation in Patients with Unilateral Wet Age-Related Macular Degeneration. Nutrients. 2021 Apr; 13(4):. doi: 10.3390/nu13041253. [PMID: 33920232]
Francesca Luzi, Elisa Pannucci, Mariangela Clemente, Edoardo Grande, Silvia Urciuoli, Annalisa Romani, Luigi Torre, Debora Puglia, Roberta Bernini, Luca Santi. Hydroxytyrosol and Oleuropein-Enriched Extracts Obtained from Olive Oil Wastes and By-Products as Active Antioxidant Ingredients for Poly (Vinyl Alcohol)-Based Films. Molecules (Basel, Switzerland). 2021 Apr; 26(7):. doi: 10.3390/molecules26072104. [PMID: 33917644]
Carolina Alemán-Jiménez, Raúl Domínguez-Perles, Sonia Medina, Iva Prgomet, Iván López-González, Agustín Simonelli-Muñoz, Maria Campillo-Cano, David Auñón, Federico Ferreres, Ángel Gil-Izquierdo. Pharmacokinetics and bioavailability of hydroxytyrosol are dependent on the food matrix in humans. European journal of nutrition. 2021 Mar; 60(2):905-915. doi: 10.1007/s00394-020-02295-0. [PMID: 32524230]
Tomoko Oshima, Michiho Ito. Sedative effects of l-menthol, d-camphor, phenylethyl alcohol, and geraniol. Journal of natural medicines. 2021 Mar; 75(2):319-325. doi: 10.1007/s11418-020-01470-1. [PMID: 33389551]
Riichi Hashimoto, Hiyori Iai, Rie Fujita, Kengo Hanaya, Shuhei Higashibayashi, Hiroyoshi Inoue, Takeshi Sugai. Chemoenzymatic semisynthesis of caffeic acid β-phenethyl ester, an antioxidative component in propolis, from raw coffee bean extract. Bioscience, biotechnology, and biochemistry. 2021 Feb; 85(3):476-480. doi: 10.1093/bbb/zbaa077. [PMID: 33624772]